id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-290243-m8yfugr0	Kim, Kyung Ran	Design, synthesis, and biological evaluation of novel iso-d-2′,3′-dideoxy-3′-fluorothianucleoside derivatives	2007-01-01		.txt	text/plain	3390	184	59	The resulting residue was purified by silica gel column chromatography using hexane and ethyl acetate (5:1) as the eluent to give the corresponding alcohol 8 (5.570 g, 95%) as a colorless oil: ½a To a stirred solution of alcohol 8 (3.050 g, 6.19 mmol) in anhydrous CH 2 Cl 2 (20 mL) was dropwise added (dieth-ylamino)sulfur trifluoride (DAST, 1.23 mL, 9.31 mmol) at À10°C and the reaction mixture was stirred at the same temperature for 30 min. After the volatiles were removed in vacuo, the resulting residue was purified by silica gel column chromatography using hexane and ethyl acetate (3:1) as the eluent to give To a stirred solution of 13 (110 mg, 0.19 mmol) in methanol (4.5 mL) and CH 2 Cl 2 (1.5 mL) was added 1 M NaOMe (0.40 mL, 0.40 mmol, in MeOH) at 0°C and the reaction mixture was stirred for 6 h at room temperature.	./cache/cord-290243-m8yfugr0.txt	./txt/cord-290243-m8yfugr0.txt