id author title date pages extension mime words sentences flesch summary cache txt work_7ak2zhxmxreonjjhci4hxj5vxm Susan L Neuhausen Founder populations and their uses for breast cancer genetics 2000 5 .pdf application/pdf 4024 439 68 Founder populations and their uses for breast cancer genetics Keywords: BRCA1, BRCA2, breast cancer genes, founder mutations, genetic epidemiology little genetic heterogeneity, so that the majority of individuals with disease will carry the same gene mutation. mutation carriers have been identified the Breast Cancer Few other BRCA1 or BRCA2 mutations have been identified in Jewish breast or ovarian cancer cases. Researchers have suggested studying high-risk Ashkenazi Jewish breast cancer types of studies, utilizing founder populations and mutations, are not unique to breast cancer genetics, and are the breast and ovarian cancer susceptibility gene BRCA1. of carrying a mutation of breast-ovarian cancer gene BRCA1 Anonymous: Cancer risks in BRCA2 mutation carriers. BRCA2 mutations in Finnish breast cancer families. of risk of breast cancer in carriers of BRCA2 mutation. mutations in Canadian breast and ovarian cancer families. founder effects in BRCA1 mutation carrier breast cancer patients germ-line mutations of the BRCA1 gene in ovarian cancer families ./cache/work_7ak2zhxmxreonjjhci4hxj5vxm.pdf ./txt/work_7ak2zhxmxreonjjhci4hxj5vxm.txt