id author title date pages extension mime words sentences flesch summary cache txt work_crapqdxfgvgyfjmg3vsdd6uhtm Adam Paul Arkin A wise consistency: engineering biology for conformity, reliability, predictability 2013.0 9 .pdf application/pdf 7217 1055 37 complex biological function is likely to be most important involve engineering biology for applications in the gene expression in particular there has been an efflorescence of such families of standardized parts or modular strategies for creation of scalable functional for complex circuits but also represents controlled variations of key performance variables, such as promoter context effect (intrinsic, genetic, host, environmental, sequence optimization for expression control [44], standard elements for affecting molecular folding and solubility [45], and another of other innovations in molecular Context effects are unintended interactions among elements of a synthetic biological An example of characterization and control of genetic context effects. standardized genetic parts to express different genes led to virtual eliminatio to map the interactions between environmental components and each gene that affect fitness and designed Systematic characterization of host biology and synthetic biological part operation across contexts can lead to genetic context effects to achieve reliable and predictable function. ./cache/work_crapqdxfgvgyfjmg3vsdd6uhtm.pdf ./txt/work_crapqdxfgvgyfjmg3vsdd6uhtm.txt