id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_32msqfe5ffddnkntuqw3b7q5ji	Rochelle A. Yanofsky	Ataxia-Telangiectasia: Atypical Presentation and Toxicity of Cancer Treatment	2009	6	.pdf	application/pdf	4774	636	58	cerebellar ataxia, oculocutaneous telangiectasias, immunodeficiency, hypersensitivity to ionizing radiation, and cancer ABSTRACT: Background: The onset of progressive cerebellar ataxia in early childhood is considered a key feature of ataxiatelangiectasia (A-T), accompanied by ocular apraxia, telangiectasias, immunodeficiency, cancer susceptibility and hypersensitivity to neurological abnormalities, with onset by age 30 months, including dysarthria, dyskinesia, hypotonia and/or dystonia, without Cerebellar ataxia was noted in only one of the children and was mild until his death at age eight years. All three children were "cured" of their lymphoid malignancies, but experienced severe adverse effects from the treatments The two children who received cranial irradiation developed supratentorial primitive neuroectodermal tumors of the brain, Ataxia and telangiectasias may be minimal or absent and the course seemingly non-progressive. Table: Results of testing for Ataxia-Telangiectasia (A-T) Ataxia telangiectasia with cancer. Ataxia-telangiectasia and malignancies. Diagnosis of ataxiatelangiectasia: ATM mutation associated with cancer. patients with ataxia-telangiectasia. patients with ataxia-telangiectasia.	./cache/work_32msqfe5ffddnkntuqw3b7q5ji.pdf	./txt/work_32msqfe5ffddnkntuqw3b7q5ji.txt