id author title date pages extension mime words sentences flesch summary cache txt cord-263749-bbhh5xb1 Larenas-Linnemann, Désirée Enhancing innate immunity against virus in times of COVID-19: trying to untangle facts from fictions 2020-10-09 .txt text/plain 4122 239 40 We divide the reviewed interventions in: 1) lifestyle related (exercise, >7 hours sleep, forest walking, meditation/mindfulness, vitamin supplementation); 2) Non-specific immune stimulants (letting fever advance, bacterial vaccines, probiotics, dialyzable leukocyte extract, pidotimod) and 3) specific vaccines with heterologous effect (BCG vaccine, mumps-measles-rubeola vaccine, i.e.). The complete mechanism by which zinc could decrease the number or severity of viral infectious 308 processes in general and of COVID-19 in particular is not exactly understood yet; however, effects have 309 been observed on the binding of the viral agent to the mucosa and on its replication, as well as on the 310 regulation of the inflammatory process;(73) enhanced benefits have been hypothesized when co-311 administered with other medications such as (hydroxy)chloroquine that could function as a ionophore, 312 facilitating the entrance of zinc into the cells.(74) The human body's ability to store zinc is known to be 313 low; its deficiency compromises the immune system, as has been evidenced occasionally by thymic 314 atrophy, lymphopenia and altered lymphocyte responses. ./cache/cord-263749-bbhh5xb1.txt ./txt/cord-263749-bbhh5xb1.txt