id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_wzcvgebujbhi3gfyfilc453xcu	David W Craig	Identification of disease causing loci using an array-based genotyping approach on pooled DNA	2005	9	.pdf	application/pdf	6821	546	47	better resolve association signals through analysis of neighbouring SNPs. Results: We report the accuracy of allelic frequency measurements on pooled genomic DNA predicting allelic frequencies for each SNP, derived from several thousand individually genotyped It is possible to identify SNPs that have significant differences in allelic frequencies between two populations allelic frequencies of a SNP from a pooled sample on a study, we investigated the reliability of SNP allelic frequency measurements as determined from pooling of genomic DNA to the known allelic frequencies determined by individual genotyping in order to establish the of SNPs at each allele frequency difference between individual and pooled samples. individual genotyped samples show that calculating frequencies from pooled samples is highly accurate, it is perhaps of greater importance that we are able to predict constructing k-correction factors and predicting allelic frequencies will be unreliable for these SNPs, even if pooled	./cache/work_wzcvgebujbhi3gfyfilc453xcu.pdf	./txt/work_wzcvgebujbhi3gfyfilc453xcu.txt