id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-278638-2dm54f6l	Huang, Ian	Lymphopenia in severe coronavirus disease-2019 (COVID-19): systematic review and meta-analysis	2020-05-24		.txt	text/plain	3105	207	52	Research articles in adult patients diagnosed with COVID-19 with information on lymphocyte count and several outcomes of interest, including mortality, acute respiratory distress syndrome (ARDS), intensive care unit (ICU) care, and severe COVID-19, were included in the analysis. We used standardized forms that included author, year, study design, age, gender, cardiac comorbidities, hypertension, diabetes mellitus, chronic obstructive pulmonary disease, smoking, lymphocyte count, lymphopenia, mortality, ARDS, ICU care, and severe COVID-19. Random-effects meta-regression analysis showed that the association between lower lymphocyte count in patients with composite poor outcome was affected by age (p = 0.034) (Fig. 3a) , but not by gender (p = 0.109), cardiac comorbidity (p = 0.953) (Fig. 3b) , hypertension (p = 0.065) (Fig. 3c) , diabetes mellitus (p = 0.931), COPD (p = 0.798), and smoking (p = 0.581). This meta-analysis showed that lower lymphocyte count was associated with increased mortality, ARDS, need for ICU care, and severe COVID-19.	./cache/cord-278638-2dm54f6l.txt	./txt/cord-278638-2dm54f6l.txt