id author title date pages extension mime words sentences flesch summary cache txt 10_1101-2021_02_09_430460 Banerjee, Shayantan Sequence neighborhoods enable reliable prediction of pathogenic mutations in cancer genomes 2021 39 .pdf application/pdf 15659 1731 40 experimentally validated cancer mutation data in this study, we explored various string-based evolutionary features resulted in the development of a pan-cancer mutation effect prediction Distinguishing between driver and passenger mutations from sequenced cancer genomes is a Recent studies have identified specific signatures or patterns of mutations in different cancer than passenger mutations and built probabilistic models to identify driver genes that had this study, missense mutations from 58 genes that were pan-cancer-based were combined from We used the same datasets to judge our model's ability to predict rare driver mutations based Driver and Passenger Mutations' Features Used to Train NBDriver are Significantly Although our method's focus was to identify missense driver mutations from sequenced cancer surrounding driver and passenger mutations obtained from sequenced cancer genomes. computational prediction of driver missense mutations," Cancer Res., vol. functionally validated cancer-related missense mutations," Genome Biology, vol. Figure 7: Differences in the distribution of features between driver and passenger mutations ./cache/10_1101-2021_02_09_430460.pdf ./txt/10_1101-2021_02_09_430460.txt