id author title date pages extension mime words sentences flesch summary cache txt cord-005428-pm7ihh9t Amrein, Karin Vitamin D deficiency 2.0: an update on the current status worldwide 2020-01-20 .txt text/plain 6940 333 39 As there is no evidence that increasing the recommended daily dose of vitamin D supplementation up to 50 μg (2000 IU) would cause severe side effects in the general population, and considering that 20 μg (800 IU) is the lowest dose consistently associated with a bone benefit, it seems reasonable to recommend a daily dose of 20-50 μg (800-2000 IU) (levels 2-4 evidence, grades B-D recommendation) [39] . However, several studies in recent years have highlighted that women are at high risk for vitamin D deficiency, and this is associated with adverse pregnancy outcomes, including preeclampsia and gestational diabetes [76] [77] [78] [79] [80] . VIOLET randomized patients with 25 (OH)D levels below 50 nmol/L (or 20 ng/ml) "at risk for ARDS" to one single high dose of vitamin D3 (540,000 IU), and evaluated its effect on the primary outcome: 90-day mortality. ./cache/cord-005428-pm7ihh9t.txt ./txt/cord-005428-pm7ihh9t.txt