id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-317508-03u2vtzk	Oldstone, M.B.A.	History of Virology	2019-08-28		.txt	text/plain	1347	73	53	were clinically evident in early human history, the initial isolation of individual viruses and their assignment to specific diseases did not occur until about 1898, 120 years ago, a proverbial drop in the bucket of time. Although the majority of life-threatening and debilitating acute virus infections are now controlled through vaccination, it is worthwhile considering the consequences of acute infections like smallpox, measles, and yellow fever in the prevaccine era. This devastating depopulation came primarily from smallpox and measles infections, since these viruses had never before existed in the New World (Oldstone, 2010) . However, measles virus infection was and remains a serious disease today with approximately one per thousand infected persons developing severe destruction of the central nervous system requiring institutionalization. Now these and many other acute virus infections are controlled by vaccination or antivirals and public health policies when and where they are instituted.	./cache/cord-317508-03u2vtzk.txt	./txt/cord-317508-03u2vtzk.txt