id author title date pages extension mime words sentences flesch summary cache txt cord-326804-5psqro9d Wei, Chen The focus and timing of COVID-19 pandemic control measures under healthcare resource constraints 2020-04-19 .txt text/plain 4596 295 53 Furthermore, prolonging outbreak duration by applying an intermediate, rather than strict, transmission control would not prevent hospital overload regardless of bed capacity, and would likely result in a high ratio (21% ~ 84%) of the population being infected but not treated. The availability of a complete set of data and detailed records of adopted control policies from Wuhan enables us to construct and test an epidemic model that accounts for the factors deciding an outbreak profile, including the control policy's evolution through time as well as the healthcare system capacity. A modified SEIR model ( Figure 1 ) with time-dependent transmission rate control, timedependent case isolation and testing rate, non-Markovian patient discharge was proposed (see Methods for details). Subsequently, the synergistic effect of increasing transmission control and isolation rate effectively reduced the daily reproduction number (see Suppression success in Methods) to be below 1 by Feb 28, 2020, subsequently resulting in a suppressed COVID-19 transmission ( Figure 2B ). ./cache/cord-326804-5psqro9d.txt ./txt/cord-326804-5psqro9d.txt