id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_y6u4hkjd7fbzbakesxg4gaaou4	Amaka C. Offiah	Differential diagnosis of perinatal hypophosphatasia: radiologic perspectives	2018	20	.pdf	application/pdf	9580	2269	67	Perinatal hypophosphatasia (HPP) is a rare, potentially life-threatening, inherited, systemic metabolic bone disease that can be HPP from other skeletal dysplasias, such as sites of angulation of long bones, patterns of hypomineralization, and metaphyseal Hypophosphatasia (HPP) is a rare, inherited, systemic, metabolic bone disease caused by low tissue-nonspecific alkaline phosphatase activity [1–3]. These difficulties are confounded by a general lack of familiarity with HPP among the health care providers who perform prenatal ultrasound (US) and neonatal the role of fetal and neonatal imaging modalities in the differential diagnosis of perinatal HPP. absent ossification of whole bones at or after 11 weeks' gestation is characteristic of severe lethal HPP and is associated with The gestational age at which skeletal abnormalities are apparent in perinatal HPP varies widely, with some cases detected on A retrospective analysis of 77 cases of fetal skeletal dysplasia (including 17 of HPP) in Japan from	./cache/work_y6u4hkjd7fbzbakesxg4gaaou4.pdf	./txt/work_y6u4hkjd7fbzbakesxg4gaaou4.txt