id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
10_1101-2020_09_02_279521	Abi Nader, Clément	Simulating the outcome of amyloid treatments in Alzheimer’s disease from imaging and clinical data	2021	32	.pdf	application/pdf	12164	1038	56	Simulating the outcome of amyloid treatments in Alzheimer's disease from imaging and clinical data When applied to multimodal imaging and clinical data from the Alzheimer's Disease Neuroimaging Initiative our * Data used in preparation of this article were obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database Keywords : Alzheimer's Disease ; Clinical trials ; Disease progression; Amyloid hypothesis; of large datasets of different data modalities, such as clinical scores, or brain imaging measures to model Alzheimer's disease progression based on specific assumptions on the biochemical combining traditional DPMs with dynamical models of Alzheimer's disease progression. In this work we present a novel computational model of Alzheimer's disease progression to multi-modal imaging and clinical data from the Alzheimer's Disease Neuroimaging To simulate the long-term progression of Alzheimer's disease we first project the AD subjects Figure 3 Model-based progression of Alzheimer's disease. clinical data, based on the estimation of latent biomarkers' relationships governing Alzheimer's 	./cache/10_1101-2020_09_02_279521.pdf	./txt/10_1101-2020_09_02_279521.txt