id author title date pages extension mime words sentences flesch summary cache txt cord-282636-u0ea02fc Zuo, Y. Neutrophil extracellular traps and thrombosis in COVID-19 2020-05-05 .txt text/plain 1704 117 39 For three patients, we were able to test sera for neutrophil extracellular trap (NET) remnants and found significantly elevated levels of cell-free DNA, myeloperoxidase-DNA complexes, and citrullinated histone H3. Given strong links between hyperactive neutrophils, NET release, and thrombosis in many inflammatory diseases, the potential relationship between NETs and VTE should be further investigated in COVID-19. Neutrophil-derived neutrophil extracellular traps (NETs) play a pathogenic role in many thrombo-inflammatory states including sepsis 4, 5 , thrombosis [6] [7] [8] , and respiratory failure 9, 10 . We identified four patients admitted to a large academic medical center with COVID-19 who also developed VTE (either deep vein thrombosis or pulmonary embolism) despite immediate initiation of prophylactic-dose heparin. 30.20086736 doi: medRxiv preprint elevated by the time the patient was diagnosed with deep vein thrombosis on day 20 ( Table 2) . Vivo Role of Neutrophil Extracellular Traps in Antiphospholipid Antibody-Mediated Venous Thrombosis ./cache/cord-282636-u0ea02fc.txt ./txt/cord-282636-u0ea02fc.txt