id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
10_1101-2020_09_23_308239	Schultz, Bruce T	The COVID-19 PHARMACOME: A method for the rational selection of drug repurposing candidates from multimodal knowledge harmonization	2021	31	.pdf	application/pdf	8797	1318	57	The COVID-19 PHARMACOME: A method for the rational selection of drug repurposing COVID-19 PHARMACOME, a comprehensive drug-target-mechanism graph generated from a initial version of the COVID-19 PHARMACOME, a comprehensive drug-target-mechanism graph representing COVID-19 pathophysiology mechanisms that includes both drug targets Figure 3: Overlap of compound hits between different drug repurposing screening experiments. space overlap between different COVID-19 drug repurposing screenings. The COVID-19 PHARMACOME associates pathways derived from drug repurposing targets Figure 4 shows the distribution of repurposing drugs in the COVID-19 cause-and-effect graph, overlap analysis allows for the identification of repurposing drugs targeting mechanisms that Virus-response mechanisms are targets for repurposing drugs Figure 5: Visualization of drug repurposing candidates (and their targets) used in combination treatment as our own drug repurposing screening results, we were able to identify mechanisms targeted COVID-19 PHARMACOME, we are now able to link repurposing drugs, their targets and the SARS-CoV-2 protein interaction map reveals targets for drug repurposing.	./cache/10_1101-2020_09_23_308239.pdf	./txt/10_1101-2020_09_23_308239.txt