id author title date pages extension mime words sentences flesch summary cache txt 10_1101-2021_02_12_430989 Sofer, Tamar Benchmarking Association Analyses of Continuous Exposures with RNA-seq in Observational Studies 2021 27 .pdf application/pdf 8136 626 48 Benchmarking Association Analyses of Continuous Exposures with RNA-seq in Observational Studies as well as linear regression-based analyses for studying the association of continuous exposures generation of empirical null distribution of association p-values, and we apply the pipeline to Many studies of phenotypes associated with gene expression from RNA-seq consist of small Residual permutation approach for simulations and for empirical p-value computation covariates, and outcome distributions; and (b) their relationships, aside from the exposureoutcome association, are the same as in the real data, we used a residual permutation approach. association studies applied to residual permutations were included to compute empirical papproach to study the distribution of p-values under the null of no association between the phenotypes and RNA-seq, and used this approach to further study power, and to compute approaches for transcriptome-wide analysis of RNA-seq in population-based studies, including more comprehensive study of statistical permutation approaches for RNA-seq association ./cache/10_1101-2021_02_12_430989.pdf ./txt/10_1101-2021_02_12_430989.txt