key: cord-272001-er7lvhn5
authors: Farewell, Charlotte V.; Jewell, Jennifer; Walls, Jessica; Leiferman, Jenn A.
title: A Mixed-Methods Pilot Study of Perinatal Risk and Resilience During COVID-19
date: 2020-07-16
journal: J Prim Care Community Health
DOI: 10.1177/2150132720944074
sha: 
doc_id: 272001
cord_uid: er7lvhn5

Introduction/Objectives: National guidelines underscore the need for improvement in the detection and treatment of mood disorders in the perinatal period. Exposure to disasters can amplify perinatal mood disorders and even have intergenerational impacts. The primary aim of this pilot study was to use mixed-methods to better understand the mental health and well-being effects of the coronavirus disease 2019 (COVID-19) pandemic, as well as sources of resilience, among women during the perinatal period. Methods: The study team used a simultaneous exploratory mixed-methods design to investigate the primary objective. Thirty-one pregnant and postpartum women participated in phone interviews and were invited to complete an online survey which included validated mental health and well-being measures. Results: Approximately 12% of the sample reported high depressive symptomatology and 60% reported moderate or severe anxiety. Forty percent of the sample reported being lonely. The primary themes related to stress were uncertainty surrounding perinatal care, exposure risk for both mother and baby, inconsistent messaging from information sources and lack of support networks. Participants identified various sources of resilience, including the use of virtual communication platforms, engaging in self-care behaviors (eg, adequate sleep, physical activity, and healthy eating), partner emotional support, being outdoors, gratitude, and adhering to structures and routines. Conclusions: Since the onset of COVID-19, many pregnant and postpartum women report struggling with stress, depression, and anxiety symptomatology. Findings from this pilot study begin to inform future intervention work to best support this highly vulnerable population.

Pregnancy and the first 6 months postpartum (perinatal period) can be inherently challenging, often leading to lack of sleep, relationship tensions, and feelings of isolation. 1 These challenges result in the development of mood disorders for many women. For example, the prevalence of prenatal and postpartum depression is estimated at 12% and 17%, respectively. [2] [3] [4] Exposure to environmental stressors, such as natural disasters, can amplify perinatal mood disorders and even have intergenerational impacts on child health and development outcomes. [5] [6] [7] [8] Health care providers are often the primary source of mental health resources and care for women during the perinatal period, 9 indicating a significant role of providers in helping to identify and manage (eg, treat/refer) perinatal mood disorders. 10, 11 However, a prior study found that maternal depression is assessed in primary care settings less than 50% of the time, and the use of screening tools is even lower (22%-46%). 12 National guidelines underscore the need for improvement in the detection and treatment of mood disorders in the perinatal period, particularly among those vulnerable to environmental stressors. 10, 11 Many studies have explored the impacts of disasters, or events that cause disruption exceeding the adjustment capacity of the affected community, 13 on mental health and have found that prenatal and postpartum women may experience significantly higher rates of mood disorders during disasters compared with the general population. 14, 15 In January 2020, the World Health Organization (WHO) declared the outbreak of a new coronavirus disease, COVID-19, to be a public health emergency of international concern. According to similar epidemics and pandemics, stress coupled with feelings of loneliness and anger can develop among people who are quarantined. 16 Additionally, social isolation during environmental disasters, such as COVID-19, may lead to decreased social connections, which can further exacerbate feelings of isolation and perinatal mood disorders. 17 Although current studies are exploring the specific impacts of COVID-19 on population mental health, 18 less is known about the mental health implications specifically related to perinatal mental health during COVID-19. Additionally, better understanding of potential factors that may be protective for perinatal women during a pandemic, such as social supports and/or coping strategies is warranted. 14 Resilience in the face of disasters is likely to result from a combination of resources that foster the ability to cope well despite extraordinarily severe demands. 19 The primary aim of this pilot study was to use mixed-methods to better understand mental health and well-being, as well as sources of resilience, for women in the perinatal period during the COVID-19 pandemic. These findings have implications related to prenatal and postpartum health care among women exposed to disasters and large-scale traumatic events.

Ethical approval for this pilot study was obtained from the Colorado Multiple Institutional Review Board (#20-0840). Rolling recruitment for this study occurred between March and April 2020 using a purposive, nonprobabilistic sampling method. The targeted audience for this study included mothers who met the following criteria: (1) over the age of 18 years, (2) English-speaking, (3) currently living in Colorado, and (4) being pregnant or within the first 6-months postpartum. Women were recruited through advertisements posted on social media outlets (eg, Facebook, mom listservs). Women who met the eligibility criteria and who were interested in participating in the study completed an online consent form. Women were contacted by a member of the study team to schedule a time for a phone interview within 48 hours of completing the online consent form.

The study team used a simultaneous exploratory mixedmethods design to investigate the primary objective. 20 Qualitative Methods. Prior to the interview, participants were provided information about how the interview would be conducted. Two members of the research team conducted the phone interviews (first, CVF, and last author, JAL); interviews averaged 24 minutes, ranging from 17 to 43 minutes. The interview protocol consisted of a semistructured tool including a combination of open-ended questions related to sources of stress, sources of support and coping, self-care and well-being, beliefs around COVID risks, and impacts on care plans. Example questions included, "In general, how has the COVID-19 pandemic impacted your pregnancy experience thus far?" and "How has the pandemic changed your expectations around parenting?" Participants were provided mental health resources at the conclusion of interviews.

Qualitative Analysis. The 2 interviewers took extensive notes throughout the phone interviews. Qualitative data analysis followed best practice methods for qualitative research, including a deductive, theory-driven approach, and an inductive, data-driven approach. 21, 22 One of the interviewers (first author, CVF) coded the interviews using NVIVO software and constant comparison analysis. 23 The codebook contained a priori codes that aligned with sources of stress (eg, social isolation) and resilience (eg, social supports) from the literature. Inductive coding was also used to allow for discovery of unique sources of risk and resilience. A second coder (JAL) reviewed all transcripts, summarized themes and subthemes and compared findings with the first coder. If disconcordance on the meaning of the codes and themes were present, a discussion occurred between the coders to reach consensus on the coding structure.

Quantitative Methods. After completing the interview, participants were sent an electronic link to a 70-item online survey. The survey took approximately 15 minutes to complete. The survey included measures of sociodemographic factors, coping behaviors, and several validated measures for mental health and well-being, including: the Patient Health Questionnaire-2 (PHQ-2), which is a brief measure of depression with a range of 0 to 6 and a cutoff score of ≥3; 24 the Generalized Anxiety Disorder-7 (GAD-7) scale, which is a brief measure of anxiety with a range of 0 to 21 and a cutoff score of ≥10; 25 the Brief Resilience Scale (BRS), which measures resilience and ranges from 1 to 5 with higher scores indicating more resilience; 26 the Warwick-Edinburgh Mental Wellbeing Scale (WEMWBS), which measures subjective well-being and ranges from 14 to 70 with higher scores indicating higher well-being; 27 and the 3-item Loneliness Scale, which measures loneliness and has a cutoff of ≥6 and a range of 3 to 9. 28 After completion of both the phone interview and online survey, participants were randomly selected to receive 1 of 2 USD50 gift cards.

Quantitative Analysis. Descriptive statistics were conducted to investigate the primary variables of interest in the quantitative data, including demographics, mental health and well-being measures and reported coping behaviors.

Thirty-one interviews were conducted and 27 of the 31 participants completed the online survey. Approximately half of the interview participants were pregnant (52%) and half were within 6 months postpartum (48%). Fifty percent of the pregnant sample were primigravid and 38% of the postpartum sample had only one child. Table 1 displays sample characteristics of the participants who completed the survey and descriptives related to the primary variables of interest. Approximately 12% of the sample reported high depressive symptomology and 60% reported moderate or severe anxiety symptomatology. About two-thirds of the sample (68%) reported experiencing at least moderate stress, and participants scored an average of 46 on the well-being scale (range = 34-61) and an average of 3.0 on the resilience scale (range = 2.3-3.7). Forty percent of the sample reported being lonely. Participants reported that the most common ways they were coping included texting with friends (79%), video/phone calls with friends (68%) and sleeping (61%).

The primary themes, subthemes, and illustrative quotes from the qualitative data are summarized in Table 2 .

Pregnant women most commonly expressed stress surrounding "unknowns" related to prenatal care appointment rules, birth plan expectations, and prenatal exposure risk. For example, one woman shared, "I anticipate the birthing experience will be quite different, and I'm just hoping the hospital I'm delivering in will allow my husband to be there. It's just not knowing what's going to happen right now." Among new mothers, uncertainty and stress were related to newborn risk exposure. One mother said, "and when it comes to health, like with having a new baby, I'm not an expert and I don't know how worried I should be. I need someone to tell me . . ."

Lack of consistent messaging and clear guidance surrounding recommendations and care appointments from providers was a concern shared by both pregnant women and new mothers. One pregnant woman said, "I feel like we get all these mixed-messages about it." Another pregnant woman said, "I mean online appointments have been fine, but I guess the healthcare system doesn't really know what they're doing, and they are trying to be nimble and they haven't let me know in advance about who I'm seeing or if I'm allowed to come in until the last minute."

Pregnant women reported feelings of isolation and loneliness as well as lack of postpartum support networks. Women shared that being pregnant during COVID-19 resulted in less excitement surrounding the pregnancy because of social isolation. One woman said, "It's made it definitely a more somber experience and it has been difficult to be excited because you can't share it with people." Pregnant women also talked about concerns over postpartum supports. One woman shared, "Well, we were counting on support from grandparents on both sides and we can't anymore." New moms frequently cited stressors related to lack of daycare and caregiver supports, and social isolation. One mother said, "It has made it a lot harder, mainly that I don't have childcare and I was planning on going back to work but now I can't." New moms shared that social isolation was significantly affecting their postpartum mental health. A mother said, "And now feeling even more isolated than normal because if we go for a walk now I use the ergobaby instead of the stroller so I can keep her covered."

Pregnant women and new moms shared that partner support was the primary factor that helped them cope. One new mom shared, "we [partners] are alternating like some days he's stressed and anxious and sometimes I will be. And we're like we need to get through this together." Emotional support was cited as the most helpful source of support among all mothers. One mom said, "being able to connect with newer moms with similar aged babies and go around and share with everyone on Zoom." All women shared that getting outdoors and being in nature was helping them cope. One pregnant woman said, "Just being outside. I always go to the park and just breathe." Women also said that focusing on gratitude promoted their mental health. For example, one new mom said, "feeling grateful for all this special time with my kids and to have all this intense family time." Finally, women in both the prenatal and postpartum periods shared that managing expectations was protective. One pregnant woman shared, "just sort of having to adjust expectations because none of this is how we imagined pregnancy would be."

Among new mothers, structures and routines were cited as a factor that helped them cope. One mom said, "So completely resetting daily routines and coordinating work schedules and full-time parenting" and "staying on schedule has helped with staying mentally well too."

Participants shared a variety of positive impacts related to the COVID-19 pandemic. Pregnant woman said that being able to work from home allowed for more time to prioritize self-care, which improved their mental and physical health. New mothers highlighted numerous positive benefits including increased connection and bonding with their immediate family unit, partner supports in the home to share caregiving responsibilities, and increased access to remote postnatal and postpartum care. One mom said, "My husband is home full-time and that has been so helpful just to not be alone. I can really focus on her and my husband and our family time." Another mother shared, I've been connected with postpartum behavioral health support and that has been virtual which is really great actually because I'm not sure how otherwise I would be able to go. In that way it has allowed me to seek those types of services more.

Both pregnant women and new mothers shared additional positive impacts of the COVID-19 pandemic including not missing out on social activities and spending less money. One mom said, "I think the biggest positive is that I didn't have that feeling of missing out . . . my friends weren't posting cool things that I was missing out on," and a pregnant woman said, "We are spending less because we aren't going out."

These findings highlight the additional toll of the COVID-19 pandemic on perinatal mental health in the United States. The quantitative findings suggest that the pandemic has resulted in elevated rates of mood disorders for this sample of pregnant and postpartum women. Perinatal anxiety rates were approximately six times higher in this sample compared to pre-pandemic perinatal rates in Colorado. 29 Additionally, participants reported lower well-being 30 and lower levels of resilience compared to pre-pandemic scores. 26 The qualitative component of this study illustrated sources of stress that further explain these quantitative findings. The burden of uncertainty related to health care services and risk exposure for all women was a salient theme. Harville et al 31 similarly found that after Hurricane Katrina, stressors experienced by perinatal women included the interruption of health care services, clinical infrastructure and referrals and the lack of knowledge surrounding early term exposure. Alternative studies found that uncertainties lead to heightened fears of contracting or transmitting infection 32 and fears surrounding separation from the infant at birth. 33 Almost half of the sample reported feeling lonely, and this social isolation may explain the high rates of anxiety and poor well-being and resilience reported in this sample of pregnant and postpartum women. 34 Social isolation was a common theme shared by both pregnant and postpartum women in the qualitative data and align with the prevalence of loneliness reported in the sample. Social distancing and isolation during disasters, coupled with lack of access to health care professionals, can lead to heightened intimate partner violence, 35, 36 which can affect maternal mood disorders and adverse pregnancy and birth outcomes. 37 Additionally, lack of caregiver social supports in the postpartum period are linked to poor maternal psychological well-being. 38 Sources of resilience were identified in these data and are supported by past research that has explored resilience among perinatal women during disasters. Virtual media platforms (texting, video calls), 39, 40 and engaging in selfcare behaviors such as getting recommended sleep and exercise 41 were identified as protective coping behaviors in the quantitative data. Qualitative data suggested that social support, and specifically partner and emotional support, 42 gratitude and optimism, 43, 44 and the management or shifting of expectations 45 were significant protective factors for pregnant and postpartum women, particularly during exposure to significant environmental stressors. 42 However, the high rates of depression, anxiety, and stress identified in this sample suggest that quarantine and social isolation regulations may increase need for supports and protective coping behaviors. 32 Limitations of this pilot study include the small sample size, minimal diversity, lack of consideration of pregnancy and birth complications, and the recruitment strategy, which relied solely on social media platforms and may limit the generalizability of these findings. Additionally, approximately half of the pregnant sample were pregnant with their first baby and over a third of the postpartum sample were first-time moms. Mental health and associated factors may vary by primigravid and multigravida women. [46] [47] [48] Larger studies are needed to increase generalizability and to compare the unique experiences of stress during COVID-19 among these 2 different groups. However, this study may have implications for health care providers who are providing care for pregnant and postpartum women during the COVID-19 pandemic. Table 3 displays provider recommendations to help mitigate perinatal mood disorders and promote resilience based on these preliminary findings. Examples include screening all perinatal women for depression and anxiety during healthcare visits and providing positive coping behavior recommendations via hand-outs during prenatal and postpartum care visits. Collectively, these data suggest that COVID-19 has amplified the rates of perinatal mood disorders among this sample of perinatal women. • Alert pregnant women to information regarding appointment rules and regulations (eg, supports) as early as possible in the pregnancy • • Address uncertainty surrounding COVID-19 and impacts on perinatal health and direct to evidence-based sources of information • • Screen all prenatal and postpartum women for depression/anxiety during health care visits Promote perinatal resilience and positive coping • • Provide coping suggestions and recommendations in the form of hand-outs/one-pagers during prenatal and postpartum care visits. Recommended topics include remote and safe ways to promote social connection, outdoors benefits, gratitude, managing expectations related to birthing/delivery, and self-care behaviors (physical activity, stress management, sleep) • • Increase opportunities for social connection during prenatal and postpartum tele-health classes • • Provide resources related to mental health supports and care for all prenatal and postpartum women

Exposure to prenatal psychobiological stress exerts programming influences on the mother and her fetus

Prevalence and incidence of postpartum depression among healthy mothers: a systematic review and meta-analysis

A systematic review and meta-regression of the prevalence and incidence of perinatal depression

Depressive symptoms in parents of children under age 3: sociodemographic predictors, current correlates, and associated parenting behaviors

Developmental origins of adult function and health: evolutionary hypotheses

Prenatal stress exposure and early childhood BMI: exploring associations in a New Zealand context

Exploring the timing and duration of maternal stress exposure: impacts on early childhood BMI

Disaster-related prenatal maternal stress explains increasing amounts of variance in body composition through childhood and adolescence: Project Ice Storm

Women's preferred sources for primary and mental health care: implications for reproductive health providers. Women's Health Issues

American College of Obstetricians and Gynecologists. ACOG Committee opinion no. 549: obesity in pregnancy

Perinatal depression: a review of US legislation and law

Postpartum depression screening: Importance, methods, barriers, and recommendations for practice

Disasters and perinatal health: a systematic review

Psychiatric disorders in pregnant and postpartum women in the United States

Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed

Recommended psychological crisis intervention response to the 2019 novel coronavirus pneumonia outbreak in China: a model of West China Hospital

Iranian mental health during the COVID-19 epidemic

Transactional theory and research on emotions and coping

Simultaneous and sequential qualitative mixed method designs

Qualitative Methods for Health Research. Sage

Designing a qualitative study

NVivo qualitative data analysis software

Validation of PHQ-2 and PHQ-9 to screen for major depression in the primary care population

A brief measure for assessing generalized anxiety disorder: the GAD-7

The brief resilience scale: assessing the ability to bounce back

The Warwick-Dinburgh mental well-being scale (WEMWBS): development and UK validation

A short scale for measuring loneliness in large surveys: results from two population-based studies

Societal costs of untreated perinatal mood and anxiety disorders in the United States

Associations between social support, mental wellbeing, self-efficacy and technology use in first-time antenatal women: data from the BaBBLeS cohort study

Postpartum mental health after Hurricane Katrina: a cohort study

The psychological impact of quarantine and how to reduce it: rapid review of the evidence

Should infants be separated from mothers with COVID-19? First, do no harm

The Encyclopedia of Child and Adolescent Development

Danger in danger: interpersonal violence during Covid-19 quarantine

A systematic review and meta-analysis of intimate partner violence during pregnancy and selected birth outcomes

Intimate partner violence during pregnancy and the risk for adverse infant outcomes: a systematic review and meta-analysis

Grandparent support of mothers caring for a child with a disability: impacts for maternal mental health

Disaster resilience among war-affected people resettled in Northern Sri Lanka: challenges revisited

Mental health and worries of pregnant women living through disaster recovery

Psychological first aid: a model for disaster psychosocial support for the perinatal population

Social support-a protective factor for depressed perinatal women?

Keeping it together, keeping their heads above water": Western Australian child health nurses' understanding of resilience in postpartum mothers

Dialectical behavior therapy-based psychological intervention for woman in late pregnancy and early postpartum suffering from COVID-19: a case report

Posttraumatic growth: conceptual foundations and empirical evidence

Anxiety on primigravid women attending antenatal care: a hospital based cross-sectional study

Primigravid and multigravid women: prenatal perspectives

Fear of childbirth in primiparous Italian pregnant women: The role of anxiety, depression, and couple adjustment

We acknowledge all pregnant and postpartum women who participated in this study and shared their experiences.