id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
10_1101-2021_02_08_430270	Gerard, David	Scalable Bias-corrected Linkage Disequilibrium Estimation Under Genotype Uncertainty	2021	22	.pdf	application/pdf	7219	1582	69	Scalable Bias-corrected Linkage Disequilibrium Estimation Under Genotype Uncertainty Keywords and phrases: attenuation bias, genotype likelihood, linkage disequilibrium, polyploidy, reliability ratio. Let XiA and XiB be the posterior means at loci A and B for individual Equations (5)–(7) take the naive estimators most researchers use in practice (the sample covariance/correlation of posterior means) and inflate these by a multiplicative effect. Gerard and Ferrão, 2019] to obtain the posterior moments for each individual's genotype at each SNP reliability ratios of most SNPs only increase their correlation estimates by less than 10%. To evaluate the LD estimates of high reliability ratio SNPs, we calculated the MLEs for ρ2 applied to simple linear regression with an additive effects model (where the SNP effect is proportional to the dosage), result in the standard ordinary least squares estimates when using the extreme reliability ratio of PotVar0080327, the genotype-error adjusted correlation estimate is -1.	./cache/10_1101-2021_02_08_430270.pdf	./txt/10_1101-2021_02_08_430270.txt