id	sid	tid	token	lemma	pos
cord-306424-gf0bglm0	1	1	key	key	NN
cord-306424-gf0bglm0	1	2	:	:	:
cord-306424-gf0bglm0	2	1	cord-306424-gf0bglm0	cord-306424-gf0bglm0	NNP
cord-306424-gf0bglm0	2	2	authors	author	NNS
cord-306424-gf0bglm0	2	3	:	:	:
cord-306424-gf0bglm0	2	4	Scutigliani	Scutigliani	NNP
cord-306424-gf0bglm0	2	5	,	,	,
cord-306424-gf0bglm0	2	6	Enzo	Enzo	NNP
cord-306424-gf0bglm0	2	7	Maxim	Maxim	NNP
cord-306424-gf0bglm0	2	8	;	;	:
cord-306424-gf0bglm0	2	9	Kikkert	Kikkert	NNP
cord-306424-gf0bglm0	2	10	,	,	,
cord-306424-gf0bglm0	2	11	Marjolein	Marjolein	NNP
cord-306424-gf0bglm0	2	12	title	title	NN
cord-306424-gf0bglm0	2	13	:	:	:
cord-306424-gf0bglm0	2	14	Interaction	interaction	NN
cord-306424-gf0bglm0	2	15	of	of	IN
cord-306424-gf0bglm0	2	16	the	the	DT
cord-306424-gf0bglm0	2	17	innate	innate	JJ
cord-306424-gf0bglm0	2	18	immune	immune	JJ
cord-306424-gf0bglm0	2	19	system	system	NN
cord-306424-gf0bglm0	2	20	with	with	IN
cord-306424-gf0bglm0	2	21	positive	positive	JJ
cord-306424-gf0bglm0	2	22	-	-	HYPH
cord-306424-gf0bglm0	2	23	strand	strand	NN
cord-306424-gf0bglm0	2	24	RNA	RNA	NNP
cord-306424-gf0bglm0	2	25	virus	virus	NN
cord-306424-gf0bglm0	2	26	replication	replication	NN
cord-306424-gf0bglm0	2	27	organelles	organelle	NNS
cord-306424-gf0bglm0	2	28	date	date	NN
cord-306424-gf0bglm0	2	29	:	:	:
cord-306424-gf0bglm0	2	30	2017	2017	CD
cord-306424-gf0bglm0	2	31	-	-	HYPH
cord-306424-gf0bglm0	2	32	06	06	CD
cord-306424-gf0bglm0	2	33	-	-	SYM
cord-306424-gf0bglm0	2	34	27	27	CD
cord-306424-gf0bglm0	2	35	journal	journal	NN
cord-306424-gf0bglm0	2	36	:	:	:
cord-306424-gf0bglm0	3	1	Cytokine	Cytokine	NNP
cord-306424-gf0bglm0	3	2	Growth	Growth	NNP
cord-306424-gf0bglm0	3	3	Factor	Factor	NNP
cord-306424-gf0bglm0	3	4	Rev	Rev	NNP
cord-306424-gf0bglm0	3	5	DOI	DOI	NNP
cord-306424-gf0bglm0	3	6	:	:	:
cord-306424-gf0bglm0	3	7	10.1016	10.1016	CD
cord-306424-gf0bglm0	3	8	/	/	SYM
cord-306424-gf0bglm0	3	9	j.cytogfr.2017.05.007	j.cytogfr.2017.05.007	NN
cord-306424-gf0bglm0	3	10	sha	sha	NN
cord-306424-gf0bglm0	3	11	:	:	:
cord-306424-gf0bglm0	3	12	8782deab94c366e223e7a6307c1e002ed6cf1c21	8782deab94c366e223e7a6307c1e002ed6cf1c21	CD
cord-306424-gf0bglm0	3	13	doc_id	doc_id	CD
cord-306424-gf0bglm0	3	14	:	:	:
cord-306424-gf0bglm0	3	15	306424	306424	CD
cord-306424-gf0bglm0	3	16	cord_uid	cord_uid	NNS
cord-306424-gf0bglm0	3	17	:	:	:
cord-306424-gf0bglm0	3	18	gf0bglm0	gf0bglm0	NNP
cord-306424-gf0bglm0	4	1	The	the	DT
cord-306424-gf0bglm0	4	2	potential	potential	JJ
cord-306424-gf0bglm0	4	3	health	health	NN
cord-306424-gf0bglm0	4	4	risks	risk	NNS
cord-306424-gf0bglm0	4	5	associated	associate	VBN
cord-306424-gf0bglm0	4	6	with	with	IN
cord-306424-gf0bglm0	4	7	(	(	-LRB-
cord-306424-gf0bglm0	4	8	re-)emerging	re-)emerging	NN
cord-306424-gf0bglm0	5	1	positive	positive	JJ
cord-306424-gf0bglm0	5	2	-	-	HYPH
cord-306424-gf0bglm0	5	3	strand	strand	NN
cord-306424-gf0bglm0	5	4	RNA	RNA	NNP
cord-306424-gf0bglm0	5	5	(	(	-LRB-
cord-306424-gf0bglm0	5	6	+	+	CC
cord-306424-gf0bglm0	5	7	RNA	RNA	NNP
cord-306424-gf0bglm0	5	8	)	)	-RRB-
cord-306424-gf0bglm0	5	9	viruses	virus	NNS
cord-306424-gf0bglm0	5	10	emphasizes	emphasize	VBZ
cord-306424-gf0bglm0	5	11	the	the	DT
cord-306424-gf0bglm0	5	12	need	need	NN
cord-306424-gf0bglm0	5	13	for	for	IN
cord-306424-gf0bglm0	5	14	understanding	understand	VBG
cord-306424-gf0bglm0	5	15	host	host	NN
cord-306424-gf0bglm0	5	16	-	-	HYPH
cord-306424-gf0bglm0	5	17	pathogen	pathogen	NN
cord-306424-gf0bglm0	5	18	interactions	interaction	NNS
cord-306424-gf0bglm0	5	19	for	for	IN
cord-306424-gf0bglm0	5	20	these	these	DT
cord-306424-gf0bglm0	5	21	viruses	virus	NNS
cord-306424-gf0bglm0	5	22	.	.	.
cord-306424-gf0bglm0	6	1	The	the	DT
cord-306424-gf0bglm0	6	2	innate	innate	JJ
cord-306424-gf0bglm0	6	3	immune	immune	JJ
cord-306424-gf0bglm0	6	4	system	system	NN
cord-306424-gf0bglm0	6	5	forms	form	VBZ
cord-306424-gf0bglm0	6	6	the	the	DT
cord-306424-gf0bglm0	6	7	first	first	JJ
cord-306424-gf0bglm0	6	8	line	line	NN
cord-306424-gf0bglm0	6	9	of	of	IN
cord-306424-gf0bglm0	6	10	defense	defense	NN
cord-306424-gf0bglm0	6	11	against	against	IN
cord-306424-gf0bglm0	6	12	pathogenic	pathogenic	JJ
cord-306424-gf0bglm0	6	13	organisms	organism	NNS
cord-306424-gf0bglm0	6	14	like	like	IN
cord-306424-gf0bglm0	6	15	these	these	DT
cord-306424-gf0bglm0	6	16	and	and	CC
cord-306424-gf0bglm0	6	17	is	be	VBZ
cord-306424-gf0bglm0	6	18	responsible	responsible	JJ
cord-306424-gf0bglm0	6	19	for	for	IN
cord-306424-gf0bglm0	6	20	detecting	detect	VBG
cord-306424-gf0bglm0	6	21	pathogen	pathogen	NN
cord-306424-gf0bglm0	6	22	-	-	HYPH
cord-306424-gf0bglm0	6	23	associated	associate	VBN
cord-306424-gf0bglm0	6	24	molecular	molecular	JJ
cord-306424-gf0bglm0	6	25	patterns	pattern	NNS
cord-306424-gf0bglm0	6	26	(	(	-LRB-
cord-306424-gf0bglm0	6	27	PAMPs	pamp	NNS
cord-306424-gf0bglm0	6	28	)	)	-RRB-
cord-306424-gf0bglm0	6	29	.	.	.
cord-306424-gf0bglm0	7	1	Viral	Viral	NNP
cord-306424-gf0bglm0	7	2	RNA	RNA	NNP
cord-306424-gf0bglm0	7	3	is	be	VBZ
cord-306424-gf0bglm0	7	4	a	a	DT
cord-306424-gf0bglm0	7	5	potent	potent	JJ
cord-306424-gf0bglm0	7	6	inducer	inducer	NN
cord-306424-gf0bglm0	7	7	of	of	IN
cord-306424-gf0bglm0	7	8	antiviral	antiviral	JJ
cord-306424-gf0bglm0	7	9	innate	innate	JJ
cord-306424-gf0bglm0	7	10	immune	immune	JJ
cord-306424-gf0bglm0	7	11	signaling	signaling	NN
cord-306424-gf0bglm0	7	12	,	,	,
cord-306424-gf0bglm0	7	13	provoking	provoke	VBG
cord-306424-gf0bglm0	7	14	an	an	DT
cord-306424-gf0bglm0	7	15	antiviral	antiviral	JJ
cord-306424-gf0bglm0	7	16	state	state	NN
cord-306424-gf0bglm0	7	17	by	by	IN
cord-306424-gf0bglm0	7	18	directing	direct	VBG
cord-306424-gf0bglm0	7	19	expression	expression	NN
cord-306424-gf0bglm0	7	20	of	of	IN
cord-306424-gf0bglm0	7	21	interferons	interferon	NNS
cord-306424-gf0bglm0	7	22	(	(	-LRB-
cord-306424-gf0bglm0	7	23	IFNs	ifns	NN
cord-306424-gf0bglm0	7	24	)	)	-RRB-
cord-306424-gf0bglm0	7	25	and	and	CC
cord-306424-gf0bglm0	7	26	pro	pro	JJ
cord-306424-gf0bglm0	7	27	-	-	JJ
cord-306424-gf0bglm0	7	28	inflammatory	inflammatory	JJ
cord-306424-gf0bglm0	7	29	cytokines	cytokine	NNS
cord-306424-gf0bglm0	7	30	.	.	.
cord-306424-gf0bglm0	8	1	However	however	RB
cord-306424-gf0bglm0	8	2	,	,	,
cord-306424-gf0bglm0	8	3	+	+	CC
cord-306424-gf0bglm0	8	4	RNA	RNA	NNP
cord-306424-gf0bglm0	8	5	viruses	virus	NNS
cord-306424-gf0bglm0	8	6	developed	develop	VBD
cord-306424-gf0bglm0	8	7	various	various	JJ
cord-306424-gf0bglm0	8	8	methods	method	NNS
cord-306424-gf0bglm0	8	9	to	to	TO
cord-306424-gf0bglm0	8	10	avoid	avoid	VB
cord-306424-gf0bglm0	8	11	detection	detection	NN
cord-306424-gf0bglm0	8	12	and	and	CC
cord-306424-gf0bglm0	8	13	downstream	downstream	JJ
cord-306424-gf0bglm0	8	14	signaling	signaling	NN
cord-306424-gf0bglm0	8	15	,	,	,
cord-306424-gf0bglm0	8	16	including	include	VBG
cord-306424-gf0bglm0	8	17	isolation	isolation	NN
cord-306424-gf0bglm0	8	18	of	of	IN
cord-306424-gf0bglm0	8	19	viral	viral	JJ
cord-306424-gf0bglm0	8	20	RNA	RNA	NNP
cord-306424-gf0bglm0	8	21	replication	replication	NN
cord-306424-gf0bglm0	8	22	in	in	IN
cord-306424-gf0bglm0	8	23	membranous	membranous	JJ
cord-306424-gf0bglm0	8	24	viral	viral	JJ
cord-306424-gf0bglm0	8	25	replication	replication	NN
cord-306424-gf0bglm0	8	26	organelles	organelle	NNS
cord-306424-gf0bglm0	8	27	(	(	-LRB-
cord-306424-gf0bglm0	8	28	ROs	ROs	NNP
cord-306424-gf0bglm0	8	29	)	)	-RRB-
cord-306424-gf0bglm0	8	30	.	.	.
cord-306424-gf0bglm0	9	1	These	these	DT
cord-306424-gf0bglm0	9	2	structures	structure	NNS
cord-306424-gf0bglm0	9	3	therefore	therefore	RB
cord-306424-gf0bglm0	9	4	play	play	VBP
cord-306424-gf0bglm0	9	5	a	a	DT
cord-306424-gf0bglm0	9	6	central	central	JJ
cord-306424-gf0bglm0	9	7	role	role	NN
cord-306424-gf0bglm0	9	8	in	in	IN
cord-306424-gf0bglm0	9	9	infection	infection	NN
cord-306424-gf0bglm0	9	10	,	,	,
cord-306424-gf0bglm0	9	11	and	and	CC
cord-306424-gf0bglm0	9	12	consequently	consequently	RB
cord-306424-gf0bglm0	9	13	,	,	,
cord-306424-gf0bglm0	9	14	loss	loss	NN
cord-306424-gf0bglm0	9	15	of	of	IN
cord-306424-gf0bglm0	9	16	RO	ro	NN
cord-306424-gf0bglm0	9	17	integrity	integrity	NN
cord-306424-gf0bglm0	9	18	might	may	MD
cord-306424-gf0bglm0	9	19	simultaneously	simultaneously	RB
cord-306424-gf0bglm0	9	20	result	result	VB
cord-306424-gf0bglm0	9	21	in	in	IN
cord-306424-gf0bglm0	9	22	impaired	impaired	JJ
cord-306424-gf0bglm0	9	23	viral	viral	JJ
cord-306424-gf0bglm0	9	24	replication	replication	NN
cord-306424-gf0bglm0	9	25	and	and	CC
cord-306424-gf0bglm0	9	26	enhanced	enhance	VBN
cord-306424-gf0bglm0	9	27	antiviral	antiviral	JJ
cord-306424-gf0bglm0	9	28	signaling	signaling	NN
cord-306424-gf0bglm0	9	29	.	.	.
cord-306424-gf0bglm0	10	1	This	this	DT
cord-306424-gf0bglm0	10	2	review	review	NN
cord-306424-gf0bglm0	10	3	summarizes	summarize	VBZ
cord-306424-gf0bglm0	10	4	the	the	DT
cord-306424-gf0bglm0	10	5	first	first	JJ
cord-306424-gf0bglm0	10	6	indications	indication	NNS
cord-306424-gf0bglm0	10	7	that	that	IN
cord-306424-gf0bglm0	10	8	the	the	DT
cord-306424-gf0bglm0	10	9	innate	innate	JJ
cord-306424-gf0bglm0	10	10	immune	immune	JJ
cord-306424-gf0bglm0	10	11	system	system	NN
cord-306424-gf0bglm0	10	12	indeed	indeed	RB
cord-306424-gf0bglm0	10	13	has	have	VBZ
cord-306424-gf0bglm0	10	14	tools	tool	NNS
cord-306424-gf0bglm0	10	15	to	to	TO
cord-306424-gf0bglm0	10	16	disrupt	disrupt	VB
cord-306424-gf0bglm0	10	17	viral	viral	JJ
cord-306424-gf0bglm0	10	18	ROs	ro	NNS
cord-306424-gf0bglm0	10	19	and	and	CC
cord-306424-gf0bglm0	10	20	other	other	JJ
cord-306424-gf0bglm0	10	21	non-	non-	DT
cord-306424-gf0bglm0	10	22	or	or	CC
cord-306424-gf0bglm0	10	23	aberrant	aberrant	JJ
cord-306424-gf0bglm0	10	24	-	-	HYPH
cord-306424-gf0bglm0	10	25	self	self	NN
cord-306424-gf0bglm0	10	26	membrane	membrane	NN
cord-306424-gf0bglm0	10	27	structures	structure	NNS
cord-306424-gf0bglm0	10	28	,	,	,
cord-306424-gf0bglm0	10	29	and	and	CC
cord-306424-gf0bglm0	10	30	may	may	MD
cord-306424-gf0bglm0	10	31	do	do	VB
cord-306424-gf0bglm0	10	32	this	this	DT
cord-306424-gf0bglm0	10	33	by	by	IN
cord-306424-gf0bglm0	10	34	marking	mark	VBG
cord-306424-gf0bglm0	10	35	these	these	DT
cord-306424-gf0bglm0	10	36	membranes	membrane	NNS
cord-306424-gf0bglm0	10	37	with	with	IN
cord-306424-gf0bglm0	10	38	proteins	protein	NNS
cord-306424-gf0bglm0	10	39	such	such	JJ
cord-306424-gf0bglm0	10	40	as	as	IN
cord-306424-gf0bglm0	10	41	microtubule	microtubule	NN
cord-306424-gf0bglm0	10	42	-	-	HYPH
cord-306424-gf0bglm0	10	43	associated	associate	VBN
cord-306424-gf0bglm0	10	44	protein	protein	NN
cord-306424-gf0bglm0	10	45	1A/1B	1a/1b	CD
cord-306424-gf0bglm0	10	46	-	-	HYPH
cord-306424-gf0bglm0	10	47	light	light	NN
cord-306424-gf0bglm0	10	48	chain	chain	NN
cord-306424-gf0bglm0	10	49	3	3	CD
cord-306424-gf0bglm0	11	1	(	(	-LRB-
cord-306424-gf0bglm0	11	2	LC3	LC3	NNP
cord-306424-gf0bglm0	11	3	)	)	-RRB-
cord-306424-gf0bglm0	11	4	and	and	CC
cord-306424-gf0bglm0	11	5	ubiquitin	ubiquitin	NN
cord-306424-gf0bglm0	11	6	,	,	,
cord-306424-gf0bglm0	11	7	resulting	result	VBG
cord-306424-gf0bglm0	11	8	in	in	IN
cord-306424-gf0bglm0	11	9	the	the	DT
cord-306424-gf0bglm0	11	10	recruitment	recruitment	NN
cord-306424-gf0bglm0	11	11	of	of	IN
cord-306424-gf0bglm0	11	12	IFN	IFN	NNP
cord-306424-gf0bglm0	11	13	-	-	HYPH
cord-306424-gf0bglm0	11	14	inducible	inducible	JJ
cord-306424-gf0bglm0	11	15	GTPases	gtpase	NNS
cord-306424-gf0bglm0	11	16	.	.	.
cord-306424-gf0bglm0	12	1	Further	further	JJ
cord-306424-gf0bglm0	12	2	studies	study	NNS
cord-306424-gf0bglm0	12	3	should	should	MD
cord-306424-gf0bglm0	12	4	evaluate	evaluate	VB
cord-306424-gf0bglm0	12	5	whether	whether	IN
cord-306424-gf0bglm0	12	6	this	this	DT
cord-306424-gf0bglm0	12	7	process	process	NN
cord-306424-gf0bglm0	12	8	forms	form	VBZ
cord-306424-gf0bglm0	12	9	a	a	DT
cord-306424-gf0bglm0	12	10	general	general	JJ
cord-306424-gf0bglm0	12	11	effector	effector	NN
cord-306424-gf0bglm0	12	12	mechanism	mechanism	NN
cord-306424-gf0bglm0	12	13	in	in	IN
cord-306424-gf0bglm0	12	14	+	+	SYM
cord-306424-gf0bglm0	12	15	RNA	RNA	NNP
cord-306424-gf0bglm0	12	16	virus	virus	NN
cord-306424-gf0bglm0	12	17	infection	infection	NN
cord-306424-gf0bglm0	12	18	,	,	,
cord-306424-gf0bglm0	12	19	thereby	thereby	RB
cord-306424-gf0bglm0	12	20	creating	create	VBG
cord-306424-gf0bglm0	12	21	the	the	DT
cord-306424-gf0bglm0	12	22	opportunity	opportunity	NN
cord-306424-gf0bglm0	12	23	for	for	IN
cord-306424-gf0bglm0	12	24	development	development	NN
cord-306424-gf0bglm0	12	25	of	of	IN
cord-306424-gf0bglm0	12	26	novel	novel	JJ
cord-306424-gf0bglm0	12	27	antiviral	antiviral	JJ
cord-306424-gf0bglm0	12	28	therapies	therapy	NNS
cord-306424-gf0bglm0	12	29	.	.	.
cord-306424-gf0bglm0	13	1	The	the	DT
cord-306424-gf0bglm0	13	2	innate	innate	JJ
cord-306424-gf0bglm0	13	3	immune	immune	JJ
cord-306424-gf0bglm0	13	4	system	system	NN
cord-306424-gf0bglm0	13	5	forms	form	VBZ
cord-306424-gf0bglm0	13	6	the	the	DT
cord-306424-gf0bglm0	13	7	first	first	JJ
cord-306424-gf0bglm0	13	8	line	line	NN
cord-306424-gf0bglm0	13	9	of	of	IN
cord-306424-gf0bglm0	13	10	defense	defense	NN
cord-306424-gf0bglm0	13	11	against	against	IN
cord-306424-gf0bglm0	13	12	pathogens	pathogen	NNS
cord-306424-gf0bglm0	13	13	and	and	CC
cord-306424-gf0bglm0	13	14	its	-PRON-	PRP$
cord-306424-gf0bglm0	13	15	initial	initial	JJ
cord-306424-gf0bglm0	13	16	function	function	NN
cord-306424-gf0bglm0	13	17	is	be	VBZ
cord-306424-gf0bglm0	13	18	to	to	TO
cord-306424-gf0bglm0	13	19	recognize	recognize	VB
cord-306424-gf0bglm0	13	20	pathogenassociated	pathogenassociate	VBN
cord-306424-gf0bglm0	13	21	molecular	molecular	JJ
cord-306424-gf0bglm0	13	22	patterns	pattern	NNS
cord-306424-gf0bglm0	13	23	(	(	-LRB-
cord-306424-gf0bglm0	13	24	PAMPs	pamp	NNS
cord-306424-gf0bglm0	13	25	)	)	-RRB-
cord-306424-gf0bglm0	13	26	[	[	-LRB-
cord-306424-gf0bglm0	13	27	1	1	CD
cord-306424-gf0bglm0	13	28	]	]	-RRB-
cord-306424-gf0bglm0	13	29	,	,	,
cord-306424-gf0bglm0	13	30	which	which	WDT
cord-306424-gf0bglm0	13	31	ultimately	ultimately	RB
cord-306424-gf0bglm0	13	32	leads	lead	VBZ
cord-306424-gf0bglm0	13	33	to	to	IN
cord-306424-gf0bglm0	13	34	induction	induction	NN
cord-306424-gf0bglm0	13	35	of	of	IN
cord-306424-gf0bglm0	13	36	the	the	DT
cord-306424-gf0bglm0	13	37	antiviral	antiviral	JJ
cord-306424-gf0bglm0	13	38	state	state	NN
cord-306424-gf0bglm0	13	39	that	that	WDT
cord-306424-gf0bglm0	13	40	effectively	effectively	RB
cord-306424-gf0bglm0	13	41	hampers	hamper	VBZ
cord-306424-gf0bglm0	13	42	spread	spread	NN
cord-306424-gf0bglm0	13	43	of	of	IN
cord-306424-gf0bglm0	13	44	the	the	DT
cord-306424-gf0bglm0	13	45	infection	infection	NN
cord-306424-gf0bglm0	13	46	.	.	.
cord-306424-gf0bglm0	14	1	The	the	DT
cord-306424-gf0bglm0	14	2	adaptive	adaptive	JJ
cord-306424-gf0bglm0	14	3	immune	immune	JJ
cord-306424-gf0bglm0	14	4	system	system	NN
cord-306424-gf0bglm0	14	5	then	then	RB
cord-306424-gf0bglm0	14	6	kicks	kick	VBZ
cord-306424-gf0bglm0	14	7	in	in	RP
cord-306424-gf0bglm0	14	8	to	to	IN
cord-306424-gf0bglm0	14	9	(	(	-LRB-
cord-306424-gf0bglm0	14	10	in	in	IN
cord-306424-gf0bglm0	14	11	most	most	JJS
cord-306424-gf0bglm0	14	12	cases	case	NNS
cord-306424-gf0bglm0	14	13	)	)	-RRB-
cord-306424-gf0bglm0	14	14	fully	fully	RB
cord-306424-gf0bglm0	14	15	clear	clear	JJ
cord-306424-gf0bglm0	14	16	the	the	DT
cord-306424-gf0bglm0	14	17	virus	virus	NN
cord-306424-gf0bglm0	14	18	and	and	CC
cord-306424-gf0bglm0	14	19	build	build	VB
cord-306424-gf0bglm0	14	20	up	up	RP
cord-306424-gf0bglm0	14	21	memory	memory	NN
cord-306424-gf0bglm0	14	22	.	.	.
cord-306424-gf0bglm0	15	1	Viral	Viral	NNP
cord-306424-gf0bglm0	15	2	RNA	RNA	NNP
cord-306424-gf0bglm0	15	3	is	be	VBZ
cord-306424-gf0bglm0	15	4	a	a	DT
cord-306424-gf0bglm0	15	5	very	very	RB
cord-306424-gf0bglm0	15	6	potent	potent	JJ
cord-306424-gf0bglm0	15	7	inducer	inducer	NN
cord-306424-gf0bglm0	15	8	of	of	IN
cord-306424-gf0bglm0	15	9	innate	innate	JJ
cord-306424-gf0bglm0	15	10	antiviral	antiviral	JJ
cord-306424-gf0bglm0	15	11	signaling	signal	VBG
cord-306424-gf0bglm0	15	12	[	[	-LRB-
cord-306424-gf0bglm0	15	13	2	2	CD
cord-306424-gf0bglm0	15	14	,	,	,
cord-306424-gf0bglm0	15	15	3	3	CD
cord-306424-gf0bglm0	15	16	]	]	-RRB-
cord-306424-gf0bglm0	15	17	.	.	.
cord-306424-gf0bglm0	16	1	Therefore	therefore	RB
cord-306424-gf0bglm0	16	2	,	,	,
cord-306424-gf0bglm0	16	3	detection	detection	NN
cord-306424-gf0bglm0	16	4	of	of	IN
cord-306424-gf0bglm0	16	5	viral	viral	JJ
cord-306424-gf0bglm0	16	6	RNA	RNA	NNP
cord-306424-gf0bglm0	16	7	and	and	CC
cord-306424-gf0bglm0	16	8	the	the	DT
cord-306424-gf0bglm0	16	9	subsequent	subsequent	JJ
cord-306424-gf0bglm0	16	10	induction	induction	NN
cord-306424-gf0bglm0	16	11	of	of	IN
cord-306424-gf0bglm0	16	12	antiviral	antiviral	JJ
cord-306424-gf0bglm0	16	13	effector	effector	NN
cord-306424-gf0bglm0	16	14	mechanisms	mechanism	NNS
cord-306424-gf0bglm0	16	15	play	play	VBP
cord-306424-gf0bglm0	16	16	an	an	DT
cord-306424-gf0bglm0	16	17	important	important	JJ
cord-306424-gf0bglm0	16	18	part	part	NN
cord-306424-gf0bglm0	16	19	in	in	IN
cord-306424-gf0bglm0	16	20	the	the	DT
cord-306424-gf0bglm0	16	21	onset	onset	NN
cord-306424-gf0bglm0	16	22	of	of	IN
cord-306424-gf0bglm0	16	23	an	an	DT
cord-306424-gf0bglm0	16	24	antiviral	antiviral	JJ
cord-306424-gf0bglm0	16	25	state	state	NN
cord-306424-gf0bglm0	16	26	in	in	IN
cord-306424-gf0bglm0	16	27	the	the	DT
cord-306424-gf0bglm0	16	28	context	context	NN
cord-306424-gf0bglm0	16	29	of	of	IN
cord-306424-gf0bglm0	16	30	RNA	RNA	NNP
cord-306424-gf0bglm0	16	31	virus	virus	NN
cord-306424-gf0bglm0	16	32	infections	infection	NNS
cord-306424-gf0bglm0	16	33	.	.	.
cord-306424-gf0bglm0	17	1	The	the	DT
cord-306424-gf0bglm0	17	2	study	study	NN
cord-306424-gf0bglm0	17	3	of	of	IN
cord-306424-gf0bglm0	17	4	PAMP	PAMP	NNP
cord-306424-gf0bglm0	17	5	recognition	recognition	NN
cord-306424-gf0bglm0	17	6	and	and	CC
cord-306424-gf0bglm0	17	7	signaling	signal	VBG
cord-306424-gf0bglm0	17	8	by	by	IN
cord-306424-gf0bglm0	17	9	cytosolic	cytosolic	JJ
cord-306424-gf0bglm0	17	10	and	and	CC
cord-306424-gf0bglm0	17	11	membrane	membrane	NN
cord-306424-gf0bglm0	17	12	bound	bind	VBN
cord-306424-gf0bglm0	17	13	sensors	sensor	NNS
cord-306424-gf0bglm0	17	14	has	have	VBZ
cord-306424-gf0bglm0	17	15	intensified	intensify	VBN
cord-306424-gf0bglm0	17	16	tremendously	tremendously	RB
cord-306424-gf0bglm0	17	17	in	in	IN
cord-306424-gf0bglm0	17	18	the	the	DT
cord-306424-gf0bglm0	17	19	last	last	JJ
cord-306424-gf0bglm0	17	20	decade	decade	NN
cord-306424-gf0bglm0	17	21	.	.	.
cord-306424-gf0bglm0	18	1	Several	several	JJ
cord-306424-gf0bglm0	18	2	comprehensive	comprehensive	JJ
cord-306424-gf0bglm0	18	3	reviews	review	NNS
cord-306424-gf0bglm0	18	4	on	on	IN
cord-306424-gf0bglm0	18	5	this	this	DT
cord-306424-gf0bglm0	18	6	subject	subject	NN
cord-306424-gf0bglm0	18	7	have	have	VBP
cord-306424-gf0bglm0	18	8	been	be	VBN
cord-306424-gf0bglm0	18	9	published	publish	VBN
cord-306424-gf0bglm0	18	10	lately	lately	RB
cord-306424-gf0bglm0	18	11	[	[	-LRB-
cord-306424-gf0bglm0	18	12	4	4	CD
cord-306424-gf0bglm0	18	13	,	,	,
cord-306424-gf0bglm0	18	14	5	5	CD
cord-306424-gf0bglm0	18	15	]	]	-RRB-
cord-306424-gf0bglm0	18	16	.	.	.
cord-306424-gf0bglm0	19	1	Additionally	additionally	RB
cord-306424-gf0bglm0	19	2	,	,	,
cord-306424-gf0bglm0	19	3	investigation	investigation	NN
cord-306424-gf0bglm0	19	4	of	of	IN
cord-306424-gf0bglm0	19	5	the	the	DT
cord-306424-gf0bglm0	19	6	involvement	involvement	NN
cord-306424-gf0bglm0	19	7	of	of	IN
cord-306424-gf0bglm0	19	8	intracellular	intracellular	JJ
cord-306424-gf0bglm0	19	9	organelle	organelle	NN
cord-306424-gf0bglm0	19	10	membranes	membrane	NNS
cord-306424-gf0bglm0	19	11	of	of	IN
cord-306424-gf0bglm0	19	12	mitochondria	mitochondrion	NNS
cord-306424-gf0bglm0	19	13	,	,	,
cord-306424-gf0bglm0	19	14	ER	ER	NNP
cord-306424-gf0bglm0	19	15	,	,	,
cord-306424-gf0bglm0	19	16	and	and	CC
cord-306424-gf0bglm0	19	17	peroxisomes	peroxisome	NNS
cord-306424-gf0bglm0	19	18	and	and	CC
cord-306424-gf0bglm0	19	19	their	-PRON-	PRP$
cord-306424-gf0bglm0	19	20	mutual	mutual	JJ
cord-306424-gf0bglm0	19	21	interactions	interaction	NNS
cord-306424-gf0bglm0	19	22	indicated	indicate	VBD
cord-306424-gf0bglm0	19	23	that	that	IN
cord-306424-gf0bglm0	19	24	these	these	DT
cord-306424-gf0bglm0	19	25	are	be	VBP
cord-306424-gf0bglm0	19	26	important	important	JJ
cord-306424-gf0bglm0	19	27	signaling	signal	VBG
cord-306424-gf0bglm0	19	28	platforms	platform	NNS
cord-306424-gf0bglm0	19	29	in	in	IN
cord-306424-gf0bglm0	19	30	innate	innate	JJ
cord-306424-gf0bglm0	19	31	immunity	immunity	NN
cord-306424-gf0bglm0	19	32	[	[	-LRB-
cord-306424-gf0bglm0	19	33	6	6	CD
cord-306424-gf0bglm0	19	34	,	,	,
cord-306424-gf0bglm0	19	35	7	7	CD
cord-306424-gf0bglm0	19	36	]	]	-RRB-
cord-306424-gf0bglm0	19	37	.	.	.
cord-306424-gf0bglm0	20	1	Together	together	RB
cord-306424-gf0bglm0	20	2	,	,	,
cord-306424-gf0bglm0	20	3	this	this	DT
cord-306424-gf0bglm0	20	4	has	have	VBZ
cord-306424-gf0bglm0	20	5	resulted	result	VBN
cord-306424-gf0bglm0	20	6	in	in	IN
cord-306424-gf0bglm0	20	7	a	a	DT
cord-306424-gf0bglm0	20	8	better	well	JJR
cord-306424-gf0bglm0	20	9	understanding	understanding	NN
cord-306424-gf0bglm0	20	10	of	of	IN
cord-306424-gf0bglm0	20	11	the	the	DT
cord-306424-gf0bglm0	20	12	details	detail	NNS
cord-306424-gf0bglm0	20	13	of	of	IN
cord-306424-gf0bglm0	20	14	innate	innate	JJ
cord-306424-gf0bglm0	20	15	immune	immune	JJ
cord-306424-gf0bglm0	20	16	responses	response	NNS
cord-306424-gf0bglm0	20	17	that	that	WDT
cord-306424-gf0bglm0	20	18	target	target	VBP
cord-306424-gf0bglm0	20	19	RNA	rna	NN
cord-306424-gf0bglm0	20	20	viruses	virus	NNS
cord-306424-gf0bglm0	20	21	.	.	.
cord-306424-gf0bglm0	21	1	In	in	IN
cord-306424-gf0bglm0	21	2	this	this	DT
cord-306424-gf0bglm0	21	3	review	review	NN
cord-306424-gf0bglm0	21	4	,	,	,
cord-306424-gf0bglm0	21	5	we	-PRON-	PRP
cord-306424-gf0bglm0	21	6	will	will	MD
cord-306424-gf0bglm0	21	7	focus	focus	VB
cord-306424-gf0bglm0	21	8	on	on	IN
cord-306424-gf0bglm0	21	9	the	the	DT
cord-306424-gf0bglm0	21	10	interaction	interaction	NN
cord-306424-gf0bglm0	21	11	of	of	IN
cord-306424-gf0bglm0	21	12	the	the	DT
cord-306424-gf0bglm0	21	13	innate	innate	JJ
cord-306424-gf0bglm0	21	14	immune	immune	JJ
cord-306424-gf0bglm0	21	15	system	system	NN
cord-306424-gf0bglm0	21	16	with	with	IN
cord-306424-gf0bglm0	21	17	viruses	virus	NNS
cord-306424-gf0bglm0	21	18	that	that	WDT
cord-306424-gf0bglm0	21	19	have	have	VBP
cord-306424-gf0bglm0	21	20	a	a	DT
cord-306424-gf0bglm0	21	21	positive	positive	JJ
cord-306424-gf0bglm0	21	22	-	-	HYPH
cord-306424-gf0bglm0	21	23	strand	strand	NN
cord-306424-gf0bglm0	21	24	RNA	RNA	NNP
cord-306424-gf0bglm0	21	25	(	(	-LRB-
cord-306424-gf0bglm0	21	26	+	+	CC
cord-306424-gf0bglm0	21	27	RNA	RNA	NNP
cord-306424-gf0bglm0	21	28	)	)	-RRB-
cord-306424-gf0bglm0	21	29	genome	genome	NN
cord-306424-gf0bglm0	21	30	.	.	.
cord-306424-gf0bglm0	22	1	In	in	IN
cord-306424-gf0bglm0	22	2	response	response	NN
cord-306424-gf0bglm0	22	3	to	to	TO
cord-306424-gf0bglm0	22	4	innate	innate	VB
cord-306424-gf0bglm0	22	5	immune	immune	JJ
cord-306424-gf0bglm0	22	6	reactions	reaction	NNS
cord-306424-gf0bglm0	22	7	,	,	,
cord-306424-gf0bglm0	22	8	virtually	virtually	RB
cord-306424-gf0bglm0	22	9	all	all	DT
cord-306424-gf0bglm0	22	10	+	+	-RRB-
cord-306424-gf0bglm0	22	11	RNA	rna	NN
cord-306424-gf0bglm0	22	12	viruses	virus	NNS
cord-306424-gf0bglm0	22	13	interfere	interfere	VBP
cord-306424-gf0bglm0	22	14	to	to	TO
cord-306424-gf0bglm0	22	15	delay	delay	VB
cord-306424-gf0bglm0	22	16	antiviral	antiviral	JJ
cord-306424-gf0bglm0	22	17	innate	innate	JJ
cord-306424-gf0bglm0	22	18	immune	immune	JJ
cord-306424-gf0bglm0	22	19	signaling	signaling	NN
cord-306424-gf0bglm0	22	20	in	in	IN
cord-306424-gf0bglm0	22	21	several	several	JJ
cord-306424-gf0bglm0	22	22	ways	way	NNS
cord-306424-gf0bglm0	22	23	[	[	-LRB-
cord-306424-gf0bglm0	22	24	1	1	CD
cord-306424-gf0bglm0	22	25	,	,	,
cord-306424-gf0bglm0	22	26	8	8	CD
cord-306424-gf0bglm0	22	27	,	,	,
cord-306424-gf0bglm0	22	28	9	9	CD
cord-306424-gf0bglm0	22	29	]	]	-RRB-
cord-306424-gf0bglm0	22	30	.	.	.
cord-306424-gf0bglm0	23	1	A	a	DT
cord-306424-gf0bglm0	23	2	key	key	JJ
cord-306424-gf0bglm0	23	3	feature	feature	NN
cord-306424-gf0bglm0	23	4	of	of	IN
cord-306424-gf0bglm0	23	5	immune	immune	JJ
cord-306424-gf0bglm0	23	6	evasion	evasion	NN
cord-306424-gf0bglm0	23	7	by	by	IN
cord-306424-gf0bglm0	23	8	+	+	CC
cord-306424-gf0bglm0	23	9	RNA	RNA	NNP
cord-306424-gf0bglm0	23	10	viruses	virus	NNS
cord-306424-gf0bglm0	23	11	,	,	,
cord-306424-gf0bglm0	23	12	and	and	CC
cord-306424-gf0bglm0	23	13	simultaneously	simultaneously	RB
cord-306424-gf0bglm0	23	14	the	the	DT
cord-306424-gf0bglm0	23	15	hallmark	hallmark	NN
cord-306424-gf0bglm0	23	16	of	of	IN
cord-306424-gf0bglm0	23	17	+	+	SYM
cord-306424-gf0bglm0	23	18	RNA	RNA	NNP
cord-306424-gf0bglm0	23	19	virus	virus	NN
cord-306424-gf0bglm0	23	20	infection	infection	NN
cord-306424-gf0bglm0	23	21	,	,	,
cord-306424-gf0bglm0	23	22	is	be	VBZ
cord-306424-gf0bglm0	23	23	rearrangement	rearrangement	NN
cord-306424-gf0bglm0	23	24	of	of	IN
cord-306424-gf0bglm0	23	25	host	host	NN
cord-306424-gf0bglm0	23	26	membranes	membrane	NNS
cord-306424-gf0bglm0	23	27	into	into	IN
cord-306424-gf0bglm0	23	28	viral	viral	JJ
cord-306424-gf0bglm0	23	29	replication	replication	NN
cord-306424-gf0bglm0	23	30	organelles	organelle	NNS
cord-306424-gf0bglm0	23	31	(	(	-LRB-
cord-306424-gf0bglm0	23	32	ROs	ROs	NNP
cord-306424-gf0bglm0	23	33	)	)	-RRB-
cord-306424-gf0bglm0	23	34	.	.	.
cord-306424-gf0bglm0	24	1	As	as	IN
cord-306424-gf0bglm0	24	2	these	these	DT
cord-306424-gf0bglm0	24	3	structures	structure	NNS
cord-306424-gf0bglm0	24	4	are	be	VBP
cord-306424-gf0bglm0	24	5	thought	think	VBN
cord-306424-gf0bglm0	24	6	to	to	TO
cord-306424-gf0bglm0	24	7	shield	shield	VB
cord-306424-gf0bglm0	24	8	viral	viral	JJ
cord-306424-gf0bglm0	24	9	RNA	RNA	NNP
cord-306424-gf0bglm0	24	10	from	from	IN
cord-306424-gf0bglm0	24	11	the	the	DT
cord-306424-gf0bglm0	24	12	host	host	NN
cord-306424-gf0bglm0	24	13	innate	innate	JJ
cord-306424-gf0bglm0	24	14	immune	immune	JJ
cord-306424-gf0bglm0	24	15	system	system	NN
cord-306424-gf0bglm0	24	16	and	and	CC
cord-306424-gf0bglm0	24	17	additionally	additionally	RB
cord-306424-gf0bglm0	24	18	seem	seem	VBP
cord-306424-gf0bglm0	24	19	to	to	TO
cord-306424-gf0bglm0	24	20	play	play	VB
cord-306424-gf0bglm0	24	21	a	a	DT
cord-306424-gf0bglm0	24	22	fundamental	fundamental	JJ
cord-306424-gf0bglm0	24	23	role	role	NN
cord-306424-gf0bglm0	24	24	in	in	IN
cord-306424-gf0bglm0	24	25	viral	viral	JJ
cord-306424-gf0bglm0	24	26	RNA	RNA	NNP
cord-306424-gf0bglm0	24	27	replication	replication	NN
cord-306424-gf0bglm0	24	28	,	,	,
cord-306424-gf0bglm0	24	29	ROs	ROs	NNP
cord-306424-gf0bglm0	24	30	in	in	IN
cord-306424-gf0bglm0	24	31	this	this	DT
cord-306424-gf0bglm0	24	32	sense	sense	NN
cord-306424-gf0bglm0	24	33	seem	seem	VBP
cord-306424-gf0bglm0	24	34	to	to	TO
cord-306424-gf0bglm0	24	35	have	have	VB
cord-306424-gf0bglm0	24	36	a	a	DT
cord-306424-gf0bglm0	24	37	central	central	JJ
cord-306424-gf0bglm0	24	38	and	and	CC
cord-306424-gf0bglm0	24	39	dual	dual	JJ
cord-306424-gf0bglm0	24	40	function	function	NN
cord-306424-gf0bglm0	24	41	in	in	IN
cord-306424-gf0bglm0	24	42	viral	viral	JJ
cord-306424-gf0bglm0	24	43	replication	replication	NN
cord-306424-gf0bglm0	24	44	[	[	-LRB-
cord-306424-gf0bglm0	24	45	10	10	CD
cord-306424-gf0bglm0	24	46	]	]	-RRB-
cord-306424-gf0bglm0	24	47	[	[	-LRB-
cord-306424-gf0bglm0	24	48	11	11	CD
cord-306424-gf0bglm0	24	49	]	]	-RRB-
cord-306424-gf0bglm0	24	50	[	[	-LRB-
cord-306424-gf0bglm0	24	51	12	12	CD
cord-306424-gf0bglm0	24	52	]	]	-RRB-
cord-306424-gf0bglm0	24	53	[	[	-LRB-
cord-306424-gf0bglm0	24	54	13	13	CD
cord-306424-gf0bglm0	24	55	]	]	-RRB-
cord-306424-gf0bglm0	24	56	[	[	-LRB-
cord-306424-gf0bglm0	24	57	14	14	CD
cord-306424-gf0bglm0	24	58	]	]	-RRB-
cord-306424-gf0bglm0	24	59	.	.	.
cord-306424-gf0bglm0	25	1	Therefore	therefore	RB
cord-306424-gf0bglm0	25	2	,	,	,
cord-306424-gf0bglm0	25	3	disrupting	disrupt	VBG
cord-306424-gf0bglm0	25	4	integrity	integrity	NN
cord-306424-gf0bglm0	25	5	of	of	IN
cord-306424-gf0bglm0	25	6	ROs	ROs	NNP
cord-306424-gf0bglm0	25	7	might	may	MD
cord-306424-gf0bglm0	25	8	simultaneously	simultaneously	RB
cord-306424-gf0bglm0	25	9	result	result	VB
cord-306424-gf0bglm0	25	10	in	in	IN
cord-306424-gf0bglm0	25	11	impaired	impaired	JJ
cord-306424-gf0bglm0	25	12	viral	viral	JJ
cord-306424-gf0bglm0	25	13	replication	replication	NN
cord-306424-gf0bglm0	25	14	and	and	CC
cord-306424-gf0bglm0	25	15	enhanced	enhance	VBN
cord-306424-gf0bglm0	25	16	antiviral	antiviral	JJ
cord-306424-gf0bglm0	25	17	immune	immune	NN
cord-306424-gf0bglm0	25	18	signaling	signaling	NN
cord-306424-gf0bglm0	25	19	,	,	,
cord-306424-gf0bglm0	25	20	which	which	WDT
cord-306424-gf0bglm0	25	21	would	would	MD
cord-306424-gf0bglm0	25	22	be	be	VB
cord-306424-gf0bglm0	25	23	a	a	DT
cord-306424-gf0bglm0	25	24	beneficial	beneficial	JJ
cord-306424-gf0bglm0	25	25	effect	effect	NN
cord-306424-gf0bglm0	25	26	from	from	IN
cord-306424-gf0bglm0	25	27	an	an	DT
cord-306424-gf0bglm0	25	28	antiviral	antiviral	JJ
cord-306424-gf0bglm0	25	29	immunity	immunity	NN
cord-306424-gf0bglm0	25	30	point	point	NN
cord-306424-gf0bglm0	25	31	-	-	HYPH
cord-306424-gf0bglm0	25	32	of	of	IN
cord-306424-gf0bglm0	25	33	-	-	HYPH
cord-306424-gf0bglm0	25	34	view	view	NN
cord-306424-gf0bglm0	25	35	.	.	.
cord-306424-gf0bglm0	26	1	However	however	RB
cord-306424-gf0bglm0	26	2	,	,	,
cord-306424-gf0bglm0	26	3	whether	whether	IN
cord-306424-gf0bglm0	26	4	host	host	NN
cord-306424-gf0bglm0	26	5	cells	cell	NNS
cord-306424-gf0bglm0	26	6	possess	possess	VBP
cord-306424-gf0bglm0	26	7	effector	effector	JJ
cord-306424-gf0bglm0	26	8	mechanisms	mechanism	NNS
cord-306424-gf0bglm0	26	9	to	to	TO
cord-306424-gf0bglm0	26	10	disrupt	disrupt	VB
cord-306424-gf0bglm0	26	11	+	+	CC
cord-306424-gf0bglm0	26	12	RNA	RNA	NNP
cord-306424-gf0bglm0	26	13	virus	virus	NN
cord-306424-gf0bglm0	26	14	ROs	ROs	NNP
cord-306424-gf0bglm0	26	15	has	have	VBZ
cord-306424-gf0bglm0	26	16	hardly	hardly	RB
cord-306424-gf0bglm0	26	17	been	be	VBN
cord-306424-gf0bglm0	26	18	investigated	investigate	VBN
cord-306424-gf0bglm0	26	19	yet	yet	RB
cord-306424-gf0bglm0	26	20	,	,	,
cord-306424-gf0bglm0	26	21	and	and	CC
cord-306424-gf0bglm0	26	22	only	only	RB
cord-306424-gf0bglm0	26	23	quite	quite	RB
cord-306424-gf0bglm0	26	24	recently	recently	RB
cord-306424-gf0bglm0	26	25	some	some	DT
cord-306424-gf0bglm0	26	26	studies	study	NNS
cord-306424-gf0bglm0	26	27	have	have	VBP
cord-306424-gf0bglm0	26	28	shed	shed	VBN
cord-306424-gf0bglm0	26	29	more	more	JJR
cord-306424-gf0bglm0	26	30	light	light	NN
cord-306424-gf0bglm0	26	31	on	on	IN
cord-306424-gf0bglm0	26	32	this	this	DT
cord-306424-gf0bglm0	26	33	,	,	,
cord-306424-gf0bglm0	26	34	which	which	WDT
cord-306424-gf0bglm0	26	35	will	will	MD
cord-306424-gf0bglm0	26	36	be	be	VB
cord-306424-gf0bglm0	26	37	the	the	DT
cord-306424-gf0bglm0	26	38	focus	focus	NN
cord-306424-gf0bglm0	26	39	of	of	IN
cord-306424-gf0bglm0	26	40	this	this	DT
cord-306424-gf0bglm0	26	41	review	review	NN
cord-306424-gf0bglm0	26	42	together	together	RB
cord-306424-gf0bglm0	26	43	with	with	IN
cord-306424-gf0bglm0	26	44	the	the	DT
cord-306424-gf0bglm0	26	45	body	body	NN
cord-306424-gf0bglm0	26	46	of	of	IN
cord-306424-gf0bglm0	26	47	literature	literature	NN
cord-306424-gf0bglm0	26	48	that	that	WDT
cord-306424-gf0bglm0	26	49	surrounds	surround	VBZ
cord-306424-gf0bglm0	26	50	it	-PRON-	PRP
cord-306424-gf0bglm0	26	51	.	.	.
cord-306424-gf0bglm0	27	1	Positive	positive	JJ
cord-306424-gf0bglm0	27	2	-	-	HYPH
cord-306424-gf0bglm0	27	3	strand	strand	NN
cord-306424-gf0bglm0	27	4	RNA	RNA	NNP
cord-306424-gf0bglm0	27	5	viruses	virus	NNS
cord-306424-gf0bglm0	27	6	have	have	VBP
cord-306424-gf0bglm0	27	7	caused	cause	VBN
cord-306424-gf0bglm0	27	8	multiple	multiple	JJ
cord-306424-gf0bglm0	27	9	outbreaks	outbreak	NNS
cord-306424-gf0bglm0	27	10	during	during	IN
cord-306424-gf0bglm0	27	11	the	the	DT
cord-306424-gf0bglm0	27	12	past	past	JJ
cord-306424-gf0bglm0	27	13	decade	decade	NN
cord-306424-gf0bglm0	27	14	:	:	:
cord-306424-gf0bglm0	27	15	severe	severe	JJ
cord-306424-gf0bglm0	27	16	acute	acute	JJ
cord-306424-gf0bglm0	27	17	respiratory	respiratory	JJ
cord-306424-gf0bglm0	27	18	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	27	19	(	(	-LRB-
cord-306424-gf0bglm0	27	20	SARS	SARS	NNP
cord-306424-gf0bglm0	27	21	-	-	HYPH
cord-306424-gf0bglm0	27	22	CoV	CoV	NNP
cord-306424-gf0bglm0	27	23	)	)	-RRB-
cord-306424-gf0bglm0	27	24	infected	infect	VBD
cord-306424-gf0bglm0	27	25	more	more	JJR
cord-306424-gf0bglm0	27	26	than	than	IN
cord-306424-gf0bglm0	27	27	8000	8000	CD
cord-306424-gf0bglm0	27	28	individuals	individual	NNS
cord-306424-gf0bglm0	27	29	in	in	IN
cord-306424-gf0bglm0	27	30	2003	2003	CD
cord-306424-gf0bglm0	27	31	of	of	IN
cord-306424-gf0bglm0	27	32	which	which	WDT
cord-306424-gf0bglm0	27	33	almost	almost	RB
cord-306424-gf0bglm0	27	34	800	800	CD
cord-306424-gf0bglm0	27	35	died	die	VBD
cord-306424-gf0bglm0	27	36	[	[	-LRB-
cord-306424-gf0bglm0	27	37	15	15	CD
cord-306424-gf0bglm0	27	38	]	]	-RRB-
cord-306424-gf0bglm0	27	39	.	.	.
cord-306424-gf0bglm0	28	1	Its	-PRON-	PRP$
cord-306424-gf0bglm0	28	2	close	close	JJ
cord-306424-gf0bglm0	28	3	relative	relative	JJ
cord-306424-gf0bglm0	28	4	Middle	Middle	NNP
cord-306424-gf0bglm0	28	5	East	East	NNP
cord-306424-gf0bglm0	28	6	respiratory	respiratory	JJ
cord-306424-gf0bglm0	28	7	syndrome	syndrome	NN
cord-306424-gf0bglm0	28	8	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	28	9	(	(	-LRB-
cord-306424-gf0bglm0	28	10	MERS	MERS	NNP
cord-306424-gf0bglm0	28	11	-	-	HYPH
cord-306424-gf0bglm0	28	12	CoV	CoV	NNP
cord-306424-gf0bglm0	28	13	)	)	-RRB-
cord-306424-gf0bglm0	28	14	emerged	emerge	VBD
cord-306424-gf0bglm0	28	15	in	in	IN
cord-306424-gf0bglm0	28	16	Saudi	Saudi	NNP
cord-306424-gf0bglm0	28	17	Arabia	Arabia	NNP
cord-306424-gf0bglm0	28	18	in	in	IN
cord-306424-gf0bglm0	28	19	2012	2012	CD
cord-306424-gf0bglm0	28	20	.	.	.
cord-306424-gf0bglm0	29	1	While	while	IN
cord-306424-gf0bglm0	29	2	SARS	SARS	NNP
cord-306424-gf0bglm0	29	3	-	-	HYPH
cord-306424-gf0bglm0	29	4	CoV	cov	NN
cord-306424-gf0bglm0	29	5	infections	infection	NNS
cord-306424-gf0bglm0	29	6	have	have	VBP
cord-306424-gf0bglm0	29	7	not	not	RB
cord-306424-gf0bglm0	29	8	been	be	VBN
cord-306424-gf0bglm0	29	9	reported	report	VBN
cord-306424-gf0bglm0	29	10	in	in	IN
cord-306424-gf0bglm0	29	11	humans	human	NNS
cord-306424-gf0bglm0	29	12	after	after	IN
cord-306424-gf0bglm0	29	13	2004	2004	CD
cord-306424-gf0bglm0	29	14	,	,	,
cord-306424-gf0bglm0	29	15	MERS	MERS	NNP
cord-306424-gf0bglm0	29	16	-	-	HYPH
cord-306424-gf0bglm0	29	17	CoV	CoV	NNP
cord-306424-gf0bglm0	29	18	currently	currently	RB
cord-306424-gf0bglm0	29	19	still	still	RB
cord-306424-gf0bglm0	29	20	regularly	regularly	RB
cord-306424-gf0bglm0	29	21	occurs	occur	VBZ
cord-306424-gf0bglm0	29	22	in	in	IN
cord-306424-gf0bglm0	29	23	dromedary	dromedary	NN
cord-306424-gf0bglm0	29	24	camels	camel	NNS
cord-306424-gf0bglm0	29	25	as	as	RB
cord-306424-gf0bglm0	29	26	well	well	RB
cord-306424-gf0bglm0	29	27	as	as	IN
cord-306424-gf0bglm0	29	28	in	in	IN
cord-306424-gf0bglm0	29	29	humans	human	NNS
cord-306424-gf0bglm0	29	30	,	,	,
cord-306424-gf0bglm0	29	31	and	and	CC
cord-306424-gf0bglm0	29	32	the	the	DT
cord-306424-gf0bglm0	29	33	virus	virus	NN
cord-306424-gf0bglm0	29	34	displays	display	VBZ
cord-306424-gf0bglm0	29	35	a	a	DT
cord-306424-gf0bglm0	29	36	lethality	lethality	NN
cord-306424-gf0bglm0	29	37	rate	rate	NN
cord-306424-gf0bglm0	29	38	of	of	IN
cord-306424-gf0bglm0	29	39	around	around	IN
cord-306424-gf0bglm0	29	40	35	35	CD
cord-306424-gf0bglm0	29	41	%	%	NN
cord-306424-gf0bglm0	29	42	in	in	IN
cord-306424-gf0bglm0	29	43	the	the	DT
cord-306424-gf0bglm0	29	44	latter	latter	JJ
cord-306424-gf0bglm0	29	45	[	[	-LRB-
cord-306424-gf0bglm0	29	46	16	16	CD
cord-306424-gf0bglm0	29	47	]	]	-RRB-
cord-306424-gf0bglm0	29	48	.	.	.
cord-306424-gf0bglm0	30	1	Zika	Zika	NNP
cord-306424-gf0bglm0	30	2	virus	virus	NN
cord-306424-gf0bglm0	30	3	,	,	,
cord-306424-gf0bglm0	30	4	which	which	WDT
cord-306424-gf0bglm0	30	5	received	receive	VBD
cord-306424-gf0bglm0	30	6	a	a	DT
cord-306424-gf0bglm0	30	7	lot	lot	NN
cord-306424-gf0bglm0	30	8	of	of	IN
cord-306424-gf0bglm0	30	9	societal	societal	JJ
cord-306424-gf0bglm0	30	10	attention	attention	NN
cord-306424-gf0bglm0	30	11	lately	lately	RB
cord-306424-gf0bglm0	30	12	,	,	,
cord-306424-gf0bglm0	30	13	is	be	VBZ
cord-306424-gf0bglm0	30	14	an	an	DT
cord-306424-gf0bglm0	30	15	example	example	NN
cord-306424-gf0bglm0	30	16	of	of	IN
cord-306424-gf0bglm0	30	17	a	a	DT
cord-306424-gf0bglm0	30	18	reemerged	reemerged	JJ
cord-306424-gf0bglm0	30	19	+	+	CC
cord-306424-gf0bglm0	30	20	RNA	RNA	NNP
cord-306424-gf0bglm0	30	21	virus	virus	NN
cord-306424-gf0bglm0	30	22	with	with	IN
cord-306424-gf0bglm0	30	23	significant	significant	JJ
cord-306424-gf0bglm0	30	24	impact	impact	NN
cord-306424-gf0bglm0	30	25	[	[	-LRB-
cord-306424-gf0bglm0	30	26	17	17	CD
cord-306424-gf0bglm0	30	27	]	]	-RRB-
cord-306424-gf0bglm0	30	28	.	.	.
cord-306424-gf0bglm0	31	1	These	these	DT
cord-306424-gf0bglm0	31	2	outbreaks	outbreak	NNS
cord-306424-gf0bglm0	31	3	,	,	,
cord-306424-gf0bglm0	31	4	and	and	CC
cord-306424-gf0bglm0	31	5	the	the	DT
cord-306424-gf0bglm0	31	6	lack	lack	NN
cord-306424-gf0bglm0	31	7	of	of	IN
cord-306424-gf0bglm0	31	8	tailored	tailor	VBN
cord-306424-gf0bglm0	31	9	antiviral	antiviral	JJ
cord-306424-gf0bglm0	31	10	strategies	strategy	NNS
cord-306424-gf0bglm0	31	11	against	against	IN
cord-306424-gf0bglm0	31	12	them	-PRON-	PRP
cord-306424-gf0bglm0	31	13	,	,	,
cord-306424-gf0bglm0	31	14	clearly	clearly	RB
cord-306424-gf0bglm0	31	15	illustrate	illustrate	VBP
cord-306424-gf0bglm0	31	16	the	the	DT
cord-306424-gf0bglm0	31	17	potential	potential	JJ
cord-306424-gf0bglm0	31	18	health	health	NN
cord-306424-gf0bglm0	31	19	risks	risk	NNS
cord-306424-gf0bglm0	31	20	associated	associate	VBN
cord-306424-gf0bglm0	31	21	with	with	IN
cord-306424-gf0bglm0	31	22	(	(	-LRB-
cord-306424-gf0bglm0	31	23	re-)emerging	re-)emerging	NNP
cord-306424-gf0bglm0	31	24	+	+	CC
cord-306424-gf0bglm0	31	25	RNA	RNA	NNP
cord-306424-gf0bglm0	31	26	viruses	virus	NNS
cord-306424-gf0bglm0	31	27	,	,	,
cord-306424-gf0bglm0	31	28	and	and	CC
cord-306424-gf0bglm0	31	29	emphasize	emphasize	VB
cord-306424-gf0bglm0	31	30	the	the	DT
cord-306424-gf0bglm0	31	31	need	need	NN
cord-306424-gf0bglm0	31	32	for	for	IN
cord-306424-gf0bglm0	31	33	a	a	DT
cord-306424-gf0bglm0	31	34	precise	precise	JJ
cord-306424-gf0bglm0	31	35	understanding	understanding	NN
cord-306424-gf0bglm0	31	36	of	of	IN
cord-306424-gf0bglm0	31	37	host	host	NN
cord-306424-gf0bglm0	31	38	-	-	HYPH
cord-306424-gf0bglm0	31	39	pathogen	pathogen	NN
cord-306424-gf0bglm0	31	40	interactions	interaction	NNS
cord-306424-gf0bglm0	31	41	to	to	TO
cord-306424-gf0bglm0	31	42	facilitate	facilitate	VB
cord-306424-gf0bglm0	31	43	development	development	NN
cord-306424-gf0bglm0	31	44	of	of	IN
cord-306424-gf0bglm0	31	45	novel	novel	JJ
cord-306424-gf0bglm0	31	46	antiviral	antiviral	JJ
cord-306424-gf0bglm0	31	47	therapies	therapy	NNS
cord-306424-gf0bglm0	31	48	or	or	CC
cord-306424-gf0bglm0	31	49	vaccination	vaccination	NN
cord-306424-gf0bglm0	31	50	methods	method	NNS
cord-306424-gf0bglm0	31	51	.	.	.
cord-306424-gf0bglm0	32	1	Over	over	IN
cord-306424-gf0bglm0	32	2	the	the	DT
cord-306424-gf0bglm0	32	3	last	last	JJ
cord-306424-gf0bglm0	32	4	decades	decade	NNS
cord-306424-gf0bglm0	32	5	,	,	,
cord-306424-gf0bglm0	32	6	many	many	JJ
cord-306424-gf0bglm0	32	7	+	+	CC
cord-306424-gf0bglm0	32	8	RNA	rna	NN
cord-306424-gf0bglm0	32	9	viruses	virus	NNS
cord-306424-gf0bglm0	32	10	have	have	VBP
cord-306424-gf0bglm0	32	11	been	be	VBN
cord-306424-gf0bglm0	32	12	extensively	extensively	RB
cord-306424-gf0bglm0	32	13	studied	study	VBN
cord-306424-gf0bglm0	32	14	for	for	IN
cord-306424-gf0bglm0	32	15	their	-PRON-	PRP$
cord-306424-gf0bglm0	32	16	intriguing	intriguing	JJ
cord-306424-gf0bglm0	32	17	biology	biology	NN
cord-306424-gf0bglm0	32	18	,	,	,
cord-306424-gf0bglm0	32	19	including	include	VBG
cord-306424-gf0bglm0	32	20	coronaviruses	coronaviruse	NNS
cord-306424-gf0bglm0	32	21	as	as	IN
cord-306424-gf0bglm0	32	22	those	those	DT
cord-306424-gf0bglm0	32	23	mentioned	mention	VBN
cord-306424-gf0bglm0	32	24	above	above	RB
cord-306424-gf0bglm0	32	25	,	,	,
cord-306424-gf0bglm0	32	26	picornaviruses	picornavirus	NNS
cord-306424-gf0bglm0	32	27	such	such	JJ
cord-306424-gf0bglm0	32	28	as	as	IN
cord-306424-gf0bglm0	32	29	coxsackievirus	coxsackievirus	NNP
cord-306424-gf0bglm0	32	30	and	and	CC
cord-306424-gf0bglm0	32	31	poliovirus	poliovirus	NN
cord-306424-gf0bglm0	32	32	,	,	,
cord-306424-gf0bglm0	32	33	and	and	CC
cord-306424-gf0bglm0	32	34	flaviviruses	flavivirus	NNS
cord-306424-gf0bglm0	32	35	such	such	JJ
cord-306424-gf0bglm0	32	36	as	as	IN
cord-306424-gf0bglm0	32	37	West	West	NNP
cord-306424-gf0bglm0	32	38	Nile	Nile	NNP
cord-306424-gf0bglm0	32	39	virus	virus	NN
cord-306424-gf0bglm0	32	40	(	(	-LRB-
cord-306424-gf0bglm0	32	41	WNV	WNV	NNP
cord-306424-gf0bglm0	32	42	)	)	-RRB-
cord-306424-gf0bglm0	32	43	,	,	,
cord-306424-gf0bglm0	32	44	Hepatitis	Hepatitis	NNP
cord-306424-gf0bglm0	32	45	C	C	NNP
cord-306424-gf0bglm0	32	46	virus	virus	NN
cord-306424-gf0bglm0	32	47	(	(	-LRB-
cord-306424-gf0bglm0	32	48	HCV	HCV	NNP
cord-306424-gf0bglm0	32	49	)	)	-RRB-
cord-306424-gf0bglm0	32	50	,	,	,
cord-306424-gf0bglm0	32	51	dengue	dengue	NN
cord-306424-gf0bglm0	32	52	virus	virus	NN
cord-306424-gf0bglm0	32	53	(	(	-LRB-
cord-306424-gf0bglm0	32	54	DENV	DENV	NNP
cord-306424-gf0bglm0	32	55	)	)	-RRB-
cord-306424-gf0bglm0	32	56	,	,	,
cord-306424-gf0bglm0	32	57	Zika	Zika	NNP
cord-306424-gf0bglm0	32	58	virus	virus	NN
cord-306424-gf0bglm0	32	59	,	,	,
cord-306424-gf0bglm0	32	60	and	and	CC
cord-306424-gf0bglm0	32	61	Japanese	japanese	JJ
cord-306424-gf0bglm0	32	62	encephalitis	encephalitis	NN
cord-306424-gf0bglm0	32	63	virus	virus	NN
cord-306424-gf0bglm0	32	64	(	(	-LRB-
cord-306424-gf0bglm0	32	65	JEV	JEV	NNP
cord-306424-gf0bglm0	32	66	)	)	-RRB-
cord-306424-gf0bglm0	32	67	,	,	,
cord-306424-gf0bglm0	32	68	as	as	RB
cord-306424-gf0bglm0	32	69	well	well	RB
cord-306424-gf0bglm0	32	70	as	as	IN
cord-306424-gf0bglm0	32	71	the	the	DT
cord-306424-gf0bglm0	32	72	family	family	NN
cord-306424-gf0bglm0	32	73	of	of	IN
cord-306424-gf0bglm0	32	74	togaviridae	togaviridae	NNP
cord-306424-gf0bglm0	32	75	,	,	,
cord-306424-gf0bglm0	32	76	including	include	VBG
cord-306424-gf0bglm0	32	77	rubella	rubella	NN
cord-306424-gf0bglm0	32	78	virus	virus	NN
cord-306424-gf0bglm0	32	79	and	and	CC
cord-306424-gf0bglm0	32	80	chikungunya	chikungunya	NN
cord-306424-gf0bglm0	32	81	virus	virus	NN
cord-306424-gf0bglm0	32	82	.	.	.
cord-306424-gf0bglm0	33	1	One	one	CD
cord-306424-gf0bglm0	33	2	of	of	IN
cord-306424-gf0bglm0	33	3	the	the	DT
cord-306424-gf0bglm0	33	4	intriguing	intriguing	JJ
cord-306424-gf0bglm0	33	5	features	feature	NNS
cord-306424-gf0bglm0	33	6	that	that	WDT
cord-306424-gf0bglm0	33	7	is	be	VBZ
cord-306424-gf0bglm0	33	8	shared	share	VBN
cord-306424-gf0bglm0	33	9	by	by	IN
cord-306424-gf0bglm0	33	10	all	all	DT
cord-306424-gf0bglm0	33	11	+	+	SYM
cord-306424-gf0bglm0	33	12	RNA	RNA	NNP
cord-306424-gf0bglm0	33	13	viruses	virus	NNS
cord-306424-gf0bglm0	33	14	is	be	VBZ
cord-306424-gf0bglm0	33	15	the	the	DT
cord-306424-gf0bglm0	33	16	rearrangement	rearrangement	NN
cord-306424-gf0bglm0	33	17	of	of	IN
cord-306424-gf0bglm0	33	18	host	host	NN
cord-306424-gf0bglm0	33	19	membranes	membrane	NNS
cord-306424-gf0bglm0	33	20	into	into	IN
cord-306424-gf0bglm0	33	21	viral	viral	JJ
cord-306424-gf0bglm0	33	22	ROs	ro	NNS
cord-306424-gf0bglm0	33	23	,	,	,
cord-306424-gf0bglm0	33	24	whereby	whereby	WRB
cord-306424-gf0bglm0	33	25	particular	particular	JJ
cord-306424-gf0bglm0	33	26	cellular	cellular	JJ
cord-306424-gf0bglm0	33	27	organelles	organelle	NNS
cord-306424-gf0bglm0	33	28	(	(	-LRB-
cord-306424-gf0bglm0	33	29	depending	depend	VBG
cord-306424-gf0bglm0	33	30	on	on	IN
cord-306424-gf0bglm0	33	31	the	the	DT
cord-306424-gf0bglm0	33	32	virus	virus	NN
cord-306424-gf0bglm0	33	33	)	)	-RRB-
cord-306424-gf0bglm0	33	34	are	be	VBP
cord-306424-gf0bglm0	33	35	used	use	VBN
cord-306424-gf0bglm0	33	36	as	as	IN
cord-306424-gf0bglm0	33	37	membrane	membrane	NN
cord-306424-gf0bglm0	33	38	donors	donor	NNS
cord-306424-gf0bglm0	33	39	.	.	.
cord-306424-gf0bglm0	34	1	Concerning	concern	VBG
cord-306424-gf0bglm0	34	2	their	-PRON-	PRP$
cord-306424-gf0bglm0	34	3	role	role	NN
cord-306424-gf0bglm0	34	4	in	in	IN
cord-306424-gf0bglm0	34	5	viral	viral	JJ
cord-306424-gf0bglm0	34	6	RNA	RNA	NNP
cord-306424-gf0bglm0	34	7	replication	replication	NN
cord-306424-gf0bglm0	34	8	,	,	,
cord-306424-gf0bglm0	34	9	it	-PRON-	PRP
cord-306424-gf0bglm0	34	10	is	be	VBZ
cord-306424-gf0bglm0	34	11	thought	think	VBN
cord-306424-gf0bglm0	34	12	that	that	IN
cord-306424-gf0bglm0	34	13	the	the	DT
cord-306424-gf0bglm0	34	14	structures	structure	NNS
cord-306424-gf0bglm0	34	15	form	form	VBP
cord-306424-gf0bglm0	34	16	a	a	DT
cord-306424-gf0bglm0	34	17	scaffold	scaffold	NN
cord-306424-gf0bglm0	34	18	that	that	WDT
cord-306424-gf0bglm0	34	19	improves	improve	VBZ
cord-306424-gf0bglm0	34	20	efficiency	efficiency	NN
cord-306424-gf0bglm0	34	21	of	of	IN
cord-306424-gf0bglm0	34	22	enzymatic	enzymatic	JJ
cord-306424-gf0bglm0	34	23	reactions	reaction	NNS
cord-306424-gf0bglm0	34	24	and	and	CC
cord-306424-gf0bglm0	34	25	provides	provide	VBZ
cord-306424-gf0bglm0	34	26	a	a	DT
cord-306424-gf0bglm0	34	27	spatiotemporal	spatiotemporal	JJ
cord-306424-gf0bglm0	34	28	regulation	regulation	NN
cord-306424-gf0bglm0	34	29	of	of	IN
cord-306424-gf0bglm0	34	30	the	the	DT
cord-306424-gf0bglm0	34	31	different	different	JJ
cord-306424-gf0bglm0	34	32	stages	stage	NNS
cord-306424-gf0bglm0	34	33	in	in	IN
cord-306424-gf0bglm0	34	34	the	the	DT
cord-306424-gf0bglm0	34	35	virus	virus	NN
cord-306424-gf0bglm0	34	36	life	life	NN
cord-306424-gf0bglm0	34	37	cycle	cycle	NN
cord-306424-gf0bglm0	34	38	.	.	.
cord-306424-gf0bglm0	35	1	Besides	besides	IN
cord-306424-gf0bglm0	35	2	this	this	DT
cord-306424-gf0bglm0	35	3	,	,	,
cord-306424-gf0bglm0	35	4	it	-PRON-	PRP
cord-306424-gf0bglm0	35	5	is	be	VBZ
cord-306424-gf0bglm0	35	6	thought	think	VBN
cord-306424-gf0bglm0	35	7	that	that	IN
cord-306424-gf0bglm0	35	8	ROs	ROs	NNP
cord-306424-gf0bglm0	35	9	have	have	VB
cord-306424-gf0bglm0	35	10	an	an	DT
cord-306424-gf0bglm0	35	11	important	important	JJ
cord-306424-gf0bglm0	35	12	role	role	NN
cord-306424-gf0bglm0	35	13	in	in	IN
cord-306424-gf0bglm0	35	14	shielding	shield	VBG
cord-306424-gf0bglm0	35	15	viral	viral	JJ
cord-306424-gf0bglm0	35	16	RNA	RNA	NNP
cord-306424-gf0bglm0	35	17	products	product	NNS
cord-306424-gf0bglm0	35	18	from	from	IN
cord-306424-gf0bglm0	35	19	the	the	DT
cord-306424-gf0bglm0	35	20	RNA	RNA	NNP
cord-306424-gf0bglm0	35	21	sensors	sensor	NNS
cord-306424-gf0bglm0	35	22	of	of	IN
cord-306424-gf0bglm0	35	23	the	the	DT
cord-306424-gf0bglm0	35	24	innate	innate	JJ
cord-306424-gf0bglm0	35	25	immune	immune	JJ
cord-306424-gf0bglm0	35	26	system	system	NN
cord-306424-gf0bglm0	35	27	.	.	.
cord-306424-gf0bglm0	36	1	ROs	ro	NNS
cord-306424-gf0bglm0	36	2	are	be	VBP
cord-306424-gf0bglm0	36	3	therefore	therefore	RB
cord-306424-gf0bglm0	36	4	believed	believe	VBN
cord-306424-gf0bglm0	36	5	to	to	TO
cord-306424-gf0bglm0	36	6	have	have	VB
cord-306424-gf0bglm0	36	7	a	a	DT
cord-306424-gf0bglm0	36	8	dual	dual	JJ
cord-306424-gf0bglm0	36	9	role	role	NN
cord-306424-gf0bglm0	36	10	in	in	IN
cord-306424-gf0bglm0	36	11	+	+	CC
cord-306424-gf0bglm0	36	12	RNA	RNA	NNP
cord-306424-gf0bglm0	36	13	virus	virus	NN
cord-306424-gf0bglm0	36	14	infection	infection	NN
cord-306424-gf0bglm0	36	15	and	and	CC
cord-306424-gf0bglm0	36	16	innate	innate	JJ
cord-306424-gf0bglm0	36	17	immune	immune	JJ
cord-306424-gf0bglm0	36	18	evasion	evasion	NN
cord-306424-gf0bglm0	36	19	,	,	,
cord-306424-gf0bglm0	36	20	which	which	WDT
cord-306424-gf0bglm0	36	21	will	will	MD
cord-306424-gf0bglm0	36	22	be	be	VB
cord-306424-gf0bglm0	36	23	elaborated	elaborate	VBN
cord-306424-gf0bglm0	36	24	on	on	IN
cord-306424-gf0bglm0	36	25	further	far	RBR
cord-306424-gf0bglm0	36	26	in	in	IN
cord-306424-gf0bglm0	36	27	this	this	DT
cord-306424-gf0bglm0	36	28	review	review	NN
cord-306424-gf0bglm0	36	29	.	.	.
cord-306424-gf0bglm0	37	1	Several	several	JJ
cord-306424-gf0bglm0	37	2	comprehensive	comprehensive	JJ
cord-306424-gf0bglm0	37	3	reviews	review	NNS
cord-306424-gf0bglm0	37	4	have	have	VBP
cord-306424-gf0bglm0	37	5	recently	recently	RB
cord-306424-gf0bglm0	37	6	described	describe	VBN
cord-306424-gf0bglm0	37	7	the	the	DT
cord-306424-gf0bglm0	37	8	current	current	JJ
cord-306424-gf0bglm0	37	9	knowledge	knowledge	NN
cord-306424-gf0bglm0	37	10	of	of	IN
cord-306424-gf0bglm0	37	11	these	these	DT
cord-306424-gf0bglm0	37	12	structures	structure	NNS
cord-306424-gf0bglm0	37	13	[	[	-LRB-
cord-306424-gf0bglm0	37	14	12	12	CD
cord-306424-gf0bglm0	37	15	,	,	,
cord-306424-gf0bglm0	37	16	[	[	-LRB-
cord-306424-gf0bglm0	37	17	18	18	CD
cord-306424-gf0bglm0	37	18	]	]	-RRB-
cord-306424-gf0bglm0	37	19	[	[	-LRB-
cord-306424-gf0bglm0	37	20	19	19	CD
cord-306424-gf0bglm0	37	21	]	]	-RRB-
cord-306424-gf0bglm0	37	22	[	[	-LRB-
cord-306424-gf0bglm0	37	23	20	20	CD
cord-306424-gf0bglm0	37	24	]	]	-RRB-
cord-306424-gf0bglm0	37	25	,	,	,
cord-306424-gf0bglm0	37	26	therefore	therefore	RB
cord-306424-gf0bglm0	37	27	we	-PRON-	PRP
cord-306424-gf0bglm0	37	28	will	will	MD
cord-306424-gf0bglm0	37	29	only	only	RB
cord-306424-gf0bglm0	37	30	briefly	briefly	RB
cord-306424-gf0bglm0	37	31	summarize	summarize	VB
cord-306424-gf0bglm0	37	32	this	this	DT
cord-306424-gf0bglm0	37	33	below	below	RB
cord-306424-gf0bglm0	37	34	.	.	.
cord-306424-gf0bglm0	38	1	Most	Most	JJS
cord-306424-gf0bglm0	38	2	studies	study	NNS
cord-306424-gf0bglm0	38	3	until	until	IN
cord-306424-gf0bglm0	38	4	now	now	RB
cord-306424-gf0bglm0	38	5	focused	focus	VBN
cord-306424-gf0bglm0	38	6	on	on	IN
cord-306424-gf0bglm0	38	7	the	the	DT
cord-306424-gf0bglm0	38	8	architecture	architecture	NN
cord-306424-gf0bglm0	38	9	of	of	IN
cord-306424-gf0bglm0	38	10	structures	structure	NNS
cord-306424-gf0bglm0	38	11	induced	induce	VBN
cord-306424-gf0bglm0	38	12	by	by	IN
cord-306424-gf0bglm0	38	13	different	different	JJ
cord-306424-gf0bglm0	38	14	viruses	virus	NNS
cord-306424-gf0bglm0	38	15	,	,	,
cord-306424-gf0bglm0	38	16	and	and	CC
cord-306424-gf0bglm0	38	17	based	base	VBN
cord-306424-gf0bglm0	38	18	on	on	IN
cord-306424-gf0bglm0	38	19	electron	electron	NN
cord-306424-gf0bglm0	38	20	microscopy	microscopy	NN
cord-306424-gf0bglm0	38	21	and	and	CC
cord-306424-gf0bglm0	38	22	electron	electron	NN
cord-306424-gf0bglm0	38	23	tomography	tomography	NN
cord-306424-gf0bglm0	38	24	,	,	,
cord-306424-gf0bglm0	38	25	ROs	ROs	NNP
cord-306424-gf0bglm0	38	26	were	be	VBD
cord-306424-gf0bglm0	38	27	categorized	categorize	VBN
cord-306424-gf0bglm0	38	28	into	into	IN
cord-306424-gf0bglm0	38	29	two	two	CD
cord-306424-gf0bglm0	38	30	different	different	JJ
cord-306424-gf0bglm0	38	31	classes	class	NNS
cord-306424-gf0bglm0	38	32	:	:	:
cord-306424-gf0bglm0	38	33	the	the	DT
cord-306424-gf0bglm0	38	34	invaginated	invaginated	JJ
cord-306424-gf0bglm0	38	35	vesicle	vesicle	NN
cord-306424-gf0bglm0	38	36	/	/	SYM
cord-306424-gf0bglm0	38	37	spherule	spherule	NNP
cord-306424-gf0bglm0	38	38	(	(	-LRB-
cord-306424-gf0bglm0	38	39	Inv	Inv	NNP
cord-306424-gf0bglm0	38	40	)	)	-RRB-
cord-306424-gf0bglm0	38	41	type	type	NN
cord-306424-gf0bglm0	38	42	,	,	,
cord-306424-gf0bglm0	38	43	and	and	CC
cord-306424-gf0bglm0	38	44	the	the	DT
cord-306424-gf0bglm0	38	45	double	double	JJ
cord-306424-gf0bglm0	38	46	membrane	membrane	NN
cord-306424-gf0bglm0	38	47	vesicle	vesicle	NN
cord-306424-gf0bglm0	38	48	(	(	-LRB-
cord-306424-gf0bglm0	38	49	DMV	DMV	NNP
cord-306424-gf0bglm0	38	50	)	)	-RRB-
cord-306424-gf0bglm0	38	51	type	type	NN
cord-306424-gf0bglm0	38	52	(	(	-LRB-
cord-306424-gf0bglm0	38	53	Fig	Fig	NNP
cord-306424-gf0bglm0	38	54	.	.	.
cord-306424-gf0bglm0	38	55	1	1	CD
cord-306424-gf0bglm0	38	56	)	)	-RRB-
cord-306424-gf0bglm0	38	57	.	.	.
cord-306424-gf0bglm0	39	1	Inv	Inv	NNP
cord-306424-gf0bglm0	39	2	ROs	ROs	NNP
cord-306424-gf0bglm0	39	3	are	be	VBP
cord-306424-gf0bglm0	39	4	predominantly	predominantly	RB
cord-306424-gf0bglm0	39	5	observed	observe	VBN
cord-306424-gf0bglm0	39	6	during	during	IN
cord-306424-gf0bglm0	39	7	infection	infection	NN
cord-306424-gf0bglm0	39	8	with	with	IN
cord-306424-gf0bglm0	39	9	alphaviruses	alphavirus	NNS
cord-306424-gf0bglm0	39	10	,	,	,
cord-306424-gf0bglm0	39	11	such	such	JJ
cord-306424-gf0bglm0	39	12	as	as	IN
cord-306424-gf0bglm0	39	13	Semliki	Semliki	NNP
cord-306424-gf0bglm0	39	14	Forest	Forest	NNP
cord-306424-gf0bglm0	39	15	virus	virus	NN
cord-306424-gf0bglm0	39	16	and	and	CC
cord-306424-gf0bglm0	39	17	Sindbis	Sindbis	NNP
cord-306424-gf0bglm0	39	18	virus	virus	NN
cord-306424-gf0bglm0	39	19	,	,	,
cord-306424-gf0bglm0	39	20	nodavirideae	nodavirideae	NNP
cord-306424-gf0bglm0	39	21	such	such	JJ
cord-306424-gf0bglm0	39	22	as	as	IN
cord-306424-gf0bglm0	39	23	Flock	Flock	NNP
cord-306424-gf0bglm0	39	24	House	House	NNP
cord-306424-gf0bglm0	39	25	virus	virus	NN
cord-306424-gf0bglm0	39	26	,	,	,
cord-306424-gf0bglm0	39	27	bromoviridae	bromoviridae	NNP
cord-306424-gf0bglm0	39	28	such	such	JJ
cord-306424-gf0bglm0	39	29	as	as	IN
cord-306424-gf0bglm0	39	30	bromovirus	bromovirus	NNP
cord-306424-gf0bglm0	39	31	,	,	,
cord-306424-gf0bglm0	39	32	and	and	CC
cord-306424-gf0bglm0	39	33	flaviviridae	flaviviridae	VBD
cord-306424-gf0bglm0	39	34	such	such	JJ
cord-306424-gf0bglm0	39	35	as	as	IN
cord-306424-gf0bglm0	39	36	rubella	rubella	NN
cord-306424-gf0bglm0	39	37	virus	virus	NN
cord-306424-gf0bglm0	39	38	,	,	,
cord-306424-gf0bglm0	39	39	DENV	DENV	NNP
cord-306424-gf0bglm0	39	40	,	,	,
cord-306424-gf0bglm0	39	41	and	and	CC
cord-306424-gf0bglm0	39	42	WNV	WNV	NNP
cord-306424-gf0bglm0	39	43	[	[	-LRB-
cord-306424-gf0bglm0	39	44	19	19	CD
cord-306424-gf0bglm0	39	45	,	,	,
cord-306424-gf0bglm0	39	46	21	21	CD
cord-306424-gf0bglm0	39	47	]	]	-RRB-
cord-306424-gf0bglm0	39	48	.	.	.
cord-306424-gf0bglm0	40	1	Although	although	IN
cord-306424-gf0bglm0	40	2	the	the	DT
cord-306424-gf0bglm0	40	3	location	location	NN
cord-306424-gf0bglm0	40	4	and	and	CC
cord-306424-gf0bglm0	40	5	dynamics	dynamic	NNS
cord-306424-gf0bglm0	40	6	of	of	IN
cord-306424-gf0bglm0	40	7	the	the	DT
cord-306424-gf0bglm0	40	8	formation	formation	NN
cord-306424-gf0bglm0	40	9	of	of	IN
cord-306424-gf0bglm0	40	10	Inv	Inv	NNP
cord-306424-gf0bglm0	40	11	ROs	ROs	NNP
cord-306424-gf0bglm0	40	12	varies	vary	VBZ
cord-306424-gf0bglm0	40	13	per	per	IN
cord-306424-gf0bglm0	40	14	virus	virus	NN
cord-306424-gf0bglm0	40	15	,	,	,
cord-306424-gf0bglm0	40	16	the	the	DT
cord-306424-gf0bglm0	40	17	result	result	NN
cord-306424-gf0bglm0	40	18	is	be	VBZ
cord-306424-gf0bglm0	40	19	a	a	DT
cord-306424-gf0bglm0	40	20	single	single	JJ
cord-306424-gf0bglm0	40	21	membrane	membrane	NN
cord-306424-gf0bglm0	40	22	invagination	invagination	NN
cord-306424-gf0bglm0	40	23	of	of	IN
cord-306424-gf0bglm0	40	24	which	which	WDT
cord-306424-gf0bglm0	40	25	the	the	DT
cord-306424-gf0bglm0	40	26	content	content	NN
cord-306424-gf0bglm0	40	27	is	be	VBZ
cord-306424-gf0bglm0	40	28	connected	connect	VBN
cord-306424-gf0bglm0	40	29	to	to	IN
cord-306424-gf0bglm0	40	30	the	the	DT
cord-306424-gf0bglm0	40	31	cytosol	cytosol	NN
cord-306424-gf0bglm0	40	32	.	.	.
cord-306424-gf0bglm0	41	1	In	in	IN
cord-306424-gf0bglm0	41	2	addition	addition	NN
cord-306424-gf0bglm0	41	3	,	,	,
cord-306424-gf0bglm0	41	4	replicase	replicase	NN
cord-306424-gf0bglm0	41	5	proteins	protein	NNS
cord-306424-gf0bglm0	41	6	and	and	CC
cord-306424-gf0bglm0	41	7	newly	newly	RB
cord-306424-gf0bglm0	41	8	synthesized	synthesize	VBN
cord-306424-gf0bglm0	41	9	viral	viral	JJ
cord-306424-gf0bglm0	41	10	RNA	RNA	NNP
cord-306424-gf0bglm0	41	11	were	be	VBD
cord-306424-gf0bglm0	41	12	observed	observe	VBN
cord-306424-gf0bglm0	41	13	in	in	IN
cord-306424-gf0bglm0	41	14	these	these	DT
cord-306424-gf0bglm0	41	15	spherules	spherule	NNS
cord-306424-gf0bglm0	41	16	,	,	,
cord-306424-gf0bglm0	41	17	strongly	strongly	RB
cord-306424-gf0bglm0	41	18	suggesting	suggest	VBG
cord-306424-gf0bglm0	41	19	that	that	IN
cord-306424-gf0bglm0	41	20	Inv	Inv	NNP
cord-306424-gf0bglm0	41	21	ROs	ROs	NNP
cord-306424-gf0bglm0	41	22	are	be	VBP
cord-306424-gf0bglm0	41	23	sites	site	NNS
cord-306424-gf0bglm0	41	24	of	of	IN
cord-306424-gf0bglm0	41	25	viral	viral	JJ
cord-306424-gf0bglm0	41	26	RNA	RNA	NNP
cord-306424-gf0bglm0	41	27	replication	replication	NN
cord-306424-gf0bglm0	41	28	[	[	-LRB-
cord-306424-gf0bglm0	41	29	22	22	CD
cord-306424-gf0bglm0	41	30	]	]	-RRB-
cord-306424-gf0bglm0	42	1	[	[	-LRB-
cord-306424-gf0bglm0	42	2	23	23	CD
cord-306424-gf0bglm0	42	3	]	]	-RRB-
cord-306424-gf0bglm0	42	4	[	[	-LRB-
cord-306424-gf0bglm0	42	5	24	24	CD
cord-306424-gf0bglm0	42	6	]	]	-RRB-
cord-306424-gf0bglm0	42	7	.	.	.
cord-306424-gf0bglm0	43	1	Furthermore	furthermore	RB
cord-306424-gf0bglm0	43	2	,	,	,
cord-306424-gf0bglm0	43	3	ribosomes	ribosome	NNS
cord-306424-gf0bglm0	43	4	are	be	VBP
cord-306424-gf0bglm0	43	5	found	find	VBN
cord-306424-gf0bglm0	43	6	in	in	IN
cord-306424-gf0bglm0	43	7	close	close	JJ
cord-306424-gf0bglm0	43	8	proximity	proximity	NN
cord-306424-gf0bglm0	43	9	of	of	IN
cord-306424-gf0bglm0	43	10	some	some	DT
cord-306424-gf0bglm0	43	11	Inv	Inv	NNP
cord-306424-gf0bglm0	43	12	ROs	ROs	NNP
cord-306424-gf0bglm0	43	13	[	[	-LRB-
cord-306424-gf0bglm0	43	14	25	25	CD
cord-306424-gf0bglm0	43	15	]	]	-RRB-
cord-306424-gf0bglm0	43	16	,	,	,
cord-306424-gf0bglm0	43	17	suggesting	suggest	VBG
cord-306424-gf0bglm0	43	18	that	that	IN
cord-306424-gf0bglm0	43	19	viral	viral	JJ
cord-306424-gf0bglm0	43	20	RNA	RNA	NNP
cord-306424-gf0bglm0	43	21	replication	replication	NN
cord-306424-gf0bglm0	43	22	and	and	CC
cord-306424-gf0bglm0	43	23	translation	translation	NN
cord-306424-gf0bglm0	43	24	are	be	VBP
cord-306424-gf0bglm0	43	25	spatially	spatially	RB
cord-306424-gf0bglm0	43	26	separated	separate	VBN
cord-306424-gf0bglm0	43	27	.	.	.
cord-306424-gf0bglm0	44	1	A	a	DT
cord-306424-gf0bglm0	44	2	similar	similar	JJ
cord-306424-gf0bglm0	44	3	organization	organization	NN
cord-306424-gf0bglm0	44	4	of	of	IN
cord-306424-gf0bglm0	44	5	Inv	Inv	NNP
cord-306424-gf0bglm0	44	6	ROs	ROs	NNP
cord-306424-gf0bglm0	44	7	was	be	VBD
cord-306424-gf0bglm0	44	8	found	find	VBN
cord-306424-gf0bglm0	44	9	for	for	IN
cord-306424-gf0bglm0	44	10	Flock	Flock	NNP
cord-306424-gf0bglm0	44	11	House	House	NNP
cord-306424-gf0bglm0	44	12	virus	virus	NN
cord-306424-gf0bglm0	44	13	,	,	,
cord-306424-gf0bglm0	44	14	rubella	rubella	NN
cord-306424-gf0bglm0	44	15	virus	virus	NN
cord-306424-gf0bglm0	44	16	,	,	,
cord-306424-gf0bglm0	44	17	DENV	DENV	NNP
cord-306424-gf0bglm0	44	18	,	,	,
cord-306424-gf0bglm0	44	19	and	and	CC
cord-306424-gf0bglm0	44	20	WNV	WNV	NNP
cord-306424-gf0bglm0	44	21	.	.	.
cord-306424-gf0bglm0	45	1	Moreover	moreover	RB
cord-306424-gf0bglm0	45	2	,	,	,
cord-306424-gf0bglm0	45	3	a	a	DT
cord-306424-gf0bglm0	45	4	recent	recent	JJ
cord-306424-gf0bglm0	45	5	study	study	NN
cord-306424-gf0bglm0	45	6	visualized	visualize	VBD
cord-306424-gf0bglm0	45	7	virus	virus	NN
cord-306424-gf0bglm0	45	8	budding	bud	VBG
cord-306424-gf0bglm0	45	9	in	in	IN
cord-306424-gf0bglm0	45	10	close	close	JJ
cord-306424-gf0bglm0	45	11	association	association	NN
cord-306424-gf0bglm0	45	12	with	with	IN
cord-306424-gf0bglm0	45	13	Inv	Inv	NNP
cord-306424-gf0bglm0	45	14	ROs	ROs	NNP
cord-306424-gf0bglm0	45	15	,	,	,
cord-306424-gf0bglm0	45	16	suggesting	suggest	VBG
cord-306424-gf0bglm0	45	17	a	a	DT
cord-306424-gf0bglm0	45	18	direct	direct	JJ
cord-306424-gf0bglm0	45	19	role	role	NN
cord-306424-gf0bglm0	45	20	for	for	IN
cord-306424-gf0bglm0	45	21	these	these	DT
cord-306424-gf0bglm0	45	22	structures	structure	NNS
cord-306424-gf0bglm0	45	23	in	in	IN
cord-306424-gf0bglm0	45	24	coordinating	coordinate	VBG
cord-306424-gf0bglm0	45	25	virus	virus	NN
cord-306424-gf0bglm0	45	26	assembly	assembly	NN
cord-306424-gf0bglm0	45	27	[	[	-LRB-
cord-306424-gf0bglm0	45	28	26	26	CD
cord-306424-gf0bglm0	45	29	]	]	-RRB-
cord-306424-gf0bglm0	45	30	.	.	.
cord-306424-gf0bglm0	46	1	Alternatively	alternatively	RB
cord-306424-gf0bglm0	46	2	,	,	,
cord-306424-gf0bglm0	46	3	DMV	DMV	NNP
cord-306424-gf0bglm0	46	4	ROs	ROs	NNP
cord-306424-gf0bglm0	46	5	are	be	VBP
cord-306424-gf0bglm0	46	6	known	know	VBN
cord-306424-gf0bglm0	46	7	to	to	TO
cord-306424-gf0bglm0	46	8	be	be	VB
cord-306424-gf0bglm0	46	9	formed	form	VBN
cord-306424-gf0bglm0	46	10	by	by	IN
cord-306424-gf0bglm0	46	11	enteroviruses	enteroviruses	NNP
cord-306424-gf0bglm0	46	12	such	such	JJ
cord-306424-gf0bglm0	46	13	as	as	IN
cord-306424-gf0bglm0	46	14	coxsackievirus	coxsackievirus	NNP
cord-306424-gf0bglm0	46	15	B3	b3	NN
cord-306424-gf0bglm0	46	16	and	and	CC
cord-306424-gf0bglm0	46	17	poliovirus	poliovirus	NN
cord-306424-gf0bglm0	46	18	,	,	,
cord-306424-gf0bglm0	46	19	coronaviruses	coronaviruse	NNS
cord-306424-gf0bglm0	46	20	such	such	JJ
cord-306424-gf0bglm0	46	21	as	as	IN
cord-306424-gf0bglm0	46	22	SARS	SARS	NNP
cord-306424-gf0bglm0	46	23	-	-	HYPH
cord-306424-gf0bglm0	46	24	CoV	CoV	NNP
cord-306424-gf0bglm0	46	25	and	and	CC
cord-306424-gf0bglm0	46	26	MERS	MERS	NNP
cord-306424-gf0bglm0	46	27	-	-	HYPH
cord-306424-gf0bglm0	46	28	CoV	CoV	NNP
cord-306424-gf0bglm0	46	29	,	,	,
cord-306424-gf0bglm0	46	30	arteriviruses	arteriviruse	NNS
cord-306424-gf0bglm0	46	31	such	such	JJ
cord-306424-gf0bglm0	46	32	as	as	IN
cord-306424-gf0bglm0	46	33	equine	equine	JJ
cord-306424-gf0bglm0	46	34	arteritis	arteritis	NN
cord-306424-gf0bglm0	46	35	virus	virus	NN
cord-306424-gf0bglm0	46	36	(	(	-LRB-
cord-306424-gf0bglm0	46	37	EAV	EAV	NNP
cord-306424-gf0bglm0	46	38	)	)	-RRB-
cord-306424-gf0bglm0	46	39	,	,	,
cord-306424-gf0bglm0	46	40	and	and	CC
cord-306424-gf0bglm0	46	41	the	the	DT
cord-306424-gf0bglm0	46	42	flavivirus	flavivirus	JJ
cord-306424-gf0bglm0	46	43	HCV	HCV	NNP
cord-306424-gf0bglm0	46	44	[	[	-LRB-
cord-306424-gf0bglm0	46	45	19	19	CD
cord-306424-gf0bglm0	46	46	,	,	,
cord-306424-gf0bglm0	46	47	27	27	CD
cord-306424-gf0bglm0	46	48	]	]	-RRB-
cord-306424-gf0bglm0	46	49	.	.	.
cord-306424-gf0bglm0	47	1	Besides	besides	IN
cord-306424-gf0bglm0	47	2	DMVs	dmv	NNS
cord-306424-gf0bglm0	47	3	,	,	,
cord-306424-gf0bglm0	47	4	for	for	IN
cord-306424-gf0bglm0	47	5	most	most	JJS
cord-306424-gf0bglm0	47	6	of	of	IN
cord-306424-gf0bglm0	47	7	these	these	DT
cord-306424-gf0bglm0	47	8	viruses	virus	NNS
cord-306424-gf0bglm0	47	9	other	other	JJ
cord-306424-gf0bglm0	47	10	kinds	kind	NNS
cord-306424-gf0bglm0	47	11	of	of	IN
cord-306424-gf0bglm0	47	12	structures	structure	NNS
cord-306424-gf0bglm0	47	13	are	be	VBP
cord-306424-gf0bglm0	47	14	found	find	VBN
cord-306424-gf0bglm0	47	15	during	during	IN
cord-306424-gf0bglm0	47	16	infection	infection	NN
cord-306424-gf0bglm0	47	17	,	,	,
cord-306424-gf0bglm0	47	18	mostly	mostly	RB
cord-306424-gf0bglm0	47	19	in	in	IN
cord-306424-gf0bglm0	47	20	close	close	JJ
cord-306424-gf0bglm0	47	21	proximity	proximity	NN
cord-306424-gf0bglm0	47	22	to	to	IN
cord-306424-gf0bglm0	47	23	the	the	DT
cord-306424-gf0bglm0	47	24	DMVs	dmv	NNS
cord-306424-gf0bglm0	47	25	themselves	-PRON-	PRP
cord-306424-gf0bglm0	47	26	,	,	,
cord-306424-gf0bglm0	47	27	such	such	JJ
cord-306424-gf0bglm0	47	28	as	as	IN
cord-306424-gf0bglm0	47	29	single	single	JJ
cord-306424-gf0bglm0	47	30	membrane	membrane	NN
cord-306424-gf0bglm0	47	31	vesicles	vesicle	NNS
cord-306424-gf0bglm0	47	32	,	,	,
cord-306424-gf0bglm0	47	33	multi	multi	JJ
cord-306424-gf0bglm0	47	34	-	-	JJ
cord-306424-gf0bglm0	47	35	membrane	membrane	JJ
cord-306424-gf0bglm0	47	36	vesicles	vesicle	NNS
cord-306424-gf0bglm0	47	37	,	,	,
cord-306424-gf0bglm0	47	38	vesicle	vesicle	NN
cord-306424-gf0bglm0	47	39	packets	packet	NNS
cord-306424-gf0bglm0	47	40	,	,	,
cord-306424-gf0bglm0	47	41	tubular	tubular	JJ
cord-306424-gf0bglm0	47	42	structures	structure	NNS
cord-306424-gf0bglm0	47	43	or	or	CC
cord-306424-gf0bglm0	47	44	zippered	zippered	JJ
cord-306424-gf0bglm0	47	45	ER	er	NN
cord-306424-gf0bglm0	47	46	membrane	membrane	NN
cord-306424-gf0bglm0	47	47	.	.	.
cord-306424-gf0bglm0	48	1	As	as	IN
cord-306424-gf0bglm0	48	2	for	for	IN
cord-306424-gf0bglm0	48	3	Inv	Inv	NNP
cord-306424-gf0bglm0	48	4	ROs	ROs	NNP
cord-306424-gf0bglm0	48	5	,	,	,
cord-306424-gf0bglm0	48	6	replicases	replicase	NNS
cord-306424-gf0bglm0	48	7	and	and	CC
cord-306424-gf0bglm0	48	8	viral	viral	JJ
cord-306424-gf0bglm0	48	9	RNA	RNA	NNP
cord-306424-gf0bglm0	48	10	of	of	IN
cord-306424-gf0bglm0	48	11	poliovirus	poliovirus	NN
cord-306424-gf0bglm0	48	12	,	,	,
cord-306424-gf0bglm0	48	13	EAV	EAV	NNP
cord-306424-gf0bglm0	48	14	,	,	,
cord-306424-gf0bglm0	48	15	and	and	CC
cord-306424-gf0bglm0	48	16	coxsackievirus	coxsackievirus	NNP
cord-306424-gf0bglm0	48	17	B3	B3	NNP
cord-306424-gf0bglm0	48	18	were	be	VBD
cord-306424-gf0bglm0	48	19	demonstrated	demonstrate	VBN
cord-306424-gf0bglm0	48	20	to	to	TO
cord-306424-gf0bglm0	48	21	localize	localize	VB
cord-306424-gf0bglm0	48	22	to	to	IN
cord-306424-gf0bglm0	48	23	DMVs	dmv	NNS
cord-306424-gf0bglm0	48	24	,	,	,
cord-306424-gf0bglm0	48	25	suggesting	suggest	VBG
cord-306424-gf0bglm0	48	26	that	that	IN
cord-306424-gf0bglm0	48	27	these	these	DT
cord-306424-gf0bglm0	48	28	structures	structure	NNS
cord-306424-gf0bglm0	48	29	might	may	MD
cord-306424-gf0bglm0	48	30	also	also	RB
cord-306424-gf0bglm0	48	31	support	support	VB
cord-306424-gf0bglm0	48	32	viral	viral	JJ
cord-306424-gf0bglm0	48	33	RNA	RNA	NNP
cord-306424-gf0bglm0	48	34	replication	replication	NN
cord-306424-gf0bglm0	48	35	.	.	.
cord-306424-gf0bglm0	49	1	Likewise	likewise	RB
cord-306424-gf0bglm0	49	2	,	,	,
cord-306424-gf0bglm0	49	3	for	for	IN
cord-306424-gf0bglm0	49	4	HCV	HCV	NNP
cord-306424-gf0bglm0	49	5	replicase	replicase	NN
cord-306424-gf0bglm0	49	6	proteins	protein	NNS
cord-306424-gf0bglm0	49	7	and	and	CC
cord-306424-gf0bglm0	49	8	viral	viral	JJ
cord-306424-gf0bglm0	49	9	RNA	RNA	NNP
cord-306424-gf0bglm0	49	10	were	be	VBD
cord-306424-gf0bglm0	49	11	predominantly	predominantly	RB
cord-306424-gf0bglm0	49	12	found	find	VBN
cord-306424-gf0bglm0	49	13	in	in	IN
cord-306424-gf0bglm0	49	14	DMVs	dmv	NNS
cord-306424-gf0bglm0	49	15	,	,	,
cord-306424-gf0bglm0	49	16	and	and	CC
cord-306424-gf0bglm0	49	17	the	the	DT
cord-306424-gf0bglm0	49	18	number	number	NN
cord-306424-gf0bglm0	49	19	of	of	IN
cord-306424-gf0bglm0	49	20	DMVs	dmv	NNS
cord-306424-gf0bglm0	49	21	positively	positively	RB
cord-306424-gf0bglm0	49	22	correlated	correlate	VBN
cord-306424-gf0bglm0	49	23	to	to	IN
cord-306424-gf0bglm0	49	24	the	the	DT
cord-306424-gf0bglm0	49	25	amount	amount	NN
cord-306424-gf0bglm0	49	26	of	of	IN
cord-306424-gf0bglm0	49	27	viral	viral	JJ
cord-306424-gf0bglm0	49	28	RNA	RNA	NNP
cord-306424-gf0bglm0	49	29	produced	produce	VBN
cord-306424-gf0bglm0	49	30	,	,	,
cord-306424-gf0bglm0	49	31	suggesting	suggest	VBG
cord-306424-gf0bglm0	49	32	that	that	IN
cord-306424-gf0bglm0	49	33	DMVs	dmv	NNS
cord-306424-gf0bglm0	49	34	indeed	indeed	RB
cord-306424-gf0bglm0	49	35	serve	serve	VBP
cord-306424-gf0bglm0	49	36	as	as	IN
cord-306424-gf0bglm0	49	37	sites	site	NNS
cord-306424-gf0bglm0	49	38	of	of	IN
cord-306424-gf0bglm0	49	39	RNA	RNA	NNP
cord-306424-gf0bglm0	49	40	replication	replication	NN
cord-306424-gf0bglm0	49	41	.	.	.
cord-306424-gf0bglm0	50	1	However	however	RB
cord-306424-gf0bglm0	50	2	,	,	,
cord-306424-gf0bglm0	50	3	for	for	IN
cord-306424-gf0bglm0	50	4	coronaviruses	coronaviruse	NNS
cord-306424-gf0bglm0	50	5	,	,	,
cord-306424-gf0bglm0	50	6	the	the	DT
cord-306424-gf0bglm0	50	7	number	number	NN
cord-306424-gf0bglm0	50	8	of	of	IN
cord-306424-gf0bglm0	50	9	DMVs	dmv	NNS
cord-306424-gf0bglm0	50	10	is	be	VBZ
cord-306424-gf0bglm0	50	11	not	not	RB
cord-306424-gf0bglm0	50	12	necessarily	necessarily	RB
cord-306424-gf0bglm0	50	13	proportional	proportional	JJ
cord-306424-gf0bglm0	50	14	to	to	TO
cord-306424-gf0bglm0	50	15	replication	replication	NN
cord-306424-gf0bglm0	50	16	capacity	capacity	NN
cord-306424-gf0bglm0	50	17	[	[	-LRB-
cord-306424-gf0bglm0	50	18	28	28	CD
cord-306424-gf0bglm0	50	19	,	,	,
cord-306424-gf0bglm0	50	20	29	29	CD
cord-306424-gf0bglm0	50	21	]	]	-RRB-
cord-306424-gf0bglm0	50	22	.	.	.
cord-306424-gf0bglm0	51	1	Also	also	RB
cord-306424-gf0bglm0	51	2	,	,	,
cord-306424-gf0bglm0	51	3	whereas	whereas	IN
cord-306424-gf0bglm0	51	4	SARS	SARS	NNP
cord-306424-gf0bglm0	51	5	-	-	HYPH
cord-306424-gf0bglm0	51	6	CoV	CoV	NNP
cord-306424-gf0bglm0	51	7	dsRNA	dsRNA	NNP
cord-306424-gf0bglm0	51	8	(	(	-LRB-
cord-306424-gf0bglm0	51	9	a	a	DT
cord-306424-gf0bglm0	51	10	replication	replication	NN
cord-306424-gf0bglm0	51	11	intermediate	intermediate	NN
cord-306424-gf0bglm0	51	12	)	)	-RRB-
cord-306424-gf0bglm0	51	13	was	be	VBD
cord-306424-gf0bglm0	51	14	found	find	VBN
cord-306424-gf0bglm0	51	15	inside	inside	IN
cord-306424-gf0bglm0	51	16	DMVs	dmv	NNS
cord-306424-gf0bglm0	51	17	,	,	,
cord-306424-gf0bglm0	51	18	replicase	replicase	NN
cord-306424-gf0bglm0	51	19	proteins	protein	NNS
cord-306424-gf0bglm0	51	20	were	be	VBD
cord-306424-gf0bglm0	51	21	more	more	RBR
cord-306424-gf0bglm0	51	22	abundant	abundant	JJ
cord-306424-gf0bglm0	51	23	in	in	IN
cord-306424-gf0bglm0	51	24	surrounding	surround	VBG
cord-306424-gf0bglm0	51	25	convoluted	convoluted	JJ
cord-306424-gf0bglm0	51	26	membranes	membrane	NNS
cord-306424-gf0bglm0	51	27	,	,	,
cord-306424-gf0bglm0	51	28	raising	raise	VBG
cord-306424-gf0bglm0	51	29	questions	question	NNS
cord-306424-gf0bglm0	51	30	regarding	regard	VBG
cord-306424-gf0bglm0	51	31	the	the	DT
cord-306424-gf0bglm0	51	32	spatial	spatial	JJ
cord-306424-gf0bglm0	51	33	organization	organization	NN
cord-306424-gf0bglm0	51	34	of	of	IN
cord-306424-gf0bglm0	51	35	SARS	SARS	NNP
cord-306424-gf0bglm0	51	36	-	-	HYPH
cord-306424-gf0bglm0	51	37	CoV	CoV	NNP
cord-306424-gf0bglm0	51	38	RNA	RNA	NNP
cord-306424-gf0bglm0	51	39	replication	replication	NN
cord-306424-gf0bglm0	51	40	.	.	.
cord-306424-gf0bglm0	52	1	The	the	DT
cord-306424-gf0bglm0	52	2	lack	lack	NN
cord-306424-gf0bglm0	52	3	of	of	IN
cord-306424-gf0bglm0	52	4	clear	clear	JJ
cord-306424-gf0bglm0	52	5	connections	connection	NNS
cord-306424-gf0bglm0	52	6	between	between	IN
cord-306424-gf0bglm0	52	7	the	the	DT
cord-306424-gf0bglm0	52	8	inside	inside	NN
cord-306424-gf0bglm0	52	9	of	of	IN
cord-306424-gf0bglm0	52	10	corona	corona	NN
cord-306424-gf0bglm0	52	11	-	-	HYPH
cord-306424-gf0bglm0	52	12	and	and	CC
cord-306424-gf0bglm0	52	13	arterivirus	arterivirus	NN
cord-306424-gf0bglm0	52	14	-	-	HYPH
cord-306424-gf0bglm0	52	15	induced	induce	VBN
cord-306424-gf0bglm0	52	16	DMVs	dmv	NNS
cord-306424-gf0bglm0	52	17	and	and	CC
cord-306424-gf0bglm0	52	18	the	the	DT
cord-306424-gf0bglm0	52	19	cytosol	cytosol	NN
cord-306424-gf0bglm0	52	20	(	(	-LRB-
cord-306424-gf0bglm0	52	21	where	where	WRB
cord-306424-gf0bglm0	52	22	the	the	DT
cord-306424-gf0bglm0	52	23	RNA	RNA	NNP
cord-306424-gf0bglm0	52	24	products	product	NNS
cord-306424-gf0bglm0	52	25	have	have	VBP
cord-306424-gf0bglm0	52	26	to	to	TO
cord-306424-gf0bglm0	52	27	go	go	VB
cord-306424-gf0bglm0	52	28	for	for	IN
cord-306424-gf0bglm0	52	29	translation	translation	NN
cord-306424-gf0bglm0	52	30	and	and	CC
cord-306424-gf0bglm0	52	31	particle	particle	NN
cord-306424-gf0bglm0	52	32	formation	formation	NN
cord-306424-gf0bglm0	52	33	)	)	-RRB-
cord-306424-gf0bglm0	52	34	further	further	RB
cord-306424-gf0bglm0	52	35	complicates	complicate	VBZ
cord-306424-gf0bglm0	52	36	our	-PRON-	PRP$
cord-306424-gf0bglm0	52	37	current	current	JJ
cord-306424-gf0bglm0	52	38	understanding	understanding	NN
cord-306424-gf0bglm0	52	39	of	of	IN
cord-306424-gf0bglm0	52	40	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	52	41	DMV	DMV	NNP
cord-306424-gf0bglm0	52	42	functionality	functionality	NN
cord-306424-gf0bglm0	52	43	[	[	-LRB-
cord-306424-gf0bglm0	52	44	30	30	CD
cord-306424-gf0bglm0	52	45	,	,	,
cord-306424-gf0bglm0	52	46	31	31	CD
cord-306424-gf0bglm0	52	47	]	]	-RRB-
cord-306424-gf0bglm0	52	48	.	.	.
cord-306424-gf0bglm0	53	1	Together	together	RB
cord-306424-gf0bglm0	53	2	,	,	,
cord-306424-gf0bglm0	53	3	these	these	DT
cord-306424-gf0bglm0	53	4	data	datum	NNS
cord-306424-gf0bglm0	53	5	continue	continue	VBP
cord-306424-gf0bglm0	53	6	to	to	TO
cord-306424-gf0bglm0	53	7	cause	cause	VB
cord-306424-gf0bglm0	53	8	debate	debate	NN
cord-306424-gf0bglm0	53	9	on	on	IN
cord-306424-gf0bglm0	53	10	the	the	DT
cord-306424-gf0bglm0	53	11	exact	exact	JJ
cord-306424-gf0bglm0	53	12	function	function	NN
cord-306424-gf0bglm0	53	13	of	of	IN
cord-306424-gf0bglm0	53	14	DMVs	dmv	NNS
cord-306424-gf0bglm0	53	15	and	and	CC
cord-306424-gf0bglm0	53	16	other	other	JJ
cord-306424-gf0bglm0	53	17	features	feature	NNS
cord-306424-gf0bglm0	53	18	of	of	IN
cord-306424-gf0bglm0	53	19	DMV	DMV	NNP
cord-306424-gf0bglm0	53	20	ROs	ROs	NNP
cord-306424-gf0bglm0	53	21	.	.	.
cord-306424-gf0bglm0	54	1	The	the	DT
cord-306424-gf0bglm0	54	2	notion	notion	NN
cord-306424-gf0bglm0	54	3	that	that	IN
cord-306424-gf0bglm0	54	4	expression	expression	NN
cord-306424-gf0bglm0	54	5	of	of	IN
cord-306424-gf0bglm0	54	6	combinations	combination	NNS
cord-306424-gf0bglm0	54	7	of	of	IN
cord-306424-gf0bglm0	54	8	non	non	JJ
cord-306424-gf0bglm0	54	9	-	-	JJ
cord-306424-gf0bglm0	54	10	structural	structural	JJ
cord-306424-gf0bglm0	54	11	viral	viral	JJ
cord-306424-gf0bglm0	54	12	proteins	protein	NNS
cord-306424-gf0bglm0	54	13	(	(	-LRB-
cord-306424-gf0bglm0	54	14	nsps	nsps	NNP
cord-306424-gf0bglm0	54	15	)	)	-RRB-
cord-306424-gf0bglm0	54	16	for	for	IN
cord-306424-gf0bglm0	54	17	some	some	DT
cord-306424-gf0bglm0	54	18	of	of	IN
cord-306424-gf0bglm0	54	19	these	these	DT
cord-306424-gf0bglm0	54	20	viruses	virus	NNS
cord-306424-gf0bglm0	54	21	mimics	mimic	VBZ
cord-306424-gf0bglm0	54	22	the	the	DT
cord-306424-gf0bglm0	54	23	formation	formation	NN
cord-306424-gf0bglm0	54	24	of	of	IN
cord-306424-gf0bglm0	54	25	membrane	membrane	NN
cord-306424-gf0bglm0	54	26	alterations	alteration	NNS
cord-306424-gf0bglm0	54	27	as	as	IN
cord-306424-gf0bglm0	54	28	observed	observe	VBN
cord-306424-gf0bglm0	54	29	during	during	IN
cord-306424-gf0bglm0	54	30	infection	infection	NN
cord-306424-gf0bglm0	54	31	confirms	confirm	VBZ
cord-306424-gf0bglm0	54	32	the	the	DT
cord-306424-gf0bglm0	54	33	viral	viral	JJ
cord-306424-gf0bglm0	54	34	induction	induction	NN
cord-306424-gf0bglm0	54	35	of	of	IN
cord-306424-gf0bglm0	54	36	these	these	DT
cord-306424-gf0bglm0	54	37	structures	structure	NNS
cord-306424-gf0bglm0	54	38	and	and	CC
cord-306424-gf0bglm0	54	39	opens	open	VBZ
cord-306424-gf0bglm0	54	40	possibilities	possibility	NNS
cord-306424-gf0bglm0	54	41	for	for	IN
cord-306424-gf0bglm0	54	42	detailed	detailed	JJ
cord-306424-gf0bglm0	54	43	study	study	NN
cord-306424-gf0bglm0	54	44	of	of	IN
cord-306424-gf0bglm0	54	45	this	this	DT
cord-306424-gf0bglm0	54	46	particular	particular	JJ
cord-306424-gf0bglm0	54	47	feature	feature	NN
cord-306424-gf0bglm0	54	48	of	of	IN
cord-306424-gf0bglm0	54	49	the	the	DT
cord-306424-gf0bglm0	54	50	infection	infection	NN
cord-306424-gf0bglm0	54	51	[	[	-LRB-
cord-306424-gf0bglm0	54	52	32	32	CD
cord-306424-gf0bglm0	54	53	]	]	-RRB-
cord-306424-gf0bglm0	54	54	[	[	-LRB-
cord-306424-gf0bglm0	54	55	33	33	CD
cord-306424-gf0bglm0	54	56	]	]	-RRB-
cord-306424-gf0bglm0	54	57	[	[	-LRB-
cord-306424-gf0bglm0	54	58	34	34	CD
cord-306424-gf0bglm0	54	59	]	]	-RRB-
cord-306424-gf0bglm0	54	60	.	.	.
cord-306424-gf0bglm0	55	1	3	3	LS
cord-306424-gf0bglm0	55	2	.	.	.
cord-306424-gf0bglm0	56	1	Innate	innate	JJ
cord-306424-gf0bglm0	56	2	immune	immune	JJ
cord-306424-gf0bglm0	56	3	recognition	recognition	NN
cord-306424-gf0bglm0	56	4	and	and	CC
cord-306424-gf0bglm0	56	5	responses	response	NNS
cord-306424-gf0bglm0	56	6	targeted	target	VBN
cord-306424-gf0bglm0	56	7	towards	towards	IN
cord-306424-gf0bglm0	56	8	viral	viral	JJ
cord-306424-gf0bglm0	56	9	RNA	RNA	NNP
cord-306424-gf0bglm0	56	10	replication	replication	NN
cord-306424-gf0bglm0	56	11	,	,	,
cord-306424-gf0bglm0	56	12	transcription	transcription	NN
cord-306424-gf0bglm0	56	13	,	,	,
cord-306424-gf0bglm0	56	14	and	and	CC
cord-306424-gf0bglm0	56	15	translation	translation	NN
cord-306424-gf0bglm0	56	16	Rapid	rapid	JJ
cord-306424-gf0bglm0	56	17	production	production	NN
cord-306424-gf0bglm0	56	18	of	of	IN
cord-306424-gf0bglm0	56	19	interferons	interferon	NNS
cord-306424-gf0bglm0	56	20	(	(	-LRB-
cord-306424-gf0bglm0	56	21	IFNs	ifns	NN
cord-306424-gf0bglm0	56	22	)	)	-RRB-
cord-306424-gf0bglm0	56	23	and	and	CC
cord-306424-gf0bglm0	56	24	pro	pro	JJ
cord-306424-gf0bglm0	56	25	-	-	JJ
cord-306424-gf0bglm0	56	26	inflammatory	inflammatory	JJ
cord-306424-gf0bglm0	56	27	cytokines	cytokine	NNS
cord-306424-gf0bglm0	56	28	is	be	VBZ
cord-306424-gf0bglm0	56	29	an	an	DT
cord-306424-gf0bglm0	56	30	important	important	JJ
cord-306424-gf0bglm0	56	31	consequence	consequence	NN
cord-306424-gf0bglm0	56	32	of	of	IN
cord-306424-gf0bglm0	56	33	virus	virus	NN
cord-306424-gf0bglm0	56	34	detection	detection	NN
cord-306424-gf0bglm0	56	35	,	,	,
cord-306424-gf0bglm0	56	36	as	as	IN
cord-306424-gf0bglm0	56	37	it	-PRON-	PRP
cord-306424-gf0bglm0	56	38	contributes	contribute	VBZ
cord-306424-gf0bglm0	56	39	to	to	IN
cord-306424-gf0bglm0	56	40	an	an	DT
cord-306424-gf0bglm0	56	41	antiviral	antiviral	JJ
cord-306424-gf0bglm0	56	42	state	state	NN
cord-306424-gf0bglm0	56	43	in	in	IN
cord-306424-gf0bglm0	56	44	both	both	CC
cord-306424-gf0bglm0	56	45	the	the	DT
cord-306424-gf0bglm0	56	46	infected	infected	JJ
cord-306424-gf0bglm0	56	47	host	host	NN
cord-306424-gf0bglm0	56	48	cell	cell	NN
cord-306424-gf0bglm0	56	49	and	and	CC
cord-306424-gf0bglm0	56	50	the	the	DT
cord-306424-gf0bglm0	56	51	(	(	-LRB-
cord-306424-gf0bglm0	56	52	un)infected	un)infecte	VBN
cord-306424-gf0bglm0	56	53	surrounding	surround	VBG
cord-306424-gf0bglm0	56	54	cells	cell	NNS
cord-306424-gf0bglm0	56	55	.	.	.
cord-306424-gf0bglm0	57	1	In	in	IN
cord-306424-gf0bglm0	57	2	addition	addition	NN
cord-306424-gf0bglm0	57	3	,	,	,
cord-306424-gf0bglm0	57	4	IFNs	ifn	NNS
cord-306424-gf0bglm0	57	5	play	play	VBP
cord-306424-gf0bglm0	57	6	an	an	DT
cord-306424-gf0bglm0	57	7	essential	essential	JJ
cord-306424-gf0bglm0	57	8	role	role	NN
cord-306424-gf0bglm0	57	9	in	in	IN
cord-306424-gf0bglm0	57	10	coordinating	coordinate	VBG
cord-306424-gf0bglm0	57	11	the	the	DT
cord-306424-gf0bglm0	57	12	antiviral	antiviral	JJ
cord-306424-gf0bglm0	57	13	adaptive	adaptive	JJ
cord-306424-gf0bglm0	57	14	immune	immune	JJ
cord-306424-gf0bglm0	57	15	response	response	NN
cord-306424-gf0bglm0	57	16	,	,	,
cord-306424-gf0bglm0	57	17	which	which	WDT
cord-306424-gf0bglm0	57	18	has	have	VBZ
cord-306424-gf0bglm0	57	19	been	be	VBN
cord-306424-gf0bglm0	57	20	reviewed	review	VBN
cord-306424-gf0bglm0	57	21	elsewhere	elsewhere	RB
cord-306424-gf0bglm0	57	22	[	[	-LRB-
cord-306424-gf0bglm0	57	23	35	35	CD
cord-306424-gf0bglm0	57	24	]	]	-RRB-
cord-306424-gf0bglm0	57	25	.	.	.
cord-306424-gf0bglm0	58	1	Three	three	CD
cord-306424-gf0bglm0	58	2	types	type	NNS
cord-306424-gf0bglm0	58	3	of	of	IN
cord-306424-gf0bglm0	58	4	IFNs	ifn	NNS
cord-306424-gf0bglm0	58	5	have	have	VBP
cord-306424-gf0bglm0	58	6	been	be	VBN
cord-306424-gf0bglm0	58	7	described	describe	VBN
cord-306424-gf0bglm0	58	8	.	.	.
cord-306424-gf0bglm0	59	1	Type	type	NN
cord-306424-gf0bglm0	59	2	I	-PRON-	PRP
cord-306424-gf0bglm0	59	3	IFNs	ifn	NNS
cord-306424-gf0bglm0	59	4	consist	consist	VBP
cord-306424-gf0bglm0	59	5	of	of	IN
cord-306424-gf0bglm0	59	6	13	13	CD
cord-306424-gf0bglm0	59	7	subtypes	subtype	NNS
cord-306424-gf0bglm0	59	8	of	of	IN
cord-306424-gf0bglm0	59	9	IFNa	IFNa	NNS
cord-306424-gf0bglm0	59	10	and	and	CC
cord-306424-gf0bglm0	59	11	a	a	DT
cord-306424-gf0bglm0	59	12	single	single	JJ
cord-306424-gf0bglm0	59	13	subtype	subtype	NN
cord-306424-gf0bglm0	59	14	of	of	IN
cord-306424-gf0bglm0	59	15	IFN	IFN	NNP
cord-306424-gf0bglm0	59	16	-	-	HYPH
cord-306424-gf0bglm0	59	17	b	b	NNP
cord-306424-gf0bglm0	59	18	,	,	,
cord-306424-gf0bglm0	59	19	IFN	IFN	NNP
cord-306424-gf0bglm0	59	20	-	-	HYPH
cord-306424-gf0bglm0	59	21	d	d	NNP
cord-306424-gf0bglm0	59	22	,	,	,
cord-306424-gf0bglm0	59	23	IFN	IFN	NNP
cord-306424-gf0bglm0	59	24	-	-	HYPH
cord-306424-gf0bglm0	59	25	e	e	NNP
cord-306424-gf0bglm0	59	26	,	,	,
cord-306424-gf0bglm0	59	27	IFN	IFN	NNP
cord-306424-gf0bglm0	59	28	-	-	HYPH
cord-306424-gf0bglm0	59	29	k	k	NNP
cord-306424-gf0bglm0	59	30	,	,	,
cord-306424-gf0bglm0	59	31	IFN	IFN	NNP
cord-306424-gf0bglm0	59	32	-	-	HYPH
cord-306424-gf0bglm0	59	33	t	t	NNP
cord-306424-gf0bglm0	59	34	and	and	CC
cord-306424-gf0bglm0	59	35	IFNv	IFNv	NNP
cord-306424-gf0bglm0	59	36	.	.	.
cord-306424-gf0bglm0	60	1	Type	type	NN
cord-306424-gf0bglm0	60	2	II	II	NNP
cord-306424-gf0bglm0	60	3	IFN	IFN	NNP
cord-306424-gf0bglm0	60	4	only	only	RB
cord-306424-gf0bglm0	60	5	contains	contain	VBZ
cord-306424-gf0bglm0	60	6	one	one	CD
cord-306424-gf0bglm0	60	7	subtype	subtype	NN
cord-306424-gf0bglm0	60	8	of	of	IN
cord-306424-gf0bglm0	60	9	IFN	IFN	NNP
cord-306424-gf0bglm0	60	10	-	-	HYPH
cord-306424-gf0bglm0	60	11	g	g	NNP
cord-306424-gf0bglm0	60	12	,	,	,
cord-306424-gf0bglm0	60	13	and	and	CC
cord-306424-gf0bglm0	60	14	type	type	NN
cord-306424-gf0bglm0	60	15	III	iii	CD
cord-306424-gf0bglm0	60	16	IFNs	ifn	NNS
cord-306424-gf0bglm0	60	17	comprise	comprise	NN
cord-306424-gf0bglm0	60	18	of	of	IN
cord-306424-gf0bglm0	60	19	IFN	IFN	NNP
cord-306424-gf0bglm0	60	20	-	-	HYPH
cord-306424-gf0bglm0	60	21	l1	l1	NNP
cord-306424-gf0bglm0	60	22	through	through	IN
cord-306424-gf0bglm0	60	23	Àl4	àl4	NN
cord-306424-gf0bglm0	60	24	.	.	.
cord-306424-gf0bglm0	61	1	Whereas	whereas	IN
cord-306424-gf0bglm0	61	2	it	-PRON-	PRP
cord-306424-gf0bglm0	61	3	is	be	VBZ
cord-306424-gf0bglm0	61	4	known	know	VBN
cord-306424-gf0bglm0	61	5	that	that	IN
cord-306424-gf0bglm0	61	6	most	most	JJS
cord-306424-gf0bglm0	61	7	cell	cell	NN
cord-306424-gf0bglm0	61	8	types	type	NNS
cord-306424-gf0bglm0	61	9	produce	produce	VBP
cord-306424-gf0bglm0	61	10	type	type	NN
cord-306424-gf0bglm0	61	11	I	-PRON-	PRP
cord-306424-gf0bglm0	61	12	IFNs	ifns	VBP
cord-306424-gf0bglm0	61	13	in	in	IN
cord-306424-gf0bglm0	61	14	response	response	NN
cord-306424-gf0bglm0	61	15	to	to	IN
cord-306424-gf0bglm0	61	16	viral	viral	JJ
cord-306424-gf0bglm0	61	17	infection	infection	NN
cord-306424-gf0bglm0	61	18	,	,	,
cord-306424-gf0bglm0	61	19	type	type	NN
cord-306424-gf0bglm0	61	20	II	II	NNP
cord-306424-gf0bglm0	61	21	IFNs	ifn	NNS
cord-306424-gf0bglm0	61	22	are	be	VBP
cord-306424-gf0bglm0	61	23	only	only	RB
cord-306424-gf0bglm0	61	24	produced	produce	VBN
cord-306424-gf0bglm0	61	25	after	after	IN
cord-306424-gf0bglm0	61	26	antigenic	antigenic	JJ
cord-306424-gf0bglm0	61	27	stimulation	stimulation	NN
cord-306424-gf0bglm0	61	28	of	of	IN
cord-306424-gf0bglm0	61	29	an	an	DT
cord-306424-gf0bglm0	61	30	expanding	expand	VBG
cord-306424-gf0bglm0	61	31	group	group	NN
cord-306424-gf0bglm0	61	32	of	of	IN
cord-306424-gf0bglm0	61	33	certain	certain	JJ
cord-306424-gf0bglm0	61	34	immune	immune	JJ
cord-306424-gf0bglm0	61	35	cells	cell	NNS
cord-306424-gf0bglm0	61	36	,	,	,
cord-306424-gf0bglm0	61	37	including	include	VBG
cord-306424-gf0bglm0	61	38	T	t	NN
cord-306424-gf0bglm0	61	39	-	-	HYPH
cord-306424-gf0bglm0	61	40	cells	cell	NNS
cord-306424-gf0bglm0	61	41	,	,	,
cord-306424-gf0bglm0	61	42	natural	natural	JJ
cord-306424-gf0bglm0	61	43	killer	killer	NN
cord-306424-gf0bglm0	61	44	cells	cell	NNS
cord-306424-gf0bglm0	61	45	,	,	,
cord-306424-gf0bglm0	61	46	dendritic	dendritic	JJ
cord-306424-gf0bglm0	61	47	cells	cell	NNS
cord-306424-gf0bglm0	61	48	,	,	,
cord-306424-gf0bglm0	61	49	and	and	CC
cord-306424-gf0bglm0	61	50	macrophages	macrophage	NNS
cord-306424-gf0bglm0	61	51	[	[	-LRB-
cord-306424-gf0bglm0	61	52	36	36	CD
cord-306424-gf0bglm0	61	53	,	,	,
cord-306424-gf0bglm0	61	54	37	37	CD
cord-306424-gf0bglm0	61	55	]	]	-RRB-
cord-306424-gf0bglm0	61	56	.	.	.
cord-306424-gf0bglm0	62	1	In	in	IN
cord-306424-gf0bglm0	62	2	contrast	contrast	NN
cord-306424-gf0bglm0	62	3	,	,	,
cord-306424-gf0bglm0	62	4	little	little	JJ
cord-306424-gf0bglm0	62	5	is	be	VBZ
cord-306424-gf0bglm0	62	6	known	know	VBN
cord-306424-gf0bglm0	62	7	about	about	IN
cord-306424-gf0bglm0	62	8	type	type	NN
cord-306424-gf0bglm0	62	9	III	III	NNP
cord-306424-gf0bglm0	62	10	IFN	IFN	NNP
cord-306424-gf0bglm0	62	11	production	production	NN
cord-306424-gf0bglm0	62	12	in	in	IN
cord-306424-gf0bglm0	62	13	vitro	vitro	FW
cord-306424-gf0bglm0	62	14	and	and	CC
cord-306424-gf0bglm0	62	15	in	in	IN
cord-306424-gf0bglm0	62	16	vivo	vivo	NNP
cord-306424-gf0bglm0	62	17	,	,	,
cord-306424-gf0bglm0	62	18	although	although	IN
cord-306424-gf0bglm0	62	19	it	-PRON-	PRP
cord-306424-gf0bglm0	62	20	is	be	VBZ
cord-306424-gf0bglm0	62	21	believed	believe	VBN
cord-306424-gf0bglm0	62	22	that	that	IN
cord-306424-gf0bglm0	62	23	most	most	JJS
cord-306424-gf0bglm0	62	24	cell	cell	NN
cord-306424-gf0bglm0	62	25	types	type	NNS
cord-306424-gf0bglm0	62	26	that	that	WDT
cord-306424-gf0bglm0	62	27	produce	produce	VBP
cord-306424-gf0bglm0	62	28	type	type	NN
cord-306424-gf0bglm0	62	29	I	-PRON-	PRP
cord-306424-gf0bglm0	62	30	IFNs	ifn	NNS
cord-306424-gf0bglm0	62	31	are	be	VBP
cord-306424-gf0bglm0	62	32	capable	capable	JJ
cord-306424-gf0bglm0	62	33	of	of	IN
cord-306424-gf0bglm0	62	34	producing	produce	VBG
cord-306424-gf0bglm0	62	35	type	type	NN
cord-306424-gf0bglm0	62	36	III	iii	CD
cord-306424-gf0bglm0	62	37	IFNs	ifn	NNS
cord-306424-gf0bglm0	62	38	as	as	RB
cord-306424-gf0bglm0	62	39	well	well	RB
cord-306424-gf0bglm0	62	40	[	[	-LRB-
cord-306424-gf0bglm0	62	41	38	38	CD
cord-306424-gf0bglm0	62	42	]	]	-RRB-
cord-306424-gf0bglm0	62	43	.	.	.
cord-306424-gf0bglm0	63	1	Most	Most	JJS
cord-306424-gf0bglm0	63	2	cells	cell	NNS
cord-306424-gf0bglm0	63	3	are	be	VBP
cord-306424-gf0bglm0	63	4	able	able	JJ
cord-306424-gf0bglm0	63	5	to	to	TO
cord-306424-gf0bglm0	63	6	respond	respond	VB
cord-306424-gf0bglm0	63	7	to	to	IN
cord-306424-gf0bglm0	63	8	IFN	IFN	NNP
cord-306424-gf0bglm0	63	9	-	-	HYPH
cord-306424-gf0bglm0	63	10	I	I	NNP
cord-306424-gf0bglm0	63	11	and	and	CC
cord-306424-gf0bglm0	63	12	ÀII	ÀII	NNP
cord-306424-gf0bglm0	63	13	,	,	,
cord-306424-gf0bglm0	63	14	whereas	whereas	IN
cord-306424-gf0bglm0	63	15	IFN	IFN	NNP
cord-306424-gf0bglm0	63	16	-	-	HYPH
cord-306424-gf0bglm0	63	17	III	III	NNP
cord-306424-gf0bglm0	63	18	receptors	receptor	NNS
cord-306424-gf0bglm0	63	19	are	be	VBP
cord-306424-gf0bglm0	63	20	mainly	mainly	RB
cord-306424-gf0bglm0	63	21	found	find	VBN
cord-306424-gf0bglm0	63	22	on	on	IN
cord-306424-gf0bglm0	63	23	epithelial	epithelial	JJ
cord-306424-gf0bglm0	63	24	cells	cell	NNS
cord-306424-gf0bglm0	63	25	[	[	-LRB-
cord-306424-gf0bglm0	63	26	39	39	CD
cord-306424-gf0bglm0	63	27	]	]	-RRB-
cord-306424-gf0bglm0	63	28	.	.	.
cord-306424-gf0bglm0	64	1	The	the	DT
cord-306424-gf0bglm0	64	2	protective	protective	JJ
cord-306424-gf0bglm0	64	3	role	role	NN
cord-306424-gf0bglm0	64	4	of	of	IN
cord-306424-gf0bglm0	64	5	IFNs	ifn	NNS
cord-306424-gf0bglm0	64	6	during	during	IN
cord-306424-gf0bglm0	64	7	viral	viral	JJ
cord-306424-gf0bglm0	64	8	infection	infection	NN
cord-306424-gf0bglm0	64	9	is	be	VBZ
cord-306424-gf0bglm0	64	10	for	for	IN
cord-306424-gf0bglm0	64	11	example	example	NN
cord-306424-gf0bglm0	64	12	illustrated	illustrate	VBN
cord-306424-gf0bglm0	64	13	by	by	IN
cord-306424-gf0bglm0	64	14	inhibitory	inhibitory	JJ
cord-306424-gf0bglm0	64	15	effects	effect	NNS
cord-306424-gf0bglm0	64	16	of	of	IN
cord-306424-gf0bglm0	64	17	IFNa	IFNa	NNS
cord-306424-gf0bglm0	64	18	,	,	,
cord-306424-gf0bglm0	64	19	IFN	IFN	NNP
cord-306424-gf0bglm0	64	20	-	-	HYPH
cord-306424-gf0bglm0	64	21	b	b	NNP
cord-306424-gf0bglm0	64	22	,	,	,
cord-306424-gf0bglm0	64	23	and	and	CC
cord-306424-gf0bglm0	64	24	IFN	IFN	NNP
cord-306424-gf0bglm0	64	25	-	-	HYPH
cord-306424-gf0bglm0	64	26	g	g	NNP
cord-306424-gf0bglm0	64	27	on	on	IN
cord-306424-gf0bglm0	64	28	SARS	SARS	NNP
cord-306424-gf0bglm0	64	29	-	-	HYPH
cord-306424-gf0bglm0	64	30	CoV	cov	NN
cord-306424-gf0bglm0	64	31	replication	replication	NN
cord-306424-gf0bglm0	64	32	in	in	IN
cord-306424-gf0bglm0	64	33	vitro	vitro	FW
cord-306424-gf0bglm0	64	34	and	and	CC
cord-306424-gf0bglm0	64	35	in	in	IN
cord-306424-gf0bglm0	64	36	vivo	vivo	NNP
cord-306424-gf0bglm0	64	37	[	[	-LRB-
cord-306424-gf0bglm0	64	38	40	40	CD
cord-306424-gf0bglm0	64	39	]	]	-RRB-
cord-306424-gf0bglm0	64	40	[	[	-LRB-
cord-306424-gf0bglm0	64	41	41	41	CD
cord-306424-gf0bglm0	64	42	]	]	-RRB-
cord-306424-gf0bglm0	64	43	[	[	-LRB-
cord-306424-gf0bglm0	64	44	42	42	CD
cord-306424-gf0bglm0	64	45	]	]	-RRB-
cord-306424-gf0bglm0	64	46	[	[	-LRB-
cord-306424-gf0bglm0	64	47	43	43	CD
cord-306424-gf0bglm0	64	48	]	]	-RRB-
cord-306424-gf0bglm0	64	49	.	.	.
cord-306424-gf0bglm0	65	1	Importantly	importantly	RB
cord-306424-gf0bglm0	65	2	,	,	,
cord-306424-gf0bglm0	65	3	correct	correct	JJ
cord-306424-gf0bglm0	65	4	timing	timing	NN
cord-306424-gf0bglm0	65	5	and	and	CC
cord-306424-gf0bglm0	65	6	amount	amount	NN
cord-306424-gf0bglm0	65	7	of	of	IN
cord-306424-gf0bglm0	65	8	IFN	IFN	NNP
cord-306424-gf0bglm0	65	9	and	and	CC
cord-306424-gf0bglm0	65	10	subsequent	subsequent	JJ
cord-306424-gf0bglm0	65	11	pro	pro	JJ
cord-306424-gf0bglm0	65	12	-	-	JJ
cord-306424-gf0bglm0	65	13	inflammatory	inflammatory	JJ
cord-306424-gf0bglm0	65	14	cytokine	cytokine	NN
cord-306424-gf0bglm0	65	15	expression	expression	NN
cord-306424-gf0bglm0	65	16	is	be	VBZ
cord-306424-gf0bglm0	65	17	essential	essential	JJ
cord-306424-gf0bglm0	65	18	for	for	IN
cord-306424-gf0bglm0	65	19	an	an	DT
cord-306424-gf0bglm0	65	20	effective	effective	JJ
cord-306424-gf0bglm0	65	21	antiviral	antiviral	JJ
cord-306424-gf0bglm0	65	22	immune	immune	JJ
cord-306424-gf0bglm0	65	23	response	response	NN
cord-306424-gf0bglm0	65	24	,	,	,
cord-306424-gf0bglm0	65	25	as	as	IN
cord-306424-gf0bglm0	65	26	delayed	delay	VBN
cord-306424-gf0bglm0	65	27	and/or	and/or	CC
cord-306424-gf0bglm0	65	28	elevated	elevated	JJ
cord-306424-gf0bglm0	65	29	induction	induction	NN
cord-306424-gf0bglm0	65	30	may	may	MD
cord-306424-gf0bglm0	65	31	stimulate	stimulate	VB
cord-306424-gf0bglm0	65	32	immunopathological	immunopathological	JJ
cord-306424-gf0bglm0	65	33	outcomes	outcome	NNS
cord-306424-gf0bglm0	65	34	[	[	-LRB-
cord-306424-gf0bglm0	65	35	35	35	CD
cord-306424-gf0bglm0	65	36	]	]	-RRB-
cord-306424-gf0bglm0	65	37	.	.	.
cord-306424-gf0bglm0	66	1	Below	below	IN
cord-306424-gf0bglm0	66	2	we	-PRON-	PRP
cord-306424-gf0bglm0	66	3	will	will	MD
cord-306424-gf0bglm0	66	4	focus	focus	VB
cord-306424-gf0bglm0	66	5	on	on	IN
cord-306424-gf0bglm0	66	6	the	the	DT
cord-306424-gf0bglm0	66	7	interactions	interaction	NNS
cord-306424-gf0bglm0	66	8	of	of	IN
cord-306424-gf0bglm0	66	9	the	the	DT
cord-306424-gf0bglm0	66	10	innate	innate	JJ
cord-306424-gf0bglm0	66	11	immune	immune	JJ
cord-306424-gf0bglm0	66	12	system	system	NN
cord-306424-gf0bglm0	66	13	with	with	IN
cord-306424-gf0bglm0	66	14	the	the	DT
cord-306424-gf0bglm0	66	15	RNA	RNA	NNP
cord-306424-gf0bglm0	66	16	replication	replication	NN
cord-306424-gf0bglm0	66	17	stages	stage	NNS
cord-306424-gf0bglm0	66	18	of	of	IN
cord-306424-gf0bglm0	66	19	+	+	CD
cord-306424-gf0bglm0	66	20	RNA	RNA	NNP
cord-306424-gf0bglm0	66	21	virus	virus	NN
cord-306424-gf0bglm0	66	22	infection	infection	NN
cord-306424-gf0bglm0	66	23	,	,	,
cord-306424-gf0bglm0	66	24	including	include	VBG
cord-306424-gf0bglm0	66	25	exposure	exposure	NN
cord-306424-gf0bglm0	66	26	of	of	IN
cord-306424-gf0bglm0	66	27	viral	viral	JJ
cord-306424-gf0bglm0	66	28	RNA	RNA	NNP
cord-306424-gf0bglm0	66	29	to	to	IN
cord-306424-gf0bglm0	66	30	the	the	DT
cord-306424-gf0bglm0	66	31	cytosol	cytosol	NN
cord-306424-gf0bglm0	66	32	after	after	IN
cord-306424-gf0bglm0	66	33	the	the	DT
cord-306424-gf0bglm0	66	34	unpacking	unpacking	NN
cord-306424-gf0bglm0	66	35	of	of	IN
cord-306424-gf0bglm0	66	36	virus	virus	NN
cord-306424-gf0bglm0	66	37	particles	particle	NNS
cord-306424-gf0bglm0	66	38	,	,	,
cord-306424-gf0bglm0	66	39	and	and	CC
cord-306424-gf0bglm0	66	40	formation	formation	NN
cord-306424-gf0bglm0	66	41	of	of	IN
cord-306424-gf0bglm0	66	42	ROs	ROs	NNP
cord-306424-gf0bglm0	66	43	by	by	IN
cord-306424-gf0bglm0	66	44	the	the	DT
cord-306424-gf0bglm0	66	45	virus	virus	NN
cord-306424-gf0bglm0	66	46	.	.	.
cord-306424-gf0bglm0	67	1	We	-PRON-	PRP
cord-306424-gf0bglm0	67	2	will	will	MD
cord-306424-gf0bglm0	67	3	also	also	RB
cord-306424-gf0bglm0	67	4	discuss	discuss	VB
cord-306424-gf0bglm0	67	5	examples	example	NNS
cord-306424-gf0bglm0	67	6	of	of	IN
cord-306424-gf0bglm0	67	7	viral	viral	JJ
cord-306424-gf0bglm0	67	8	evasion	evasion	NN
cord-306424-gf0bglm0	67	9	surrounding	surround	VBG
cord-306424-gf0bglm0	67	10	these	these	DT
cord-306424-gf0bglm0	67	11	processes	process	NNS
cord-306424-gf0bglm0	67	12	.	.	.
cord-306424-gf0bglm0	68	1	IFN	IFN	NNP
cord-306424-gf0bglm0	68	2	-	-	HYPH
cord-306424-gf0bglm0	68	3	I	I	NNP
cord-306424-gf0bglm0	68	4	and	and	CC
cord-306424-gf0bglm0	68	5	-III	-III	NFP
cord-306424-gf0bglm0	68	6	production	production	NN
cord-306424-gf0bglm0	68	7	is	be	VBZ
cord-306424-gf0bglm0	68	8	triggered	trigger	VBN
cord-306424-gf0bglm0	68	9	after	after	IN
cord-306424-gf0bglm0	68	10	host	host	NN
cord-306424-gf0bglm0	68	11	cells	cell	NNS
cord-306424-gf0bglm0	68	12	detect	detect	VBP
cord-306424-gf0bglm0	68	13	viral	viral	JJ
cord-306424-gf0bglm0	68	14	RNA	RNA	NNP
cord-306424-gf0bglm0	68	15	,	,	,
cord-306424-gf0bglm0	68	16	primarily	primarily	RB
cord-306424-gf0bglm0	68	17	using	use	VBG
cord-306424-gf0bglm0	68	18	cytosolic	cytosolic	JJ
cord-306424-gf0bglm0	68	19	RIG	rig	NN
cord-306424-gf0bglm0	68	20	-	-	:
cord-306424-gf0bglm0	68	21	I	-PRON-	PRP
cord-306424-gf0bglm0	68	22	like	like	IN
cord-306424-gf0bglm0	68	23	Receptors	receptor	NNS
cord-306424-gf0bglm0	68	24	(	(	-LRB-
cord-306424-gf0bglm0	68	25	RLRs	rlr	NNS
cord-306424-gf0bglm0	68	26	)	)	-RRB-
cord-306424-gf0bglm0	68	27	and	and	CC
cord-306424-gf0bglm0	68	28	membrane	membrane	NN
cord-306424-gf0bglm0	68	29	-	-	HYPH
cord-306424-gf0bglm0	68	30	bound	bind	VBN
cord-306424-gf0bglm0	68	31	Toll	toll	NN
cord-306424-gf0bglm0	68	32	-	-	HYPH
cord-306424-gf0bglm0	68	33	like	like	JJ
cord-306424-gf0bglm0	68	34	receptors	receptor	NNS
cord-306424-gf0bglm0	68	35	(	(	-LRB-
cord-306424-gf0bglm0	68	36	TLRs	TLRs	NNP
cord-306424-gf0bglm0	68	37	)	)	-RRB-
cord-306424-gf0bglm0	68	38	.	.	.
cord-306424-gf0bglm0	69	1	RLRs	RLRs	NNP
cord-306424-gf0bglm0	69	2	retinoic	retinoic	NNP
cord-306424-gf0bglm0	69	3	acidinducible	acidinducible	NNP
cord-306424-gf0bglm0	69	4	gene	gene	NN
cord-306424-gf0bglm0	70	1	I	-PRON-	PRP
cord-306424-gf0bglm0	71	1	(	(	-LRB-
cord-306424-gf0bglm0	71	2	RIG	rig	NN
cord-306424-gf0bglm0	71	3	-	-	:
cord-306424-gf0bglm0	71	4	I	i	NN
cord-306424-gf0bglm0	71	5	)	)	-RRB-
cord-306424-gf0bglm0	71	6	and	and	CC
cord-306424-gf0bglm0	71	7	melanoma	melanoma	NN
cord-306424-gf0bglm0	71	8	differentiation	differentiation	NN
cord-306424-gf0bglm0	71	9	associated	associate	VBD
cord-306424-gf0bglm0	71	10	factor	factor	NN
cord-306424-gf0bglm0	71	11	5	5	CD
cord-306424-gf0bglm0	72	1	(	(	-LRB-
cord-306424-gf0bglm0	72	2	MDA5	MDA5	NNP
cord-306424-gf0bglm0	72	3	)	)	-RRB-
cord-306424-gf0bglm0	72	4	have	have	VBP
cord-306424-gf0bglm0	72	5	been	be	VBN
cord-306424-gf0bglm0	72	6	studied	study	VBN
cord-306424-gf0bglm0	72	7	extensively	extensively	RB
cord-306424-gf0bglm0	72	8	(	(	-LRB-
cord-306424-gf0bglm0	72	9	reviewed	review	VBN
cord-306424-gf0bglm0	72	10	in	in	IN
cord-306424-gf0bglm0	72	11	[	[	-LRB-
cord-306424-gf0bglm0	72	12	44	44	CD
cord-306424-gf0bglm0	72	13	,	,	,
cord-306424-gf0bglm0	72	14	45	45	CD
cord-306424-gf0bglm0	72	15	]	]	-RRB-
cord-306424-gf0bglm0	72	16	)	)	-RRB-
cord-306424-gf0bglm0	72	17	.	.	.
cord-306424-gf0bglm0	73	1	Besides	besides	IN
cord-306424-gf0bglm0	73	2	their	-PRON-	PRP$
cord-306424-gf0bglm0	73	3	role	role	NN
cord-306424-gf0bglm0	73	4	in	in	IN
cord-306424-gf0bglm0	73	5	RNA	RNA	NNP
cord-306424-gf0bglm0	73	6	metabolism	metabolism	NN
cord-306424-gf0bglm0	73	7	,	,	,
cord-306424-gf0bglm0	73	8	RIG	rig	NN
cord-306424-gf0bglm0	73	9	-	-	:
cord-306424-gf0bglm0	73	10	I	I	NNP
cord-306424-gf0bglm0	73	11	and	and	CC
cord-306424-gf0bglm0	73	12	MDA5	MDA5	NNP
cord-306424-gf0bglm0	73	13	recognize	recognize	VBP
cord-306424-gf0bglm0	73	14	viral	viral	JJ
cord-306424-gf0bglm0	73	15	RNA	RNA	NNP
cord-306424-gf0bglm0	73	16	by	by	IN
cord-306424-gf0bglm0	73	17	binding	bind	VBG
cord-306424-gf0bglm0	73	18	phosphorylated	phosphorylate	VBN
cord-306424-gf0bglm0	73	19	5	5	CD
cord-306424-gf0bglm0	73	20	0	0	CD
cord-306424-gf0bglm0	73	21	termini	terminus	NNS
cord-306424-gf0bglm0	73	22	(	(	-LRB-
cord-306424-gf0bglm0	73	23	5	5	CD
cord-306424-gf0bglm0	73	24	0	0	CD
cord-306424-gf0bglm0	73	25	ppp	ppp	NNP
cord-306424-gf0bglm0	73	26	-	-	HYPH
cord-306424-gf0bglm0	73	27	RNA	RNA	NNP
cord-306424-gf0bglm0	73	28	)	)	-RRB-
cord-306424-gf0bglm0	73	29	in	in	IN
cord-306424-gf0bglm0	73	30	combination	combination	NN
cord-306424-gf0bglm0	73	31	with	with	IN
cord-306424-gf0bglm0	73	32	dsRNA	dsrna	NN
cord-306424-gf0bglm0	73	33	or	or	CC
cord-306424-gf0bglm0	73	34	ssRNA	ssrna	NN
cord-306424-gf0bglm0	73	35	motifs	motif	NNS
cord-306424-gf0bglm0	73	36	.	.	.
cord-306424-gf0bglm0	74	1	Detection	detection	NN
cord-306424-gf0bglm0	74	2	of	of	IN
cord-306424-gf0bglm0	74	3	viral	viral	JJ
cord-306424-gf0bglm0	74	4	RNA	RNA	NNP
cord-306424-gf0bglm0	74	5	activates	activate	VBZ
cord-306424-gf0bglm0	74	6	RLRs	rlr	NNS
cord-306424-gf0bglm0	74	7	and	and	CC
cord-306424-gf0bglm0	74	8	triggers	trigger	VBZ
cord-306424-gf0bglm0	74	9	downstream	downstream	RB
cord-306424-gf0bglm0	74	10	signaling	signal	VBG
cord-306424-gf0bglm0	74	11	through	through	IN
cord-306424-gf0bglm0	74	12	the	the	DT
cord-306424-gf0bglm0	74	13	mitochondrial	mitochondrial	JJ
cord-306424-gf0bglm0	74	14	antiviral	antiviral	JJ
cord-306424-gf0bglm0	74	15	signaling	signaling	NN
cord-306424-gf0bglm0	74	16	(	(	-LRB-
cord-306424-gf0bglm0	74	17	MAVS	MAVS	NNP
cord-306424-gf0bglm0	74	18	)	)	-RRB-
cord-306424-gf0bglm0	74	19	adaptor	adaptor	NN
cord-306424-gf0bglm0	74	20	,	,	,
cord-306424-gf0bglm0	74	21	which	which	WDT
cord-306424-gf0bglm0	74	22	is	be	VBZ
cord-306424-gf0bglm0	74	23	localized	localize	VBN
cord-306424-gf0bglm0	74	24	on	on	IN
cord-306424-gf0bglm0	74	25	the	the	DT
cord-306424-gf0bglm0	74	26	outer	outer	JJ
cord-306424-gf0bglm0	74	27	mitochondrial	mitochondrial	NN
cord-306424-gf0bglm0	74	28	membrane	membrane	NN
cord-306424-gf0bglm0	74	29	[	[	-LRB-
cord-306424-gf0bglm0	74	30	46	46	CD
cord-306424-gf0bglm0	74	31	]	]	-RRB-
cord-306424-gf0bglm0	74	32	[	[	-LRB-
cord-306424-gf0bglm0	74	33	47	47	CD
cord-306424-gf0bglm0	74	34	]	]	-RRB-
cord-306424-gf0bglm0	75	1	[	[	-LRB-
cord-306424-gf0bglm0	75	2	48	48	CD
cord-306424-gf0bglm0	75	3	]	]	-RRB-
cord-306424-gf0bglm0	75	4	[	[	-LRB-
cord-306424-gf0bglm0	75	5	49	49	CD
cord-306424-gf0bglm0	75	6	]	]	-RRB-
cord-306424-gf0bglm0	75	7	.	.	.
cord-306424-gf0bglm0	76	1	The	the	DT
cord-306424-gf0bglm0	76	2	importance	importance	NN
cord-306424-gf0bglm0	76	3	of	of	IN
cord-306424-gf0bglm0	76	4	MAVS	MAVS	NNPS
cord-306424-gf0bglm0	76	5	is	be	VBZ
cord-306424-gf0bglm0	76	6	underscored	underscore	VBN
cord-306424-gf0bglm0	76	7	by	by	IN
cord-306424-gf0bglm0	76	8	the	the	DT
cord-306424-gf0bglm0	76	9	observation	observation	NN
cord-306424-gf0bglm0	76	10	that	that	IN
cord-306424-gf0bglm0	76	11	silencing	silence	VBG
cord-306424-gf0bglm0	76	12	of	of	IN
cord-306424-gf0bglm0	76	13	this	this	DT
cord-306424-gf0bglm0	76	14	protein	protein	NN
cord-306424-gf0bglm0	76	15	by	by	IN
cord-306424-gf0bglm0	76	16	RNA	RNA	NNP
cord-306424-gf0bglm0	76	17	interference	interference	NN
cord-306424-gf0bglm0	76	18	abolishes	abolish	VBZ
cord-306424-gf0bglm0	76	19	expression	expression	NN
cord-306424-gf0bglm0	76	20	of	of	IN
cord-306424-gf0bglm0	76	21	type	type	NN
cord-306424-gf0bglm0	76	22	I	-PRON-	PRP
cord-306424-gf0bglm0	76	23	IFNs	ifns	VBP
cord-306424-gf0bglm0	76	24	[	[	-LRB-
cord-306424-gf0bglm0	76	25	46	46	CD
cord-306424-gf0bglm0	76	26	]	]	-RRB-
cord-306424-gf0bglm0	76	27	.	.	.
cord-306424-gf0bglm0	77	1	Subsequently	subsequently	RB
cord-306424-gf0bglm0	77	2	,	,	,
cord-306424-gf0bglm0	77	3	MAVS	MAVS	NNP
cord-306424-gf0bglm0	77	4	recruits	recruit	VBZ
cord-306424-gf0bglm0	77	5	various	various	JJ
cord-306424-gf0bglm0	77	6	adaptor	adaptor	NN
cord-306424-gf0bglm0	77	7	molecules	molecule	NNS
cord-306424-gf0bglm0	77	8	such	such	JJ
cord-306424-gf0bglm0	77	9	as	as	IN
cord-306424-gf0bglm0	77	10	Stimulator	Stimulator	NNP
cord-306424-gf0bglm0	77	11	of	of	IN
cord-306424-gf0bglm0	77	12	interferon	interferon	NN
cord-306424-gf0bglm0	77	13	genes	gene	NNS
cord-306424-gf0bglm0	77	14	(	(	-LRB-
cord-306424-gf0bglm0	77	15	STING	sting	VB
cord-306424-gf0bglm0	77	16	)	)	-RRB-
cord-306424-gf0bglm0	77	17	and	and	CC
cord-306424-gf0bglm0	77	18	TNF	TNF	NNP
cord-306424-gf0bglm0	77	19	receptor	receptor	NN
cord-306424-gf0bglm0	77	20	-	-	HYPH
cord-306424-gf0bglm0	77	21	associated	associate	VBN
cord-306424-gf0bglm0	77	22	factors	factor	NNS
cord-306424-gf0bglm0	77	23	,	,	,
cord-306424-gf0bglm0	77	24	resulting	result	VBG
cord-306424-gf0bglm0	77	25	in	in	IN
cord-306424-gf0bglm0	77	26	the	the	DT
cord-306424-gf0bglm0	77	27	formation	formation	NN
cord-306424-gf0bglm0	77	28	of	of	IN
cord-306424-gf0bglm0	77	29	large	large	JJ
cord-306424-gf0bglm0	77	30	signaling	signal	VBG
cord-306424-gf0bglm0	77	31	complexes	complex	NNS
cord-306424-gf0bglm0	77	32	[	[	-LRB-
cord-306424-gf0bglm0	77	33	50	50	CD
cord-306424-gf0bglm0	77	34	]	]	-RRB-
cord-306424-gf0bglm0	77	35	.	.	.
cord-306424-gf0bglm0	78	1	Ultimately	ultimately	RB
cord-306424-gf0bglm0	78	2	,	,	,
cord-306424-gf0bglm0	78	3	this	this	DT
cord-306424-gf0bglm0	78	4	leads	lead	VBZ
cord-306424-gf0bglm0	78	5	to	to	IN
cord-306424-gf0bglm0	78	6	activation	activation	NN
cord-306424-gf0bglm0	78	7	of	of	IN
cord-306424-gf0bglm0	78	8	kinase	kinase	NN
cord-306424-gf0bglm0	78	9	complexes	complex	NNS
cord-306424-gf0bglm0	78	10	IKKe	IKKe	NNP
cord-306424-gf0bglm0	78	11	/	/	SYM
cord-306424-gf0bglm0	78	12	TBK1	TBK1	NNP
cord-306424-gf0bglm0	78	13	and	and	CC
cord-306424-gf0bglm0	78	14	IKKa	IKKa	NNPS
cord-306424-gf0bglm0	78	15	/	/	SYM
cord-306424-gf0bglm0	78	16	IKKb	IKKb	NNP
cord-306424-gf0bglm0	78	17	/	/	SYM
cord-306424-gf0bglm0	78	18	IKKg	IKKg	NNS
cord-306424-gf0bglm0	78	19	,	,	,
cord-306424-gf0bglm0	78	20	resulting	result	VBG
cord-306424-gf0bglm0	78	21	in	in	IN
cord-306424-gf0bglm0	78	22	activation	activation	NN
cord-306424-gf0bglm0	78	23	of	of	IN
cord-306424-gf0bglm0	78	24	interferon	interferon	NN
cord-306424-gf0bglm0	78	25	regulating	regulate	VBG
cord-306424-gf0bglm0	78	26	factor	factor	NN
cord-306424-gf0bglm0	78	27	3	3	CD
cord-306424-gf0bglm0	78	28	(	(	-LRB-
cord-306424-gf0bglm0	78	29	IRF3	IRF3	NNP
cord-306424-gf0bglm0	78	30	)	)	-RRB-
cord-306424-gf0bglm0	78	31	,	,	,
cord-306424-gf0bglm0	78	32	7	7	CD
cord-306424-gf0bglm0	78	33	(	(	-LRB-
cord-306424-gf0bglm0	78	34	IRF7	IRF7	NNP
cord-306424-gf0bglm0	78	35	)	)	-RRB-
cord-306424-gf0bglm0	78	36	and	and	CC
cord-306424-gf0bglm0	78	37	NF	nf	NN
cord-306424-gf0bglm0	78	38	-	-	HYPH
cord-306424-gf0bglm0	78	39	k	k	NN
cord-306424-gf0bglm0	79	1	B.	B.	NNP
cord-306424-gf0bglm0	79	2	These	these	DT
cord-306424-gf0bglm0	79	3	transcription	transcription	NN
cord-306424-gf0bglm0	79	4	factors	factor	NNS
cord-306424-gf0bglm0	79	5	then	then	RB
cord-306424-gf0bglm0	79	6	translocate	translocate	VBP
cord-306424-gf0bglm0	79	7	to	to	IN
cord-306424-gf0bglm0	79	8	the	the	DT
cord-306424-gf0bglm0	79	9	nucleus	nucleus	NN
cord-306424-gf0bglm0	79	10	and	and	CC
cord-306424-gf0bglm0	79	11	initiate	initiate	VB
cord-306424-gf0bglm0	79	12	the	the	DT
cord-306424-gf0bglm0	79	13	expression	expression	NN
cord-306424-gf0bglm0	79	14	of	of	IN
cord-306424-gf0bglm0	79	15	IFNs	ifn	NNS
cord-306424-gf0bglm0	79	16	and	and	CC
cord-306424-gf0bglm0	79	17	pro	pro	JJ
cord-306424-gf0bglm0	79	18	-	-	JJ
cord-306424-gf0bglm0	79	19	inflammatory	inflammatory	JJ
cord-306424-gf0bglm0	79	20	cytokines	cytokine	NNS
cord-306424-gf0bglm0	79	21	.	.	.
cord-306424-gf0bglm0	80	1	Besides	besides	IN
cord-306424-gf0bglm0	80	2	the	the	DT
cord-306424-gf0bglm0	80	3	role	role	NN
cord-306424-gf0bglm0	80	4	of	of	IN
cord-306424-gf0bglm0	80	5	RLRs	rlr	NNS
cord-306424-gf0bglm0	80	6	,	,	,
cord-306424-gf0bglm0	80	7	other	other	JJ
cord-306424-gf0bglm0	80	8	RNA	RNA	NNP
cord-306424-gf0bglm0	80	9	sensing	sensing	NN
cord-306424-gf0bglm0	80	10	molecules	molecule	NNS
cord-306424-gf0bglm0	80	11	have	have	VBP
cord-306424-gf0bglm0	80	12	been	be	VBN
cord-306424-gf0bglm0	80	13	shown	show	VBN
cord-306424-gf0bglm0	80	14	to	to	TO
cord-306424-gf0bglm0	80	15	participate	participate	VB
cord-306424-gf0bglm0	80	16	in	in	IN
cord-306424-gf0bglm0	80	17	antiviral	antiviral	JJ
cord-306424-gf0bglm0	80	18	responses	response	NNS
cord-306424-gf0bglm0	80	19	.	.	.
cord-306424-gf0bglm0	81	1	For	for	IN
cord-306424-gf0bglm0	81	2	example	example	NN
cord-306424-gf0bglm0	81	3	,	,	,
cord-306424-gf0bglm0	81	4	of	of	IN
cord-306424-gf0bglm0	81	5	the	the	DT
cord-306424-gf0bglm0	81	6	10	10	CD
cord-306424-gf0bglm0	81	7	types	type	NNS
cord-306424-gf0bglm0	81	8	of	of	IN
cord-306424-gf0bglm0	81	9	TLRs	tlr	NNS
cord-306424-gf0bglm0	81	10	described	describe	VBN
cord-306424-gf0bglm0	81	11	in	in	IN
cord-306424-gf0bglm0	81	12	humans	human	NNS
cord-306424-gf0bglm0	81	13	,	,	,
cord-306424-gf0bglm0	81	14	endosomal	endosomal	NNP
cord-306424-gf0bglm0	81	15	TLRs	TLRs	NNP
cord-306424-gf0bglm0	81	16	3	3	CD
cord-306424-gf0bglm0	81	17	,	,	,
cord-306424-gf0bglm0	81	18	7	7	CD
cord-306424-gf0bglm0	81	19	,	,	,
cord-306424-gf0bglm0	81	20	and	and	CC
cord-306424-gf0bglm0	81	21	8	8	CD
cord-306424-gf0bglm0	81	22	are	be	VBP
cord-306424-gf0bglm0	81	23	known	know	VBN
cord-306424-gf0bglm0	81	24	to	to	TO
cord-306424-gf0bglm0	81	25	have	have	VB
cord-306424-gf0bglm0	81	26	a	a	DT
cord-306424-gf0bglm0	81	27	role	role	NN
cord-306424-gf0bglm0	81	28	in	in	IN
cord-306424-gf0bglm0	81	29	viral	viral	JJ
cord-306424-gf0bglm0	81	30	RNA	RNA	NNP
cord-306424-gf0bglm0	81	31	detection	detection	NN
cord-306424-gf0bglm0	81	32	.	.	.
cord-306424-gf0bglm0	82	1	A	a	DT
cord-306424-gf0bglm0	82	2	detailed	detailed	JJ
cord-306424-gf0bglm0	82	3	overview	overview	NN
cord-306424-gf0bglm0	82	4	on	on	IN
cord-306424-gf0bglm0	82	5	the	the	DT
cord-306424-gf0bglm0	82	6	role	role	NN
cord-306424-gf0bglm0	82	7	of	of	IN
cord-306424-gf0bglm0	82	8	TLRs	TLRs	NNP
cord-306424-gf0bglm0	82	9	in	in	IN
cord-306424-gf0bglm0	82	10	antiviral	antiviral	JJ
cord-306424-gf0bglm0	82	11	signaling	signaling	NN
cord-306424-gf0bglm0	82	12	can	can	MD
cord-306424-gf0bglm0	82	13	be	be	VB
cord-306424-gf0bglm0	82	14	found	find	VBN
cord-306424-gf0bglm0	82	15	elsewhere	elsewhere	RB
cord-306424-gf0bglm0	82	16	[	[	-LRB-
cord-306424-gf0bglm0	82	17	51	51	CD
cord-306424-gf0bglm0	82	18	]	]	-RRB-
cord-306424-gf0bglm0	82	19	.	.	.
cord-306424-gf0bglm0	83	1	Briefly	briefly	RB
cord-306424-gf0bglm0	83	2	,	,	,
cord-306424-gf0bglm0	83	3	TLRs	tlr	NNS
cord-306424-gf0bglm0	83	4	interact	interact	VBP
cord-306424-gf0bglm0	83	5	with	with	IN
cord-306424-gf0bglm0	83	6	various	various	JJ
cord-306424-gf0bglm0	83	7	adaptor	adaptor	NN
cord-306424-gf0bglm0	83	8	molecules	molecule	NNS
cord-306424-gf0bglm0	83	9	after	after	IN
cord-306424-gf0bglm0	83	10	stimulation	stimulation	NN
cord-306424-gf0bglm0	83	11	,	,	,
cord-306424-gf0bglm0	83	12	and	and	CC
cord-306424-gf0bglm0	83	13	the	the	DT
cord-306424-gf0bglm0	83	14	combination	combination	NN
cord-306424-gf0bglm0	83	15	of	of	IN
cord-306424-gf0bglm0	83	16	recruited	recruit	VBN
cord-306424-gf0bglm0	83	17	adaptors	adaptor	NNS
cord-306424-gf0bglm0	83	18	influences	influence	NNS
cord-306424-gf0bglm0	83	19	downstream	downstream	VBP
cord-306424-gf0bglm0	83	20	signaling	signal	VBG
cord-306424-gf0bglm0	83	21	events	event	NNS
cord-306424-gf0bglm0	83	22	.	.	.
cord-306424-gf0bglm0	84	1	TLR3	TLR3	NNP
cord-306424-gf0bglm0	84	2	eventually	eventually	RB
cord-306424-gf0bglm0	84	3	recruits	recruit	VBZ
cord-306424-gf0bglm0	84	4	common	common	JJ
cord-306424-gf0bglm0	84	5	adaptor	adaptor	NN
cord-306424-gf0bglm0	84	6	molecule	molecule	NN
cord-306424-gf0bglm0	84	7	TIR	TIR	NNP
cord-306424-gf0bglm0	84	8	-	-	HYPH
cord-306424-gf0bglm0	84	9	domain	domain	NN
cord-306424-gf0bglm0	84	10	-	-	HYPH
cord-306424-gf0bglm0	84	11	containing	contain	VBG
cord-306424-gf0bglm0	84	12	adapter	adapter	NN
cord-306424-gf0bglm0	84	13	-	-	HYPH
cord-306424-gf0bglm0	84	14	inducing	induce	VBG
cord-306424-gf0bglm0	84	15	interferon	interferon	NN
cord-306424-gf0bglm0	84	16	-	-	HYPH
cord-306424-gf0bglm0	84	17	b	b	LS
cord-306424-gf0bglm0	84	18	(	(	-LRB-
cord-306424-gf0bglm0	84	19	TRIF	TRIF	NNP
cord-306424-gf0bglm0	84	20	)	)	-RRB-
cord-306424-gf0bglm0	84	21	,	,	,
cord-306424-gf0bglm0	84	22	whereas	whereas	IN
cord-306424-gf0bglm0	84	23	TLRs	TLRs	NNP
cord-306424-gf0bglm0	84	24	7	7	CD
cord-306424-gf0bglm0	84	25	and	and	CC
cord-306424-gf0bglm0	84	26	8	8	CD
cord-306424-gf0bglm0	84	27	engage	engage	VB
cord-306424-gf0bglm0	84	28	myeloid	myeloid	JJ
cord-306424-gf0bglm0	84	29	differentiation	differentiation	NN
cord-306424-gf0bglm0	84	30	primary	primary	JJ
cord-306424-gf0bglm0	84	31	response	response	NN
cord-306424-gf0bglm0	84	32	gene	gene	NN
cord-306424-gf0bglm0	84	33	88	88	CD
cord-306424-gf0bglm0	84	34	(	(	-LRB-
cord-306424-gf0bglm0	84	35	MyD88	MyD88	NNS
cord-306424-gf0bglm0	84	36	)	)	-RRB-
cord-306424-gf0bglm0	84	37	.	.	.
cord-306424-gf0bglm0	85	1	As	as	IN
cord-306424-gf0bglm0	85	2	in	in	IN
cord-306424-gf0bglm0	85	3	RLR	RLR	NNP
cord-306424-gf0bglm0	85	4	signaling	signaling	NN
cord-306424-gf0bglm0	85	5	,	,	,
cord-306424-gf0bglm0	85	6	this	this	DT
cord-306424-gf0bglm0	85	7	leads	lead	VBZ
cord-306424-gf0bglm0	85	8	to	to	IN
cord-306424-gf0bglm0	85	9	activation	activation	NN
cord-306424-gf0bglm0	85	10	of	of	IN
cord-306424-gf0bglm0	85	11	kinase	kinase	NN
cord-306424-gf0bglm0	85	12	complexes	complex	NNS
cord-306424-gf0bglm0	86	1	IKKe/	ikke/	CD
cord-306424-gf0bglm0	87	1	TBK1	TBK1	NNP
cord-306424-gf0bglm0	87	2	and	and	CC
cord-306424-gf0bglm0	87	3	IKKa	IKKa	NNPS
cord-306424-gf0bglm0	87	4	/	/	SYM
cord-306424-gf0bglm0	87	5	IKKb	IKKb	NNP
cord-306424-gf0bglm0	87	6	/	/	SYM
cord-306424-gf0bglm0	87	7	IKKg	IKKg	NNS
cord-306424-gf0bglm0	87	8	.	.	.
cord-306424-gf0bglm0	88	1	Furthermore	furthermore	RB
cord-306424-gf0bglm0	88	2	,	,	,
cord-306424-gf0bglm0	88	3	Protein	Protein	NNP
cord-306424-gf0bglm0	88	4	kinase	kinase	NN
cord-306424-gf0bglm0	88	5	R	r	NN
cord-306424-gf0bglm0	88	6	(	(	-LRB-
cord-306424-gf0bglm0	88	7	PKR	PKR	NNP
cord-306424-gf0bglm0	88	8	)	)	-RRB-
cord-306424-gf0bglm0	88	9	and	and	CC
cord-306424-gf0bglm0	88	10	2	2	CD
cord-306424-gf0bglm0	88	11	0	0	CD
cord-306424-gf0bglm0	88	12	,	,	,
cord-306424-gf0bglm0	88	13	5	5	CD
cord-306424-gf0bglm0	88	14	0	0	CD
cord-306424-gf0bglm0	88	15	-oligoadenylate	-oligoadenylate	HYPH
cord-306424-gf0bglm0	88	16	synthetase	synthetase	NN
cord-306424-gf0bglm0	88	17	(	(	-LRB-
cord-306424-gf0bglm0	88	18	OAS	OAS	NNP
cord-306424-gf0bglm0	88	19	)	)	-RRB-
cord-306424-gf0bglm0	88	20	have	have	VBP
cord-306424-gf0bglm0	88	21	been	be	VBN
cord-306424-gf0bglm0	88	22	demonstrated	demonstrate	VBN
cord-306424-gf0bglm0	88	23	to	to	TO
cord-306424-gf0bglm0	88	24	induce	induce	VB
cord-306424-gf0bglm0	88	25	antiviral	antiviral	JJ
cord-306424-gf0bglm0	88	26	activities	activity	NNS
cord-306424-gf0bglm0	88	27	upon	upon	IN
cord-306424-gf0bglm0	88	28	binding	bind	VBG
cord-306424-gf0bglm0	88	29	of	of	IN
cord-306424-gf0bglm0	88	30	dsRNA	dsrna	NN
cord-306424-gf0bglm0	88	31	,	,	,
cord-306424-gf0bglm0	88	32	as	as	IN
cord-306424-gf0bglm0	88	33	is	be	VBZ
cord-306424-gf0bglm0	88	34	described	describe	VBN
cord-306424-gf0bglm0	88	35	in	in	IN
cord-306424-gf0bglm0	88	36	detail	detail	NN
cord-306424-gf0bglm0	88	37	elsewhere	elsewhere	RB
cord-306424-gf0bglm0	88	38	[	[	-LRB-
cord-306424-gf0bglm0	88	39	45	45	CD
cord-306424-gf0bglm0	88	40	]	]	-RRB-
cord-306424-gf0bglm0	88	41	.	.	.
cord-306424-gf0bglm0	89	1	Well	well	RB
cord-306424-gf0bglm0	89	2	-	-	HYPH
cord-306424-gf0bglm0	89	3	established	establish	VBN
cord-306424-gf0bglm0	89	4	examples	example	NNS
cord-306424-gf0bglm0	89	5	of	of	IN
cord-306424-gf0bglm0	89	6	antiviral	antiviral	JJ
cord-306424-gf0bglm0	89	7	activity	activity	NN
cord-306424-gf0bglm0	89	8	provoked	provoke	VBN
cord-306424-gf0bglm0	89	9	by	by	IN
cord-306424-gf0bglm0	89	10	PKR	PKR	NNP
cord-306424-gf0bglm0	89	11	include	include	VBP
cord-306424-gf0bglm0	89	12	inhibition	inhibition	NN
cord-306424-gf0bglm0	89	13	of	of	IN
cord-306424-gf0bglm0	89	14	translation	translation	NN
cord-306424-gf0bglm0	89	15	and	and	CC
cord-306424-gf0bglm0	89	16	inflammasome	inflammasome	NNP
cord-306424-gf0bglm0	89	17	activation	activation	NN
cord-306424-gf0bglm0	89	18	,	,	,
cord-306424-gf0bglm0	89	19	and	and	CC
cord-306424-gf0bglm0	89	20	OAS	OAS	NNP
cord-306424-gf0bglm0	89	21	activates	activate	VBZ
cord-306424-gf0bglm0	89	22	RNase	RNase	NNP
cord-306424-gf0bglm0	89	23	L	L	NNP
cord-306424-gf0bglm0	89	24	to	to	TO
cord-306424-gf0bglm0	89	25	initiate	initiate	VB
cord-306424-gf0bglm0	89	26	degradation	degradation	NN
cord-306424-gf0bglm0	89	27	of	of	IN
cord-306424-gf0bglm0	89	28	host	host	NN
cord-306424-gf0bglm0	89	29	and	and	CC
cord-306424-gf0bglm0	89	30	viral	viral	JJ
cord-306424-gf0bglm0	89	31	RNA	RNA	NNP
cord-306424-gf0bglm0	89	32	.	.	.
cord-306424-gf0bglm0	90	1	In	in	IN
cord-306424-gf0bglm0	90	2	addition	addition	NN
cord-306424-gf0bglm0	90	3	,	,	,
cord-306424-gf0bglm0	90	4	PKR	PKR	NNP
cord-306424-gf0bglm0	90	5	and	and	CC
cord-306424-gf0bglm0	90	6	OAS	OAS	NNP
cord-306424-gf0bglm0	90	7	have	have	VBP
cord-306424-gf0bglm0	90	8	been	be	VBN
cord-306424-gf0bglm0	90	9	suggested	suggest	VBN
cord-306424-gf0bglm0	90	10	to	to	TO
cord-306424-gf0bglm0	90	11	amplify	amplify	VB
cord-306424-gf0bglm0	90	12	RLR	RLR	NNP
cord-306424-gf0bglm0	90	13	-	-	HYPH
cord-306424-gf0bglm0	90	14	mediated	mediate	VBN
cord-306424-gf0bglm0	90	15	antiviral	antiviral	JJ
cord-306424-gf0bglm0	90	16	immune	immune	NN
cord-306424-gf0bglm0	90	17	signaling	signal	VBG
cord-306424-gf0bglm0	90	18	[	[	-LRB-
cord-306424-gf0bglm0	90	19	45	45	CD
cord-306424-gf0bglm0	90	20	]	]	-RRB-
cord-306424-gf0bglm0	90	21	.	.	.
cord-306424-gf0bglm0	91	1	The	the	DT
cord-306424-gf0bglm0	91	2	production	production	NN
cord-306424-gf0bglm0	91	3	and	and	CC
cord-306424-gf0bglm0	91	4	release	release	NN
cord-306424-gf0bglm0	91	5	of	of	IN
cord-306424-gf0bglm0	91	6	IFNs	ifn	NNS
cord-306424-gf0bglm0	91	7	and	and	CC
cord-306424-gf0bglm0	91	8	pro	pro	JJ
cord-306424-gf0bglm0	91	9	-	-	JJ
cord-306424-gf0bglm0	91	10	inflammatory	inflammatory	JJ
cord-306424-gf0bglm0	91	11	cytokines	cytokine	NNS
cord-306424-gf0bglm0	91	12	contributes	contribute	VBZ
cord-306424-gf0bglm0	91	13	to	to	IN
cord-306424-gf0bglm0	91	14	an	an	DT
cord-306424-gf0bglm0	91	15	antiviral	antiviral	JJ
cord-306424-gf0bglm0	91	16	state	state	NN
cord-306424-gf0bglm0	91	17	in	in	IN
cord-306424-gf0bglm0	91	18	both	both	CC
cord-306424-gf0bglm0	91	19	infected	infect	VBN
cord-306424-gf0bglm0	91	20	host	host	NN
cord-306424-gf0bglm0	91	21	cells	cell	NNS
cord-306424-gf0bglm0	91	22	and	and	CC
cord-306424-gf0bglm0	91	23	in	in	IN
cord-306424-gf0bglm0	91	24	(	(	-LRB-
cord-306424-gf0bglm0	91	25	un)infected	un)infecte	VBN
cord-306424-gf0bglm0	91	26	surrounding	surround	VBG
cord-306424-gf0bglm0	91	27	cells	cell	NNS
cord-306424-gf0bglm0	91	28	.	.	.
cord-306424-gf0bglm0	92	1	Despite	despite	IN
cord-306424-gf0bglm0	92	2	the	the	DT
cord-306424-gf0bglm0	92	3	presence	presence	NN
cord-306424-gf0bglm0	92	4	of	of	IN
cord-306424-gf0bglm0	92	5	multiple	multiple	JJ
cord-306424-gf0bglm0	92	6	IFN	IFN	NNP
cord-306424-gf0bglm0	92	7	and	and	CC
cord-306424-gf0bglm0	92	8	receptor	receptor	NN
cord-306424-gf0bglm0	92	9	types	type	NNS
cord-306424-gf0bglm0	92	10	[	[	-LRB-
cord-306424-gf0bglm0	92	11	52	52	CD
cord-306424-gf0bglm0	92	12	]	]	-RRB-
cord-306424-gf0bglm0	92	13	,	,	,
cord-306424-gf0bglm0	92	14	the	the	DT
cord-306424-gf0bglm0	92	15	Janus	Janus	NNP
cord-306424-gf0bglm0	92	16	kinase	kinase	NN
cord-306424-gf0bglm0	92	17	-	-	HYPH
cord-306424-gf0bglm0	92	18	signal	signal	NN
cord-306424-gf0bglm0	92	19	transducer	transducer	NN
cord-306424-gf0bglm0	92	20	and	and	CC
cord-306424-gf0bglm0	92	21	activator	activator	NN
cord-306424-gf0bglm0	92	22	of	of	IN
cord-306424-gf0bglm0	92	23	transcription	transcription	NN
cord-306424-gf0bglm0	92	24	(	(	-LRB-
cord-306424-gf0bglm0	92	25	JAK	JAK	NNP
cord-306424-gf0bglm0	92	26	/	/	SYM
cord-306424-gf0bglm0	92	27	STAT	stat	NN
cord-306424-gf0bglm0	92	28	)	)	-RRB-
cord-306424-gf0bglm0	92	29	pathway	pathway	NN
cord-306424-gf0bglm0	92	30	is	be	VBZ
cord-306424-gf0bglm0	92	31	utilized	utilize	VBN
cord-306424-gf0bglm0	92	32	by	by	IN
cord-306424-gf0bglm0	92	33	all	all	DT
cord-306424-gf0bglm0	92	34	IFNs	ifn	NNS
cord-306424-gf0bglm0	92	35	to	to	TO
cord-306424-gf0bglm0	92	36	establish	establish	VB
cord-306424-gf0bglm0	92	37	expression	expression	NN
cord-306424-gf0bglm0	92	38	of	of	IN
cord-306424-gf0bglm0	92	39	interferon	interferon	NN
cord-306424-gf0bglm0	92	40	-	-	HYPH
cord-306424-gf0bglm0	92	41	stimulated	stimulate	VBN
cord-306424-gf0bglm0	92	42	genes	gene	NNS
cord-306424-gf0bglm0	92	43	(	(	-LRB-
cord-306424-gf0bglm0	92	44	ISGs	ISGs	NNP
cord-306424-gf0bglm0	92	45	)	)	-RRB-
cord-306424-gf0bglm0	92	46	.	.	.
cord-306424-gf0bglm0	93	1	The	the	DT
cord-306424-gf0bglm0	93	2	observation	observation	NN
cord-306424-gf0bglm0	93	3	that	that	IN
cord-306424-gf0bglm0	93	4	a	a	DT
cord-306424-gf0bglm0	93	5	deficiency	deficiency	NN
cord-306424-gf0bglm0	93	6	in	in	IN
cord-306424-gf0bglm0	93	7	separate	separate	JJ
cord-306424-gf0bglm0	93	8	IFN	IFN	NNP
cord-306424-gf0bglm0	93	9	receptors	receptor	NNS
cord-306424-gf0bglm0	93	10	did	do	VBD
cord-306424-gf0bglm0	93	11	not	not	RB
cord-306424-gf0bglm0	93	12	affect	affect	VB
cord-306424-gf0bglm0	93	13	disease	disease	NN
cord-306424-gf0bglm0	93	14	progression	progression	NN
cord-306424-gf0bglm0	93	15	during	during	IN
cord-306424-gf0bglm0	93	16	murine	murine	JJ
cord-306424-gf0bglm0	93	17	SARS	SARS	NNP
cord-306424-gf0bglm0	93	18	-	-	HYPH
cord-306424-gf0bglm0	93	19	CoV	CoV	NNP
cord-306424-gf0bglm0	93	20	infection	infection	NN
cord-306424-gf0bglm0	93	21	,	,	,
cord-306424-gf0bglm0	93	22	in	in	IN
cord-306424-gf0bglm0	93	23	contrast	contrast	NN
cord-306424-gf0bglm0	93	24	to	to	IN
cord-306424-gf0bglm0	93	25	a	a	DT
cord-306424-gf0bglm0	93	26	deficiency	deficiency	NN
cord-306424-gf0bglm0	93	27	in	in	IN
cord-306424-gf0bglm0	93	28	common	common	JJ
cord-306424-gf0bglm0	93	29	signaling	signal	VBG
cord-306424-gf0bglm0	93	30	molecule	molecule	NN
cord-306424-gf0bglm0	93	31	STAT1	stat1	NN
cord-306424-gf0bglm0	93	32	,	,	,
cord-306424-gf0bglm0	93	33	illustrates	illustrate	VBZ
cord-306424-gf0bglm0	93	34	this	this	DT
cord-306424-gf0bglm0	93	35	high	high	JJ
cord-306424-gf0bglm0	93	36	degree	degree	NN
cord-306424-gf0bglm0	93	37	of	of	IN
cord-306424-gf0bglm0	93	38	redundancy	redundancy	NN
cord-306424-gf0bglm0	93	39	[	[	-LRB-
cord-306424-gf0bglm0	93	40	53	53	CD
cord-306424-gf0bglm0	93	41	]	]	-RRB-
cord-306424-gf0bglm0	93	42	.	.	.
cord-306424-gf0bglm0	94	1	At	at	IN
cord-306424-gf0bglm0	94	2	the	the	DT
cord-306424-gf0bglm0	94	3	moment	moment	NN
cord-306424-gf0bglm0	94	4	,	,	,
cord-306424-gf0bglm0	94	5	hundreds	hundred	NNS
cord-306424-gf0bglm0	94	6	of	of	IN
cord-306424-gf0bglm0	94	7	ISGs	isg	NNS
cord-306424-gf0bglm0	94	8	have	have	VBP
cord-306424-gf0bglm0	94	9	been	be	VBN
cord-306424-gf0bglm0	94	10	identified	identify	VBN
cord-306424-gf0bglm0	94	11	.	.	.
cord-306424-gf0bglm0	95	1	However	however	RB
cord-306424-gf0bglm0	95	2	,	,	,
cord-306424-gf0bglm0	95	3	an	an	DT
cord-306424-gf0bglm0	95	4	exact	exact	JJ
cord-306424-gf0bglm0	95	5	function	function	NN
cord-306424-gf0bglm0	95	6	has	have	VBZ
cord-306424-gf0bglm0	95	7	only	only	RB
cord-306424-gf0bglm0	95	8	been	be	VBN
cord-306424-gf0bglm0	95	9	clarified	clarify	VBN
cord-306424-gf0bglm0	95	10	for	for	IN
cord-306424-gf0bglm0	95	11	a	a	DT
cord-306424-gf0bglm0	95	12	relatively	relatively	RB
cord-306424-gf0bglm0	95	13	low	low	JJ
cord-306424-gf0bglm0	95	14	number	number	NN
cord-306424-gf0bglm0	95	15	of	of	IN
cord-306424-gf0bglm0	95	16	the	the	DT
cord-306424-gf0bglm0	95	17	corresponding	correspond	VBG
cord-306424-gf0bglm0	95	18	proteins	protein	NNS
cord-306424-gf0bglm0	95	19	,	,	,
cord-306424-gf0bglm0	95	20	a	a	DT
cord-306424-gf0bglm0	95	21	description	description	NN
cord-306424-gf0bglm0	95	22	of	of	IN
cord-306424-gf0bglm0	95	23	which	which	WDT
cord-306424-gf0bglm0	95	24	can	can	MD
cord-306424-gf0bglm0	95	25	be	be	VB
cord-306424-gf0bglm0	95	26	found	find	VBN
cord-306424-gf0bglm0	95	27	elsewhere	elsewhere	RB
cord-306424-gf0bglm0	95	28	[	[	-LRB-
cord-306424-gf0bglm0	95	29	54	54	CD
cord-306424-gf0bglm0	95	30	]	]	-RRB-
cord-306424-gf0bglm0	95	31	[	[	-LRB-
cord-306424-gf0bglm0	95	32	55	55	CD
cord-306424-gf0bglm0	95	33	]	]	-RRB-
cord-306424-gf0bglm0	95	34	[	[	-LRB-
cord-306424-gf0bglm0	95	35	56	56	CD
cord-306424-gf0bglm0	95	36	]	]	-RRB-
cord-306424-gf0bglm0	95	37	.	.	.
cord-306424-gf0bglm0	96	1	Nonetheless	nonetheless	RB
cord-306424-gf0bglm0	96	2	,	,	,
cord-306424-gf0bglm0	96	3	these	these	DT
cord-306424-gf0bglm0	96	4	studies	study	NNS
cord-306424-gf0bglm0	96	5	suggest	suggest	VBP
cord-306424-gf0bglm0	96	6	that	that	IN
cord-306424-gf0bglm0	96	7	ISGs	ISGs	NNP
cord-306424-gf0bglm0	96	8	exhibit	exhibit	VB
cord-306424-gf0bglm0	96	9	overlapping	overlap	VBG
cord-306424-gf0bglm0	96	10	inhibitory	inhibitory	JJ
cord-306424-gf0bglm0	96	11	activity	activity	NN
cord-306424-gf0bglm0	96	12	towards	towards	IN
cord-306424-gf0bglm0	96	13	most	most	JJS
cord-306424-gf0bglm0	96	14	components	component	NNS
cord-306424-gf0bglm0	96	15	of	of	IN
cord-306424-gf0bglm0	96	16	virus	virus	NN
cord-306424-gf0bglm0	96	17	replication	replication	NN
cord-306424-gf0bglm0	96	18	,	,	,
cord-306424-gf0bglm0	96	19	including	include	VBG
cord-306424-gf0bglm0	96	20	virus	virus	NN
cord-306424-gf0bglm0	96	21	entry	entry	NN
cord-306424-gf0bglm0	96	22	,	,	,
cord-306424-gf0bglm0	96	23	uncoating	uncoating	NN
cord-306424-gf0bglm0	96	24	,	,	,
cord-306424-gf0bglm0	96	25	translation	translation	NN
cord-306424-gf0bglm0	96	26	of	of	IN
cord-306424-gf0bglm0	96	27	viral	viral	JJ
cord-306424-gf0bglm0	96	28	proteins	protein	NNS
cord-306424-gf0bglm0	96	29	,	,	,
cord-306424-gf0bglm0	96	30	RNA	RNA	NNP
cord-306424-gf0bglm0	96	31	replication	replication	NN
cord-306424-gf0bglm0	96	32	,	,	,
cord-306424-gf0bglm0	96	33	and	and	CC
cord-306424-gf0bglm0	96	34	egress	egress	NN
cord-306424-gf0bglm0	96	35	[	[	-LRB-
cord-306424-gf0bglm0	96	36	54	54	CD
cord-306424-gf0bglm0	96	37	]	]	-RRB-
cord-306424-gf0bglm0	96	38	.	.	.
cord-306424-gf0bglm0	97	1	In	in	IN
cord-306424-gf0bglm0	97	2	summary	summary	NN
cord-306424-gf0bglm0	97	3	,	,	,
cord-306424-gf0bglm0	97	4	host	host	NN
cord-306424-gf0bglm0	97	5	cells	cell	NNS
cord-306424-gf0bglm0	97	6	detect	detect	VBP
cord-306424-gf0bglm0	97	7	viral	viral	JJ
cord-306424-gf0bglm0	97	8	RNA	rna	NN
cord-306424-gf0bglm0	97	9	by	by	IN
cord-306424-gf0bglm0	97	10	several	several	JJ
cord-306424-gf0bglm0	97	11	detection	detection	NN
cord-306424-gf0bglm0	97	12	mechanisms	mechanism	NNS
cord-306424-gf0bglm0	97	13	to	to	TO
cord-306424-gf0bglm0	97	14	establish	establish	VB
cord-306424-gf0bglm0	97	15	an	an	DT
cord-306424-gf0bglm0	97	16	antiviral	antiviral	JJ
cord-306424-gf0bglm0	97	17	state	state	NN
cord-306424-gf0bglm0	97	18	via	via	IN
cord-306424-gf0bglm0	97	19	the	the	DT
cord-306424-gf0bglm0	97	20	induction	induction	NN
cord-306424-gf0bglm0	97	21	of	of	IN
cord-306424-gf0bglm0	97	22	IFNs	ifn	NNS
cord-306424-gf0bglm0	97	23	and	and	CC
cord-306424-gf0bglm0	97	24	pro	pro	JJ
cord-306424-gf0bglm0	97	25	-	-	JJ
cord-306424-gf0bglm0	97	26	inflammatory	inflammatory	JJ
cord-306424-gf0bglm0	97	27	cytokines	cytokine	NNS
cord-306424-gf0bglm0	97	28	,	,	,
cord-306424-gf0bglm0	97	29	leading	lead	VBG
cord-306424-gf0bglm0	97	30	to	to	IN
cord-306424-gf0bglm0	97	31	expression	expression	NN
cord-306424-gf0bglm0	97	32	of	of	IN
cord-306424-gf0bglm0	97	33	ISGs	isg	NNS
cord-306424-gf0bglm0	97	34	.	.	.
cord-306424-gf0bglm0	98	1	As	as	IN
cord-306424-gf0bglm0	98	2	mentioned	mention	VBN
cord-306424-gf0bglm0	98	3	earlier	early	RBR
cord-306424-gf0bglm0	98	4	,	,	,
cord-306424-gf0bglm0	98	5	MAVS	MAVS	NNP
cord-306424-gf0bglm0	98	6	localized	localize	VBN
cord-306424-gf0bglm0	98	7	on	on	IN
cord-306424-gf0bglm0	98	8	mitochondria	mitochondrion	NNS
cord-306424-gf0bglm0	98	9	is	be	VBZ
cord-306424-gf0bglm0	98	10	a	a	DT
cord-306424-gf0bglm0	98	11	key	key	JJ
cord-306424-gf0bglm0	98	12	player	player	NN
cord-306424-gf0bglm0	98	13	in	in	IN
cord-306424-gf0bglm0	98	14	antiviral	antiviral	JJ
cord-306424-gf0bglm0	98	15	signaling	signaling	NN
cord-306424-gf0bglm0	98	16	.	.	.
cord-306424-gf0bglm0	99	1	Therefore	therefore	RB
cord-306424-gf0bglm0	99	2	,	,	,
cord-306424-gf0bglm0	99	3	studies	study	NNS
cord-306424-gf0bglm0	99	4	demonstrating	demonstrate	VBG
cord-306424-gf0bglm0	99	5	that	that	IN
cord-306424-gf0bglm0	99	6	the	the	DT
cord-306424-gf0bglm0	99	7	MAVS	MAVS	NNP
cord-306424-gf0bglm0	99	8	adaptor	adaptor	NN
cord-306424-gf0bglm0	99	9	molecule	molecule	NN
cord-306424-gf0bglm0	99	10	STING	sting	NN
cord-306424-gf0bglm0	99	11	is	be	VBZ
cord-306424-gf0bglm0	99	12	located	locate	VBN
cord-306424-gf0bglm0	99	13	on	on	IN
cord-306424-gf0bglm0	99	14	the	the	DT
cord-306424-gf0bglm0	99	15	ER	ER	NNP
cord-306424-gf0bglm0	99	16	implied	imply	VBD
cord-306424-gf0bglm0	99	17	that	that	IN
cord-306424-gf0bglm0	99	18	earlier	early	RBR
cord-306424-gf0bglm0	99	19	identified	identify	VBN
cord-306424-gf0bglm0	99	20	contacts	contact	NNS
cord-306424-gf0bglm0	99	21	between	between	IN
cord-306424-gf0bglm0	99	22	mitochondrial	mitochondrial	JJ
cord-306424-gf0bglm0	99	23	membranes	membrane	NNS
cord-306424-gf0bglm0	99	24	and	and	CC
cord-306424-gf0bglm0	99	25	ER	ER	NNP
cord-306424-gf0bglm0	99	26	membranes	membrane	NNS
cord-306424-gf0bglm0	99	27	(	(	-LRB-
cord-306424-gf0bglm0	99	28	mitochondrion	mitochondrion	NN
cord-306424-gf0bglm0	99	29	-	-	HYPH
cord-306424-gf0bglm0	99	30	associated	associate	VBN
cord-306424-gf0bglm0	99	31	membranes	membrane	NNS
cord-306424-gf0bglm0	99	32	:	:	:
cord-306424-gf0bglm0	99	33	MAMs	mam	NNS
cord-306424-gf0bglm0	99	34	)	)	-RRB-
cord-306424-gf0bglm0	99	35	were	be	VBD
cord-306424-gf0bglm0	99	36	possibly	possibly	RB
cord-306424-gf0bglm0	99	37	involved	involved	JJ
cord-306424-gf0bglm0	99	38	in	in	IN
cord-306424-gf0bglm0	99	39	antiviral	antiviral	JJ
cord-306424-gf0bglm0	99	40	signaling	signal	VBG
cord-306424-gf0bglm0	99	41	[	[	-LRB-
cord-306424-gf0bglm0	99	42	57	57	CD
cord-306424-gf0bglm0	99	43	]	]	-RRB-
cord-306424-gf0bglm0	99	44	.	.	.
cord-306424-gf0bglm0	100	1	In	in	IN
cord-306424-gf0bglm0	100	2	support	support	NN
cord-306424-gf0bglm0	100	3	of	of	IN
cord-306424-gf0bglm0	100	4	this	this	DT
cord-306424-gf0bglm0	100	5	theory	theory	NN
cord-306424-gf0bglm0	100	6	,	,	,
cord-306424-gf0bglm0	100	7	expression	expression	NN
cord-306424-gf0bglm0	100	8	of	of	IN
cord-306424-gf0bglm0	100	9	a	a	DT
cord-306424-gf0bglm0	100	10	MAM	mam	NN
cord-306424-gf0bglm0	100	11	-	-	HYPH
cord-306424-gf0bglm0	100	12	enriched	enrich	VBN
cord-306424-gf0bglm0	100	13	marker	marker	NN
cord-306424-gf0bglm0	100	14	protein	protein	NN
cord-306424-gf0bglm0	100	15	followed	follow	VBN
cord-306424-gf0bglm0	100	16	by	by	IN
cord-306424-gf0bglm0	100	17	cell	cell	NN
cord-306424-gf0bglm0	100	18	fractionation	fractionation	NN
cord-306424-gf0bglm0	100	19	revealed	reveal	VBD
cord-306424-gf0bglm0	100	20	that	that	IN
cord-306424-gf0bglm0	100	21	MAVS	MAVS	NNP
cord-306424-gf0bglm0	100	22	localizes	localize	VBZ
cord-306424-gf0bglm0	100	23	to	to	IN
cord-306424-gf0bglm0	100	24	MAMs	mam	NNS
cord-306424-gf0bglm0	100	25	,	,	,
cord-306424-gf0bglm0	100	26	which	which	WDT
cord-306424-gf0bglm0	100	27	was	be	VBD
cord-306424-gf0bglm0	100	28	supported	support	VBN
cord-306424-gf0bglm0	100	29	by	by	IN
cord-306424-gf0bglm0	100	30	immunofluorescence	immunofluorescence	NN
cord-306424-gf0bglm0	100	31	assays	assay	NNS
cord-306424-gf0bglm0	100	32	of	of	IN
cord-306424-gf0bglm0	100	33	MAVS	MAVS	NNPS
cord-306424-gf0bglm0	100	34	and	and	CC
cord-306424-gf0bglm0	100	35	MAMenriched	mamenriched	JJ
cord-306424-gf0bglm0	100	36	proteins	protein	NNS
cord-306424-gf0bglm0	100	37	[	[	-LRB-
cord-306424-gf0bglm0	100	38	58	58	CD
cord-306424-gf0bglm0	100	39	]	]	-RRB-
cord-306424-gf0bglm0	100	40	.	.	.
cord-306424-gf0bglm0	101	1	Additionally	additionally	RB
cord-306424-gf0bglm0	101	2	,	,	,
cord-306424-gf0bglm0	101	3	immunoprecipitation	immunoprecipitation	NN
cord-306424-gf0bglm0	101	4	analysis	analysis	NN
cord-306424-gf0bglm0	101	5	of	of	IN
cord-306424-gf0bglm0	101	6	the	the	DT
cord-306424-gf0bglm0	101	7	MAM	MAM	NNP
cord-306424-gf0bglm0	101	8	fraction	fraction	NN
cord-306424-gf0bglm0	101	9	of	of	IN
cord-306424-gf0bglm0	101	10	Sendai	Sendai	NNP
cord-306424-gf0bglm0	101	11	virus	virus	NN
cord-306424-gf0bglm0	101	12	-	-	HYPH
cord-306424-gf0bglm0	101	13	infected	infect	VBN
cord-306424-gf0bglm0	101	14	hepatocytes	hepatocyte	NNS
cord-306424-gf0bglm0	101	15	confirmed	confirm	VBD
cord-306424-gf0bglm0	101	16	that	that	IN
cord-306424-gf0bglm0	101	17	MAM	mam	NN
cord-306424-gf0bglm0	101	18	-	-	HYPH
cord-306424-gf0bglm0	101	19	localized	localize	VBN
cord-306424-gf0bglm0	101	20	MAVS	MAVS	NNP
cord-306424-gf0bglm0	101	21	interacts	interact	VBZ
cord-306424-gf0bglm0	101	22	with	with	IN
cord-306424-gf0bglm0	101	23	RIG	rig	NN
cord-306424-gf0bglm0	101	24	-	-	:
cord-306424-gf0bglm0	101	25	I	i	NN
cord-306424-gf0bglm0	101	26	and	and	CC
cord-306424-gf0bglm0	101	27	signaling	signal	VBG
cord-306424-gf0bglm0	101	28	cofactor	cofactor	NN
cord-306424-gf0bglm0	102	1	TRAF3	TRAF3	NNP
cord-306424-gf0bglm0	102	2	[	[	-LRB-
cord-306424-gf0bglm0	102	3	58	58	CD
cord-306424-gf0bglm0	102	4	]	]	-RRB-
cord-306424-gf0bglm0	102	5	,	,	.
cord-306424-gf0bglm0	103	1	indicating	indicate	VBG
cord-306424-gf0bglm0	103	2	that	that	IN
cord-306424-gf0bglm0	103	3	MAMs	mam	NNS
cord-306424-gf0bglm0	103	4	are	be	VBP
cord-306424-gf0bglm0	103	5	involved	involve	VBN
cord-306424-gf0bglm0	103	6	in	in	IN
cord-306424-gf0bglm0	103	7	the	the	DT
cord-306424-gf0bglm0	103	8	RLR	RLR	NNP
cord-306424-gf0bglm0	103	9	-	-	HYPH
cord-306424-gf0bglm0	103	10	mediated	mediate	VBN
cord-306424-gf0bglm0	103	11	antiviral	antiviral	JJ
cord-306424-gf0bglm0	103	12	immune	immune	NN
cord-306424-gf0bglm0	103	13	signaling	signal	VBG
cord-306424-gf0bglm0	103	14	pathway	pathway	NN
cord-306424-gf0bglm0	103	15	.	.	.
cord-306424-gf0bglm0	104	1	Therefore	therefore	RB
cord-306424-gf0bglm0	104	2	,	,	,
cord-306424-gf0bglm0	104	3	MAMs	mam	NNS
cord-306424-gf0bglm0	104	4	function	function	VBP
cord-306424-gf0bglm0	104	5	as	as	IN
cord-306424-gf0bglm0	104	6	important	important	JJ
cord-306424-gf0bglm0	104	7	signaling	signal	VBG
cord-306424-gf0bglm0	104	8	platforms	platform	NNS
cord-306424-gf0bglm0	104	9	that	that	WDT
cord-306424-gf0bglm0	104	10	govern	govern	VBP
cord-306424-gf0bglm0	104	11	expression	expression	NN
cord-306424-gf0bglm0	104	12	of	of	IN
cord-306424-gf0bglm0	104	13	type	type	NN
cord-306424-gf0bglm0	104	14	I	-PRON-	PRP
cord-306424-gf0bglm0	104	15	and	and	CC
cord-306424-gf0bglm0	104	16	III	III	NNP
cord-306424-gf0bglm0	104	17	IFNs	ifn	NNS
cord-306424-gf0bglm0	104	18	.	.	.
cord-306424-gf0bglm0	105	1	Interestingly	interestingly	RB
cord-306424-gf0bglm0	105	2	,	,	,
cord-306424-gf0bglm0	105	3	MAVS	MAVS	NNP
cord-306424-gf0bglm0	105	4	is	be	VBZ
cord-306424-gf0bglm0	105	5	also	also	RB
cord-306424-gf0bglm0	105	6	expressed	express	VBN
cord-306424-gf0bglm0	105	7	on	on	IN
cord-306424-gf0bglm0	105	8	peroxisomal	peroxisomal	JJ
cord-306424-gf0bglm0	105	9	membranes	membrane	NNS
cord-306424-gf0bglm0	105	10	,	,	,
cord-306424-gf0bglm0	105	11	and	and	CC
cord-306424-gf0bglm0	105	12	interacts	interact	VBZ
cord-306424-gf0bglm0	105	13	with	with	IN
cord-306424-gf0bglm0	105	14	stimulated	stimulated	JJ
cord-306424-gf0bglm0	105	15	RLRs	rlr	NNS
cord-306424-gf0bglm0	105	16	during	during	IN
cord-306424-gf0bglm0	105	17	viral	viral	JJ
cord-306424-gf0bglm0	105	18	infection	infection	NN
cord-306424-gf0bglm0	105	19	[	[	-LRB-
cord-306424-gf0bglm0	105	20	59	59	CD
cord-306424-gf0bglm0	105	21	]	]	-RRB-
cord-306424-gf0bglm0	105	22	.	.	.
cord-306424-gf0bglm0	106	1	However	however	RB
cord-306424-gf0bglm0	106	2	,	,	,
cord-306424-gf0bglm0	106	3	in	in	IN
cord-306424-gf0bglm0	106	4	contrast	contrast	NN
cord-306424-gf0bglm0	106	5	to	to	IN
cord-306424-gf0bglm0	106	6	its	-PRON-	PRP$
cord-306424-gf0bglm0	106	7	mitochondrial	mitochondrial	JJ
cord-306424-gf0bglm0	106	8	counterpart	counterpart	NN
cord-306424-gf0bglm0	106	9	,	,	,
cord-306424-gf0bglm0	106	10	peroxisomal	peroxisomal	JJ
cord-306424-gf0bglm0	106	11	MAVS	MAVS	NNPS
cord-306424-gf0bglm0	106	12	was	be	VBD
cord-306424-gf0bglm0	106	13	found	find	VBN
cord-306424-gf0bglm0	106	14	to	to	TO
cord-306424-gf0bglm0	106	15	induce	induce	VB
cord-306424-gf0bglm0	106	16	expression	expression	NN
cord-306424-gf0bglm0	106	17	of	of	IN
cord-306424-gf0bglm0	106	18	ISGs	isg	NNS
cord-306424-gf0bglm0	106	19	by	by	IN
cord-306424-gf0bglm0	106	20	an	an	DT
cord-306424-gf0bglm0	106	21	IFN	IFN	NNP
cord-306424-gf0bglm0	106	22	-	-	HYPH
cord-306424-gf0bglm0	106	23	independent	independent	JJ
cord-306424-gf0bglm0	106	24	mechanism	mechanism	NN
cord-306424-gf0bglm0	106	25	,	,	,
cord-306424-gf0bglm0	106	26	and	and	CC
cord-306424-gf0bglm0	106	27	this	this	DT
cord-306424-gf0bglm0	106	28	relatively	relatively	RB
cord-306424-gf0bglm0	106	29	rapid	rapid	JJ
cord-306424-gf0bglm0	106	30	process	process	NN
cord-306424-gf0bglm0	106	31	seems	seem	VBZ
cord-306424-gf0bglm0	106	32	to	to	TO
cord-306424-gf0bglm0	106	33	provide	provide	VB
cord-306424-gf0bglm0	106	34	short	short	JJ
cord-306424-gf0bglm0	106	35	-	-	HYPH
cord-306424-gf0bglm0	106	36	term	term	NN
cord-306424-gf0bglm0	106	37	protection	protection	NN
cord-306424-gf0bglm0	106	38	until	until	IN
cord-306424-gf0bglm0	106	39	the	the	DT
cord-306424-gf0bglm0	106	40	IFN	IFN	NNP
cord-306424-gf0bglm0	106	41	-	-	HYPH
cord-306424-gf0bglm0	106	42	dependent	dependent	JJ
cord-306424-gf0bglm0	106	43	expression	expression	NN
cord-306424-gf0bglm0	106	44	of	of	IN
cord-306424-gf0bglm0	106	45	ISGs	isg	NNS
cord-306424-gf0bglm0	106	46	mediated	mediate	VBN
cord-306424-gf0bglm0	106	47	by	by	IN
cord-306424-gf0bglm0	106	48	other	other	JJ
cord-306424-gf0bglm0	106	49	viral	viral	JJ
cord-306424-gf0bglm0	106	50	RNA	rna	NN
cord-306424-gf0bglm0	106	51	-	-	HYPH
cord-306424-gf0bglm0	106	52	sensing	sensing	NN
cord-306424-gf0bglm0	106	53	mechanisms	mechanism	NNS
cord-306424-gf0bglm0	106	54	is	be	VBZ
cord-306424-gf0bglm0	106	55	established	establish	VBN
cord-306424-gf0bglm0	106	56	[	[	-LRB-
cord-306424-gf0bglm0	106	57	59	59	CD
cord-306424-gf0bglm0	106	58	]	]	-RRB-
cord-306424-gf0bglm0	106	59	.	.	.
cord-306424-gf0bglm0	107	1	Interestingly	interestingly	RB
cord-306424-gf0bglm0	107	2	,	,	,
cord-306424-gf0bglm0	107	3	recent	recent	JJ
cord-306424-gf0bglm0	107	4	studies	study	NNS
cord-306424-gf0bglm0	107	5	found	find	VBD
cord-306424-gf0bglm0	107	6	that	that	IN
cord-306424-gf0bglm0	107	7	direct	direct	JJ
cord-306424-gf0bglm0	107	8	contacts	contact	NNS
cord-306424-gf0bglm0	107	9	between	between	IN
cord-306424-gf0bglm0	107	10	peroxisomes	peroxisome	NNS
cord-306424-gf0bglm0	107	11	and	and	CC
cord-306424-gf0bglm0	107	12	ER	ER	NNP
cord-306424-gf0bglm0	107	13	membranes	membrane	NNS
cord-306424-gf0bglm0	107	14	were	be	VBD
cord-306424-gf0bglm0	107	15	involved	involve	VBN
cord-306424-gf0bglm0	107	16	in	in	IN
cord-306424-gf0bglm0	107	17	maintaining	maintain	VBG
cord-306424-gf0bglm0	107	18	peroxisomal	peroxisomal	JJ
cord-306424-gf0bglm0	107	19	function	function	NN
cord-306424-gf0bglm0	107	20	[	[	-LRB-
cord-306424-gf0bglm0	107	21	60	60	CD
cord-306424-gf0bglm0	107	22	]	]	-RRB-
cord-306424-gf0bglm0	107	23	[	[	-LRB-
cord-306424-gf0bglm0	107	24	61	61	CD
cord-306424-gf0bglm0	107	25	]	]	-RRB-
cord-306424-gf0bglm0	107	26	[	[	-LRB-
cord-306424-gf0bglm0	107	27	62	62	CD
cord-306424-gf0bglm0	107	28	]	]	-RRB-
cord-306424-gf0bglm0	107	29	,	,	,
cord-306424-gf0bglm0	107	30	raising	raise	VBG
cord-306424-gf0bglm0	107	31	the	the	DT
cord-306424-gf0bglm0	107	32	question	question	NN
cord-306424-gf0bglm0	107	33	whether	whether	IN
cord-306424-gf0bglm0	107	34	these	these	DT
cord-306424-gf0bglm0	107	35	contact	contact	NN
cord-306424-gf0bglm0	107	36	sites	site	NNS
cord-306424-gf0bglm0	107	37	might	may	MD
cord-306424-gf0bglm0	107	38	also	also	RB
cord-306424-gf0bglm0	107	39	regulate	regulate	VB
cord-306424-gf0bglm0	107	40	antiviral	antiviral	JJ
cord-306424-gf0bglm0	107	41	immunity	immunity	NN
cord-306424-gf0bglm0	107	42	-	-	HYPH
cord-306424-gf0bglm0	107	43	related	relate	VBN
cord-306424-gf0bglm0	107	44	processes	process	NNS
cord-306424-gf0bglm0	107	45	.	.	.
cord-306424-gf0bglm0	108	1	In	in	IN
cord-306424-gf0bglm0	108	2	summary	summary	NN
cord-306424-gf0bglm0	108	3	,	,	,
cord-306424-gf0bglm0	108	4	peroxisomal	peroxisomal	JJ
cord-306424-gf0bglm0	108	5	and	and	CC
cord-306424-gf0bglm0	108	6	mitochondrial	mitochondrial	JJ
cord-306424-gf0bglm0	108	7	membranes	membrane	NNS
cord-306424-gf0bglm0	108	8	and	and	CC
cord-306424-gf0bglm0	108	9	their	-PRON-	PRP$
cord-306424-gf0bglm0	108	10	contactsites	contactsite	NNS
cord-306424-gf0bglm0	108	11	with	with	IN
cord-306424-gf0bglm0	108	12	the	the	DT
cord-306424-gf0bglm0	108	13	ER	ER	NNP
cord-306424-gf0bglm0	108	14	are	be	VBP
cord-306424-gf0bglm0	108	15	important	important	JJ
cord-306424-gf0bglm0	108	16	regions	region	NNS
cord-306424-gf0bglm0	108	17	for	for	IN
cord-306424-gf0bglm0	108	18	converting	convert	VBG
cord-306424-gf0bglm0	108	19	viral	viral	JJ
cord-306424-gf0bglm0	108	20	RNA	RNA	NNP
cord-306424-gf0bglm0	108	21	detection	detection	NN
cord-306424-gf0bglm0	108	22	by	by	IN
cord-306424-gf0bglm0	108	23	RLRs	rlr	NNS
cord-306424-gf0bglm0	108	24	to	to	IN
cord-306424-gf0bglm0	108	25	downstream	downstream	JJ
cord-306424-gf0bglm0	108	26	events	event	NNS
cord-306424-gf0bglm0	108	27	required	require	VBN
cord-306424-gf0bglm0	108	28	for	for	IN
cord-306424-gf0bglm0	108	29	establishing	establish	VBG
cord-306424-gf0bglm0	108	30	an	an	DT
cord-306424-gf0bglm0	108	31	antiviral	antiviral	JJ
cord-306424-gf0bglm0	108	32	state	state	NN
cord-306424-gf0bglm0	108	33	.	.	.
cord-306424-gf0bglm0	109	1	Besides	besides	IN
cord-306424-gf0bglm0	109	2	MAMs	mam	NNS
cord-306424-gf0bglm0	109	3	,	,	,
cord-306424-gf0bglm0	109	4	increasing	increase	VBG
cord-306424-gf0bglm0	109	5	evidence	evidence	NN
cord-306424-gf0bglm0	109	6	suggest	suggest	VBP
cord-306424-gf0bglm0	109	7	a	a	DT
cord-306424-gf0bglm0	109	8	role	role	NN
cord-306424-gf0bglm0	109	9	for	for	IN
cord-306424-gf0bglm0	109	10	stress	stress	NN
cord-306424-gf0bglm0	109	11	granules	granule	NNS
cord-306424-gf0bglm0	109	12	(	(	-LRB-
cord-306424-gf0bglm0	109	13	SGs	SGs	NNP
cord-306424-gf0bglm0	109	14	)	)	-RRB-
cord-306424-gf0bglm0	109	15	in	in	IN
cord-306424-gf0bglm0	109	16	antiviral	antiviral	JJ
cord-306424-gf0bglm0	109	17	immune	immune	NN
cord-306424-gf0bglm0	109	18	signaling	signaling	NN
cord-306424-gf0bglm0	109	19	.	.	.
cord-306424-gf0bglm0	110	1	SGs	SGs	NNP
cord-306424-gf0bglm0	110	2	are	be	VBP
cord-306424-gf0bglm0	110	3	nonmembranous	nonmembranous	JJ
cord-306424-gf0bglm0	110	4	compartments	compartment	NNS
cord-306424-gf0bglm0	110	5	in	in	IN
cord-306424-gf0bglm0	110	6	the	the	DT
cord-306424-gf0bglm0	110	7	cell	cell	NN
cord-306424-gf0bglm0	110	8	that	that	WDT
cord-306424-gf0bglm0	110	9	contain	contain	VBP
cord-306424-gf0bglm0	110	10	aggregates	aggregate	NNS
cord-306424-gf0bglm0	110	11	of	of	IN
cord-306424-gf0bglm0	110	12	ribonucleoprotein	ribonucleoprotein	NN
cord-306424-gf0bglm0	110	13	(	(	-LRB-
cord-306424-gf0bglm0	110	14	RNP	RNP	NNP
cord-306424-gf0bglm0	110	15	)	)	-RRB-
cord-306424-gf0bglm0	110	16	and	and	CC
cord-306424-gf0bglm0	110	17	mRNA	mrna	NN
cord-306424-gf0bglm0	110	18	,	,	,
cord-306424-gf0bglm0	110	19	and	and	CC
cord-306424-gf0bglm0	110	20	are	be	VBP
cord-306424-gf0bglm0	110	21	formed	form	VBN
cord-306424-gf0bglm0	110	22	as	as	IN
cord-306424-gf0bglm0	110	23	a	a	DT
cord-306424-gf0bglm0	110	24	physiological	physiological	JJ
cord-306424-gf0bglm0	110	25	response	response	NN
cord-306424-gf0bglm0	110	26	to	to	IN
cord-306424-gf0bglm0	110	27	various	various	JJ
cord-306424-gf0bglm0	110	28	stress	stress	NN
cord-306424-gf0bglm0	110	29	stimuli	stimulus	NNS
cord-306424-gf0bglm0	110	30	that	that	WDT
cord-306424-gf0bglm0	110	31	cause	cause	VBP
cord-306424-gf0bglm0	110	32	temporal	temporal	JJ
cord-306424-gf0bglm0	110	33	stalling	stalling	NN
cord-306424-gf0bglm0	110	34	of	of	IN
cord-306424-gf0bglm0	110	35	mRNA	mRNA	NNP
cord-306424-gf0bglm0	110	36	translation	translation	NN
cord-306424-gf0bglm0	110	37	,	,	,
cord-306424-gf0bglm0	110	38	suggestively	suggestively	RB
cord-306424-gf0bglm0	110	39	preventing	prevent	VBG
cord-306424-gf0bglm0	110	40	accumulation	accumulation	NN
cord-306424-gf0bglm0	110	41	[	[	-LRB-
cord-306424-gf0bglm0	110	42	63	63	CD
cord-306424-gf0bglm0	110	43	]	]	-RRB-
cord-306424-gf0bglm0	110	44	.	.	.
cord-306424-gf0bglm0	111	1	Consistent	consistent	JJ
cord-306424-gf0bglm0	111	2	with	with	IN
cord-306424-gf0bglm0	111	3	the	the	DT
cord-306424-gf0bglm0	111	4	function	function	NN
cord-306424-gf0bglm0	111	5	of	of	IN
cord-306424-gf0bglm0	111	6	this	this	DT
cord-306424-gf0bglm0	111	7	structure	structure	NN
cord-306424-gf0bglm0	111	8	,	,	,
cord-306424-gf0bglm0	111	9	inhibition	inhibition	NN
cord-306424-gf0bglm0	111	10	of	of	IN
cord-306424-gf0bglm0	111	11	translation	translation	NN
cord-306424-gf0bglm0	111	12	through	through	IN
cord-306424-gf0bglm0	111	13	the	the	DT
cord-306424-gf0bglm0	111	14	inactivation	inactivation	NN
cord-306424-gf0bglm0	111	15	of	of	IN
cord-306424-gf0bglm0	111	16	eukaryotic	eukaryotic	JJ
cord-306424-gf0bglm0	111	17	translation	translation	NN
cord-306424-gf0bglm0	111	18	initiation	initiation	NN
cord-306424-gf0bglm0	111	19	factor	factor	NN
cord-306424-gf0bglm0	111	20	(	(	-LRB-
cord-306424-gf0bglm0	111	21	eIF)2a	eIF)2a	NNP
cord-306424-gf0bglm0	111	22	by	by	IN
cord-306424-gf0bglm0	111	23	phosphorylation	phosphorylation	NN
cord-306424-gf0bglm0	111	24	is	be	VBZ
cord-306424-gf0bglm0	111	25	an	an	DT
cord-306424-gf0bglm0	111	26	important	important	JJ
cord-306424-gf0bglm0	111	27	cue	cue	NN
cord-306424-gf0bglm0	111	28	for	for	IN
cord-306424-gf0bglm0	111	29	SG	SG	NNP
cord-306424-gf0bglm0	111	30	formation	formation	NN
cord-306424-gf0bglm0	111	31	[	[	-LRB-
cord-306424-gf0bglm0	111	32	63	63	CD
cord-306424-gf0bglm0	111	33	]	]	-RRB-
cord-306424-gf0bglm0	111	34	.	.	.
cord-306424-gf0bglm0	112	1	Considering	consider	VBG
cord-306424-gf0bglm0	112	2	that	that	IN
cord-306424-gf0bglm0	112	3	various	various	JJ
cord-306424-gf0bglm0	112	4	RNA	RNA	NNP
cord-306424-gf0bglm0	112	5	virus	virus	NN
cord-306424-gf0bglm0	112	6	infections	infection	NNS
cord-306424-gf0bglm0	112	7	result	result	VBP
cord-306424-gf0bglm0	112	8	in	in	IN
cord-306424-gf0bglm0	112	9	shutdown	shutdown	NN
cord-306424-gf0bglm0	112	10	of	of	IN
cord-306424-gf0bglm0	112	11	host	host	NN
cord-306424-gf0bglm0	112	12	translation	translation	NN
cord-306424-gf0bglm0	112	13	by	by	IN
cord-306424-gf0bglm0	112	14	inactivation	inactivation	NN
cord-306424-gf0bglm0	112	15	of	of	IN
cord-306424-gf0bglm0	112	16	eIF2a	eIF2a	NNP
cord-306424-gf0bglm0	112	17	by	by	IN
cord-306424-gf0bglm0	112	18	for	for	IN
cord-306424-gf0bglm0	112	19	example	example	NN
cord-306424-gf0bglm0	112	20	PKR	PKR	NNP
cord-306424-gf0bglm0	112	21	,	,	,
cord-306424-gf0bglm0	112	22	it	-PRON-	PRP
cord-306424-gf0bglm0	112	23	is	be	VBZ
cord-306424-gf0bglm0	112	24	now	now	RB
cord-306424-gf0bglm0	112	25	known	know	VBN
cord-306424-gf0bglm0	112	26	that	that	DT
cord-306424-gf0bglm0	112	27	formation	formation	NN
cord-306424-gf0bglm0	112	28	of	of	IN
cord-306424-gf0bglm0	112	29	SGs	SGs	NNP
cord-306424-gf0bglm0	112	30	occurs	occur	VBZ
cord-306424-gf0bglm0	112	31	to	to	IN
cord-306424-gf0bglm0	112	32	different	different	JJ
cord-306424-gf0bglm0	112	33	extends	extend	NNS
cord-306424-gf0bglm0	112	34	during	during	IN
cord-306424-gf0bglm0	112	35	infection	infection	NN
cord-306424-gf0bglm0	112	36	with	with	IN
cord-306424-gf0bglm0	112	37	various	various	JJ
cord-306424-gf0bglm0	112	38	RNA	RNA	NNP
cord-306424-gf0bglm0	112	39	viruses	virus	NNS
cord-306424-gf0bglm0	112	40	,	,	,
cord-306424-gf0bglm0	112	41	including	include	VBG
cord-306424-gf0bglm0	112	42	HCV	HCV	NNP
cord-306424-gf0bglm0	112	43	,	,	,
cord-306424-gf0bglm0	112	44	DENV	DENV	NNP
cord-306424-gf0bglm0	112	45	,	,	,
cord-306424-gf0bglm0	112	46	and	and	CC
cord-306424-gf0bglm0	112	47	SFV	SFV	NNP
cord-306424-gf0bglm0	112	48	[	[	-LRB-
cord-306424-gf0bglm0	112	49	63	63	CD
cord-306424-gf0bglm0	112	50	,	,	,
cord-306424-gf0bglm0	112	51	64	64	CD
cord-306424-gf0bglm0	112	52	]	]	-RRB-
cord-306424-gf0bglm0	112	53	.	.	.
cord-306424-gf0bglm0	113	1	Interestingly	interestingly	RB
cord-306424-gf0bglm0	113	2	,	,	,
cord-306424-gf0bglm0	113	3	multiple	multiple	JJ
cord-306424-gf0bglm0	113	4	lines	line	NNS
cord-306424-gf0bglm0	113	5	of	of	IN
cord-306424-gf0bglm0	113	6	evidence	evidence	NN
cord-306424-gf0bglm0	113	7	have	have	VBP
cord-306424-gf0bglm0	113	8	demonstrated	demonstrate	VBN
cord-306424-gf0bglm0	113	9	that	that	IN
cord-306424-gf0bglm0	113	10	SGs	SGs	NNP
cord-306424-gf0bglm0	113	11	in	in	IN
cord-306424-gf0bglm0	113	12	encephalomyocarditis	encephalomyocarditis	NNP
cord-306424-gf0bglm0	113	13	virus	virus	NN
cord-306424-gf0bglm0	113	14	-	-	:
cord-306424-gf0bglm0	113	15	or	or	CC
cord-306424-gf0bglm0	113	16	influenza	influenza	NN
cord-306424-gf0bglm0	113	17	virus	virus	NN
cord-306424-gf0bglm0	113	18	-	-	HYPH
cord-306424-gf0bglm0	113	19	infected	infect	VBN
cord-306424-gf0bglm0	113	20	cells	cell	NNS
cord-306424-gf0bglm0	113	21	contain	contain	VBP
cord-306424-gf0bglm0	113	22	multiple	multiple	JJ
cord-306424-gf0bglm0	113	23	RNA	RNA	NNP
cord-306424-gf0bglm0	113	24	sensing	sensing	NN
cord-306424-gf0bglm0	113	25	molecules	molecule	NNS
cord-306424-gf0bglm0	113	26	that	that	WDT
cord-306424-gf0bglm0	113	27	were	be	VBD
cord-306424-gf0bglm0	113	28	found	find	VBN
cord-306424-gf0bglm0	113	29	to	to	TO
cord-306424-gf0bglm0	113	30	contribute	contribute	VB
cord-306424-gf0bglm0	113	31	to	to	IN
cord-306424-gf0bglm0	113	32	IFN	IFN	NNP
cord-306424-gf0bglm0	113	33	production	production	NN
cord-306424-gf0bglm0	113	34	in	in	IN
cord-306424-gf0bglm0	113	35	vitro	vitro	FW
cord-306424-gf0bglm0	113	36	,	,	,
cord-306424-gf0bglm0	113	37	including	include	VBG
cord-306424-gf0bglm0	113	38	RIG	rig	NN
cord-306424-gf0bglm0	113	39	-	-	:
cord-306424-gf0bglm0	113	40	I	I	NNP
cord-306424-gf0bglm0	113	41	,	,	,
cord-306424-gf0bglm0	113	42	MDA5	MDA5	NNP
cord-306424-gf0bglm0	113	43	,	,	,
cord-306424-gf0bglm0	113	44	PKR	PKR	NNP
cord-306424-gf0bglm0	113	45	,	,	,
cord-306424-gf0bglm0	113	46	OAS	OAS	NNP
cord-306424-gf0bglm0	113	47	,	,	,
cord-306424-gf0bglm0	113	48	RNaseL	RNaseL	NNP
cord-306424-gf0bglm0	113	49	,	,	,
cord-306424-gf0bglm0	113	50	and	and	CC
cord-306424-gf0bglm0	113	51	dsRNA	dsrna	NN
cord-306424-gf0bglm0	113	52	[	[	-LRB-
cord-306424-gf0bglm0	113	53	65	65	CD
cord-306424-gf0bglm0	113	54	,	,	,
cord-306424-gf0bglm0	113	55	66	66	CD
cord-306424-gf0bglm0	113	56	]	]	-RRB-
cord-306424-gf0bglm0	113	57	.	.	.
cord-306424-gf0bglm0	114	1	However	however	RB
cord-306424-gf0bglm0	114	2	,	,	,
cord-306424-gf0bglm0	114	3	it	-PRON-	PRP
cord-306424-gf0bglm0	114	4	should	should	MD
cord-306424-gf0bglm0	114	5	be	be	VB
cord-306424-gf0bglm0	114	6	noted	note	VBN
cord-306424-gf0bglm0	114	7	that	that	IN
cord-306424-gf0bglm0	114	8	the	the	DT
cord-306424-gf0bglm0	114	9	contribution	contribution	NN
cord-306424-gf0bglm0	114	10	of	of	IN
cord-306424-gf0bglm0	114	11	SGs	SGs	NNP
cord-306424-gf0bglm0	114	12	to	to	IN
cord-306424-gf0bglm0	114	13	antiviral	antiviral	JJ
cord-306424-gf0bglm0	114	14	signaling	signaling	NN
cord-306424-gf0bglm0	114	15	differs	differ	VBZ
cord-306424-gf0bglm0	114	16	per	per	IN
cord-306424-gf0bglm0	114	17	virus	virus	NN
cord-306424-gf0bglm0	114	18	,	,	,
cord-306424-gf0bglm0	114	19	as	as	IN
cord-306424-gf0bglm0	114	20	SG	SG	NNP
cord-306424-gf0bglm0	114	21	-	-	HYPH
cord-306424-gf0bglm0	114	22	localized	localize	VBN
cord-306424-gf0bglm0	114	23	MDA5	MDA5	NNP
cord-306424-gf0bglm0	114	24	,	,	,
cord-306424-gf0bglm0	114	25	an	an	DT
cord-306424-gf0bglm0	114	26	RLR	RLR	NNP
cord-306424-gf0bglm0	114	27	that	that	WDT
cord-306424-gf0bglm0	114	28	greatly	greatly	RB
cord-306424-gf0bglm0	114	29	contributes	contribute	VBZ
cord-306424-gf0bglm0	114	30	to	to	IN
cord-306424-gf0bglm0	114	31	IFN	IFN	NNP
cord-306424-gf0bglm0	114	32	induction	induction	NN
cord-306424-gf0bglm0	114	33	upon	upon	IN
cord-306424-gf0bglm0	114	34	encephalomyocarditis	encephalomyocarditis	NNP
cord-306424-gf0bglm0	114	35	virus	virus	NN
cord-306424-gf0bglm0	114	36	infection	infection	NN
cord-306424-gf0bglm0	114	37	,	,	,
cord-306424-gf0bglm0	114	38	was	be	VBD
cord-306424-gf0bglm0	114	39	not	not	RB
cord-306424-gf0bglm0	114	40	found	find	VBN
cord-306424-gf0bglm0	114	41	to	to	TO
cord-306424-gf0bglm0	114	42	support	support	VB
cord-306424-gf0bglm0	114	43	IFN	IFN	NNP
cord-306424-gf0bglm0	114	44	expression	expression	NN
cord-306424-gf0bglm0	114	45	upon	upon	IN
cord-306424-gf0bglm0	114	46	infection	infection	NN
cord-306424-gf0bglm0	114	47	with	with	IN
cord-306424-gf0bglm0	114	48	this	this	DT
cord-306424-gf0bglm0	114	49	virus	virus	NN
cord-306424-gf0bglm0	114	50	[	[	-LRB-
cord-306424-gf0bglm0	114	51	67	67	CD
cord-306424-gf0bglm0	114	52	]	]	-RRB-
cord-306424-gf0bglm0	114	53	.	.	.
cord-306424-gf0bglm0	115	1	Nonetheless	nonetheless	RB
cord-306424-gf0bglm0	115	2	,	,	,
cord-306424-gf0bglm0	115	3	these	these	DT
cord-306424-gf0bglm0	115	4	findings	finding	NNS
cord-306424-gf0bglm0	115	5	suggest	suggest	VBP
cord-306424-gf0bglm0	115	6	an	an	DT
cord-306424-gf0bglm0	115	7	important	important	JJ
cord-306424-gf0bglm0	115	8	role	role	NN
cord-306424-gf0bglm0	115	9	for	for	IN
cord-306424-gf0bglm0	115	10	SGs	SGs	NNP
cord-306424-gf0bglm0	115	11	as	as	IN
cord-306424-gf0bglm0	115	12	detection	detection	NN
cord-306424-gf0bglm0	115	13	platforms	platform	NNS
cord-306424-gf0bglm0	115	14	for	for	IN
cord-306424-gf0bglm0	115	15	viral	viral	JJ
cord-306424-gf0bglm0	115	16	RNA	RNA	NNP
cord-306424-gf0bglm0	115	17	.	.	.
cord-306424-gf0bglm0	116	1	Taken	take	VBN
cord-306424-gf0bglm0	116	2	together	together	RB
cord-306424-gf0bglm0	116	3	,	,	,
cord-306424-gf0bglm0	116	4	increasing	increase	VBG
cord-306424-gf0bglm0	116	5	evidence	evidence	NN
cord-306424-gf0bglm0	116	6	suggests	suggest	VBZ
cord-306424-gf0bglm0	116	7	that	that	IN
cord-306424-gf0bglm0	116	8	the	the	DT
cord-306424-gf0bglm0	116	9	antiviral	antiviral	JJ
cord-306424-gf0bglm0	116	10	innate	innate	JJ
cord-306424-gf0bglm0	116	11	immune	immune	JJ
cord-306424-gf0bglm0	116	12	signaling	signal	VBG
cord-306424-gf0bglm0	116	13	cascade	cascade	NN
cord-306424-gf0bglm0	116	14	is	be	VBZ
cord-306424-gf0bglm0	116	15	spatially	spatially	RB
cord-306424-gf0bglm0	116	16	organized	organize	VBN
cord-306424-gf0bglm0	116	17	,	,	,
cord-306424-gf0bglm0	116	18	and	and	CC
cord-306424-gf0bglm0	116	19	since	since	IN
cord-306424-gf0bglm0	116	20	different	different	JJ
cord-306424-gf0bglm0	116	21	structures	structure	NNS
cord-306424-gf0bglm0	116	22	in	in	IN
cord-306424-gf0bglm0	116	23	the	the	DT
cord-306424-gf0bglm0	116	24	cell	cell	NN
cord-306424-gf0bglm0	116	25	seem	seem	VBP
cord-306424-gf0bglm0	116	26	to	to	TO
cord-306424-gf0bglm0	116	27	be	be	VB
cord-306424-gf0bglm0	116	28	specialized	specialize	VBN
cord-306424-gf0bglm0	116	29	in	in	IN
cord-306424-gf0bglm0	116	30	a	a	DT
cord-306424-gf0bglm0	116	31	particular	particular	JJ
cord-306424-gf0bglm0	116	32	aspect	aspect	NN
cord-306424-gf0bglm0	116	33	of	of	IN
cord-306424-gf0bglm0	116	34	this	this	DT
cord-306424-gf0bglm0	116	35	process	process	NN
cord-306424-gf0bglm0	116	36	,	,	,
cord-306424-gf0bglm0	116	37	it	-PRON-	PRP
cord-306424-gf0bglm0	116	38	can	can	MD
cord-306424-gf0bglm0	116	39	be	be	VB
cord-306424-gf0bglm0	116	40	hypothesized	hypothesize	VBN
cord-306424-gf0bglm0	116	41	that	that	IN
cord-306424-gf0bglm0	116	42	interaction	interaction	NN
cord-306424-gf0bglm0	116	43	between	between	IN
cord-306424-gf0bglm0	116	44	these	these	DT
cord-306424-gf0bglm0	116	45	structures	structure	NNS
cord-306424-gf0bglm0	116	46	plays	play	VBZ
cord-306424-gf0bglm0	116	47	a	a	DT
cord-306424-gf0bglm0	116	48	fundamental	fundamental	JJ
cord-306424-gf0bglm0	116	49	role	role	NN
cord-306424-gf0bglm0	116	50	in	in	IN
cord-306424-gf0bglm0	116	51	orchestrating	orchestrate	VBG
cord-306424-gf0bglm0	116	52	the	the	DT
cord-306424-gf0bglm0	116	53	antiviral	antiviral	JJ
cord-306424-gf0bglm0	116	54	innate	innate	JJ
cord-306424-gf0bglm0	116	55	immune	immune	JJ
cord-306424-gf0bglm0	116	56	response	response	NN
cord-306424-gf0bglm0	116	57	.	.	.
cord-306424-gf0bglm0	117	1	Positive	positive	JJ
cord-306424-gf0bglm0	117	2	-	-	HYPH
cord-306424-gf0bglm0	117	3	strand	strand	NN
cord-306424-gf0bglm0	117	4	RNA	RNA	NNP
cord-306424-gf0bglm0	117	5	viruses	virus	NNS
cord-306424-gf0bglm0	117	6	developed	develop	VBD
cord-306424-gf0bglm0	117	7	multiple	multiple	JJ
cord-306424-gf0bglm0	117	8	mechanisms	mechanism	NNS
cord-306424-gf0bglm0	117	9	to	to	TO
cord-306424-gf0bglm0	117	10	impair	impair	VB
cord-306424-gf0bglm0	117	11	RNA	RNA	NNP
cord-306424-gf0bglm0	117	12	recognition	recognition	NN
cord-306424-gf0bglm0	117	13	and	and	CC
cord-306424-gf0bglm0	117	14	antiviral	antiviral	JJ
cord-306424-gf0bglm0	117	15	signaling	signaling	NN
cord-306424-gf0bglm0	117	16	(	(	-LRB-
cord-306424-gf0bglm0	117	17	also	also	RB
cord-306424-gf0bglm0	117	18	reviewed	review	VBN
cord-306424-gf0bglm0	117	19	in	in	IN
cord-306424-gf0bglm0	117	20	[	[	-LRB-
cord-306424-gf0bglm0	117	21	8	8	CD
cord-306424-gf0bglm0	117	22	]	]	-RRB-
cord-306424-gf0bglm0	117	23	)	)	-RRB-
cord-306424-gf0bglm0	117	24	.	.	.
cord-306424-gf0bglm0	118	1	As	as	IN
cord-306424-gf0bglm0	118	2	mentioned	mention	VBN
cord-306424-gf0bglm0	118	3	above	above	RB
cord-306424-gf0bglm0	118	4	,	,	,
cord-306424-gf0bglm0	118	5	the	the	DT
cord-306424-gf0bglm0	118	6	presence	presence	NN
cord-306424-gf0bglm0	118	7	of	of	IN
cord-306424-gf0bglm0	118	8	viral	viral	JJ
cord-306424-gf0bglm0	118	9	RNA	RNA	NNP
cord-306424-gf0bglm0	118	10	in	in	IN
cord-306424-gf0bglm0	118	11	ROs	ROs	NNP
cord-306424-gf0bglm0	118	12	suggests	suggest	VBZ
cord-306424-gf0bglm0	118	13	a	a	DT
cord-306424-gf0bglm0	118	14	role	role	NN
cord-306424-gf0bglm0	118	15	for	for	IN
cord-306424-gf0bglm0	118	16	ROs	ROs	NNP
cord-306424-gf0bglm0	118	17	in	in	IN
cord-306424-gf0bglm0	118	18	shielding	shield	VBG
cord-306424-gf0bglm0	118	19	viral	viral	JJ
cord-306424-gf0bglm0	118	20	RNA	RNA	NNP
cord-306424-gf0bglm0	118	21	from	from	IN
cord-306424-gf0bglm0	118	22	the	the	DT
cord-306424-gf0bglm0	118	23	innate	innate	JJ
cord-306424-gf0bglm0	118	24	immune	immune	JJ
cord-306424-gf0bglm0	118	25	detection	detection	NN
cord-306424-gf0bglm0	118	26	machinery	machinery	NN
cord-306424-gf0bglm0	118	27	.	.	.
cord-306424-gf0bglm0	119	1	While	while	IN
cord-306424-gf0bglm0	119	2	there	there	EX
cord-306424-gf0bglm0	119	3	is	be	VBZ
cord-306424-gf0bglm0	119	4	no	no	DT
cord-306424-gf0bglm0	119	5	unequivocal	unequivocal	JJ
cord-306424-gf0bglm0	119	6	evidence	evidence	NN
cord-306424-gf0bglm0	119	7	supporting	support	VBG
cord-306424-gf0bglm0	119	8	this	this	DT
cord-306424-gf0bglm0	119	9	theory	theory	NN
cord-306424-gf0bglm0	119	10	,	,	,
cord-306424-gf0bglm0	119	11	the	the	DT
cord-306424-gf0bglm0	119	12	finding	finding	NN
cord-306424-gf0bglm0	119	13	that	that	WDT
cord-306424-gf0bglm0	119	14	isolated	isolate	VBD
cord-306424-gf0bglm0	119	15	viral	viral	JJ
cord-306424-gf0bglm0	119	16	RNAcontaining	rnacontaine	VBG
cord-306424-gf0bglm0	119	17	membrane	membrane	NN
cord-306424-gf0bglm0	119	18	alterations	alteration	NNS
cord-306424-gf0bglm0	119	19	only	only	RB
cord-306424-gf0bglm0	119	20	become	become	VBP
cord-306424-gf0bglm0	119	21	sensitive	sensitive	JJ
cord-306424-gf0bglm0	119	22	to	to	IN
cord-306424-gf0bglm0	119	23	nuclease	nuclease	NN
cord-306424-gf0bglm0	119	24	treatment	treatment	NN
cord-306424-gf0bglm0	119	25	after	after	IN
cord-306424-gf0bglm0	119	26	membrane	membrane	NN
cord-306424-gf0bglm0	119	27	disruption	disruption	NN
cord-306424-gf0bglm0	119	28	by	by	IN
cord-306424-gf0bglm0	119	29	nonionic	nonionic	JJ
cord-306424-gf0bglm0	119	30	detergents	detergent	NNS
cord-306424-gf0bglm0	119	31	supports	support	VBZ
cord-306424-gf0bglm0	119	32	this	this	DT
cord-306424-gf0bglm0	119	33	hypothesis	hypothesis	NN
cord-306424-gf0bglm0	119	34	[	[	-LRB-
cord-306424-gf0bglm0	119	35	68	68	CD
cord-306424-gf0bglm0	119	36	]	]	-RRB-
cord-306424-gf0bglm0	119	37	[	[	-LRB-
cord-306424-gf0bglm0	119	38	69	69	CD
cord-306424-gf0bglm0	119	39	]	]	-RRB-
cord-306424-gf0bglm0	119	40	[	[	-LRB-
cord-306424-gf0bglm0	119	41	70	70	CD
cord-306424-gf0bglm0	119	42	]	]	-RRB-
cord-306424-gf0bglm0	119	43	[	[	-LRB-
cord-306424-gf0bglm0	119	44	71	71	CD
cord-306424-gf0bglm0	119	45	]	]	-RRB-
cord-306424-gf0bglm0	119	46	.	.	.
cord-306424-gf0bglm0	120	1	In	in	IN
cord-306424-gf0bglm0	120	2	addition	addition	NN
cord-306424-gf0bglm0	120	3	,	,	,
cord-306424-gf0bglm0	120	4	a	a	DT
cord-306424-gf0bglm0	120	5	positive	positive	JJ
cord-306424-gf0bglm0	120	6	correlation	correlation	NN
cord-306424-gf0bglm0	120	7	between	between	IN
cord-306424-gf0bglm0	120	8	cytosolic	cytosolic	JJ
cord-306424-gf0bglm0	120	9	exposure	exposure	NN
cord-306424-gf0bglm0	120	10	of	of	IN
cord-306424-gf0bglm0	120	11	viral	viral	JJ
cord-306424-gf0bglm0	120	12	RNA	RNA	NNP
cord-306424-gf0bglm0	120	13	and	and	CC
cord-306424-gf0bglm0	120	14	IFN	IFN	NNP
cord-306424-gf0bglm0	120	15	induction	induction	NN
cord-306424-gf0bglm0	120	16	was	be	VBD
cord-306424-gf0bglm0	120	17	recently	recently	RB
cord-306424-gf0bglm0	120	18	found	find	VBN
cord-306424-gf0bglm0	120	19	by	by	IN
cord-306424-gf0bglm0	120	20	an	an	DT
cord-306424-gf0bglm0	120	21	in	in	FW
cord-306424-gf0bglm0	120	22	vitro	vitro	FW
cord-306424-gf0bglm0	120	23	comparison	comparison	NN
cord-306424-gf0bglm0	120	24	of	of	IN
cord-306424-gf0bglm0	120	25	JEV	JEV	NNP
cord-306424-gf0bglm0	120	26	and	and	CC
cord-306424-gf0bglm0	120	27	DENV	DENV	NNP
cord-306424-gf0bglm0	120	28	infections	infection	NNS
cord-306424-gf0bglm0	120	29	[	[	-LRB-
cord-306424-gf0bglm0	120	30	72	72	CD
cord-306424-gf0bglm0	120	31	]	]	-RRB-
cord-306424-gf0bglm0	120	32	.	.	.
cord-306424-gf0bglm0	121	1	Another	another	DT
cord-306424-gf0bglm0	121	2	important	important	JJ
cord-306424-gf0bglm0	121	3	strategy	strategy	NN
cord-306424-gf0bglm0	121	4	by	by	IN
cord-306424-gf0bglm0	121	5	which	which	WDT
cord-306424-gf0bglm0	121	6	RNA	RNA	NNP
cord-306424-gf0bglm0	121	7	viruses	virus	NNS
cord-306424-gf0bglm0	121	8	avoid	avoid	VBP
cord-306424-gf0bglm0	121	9	recognition	recognition	NN
cord-306424-gf0bglm0	121	10	is	be	VBZ
cord-306424-gf0bglm0	121	11	their	-PRON-	PRP$
cord-306424-gf0bglm0	121	12	modification	modification	NN
cord-306424-gf0bglm0	121	13	of	of	IN
cord-306424-gf0bglm0	121	14	viral	viral	JJ
cord-306424-gf0bglm0	121	15	RNA	RNA	NNP
cord-306424-gf0bglm0	121	16	molecules	molecule	NNS
cord-306424-gf0bglm0	121	17	to	to	TO
cord-306424-gf0bglm0	121	18	mimic	mimic	VB
cord-306424-gf0bglm0	121	19	eukaryotic	eukaryotic	JJ
cord-306424-gf0bglm0	121	20	mRNA	mrna	NN
cord-306424-gf0bglm0	121	21	.	.	.
cord-306424-gf0bglm0	122	1	For	for	IN
cord-306424-gf0bglm0	122	2	example	example	NN
cord-306424-gf0bglm0	122	3	,	,	,
cord-306424-gf0bglm0	122	4	the	the	DT
cord-306424-gf0bglm0	122	5	formation	formation	NN
cord-306424-gf0bglm0	122	6	of	of	IN
cord-306424-gf0bglm0	122	7	a	a	DT
cord-306424-gf0bglm0	122	8	5	5	CD
cord-306424-gf0bglm0	122	9	0	0	CD
cord-306424-gf0bglm0	122	10	cap	cap	NN
cord-306424-gf0bglm0	122	11	is	be	VBZ
cord-306424-gf0bglm0	122	12	catalyzed	catalyze	VBN
cord-306424-gf0bglm0	122	13	by	by	IN
cord-306424-gf0bglm0	122	14	viral	viral	JJ
cord-306424-gf0bglm0	122	15	phosphatases	phosphatase	NNS
cord-306424-gf0bglm0	122	16	and	and	CC
cord-306424-gf0bglm0	122	17	methyltransferases	methyltransferase	NNS
cord-306424-gf0bglm0	122	18	in	in	IN
cord-306424-gf0bglm0	122	19	some	some	DT
cord-306424-gf0bglm0	122	20	viral	viral	JJ
cord-306424-gf0bglm0	122	21	families	family	NNS
cord-306424-gf0bglm0	122	22	such	such	JJ
cord-306424-gf0bglm0	122	23	as	as	IN
cord-306424-gf0bglm0	122	24	the	the	DT
cord-306424-gf0bglm0	122	25	coronaviruses	coronaviruse	NNS
cord-306424-gf0bglm0	122	26	.	.	.
cord-306424-gf0bglm0	123	1	From	from	IN
cord-306424-gf0bglm0	123	2	work	work	NN
cord-306424-gf0bglm0	123	3	on	on	IN
cord-306424-gf0bglm0	123	4	mouse	mouse	NN
cord-306424-gf0bglm0	123	5	hepatitis	hepatitis	NNP
cord-306424-gf0bglm0	123	6	virus	virus	NN
cord-306424-gf0bglm0	123	7	(	(	-LRB-
cord-306424-gf0bglm0	123	8	MHV	MHV	NNP
cord-306424-gf0bglm0	123	9	)	)	-RRB-
cord-306424-gf0bglm0	123	10	it	-PRON-	PRP
cord-306424-gf0bglm0	123	11	became	become	VBD
cord-306424-gf0bglm0	123	12	clear	clear	JJ
cord-306424-gf0bglm0	123	13	that	that	IN
cord-306424-gf0bglm0	123	14	coronaviruses	coronaviruse	NNS
cord-306424-gf0bglm0	123	15	need	need	VBP
cord-306424-gf0bglm0	123	16	to	to	TO
cord-306424-gf0bglm0	123	17	take	take	VB
cord-306424-gf0bglm0	123	18	care	care	NN
cord-306424-gf0bglm0	123	19	of	of	IN
cord-306424-gf0bglm0	123	20	N	n	NN
cord-306424-gf0bglm0	123	21	-	-	HYPH
cord-306424-gf0bglm0	123	22	linked	link	VBN
cord-306424-gf0bglm0	123	23	as	as	RB
cord-306424-gf0bglm0	123	24	well	well	RB
cord-306424-gf0bglm0	123	25	as	as	IN
cord-306424-gf0bglm0	123	26	2	2	CD
cord-306424-gf0bglm0	123	27	0	0	CD
cord-306424-gf0bglm0	123	28	O	o	NN
cord-306424-gf0bglm0	123	29	-	-	HYPH
cord-306424-gf0bglm0	123	30	linked	link	VBN
cord-306424-gf0bglm0	123	31	methylation	methylation	NN
cord-306424-gf0bglm0	123	32	on	on	IN
cord-306424-gf0bglm0	123	33	the	the	DT
cord-306424-gf0bglm0	123	34	CAP	cap	NN
cord-306424-gf0bglm0	123	35	structure	structure	NN
cord-306424-gf0bglm0	123	36	,	,	,
cord-306424-gf0bglm0	123	37	in	in	IN
cord-306424-gf0bglm0	123	38	order	order	NN
cord-306424-gf0bglm0	123	39	to	to	TO
cord-306424-gf0bglm0	123	40	avoid	avoid	VB
cord-306424-gf0bglm0	123	41	recognition	recognition	NN
cord-306424-gf0bglm0	123	42	by	by	IN
cord-306424-gf0bglm0	123	43	innate	innate	JJ
cord-306424-gf0bglm0	123	44	immune	immune	JJ
cord-306424-gf0bglm0	123	45	sensors	sensor	NNS
cord-306424-gf0bglm0	123	46	[	[	-LRB-
cord-306424-gf0bglm0	123	47	73	73	CD
cord-306424-gf0bglm0	123	48	]	]	-RRB-
cord-306424-gf0bglm0	123	49	.	.	.
cord-306424-gf0bglm0	124	1	Mimicry	Mimicry	NNP
cord-306424-gf0bglm0	124	2	of	of	IN
cord-306424-gf0bglm0	124	3	eukaryotic	eukaryotic	JJ
cord-306424-gf0bglm0	124	4	RNA	RNA	NNP
cord-306424-gf0bglm0	124	5	in	in	IN
cord-306424-gf0bglm0	124	6	this	this	DT
cord-306424-gf0bglm0	124	7	way	way	NN
cord-306424-gf0bglm0	124	8	was	be	VBD
cord-306424-gf0bglm0	124	9	shown	show	VBN
cord-306424-gf0bglm0	124	10	to	to	TO
cord-306424-gf0bglm0	124	11	be	be	VB
cord-306424-gf0bglm0	124	12	an	an	DT
cord-306424-gf0bglm0	124	13	important	important	JJ
cord-306424-gf0bglm0	124	14	immune	immune	JJ
cord-306424-gf0bglm0	124	15	evasion	evasion	NN
cord-306424-gf0bglm0	124	16	strategy	strategy	NN
cord-306424-gf0bglm0	124	17	by	by	IN
cord-306424-gf0bglm0	124	18	+	+	SYM
cord-306424-gf0bglm0	124	19	RNA	RNA	NNP
cord-306424-gf0bglm0	124	20	viruses	virus	NNS
cord-306424-gf0bglm0	124	21	such	such	JJ
cord-306424-gf0bglm0	124	22	as	as	IN
cord-306424-gf0bglm0	124	23	SARS	SARS	NNP
cord-306424-gf0bglm0	124	24	-	-	HYPH
cord-306424-gf0bglm0	124	25	CoV	CoV	NNP
cord-306424-gf0bglm0	124	26	and	and	CC
cord-306424-gf0bglm0	124	27	JEV	JEV	NNP
cord-306424-gf0bglm0	125	1	[	[	-LRB-
cord-306424-gf0bglm0	125	2	74	74	CD
cord-306424-gf0bglm0	125	3	,	,	,
cord-306424-gf0bglm0	125	4	75	75	CD
cord-306424-gf0bglm0	125	5	]	]	-RRB-
cord-306424-gf0bglm0	125	6	.	.	.
cord-306424-gf0bglm0	126	1	A	a	DT
cord-306424-gf0bglm0	126	2	recent	recent	JJ
cord-306424-gf0bglm0	126	3	report	report	NN
cord-306424-gf0bglm0	126	4	indicated	indicate	VBD
cord-306424-gf0bglm0	126	5	that	that	IN
cord-306424-gf0bglm0	126	6	coronaviruses	coronaviruse	NNS
cord-306424-gf0bglm0	126	7	also	also	RB
cord-306424-gf0bglm0	126	8	evade	evade	VBP
cord-306424-gf0bglm0	126	9	dsRNA	dsrna	JJ
cord-306424-gf0bglm0	126	10	mediated	mediate	VBN
cord-306424-gf0bglm0	126	11	recognition	recognition	NN
cord-306424-gf0bglm0	126	12	by	by	IN
cord-306424-gf0bglm0	126	13	PKR	PKR	NNP
cord-306424-gf0bglm0	126	14	and	and	CC
cord-306424-gf0bglm0	126	15	OAS	OAS	NNP
cord-306424-gf0bglm0	126	16	by	by	IN
cord-306424-gf0bglm0	126	17	using	use	VBG
cord-306424-gf0bglm0	126	18	their	-PRON-	PRP$
cord-306424-gf0bglm0	126	19	endonuclease	endonuclease	NN
cord-306424-gf0bglm0	126	20	(	(	-LRB-
cord-306424-gf0bglm0	126	21	EndoU	EndoU	NNP
cord-306424-gf0bglm0	126	22	)	)	-RRB-
cord-306424-gf0bglm0	126	23	,	,	,
cord-306424-gf0bglm0	126	24	which	which	WDT
cord-306424-gf0bglm0	126	25	cleaves	cleave	VBZ
cord-306424-gf0bglm0	126	26	free	free	JJ
cord-306424-gf0bglm0	126	27	viral	viral	NN
cord-306424-gf0bglm0	126	28	(	(	-LRB-
cord-306424-gf0bglm0	126	29	and	and	CC
cord-306424-gf0bglm0	126	30	cellular	cellular	JJ
cord-306424-gf0bglm0	126	31	)	)	-RRB-
cord-306424-gf0bglm0	126	32	RNA	rna	NN
cord-306424-gf0bglm0	126	33	that	that	WDT
cord-306424-gf0bglm0	126	34	is	be	VBZ
cord-306424-gf0bglm0	126	35	somehow	somehow	RB
cord-306424-gf0bglm0	126	36	exposed	expose	VBN
cord-306424-gf0bglm0	126	37	to	to	IN
cord-306424-gf0bglm0	126	38	the	the	DT
cord-306424-gf0bglm0	126	39	cytosol	cytosol	NN
cord-306424-gf0bglm0	126	40	,	,	,
cord-306424-gf0bglm0	126	41	in	in	IN
cord-306424-gf0bglm0	126	42	order	order	NN
cord-306424-gf0bglm0	126	43	to	to	TO
cord-306424-gf0bglm0	126	44	prevent	prevent	VB
cord-306424-gf0bglm0	126	45	antiviral	antiviral	JJ
cord-306424-gf0bglm0	126	46	signaling	signal	VBG
cord-306424-gf0bglm0	126	47	[	[	-LRB-
cord-306424-gf0bglm0	126	48	76	76	CD
cord-306424-gf0bglm0	126	49	]	]	-RRB-
cord-306424-gf0bglm0	126	50	.	.	.
cord-306424-gf0bglm0	127	1	In	in	IN
cord-306424-gf0bglm0	127	2	addition	addition	NN
cord-306424-gf0bglm0	127	3	to	to	IN
cord-306424-gf0bglm0	127	4	avoidance	avoidance	NN
cord-306424-gf0bglm0	127	5	of	of	IN
cord-306424-gf0bglm0	127	6	recognition	recognition	NN
cord-306424-gf0bglm0	127	7	,	,	,
cord-306424-gf0bglm0	127	8	+	+	CC
cord-306424-gf0bglm0	127	9	RNA	rna	NN
cord-306424-gf0bglm0	127	10	viruses	virus	NNS
cord-306424-gf0bglm0	127	11	actively	actively	RB
cord-306424-gf0bglm0	127	12	interfere	interfere	VBP
cord-306424-gf0bglm0	127	13	with	with	IN
cord-306424-gf0bglm0	127	14	antiviral	antiviral	JJ
cord-306424-gf0bglm0	127	15	signaling	signal	VBG
cord-306424-gf0bglm0	127	16	components	component	NNS
cord-306424-gf0bglm0	127	17	to	to	TO
cord-306424-gf0bglm0	127	18	impair	impair	VB
cord-306424-gf0bglm0	127	19	expression	expression	NN
cord-306424-gf0bglm0	127	20	of	of	IN
cord-306424-gf0bglm0	127	21	IFNs	ifn	NNS
cord-306424-gf0bglm0	127	22	and	and	CC
cord-306424-gf0bglm0	127	23	pro	pro	JJ
cord-306424-gf0bglm0	127	24	-	-	JJ
cord-306424-gf0bglm0	127	25	inflammatory	inflammatory	JJ
cord-306424-gf0bglm0	127	26	cytokines	cytokine	NNS
cord-306424-gf0bglm0	127	27	.	.	.
cord-306424-gf0bglm0	128	1	Very	very	RB
cord-306424-gf0bglm0	128	2	often	often	RB
cord-306424-gf0bglm0	128	3	,	,	,
cord-306424-gf0bglm0	128	4	the	the	DT
cord-306424-gf0bglm0	128	5	viral	viral	JJ
cord-306424-gf0bglm0	128	6	proteases	protease	NNS
cord-306424-gf0bglm0	128	7	that	that	WDT
cord-306424-gf0bglm0	128	8	are	be	VBP
cord-306424-gf0bglm0	128	9	expressed	express	VBN
cord-306424-gf0bglm0	128	10	by	by	IN
cord-306424-gf0bglm0	128	11	+	+	SYM
cord-306424-gf0bglm0	128	12	RNA	RNA	NNP
cord-306424-gf0bglm0	128	13	viruses	virus	NNS
cord-306424-gf0bglm0	128	14	,	,	,
cord-306424-gf0bglm0	128	15	and	and	CC
cord-306424-gf0bglm0	128	16	which	which	WDT
cord-306424-gf0bglm0	128	17	mostly	mostly	RB
cord-306424-gf0bglm0	128	18	have	have	VBP
cord-306424-gf0bglm0	128	19	a	a	DT
cord-306424-gf0bglm0	128	20	primary	primary	JJ
cord-306424-gf0bglm0	128	21	function	function	NN
cord-306424-gf0bglm0	128	22	in	in	IN
cord-306424-gf0bglm0	128	23	cleavage	cleavage	NN
cord-306424-gf0bglm0	128	24	of	of	IN
cord-306424-gf0bglm0	128	25	viral	viral	JJ
cord-306424-gf0bglm0	128	26	replicase	replicase	NN
cord-306424-gf0bglm0	128	27	polyproteins	polyprotein	NNS
cord-306424-gf0bglm0	128	28	,	,	,
cord-306424-gf0bglm0	128	29	seem	seem	VBP
cord-306424-gf0bglm0	128	30	to	to	TO
cord-306424-gf0bglm0	128	31	have	have	VB
cord-306424-gf0bglm0	128	32	a	a	DT
cord-306424-gf0bglm0	128	33	prominent	prominent	JJ
cord-306424-gf0bglm0	128	34	role	role	NN
cord-306424-gf0bglm0	128	35	in	in	IN
cord-306424-gf0bglm0	128	36	this	this	DT
cord-306424-gf0bglm0	128	37	.	.	.
cord-306424-gf0bglm0	129	1	For	for	IN
cord-306424-gf0bglm0	129	2	example	example	NN
cord-306424-gf0bglm0	129	3	,	,	,
cord-306424-gf0bglm0	129	4	HCV	HCV	NNP
cord-306424-gf0bglm0	129	5	NS3/4A	ns3/4a	NN
cord-306424-gf0bglm0	129	6	and	and	CC
cord-306424-gf0bglm0	129	7	DENV	DENV	NNP
cord-306424-gf0bglm0	129	8	NS4A	NS4A	NNP
cord-306424-gf0bglm0	129	9	cleave	cleave	VBP
cord-306424-gf0bglm0	129	10	MAVS	MAVS	NNPS
cord-306424-gf0bglm0	129	11	[	[	-LRB-
cord-306424-gf0bglm0	129	12	47	47	CD
cord-306424-gf0bglm0	129	13	,	,	,
cord-306424-gf0bglm0	129	14	[	[	-LRB-
cord-306424-gf0bglm0	129	15	77	77	CD
cord-306424-gf0bglm0	129	16	]	]	-RRB-
cord-306424-gf0bglm0	129	17	[	[	-LRB-
cord-306424-gf0bglm0	129	18	78	78	CD
cord-306424-gf0bglm0	129	19	]	]	-RRB-
cord-306424-gf0bglm0	129	20	[	[	-LRB-
cord-306424-gf0bglm0	129	21	79	79	CD
cord-306424-gf0bglm0	129	22	]	]	-RRB-
cord-306424-gf0bglm0	130	1	[	[	-LRB-
cord-306424-gf0bglm0	130	2	80	80	CD
cord-306424-gf0bglm0	130	3	]	]	-RRB-
cord-306424-gf0bglm0	131	1	[	[	-LRB-
cord-306424-gf0bglm0	131	2	81	81	CD
cord-306424-gf0bglm0	131	3	]	]	-RRB-
cord-306424-gf0bglm0	131	4	[	[	-LRB-
cord-306424-gf0bglm0	131	5	82	82	CD
cord-306424-gf0bglm0	131	6	]	]	-RRB-
cord-306424-gf0bglm0	131	7	,	,	,
cord-306424-gf0bglm0	131	8	and	and	CC
cord-306424-gf0bglm0	131	9	the	the	DT
cord-306424-gf0bglm0	131	10	DENV	DENV	NNP
cord-306424-gf0bglm0	131	11	protease	protease	NN
cord-306424-gf0bglm0	131	12	complex	complex	NN
cord-306424-gf0bglm0	131	13	and	and	CC
cord-306424-gf0bglm0	131	14	HCV	HCV	NNP
cord-306424-gf0bglm0	132	1	NS4B	ns4b	DT
cord-306424-gf0bglm0	132	2	inhibit	inhibit	VBP
cord-306424-gf0bglm0	132	3	adaptor	adaptor	NN
cord-306424-gf0bglm0	132	4	molecule	molecule	NN
cord-306424-gf0bglm0	132	5	STING	sting	NN
cord-306424-gf0bglm0	132	6	by	by	IN
cord-306424-gf0bglm0	132	7	cleaving	cleave	VBG
cord-306424-gf0bglm0	132	8	it	-PRON-	PRP
cord-306424-gf0bglm0	132	9	[	[	-LRB-
cord-306424-gf0bglm0	132	10	83	83	CD
cord-306424-gf0bglm0	132	11	]	]	-RRB-
cord-306424-gf0bglm0	132	12	[	[	-LRB-
cord-306424-gf0bglm0	132	13	84	84	CD
cord-306424-gf0bglm0	132	14	]	]	-RRB-
cord-306424-gf0bglm0	132	15	[	[	-LRB-
cord-306424-gf0bglm0	132	16	85	85	CD
cord-306424-gf0bglm0	132	17	]	]	-RRB-
cord-306424-gf0bglm0	132	18	[	[	-LRB-
cord-306424-gf0bglm0	132	19	86	86	CD
cord-306424-gf0bglm0	132	20	]	]	-RRB-
cord-306424-gf0bglm0	132	21	[	[	-LRB-
cord-306424-gf0bglm0	132	22	87	87	CD
cord-306424-gf0bglm0	132	23	]	]	-RRB-
cord-306424-gf0bglm0	132	24	.	.	.
cord-306424-gf0bglm0	133	1	Additionally	additionally	RB
cord-306424-gf0bglm0	133	2	,	,	,
cord-306424-gf0bglm0	133	3	human	human	JJ
cord-306424-gf0bglm0	133	4	CoV	cov	NN
cord-306424-gf0bglm0	133	5	NL63	NL63	NNP
cord-306424-gf0bglm0	133	6	and	and	CC
cord-306424-gf0bglm0	133	7	SARS	SARS	NNP
cord-306424-gf0bglm0	133	8	-	-	HYPH
cord-306424-gf0bglm0	133	9	CoV	CoV	NNP
cord-306424-gf0bglm0	133	10	nsp3	nsp3	NNS
cord-306424-gf0bglm0	133	11	possess	possess	VBP
cord-306424-gf0bglm0	133	12	a	a	DT
cord-306424-gf0bglm0	133	13	papain	papain	NN
cord-306424-gf0bglm0	133	14	-	-	HYPH
cord-306424-gf0bglm0	133	15	like	like	JJ
cord-306424-gf0bglm0	133	16	protease	protease	NN
cord-306424-gf0bglm0	133	17	(	(	-LRB-
cord-306424-gf0bglm0	133	18	PLP	PLP	NNP
cord-306424-gf0bglm0	133	19	)	)	-RRB-
cord-306424-gf0bglm0	133	20	domain	domain	NN
cord-306424-gf0bglm0	133	21	that	that	WDT
cord-306424-gf0bglm0	133	22	prevents	prevent	VBZ
cord-306424-gf0bglm0	133	23	dimerization	dimerization	NN
cord-306424-gf0bglm0	133	24	of	of	IN
cord-306424-gf0bglm0	133	25	STING	sting	NN
cord-306424-gf0bglm0	133	26	and	and	CC
cord-306424-gf0bglm0	133	27	its	-PRON-	PRP$
cord-306424-gf0bglm0	133	28	complex	complex	JJ
cord-306424-gf0bglm0	133	29	formation	formation	NN
cord-306424-gf0bglm0	133	30	with	with	IN
cord-306424-gf0bglm0	133	31	MAVS	MAVS	NNPS
cord-306424-gf0bglm0	133	32	and	and	CC
cord-306424-gf0bglm0	133	33	IKKe	IKKe	NNS
cord-306424-gf0bglm0	133	34	,	,	,
cord-306424-gf0bglm0	133	35	and	and	CC
cord-306424-gf0bglm0	133	36	almost	almost	RB
cord-306424-gf0bglm0	133	37	all	all	DT
cord-306424-gf0bglm0	133	38	nidovirus	nidovirus	NN
cord-306424-gf0bglm0	133	39	-	-	HYPH
cord-306424-gf0bglm0	133	40	encoded	encode	VBN
cord-306424-gf0bglm0	133	41	PLPs	plp	NNS
cord-306424-gf0bglm0	133	42	have	have	VBP
cord-306424-gf0bglm0	133	43	been	be	VBN
cord-306424-gf0bglm0	133	44	shown	show	VBN
cord-306424-gf0bglm0	133	45	to	to	TO
cord-306424-gf0bglm0	133	46	display	display	VB
cord-306424-gf0bglm0	133	47	deubiquitinating	deubiquitinating	NN
cord-306424-gf0bglm0	133	48	activity	activity	NN
cord-306424-gf0bglm0	133	49	[	[	-LRB-
cord-306424-gf0bglm0	133	50	88	88	CD
cord-306424-gf0bglm0	133	51	]	]	-RRB-
cord-306424-gf0bglm0	133	52	.	.	.
cord-306424-gf0bglm0	134	1	Several	several	JJ
cord-306424-gf0bglm0	134	2	have	have	VBP
cord-306424-gf0bglm0	134	3	been	be	VBN
cord-306424-gf0bglm0	134	4	suggested	suggest	VBN
cord-306424-gf0bglm0	134	5	to	to	TO
cord-306424-gf0bglm0	134	6	facilitate	facilitate	VB
cord-306424-gf0bglm0	134	7	deubiquitination	deubiquitination	NN
cord-306424-gf0bglm0	134	8	of	of	IN
cord-306424-gf0bglm0	134	9	innate	innate	JJ
cord-306424-gf0bglm0	134	10	immune	immune	JJ
cord-306424-gf0bglm0	134	11	factors	factor	NNS
cord-306424-gf0bglm0	134	12	such	such	JJ
cord-306424-gf0bglm0	134	13	as	as	IN
cord-306424-gf0bglm0	134	14	STING	sting	NN
cord-306424-gf0bglm0	134	15	,	,	,
cord-306424-gf0bglm0	134	16	RIG	rig	NN
cord-306424-gf0bglm0	134	17	-	-	:
cord-306424-gf0bglm0	134	18	I	I	NNP
cord-306424-gf0bglm0	134	19	,	,	,
cord-306424-gf0bglm0	134	20	TBK1	TBK1	NNP
cord-306424-gf0bglm0	134	21	and	and	CC
cord-306424-gf0bglm0	134	22	IRF3	IRF3	NNP
cord-306424-gf0bglm0	134	23	in	in	IN
cord-306424-gf0bglm0	134	24	order	order	NN
cord-306424-gf0bglm0	134	25	to	to	TO
cord-306424-gf0bglm0	134	26	halt	halt	VB
cord-306424-gf0bglm0	134	27	innate	innate	JJ
cord-306424-gf0bglm0	134	28	immune	immune	NN
cord-306424-gf0bglm0	134	29	signaling	signal	VBG
cord-306424-gf0bglm0	134	30	[	[	-LRB-
cord-306424-gf0bglm0	134	31	8	8	CD
cord-306424-gf0bglm0	134	32	]	]	-RRB-
cord-306424-gf0bglm0	134	33	.	.	.
cord-306424-gf0bglm0	135	1	Moreover	moreover	RB
cord-306424-gf0bglm0	135	2	,	,	,
cord-306424-gf0bglm0	135	3	in	in	IN
cord-306424-gf0bglm0	135	4	collaboration	collaboration	NN
cord-306424-gf0bglm0	135	5	with	with	IN
cord-306424-gf0bglm0	135	6	others	other	NNS
cord-306424-gf0bglm0	135	7	,	,	,
cord-306424-gf0bglm0	135	8	our	-PRON-	PRP$
cord-306424-gf0bglm0	135	9	lab	lab	NN
cord-306424-gf0bglm0	135	10	demonstrated	demonstrate	VBD
cord-306424-gf0bglm0	135	11	that	that	IN
cord-306424-gf0bglm0	135	12	EAV	EAV	NNP
cord-306424-gf0bglm0	135	13	and	and	CC
cord-306424-gf0bglm0	135	14	MERS	MERS	NNP
cord-306424-gf0bglm0	135	15	-	-	HYPH
cord-306424-gf0bglm0	135	16	CoV	CoV	NNP
cord-306424-gf0bglm0	135	17	virus	virus	NN
cord-306424-gf0bglm0	135	18	mutants	mutant	NNS
cord-306424-gf0bglm0	135	19	that	that	WDT
cord-306424-gf0bglm0	135	20	lack	lack	VBP
cord-306424-gf0bglm0	135	21	the	the	DT
cord-306424-gf0bglm0	135	22	DUB	dub	NN
cord-306424-gf0bglm0	135	23	activity	activity	NN
cord-306424-gf0bglm0	135	24	of	of	IN
cord-306424-gf0bglm0	135	25	their	-PRON-	PRP$
cord-306424-gf0bglm0	135	26	PLPs	plp	NNS
cord-306424-gf0bglm0	135	27	while	while	IN
cord-306424-gf0bglm0	135	28	retaining	retain	VBG
cord-306424-gf0bglm0	135	29	polyprotein	polyprotein	JJ
cord-306424-gf0bglm0	135	30	cleavage	cleavage	NN
cord-306424-gf0bglm0	135	31	functions	function	NNS
cord-306424-gf0bglm0	135	32	suppress	suppress	VBP
cord-306424-gf0bglm0	135	33	IFN	IFN	NNP
cord-306424-gf0bglm0	135	34	production	production	NN
cord-306424-gf0bglm0	135	35	less	less	RBR
cord-306424-gf0bglm0	135	36	efficiently	efficiently	RB
cord-306424-gf0bglm0	135	37	during	during	IN
cord-306424-gf0bglm0	135	38	infection	infection	NN
cord-306424-gf0bglm0	135	39	(	(	-LRB-
cord-306424-gf0bglm0	135	40	[	[	-LRB-
cord-306424-gf0bglm0	135	41	89	89	CD
cord-306424-gf0bglm0	135	42	,	,	,
cord-306424-gf0bglm0	135	43	90	90	CD
cord-306424-gf0bglm0	135	44	]	]	-RRB-
cord-306424-gf0bglm0	135	45	and	and	CC
cord-306424-gf0bglm0	135	46	our	-PRON-	PRP$
cord-306424-gf0bglm0	135	47	unpublished	unpublished	JJ
cord-306424-gf0bglm0	135	48	data	datum	NNS
cord-306424-gf0bglm0	135	49	)	)	-RRB-
cord-306424-gf0bglm0	135	50	.	.	.
cord-306424-gf0bglm0	136	1	Furthermore	furthermore	RB
cord-306424-gf0bglm0	136	2	,	,	,
cord-306424-gf0bglm0	136	3	viral	viral	JJ
cord-306424-gf0bglm0	136	4	proteins	protein	NNS
cord-306424-gf0bglm0	136	5	such	such	JJ
cord-306424-gf0bglm0	136	6	as	as	IN
cord-306424-gf0bglm0	136	7	DENV	DENV	NNP
cord-306424-gf0bglm0	136	8	NS2B/3	NS2B/3	NNP
cord-306424-gf0bglm0	136	9	and	and	CC
cord-306424-gf0bglm0	136	10	the	the	DT
cord-306424-gf0bglm0	136	11	SARS	SARS	NNP
cord-306424-gf0bglm0	136	12	-	-	HYPH
cord-306424-gf0bglm0	136	13	CoV	CoV	NNP
cord-306424-gf0bglm0	136	14	membrane	membrane	NN
cord-306424-gf0bglm0	136	15	glycoprotein	glycoprotein	NN
cord-306424-gf0bglm0	136	16	interfere	interfere	VBP
cord-306424-gf0bglm0	136	17	with	with	IN
cord-306424-gf0bglm0	136	18	complex	complex	JJ
cord-306424-gf0bglm0	136	19	formation	formation	NN
cord-306424-gf0bglm0	136	20	of	of	IN
cord-306424-gf0bglm0	136	21	IKKe	IKKe	NNP
cord-306424-gf0bglm0	136	22	/	/	SYM
cord-306424-gf0bglm0	136	23	TBK1	TBK1	NNP
cord-306424-gf0bglm0	136	24	and	and	CC
cord-306424-gf0bglm0	136	25	IKKa/	IKKa/	NNP
cord-306424-gf0bglm0	137	1	IKKb/	ikkb/	PRP
cord-306424-gf0bglm0	137	2	IKKg	IKKg	NNS
cord-306424-gf0bglm0	137	3	or	or	CC
cord-306424-gf0bglm0	137	4	downstream	downstream	JJ
cord-306424-gf0bglm0	137	5	transcription	transcription	NN
cord-306424-gf0bglm0	137	6	factors	factor	NNS
cord-306424-gf0bglm0	137	7	,	,	,
cord-306424-gf0bglm0	137	8	thereby	thereby	RB
cord-306424-gf0bglm0	137	9	effectively	effectively	RB
cord-306424-gf0bglm0	137	10	inhibiting	inhibit	VBG
cord-306424-gf0bglm0	137	11	both	both	CC
cord-306424-gf0bglm0	137	12	RLR	RLR	NNP
cord-306424-gf0bglm0	137	13	and	and	CC
cord-306424-gf0bglm0	137	14	TLR	TLR	NNP
cord-306424-gf0bglm0	137	15	signaling	signal	VBG
cord-306424-gf0bglm0	137	16	[	[	-LRB-
cord-306424-gf0bglm0	137	17	91	91	CD
cord-306424-gf0bglm0	137	18	,	,	,
cord-306424-gf0bglm0	137	19	92	92	CD
cord-306424-gf0bglm0	137	20	]	]	-RRB-
cord-306424-gf0bglm0	137	21	.	.	.
cord-306424-gf0bglm0	138	1	Interestingly	interestingly	RB
cord-306424-gf0bglm0	138	2	,	,	,
cord-306424-gf0bglm0	138	3	accessory	accessory	NN
cord-306424-gf0bglm0	138	4	proteins	protein	NNS
cord-306424-gf0bglm0	138	5	encoded	encode	VBN
cord-306424-gf0bglm0	138	6	by	by	IN
cord-306424-gf0bglm0	138	7	open	open	JJ
cord-306424-gf0bglm0	138	8	reading	reading	NN
cord-306424-gf0bglm0	138	9	frames	frame	NNS
cord-306424-gf0bglm0	138	10	of	of	IN
cord-306424-gf0bglm0	138	11	CoVs	CoVs	NNP
cord-306424-gf0bglm0	138	12	have	have	VBP
cord-306424-gf0bglm0	138	13	been	be	VBN
cord-306424-gf0bglm0	138	14	shown	show	VBN
cord-306424-gf0bglm0	138	15	to	to	TO
cord-306424-gf0bglm0	138	16	be	be	VB
cord-306424-gf0bglm0	138	17	involved	involve	VBN
cord-306424-gf0bglm0	138	18	in	in	IN
cord-306424-gf0bglm0	138	19	inhibition	inhibition	NN
cord-306424-gf0bglm0	138	20	of	of	IN
cord-306424-gf0bglm0	138	21	IRF3	IRF3	NNP
cord-306424-gf0bglm0	138	22	,	,	,
cord-306424-gf0bglm0	138	23	IRF7	IRF7	NNP
cord-306424-gf0bglm0	138	24	,	,	,
cord-306424-gf0bglm0	138	25	and	and	CC
cord-306424-gf0bglm0	138	26	NF	NF	NNP
cord-306424-gf0bglm0	138	27	-	-	HYPH
cord-306424-gf0bglm0	138	28	kB	kB	NNP
cord-306424-gf0bglm0	138	29	by	by	IN
cord-306424-gf0bglm0	138	30	undefined	undefined	JJ
cord-306424-gf0bglm0	138	31	mechanisms	mechanism	NNS
cord-306424-gf0bglm0	138	32	[	[	-LRB-
cord-306424-gf0bglm0	138	33	93	93	CD
cord-306424-gf0bglm0	138	34	,	,	,
cord-306424-gf0bglm0	138	35	94	94	CD
cord-306424-gf0bglm0	138	36	]	]	-RRB-
cord-306424-gf0bglm0	138	37	.	.	.
cord-306424-gf0bglm0	139	1	In	in	IN
cord-306424-gf0bglm0	139	2	addition	addition	NN
cord-306424-gf0bglm0	139	3	,	,	,
cord-306424-gf0bglm0	139	4	several	several	JJ
cord-306424-gf0bglm0	139	5	methods	method	NNS
cord-306424-gf0bglm0	139	6	are	be	VBP
cord-306424-gf0bglm0	139	7	employed	employ	VBN
cord-306424-gf0bglm0	139	8	by	by	IN
cord-306424-gf0bglm0	139	9	+	+	SYM
cord-306424-gf0bglm0	139	10	RNA	RNA	NNP
cord-306424-gf0bglm0	139	11	viruses	virus	NNS
cord-306424-gf0bglm0	139	12	to	to	TO
cord-306424-gf0bglm0	139	13	interfere	interfere	VB
cord-306424-gf0bglm0	139	14	with	with	IN
cord-306424-gf0bglm0	139	15	JAK	JAK	NNP
cord-306424-gf0bglm0	139	16	/	/	SYM
cord-306424-gf0bglm0	139	17	STAT	stat	NN
cord-306424-gf0bglm0	139	18	signaling	signal	VBG
cord-306424-gf0bglm0	139	19	.	.	.
cord-306424-gf0bglm0	140	1	For	for	IN
cord-306424-gf0bglm0	140	2	instance	instance	NN
cord-306424-gf0bglm0	140	3	,	,	,
cord-306424-gf0bglm0	140	4	JEV	JEV	NNP
cord-306424-gf0bglm0	140	5	NS5	NS5	NNP
cord-306424-gf0bglm0	140	6	and	and	CC
cord-306424-gf0bglm0	140	7	WNV	WNV	NNP
cord-306424-gf0bglm0	140	8	NS4	NS4	NNP
cord-306424-gf0bglm0	140	9	B	B	NNP
cord-306424-gf0bglm0	140	10	inhibit	inhibit	VB
cord-306424-gf0bglm0	141	1	phosphorylation	phosphorylation	NN
cord-306424-gf0bglm0	141	2	and	and	CC
cord-306424-gf0bglm0	141	3	activation	activation	NN
cord-306424-gf0bglm0	141	4	of	of	IN
cord-306424-gf0bglm0	141	5	JAK1	JAK1	NNP
cord-306424-gf0bglm0	141	6	,	,	,
cord-306424-gf0bglm0	141	7	and	and	CC
cord-306424-gf0bglm0	141	8	suppressors	suppressor	NNS
cord-306424-gf0bglm0	141	9	of	of	IN
cord-306424-gf0bglm0	141	10	JAK1	JAK1	NNP
cord-306424-gf0bglm0	141	11	are	be	VBP
cord-306424-gf0bglm0	141	12	induced	induce	VBN
cord-306424-gf0bglm0	141	13	by	by	IN
cord-306424-gf0bglm0	141	14	viruses	virus	NNS
cord-306424-gf0bglm0	141	15	such	such	JJ
cord-306424-gf0bglm0	141	16	as	as	IN
cord-306424-gf0bglm0	141	17	WNV	WNV	NNP
cord-306424-gf0bglm0	141	18	,	,	,
cord-306424-gf0bglm0	141	19	JEV	JEV	NNP
cord-306424-gf0bglm0	141	20	,	,	,
cord-306424-gf0bglm0	141	21	and	and	CC
cord-306424-gf0bglm0	141	22	chikungunya	chikungunya	NN
cord-306424-gf0bglm0	141	23	virus	virus	NN
cord-306424-gf0bglm0	141	24	[	[	-LRB-
cord-306424-gf0bglm0	141	25	95	95	CD
cord-306424-gf0bglm0	141	26	]	]	-RRB-
cord-306424-gf0bglm0	142	1	[	[	-LRB-
cord-306424-gf0bglm0	142	2	96	96	CD
cord-306424-gf0bglm0	142	3	]	]	-RRB-
cord-306424-gf0bglm0	142	4	[	[	-LRB-
cord-306424-gf0bglm0	142	5	97	97	CD
cord-306424-gf0bglm0	142	6	]	]	-RRB-
cord-306424-gf0bglm0	142	7	[	[	-LRB-
cord-306424-gf0bglm0	142	8	98	98	CD
cord-306424-gf0bglm0	142	9	]	]	-RRB-
cord-306424-gf0bglm0	142	10	[	[	-LRB-
cord-306424-gf0bglm0	142	11	99	99	CD
cord-306424-gf0bglm0	142	12	]	]	-RRB-
cord-306424-gf0bglm0	142	13	.	.	.
cord-306424-gf0bglm0	143	1	However	however	RB
cord-306424-gf0bglm0	143	2	,	,	,
cord-306424-gf0bglm0	143	3	STAT1	stat1	NN
cord-306424-gf0bglm0	143	4	and	and	CC
cord-306424-gf0bglm0	143	5	STAT2	STAT2	NNS
cord-306424-gf0bglm0	143	6	are	be	VBP
cord-306424-gf0bglm0	143	7	most	most	RBS
cord-306424-gf0bglm0	143	8	heavily	heavily	RB
cord-306424-gf0bglm0	143	9	targeted	target	VBN
cord-306424-gf0bglm0	143	10	.	.	.
cord-306424-gf0bglm0	144	1	JEV	JEV	NNP
cord-306424-gf0bglm0	144	2	NS5	NS5	NNP
cord-306424-gf0bglm0	144	3	,	,	,
cord-306424-gf0bglm0	144	4	WNV	WNV	NNP
cord-306424-gf0bglm0	144	5	and	and	CC
cord-306424-gf0bglm0	144	6	DENV	DENV	NNP
cord-306424-gf0bglm0	144	7	NS4B	NS4B	NNP
cord-306424-gf0bglm0	144	8	,	,	,
cord-306424-gf0bglm0	144	9	and	and	CC
cord-306424-gf0bglm0	144	10	JEV	JEV	NNP
cord-306424-gf0bglm0	144	11	NS4A	NS4A	NNP
cord-306424-gf0bglm0	144	12	have	have	VBP
cord-306424-gf0bglm0	144	13	been	be	VBN
cord-306424-gf0bglm0	144	14	shown	show	VBN
cord-306424-gf0bglm0	144	15	to	to	TO
cord-306424-gf0bglm0	144	16	inhibit	inhibit	VB
cord-306424-gf0bglm0	144	17	STAT	stat	NN
cord-306424-gf0bglm0	144	18	activation	activation	NN
cord-306424-gf0bglm0	144	19	.	.	.
cord-306424-gf0bglm0	145	1	In	in	IN
cord-306424-gf0bglm0	145	2	addition	addition	NN
cord-306424-gf0bglm0	145	3	,	,	,
cord-306424-gf0bglm0	145	4	DENV	DENV	NNP
cord-306424-gf0bglm0	145	5	NS5	NS5	NNP
cord-306424-gf0bglm0	145	6	promotes	promote	VBZ
cord-306424-gf0bglm0	145	7	proteasomal	proteasomal	JJ
cord-306424-gf0bglm0	145	8	degradation	degradation	NN
cord-306424-gf0bglm0	145	9	of	of	IN
cord-306424-gf0bglm0	145	10	STAT2	STAT2	NNS
cord-306424-gf0bglm0	145	11	.	.	.
cord-306424-gf0bglm0	146	1	Interestingly	interestingly	RB
cord-306424-gf0bglm0	146	2	,	,	,
cord-306424-gf0bglm0	146	3	SARS	SARS	NNP
cord-306424-gf0bglm0	146	4	-	-	HYPH
cord-306424-gf0bglm0	146	5	CoV	CoV	NNP
cord-306424-gf0bglm0	146	6	inhibits	inhibit	VBZ
cord-306424-gf0bglm0	146	7	STAT1	stat1	NN
cord-306424-gf0bglm0	146	8	signaling	signal	VBG
cord-306424-gf0bglm0	146	9	in	in	IN
cord-306424-gf0bglm0	146	10	three	three	CD
cord-306424-gf0bglm0	146	11	different	different	JJ
cord-306424-gf0bglm0	146	12	ways	way	NNS
cord-306424-gf0bglm0	146	13	.	.	.
cord-306424-gf0bglm0	147	1	Firstly	firstly	RB
cord-306424-gf0bglm0	147	2	,	,	,
cord-306424-gf0bglm0	147	3	SARS	SARS	NNP
cord-306424-gf0bglm0	147	4	-	-	HYPH
cord-306424-gf0bglm0	147	5	CoV	CoV	NNP
cord-306424-gf0bglm0	147	6	nsp1	nsp1	NNS
cord-306424-gf0bglm0	147	7	binds	bind	VBZ
cord-306424-gf0bglm0	147	8	STAT1	stat1	XX
cord-306424-gf0bglm0	147	9	to	to	TO
cord-306424-gf0bglm0	147	10	inhibit	inhibit	VB
cord-306424-gf0bglm0	147	11	its	-PRON-	PRP$
cord-306424-gf0bglm0	147	12	phosphorylation	phosphorylation	NN
cord-306424-gf0bglm0	147	13	[	[	-LRB-
cord-306424-gf0bglm0	147	14	100	100	CD
cord-306424-gf0bglm0	147	15	]	]	-RRB-
cord-306424-gf0bglm0	147	16	.	.	.
cord-306424-gf0bglm0	148	1	Secondly	secondly	RB
cord-306424-gf0bglm0	148	2	,	,	,
cord-306424-gf0bglm0	148	3	the	the	DT
cord-306424-gf0bglm0	148	4	accessory	accessory	NN
cord-306424-gf0bglm0	148	5	protein	protein	NN
cord-306424-gf0bglm0	148	6	encoded	encode	VBN
cord-306424-gf0bglm0	148	7	by	by	IN
cord-306424-gf0bglm0	148	8	SARS	SARS	NNP
cord-306424-gf0bglm0	148	9	-	-	HYPH
cord-306424-gf0bglm0	148	10	CoV	CoV	NNP
cord-306424-gf0bglm0	148	11	open	open	JJ
cord-306424-gf0bglm0	148	12	reading	reading	NN
cord-306424-gf0bglm0	148	13	frame	frame	NN
cord-306424-gf0bglm0	148	14	6	6	CD
cord-306424-gf0bglm0	148	15	prevents	prevent	VBZ
cord-306424-gf0bglm0	148	16	nuclear	nuclear	JJ
cord-306424-gf0bglm0	148	17	transport	transport	NN
cord-306424-gf0bglm0	148	18	of	of	IN
cord-306424-gf0bglm0	148	19	STAT1	stat1	NN
cord-306424-gf0bglm0	148	20	[	[	-LRB-
cord-306424-gf0bglm0	148	21	93	93	CD
cord-306424-gf0bglm0	148	22	,	,	,
cord-306424-gf0bglm0	148	23	101	101	CD
cord-306424-gf0bglm0	148	24	]	]	-RRB-
cord-306424-gf0bglm0	148	25	.	.	.
cord-306424-gf0bglm0	149	1	Thirdly	thirdly	RB
cord-306424-gf0bglm0	149	2	,	,	,
cord-306424-gf0bglm0	149	3	SARS	SARS	NNP
cord-306424-gf0bglm0	149	4	-	-	HYPH
cord-306424-gf0bglm0	149	5	CoV	cov	NN
cord-306424-gf0bglm0	149	6	PLP	PLP	NNP
cord-306424-gf0bglm0	149	7	induces	induce	VBZ
cord-306424-gf0bglm0	149	8	expression	expression	NN
cord-306424-gf0bglm0	149	9	of	of	IN
cord-306424-gf0bglm0	149	10	E3	e3	NN
cord-306424-gf0bglm0	149	11	ubiquitin	ubiquitin	NN
cord-306424-gf0bglm0	149	12	ligase	ligase	NN
cord-306424-gf0bglm0	149	13	E2	E2	NNP
cord-306424-gf0bglm0	149	14	-	-	HYPH
cord-306424-gf0bglm0	149	15	25k	25k	NNP
cord-306424-gf0bglm0	149	16	,	,	,
cord-306424-gf0bglm0	149	17	which	which	WDT
cord-306424-gf0bglm0	149	18	promotes	promote	VBZ
cord-306424-gf0bglm0	149	19	proteasomal	proteasomal	JJ
cord-306424-gf0bglm0	149	20	degradation	degradation	NN
cord-306424-gf0bglm0	149	21	of	of	IN
cord-306424-gf0bglm0	149	22	extracellular	extracellular	JJ
cord-306424-gf0bglm0	149	23	signal	signal	NN
cord-306424-gf0bglm0	149	24	-	-	HYPH
cord-306424-gf0bglm0	149	25	regulated	regulate	VBN
cord-306424-gf0bglm0	149	26	kinase	kinase	NN
cord-306424-gf0bglm0	149	27	1	1	CD
cord-306424-gf0bglm0	149	28	,	,	,
cord-306424-gf0bglm0	149	29	a	a	DT
cord-306424-gf0bglm0	149	30	protein	protein	NN
cord-306424-gf0bglm0	149	31	responsible	responsible	JJ
cord-306424-gf0bglm0	149	32	for	for	IN
cord-306424-gf0bglm0	149	33	activation	activation	NN
cord-306424-gf0bglm0	149	34	of	of	IN
cord-306424-gf0bglm0	149	35	STAT1	stat1	NN
cord-306424-gf0bglm0	149	36	[	[	-LRB-
cord-306424-gf0bglm0	149	37	102	102	CD
cord-306424-gf0bglm0	149	38	]	]	-RRB-
cord-306424-gf0bglm0	149	39	.	.	.
cord-306424-gf0bglm0	150	1	To	to	IN
cord-306424-gf0bglm0	150	2	our	-PRON-	PRP$
cord-306424-gf0bglm0	150	3	knowledge	knowledge	NN
cord-306424-gf0bglm0	150	4	,	,	,
cord-306424-gf0bglm0	150	5	no	no	DT
cord-306424-gf0bglm0	150	6	studies	study	NNS
cord-306424-gf0bglm0	150	7	have	have	VBP
cord-306424-gf0bglm0	150	8	been	be	VBN
cord-306424-gf0bglm0	150	9	published	publish	VBN
cord-306424-gf0bglm0	150	10	(	(	-LRB-
cord-306424-gf0bglm0	150	11	yet	yet	RB
cord-306424-gf0bglm0	150	12	)	)	-RRB-
cord-306424-gf0bglm0	150	13	about	about	IN
cord-306424-gf0bglm0	150	14	specific	specific	JJ
cord-306424-gf0bglm0	150	15	interference	interference	NN
cord-306424-gf0bglm0	150	16	of	of	IN
cord-306424-gf0bglm0	150	17	+	+	``
cord-306424-gf0bglm0	150	18	RNA	RNA	NNP
cord-306424-gf0bglm0	150	19	viruses	virus	NNS
cord-306424-gf0bglm0	150	20	with	with	IN
cord-306424-gf0bglm0	150	21	IFN	IFN	NNP
cord-306424-gf0bglm0	150	22	-	-	HYPH
cord-306424-gf0bglm0	150	23	II	II	NNP
cord-306424-gf0bglm0	150	24	production	production	NN
cord-306424-gf0bglm0	150	25	.	.	.
cord-306424-gf0bglm0	151	1	Interference	interference	NN
cord-306424-gf0bglm0	151	2	of	of	IN
cord-306424-gf0bglm0	151	3	+	+	``
cord-306424-gf0bglm0	151	4	RNA	RNA	NNP
cord-306424-gf0bglm0	151	5	viruses	virus	NNS
cord-306424-gf0bglm0	151	6	with	with	IN
cord-306424-gf0bglm0	151	7	antiviral	antiviral	JJ
cord-306424-gf0bglm0	151	8	signaling	signaling	NN
cord-306424-gf0bglm0	151	9	also	also	RB
cord-306424-gf0bglm0	151	10	has	have	VBZ
cord-306424-gf0bglm0	151	11	consequences	consequence	NNS
cord-306424-gf0bglm0	151	12	for	for	IN
cord-306424-gf0bglm0	151	13	the	the	DT
cord-306424-gf0bglm0	151	14	spatial	spatial	JJ
cord-306424-gf0bglm0	151	15	organization	organization	NN
cord-306424-gf0bglm0	151	16	of	of	IN
cord-306424-gf0bglm0	151	17	the	the	DT
cord-306424-gf0bglm0	151	18	antiviral	antiviral	JJ
cord-306424-gf0bglm0	151	19	innate	innate	JJ
cord-306424-gf0bglm0	151	20	immune	immune	JJ
cord-306424-gf0bglm0	151	21	system	system	NN
cord-306424-gf0bglm0	151	22	.	.	.
cord-306424-gf0bglm0	152	1	For	for	IN
cord-306424-gf0bglm0	152	2	instance	instance	NN
cord-306424-gf0bglm0	152	3	,	,	,
cord-306424-gf0bglm0	152	4	since	since	IN
cord-306424-gf0bglm0	152	5	SGs	SGs	NNP
cord-306424-gf0bglm0	152	6	suggestively	suggestively	RB
cord-306424-gf0bglm0	152	7	have	have	VBP
cord-306424-gf0bglm0	152	8	an	an	DT
cord-306424-gf0bglm0	152	9	antiviral	antiviral	JJ
cord-306424-gf0bglm0	152	10	role	role	NN
cord-306424-gf0bglm0	152	11	,	,	,
cord-306424-gf0bglm0	152	12	interfering	interfere	VBG
cord-306424-gf0bglm0	152	13	with	with	IN
cord-306424-gf0bglm0	152	14	SG	SG	NNP
cord-306424-gf0bglm0	152	15	formation	formation	NN
cord-306424-gf0bglm0	152	16	might	may	MD
cord-306424-gf0bglm0	152	17	constitute	constitute	VB
cord-306424-gf0bglm0	152	18	an	an	DT
cord-306424-gf0bglm0	152	19	opportunity	opportunity	NN
cord-306424-gf0bglm0	152	20	for	for	IN
cord-306424-gf0bglm0	152	21	viruses	virus	NNS
cord-306424-gf0bglm0	152	22	to	to	TO
cord-306424-gf0bglm0	152	23	hamper	hamper	VB
cord-306424-gf0bglm0	152	24	the	the	DT
cord-306424-gf0bglm0	152	25	innate	innate	JJ
cord-306424-gf0bglm0	152	26	immune	immune	JJ
cord-306424-gf0bglm0	152	27	response	response	NN
cord-306424-gf0bglm0	152	28	.	.	.
cord-306424-gf0bglm0	153	1	Indeed	indeed	RB
cord-306424-gf0bglm0	153	2	,	,	,
cord-306424-gf0bglm0	153	3	various	various	JJ
cord-306424-gf0bglm0	153	4	proteins	protein	NNS
cord-306424-gf0bglm0	153	5	of	of	IN
cord-306424-gf0bglm0	153	6	poliovirus	poliovirus	NN
cord-306424-gf0bglm0	153	7	,	,	,
cord-306424-gf0bglm0	153	8	coxsackievirus	coxsackievirus	NNP
cord-306424-gf0bglm0	153	9	,	,	,
cord-306424-gf0bglm0	153	10	encephalomyocarditis	encephalomyocarditis	NNP
cord-306424-gf0bglm0	153	11	virus	virus	NN
cord-306424-gf0bglm0	153	12	,	,	,
cord-306424-gf0bglm0	153	13	DENV	DENV	NNP
cord-306424-gf0bglm0	153	14	,	,	,
cord-306424-gf0bglm0	153	15	WNV	WNV	NNP
cord-306424-gf0bglm0	153	16	,	,	,
cord-306424-gf0bglm0	153	17	MERS	MERS	NNP
cord-306424-gf0bglm0	153	18	-	-	HYPH
cord-306424-gf0bglm0	153	19	CoV	CoV	NNP
cord-306424-gf0bglm0	153	20	,	,	,
cord-306424-gf0bglm0	153	21	chikungunya	chikungunya	NN
cord-306424-gf0bglm0	153	22	virus	virus	NN
cord-306424-gf0bglm0	153	23	,	,	,
cord-306424-gf0bglm0	153	24	and	and	CC
cord-306424-gf0bglm0	153	25	JEV	JEV	NNP
cord-306424-gf0bglm0	153	26	have	have	VBP
cord-306424-gf0bglm0	153	27	been	be	VBN
cord-306424-gf0bglm0	153	28	shown	show	VBN
cord-306424-gf0bglm0	153	29	to	to	TO
cord-306424-gf0bglm0	153	30	prevent	prevent	VB
cord-306424-gf0bglm0	153	31	the	the	DT
cord-306424-gf0bglm0	153	32	formation	formation	NN
cord-306424-gf0bglm0	153	33	of	of	IN
cord-306424-gf0bglm0	153	34	SGs	SGs	NNP
cord-306424-gf0bglm0	153	35	and	and	CC
cord-306424-gf0bglm0	153	36	thereby	thereby	RB
cord-306424-gf0bglm0	153	37	suppress	suppress	VB
cord-306424-gf0bglm0	153	38	IFN	IFN	NNP
cord-306424-gf0bglm0	153	39	production	production	NN
cord-306424-gf0bglm0	153	40	[	[	-LRB-
cord-306424-gf0bglm0	153	41	63	63	CD
cord-306424-gf0bglm0	153	42	,	,	,
cord-306424-gf0bglm0	153	43	66	66	CD
cord-306424-gf0bglm0	153	44	,	,	,
cord-306424-gf0bglm0	153	45	[	[	-LRB-
cord-306424-gf0bglm0	153	46	103	103	CD
cord-306424-gf0bglm0	153	47	]	]	-RRB-
cord-306424-gf0bglm0	153	48	[	[	-LRB-
cord-306424-gf0bglm0	153	49	104	104	CD
cord-306424-gf0bglm0	153	50	]	]	-RRB-
cord-306424-gf0bglm0	153	51	[	[	-LRB-
cord-306424-gf0bglm0	153	52	105	105	CD
cord-306424-gf0bglm0	153	53	]	]	-RRB-
cord-306424-gf0bglm0	153	54	[	[	-LRB-
cord-306424-gf0bglm0	153	55	106	106	CD
cord-306424-gf0bglm0	153	56	]	]	-RRB-
cord-306424-gf0bglm0	154	1	[	[	-LRB-
cord-306424-gf0bglm0	154	2	107	107	CD
cord-306424-gf0bglm0	154	3	]	]	-RRB-
cord-306424-gf0bglm0	155	1	[	[	-LRB-
cord-306424-gf0bglm0	155	2	108	108	CD
cord-306424-gf0bglm0	155	3	]	]	-RRB-
cord-306424-gf0bglm0	155	4	[	[	-LRB-
cord-306424-gf0bglm0	155	5	109	109	CD
cord-306424-gf0bglm0	155	6	]	]	-RRB-
cord-306424-gf0bglm0	155	7	.	.	.
cord-306424-gf0bglm0	156	1	Thus	thus	RB
cord-306424-gf0bglm0	156	2	,	,	,
cord-306424-gf0bglm0	156	3	dysregulation	dysregulation	NN
cord-306424-gf0bglm0	156	4	of	of	IN
cord-306424-gf0bglm0	156	5	SGs	SGs	NNP
cord-306424-gf0bglm0	156	6	seems	seem	VBZ
cord-306424-gf0bglm0	156	7	to	to	TO
cord-306424-gf0bglm0	156	8	be	be	VB
cord-306424-gf0bglm0	156	9	a	a	DT
cord-306424-gf0bglm0	156	10	common	common	JJ
cord-306424-gf0bglm0	156	11	strategy	strategy	NN
cord-306424-gf0bglm0	156	12	for	for	IN
cord-306424-gf0bglm0	156	13	+	+	SYM
cord-306424-gf0bglm0	156	14	RNA	RNA	NNP
cord-306424-gf0bglm0	156	15	viruses	virus	NNS
cord-306424-gf0bglm0	156	16	in	in	IN
cord-306424-gf0bglm0	156	17	order	order	NN
cord-306424-gf0bglm0	156	18	to	to	TO
cord-306424-gf0bglm0	156	19	dampen	dampen	VB
cord-306424-gf0bglm0	156	20	the	the	DT
cord-306424-gf0bglm0	156	21	innate	innate	JJ
cord-306424-gf0bglm0	156	22	antiviral	antiviral	JJ
cord-306424-gf0bglm0	156	23	immune	immune	JJ
cord-306424-gf0bglm0	156	24	response	response	NN
cord-306424-gf0bglm0	156	25	.	.	.
cord-306424-gf0bglm0	157	1	In	in	IN
cord-306424-gf0bglm0	157	2	addition	addition	NN
cord-306424-gf0bglm0	157	3	,	,	,
cord-306424-gf0bglm0	157	4	the	the	DT
cord-306424-gf0bglm0	157	5	finding	finding	NN
cord-306424-gf0bglm0	157	6	that	that	IN
cord-306424-gf0bglm0	157	7	MAMs	mam	NNS
cord-306424-gf0bglm0	157	8	are	be	VBP
cord-306424-gf0bglm0	157	9	involved	involve	VBN
cord-306424-gf0bglm0	157	10	in	in	IN
cord-306424-gf0bglm0	157	11	the	the	DT
cord-306424-gf0bglm0	157	12	RLR	RLR	NNP
cord-306424-gf0bglm0	157	13	-	-	HYPH
cord-306424-gf0bglm0	157	14	mediated	mediate	VBN
cord-306424-gf0bglm0	157	15	antiviral	antiviral	JJ
cord-306424-gf0bglm0	157	16	immune	immune	NN
cord-306424-gf0bglm0	157	17	signaling	signal	VBG
cord-306424-gf0bglm0	157	18	pathway	pathway	NN
cord-306424-gf0bglm0	157	19	shedded	shedde	VBD
cord-306424-gf0bglm0	157	20	new	new	JJ
cord-306424-gf0bglm0	157	21	light	light	NN
cord-306424-gf0bglm0	157	22	on	on	IN
cord-306424-gf0bglm0	157	23	the	the	DT
cord-306424-gf0bglm0	157	24	immunosuppressive	immunosuppressive	JJ
cord-306424-gf0bglm0	157	25	role	role	NN
cord-306424-gf0bglm0	157	26	of	of	IN
cord-306424-gf0bglm0	157	27	viral	viral	JJ
cord-306424-gf0bglm0	157	28	proteases	protease	NNS
cord-306424-gf0bglm0	157	29	.	.	.
cord-306424-gf0bglm0	158	1	By	by	IN
cord-306424-gf0bglm0	158	2	performing	perform	VBG
cord-306424-gf0bglm0	158	3	colocalization	colocalization	NN
cord-306424-gf0bglm0	158	4	analysis	analysis	NN
cord-306424-gf0bglm0	158	5	with	with	IN
cord-306424-gf0bglm0	158	6	a	a	DT
cord-306424-gf0bglm0	158	7	MAM	mam	NN
cord-306424-gf0bglm0	158	8	-	-	HYPH
cord-306424-gf0bglm0	158	9	enriched	enrich	VBN
cord-306424-gf0bglm0	158	10	marker	marker	NN
cord-306424-gf0bglm0	158	11	protein	protein	NN
cord-306424-gf0bglm0	158	12	and	and	CC
cord-306424-gf0bglm0	158	13	cell	cell	NN
cord-306424-gf0bglm0	158	14	fractionation	fractionation	NN
cord-306424-gf0bglm0	158	15	experiments	experiment	NNS
cord-306424-gf0bglm0	158	16	in	in	IN
cord-306424-gf0bglm0	158	17	both	both	CC
cord-306424-gf0bglm0	158	18	uninfected	uninfected	JJ
cord-306424-gf0bglm0	158	19	and	and	CC
cord-306424-gf0bglm0	158	20	HCV	HCV	NNP
cord-306424-gf0bglm0	158	21	-	-	HYPH
cord-306424-gf0bglm0	158	22	infected	infect	VBN
cord-306424-gf0bglm0	158	23	cells	cell	NNS
cord-306424-gf0bglm0	158	24	,	,	,
cord-306424-gf0bglm0	158	25	it	-PRON-	PRP
cord-306424-gf0bglm0	158	26	was	be	VBD
cord-306424-gf0bglm0	158	27	found	find	VBN
cord-306424-gf0bglm0	158	28	that	that	IN
cord-306424-gf0bglm0	158	29	NS3/4A	ns3/4a	PRP
cord-306424-gf0bglm0	158	30	also	also	RB
cord-306424-gf0bglm0	158	31	localizes	localize	VBZ
cord-306424-gf0bglm0	158	32	to	to	IN
cord-306424-gf0bglm0	158	33	MAMs	MAMs	NNP
cord-306424-gf0bglm0	158	34	[	[	-LRB-
cord-306424-gf0bglm0	158	35	58	58	CD
cord-306424-gf0bglm0	158	36	]	]	-RRB-
cord-306424-gf0bglm0	158	37	.	.	.
cord-306424-gf0bglm0	159	1	Intriguingly	intriguingly	RB
cord-306424-gf0bglm0	159	2	,	,	,
cord-306424-gf0bglm0	159	3	despite	despite	IN
cord-306424-gf0bglm0	159	4	the	the	DT
cord-306424-gf0bglm0	159	5	clear	clear	JJ
cord-306424-gf0bglm0	159	6	function	function	NN
cord-306424-gf0bglm0	159	7	for	for	IN
cord-306424-gf0bglm0	159	8	peroxisomal	peroxisomal	JJ
cord-306424-gf0bglm0	159	9	MAVS	MAVS	NNPS
cord-306424-gf0bglm0	159	10	in	in	IN
cord-306424-gf0bglm0	159	11	antiviral	antiviral	JJ
cord-306424-gf0bglm0	159	12	signaling	signaling	NN
cord-306424-gf0bglm0	159	13	,	,	,
cord-306424-gf0bglm0	159	14	cleaved	cleave	VBN
cord-306424-gf0bglm0	159	15	MAVS	MAVS	NNPS
cord-306424-gf0bglm0	159	16	was	be	VBD
cord-306424-gf0bglm0	159	17	found	find	VBN
cord-306424-gf0bglm0	159	18	solely	solely	RB
cord-306424-gf0bglm0	159	19	in	in	IN
cord-306424-gf0bglm0	159	20	MAM	mam	NN
cord-306424-gf0bglm0	159	21	-	-	HYPH
cord-306424-gf0bglm0	159	22	enriched	enrich	VBN
cord-306424-gf0bglm0	159	23	cell	cell	NN
cord-306424-gf0bglm0	159	24	fractions	fraction	NNS
cord-306424-gf0bglm0	159	25	.	.	.
cord-306424-gf0bglm0	160	1	In	in	IN
cord-306424-gf0bglm0	160	2	addition	addition	NN
cord-306424-gf0bglm0	160	3	,	,	,
cord-306424-gf0bglm0	160	4	recent	recent	JJ
cord-306424-gf0bglm0	160	5	findings	finding	NNS
cord-306424-gf0bglm0	160	6	suggest	suggest	VBP
cord-306424-gf0bglm0	160	7	that	that	IN
cord-306424-gf0bglm0	160	8	MAMs	mam	NNS
cord-306424-gf0bglm0	160	9	are	be	VBP
cord-306424-gf0bglm0	160	10	also	also	RB
cord-306424-gf0bglm0	160	11	physically	physically	RB
cord-306424-gf0bglm0	160	12	disrupted	disrupt	VBN
cord-306424-gf0bglm0	160	13	during	during	IN
cord-306424-gf0bglm0	160	14	DENV	DENV	NNP
cord-306424-gf0bglm0	160	15	infection	infection	NN
cord-306424-gf0bglm0	160	16	[	[	-LRB-
cord-306424-gf0bglm0	160	17	110	110	CD
cord-306424-gf0bglm0	160	18	]	]	-RRB-
cord-306424-gf0bglm0	160	19	.	.	.
cord-306424-gf0bglm0	161	1	Thus	thus	RB
cord-306424-gf0bglm0	161	2	,	,	,
cord-306424-gf0bglm0	161	3	these	these	DT
cord-306424-gf0bglm0	161	4	data	datum	NNS
cord-306424-gf0bglm0	161	5	indicate	indicate	VBP
cord-306424-gf0bglm0	161	6	that	that	IN
cord-306424-gf0bglm0	161	7	MAMs	mam	NNS
cord-306424-gf0bglm0	161	8	are	be	VBP
cord-306424-gf0bglm0	161	9	critical	critical	JJ
cord-306424-gf0bglm0	161	10	locations	location	NNS
cord-306424-gf0bglm0	161	11	for	for	IN
cord-306424-gf0bglm0	161	12	antiviral	antiviral	JJ
cord-306424-gf0bglm0	161	13	signaling	signaling	NN
cord-306424-gf0bglm0	161	14	and	and	CC
cord-306424-gf0bglm0	161	15	have	have	VBP
cord-306424-gf0bglm0	161	16	an	an	DT
cord-306424-gf0bglm0	161	17	important	important	JJ
cord-306424-gf0bglm0	161	18	role	role	NN
cord-306424-gf0bglm0	161	19	in	in	IN
cord-306424-gf0bglm0	161	20	expression	expression	NN
cord-306424-gf0bglm0	161	21	of	of	IN
cord-306424-gf0bglm0	161	22	type	type	NN
cord-306424-gf0bglm0	161	23	I	-PRON-	PRP
cord-306424-gf0bglm0	161	24	and	and	CC
cord-306424-gf0bglm0	161	25	III	III	NNP
cord-306424-gf0bglm0	161	26	IFNs	ifn	NNS
cord-306424-gf0bglm0	161	27	.	.	.
cord-306424-gf0bglm0	162	1	Moreover	moreover	RB
cord-306424-gf0bglm0	162	2	,	,	,
cord-306424-gf0bglm0	162	3	increasing	increase	VBG
cord-306424-gf0bglm0	162	4	evidence	evidence	NN
cord-306424-gf0bglm0	162	5	suggests	suggest	VBZ
cord-306424-gf0bglm0	162	6	that	that	IN
cord-306424-gf0bglm0	162	7	at	at	IN
cord-306424-gf0bglm0	162	8	least	least	JJS
cord-306424-gf0bglm0	162	9	some	some	DT
cord-306424-gf0bglm0	162	10	+	+	SYM
cord-306424-gf0bglm0	162	11	RNA	RNA	NNP
cord-306424-gf0bglm0	162	12	viruses	virus	NNS
cord-306424-gf0bglm0	162	13	in	in	IN
cord-306424-gf0bglm0	162	14	fact	fact	NN
cord-306424-gf0bglm0	162	15	occupy	occupy	VB
cord-306424-gf0bglm0	162	16	or	or	CC
cord-306424-gf0bglm0	162	17	hijack	hijack	VB
cord-306424-gf0bglm0	162	18	MAM	mam	NN
cord-306424-gf0bglm0	162	19	-	-	HYPH
cord-306424-gf0bglm0	162	20	membranes	membrane	NNS
cord-306424-gf0bglm0	162	21	during	during	IN
cord-306424-gf0bglm0	162	22	infection	infection	NN
cord-306424-gf0bglm0	162	23	,	,	,
cord-306424-gf0bglm0	162	24	as	as	IN
cord-306424-gf0bglm0	162	25	MAMs	mam	NNS
cord-306424-gf0bglm0	162	26	of	of	IN
cord-306424-gf0bglm0	162	27	HCV	HCV	NNP
cord-306424-gf0bglm0	162	28	-	-	HYPH
cord-306424-gf0bglm0	162	29	infected	infect	VBN
cord-306424-gf0bglm0	162	30	cells	cell	NNS
cord-306424-gf0bglm0	162	31	were	be	VBD
cord-306424-gf0bglm0	162	32	found	find	VBN
cord-306424-gf0bglm0	162	33	to	to	TO
cord-306424-gf0bglm0	162	34	contain	contain	VB
cord-306424-gf0bglm0	162	35	proteins	protein	NNS
cord-306424-gf0bglm0	162	36	involved	involve	VBN
cord-306424-gf0bglm0	162	37	in	in	IN
cord-306424-gf0bglm0	162	38	virus	virus	NN
cord-306424-gf0bglm0	162	39	assembly	assembly	NN
cord-306424-gf0bglm0	162	40	and	and	CC
cord-306424-gf0bglm0	162	41	fully	fully	RB
cord-306424-gf0bglm0	162	42	assembled	assemble	VBN
cord-306424-gf0bglm0	162	43	virions	virion	NNS
cord-306424-gf0bglm0	162	44	[	[	-LRB-
cord-306424-gf0bglm0	162	45	111	111	CD
cord-306424-gf0bglm0	162	46	]	]	-RRB-
cord-306424-gf0bglm0	162	47	.	.	.
cord-306424-gf0bglm0	163	1	It	-PRON-	PRP
cord-306424-gf0bglm0	163	2	remains	remain	VBZ
cord-306424-gf0bglm0	163	3	to	to	TO
cord-306424-gf0bglm0	163	4	be	be	VB
cord-306424-gf0bglm0	163	5	investigated	investigate	VBN
cord-306424-gf0bglm0	163	6	whether	whether	IN
cord-306424-gf0bglm0	163	7	MAMs	mam	NNS
cord-306424-gf0bglm0	163	8	also	also	RB
cord-306424-gf0bglm0	163	9	serve	serve	VBP
cord-306424-gf0bglm0	163	10	as	as	IN
cord-306424-gf0bglm0	163	11	platforms	platform	NNS
cord-306424-gf0bglm0	163	12	for	for	IN
cord-306424-gf0bglm0	163	13	viral	viral	JJ
cord-306424-gf0bglm0	163	14	assembly	assembly	NN
cord-306424-gf0bglm0	163	15	of	of	IN
cord-306424-gf0bglm0	163	16	other	other	JJ
cord-306424-gf0bglm0	163	17	+	+	CC
cord-306424-gf0bglm0	163	18	RNA	RNA	NNP
cord-306424-gf0bglm0	163	19	viruses	virus	NNS
cord-306424-gf0bglm0	163	20	.	.	.
cord-306424-gf0bglm0	164	1	In	in	IN
cord-306424-gf0bglm0	164	2	addition	addition	NN
cord-306424-gf0bglm0	164	3	,	,	,
cord-306424-gf0bglm0	164	4	MAM	MAM	NNP
cord-306424-gf0bglm0	164	5	disruption	disruption	NN
cord-306424-gf0bglm0	164	6	as	as	IN
cord-306424-gf0bglm0	164	7	a	a	DT
cord-306424-gf0bglm0	164	8	consequence	consequence	NN
cord-306424-gf0bglm0	164	9	of	of	IN
cord-306424-gf0bglm0	164	10	DENV	DENV	NNP
cord-306424-gf0bglm0	164	11	infection	infection	NN
cord-306424-gf0bglm0	164	12	was	be	VBD
cord-306424-gf0bglm0	164	13	followed	follow	VBN
cord-306424-gf0bglm0	164	14	by	by	IN
cord-306424-gf0bglm0	164	15	the	the	DT
cord-306424-gf0bglm0	164	16	formation	formation	NN
cord-306424-gf0bglm0	164	17	of	of	IN
cord-306424-gf0bglm0	164	18	convoluted	convoluted	JJ
cord-306424-gf0bglm0	164	19	membranes	membrane	NNS
cord-306424-gf0bglm0	164	20	at	at	IN
cord-306424-gf0bglm0	164	21	the	the	DT
cord-306424-gf0bglm0	164	22	same	same	JJ
cord-306424-gf0bglm0	164	23	location	location	NN
cord-306424-gf0bglm0	164	24	,	,	,
cord-306424-gf0bglm0	164	25	which	which	WDT
cord-306424-gf0bglm0	164	26	supported	support	VBD
cord-306424-gf0bglm0	164	27	DENV	DENV	NNP
cord-306424-gf0bglm0	164	28	replication	replication	NN
cord-306424-gf0bglm0	164	29	[	[	-LRB-
cord-306424-gf0bglm0	164	30	110	110	CD
cord-306424-gf0bglm0	164	31	]	]	-RRB-
cord-306424-gf0bglm0	164	32	.	.	.
cord-306424-gf0bglm0	165	1	Moreover	moreover	RB
cord-306424-gf0bglm0	165	2	,	,	,
cord-306424-gf0bglm0	165	3	promoting	promote	VBG
cord-306424-gf0bglm0	165	4	the	the	DT
cord-306424-gf0bglm0	165	5	formation	formation	NN
cord-306424-gf0bglm0	165	6	of	of	IN
cord-306424-gf0bglm0	165	7	convoluted	convoluted	JJ
cord-306424-gf0bglm0	165	8	membranes	membrane	NNS
cord-306424-gf0bglm0	165	9	further	further	RB
cord-306424-gf0bglm0	165	10	repressed	repress	VBD
cord-306424-gf0bglm0	165	11	the	the	DT
cord-306424-gf0bglm0	165	12	IFN	IFN	NNP
cord-306424-gf0bglm0	165	13	response	response	NN
cord-306424-gf0bglm0	165	14	,	,	,
cord-306424-gf0bglm0	165	15	underscoring	underscore	VBG
cord-306424-gf0bglm0	165	16	the	the	DT
cord-306424-gf0bglm0	165	17	importance	importance	NN
cord-306424-gf0bglm0	165	18	of	of	IN
cord-306424-gf0bglm0	165	19	MAM	MAM	NNP
cord-306424-gf0bglm0	165	20	disruption	disruption	NN
cord-306424-gf0bglm0	165	21	in	in	IN
cord-306424-gf0bglm0	165	22	both	both	CC
cord-306424-gf0bglm0	165	23	the	the	DT
cord-306424-gf0bglm0	165	24	replication	replication	NN
cord-306424-gf0bglm0	165	25	and	and	CC
cord-306424-gf0bglm0	165	26	immune	immune	JJ
cord-306424-gf0bglm0	165	27	evasion	evasion	NN
cord-306424-gf0bglm0	165	28	of	of	IN
cord-306424-gf0bglm0	165	29	+	+	SYM
cord-306424-gf0bglm0	165	30	RNA	RNA	NNP
cord-306424-gf0bglm0	165	31	viruses	virus	NNS
cord-306424-gf0bglm0	165	32	[	[	-LRB-
cord-306424-gf0bglm0	165	33	110	110	CD
cord-306424-gf0bglm0	165	34	]	]	-RRB-
cord-306424-gf0bglm0	165	35	.	.	.
cord-306424-gf0bglm0	166	1	Taken	take	VBN
cord-306424-gf0bglm0	166	2	together	together	RB
cord-306424-gf0bglm0	166	3	,	,	,
cord-306424-gf0bglm0	166	4	these	these	DT
cord-306424-gf0bglm0	166	5	studies	study	NNS
cord-306424-gf0bglm0	166	6	underscore	underscore	VBP
cord-306424-gf0bglm0	166	7	the	the	DT
cord-306424-gf0bglm0	166	8	importance	importance	NN
cord-306424-gf0bglm0	166	9	of	of	IN
cord-306424-gf0bglm0	166	10	MAMs	mam	NNS
cord-306424-gf0bglm0	166	11	as	as	IN
cord-306424-gf0bglm0	166	12	key	key	JJ
cord-306424-gf0bglm0	166	13	antiviral	antiviral	JJ
cord-306424-gf0bglm0	166	14	signaling	signal	VBG
cord-306424-gf0bglm0	166	15	platforms	platform	NNS
cord-306424-gf0bglm0	166	16	,	,	,
cord-306424-gf0bglm0	166	17	and	and	CC
cord-306424-gf0bglm0	166	18	disruption	disruption	NN
cord-306424-gf0bglm0	166	19	of	of	IN
cord-306424-gf0bglm0	166	20	MAMs	MAMs	NNP
cord-306424-gf0bglm0	166	21	constitutes	constitute	VBZ
cord-306424-gf0bglm0	166	22	an	an	DT
cord-306424-gf0bglm0	166	23	effective	effective	JJ
cord-306424-gf0bglm0	166	24	immune	immune	JJ
cord-306424-gf0bglm0	166	25	evasion	evasion	NN
cord-306424-gf0bglm0	166	26	strategy	strategy	NN
cord-306424-gf0bglm0	166	27	for	for	IN
cord-306424-gf0bglm0	166	28	+	+	SYM
cord-306424-gf0bglm0	166	29	RNA	RNA	NNP
cord-306424-gf0bglm0	166	30	viruses	virus	NNS
cord-306424-gf0bglm0	166	31	.	.	.
cord-306424-gf0bglm0	167	1	In	in	IN
cord-306424-gf0bglm0	167	2	conclusion	conclusion	NN
cord-306424-gf0bglm0	167	3	,	,	,
cord-306424-gf0bglm0	167	4	+	+	CC
cord-306424-gf0bglm0	167	5	RNA	RNA	NNP
cord-306424-gf0bglm0	167	6	viruses	virus	NNS
cord-306424-gf0bglm0	167	7	developed	develop	VBD
cord-306424-gf0bglm0	167	8	divergent	divergent	JJ
cord-306424-gf0bglm0	167	9	methods	method	NNS
cord-306424-gf0bglm0	167	10	to	to	TO
cord-306424-gf0bglm0	167	11	delay	delay	VB
cord-306424-gf0bglm0	167	12	antiviral	antiviral	JJ
cord-306424-gf0bglm0	167	13	innate	innate	JJ
cord-306424-gf0bglm0	167	14	immune	immune	NN
cord-306424-gf0bglm0	167	15	signaling	signal	VBG
cord-306424-gf0bglm0	167	16	at	at	IN
cord-306424-gf0bglm0	167	17	multiple	multiple	JJ
cord-306424-gf0bglm0	167	18	levels	level	NNS
cord-306424-gf0bglm0	167	19	.	.	.
cord-306424-gf0bglm0	168	1	In	in	IN
cord-306424-gf0bglm0	168	2	addition	addition	NN
cord-306424-gf0bglm0	168	3	,	,	,
cord-306424-gf0bglm0	168	4	interference	interference	NN
cord-306424-gf0bglm0	168	5	of	of	IN
cord-306424-gf0bglm0	168	6	+	+	``
cord-306424-gf0bglm0	168	7	RNA	RNA	NNP
cord-306424-gf0bglm0	168	8	viruses	virus	NNS
cord-306424-gf0bglm0	168	9	with	with	IN
cord-306424-gf0bglm0	168	10	antiviral	antiviral	JJ
cord-306424-gf0bglm0	168	11	signaling	signaling	NN
cord-306424-gf0bglm0	168	12	leads	lead	NNS
cord-306424-gf0bglm0	168	13	to	to	IN
cord-306424-gf0bglm0	168	14	spatial	spatial	JJ
cord-306424-gf0bglm0	168	15	disorganization	disorganization	NN
cord-306424-gf0bglm0	168	16	of	of	IN
cord-306424-gf0bglm0	168	17	the	the	DT
cord-306424-gf0bglm0	168	18	antiviral	antiviral	JJ
cord-306424-gf0bglm0	168	19	innate	innate	JJ
cord-306424-gf0bglm0	168	20	immune	immune	JJ
cord-306424-gf0bglm0	168	21	system	system	NN
cord-306424-gf0bglm0	168	22	,	,	,
cord-306424-gf0bglm0	168	23	and	and	CC
cord-306424-gf0bglm0	168	24	future	future	JJ
cord-306424-gf0bglm0	168	25	studies	study	NNS
cord-306424-gf0bglm0	168	26	will	will	MD
cord-306424-gf0bglm0	168	27	hopefully	hopefully	RB
cord-306424-gf0bglm0	168	28	elucidate	elucidate	VB
cord-306424-gf0bglm0	168	29	the	the	DT
cord-306424-gf0bglm0	168	30	consequences	consequence	NNS
cord-306424-gf0bglm0	168	31	of	of	IN
cord-306424-gf0bglm0	168	32	this	this	DT
cord-306424-gf0bglm0	168	33	phenomenon	phenomenon	NN
cord-306424-gf0bglm0	168	34	in	in	IN
cord-306424-gf0bglm0	168	35	the	the	DT
cord-306424-gf0bglm0	168	36	context	context	NN
cord-306424-gf0bglm0	168	37	of	of	IN
cord-306424-gf0bglm0	168	38	other	other	JJ
cord-306424-gf0bglm0	168	39	cellular	cellular	JJ
cord-306424-gf0bglm0	168	40	compartments	compartment	NNS
cord-306424-gf0bglm0	168	41	and	and	CC
cord-306424-gf0bglm0	168	42	viruses	virus	NNS
cord-306424-gf0bglm0	168	43	.	.	.
cord-306424-gf0bglm0	169	1	Assuming	assume	VBG
cord-306424-gf0bglm0	169	2	that	that	IN
cord-306424-gf0bglm0	169	3	ROs	ROs	NNP
cord-306424-gf0bglm0	169	4	impair	impair	VB
cord-306424-gf0bglm0	169	5	antiviral	antiviral	JJ
cord-306424-gf0bglm0	169	6	signaling	signaling	NN
cord-306424-gf0bglm0	169	7	by	by	IN
cord-306424-gf0bglm0	169	8	shielding	shield	VBG
cord-306424-gf0bglm0	169	9	viral	viral	JJ
cord-306424-gf0bglm0	169	10	RNA	RNA	NNP
cord-306424-gf0bglm0	169	11	from	from	IN
cord-306424-gf0bglm0	169	12	the	the	DT
cord-306424-gf0bglm0	169	13	host	host	NN
cord-306424-gf0bglm0	169	14	,	,	,
cord-306424-gf0bglm0	169	15	it	-PRON-	PRP
cord-306424-gf0bglm0	169	16	is	be	VBZ
cord-306424-gf0bglm0	169	17	tempting	tempt	VBG
cord-306424-gf0bglm0	169	18	to	to	TO
cord-306424-gf0bglm0	169	19	hypothesize	hypothesize	VB
cord-306424-gf0bglm0	169	20	the	the	DT
cord-306424-gf0bglm0	169	21	existence	existence	NN
cord-306424-gf0bglm0	169	22	of	of	IN
cord-306424-gf0bglm0	169	23	host	host	NN
cord-306424-gf0bglm0	169	24	cell	cell	NN
cord-306424-gf0bglm0	169	25	mechanisms	mechanism	NNS
cord-306424-gf0bglm0	169	26	aimed	aim	VBN
cord-306424-gf0bglm0	169	27	to	to	TO
cord-306424-gf0bglm0	169	28	disrupt	disrupt	VB
cord-306424-gf0bglm0	169	29	ROs	ROs	NNP
cord-306424-gf0bglm0	169	30	,	,	,
cord-306424-gf0bglm0	169	31	thereby	thereby	RB
cord-306424-gf0bglm0	169	32	exposing	expose	VBG
cord-306424-gf0bglm0	169	33	viral	viral	JJ
cord-306424-gf0bglm0	169	34	RNA	RNA	NNP
cord-306424-gf0bglm0	169	35	and	and	CC
cord-306424-gf0bglm0	169	36	promoting	promote	VBG
cord-306424-gf0bglm0	169	37	antiviral	antiviral	JJ
cord-306424-gf0bglm0	169	38	signaling	signaling	NN
cord-306424-gf0bglm0	169	39	.	.	.
cord-306424-gf0bglm0	170	1	The	the	DT
cord-306424-gf0bglm0	170	2	fact	fact	NN
cord-306424-gf0bglm0	170	3	that	that	IN
cord-306424-gf0bglm0	170	4	+	+	SYM
cord-306424-gf0bglm0	170	5	RNA	RNA	NNP
cord-306424-gf0bglm0	170	6	viruses	virus	NNS
cord-306424-gf0bglm0	170	7	display	display	VBP
cord-306424-gf0bglm0	170	8	such	such	JJ
cord-306424-gf0bglm0	170	9	elaborate	elaborate	JJ
cord-306424-gf0bglm0	170	10	activities	activity	NNS
cord-306424-gf0bglm0	170	11	to	to	TO
cord-306424-gf0bglm0	170	12	inhibit	inhibit	VB
cord-306424-gf0bglm0	170	13	viral	viral	JJ
cord-306424-gf0bglm0	170	14	RNA	RNA	NNP
cord-306424-gf0bglm0	170	15	recognition	recognition	NN
cord-306424-gf0bglm0	170	16	and	and	CC
cord-306424-gf0bglm0	170	17	subsequent	subsequent	JJ
cord-306424-gf0bglm0	170	18	signaling	signaling	NN
cord-306424-gf0bglm0	170	19	,	,	,
cord-306424-gf0bglm0	170	20	as	as	IN
cord-306424-gf0bglm0	170	21	detailed	detail	VBN
cord-306424-gf0bglm0	170	22	in	in	IN
cord-306424-gf0bglm0	170	23	the	the	DT
cord-306424-gf0bglm0	170	24	former	former	JJ
cord-306424-gf0bglm0	170	25	paragraphs	paragraph	NNS
cord-306424-gf0bglm0	170	26	,	,	,
cord-306424-gf0bglm0	170	27	supports	support	VBZ
cord-306424-gf0bglm0	170	28	the	the	DT
cord-306424-gf0bglm0	170	29	view	view	NN
cord-306424-gf0bglm0	170	30	that	that	IN
cord-306424-gf0bglm0	170	31	disruption	disruption	NN
cord-306424-gf0bglm0	170	32	of	of	IN
cord-306424-gf0bglm0	170	33	RO	ro	NN
cord-306424-gf0bglm0	170	34	integrity	integrity	NN
cord-306424-gf0bglm0	170	35	is	be	VBZ
cord-306424-gf0bglm0	170	36	a	a	DT
cord-306424-gf0bglm0	170	37	situation	situation	NN
cord-306424-gf0bglm0	170	38	these	these	DT
cord-306424-gf0bglm0	170	39	viruses	virus	NNS
cord-306424-gf0bglm0	170	40	anticipate	anticipate	VBP
cord-306424-gf0bglm0	170	41	dealing	deal	VBG
cord-306424-gf0bglm0	170	42	with	with	IN
cord-306424-gf0bglm0	170	43	.	.	.
cord-306424-gf0bglm0	171	1	However	however	RB
cord-306424-gf0bglm0	171	2	,	,	,
cord-306424-gf0bglm0	171	3	evidence	evidence	NN
cord-306424-gf0bglm0	171	4	suggesting	suggest	VBG
cord-306424-gf0bglm0	171	5	targeting	target	VBG
cord-306424-gf0bglm0	171	6	of	of	IN
cord-306424-gf0bglm0	171	7	ROs	ro	NNS
cord-306424-gf0bglm0	171	8	by	by	IN
cord-306424-gf0bglm0	171	9	the	the	DT
cord-306424-gf0bglm0	171	10	innate	innate	JJ
cord-306424-gf0bglm0	171	11	immune	immune	JJ
cord-306424-gf0bglm0	171	12	system	system	NN
cord-306424-gf0bglm0	171	13	is	be	VBZ
cord-306424-gf0bglm0	171	14	still	still	RB
cord-306424-gf0bglm0	171	15	scarce	scarce	JJ
cord-306424-gf0bglm0	171	16	,	,	,
cord-306424-gf0bglm0	171	17	although	although	IN
cord-306424-gf0bglm0	171	18	it	-PRON-	PRP
cord-306424-gf0bglm0	171	19	was	be	VBD
cord-306424-gf0bglm0	171	20	reported	report	VBN
cord-306424-gf0bglm0	171	21	that	that	IN
cord-306424-gf0bglm0	171	22	HCV	HCV	NNP
cord-306424-gf0bglm0	171	23	ROs	ROs	NNP
cord-306424-gf0bglm0	171	24	are	be	VBP
cord-306424-gf0bglm0	171	25	attacked	attack	VBN
cord-306424-gf0bglm0	171	26	by	by	IN
cord-306424-gf0bglm0	171	27	the	the	DT
cord-306424-gf0bglm0	171	28	ISG	ISG	NNP
cord-306424-gf0bglm0	171	29	Viperin	Viperin	NNP
cord-306424-gf0bglm0	171	30	[	[	-LRB-
cord-306424-gf0bglm0	171	31	94	94	CD
cord-306424-gf0bglm0	171	32	]	]	-RRB-
cord-306424-gf0bglm0	171	33	.	.	.
cord-306424-gf0bglm0	172	1	Additionally	additionally	RB
cord-306424-gf0bglm0	172	2	,	,	,
cord-306424-gf0bglm0	172	3	25-hydroxycholesterol	25-hydroxycholesterol	CD
cord-306424-gf0bglm0	172	4	,	,	,
cord-306424-gf0bglm0	172	5	a	a	DT
cord-306424-gf0bglm0	172	6	product	product	NN
cord-306424-gf0bglm0	172	7	produced	produce	VBN
cord-306424-gf0bglm0	172	8	by	by	IN
cord-306424-gf0bglm0	172	9	the	the	DT
cord-306424-gf0bglm0	172	10	ISG	ISG	NNP
cord-306424-gf0bglm0	172	11	cholesterol	cholesterol	NN
cord-306424-gf0bglm0	172	12	25-hydroxylase	25-hydroxylase	CD
cord-306424-gf0bglm0	172	13	also	also	RB
cord-306424-gf0bglm0	172	14	modifies	modify	VBZ
cord-306424-gf0bglm0	172	15	HCV	HCV	NNP
cord-306424-gf0bglm0	172	16	replication	replication	NN
cord-306424-gf0bglm0	172	17	organelles	organelle	NNS
cord-306424-gf0bglm0	172	18	[	[	-LRB-
cord-306424-gf0bglm0	172	19	112	112	CD
cord-306424-gf0bglm0	172	20	,	,	,
cord-306424-gf0bglm0	172	21	113	113	CD
cord-306424-gf0bglm0	172	22	]	]	-RRB-
cord-306424-gf0bglm0	172	23	.	.	.
cord-306424-gf0bglm0	173	1	Recently	recently	RB
cord-306424-gf0bglm0	173	2	,	,	,
cord-306424-gf0bglm0	173	3	our	-PRON-	PRP$
cord-306424-gf0bglm0	173	4	lab	lab	NN
cord-306424-gf0bglm0	173	5	published	publish	VBD
cord-306424-gf0bglm0	173	6	a	a	DT
cord-306424-gf0bglm0	173	7	study	study	NN
cord-306424-gf0bglm0	173	8	suggesting	suggest	VBG
cord-306424-gf0bglm0	173	9	that	that	IN
cord-306424-gf0bglm0	173	10	IFN	IFN	NNP
cord-306424-gf0bglm0	173	11	-	-	HYPH
cord-306424-gf0bglm0	173	12	b	b	NNP
cord-306424-gf0bglm0	173	13	signaling	signaling	NN
cord-306424-gf0bglm0	173	14	also	also	RB
cord-306424-gf0bglm0	173	15	negatively	negatively	RB
cord-306424-gf0bglm0	173	16	influences	influence	VBZ
cord-306424-gf0bglm0	173	17	arterivirus	arterivirus	NNP
cord-306424-gf0bglm0	173	18	ROs	ROs	NNP
cord-306424-gf0bglm0	173	19	,	,	,
cord-306424-gf0bglm0	173	20	since	since	IN
cord-306424-gf0bglm0	173	21	significantly	significantly	RB
cord-306424-gf0bglm0	173	22	less	less	RBR
cord-306424-gf0bglm0	173	23	were	be	VBD
cord-306424-gf0bglm0	173	24	formed	form	VBN
cord-306424-gf0bglm0	173	25	and	and	CC
cord-306424-gf0bglm0	173	26	remaining	remain	VBG
cord-306424-gf0bglm0	173	27	structures	structure	NNS
cord-306424-gf0bglm0	173	28	showed	show	VBD
cord-306424-gf0bglm0	173	29	drastically	drastically	RB
cord-306424-gf0bglm0	173	30	different	different	JJ
cord-306424-gf0bglm0	173	31	morphology	morphology	NN
cord-306424-gf0bglm0	173	32	after	after	IN
cord-306424-gf0bglm0	173	33	IFN	IFN	NNP
cord-306424-gf0bglm0	173	34	-	-	HYPH
cord-306424-gf0bglm0	173	35	b	b	NN
cord-306424-gf0bglm0	173	36	treatment	treatment	NN
cord-306424-gf0bglm0	173	37	.	.	.
cord-306424-gf0bglm0	174	1	The	the	DT
cord-306424-gf0bglm0	174	2	results	result	NNS
cord-306424-gf0bglm0	174	3	suggested	suggest	VBD
cord-306424-gf0bglm0	174	4	that	that	IN
cord-306424-gf0bglm0	174	5	the	the	DT
cord-306424-gf0bglm0	174	6	treatment	treatment	NN
cord-306424-gf0bglm0	174	7	interrupted	interrupt	VBD
cord-306424-gf0bglm0	174	8	biogenesis	biogenesis	NN
cord-306424-gf0bglm0	174	9	of	of	IN
cord-306424-gf0bglm0	174	10	these	these	DT
cord-306424-gf0bglm0	174	11	membrane	membrane	NN
cord-306424-gf0bglm0	174	12	structures	structure	NNS
cord-306424-gf0bglm0	174	13	rather	rather	RB
cord-306424-gf0bglm0	174	14	than	than	IN
cord-306424-gf0bglm0	174	15	breaking	break	VBG
cord-306424-gf0bglm0	174	16	down	down	RP
cord-306424-gf0bglm0	174	17	structures	structure	NNS
cord-306424-gf0bglm0	174	18	that	that	WDT
cord-306424-gf0bglm0	174	19	were	be	VBD
cord-306424-gf0bglm0	174	20	already	already	RB
cord-306424-gf0bglm0	174	21	made	make	VBN
cord-306424-gf0bglm0	174	22	[	[	-LRB-
cord-306424-gf0bglm0	174	23	114	114	CD
cord-306424-gf0bglm0	174	24	]	]	-RRB-
cord-306424-gf0bglm0	174	25	.	.	.
cord-306424-gf0bglm0	175	1	Interestingly	interestingly	RB
cord-306424-gf0bglm0	175	2	,	,	,
cord-306424-gf0bglm0	175	3	neither	neither	CC
cord-306424-gf0bglm0	175	4	Viperin	Viperin	NNP
cord-306424-gf0bglm0	175	5	nor	nor	CC
cord-306424-gf0bglm0	175	6	25-hydroxycholesterol	25-hydroxycholesterol	CD
cord-306424-gf0bglm0	175	7	was	be	VBD
cord-306424-gf0bglm0	175	8	involved	involve	VBN
cord-306424-gf0bglm0	175	9	in	in	IN
cord-306424-gf0bglm0	175	10	the	the	DT
cord-306424-gf0bglm0	175	11	observed	observed	JJ
cord-306424-gf0bglm0	175	12	effects	effect	NNS
cord-306424-gf0bglm0	175	13	,	,	,
cord-306424-gf0bglm0	175	14	and	and	CC
cord-306424-gf0bglm0	175	15	the	the	DT
cord-306424-gf0bglm0	175	16	mechanistic	mechanistic	JJ
cord-306424-gf0bglm0	175	17	details	detail	NNS
cord-306424-gf0bglm0	175	18	therefore	therefore	RB
cord-306424-gf0bglm0	175	19	have	have	VBP
cord-306424-gf0bglm0	175	20	to	to	TO
cord-306424-gf0bglm0	175	21	be	be	VB
cord-306424-gf0bglm0	175	22	further	further	RB
cord-306424-gf0bglm0	175	23	investigated	investigate	VBN
cord-306424-gf0bglm0	175	24	.	.	.
cord-306424-gf0bglm0	176	1	Other	other	JJ
cord-306424-gf0bglm0	176	2	recent	recent	JJ
cord-306424-gf0bglm0	176	3	data	datum	NNS
cord-306424-gf0bglm0	176	4	suggest	suggest	VBP
cord-306424-gf0bglm0	176	5	that	that	IN
cord-306424-gf0bglm0	176	6	there	there	EX
cord-306424-gf0bglm0	176	7	may	may	MD
cord-306424-gf0bglm0	176	8	indeed	indeed	RB
cord-306424-gf0bglm0	176	9	be	be	VB
cord-306424-gf0bglm0	176	10	specific	specific	JJ
cord-306424-gf0bglm0	176	11	mechanisms	mechanism	NNS
cord-306424-gf0bglm0	176	12	by	by	IN
cord-306424-gf0bglm0	176	13	which	which	WDT
cord-306424-gf0bglm0	176	14	the	the	DT
cord-306424-gf0bglm0	176	15	innate	innate	JJ
cord-306424-gf0bglm0	176	16	immune	immune	JJ
cord-306424-gf0bglm0	176	17	system	system	NN
cord-306424-gf0bglm0	176	18	tags	tag	NNS
cord-306424-gf0bglm0	176	19	and	and	CC
cord-306424-gf0bglm0	176	20	disrupts	disrupt	VBZ
cord-306424-gf0bglm0	176	21	so	so	RB
cord-306424-gf0bglm0	176	22	-	-	HYPH
cord-306424-gf0bglm0	176	23	called	call	VBN
cord-306424-gf0bglm0	176	24	non	non	JJ
cord-306424-gf0bglm0	176	25	-	-	JJ
cord-306424-gf0bglm0	176	26	or	or	CC
cord-306424-gf0bglm0	176	27	aberrant	aberrant	JJ
cord-306424-gf0bglm0	176	28	-	-	HYPH
cord-306424-gf0bglm0	176	29	self	self	NN
cord-306424-gf0bglm0	176	30	membrane	membrane	NN
cord-306424-gf0bglm0	176	31	structures	structure	NNS
cord-306424-gf0bglm0	176	32	in	in	IN
cord-306424-gf0bglm0	176	33	the	the	DT
cord-306424-gf0bglm0	176	34	cell	cell	NN
cord-306424-gf0bglm0	176	35	[	[	-LRB-
cord-306424-gf0bglm0	176	36	115	115	CD
cord-306424-gf0bglm0	176	37	]	]	-RRB-
cord-306424-gf0bglm0	176	38	,	,	,
cord-306424-gf0bglm0	176	39	which	which	WDT
cord-306424-gf0bglm0	176	40	could	could	MD
cord-306424-gf0bglm0	176	41	include	include	VB
cord-306424-gf0bglm0	176	42	viral	viral	JJ
cord-306424-gf0bglm0	176	43	ROs	ro	NNS
cord-306424-gf0bglm0	176	44	.	.	.
cord-306424-gf0bglm0	177	1	Most	Most	JJS
cord-306424-gf0bglm0	177	2	data	datum	NNS
cord-306424-gf0bglm0	177	3	originate	originate	VBP
cord-306424-gf0bglm0	177	4	from	from	IN
cord-306424-gf0bglm0	177	5	studies	study	NNS
cord-306424-gf0bglm0	177	6	focusing	focus	VBG
cord-306424-gf0bglm0	177	7	on	on	IN
cord-306424-gf0bglm0	177	8	bacteria	bacteria	NNS
cord-306424-gf0bglm0	177	9	,	,	,
cord-306424-gf0bglm0	177	10	fungi	fungus	NNS
cord-306424-gf0bglm0	177	11	,	,	,
cord-306424-gf0bglm0	177	12	or	or	CC
cord-306424-gf0bglm0	177	13	parasites	parasite	NNS
cord-306424-gf0bglm0	177	14	that	that	WDT
cord-306424-gf0bglm0	177	15	reside	reside	VBP
cord-306424-gf0bglm0	177	16	in	in	IN
cord-306424-gf0bglm0	177	17	rearranged	rearrange	VBN
cord-306424-gf0bglm0	177	18	membranes	membrane	NNS
cord-306424-gf0bglm0	177	19	,	,	,
cord-306424-gf0bglm0	177	20	known	know	VBN
cord-306424-gf0bglm0	177	21	as	as	IN
cord-306424-gf0bglm0	177	22	pathogen	pathogen	NN
cord-306424-gf0bglm0	177	23	-	-	HYPH
cord-306424-gf0bglm0	177	24	containing	contain	VBG
cord-306424-gf0bglm0	177	25	vacuoles	vacuole	NNS
cord-306424-gf0bglm0	177	26	(	(	-LRB-
cord-306424-gf0bglm0	177	27	PVs	pv	NNS
cord-306424-gf0bglm0	177	28	)	)	-RRB-
cord-306424-gf0bglm0	177	29	,	,	,
cord-306424-gf0bglm0	177	30	which	which	WDT
cord-306424-gf0bglm0	177	31	prevent	prevent	VBP
cord-306424-gf0bglm0	177	32	detection	detection	NN
cord-306424-gf0bglm0	177	33	of	of	IN
cord-306424-gf0bglm0	177	34	cytosolic	cytosolic	JJ
cord-306424-gf0bglm0	177	35	innate	innate	JJ
cord-306424-gf0bglm0	177	36	immune	immune	JJ
cord-306424-gf0bglm0	177	37	sensors	sensor	NNS
cord-306424-gf0bglm0	177	38	in	in	IN
cord-306424-gf0bglm0	177	39	a	a	DT
cord-306424-gf0bglm0	177	40	similar	similar	JJ
cord-306424-gf0bglm0	177	41	way	way	NN
cord-306424-gf0bglm0	177	42	as	as	IN
cord-306424-gf0bglm0	177	43	viral	viral	JJ
cord-306424-gf0bglm0	177	44	ROs	ro	NNS
cord-306424-gf0bglm0	177	45	are	be	VBP
cord-306424-gf0bglm0	177	46	thought	think	VBN
cord-306424-gf0bglm0	177	47	to	to	TO
cord-306424-gf0bglm0	177	48	do	do	VB
cord-306424-gf0bglm0	177	49	.	.	.
cord-306424-gf0bglm0	178	1	Multiple	multiple	JJ
cord-306424-gf0bglm0	178	2	studies	study	NNS
cord-306424-gf0bglm0	178	3	found	find	VBD
cord-306424-gf0bglm0	178	4	that	that	IN
cord-306424-gf0bglm0	178	5	enzymes	enzyme	NNS
cord-306424-gf0bglm0	178	6	capable	capable	JJ
cord-306424-gf0bglm0	178	7	of	of	IN
cord-306424-gf0bglm0	178	8	disrupting	disrupt	VBG
cord-306424-gf0bglm0	178	9	PVs	pv	NNS
cord-306424-gf0bglm0	178	10	are	be	VBP
cord-306424-gf0bglm0	178	11	GTPases	gtpase	NNS
cord-306424-gf0bglm0	178	12	,	,	,
cord-306424-gf0bglm0	178	13	such	such	JJ
cord-306424-gf0bglm0	178	14	as	as	IN
cord-306424-gf0bglm0	178	15	effector	effector	JJ
cord-306424-gf0bglm0	178	16	immunity	immunity	NN
cord-306424-gf0bglm0	178	17	-	-	HYPH
cord-306424-gf0bglm0	178	18	related	relate	VBN
cord-306424-gf0bglm0	178	19	p47	p47	NN
cord-306424-gf0bglm0	178	20	GTPases	gtpase	NNS
cord-306424-gf0bglm0	178	21	(	(	-LRB-
cord-306424-gf0bglm0	178	22	IRGs	IRGs	NNP
cord-306424-gf0bglm0	178	23	)	)	-RRB-
cord-306424-gf0bglm0	178	24	and	and	CC
cord-306424-gf0bglm0	178	25	guanylatebinding	guanylatebinde	VBG
cord-306424-gf0bglm0	178	26	proteins	protein	NNS
cord-306424-gf0bglm0	178	27	(	(	-LRB-
cord-306424-gf0bglm0	178	28	GBPs	GBPs	NNP
cord-306424-gf0bglm0	178	29	)	)	-RRB-
cord-306424-gf0bglm0	178	30	,	,	,
cord-306424-gf0bglm0	178	31	which	which	WDT
cord-306424-gf0bglm0	178	32	are	be	VBP
cord-306424-gf0bglm0	178	33	part	part	NN
cord-306424-gf0bglm0	178	34	of	of	IN
cord-306424-gf0bglm0	178	35	a	a	DT
cord-306424-gf0bglm0	178	36	family	family	NN
cord-306424-gf0bglm0	178	37	which	which	WDT
cord-306424-gf0bglm0	178	38	we	-PRON-	PRP
cord-306424-gf0bglm0	178	39	will	will	MD
cord-306424-gf0bglm0	178	40	refer	refer	VB
cord-306424-gf0bglm0	178	41	to	to	IN
cord-306424-gf0bglm0	178	42	as	as	IN
cord-306424-gf0bglm0	178	43	IFN	IFN	NNP
cord-306424-gf0bglm0	178	44	-	-	HYPH
cord-306424-gf0bglm0	178	45	inducible	inducible	JJ
cord-306424-gf0bglm0	178	46	GTPases	gtpase	NNS
cord-306424-gf0bglm0	178	47	[	[	-LRB-
cord-306424-gf0bglm0	178	48	116	116	CD
cord-306424-gf0bglm0	178	49	]	]	-RRB-
cord-306424-gf0bglm0	178	50	.	.	.
cord-306424-gf0bglm0	179	1	Expression	expression	NN
cord-306424-gf0bglm0	179	2	of	of	IN
cord-306424-gf0bglm0	179	3	IRGs	irg	NNS
cord-306424-gf0bglm0	179	4	and	and	CC
cord-306424-gf0bglm0	179	5	GBPs	GBPs	NNPS
cord-306424-gf0bglm0	179	6	is	be	VBZ
cord-306424-gf0bglm0	179	7	induced	induce	VBN
cord-306424-gf0bglm0	179	8	upon	upon	IN
cord-306424-gf0bglm0	179	9	IFN	IFN	NNP
cord-306424-gf0bglm0	179	10	-	-	HYPH
cord-306424-gf0bglm0	179	11	g	g	NN
cord-306424-gf0bglm0	179	12	stimulation	stimulation	NN
cord-306424-gf0bglm0	179	13	,	,	,
cord-306424-gf0bglm0	179	14	and	and	CC
cord-306424-gf0bglm0	179	15	leads	lead	VBZ
cord-306424-gf0bglm0	179	16	to	to	IN
cord-306424-gf0bglm0	179	17	their	-PRON-	PRP$
cord-306424-gf0bglm0	179	18	accumulation	accumulation	NN
cord-306424-gf0bglm0	179	19	on	on	IN
cord-306424-gf0bglm0	179	20	PVs	pv	NNS
cord-306424-gf0bglm0	179	21	.	.	.
cord-306424-gf0bglm0	180	1	Subsequently	subsequently	RB
cord-306424-gf0bglm0	180	2	,	,	,
cord-306424-gf0bglm0	180	3	activation	activation	NN
cord-306424-gf0bglm0	180	4	of	of	IN
cord-306424-gf0bglm0	180	5	these	these	DT
cord-306424-gf0bglm0	180	6	GTPases	gtpase	NNS
cord-306424-gf0bglm0	180	7	due	due	IN
cord-306424-gf0bglm0	180	8	to	to	IN
cord-306424-gf0bglm0	180	9	the	the	DT
cord-306424-gf0bglm0	180	10	exchange	exchange	NN
cord-306424-gf0bglm0	180	11	of	of	IN
cord-306424-gf0bglm0	180	12	GDP	GDP	NNP
cord-306424-gf0bglm0	180	13	for	for	IN
cord-306424-gf0bglm0	180	14	GTP	GTP	NNP
cord-306424-gf0bglm0	180	15	results	result	NNS
cord-306424-gf0bglm0	180	16	in	in	IN
cord-306424-gf0bglm0	180	17	membrane	membrane	NN
cord-306424-gf0bglm0	180	18	disruption	disruption	NN
cord-306424-gf0bglm0	180	19	as	as	IN
cord-306424-gf0bglm0	180	20	a	a	DT
cord-306424-gf0bglm0	180	21	consequence	consequence	NN
cord-306424-gf0bglm0	180	22	of	of	IN
cord-306424-gf0bglm0	180	23	their	-PRON-	PRP$
cord-306424-gf0bglm0	180	24	dynamin	dynamin	NN
cord-306424-gf0bglm0	180	25	-	-	HYPH
cord-306424-gf0bglm0	180	26	like	like	JJ
cord-306424-gf0bglm0	180	27	activity	activity	NN
cord-306424-gf0bglm0	180	28	[	[	-LRB-
cord-306424-gf0bglm0	180	29	117	117	CD
cord-306424-gf0bglm0	180	30	]	]	-RRB-
cord-306424-gf0bglm0	180	31	.	.	.
cord-306424-gf0bglm0	181	1	To	to	TO
cord-306424-gf0bglm0	181	2	prevent	prevent	VB
cord-306424-gf0bglm0	181	3	aspecific	aspecific	NN
cord-306424-gf0bglm0	181	4	disruption	disruption	NN
cord-306424-gf0bglm0	181	5	,	,	,
cord-306424-gf0bglm0	181	6	host	host	NN
cord-306424-gf0bglm0	181	7	cell	cell	NN
cord-306424-gf0bglm0	181	8	membranes	membrane	NNS
cord-306424-gf0bglm0	181	9	contain	contain	VBP
cord-306424-gf0bglm0	181	10	a	a	DT
cord-306424-gf0bglm0	181	11	set	set	NN
cord-306424-gf0bglm0	181	12	of	of	IN
cord-306424-gf0bglm0	181	13	proteins	protein	NNS
cord-306424-gf0bglm0	181	14	that	that	WDT
cord-306424-gf0bglm0	181	15	inhibit	inhibit	VBP
cord-306424-gf0bglm0	181	16	GTPase	GTPase	NNP
cord-306424-gf0bglm0	181	17	activity	activity	NN
cord-306424-gf0bglm0	181	18	,	,	,
cord-306424-gf0bglm0	181	19	known	know	VBN
cord-306424-gf0bglm0	181	20	as	as	IN
cord-306424-gf0bglm0	181	21	'	'	''
cord-306424-gf0bglm0	181	22	'	'	''
cord-306424-gf0bglm0	181	23	guard	guard	NN
cord-306424-gf0bglm0	181	24	proteins	protein	NNS
cord-306424-gf0bglm0	181	25	'	'	POS
cord-306424-gf0bglm0	181	26	'	'	''
cord-306424-gf0bglm0	181	27	[	[	-LRB-
cord-306424-gf0bglm0	181	28	118	118	CD
cord-306424-gf0bglm0	181	29	]	]	-RRB-
cord-306424-gf0bglm0	181	30	.	.	.
cord-306424-gf0bglm0	182	1	Wellstudied	wellstudied	JJ
cord-306424-gf0bglm0	182	2	pathogens	pathogen	NNS
cord-306424-gf0bglm0	182	3	in	in	IN
cord-306424-gf0bglm0	182	4	the	the	DT
cord-306424-gf0bglm0	182	5	context	context	NN
cord-306424-gf0bglm0	182	6	of	of	IN
cord-306424-gf0bglm0	182	7	this	this	DT
cord-306424-gf0bglm0	182	8	process	process	NN
cord-306424-gf0bglm0	182	9	are	be	VBP
cord-306424-gf0bglm0	182	10	the	the	DT
cord-306424-gf0bglm0	182	11	protozoan	protozoan	NN
cord-306424-gf0bglm0	182	12	parasite	parasite	VBP
cord-306424-gf0bglm0	182	13	Toxoplasma	toxoplasma	NN
cord-306424-gf0bglm0	182	14	gondii	gondii	NN
cord-306424-gf0bglm0	182	15	(	(	-LRB-
cord-306424-gf0bglm0	182	16	T.	T.	NNP
cord-306424-gf0bglm0	182	17	gondii	gondii	NNP
cord-306424-gf0bglm0	182	18	)	)	-RRB-
cord-306424-gf0bglm0	182	19	,	,	,
cord-306424-gf0bglm0	182	20	the	the	DT
cord-306424-gf0bglm0	182	21	bacterium	bacterium	NN
cord-306424-gf0bglm0	182	22	Chlamydia	Chlamydia	NNP
cord-306424-gf0bglm0	182	23	trachomatis	trachomatis	NN
cord-306424-gf0bglm0	182	24	and	and	CC
cord-306424-gf0bglm0	182	25	the	the	DT
cord-306424-gf0bglm0	182	26	microsporidian	microsporidian	JJ
cord-306424-gf0bglm0	182	27	Encephalitozoon	Encephalitozoon	NNP
cord-306424-gf0bglm0	182	28	cuniculi	cuniculi	NNP
cord-306424-gf0bglm0	182	29	[	[	-LRB-
cord-306424-gf0bglm0	182	30	119	119	CD
cord-306424-gf0bglm0	182	31	]	]	-RRB-
cord-306424-gf0bglm0	182	32	[	[	-LRB-
cord-306424-gf0bglm0	182	33	120	120	CD
cord-306424-gf0bglm0	182	34	]	]	-RRB-
cord-306424-gf0bglm0	182	35	[	[	-LRB-
cord-306424-gf0bglm0	182	36	121	121	CD
cord-306424-gf0bglm0	182	37	]	]	-RRB-
cord-306424-gf0bglm0	182	38	[	[	-LRB-
cord-306424-gf0bglm0	182	39	122	122	CD
cord-306424-gf0bglm0	182	40	]	]	-RRB-
cord-306424-gf0bglm0	182	41	[	[	-LRB-
cord-306424-gf0bglm0	182	42	123	123	CD
cord-306424-gf0bglm0	182	43	]	]	-RRB-
cord-306424-gf0bglm0	182	44	[	[	-LRB-
cord-306424-gf0bglm0	182	45	124	124	CD
cord-306424-gf0bglm0	182	46	]	]	-RRB-
cord-306424-gf0bglm0	182	47	[	[	-LRB-
cord-306424-gf0bglm0	182	48	125	125	CD
cord-306424-gf0bglm0	182	49	]	]	-RRB-
cord-306424-gf0bglm0	182	50	.	.	.
cord-306424-gf0bglm0	183	1	Although	although	IN
cord-306424-gf0bglm0	183	2	it	-PRON-	PRP
cord-306424-gf0bglm0	183	3	remains	remain	VBZ
cord-306424-gf0bglm0	183	4	unclear	unclear	JJ
cord-306424-gf0bglm0	183	5	for	for	IN
cord-306424-gf0bglm0	183	6	most	most	JJS
cord-306424-gf0bglm0	183	7	of	of	IN
cord-306424-gf0bglm0	183	8	these	these	DT
cord-306424-gf0bglm0	183	9	pathogens	pathogen	NNS
cord-306424-gf0bglm0	183	10	how	how	WRB
cord-306424-gf0bglm0	183	11	IFN	IFN	NNP
cord-306424-gf0bglm0	183	12	-	-	HYPH
cord-306424-gf0bglm0	183	13	inducible	inducible	JJ
cord-306424-gf0bglm0	183	14	GTPases	gtpase	NNS
cord-306424-gf0bglm0	183	15	are	be	VBP
cord-306424-gf0bglm0	183	16	recruited	recruit	VBN
cord-306424-gf0bglm0	183	17	towards	towards	IN
cord-306424-gf0bglm0	183	18	PVs	pv	NNS
cord-306424-gf0bglm0	183	19	,	,	,
cord-306424-gf0bglm0	183	20	recent	recent	JJ
cord-306424-gf0bglm0	183	21	studies	study	NNS
cord-306424-gf0bglm0	183	22	on	on	IN
cord-306424-gf0bglm0	183	23	T.	T.	NNP
cord-306424-gf0bglm0	183	24	gondii	gondii	NNP
cord-306424-gf0bglm0	183	25	infection	infection	NN
cord-306424-gf0bglm0	183	26	demonstrated	demonstrate	VBD
cord-306424-gf0bglm0	183	27	that	that	IN
cord-306424-gf0bglm0	183	28	host	host	NN
cord-306424-gf0bglm0	183	29	cells	cell	NNS
cord-306424-gf0bglm0	183	30	label	label	VBP
cord-306424-gf0bglm0	183	31	these	these	DT
cord-306424-gf0bglm0	183	32	membrane	membrane	NN
cord-306424-gf0bglm0	183	33	structures	structure	NNS
cord-306424-gf0bglm0	183	34	,	,	,
cord-306424-gf0bglm0	183	35	for	for	IN
cord-306424-gf0bglm0	183	36	example	example	NN
cord-306424-gf0bglm0	183	37	with	with	IN
cord-306424-gf0bglm0	183	38	various	various	JJ
cord-306424-gf0bglm0	183	39	forms	form	NNS
cord-306424-gf0bglm0	183	40	of	of	IN
cord-306424-gf0bglm0	183	41	microtubule	microtubule	NN
cord-306424-gf0bglm0	183	42	-	-	HYPH
cord-306424-gf0bglm0	183	43	associated	associate	VBN
cord-306424-gf0bglm0	183	44	protein	protein	NN
cord-306424-gf0bglm0	183	45	1A/1B	1a/1b	CD
cord-306424-gf0bglm0	183	46	-	-	HYPH
cord-306424-gf0bglm0	183	47	light	light	NN
cord-306424-gf0bglm0	183	48	chain	chain	NN
cord-306424-gf0bglm0	183	49	3	3	CD
cord-306424-gf0bglm0	184	1	(	(	-LRB-
cord-306424-gf0bglm0	184	2	LC3	LC3	NNP
cord-306424-gf0bglm0	184	3	)	)	-RRB-
cord-306424-gf0bglm0	185	1	to	to	TO
cord-306424-gf0bglm0	185	2	initiate	initiate	VB
cord-306424-gf0bglm0	185	3	this	this	DT
cord-306424-gf0bglm0	185	4	process	process	NN
cord-306424-gf0bglm0	185	5	[	[	-LRB-
cord-306424-gf0bglm0	185	6	122	122	CD
cord-306424-gf0bglm0	185	7	]	]	-RRB-
cord-306424-gf0bglm0	186	1	[	[	-LRB-
cord-306424-gf0bglm0	186	2	123	123	CD
cord-306424-gf0bglm0	186	3	]	]	-RRB-
cord-306424-gf0bglm0	186	4	[	[	-LRB-
cord-306424-gf0bglm0	186	5	124	124	CD
cord-306424-gf0bglm0	186	6	]	]	-RRB-
cord-306424-gf0bglm0	187	1	[	[	-LRB-
cord-306424-gf0bglm0	187	2	125	125	CD
cord-306424-gf0bglm0	187	3	]	]	-RRB-
cord-306424-gf0bglm0	188	1	(	(	-LRB-
cord-306424-gf0bglm0	188	2	Fig	Fig	NNP
cord-306424-gf0bglm0	188	3	.	.	NNP
cord-306424-gf0bglm0	188	4	2	2	CD
cord-306424-gf0bglm0	188	5	)	)	-RRB-
cord-306424-gf0bglm0	188	6	.	.	.
cord-306424-gf0bglm0	189	1	LC3	LC3	NNP
cord-306424-gf0bglm0	189	2	is	be	VBZ
cord-306424-gf0bglm0	189	3	a	a	DT
cord-306424-gf0bglm0	189	4	well	well	RB
cord-306424-gf0bglm0	189	5	-	-	HYPH
cord-306424-gf0bglm0	189	6	known	know	VBN
cord-306424-gf0bglm0	189	7	factor	factor	NN
cord-306424-gf0bglm0	189	8	in	in	IN
cord-306424-gf0bglm0	189	9	the	the	DT
cord-306424-gf0bglm0	189	10	autophagy	autophagy	NN
cord-306424-gf0bglm0	189	11	pathway	pathway	NN
cord-306424-gf0bglm0	189	12	,	,	,
cord-306424-gf0bglm0	189	13	and	and	CC
cord-306424-gf0bglm0	189	14	several	several	JJ
cord-306424-gf0bglm0	189	15	forms	form	NNS
cord-306424-gf0bglm0	189	16	of	of	IN
cord-306424-gf0bglm0	189	17	LC3	lc3	NN
cord-306424-gf0bglm0	189	18	exist	exist	VBP
cord-306424-gf0bglm0	189	19	in	in	IN
cord-306424-gf0bglm0	189	20	the	the	DT
cord-306424-gf0bglm0	189	21	human	human	JJ
cord-306424-gf0bglm0	189	22	proteome	proteome	NN
cord-306424-gf0bglm0	189	23	,	,	,
cord-306424-gf0bglm0	189	24	which	which	WDT
cord-306424-gf0bglm0	189	25	seem	seem	VBP
cord-306424-gf0bglm0	189	26	to	to	TO
cord-306424-gf0bglm0	189	27	have	have	VB
cord-306424-gf0bglm0	189	28	overlapping	overlap	VBG
cord-306424-gf0bglm0	189	29	as	as	RB
cord-306424-gf0bglm0	189	30	well	well	RB
cord-306424-gf0bglm0	189	31	as	as	IN
cord-306424-gf0bglm0	189	32	distinct	distinct	JJ
cord-306424-gf0bglm0	189	33	functions	function	NNS
cord-306424-gf0bglm0	189	34	.	.	.
cord-306424-gf0bglm0	190	1	The	the	DT
cord-306424-gf0bglm0	190	2	human	human	JJ
cord-306424-gf0bglm0	190	3	genome	genome	NN
cord-306424-gf0bglm0	190	4	encodes	encode	VBZ
cord-306424-gf0bglm0	190	5	homologs	homolog	NNS
cord-306424-gf0bglm0	190	6	LC3A	LC3A	''
cord-306424-gf0bglm0	190	7	,	,	,
cord-306424-gf0bglm0	190	8	LC3B	lc3b	NN
cord-306424-gf0bglm0	190	9	,	,	,
cord-306424-gf0bglm0	190	10	and	and	CC
cord-306424-gf0bglm0	190	11	LC3C	LC3C	NNS
cord-306424-gf0bglm0	190	12	and	and	CC
cord-306424-gf0bglm0	190	13	LC3-like	lc3-like	NN
cord-306424-gf0bglm0	190	14	homologs	homolog	NNS
cord-306424-gf0bglm0	190	15	GABARAP	GABARAP	NNP
cord-306424-gf0bglm0	190	16	,	,	,
cord-306424-gf0bglm0	190	17	GABARAPL1	gabarapl1	NN
cord-306424-gf0bglm0	190	18	,	,	,
cord-306424-gf0bglm0	190	19	GABARAPL2	GABARAPL2	NNS
cord-306424-gf0bglm0	190	20	,	,	,
cord-306424-gf0bglm0	190	21	and	and	CC
cord-306424-gf0bglm0	190	22	GABARAPL3	GABARAPL3	NNP
cord-306424-gf0bglm0	190	23	.	.	.
cord-306424-gf0bglm0	191	1	We	-PRON-	PRP
cord-306424-gf0bglm0	191	2	will	will	MD
cord-306424-gf0bglm0	191	3	refer	refer	VB
cord-306424-gf0bglm0	191	4	to	to	IN
cord-306424-gf0bglm0	191	5	all	all	DT
cord-306424-gf0bglm0	191	6	of	of	IN
cord-306424-gf0bglm0	191	7	these	these	DT
cord-306424-gf0bglm0	191	8	as	as	IN
cord-306424-gf0bglm0	191	9	LC3	LC3	NNP
cord-306424-gf0bglm0	191	10	unless	unless	IN
cord-306424-gf0bglm0	191	11	stated	state	VBN
cord-306424-gf0bglm0	191	12	otherwise	otherwise	RB
cord-306424-gf0bglm0	191	13	.	.	.
cord-306424-gf0bglm0	192	1	LC3	LC3	NNP
cord-306424-gf0bglm0	192	2	was	be	VBD
cord-306424-gf0bglm0	192	3	initially	initially	RB
cord-306424-gf0bglm0	192	4	discovered	discover	VBN
cord-306424-gf0bglm0	192	5	as	as	IN
cord-306424-gf0bglm0	192	6	an	an	DT
cord-306424-gf0bglm0	192	7	essential	essential	JJ
cord-306424-gf0bglm0	192	8	protein	protein	NN
cord-306424-gf0bglm0	192	9	for	for	IN
cord-306424-gf0bglm0	192	10	autophagosome	autophagosome	NNP
cord-306424-gf0bglm0	192	11	formation	formation	NN
cord-306424-gf0bglm0	192	12	,	,	,
cord-306424-gf0bglm0	192	13	which	which	WDT
cord-306424-gf0bglm0	192	14	requires	require	VBZ
cord-306424-gf0bglm0	192	15	a	a	DT
cord-306424-gf0bglm0	192	16	covalent	covalent	JJ
cord-306424-gf0bglm0	192	17	interaction	interaction	NN
cord-306424-gf0bglm0	192	18	between	between	IN
cord-306424-gf0bglm0	192	19	cytosolic	cytosolic	JJ
cord-306424-gf0bglm0	192	20	LC3	lc3	NN
cord-306424-gf0bglm0	192	21	(	(	-LRB-
cord-306424-gf0bglm0	192	22	LC3-I	LC3-I	NNP
cord-306424-gf0bglm0	192	23	)	)	-RRB-
cord-306424-gf0bglm0	192	24	and	and	CC
cord-306424-gf0bglm0	192	25	the	the	DT
cord-306424-gf0bglm0	192	26	phospholipid	phospholipid	NN
cord-306424-gf0bglm0	192	27	phosphatidylethanolamine	phosphatidylethanolamine	NN
cord-306424-gf0bglm0	192	28	(	(	-LRB-
cord-306424-gf0bglm0	192	29	PE	PE	NNP
cord-306424-gf0bglm0	192	30	)	)	-RRB-
cord-306424-gf0bglm0	192	31	,	,	,
cord-306424-gf0bglm0	192	32	after	after	IN
cord-306424-gf0bglm0	192	33	which	which	WDT
cord-306424-gf0bglm0	192	34	LC3	LC3	NNP
cord-306424-gf0bglm0	192	35	is	be	VBZ
cord-306424-gf0bglm0	192	36	referred	refer	VBN
cord-306424-gf0bglm0	192	37	to	to	IN
cord-306424-gf0bglm0	192	38	as	as	IN
cord-306424-gf0bglm0	192	39	LC3-II	lc3-ii	NN
cord-306424-gf0bglm0	192	40	or	or	CC
cord-306424-gf0bglm0	192	41	lipidated	lipidate	VBN
cord-306424-gf0bglm0	192	42	LC3	LC3	NNP
cord-306424-gf0bglm0	192	43	[	[	-LRB-
cord-306424-gf0bglm0	192	44	126	126	CD
cord-306424-gf0bglm0	192	45	]	]	-RRB-
cord-306424-gf0bglm0	192	46	.	.	.
cord-306424-gf0bglm0	193	1	However	however	RB
cord-306424-gf0bglm0	193	2	,	,	,
cord-306424-gf0bglm0	193	3	recent	recent	JJ
cord-306424-gf0bglm0	193	4	studies	study	NNS
cord-306424-gf0bglm0	193	5	have	have	VBP
cord-306424-gf0bglm0	193	6	now	now	RB
cord-306424-gf0bglm0	193	7	revealed	reveal	VBN
cord-306424-gf0bglm0	193	8	that	that	IN
cord-306424-gf0bglm0	193	9	labeling	labeling	NN
cord-306424-gf0bglm0	193	10	of	of	IN
cord-306424-gf0bglm0	193	11	(	(	-LRB-
cord-306424-gf0bglm0	193	12	foreign	foreign	JJ
cord-306424-gf0bglm0	193	13	)	)	-RRB-
cord-306424-gf0bglm0	193	14	membrane	membrane	NN
cord-306424-gf0bglm0	193	15	compartments	compartment	NNS
cord-306424-gf0bglm0	193	16	by	by	IN
cord-306424-gf0bglm0	193	17	LC3	lc3	NN
cord-306424-gf0bglm0	193	18	conjugation	conjugation	NN
cord-306424-gf0bglm0	193	19	can	can	MD
cord-306424-gf0bglm0	193	20	also	also	RB
cord-306424-gf0bglm0	193	21	have	have	VB
cord-306424-gf0bglm0	193	22	various	various	JJ
cord-306424-gf0bglm0	193	23	autophagyunrelated	autophagyunrelate	VBN
cord-306424-gf0bglm0	193	24	consequences	consequence	NNS
cord-306424-gf0bglm0	193	25	,	,	,
cord-306424-gf0bglm0	193	26	as	as	IN
cord-306424-gf0bglm0	193	27	has	have	VBZ
cord-306424-gf0bglm0	193	28	been	be	VBN
cord-306424-gf0bglm0	193	29	reviewed	review	VBN
cord-306424-gf0bglm0	193	30	elsewhere	elsewhere	RB
cord-306424-gf0bglm0	193	31	[	[	-LRB-
cord-306424-gf0bglm0	193	32	127	127	CD
cord-306424-gf0bglm0	193	33	,	,	,
cord-306424-gf0bglm0	193	34	128	128	CD
cord-306424-gf0bglm0	193	35	]	]	-RRB-
cord-306424-gf0bglm0	193	36	.	.	.
cord-306424-gf0bglm0	194	1	Interestingly	interestingly	RB
cord-306424-gf0bglm0	194	2	,	,	,
cord-306424-gf0bglm0	194	3	multiple	multiple	JJ
cord-306424-gf0bglm0	194	4	studies	study	NNS
cord-306424-gf0bglm0	194	5	demonstrated	demonstrate	VBD
cord-306424-gf0bglm0	194	6	that	that	IN
cord-306424-gf0bglm0	194	7	labeling	labeling	NN
cord-306424-gf0bglm0	194	8	of	of	IN
cord-306424-gf0bglm0	194	9	LC3	lc3	NN
cord-306424-gf0bglm0	194	10	on	on	IN
cord-306424-gf0bglm0	194	11	PVs	pv	NNS
cord-306424-gf0bglm0	194	12	recruits	recruit	VBZ
cord-306424-gf0bglm0	194	13	IFN	IFN	NNP
cord-306424-gf0bglm0	194	14	-	-	HYPH
cord-306424-gf0bglm0	194	15	inducible	inducible	JJ
cord-306424-gf0bglm0	194	16	GTPases	gtpase	NNS
cord-306424-gf0bglm0	194	17	upon	upon	IN
cord-306424-gf0bglm0	194	18	IFN	IFN	NNP
cord-306424-gf0bglm0	194	19	-	-	HYPH
cord-306424-gf0bglm0	194	20	g	g	NN
cord-306424-gf0bglm0	194	21	expression	expression	NN
cord-306424-gf0bglm0	194	22	during	during	IN
cord-306424-gf0bglm0	194	23	T.	T.	NNP
cord-306424-gf0bglm0	194	24	gondii	gondii	NN
cord-306424-gf0bglm0	194	25	infection	infection	NN
cord-306424-gf0bglm0	194	26	,	,	,
cord-306424-gf0bglm0	194	27	resulting	result	VBG
cord-306424-gf0bglm0	194	28	in	in	IN
cord-306424-gf0bglm0	194	29	exposure	exposure	NN
cord-306424-gf0bglm0	194	30	of	of	IN
cord-306424-gf0bglm0	194	31	T.	t.	NN
cord-306424-gf0bglm0	194	32	gondii	gondii	NNP
cord-306424-gf0bglm0	194	33	to	to	IN
cord-306424-gf0bglm0	194	34	the	the	DT
cord-306424-gf0bglm0	194	35	host	host	NN
cord-306424-gf0bglm0	194	36	cell	cell	NN
cord-306424-gf0bglm0	194	37	cytosol	cytosol	NN
cord-306424-gf0bglm0	194	38	,	,	,
cord-306424-gf0bglm0	194	39	thereby	thereby	RB
cord-306424-gf0bglm0	194	40	triggering	trigger	VBG
cord-306424-gf0bglm0	194	41	anti	anti	JJ
cord-306424-gf0bglm0	194	42	-	-	JJ
cord-306424-gf0bglm0	194	43	bacterial	bacterial	JJ
cord-306424-gf0bglm0	194	44	immune	immune	JJ
cord-306424-gf0bglm0	194	45	responses	response	NNS
cord-306424-gf0bglm0	194	46	[	[	-LRB-
cord-306424-gf0bglm0	194	47	122	122	CD
cord-306424-gf0bglm0	194	48	,	,	,
cord-306424-gf0bglm0	194	49	123	123	CD
cord-306424-gf0bglm0	194	50	,	,	,
cord-306424-gf0bglm0	194	51	125	125	CD
cord-306424-gf0bglm0	194	52	]	]	-RRB-
cord-306424-gf0bglm0	194	53	.	.	.
cord-306424-gf0bglm0	195	1	Considering	consider	VBG
cord-306424-gf0bglm0	195	2	the	the	DT
cord-306424-gf0bglm0	195	3	function	function	NN
cord-306424-gf0bglm0	195	4	of	of	IN
cord-306424-gf0bglm0	195	5	LC3	LC3	NNP
cord-306424-gf0bglm0	195	6	in	in	IN
cord-306424-gf0bglm0	195	7	autophagosome	autophagosome	JJ
cord-306424-gf0bglm0	195	8	formation	formation	NN
cord-306424-gf0bglm0	195	9	,	,	,
cord-306424-gf0bglm0	195	10	Jayoung	Jayoung	NNP
cord-306424-gf0bglm0	195	11	Choi	Choi	NNP
cord-306424-gf0bglm0	195	12	and	and	CC
cord-306424-gf0bglm0	195	13	co	co	NNS
cord-306424-gf0bglm0	195	14	-	-	NNS
cord-306424-gf0bglm0	195	15	workers	worker	NNS
cord-306424-gf0bglm0	195	16	[	[	-LRB-
cord-306424-gf0bglm0	195	17	124	124	CD
cord-306424-gf0bglm0	195	18	]	]	-RRB-
cord-306424-gf0bglm0	195	19	termed	term	VBN
cord-306424-gf0bglm0	195	20	this	this	DT
cord-306424-gf0bglm0	195	21	process	process	NN
cord-306424-gf0bglm0	195	22	Targeting	target	VBG
cord-306424-gf0bglm0	195	23	by	by	IN
cord-306424-gf0bglm0	195	24	AutophaGy	AutophaGy	NNP
cord-306424-gf0bglm0	195	25	proteins	protein	NNS
cord-306424-gf0bglm0	195	26	(	(	-LRB-
cord-306424-gf0bglm0	195	27	TAG	tag	NN
cord-306424-gf0bglm0	195	28	)	)	-RRB-
cord-306424-gf0bglm0	195	29	.	.	.
cord-306424-gf0bglm0	196	1	In	in	IN
cord-306424-gf0bglm0	196	2	addition	addition	NN
cord-306424-gf0bglm0	196	3	,	,	,
cord-306424-gf0bglm0	196	4	a	a	DT
cord-306424-gf0bglm0	196	5	similar	similar	JJ
cord-306424-gf0bglm0	196	6	role	role	NN
cord-306424-gf0bglm0	196	7	was	be	VBD
cord-306424-gf0bglm0	196	8	recently	recently	RB
cord-306424-gf0bglm0	196	9	found	find	VBN
cord-306424-gf0bglm0	196	10	for	for	IN
cord-306424-gf0bglm0	196	11	ubiquitin	ubiquitin	NN
cord-306424-gf0bglm0	196	12	,	,	,
cord-306424-gf0bglm0	196	13	the	the	DT
cord-306424-gf0bglm0	196	14	versatile	versatile	JJ
cord-306424-gf0bglm0	196	15	regulator	regulator	NN
cord-306424-gf0bglm0	196	16	of	of	IN
cord-306424-gf0bglm0	196	17	numerous	numerous	JJ
cord-306424-gf0bglm0	196	18	important	important	JJ
cord-306424-gf0bglm0	196	19	cellular	cellular	JJ
cord-306424-gf0bglm0	196	20	processes	process	NNS
cord-306424-gf0bglm0	196	21	,	,	,
cord-306424-gf0bglm0	196	22	and	and	CC
cord-306424-gf0bglm0	196	23	also	also	RB
cord-306424-gf0bglm0	196	24	a	a	DT
cord-306424-gf0bglm0	196	25	well	well	RB
cord-306424-gf0bglm0	196	26	-	-	HYPH
cord-306424-gf0bglm0	196	27	known	know	VBN
cord-306424-gf0bglm0	196	28	autophagy	autophagy	NN
cord-306424-gf0bglm0	196	29	-	-	HYPH
cord-306424-gf0bglm0	196	30	related	relate	VBN
cord-306424-gf0bglm0	196	31	protein	protein	NN
cord-306424-gf0bglm0	196	32	[	[	-LRB-
cord-306424-gf0bglm0	196	33	129	129	CD
cord-306424-gf0bglm0	196	34	]	]	-RRB-
cord-306424-gf0bglm0	196	35	.	.	.
cord-306424-gf0bglm0	197	1	A	a	DT
cord-306424-gf0bglm0	197	2	study	study	NN
cord-306424-gf0bglm0	197	3	on	on	IN
cord-306424-gf0bglm0	197	4	T.	T.	NNP
cord-306424-gf0bglm0	197	5	gondii	gondii	NNP
cord-306424-gf0bglm0	197	6	and	and	CC
cord-306424-gf0bglm0	197	7	Chlamydia	Chlamydia	NNP
cord-306424-gf0bglm0	197	8	trachomatis	trachomatis	NN
cord-306424-gf0bglm0	197	9	infection	infection	NN
cord-306424-gf0bglm0	197	10	demonstrated	demonstrate	VBD
cord-306424-gf0bglm0	197	11	that	that	IN
cord-306424-gf0bglm0	197	12	PVs	pv	NNS
cord-306424-gf0bglm0	197	13	are	be	VBP
cord-306424-gf0bglm0	197	14	also	also	RB
cord-306424-gf0bglm0	197	15	recognized	recognize	VBN
cord-306424-gf0bglm0	197	16	and	and	CC
cord-306424-gf0bglm0	197	17	labeled	label	VBN
cord-306424-gf0bglm0	197	18	by	by	IN
cord-306424-gf0bglm0	197	19	the	the	DT
cord-306424-gf0bglm0	197	20	ubiquitination	ubiquitination	JJ
cord-306424-gf0bglm0	197	21	pathway	pathway	NN
cord-306424-gf0bglm0	197	22	upon	upon	IN
cord-306424-gf0bglm0	197	23	IFN	IFN	NNP
cord-306424-gf0bglm0	197	24	-	-	HYPH
cord-306424-gf0bglm0	197	25	g	g	NN
cord-306424-gf0bglm0	197	26	expression	expression	NN
cord-306424-gf0bglm0	197	27	,	,	,
cord-306424-gf0bglm0	197	28	resulting	result	VBG
cord-306424-gf0bglm0	197	29	in	in	IN
cord-306424-gf0bglm0	197	30	recruitment	recruitment	NN
cord-306424-gf0bglm0	197	31	and	and	CC
cord-306424-gf0bglm0	197	32	activation	activation	NN
cord-306424-gf0bglm0	197	33	of	of	IN
cord-306424-gf0bglm0	197	34	IFN	IFN	NNP
cord-306424-gf0bglm0	197	35	-	-	HYPH
cord-306424-gf0bglm0	197	36	inducible	inducible	JJ
cord-306424-gf0bglm0	197	37	GTPases	gtpase	NNS
cord-306424-gf0bglm0	197	38	[	[	-LRB-
cord-306424-gf0bglm0	197	39	130	130	CD
cord-306424-gf0bglm0	197	40	]	]	-RRB-
cord-306424-gf0bglm0	197	41	.	.	.
cord-306424-gf0bglm0	198	1	Importantly	importantly	RB
cord-306424-gf0bglm0	198	2	,	,	,
cord-306424-gf0bglm0	198	3	it	-PRON-	PRP
cord-306424-gf0bglm0	198	4	was	be	VBD
cord-306424-gf0bglm0	198	5	shown	show	VBN
cord-306424-gf0bglm0	198	6	that	that	IN
cord-306424-gf0bglm0	198	7	virulent	virulent	JJ
cord-306424-gf0bglm0	198	8	strains	strain	NNS
cord-306424-gf0bglm0	198	9	of	of	IN
cord-306424-gf0bglm0	198	10	T.	t.	NN
cord-306424-gf0bglm0	198	11	gondii	gondii	NNP
cord-306424-gf0bglm0	198	12	and	and	CC
cord-306424-gf0bglm0	198	13	Chlamydia	Chlamydia	NNP
cord-306424-gf0bglm0	198	14	trachomatis	trachomatis	NN
cord-306424-gf0bglm0	198	15	interfere	interfere	VBP
cord-306424-gf0bglm0	198	16	with	with	IN
cord-306424-gf0bglm0	198	17	the	the	DT
cord-306424-gf0bglm0	198	18	deposition	deposition	NN
cord-306424-gf0bglm0	198	19	of	of	IN
cord-306424-gf0bglm0	198	20	IFN	IFN	NNP
cord-306424-gf0bglm0	198	21	-	-	HYPH
cord-306424-gf0bglm0	198	22	inducible	inducible	JJ
cord-306424-gf0bglm0	198	23	GTPases	gtpase	NNS
cord-306424-gf0bglm0	198	24	on	on	IN
cord-306424-gf0bglm0	198	25	PVs	pv	NNS
cord-306424-gf0bglm0	198	26	,	,	,
cord-306424-gf0bglm0	198	27	underscoring	underscore	VBG
cord-306424-gf0bglm0	198	28	the	the	DT
cord-306424-gf0bglm0	198	29	importance	importance	NN
cord-306424-gf0bglm0	198	30	of	of	IN
cord-306424-gf0bglm0	198	31	this	this	DT
cord-306424-gf0bglm0	198	32	mechanism	mechanism	NN
cord-306424-gf0bglm0	198	33	in	in	IN
cord-306424-gf0bglm0	198	34	clearance	clearance	NN
cord-306424-gf0bglm0	198	35	of	of	IN
cord-306424-gf0bglm0	198	36	associated	associated	JJ
cord-306424-gf0bglm0	198	37	infections	infection	NNS
cord-306424-gf0bglm0	198	38	[	[	-LRB-
cord-306424-gf0bglm0	198	39	119	119	CD
cord-306424-gf0bglm0	198	40	,	,	,
cord-306424-gf0bglm0	198	41	131	131	CD
cord-306424-gf0bglm0	198	42	,	,	,
cord-306424-gf0bglm0	198	43	132	132	CD
cord-306424-gf0bglm0	198	44	]	]	-RRB-
cord-306424-gf0bglm0	198	45	.	.	.
cord-306424-gf0bglm0	199	1	Collectively	collectively	RB
cord-306424-gf0bglm0	199	2	,	,	,
cord-306424-gf0bglm0	199	3	these	these	DT
cord-306424-gf0bglm0	199	4	studies	study	NNS
cord-306424-gf0bglm0	199	5	demonstrate	demonstrate	VBP
cord-306424-gf0bglm0	199	6	the	the	DT
cord-306424-gf0bglm0	199	7	existence	existence	NN
cord-306424-gf0bglm0	199	8	of	of	IN
cord-306424-gf0bglm0	199	9	various	various	JJ
cord-306424-gf0bglm0	199	10	innate	innate	JJ
cord-306424-gf0bglm0	199	11	immune	immune	JJ
cord-306424-gf0bglm0	199	12	responses	response	NNS
cord-306424-gf0bglm0	199	13	that	that	WDT
cord-306424-gf0bglm0	199	14	result	result	VBP
cord-306424-gf0bglm0	199	15	in	in	IN
cord-306424-gf0bglm0	199	16	tagging	tagging	NN
cord-306424-gf0bglm0	199	17	and	and	CC
cord-306424-gf0bglm0	199	18	subsequent	subsequent	JJ
cord-306424-gf0bglm0	199	19	disruption	disruption	NN
cord-306424-gf0bglm0	199	20	of	of	IN
cord-306424-gf0bglm0	199	21	non	non	JJ
cord-306424-gf0bglm0	199	22	-	-	JJ
cord-306424-gf0bglm0	199	23	or	or	CC
cord-306424-gf0bglm0	199	24	aberrant	aberrant	JJ
cord-306424-gf0bglm0	199	25	-	-	HYPH
cord-306424-gf0bglm0	199	26	self	self	NN
cord-306424-gf0bglm0	199	27	membrane	membrane	NN
cord-306424-gf0bglm0	199	28	structures	structure	NNS
cord-306424-gf0bglm0	199	29	in	in	IN
cord-306424-gf0bglm0	199	30	the	the	DT
cord-306424-gf0bglm0	199	31	cell	cell	NN
cord-306424-gf0bglm0	199	32	,	,	,
cord-306424-gf0bglm0	199	33	thereby	thereby	RB
cord-306424-gf0bglm0	199	34	exposing	expose	VBG
cord-306424-gf0bglm0	199	35	PAMPs	pamp	NNS
cord-306424-gf0bglm0	199	36	and	and	CC
cord-306424-gf0bglm0	199	37	promoting	promote	VBG
cord-306424-gf0bglm0	199	38	immune	immune	JJ
cord-306424-gf0bglm0	199	39	signaling	signaling	NN
cord-306424-gf0bglm0	199	40	.	.	.
cord-306424-gf0bglm0	200	1	Importantly	importantly	RB
cord-306424-gf0bglm0	200	2	,	,	,
cord-306424-gf0bglm0	200	3	the	the	DT
cord-306424-gf0bglm0	200	4	findings	finding	NNS
cord-306424-gf0bglm0	200	5	suggest	suggest	VBP
cord-306424-gf0bglm0	200	6	that	that	IN
cord-306424-gf0bglm0	200	7	IFN	IFN	NNP
cord-306424-gf0bglm0	200	8	-	-	HYPH
cord-306424-gf0bglm0	200	9	mediated	mediate	VBN
cord-306424-gf0bglm0	200	10	membrane	membrane	NN
cord-306424-gf0bglm0	200	11	disruption	disruption	NN
cord-306424-gf0bglm0	200	12	might	may	MD
cord-306424-gf0bglm0	200	13	be	be	VB
cord-306424-gf0bglm0	200	14	a	a	DT
cord-306424-gf0bglm0	200	15	common	common	JJ
cord-306424-gf0bglm0	200	16	principle	principle	NN
cord-306424-gf0bglm0	200	17	in	in	IN
cord-306424-gf0bglm0	200	18	clearance	clearance	NN
cord-306424-gf0bglm0	200	19	of	of	IN
cord-306424-gf0bglm0	200	20	pathogens	pathogen	NNS
cord-306424-gf0bglm0	200	21	that	that	WDT
cord-306424-gf0bglm0	200	22	use	use	VBP
cord-306424-gf0bglm0	200	23	rearranged	rearrange	VBD
cord-306424-gf0bglm0	200	24	membranes	membrane	NNS
cord-306424-gf0bglm0	200	25	to	to	TO
cord-306424-gf0bglm0	200	26	support	support	VB
cord-306424-gf0bglm0	200	27	replication	replication	NN
cord-306424-gf0bglm0	200	28	and	and	CC
cord-306424-gf0bglm0	200	29	avoid	avoid	VB
cord-306424-gf0bglm0	200	30	innate	innate	JJ
cord-306424-gf0bglm0	200	31	immune	immune	JJ
cord-306424-gf0bglm0	200	32	detection	detection	NN
cord-306424-gf0bglm0	200	33	.	.	.
cord-306424-gf0bglm0	201	1	Like	like	IN
cord-306424-gf0bglm0	201	2	PVs	pv	NNS
cord-306424-gf0bglm0	201	3	,	,	,
cord-306424-gf0bglm0	201	4	ROs	ROs	NNP
cord-306424-gf0bglm0	201	5	induced	induce	VBN
cord-306424-gf0bglm0	201	6	by	by	IN
cord-306424-gf0bglm0	201	7	+	+	SYM
cord-306424-gf0bglm0	201	8	RNA	RNA	NNP
cord-306424-gf0bglm0	201	9	viruses	virus	NNS
cord-306424-gf0bglm0	201	10	are	be	VBP
cord-306424-gf0bglm0	201	11	membranous	membranous	JJ
cord-306424-gf0bglm0	201	12	compartments	compartment	NNS
cord-306424-gf0bglm0	201	13	that	that	WDT
cord-306424-gf0bglm0	201	14	constitute	constitute	VBP
cord-306424-gf0bglm0	201	15	an	an	DT
cord-306424-gf0bglm0	201	16	environment	environment	NN
cord-306424-gf0bglm0	201	17	for	for	IN
cord-306424-gf0bglm0	201	18	efficient	efficient	JJ
cord-306424-gf0bglm0	201	19	replication	replication	NN
cord-306424-gf0bglm0	201	20	,	,	,
cord-306424-gf0bglm0	201	21	simultaneously	simultaneously	RB
cord-306424-gf0bglm0	201	22	avoiding	avoid	VBG
cord-306424-gf0bglm0	201	23	immune	immune	JJ
cord-306424-gf0bglm0	201	24	detection	detection	NN
cord-306424-gf0bglm0	201	25	by	by	IN
cord-306424-gf0bglm0	201	26	the	the	DT
cord-306424-gf0bglm0	201	27	host	host	NN
cord-306424-gf0bglm0	201	28	.	.	.
cord-306424-gf0bglm0	202	1	Therefore	therefore	RB
cord-306424-gf0bglm0	202	2	,	,	,
cord-306424-gf0bglm0	202	3	similar	similar	JJ
cord-306424-gf0bglm0	202	4	mechanisms	mechanism	NNS
cord-306424-gf0bglm0	202	5	might	may	MD
cord-306424-gf0bglm0	202	6	be	be	VB
cord-306424-gf0bglm0	202	7	aimed	aim	VBN
cord-306424-gf0bglm0	202	8	towards	towards	IN
cord-306424-gf0bglm0	202	9	viral	viral	JJ
cord-306424-gf0bglm0	202	10	ROs	ro	NNS
cord-306424-gf0bglm0	202	11	.	.	.
cord-306424-gf0bglm0	203	1	The	the	DT
cord-306424-gf0bglm0	203	2	observation	observation	NN
cord-306424-gf0bglm0	203	3	that	that	IN
cord-306424-gf0bglm0	203	4	ROs	ROs	NNP
cord-306424-gf0bglm0	203	5	induced	induce	VBN
cord-306424-gf0bglm0	203	6	by	by	IN
cord-306424-gf0bglm0	203	7	various	various	JJ
cord-306424-gf0bglm0	203	8	+	+	CC
cord-306424-gf0bglm0	203	9	RNA	RNA	NNP
cord-306424-gf0bglm0	203	10	viruses	virus	NNS
cord-306424-gf0bglm0	203	11	consist	consist	VBP
cord-306424-gf0bglm0	203	12	of	of	IN
cord-306424-gf0bglm0	203	13	a	a	DT
cord-306424-gf0bglm0	203	14	double	double	JJ
cord-306424-gf0bglm0	203	15	membrane	membrane	NN
cord-306424-gf0bglm0	203	16	initially	initially	RB
cord-306424-gf0bglm0	203	17	suggested	suggest	VBD
cord-306424-gf0bglm0	203	18	a	a	DT
cord-306424-gf0bglm0	203	19	role	role	NN
cord-306424-gf0bglm0	203	20	for	for	IN
cord-306424-gf0bglm0	203	21	the	the	DT
cord-306424-gf0bglm0	203	22	autophagy	autophagy	NN
cord-306424-gf0bglm0	203	23	machinery	machinery	NN
cord-306424-gf0bglm0	203	24	in	in	IN
cord-306424-gf0bglm0	203	25	the	the	DT
cord-306424-gf0bglm0	203	26	formation	formation	NN
cord-306424-gf0bglm0	203	27	of	of	IN
cord-306424-gf0bglm0	203	28	these	these	DT
cord-306424-gf0bglm0	203	29	structures	structure	NNS
cord-306424-gf0bglm0	203	30	.	.	.
cord-306424-gf0bglm0	204	1	However	however	RB
cord-306424-gf0bglm0	204	2	,	,	,
cord-306424-gf0bglm0	204	3	only	only	RB
cord-306424-gf0bglm0	204	4	nonlipidated	nonlipidate	VBN
cord-306424-gf0bglm0	204	5	LC3	LC3	NNP
cord-306424-gf0bglm0	204	6	,	,	,
cord-306424-gf0bglm0	204	7	and	and	CC
cord-306424-gf0bglm0	204	8	not	not	RB
cord-306424-gf0bglm0	204	9	an	an	DT
cord-306424-gf0bglm0	204	10	intact	intact	JJ
cord-306424-gf0bglm0	204	11	autophagy	autophagy	NN
cord-306424-gf0bglm0	204	12	pathway	pathway	NN
cord-306424-gf0bglm0	204	13	,	,	,
cord-306424-gf0bglm0	204	14	was	be	VBD
cord-306424-gf0bglm0	204	15	found	find	VBN
cord-306424-gf0bglm0	204	16	to	to	TO
cord-306424-gf0bglm0	204	17	be	be	VB
cord-306424-gf0bglm0	204	18	essential	essential	JJ
cord-306424-gf0bglm0	204	19	for	for	IN
cord-306424-gf0bglm0	204	20	viral	viral	JJ
cord-306424-gf0bglm0	204	21	RO	ro	NN
cord-306424-gf0bglm0	204	22	formation	formation	NN
cord-306424-gf0bglm0	204	23	and	and	CC
cord-306424-gf0bglm0	204	24	viral	viral	JJ
cord-306424-gf0bglm0	204	25	replication	replication	NN
cord-306424-gf0bglm0	204	26	upon	upon	IN
cord-306424-gf0bglm0	204	27	infection	infection	NN
cord-306424-gf0bglm0	204	28	with	with	IN
cord-306424-gf0bglm0	204	29	EAV	EAV	NNP
cord-306424-gf0bglm0	204	30	and	and	CC
cord-306424-gf0bglm0	204	31	MHV	MHV	NNP
cord-306424-gf0bglm0	204	32	[	[	-LRB-
cord-306424-gf0bglm0	204	33	133	133	CD
cord-306424-gf0bglm0	204	34	,	,	,
cord-306424-gf0bglm0	204	35	134	134	CD
cord-306424-gf0bglm0	204	36	]	]	-RRB-
cord-306424-gf0bglm0	204	37	,	,	,
cord-306424-gf0bglm0	204	38	thereby	thereby	RB
cord-306424-gf0bglm0	204	39	contradicting	contradict	VBG
cord-306424-gf0bglm0	204	40	this	this	DT
cord-306424-gf0bglm0	204	41	hypothesis	hypothesis	NN
cord-306424-gf0bglm0	204	42	.	.	.
cord-306424-gf0bglm0	205	1	Interestingly	interestingly	RB
cord-306424-gf0bglm0	205	2	,	,	,
cord-306424-gf0bglm0	205	3	lipidated	lipidate	VBN
cord-306424-gf0bglm0	205	4	LC3	LC3	NNP
cord-306424-gf0bglm0	205	5	was	be	VBD
cord-306424-gf0bglm0	205	6	found	find	VBN
cord-306424-gf0bglm0	205	7	to	to	TO
cord-306424-gf0bglm0	205	8	support	support	VB
cord-306424-gf0bglm0	205	9	IFN	IFN	NNP
cord-306424-gf0bglm0	205	10	-	-	HYPH
cord-306424-gf0bglm0	205	11	g	g	NNP
cord-306424-gf0bglm0	205	12	mediated	mediate	VBD
cord-306424-gf0bglm0	205	13	protection	protection	NN
cord-306424-gf0bglm0	205	14	against	against	IN
cord-306424-gf0bglm0	205	15	murine	murine	JJ
cord-306424-gf0bglm0	205	16	norovirus	norovirus	NN
cord-306424-gf0bglm0	205	17	(	(	-LRB-
cord-306424-gf0bglm0	205	18	MNV	mnv	NN
cord-306424-gf0bglm0	205	19	)	)	-RRB-
cord-306424-gf0bglm0	205	20	infection	infection	NN
cord-306424-gf0bglm0	205	21	by	by	IN
cord-306424-gf0bglm0	205	22	autophagy	autophagy	NN
cord-306424-gf0bglm0	205	23	-	-	HYPH
cord-306424-gf0bglm0	205	24	unrelated	unrelated	JJ
cord-306424-gf0bglm0	205	25	means	mean	NNS
cord-306424-gf0bglm0	205	26	[	[	-LRB-
cord-306424-gf0bglm0	205	27	135	135	CD
cord-306424-gf0bglm0	205	28	]	]	-RRB-
cord-306424-gf0bglm0	205	29	.	.	.
cord-306424-gf0bglm0	206	1	Furthermore	furthermore	RB
cord-306424-gf0bglm0	206	2	,	,	,
cord-306424-gf0bglm0	206	3	the	the	DT
cord-306424-gf0bglm0	206	4	induction	induction	NN
cord-306424-gf0bglm0	206	5	of	of	IN
cord-306424-gf0bglm0	206	6	viral	viral	JJ
cord-306424-gf0bglm0	206	7	membranous	membranous	JJ
cord-306424-gf0bglm0	206	8	structures	structure	NNS
cord-306424-gf0bglm0	206	9	by	by	IN
cord-306424-gf0bglm0	206	10	expression	expression	NN
cord-306424-gf0bglm0	206	11	of	of	IN
cord-306424-gf0bglm0	206	12	MNV	MNV	NNP
cord-306424-gf0bglm0	206	13	nsps	nsp	NNS
cord-306424-gf0bglm0	206	14	led	lead	VBD
cord-306424-gf0bglm0	206	15	to	to	IN
cord-306424-gf0bglm0	206	16	a	a	DT
cord-306424-gf0bglm0	206	17	high	high	JJ
cord-306424-gf0bglm0	206	18	colocalization	colocalization	NN
cord-306424-gf0bglm0	206	19	between	between	IN
cord-306424-gf0bglm0	206	20	ATG16L1	ATG16L1	NNP
cord-306424-gf0bglm0	206	21	,	,	,
cord-306424-gf0bglm0	206	22	a	a	DT
cord-306424-gf0bglm0	206	23	protein	protein	NN
cord-306424-gf0bglm0	206	24	involved	involve	VBN
cord-306424-gf0bglm0	206	25	in	in	IN
cord-306424-gf0bglm0	206	26	LC3	lc3	JJ
cord-306424-gf0bglm0	206	27	conjugation	conjugation	NN
cord-306424-gf0bglm0	206	28	,	,	,
cord-306424-gf0bglm0	206	29	and	and	CC
cord-306424-gf0bglm0	206	30	the	the	DT
cord-306424-gf0bglm0	206	31	MNV	MNV	NNP
cord-306424-gf0bglm0	206	32	polymerase	polymerase	NN
cord-306424-gf0bglm0	206	33	.	.	.
cord-306424-gf0bglm0	207	1	Since	since	IN
cord-306424-gf0bglm0	207	2	ATG16L1	ATG16L1	NNS
cord-306424-gf0bglm0	207	3	determines	determine	VBZ
cord-306424-gf0bglm0	207	4	the	the	DT
cord-306424-gf0bglm0	207	5	site	site	NN
cord-306424-gf0bglm0	207	6	for	for	IN
cord-306424-gf0bglm0	207	7	LC3	lc3	JJ
cord-306424-gf0bglm0	207	8	conjugation	conjugation	NN
cord-306424-gf0bglm0	207	9	[	[	-LRB-
cord-306424-gf0bglm0	207	10	136	136	CD
cord-306424-gf0bglm0	207	11	]	]	-RRB-
cord-306424-gf0bglm0	207	12	,	,	,
cord-306424-gf0bglm0	207	13	and	and	CC
cord-306424-gf0bglm0	207	14	the	the	DT
cord-306424-gf0bglm0	207	15	MNV	mnv	NN
cord-306424-gf0bglm0	207	16	polymerase	polymerase	NN
cord-306424-gf0bglm0	207	17	is	be	VBZ
cord-306424-gf0bglm0	207	18	associated	associate	VBN
cord-306424-gf0bglm0	207	19	with	with	IN
cord-306424-gf0bglm0	207	20	ROs	ROs	NNP
cord-306424-gf0bglm0	207	21	,	,	,
cord-306424-gf0bglm0	207	22	this	this	DT
cord-306424-gf0bglm0	207	23	further	further	RB
cord-306424-gf0bglm0	207	24	supports	support	VBZ
cord-306424-gf0bglm0	207	25	the	the	DT
cord-306424-gf0bglm0	207	26	possibility	possibility	NN
cord-306424-gf0bglm0	207	27	that	that	IN
cord-306424-gf0bglm0	207	28	LC3	lc3	JJ
cord-306424-gf0bglm0	207	29	conjugation	conjugation	NN
cord-306424-gf0bglm0	207	30	occurs	occur	VBZ
cord-306424-gf0bglm0	207	31	on	on	IN
cord-306424-gf0bglm0	207	32	ROs	ROs	NNP
cord-306424-gf0bglm0	207	33	.	.	.
cord-306424-gf0bglm0	208	1	Other	other	JJ
cord-306424-gf0bglm0	208	2	supporting	support	VBG
cord-306424-gf0bglm0	208	3	in	in	IN
cord-306424-gf0bglm0	208	4	vitro	vitro	FW
cord-306424-gf0bglm0	208	5	experiments	experiment	NNS
cord-306424-gf0bglm0	208	6	show	show	VBP
cord-306424-gf0bglm0	208	7	that	that	IN
cord-306424-gf0bglm0	208	8	conditional	conditional	JJ
cord-306424-gf0bglm0	208	9	KO	KO	NNP
cord-306424-gf0bglm0	208	10	of	of	IN
cord-306424-gf0bglm0	208	11	ATG4B	ATG4B	``
cord-306424-gf0bglm0	208	12	inhibits	inhibit	VBZ
cord-306424-gf0bglm0	208	13	replication	replication	NN
cord-306424-gf0bglm0	208	14	of	of	IN
cord-306424-gf0bglm0	208	15	MNV	mnv	NN
cord-306424-gf0bglm0	208	16	and	and	CC
cord-306424-gf0bglm0	208	17	T.	t.	NN
cord-306424-gf0bglm0	208	18	gondii	gondii	NNP
cord-306424-gf0bglm0	208	19	more	more	RBR
cord-306424-gf0bglm0	208	20	effectively	effectively	RB
cord-306424-gf0bglm0	208	21	compared	compare	VBN
cord-306424-gf0bglm0	208	22	to	to	IN
cord-306424-gf0bglm0	208	23	wildtype	wildtype	NN
cord-306424-gf0bglm0	208	24	cells	cell	NNS
cord-306424-gf0bglm0	208	25	[	[	-LRB-
cord-306424-gf0bglm0	208	26	123	123	CD
cord-306424-gf0bglm0	208	27	,	,	,
cord-306424-gf0bglm0	208	28	135	135	CD
cord-306424-gf0bglm0	208	29	]	]	-RRB-
cord-306424-gf0bglm0	208	30	.	.	.
cord-306424-gf0bglm0	209	1	In	in	IN
cord-306424-gf0bglm0	209	2	contrast	contrast	NN
cord-306424-gf0bglm0	209	3	to	to	IN
cord-306424-gf0bglm0	209	4	the	the	DT
cord-306424-gf0bglm0	209	5	multiple	multiple	JJ
cord-306424-gf0bglm0	209	6	autophagins	autophagin	NNS
cord-306424-gf0bglm0	209	7	involved	involve	VBN
cord-306424-gf0bglm0	209	8	in	in	IN
cord-306424-gf0bglm0	209	9	pre	pre	JJ
cord-306424-gf0bglm0	209	10	-	-	JJ
cord-306424-gf0bglm0	209	11	processing	processing	NN
cord-306424-gf0bglm0	209	12	of	of	IN
cord-306424-gf0bglm0	209	13	LC3	lc3	NN
cord-306424-gf0bglm0	209	14	for	for	IN
cord-306424-gf0bglm0	209	15	conjugation	conjugation	NN
cord-306424-gf0bglm0	209	16	,	,	,
cord-306424-gf0bglm0	209	17	ATG4B	ATG4B	''
cord-306424-gf0bglm0	209	18	is	be	VBZ
cord-306424-gf0bglm0	209	19	the	the	DT
cord-306424-gf0bglm0	209	20	only	only	JJ
cord-306424-gf0bglm0	209	21	human	human	JJ
cord-306424-gf0bglm0	209	22	homolog	homolog	NN
cord-306424-gf0bglm0	209	23	of	of	IN
cord-306424-gf0bglm0	209	24	yeast	yeast	NN
cord-306424-gf0bglm0	209	25	ATG4	ATG4	NNP
cord-306424-gf0bglm0	209	26	that	that	WDT
cord-306424-gf0bglm0	209	27	efficiently	efficiently	RB
cord-306424-gf0bglm0	209	28	deconjugates	deconjugate	VBZ
cord-306424-gf0bglm0	209	29	LC3	LC3	NNP
cord-306424-gf0bglm0	209	30	from	from	IN
cord-306424-gf0bglm0	209	31	membranes	membrane	NNS
cord-306424-gf0bglm0	209	32	[	[	-LRB-
cord-306424-gf0bglm0	209	33	137	137	CD
cord-306424-gf0bglm0	209	34	]	]	-RRB-
cord-306424-gf0bglm0	209	35	,	,	,
cord-306424-gf0bglm0	209	36	and	and	CC
cord-306424-gf0bglm0	209	37	therefore	therefore	RB
cord-306424-gf0bglm0	209	38	plays	play	VBZ
cord-306424-gf0bglm0	209	39	a	a	DT
cord-306424-gf0bglm0	209	40	major	major	JJ
cord-306424-gf0bglm0	209	41	role	role	NN
cord-306424-gf0bglm0	209	42	in	in	IN
cord-306424-gf0bglm0	209	43	negatively	negatively	RB
cord-306424-gf0bglm0	209	44	regulating	regulate	VBG
cord-306424-gf0bglm0	209	45	the	the	DT
cord-306424-gf0bglm0	209	46	fraction	fraction	NN
cord-306424-gf0bglm0	209	47	of	of	IN
cord-306424-gf0bglm0	209	48	conjugated	conjugate	VBN
cord-306424-gf0bglm0	209	49	LC3	LC3	NNP
cord-306424-gf0bglm0	209	50	.	.	.
cord-306424-gf0bglm0	210	1	Several	several	JJ
cord-306424-gf0bglm0	210	2	groups	group	NNS
cord-306424-gf0bglm0	210	3	have	have	VBP
cord-306424-gf0bglm0	210	4	reported	report	VBN
cord-306424-gf0bglm0	210	5	enhanced	enhanced	JJ
cord-306424-gf0bglm0	210	6	conjugation	conjugation	NN
cord-306424-gf0bglm0	210	7	of	of	IN
cord-306424-gf0bglm0	210	8	LC3	lc3	NN
cord-306424-gf0bglm0	210	9	to	to	IN
cord-306424-gf0bglm0	210	10	membranes	membrane	NNS
cord-306424-gf0bglm0	210	11	during	during	IN
cord-306424-gf0bglm0	210	12	knockdown	knockdown	NN
cord-306424-gf0bglm0	210	13	of	of	IN
cord-306424-gf0bglm0	210	14	ATG4B	atg4b	CD
cord-306424-gf0bglm0	210	15	in	in	IN
cord-306424-gf0bglm0	210	16	various	various	JJ
cord-306424-gf0bglm0	210	17	cell	cell	NN
cord-306424-gf0bglm0	210	18	types	type	NNS
cord-306424-gf0bglm0	210	19	[	[	-LRB-
cord-306424-gf0bglm0	210	20	138	138	CD
cord-306424-gf0bglm0	210	21	]	]	-RRB-
cord-306424-gf0bglm0	210	22	[	[	-LRB-
cord-306424-gf0bglm0	210	23	139	139	CD
cord-306424-gf0bglm0	210	24	]	]	-RRB-
cord-306424-gf0bglm0	210	25	[	[	-LRB-
cord-306424-gf0bglm0	210	26	140	140	CD
cord-306424-gf0bglm0	210	27	]	]	-RRB-
cord-306424-gf0bglm0	210	28	[	[	-LRB-
cord-306424-gf0bglm0	210	29	141	141	CD
cord-306424-gf0bglm0	210	30	]	]	-RRB-
cord-306424-gf0bglm0	210	31	,	,	,
cord-306424-gf0bglm0	210	32	including	include	VBG
cord-306424-gf0bglm0	210	33	those	those	DT
cord-306424-gf0bglm0	210	34	used	use	VBN
cord-306424-gf0bglm0	210	35	by	by	IN
cord-306424-gf0bglm0	210	36	aforementioned	aforementioned	JJ
cord-306424-gf0bglm0	210	37	studies	study	NNS
cord-306424-gf0bglm0	210	38	[	[	-LRB-
cord-306424-gf0bglm0	210	39	123	123	CD
cord-306424-gf0bglm0	210	40	,	,	,
cord-306424-gf0bglm0	210	41	135	135	CD
cord-306424-gf0bglm0	210	42	]	]	-RRB-
cord-306424-gf0bglm0	210	43	.	.	.
cord-306424-gf0bglm0	211	1	Thus	thus	RB
cord-306424-gf0bglm0	211	2	,	,	,
cord-306424-gf0bglm0	211	3	it	-PRON-	PRP
cord-306424-gf0bglm0	211	4	is	be	VBZ
cord-306424-gf0bglm0	211	5	likely	likely	JJ
cord-306424-gf0bglm0	211	6	that	that	IN
cord-306424-gf0bglm0	211	7	increased	increase	VBN
cord-306424-gf0bglm0	211	8	lipidated	lipidate	VBN
cord-306424-gf0bglm0	211	9	LC3	LC3	NNP
cord-306424-gf0bglm0	211	10	was	be	VBD
cord-306424-gf0bglm0	211	11	present	present	JJ
cord-306424-gf0bglm0	211	12	on	on	IN
cord-306424-gf0bglm0	211	13	ROs	ro	NNS
cord-306424-gf0bglm0	211	14	and	and	CC
cord-306424-gf0bglm0	211	15	PVMs	pvm	NNS
cord-306424-gf0bglm0	211	16	during	during	IN
cord-306424-gf0bglm0	211	17	experiments	experiment	NNS
cord-306424-gf0bglm0	211	18	in	in	IN
cord-306424-gf0bglm0	211	19	ATG4B	atg4b	CD
cord-306424-gf0bglm0	211	20	-	-	HYPH
cord-306424-gf0bglm0	211	21	deficient	deficient	JJ
cord-306424-gf0bglm0	211	22	Recent	recent	JJ
cord-306424-gf0bglm0	211	23	studies	study	NNS
cord-306424-gf0bglm0	211	24	demonstrate	demonstrate	VBP
cord-306424-gf0bglm0	211	25	that	that	IN
cord-306424-gf0bglm0	211	26	LC3	LC3	NNP
cord-306424-gf0bglm0	211	27	is	be	VBZ
cord-306424-gf0bglm0	211	28	conjugated	conjugate	VBN
cord-306424-gf0bglm0	211	29	to	to	IN
cord-306424-gf0bglm0	211	30	the	the	DT
cord-306424-gf0bglm0	211	31	PVM	PVM	NNP
cord-306424-gf0bglm0	211	32	by	by	IN
cord-306424-gf0bglm0	211	33	the	the	DT
cord-306424-gf0bglm0	211	34	LC3	lc3	JJ
cord-306424-gf0bglm0	211	35	conjugation	conjugation	NN
cord-306424-gf0bglm0	211	36	system	system	NN
cord-306424-gf0bglm0	211	37	,	,	,
cord-306424-gf0bglm0	211	38	leading	lead	VBG
cord-306424-gf0bglm0	211	39	to	to	IN
cord-306424-gf0bglm0	211	40	recruitment	recruitment	NN
cord-306424-gf0bglm0	211	41	of	of	IN
cord-306424-gf0bglm0	211	42	IFN	IFN	NNP
cord-306424-gf0bglm0	211	43	-	-	HYPH
cord-306424-gf0bglm0	211	44	g	g	NN
cord-306424-gf0bglm0	211	45	inducible	inducible	JJ
cord-306424-gf0bglm0	211	46	GTPases	gtpase	NNS
cord-306424-gf0bglm0	211	47	to	to	IN
cord-306424-gf0bglm0	211	48	the	the	DT
cord-306424-gf0bglm0	211	49	PVM	PVM	NNP
cord-306424-gf0bglm0	211	50	upon	upon	IN
cord-306424-gf0bglm0	211	51	IFN	IFN	NNP
cord-306424-gf0bglm0	211	52	-	-	HYPH
cord-306424-gf0bglm0	211	53	g	g	NN
cord-306424-gf0bglm0	211	54	stimulation	stimulation	NN
cord-306424-gf0bglm0	211	55	.	.	.
cord-306424-gf0bglm0	212	1	As	as	IN
cord-306424-gf0bglm0	212	2	a	a	DT
cord-306424-gf0bglm0	212	3	consequence	consequence	NN
cord-306424-gf0bglm0	212	4	,	,	,
cord-306424-gf0bglm0	212	5	activation	activation	NN
cord-306424-gf0bglm0	212	6	of	of	IN
cord-306424-gf0bglm0	212	7	IFN	IFN	NNP
cord-306424-gf0bglm0	212	8	-	-	HYPH
cord-306424-gf0bglm0	212	9	g	g	NN
cord-306424-gf0bglm0	212	10	inducible	inducible	JJ
cord-306424-gf0bglm0	212	11	GTPases	gtpase	NNS
cord-306424-gf0bglm0	212	12	leads	lead	VBZ
cord-306424-gf0bglm0	212	13	to	to	IN
cord-306424-gf0bglm0	212	14	membrane	membrane	NN
cord-306424-gf0bglm0	212	15	disruption	disruption	NN
cord-306424-gf0bglm0	212	16	of	of	IN
cord-306424-gf0bglm0	212	17	the	the	DT
cord-306424-gf0bglm0	212	18	PVM	PVM	NNP
cord-306424-gf0bglm0	212	19	,	,	,
cord-306424-gf0bglm0	212	20	and	and	CC
cord-306424-gf0bglm0	212	21	exposure	exposure	NN
cord-306424-gf0bglm0	212	22	of	of	IN
cord-306424-gf0bglm0	212	23	T.	t.	NN
cord-306424-gf0bglm0	212	24	gondii	gondii	NNP
cord-306424-gf0bglm0	212	25	to	to	IN
cord-306424-gf0bglm0	212	26	the	the	DT
cord-306424-gf0bglm0	212	27	innate	innate	JJ
cord-306424-gf0bglm0	212	28	immune	immune	JJ
cord-306424-gf0bglm0	212	29	system	system	NN
cord-306424-gf0bglm0	212	30	.	.	.
cord-306424-gf0bglm0	213	1	cells	cell	NNS
cord-306424-gf0bglm0	213	2	,	,	,
cord-306424-gf0bglm0	213	3	thereby	thereby	RB
cord-306424-gf0bglm0	213	4	explaining	explain	VBG
cord-306424-gf0bglm0	213	5	the	the	DT
cord-306424-gf0bglm0	213	6	enhanced	enhance	VBN
cord-306424-gf0bglm0	213	7	inhibition	inhibition	NN
cord-306424-gf0bglm0	213	8	of	of	IN
cord-306424-gf0bglm0	213	9	replication	replication	NN
cord-306424-gf0bglm0	213	10	.	.	.
cord-306424-gf0bglm0	214	1	Interestingly	interestingly	RB
cord-306424-gf0bglm0	214	2	,	,	,
cord-306424-gf0bglm0	214	3	findings	finding	NNS
cord-306424-gf0bglm0	214	4	in	in	IN
cord-306424-gf0bglm0	214	5	other	other	JJ
cord-306424-gf0bglm0	214	6	studies	study	NNS
cord-306424-gf0bglm0	214	7	are	be	VBP
cord-306424-gf0bglm0	214	8	contradictory	contradictory	JJ
cord-306424-gf0bglm0	214	9	in	in	IN
cord-306424-gf0bglm0	214	10	the	the	DT
cord-306424-gf0bglm0	214	11	sense	sense	NN
cord-306424-gf0bglm0	214	12	that	that	IN
cord-306424-gf0bglm0	214	13	only	only	RB
cord-306424-gf0bglm0	214	14	LC3-I	LC3-I	NNP
cord-306424-gf0bglm0	214	15	was	be	VBD
cord-306424-gf0bglm0	214	16	observed	observe	VBN
cord-306424-gf0bglm0	214	17	on	on	IN
cord-306424-gf0bglm0	214	18	ROs	ro	NNS
cord-306424-gf0bglm0	214	19	of	of	IN
cord-306424-gf0bglm0	214	20	MNV	MNV	NNP
cord-306424-gf0bglm0	214	21	,	,	,
cord-306424-gf0bglm0	214	22	EAV	EAV	NNP
cord-306424-gf0bglm0	214	23	,	,	,
cord-306424-gf0bglm0	214	24	and	and	CC
cord-306424-gf0bglm0	214	25	MHVinfected	mhvinfecte	VBN
cord-306424-gf0bglm0	214	26	cells	cell	NNS
cord-306424-gf0bglm0	214	27	[	[	-LRB-
cord-306424-gf0bglm0	214	28	133	133	CD
cord-306424-gf0bglm0	214	29	]	]	-RRB-
cord-306424-gf0bglm0	214	30	[	[	-LRB-
cord-306424-gf0bglm0	214	31	134	134	CD
cord-306424-gf0bglm0	214	32	]	]	-RRB-
cord-306424-gf0bglm0	214	33	[	[	-LRB-
cord-306424-gf0bglm0	214	34	135	135	CD
cord-306424-gf0bglm0	214	35	]	]	-RRB-
cord-306424-gf0bglm0	214	36	.	.	.
cord-306424-gf0bglm0	215	1	On	on	IN
cord-306424-gf0bglm0	215	2	this	this	DT
cord-306424-gf0bglm0	215	3	note	note	NN
cord-306424-gf0bglm0	215	4	,	,	,
cord-306424-gf0bglm0	215	5	it	-PRON-	PRP
cord-306424-gf0bglm0	215	6	is	be	VBZ
cord-306424-gf0bglm0	215	7	worth	worth	JJ
cord-306424-gf0bglm0	215	8	mentioning	mention	VBG
cord-306424-gf0bglm0	215	9	that	that	IN
cord-306424-gf0bglm0	215	10	LC3-I	LC3-I	NNP
cord-306424-gf0bglm0	215	11	does	do	VBZ
cord-306424-gf0bglm0	215	12	not	not	RB
cord-306424-gf0bglm0	215	13	support	support	VB
cord-306424-gf0bglm0	215	14	IFN	IFN	NNP
cord-306424-gf0bglm0	215	15	-	-	HYPH
cord-306424-gf0bglm0	215	16	g	g	NNP
cord-306424-gf0bglm0	215	17	mediated	mediate	VBN
cord-306424-gf0bglm0	215	18	inhibition	inhibition	NN
cord-306424-gf0bglm0	215	19	of	of	IN
cord-306424-gf0bglm0	215	20	viral	viral	JJ
cord-306424-gf0bglm0	215	21	replication	replication	NN
cord-306424-gf0bglm0	215	22	,	,	,
cord-306424-gf0bglm0	215	23	as	as	IN
cord-306424-gf0bglm0	215	24	IFN	IFN	NNP
cord-306424-gf0bglm0	215	25	-	-	HYPH
cord-306424-gf0bglm0	215	26	g	g	NNP
cord-306424-gf0bglm0	215	27	mediated	mediate	VBN
cord-306424-gf0bglm0	215	28	inhibition	inhibition	NN
cord-306424-gf0bglm0	215	29	of	of	IN
cord-306424-gf0bglm0	215	30	MNV	mnv	NN
cord-306424-gf0bglm0	215	31	-	-	HYPH
cord-306424-gf0bglm0	215	32	infected	infect	VBN
cord-306424-gf0bglm0	215	33	cells	cell	NNS
cord-306424-gf0bglm0	215	34	does	do	VBZ
cord-306424-gf0bglm0	215	35	not	not	RB
cord-306424-gf0bglm0	215	36	occur	occur	VB
cord-306424-gf0bglm0	215	37	in	in	IN
cord-306424-gf0bglm0	215	38	the	the	DT
cord-306424-gf0bglm0	215	39	case	case	NN
cord-306424-gf0bglm0	215	40	of	of	IN
cord-306424-gf0bglm0	215	41	ATG7	ATG7	NNP
cord-306424-gf0bglm0	215	42	deficiency	deficiency	NN
cord-306424-gf0bglm0	215	43	,	,	,
cord-306424-gf0bglm0	215	44	one	one	CD
cord-306424-gf0bglm0	215	45	of	of	IN
cord-306424-gf0bglm0	215	46	the	the	DT
cord-306424-gf0bglm0	215	47	proteins	protein	NNS
cord-306424-gf0bglm0	215	48	responsible	responsible	JJ
cord-306424-gf0bglm0	215	49	for	for	IN
cord-306424-gf0bglm0	215	50	LC3	lc3	JJ
cord-306424-gf0bglm0	215	51	conjugation	conjugation	NN
cord-306424-gf0bglm0	215	52	[	[	-LRB-
cord-306424-gf0bglm0	215	53	135	135	CD
cord-306424-gf0bglm0	215	54	]	]	-RRB-
cord-306424-gf0bglm0	215	55	.	.	.
cord-306424-gf0bglm0	216	1	In	in	IN
cord-306424-gf0bglm0	216	2	conclusion	conclusion	NN
cord-306424-gf0bglm0	216	3	,	,	,
cord-306424-gf0bglm0	216	4	although	although	IN
cord-306424-gf0bglm0	216	5	there	there	EX
cord-306424-gf0bglm0	216	6	is	be	VBZ
cord-306424-gf0bglm0	216	7	no	no	DT
cord-306424-gf0bglm0	216	8	unequivocal	unequivocal	JJ
cord-306424-gf0bglm0	216	9	evidence	evidence	NN
cord-306424-gf0bglm0	216	10	regarding	regard	VBG
cord-306424-gf0bglm0	216	11	the	the	DT
cord-306424-gf0bglm0	216	12	presence	presence	NN
cord-306424-gf0bglm0	216	13	of	of	IN
cord-306424-gf0bglm0	216	14	conjugated	conjugate	VBN
cord-306424-gf0bglm0	216	15	LC3	lc3	NN
cord-306424-gf0bglm0	216	16	on	on	IN
cord-306424-gf0bglm0	216	17	+	+	CD
cord-306424-gf0bglm0	217	1	RNA	RNA	NNP
cord-306424-gf0bglm0	217	2	virus	virus	NN
cord-306424-gf0bglm0	217	3	induced	induce	VBN
cord-306424-gf0bglm0	217	4	ROs	ROs	NNP
cord-306424-gf0bglm0	217	5	,	,	,
cord-306424-gf0bglm0	217	6	the	the	DT
cord-306424-gf0bglm0	217	7	studies	study	NNS
cord-306424-gf0bglm0	217	8	described	describe	VBN
cord-306424-gf0bglm0	217	9	above	above	IN
cord-306424-gf0bglm0	217	10	provoke	provoke	VB
cord-306424-gf0bglm0	217	11	the	the	DT
cord-306424-gf0bglm0	217	12	hypothesis	hypothesis	NN
cord-306424-gf0bglm0	217	13	that	that	IN
cord-306424-gf0bglm0	217	14	membrane	membrane	NN
cord-306424-gf0bglm0	217	15	disruption	disruption	NN
cord-306424-gf0bglm0	217	16	of	of	IN
cord-306424-gf0bglm0	217	17	viral	viral	JJ
cord-306424-gf0bglm0	217	18	ROs	ro	NNS
cord-306424-gf0bglm0	217	19	mediated	mediate	VBN
cord-306424-gf0bglm0	217	20	by	by	IN
cord-306424-gf0bglm0	217	21	IFN	IFN	NNP
cord-306424-gf0bglm0	217	22	-	-	HYPH
cord-306424-gf0bglm0	217	23	g	g	NN
cord-306424-gf0bglm0	217	24	inducible	inducible	JJ
cord-306424-gf0bglm0	217	25	GTPases	gtpase	NNS
cord-306424-gf0bglm0	217	26	may	may	MD
cord-306424-gf0bglm0	217	27	be	be	VB
cord-306424-gf0bglm0	217	28	part	part	NN
cord-306424-gf0bglm0	217	29	of	of	IN
cord-306424-gf0bglm0	217	30	the	the	DT
cord-306424-gf0bglm0	217	31	innate	innate	JJ
cord-306424-gf0bglm0	217	32	immune	immune	JJ
cord-306424-gf0bglm0	217	33	response	response	NN
cord-306424-gf0bglm0	217	34	against	against	IN
cord-306424-gf0bglm0	217	35	+	+	CC
cord-306424-gf0bglm0	217	36	RNA	RNA	NNP
cord-306424-gf0bglm0	217	37	viruses	virus	NNS
cord-306424-gf0bglm0	217	38	(	(	-LRB-
cord-306424-gf0bglm0	217	39	Figure	figure	NN
cord-306424-gf0bglm0	217	40	3	3	CD
cord-306424-gf0bglm0	217	41	)	)	-RRB-
cord-306424-gf0bglm0	217	42	.	.	.
cord-306424-gf0bglm0	218	1	Interestingly	interestingly	RB
cord-306424-gf0bglm0	218	2	,	,	,
cord-306424-gf0bglm0	218	3	current	current	JJ
cord-306424-gf0bglm0	218	4	knowledge	knowledge	NN
cord-306424-gf0bglm0	218	5	of	of	IN
cord-306424-gf0bglm0	218	6	IFN	IFN	NNP
cord-306424-gf0bglm0	218	7	-	-	HYPH
cord-306424-gf0bglm0	218	8	inducible	inducible	JJ
cord-306424-gf0bglm0	218	9	GTPases	gtpase	NNS
cord-306424-gf0bglm0	218	10	suggests	suggest	VBZ
cord-306424-gf0bglm0	218	11	that	that	IN
cord-306424-gf0bglm0	218	12	membrane	membrane	NN
cord-306424-gf0bglm0	218	13	disruption	disruption	NN
cord-306424-gf0bglm0	218	14	of	of	IN
cord-306424-gf0bglm0	218	15	ROs	ro	NNS
cord-306424-gf0bglm0	218	16	by	by	IN
cord-306424-gf0bglm0	218	17	IFN	IFN	NNP
cord-306424-gf0bglm0	218	18	-	-	HYPH
cord-306424-gf0bglm0	218	19	g	g	NN
cord-306424-gf0bglm0	218	20	inducible	inducible	JJ
cord-306424-gf0bglm0	218	21	GTPases	gtpase	NNS
cord-306424-gf0bglm0	218	22	might	may	MD
cord-306424-gf0bglm0	218	23	be	be	VB
cord-306424-gf0bglm0	218	24	part	part	NN
cord-306424-gf0bglm0	218	25	of	of	IN
cord-306424-gf0bglm0	218	26	a	a	DT
cord-306424-gf0bglm0	218	27	common	common	JJ
cord-306424-gf0bglm0	218	28	antiviral	antiviral	JJ
cord-306424-gf0bglm0	218	29	mechanism	mechanism	NN
cord-306424-gf0bglm0	218	30	that	that	WDT
cord-306424-gf0bglm0	218	31	utilizes	utilize	VBZ
cord-306424-gf0bglm0	218	32	IFN	IFN	NNP
cord-306424-gf0bglm0	218	33	-	-	HYPH
cord-306424-gf0bglm0	218	34	inducible	inducible	JJ
cord-306424-gf0bglm0	218	35	GTPases	gtpase	NNS
cord-306424-gf0bglm0	218	36	to	to	TO
cord-306424-gf0bglm0	218	37	combat	combat	VB
cord-306424-gf0bglm0	218	38	viral	viral	JJ
cord-306424-gf0bglm0	218	39	infection	infection	NN
cord-306424-gf0bglm0	218	40	.	.	.
cord-306424-gf0bglm0	219	1	Aside	aside	RB
cord-306424-gf0bglm0	219	2	from	from	IN
cord-306424-gf0bglm0	219	3	IRGs	irg	NNS
cord-306424-gf0bglm0	219	4	and	and	CC
cord-306424-gf0bglm0	219	5	GBPs	gbp	NNS
cord-306424-gf0bglm0	219	6	,	,	,
cord-306424-gf0bglm0	219	7	other	other	JJ
cord-306424-gf0bglm0	219	8	families	family	NNS
cord-306424-gf0bglm0	219	9	of	of	IN
cord-306424-gf0bglm0	219	10	dynamin	dynamin	NN
cord-306424-gf0bglm0	219	11	-	-	HYPH
cord-306424-gf0bglm0	219	12	like	like	JJ
cord-306424-gf0bglm0	219	13	IFN	IFN	NNP
cord-306424-gf0bglm0	219	14	-	-	HYPH
cord-306424-gf0bglm0	219	15	inducible	inducible	JJ
cord-306424-gf0bglm0	219	16	GTPases	gtpase	NNS
cord-306424-gf0bglm0	219	17	exist	exist	VBP
cord-306424-gf0bglm0	219	18	,	,	,
cord-306424-gf0bglm0	219	19	such	such	JJ
cord-306424-gf0bglm0	219	20	as	as	IN
cord-306424-gf0bglm0	219	21	myxovirus	myxovirus	NNP
cord-306424-gf0bglm0	219	22	resistance	resistance	NN
cord-306424-gf0bglm0	219	23	proteins	protein	NNS
cord-306424-gf0bglm0	219	24	(	(	-LRB-
cord-306424-gf0bglm0	219	25	Mx	Mx	NNP
cord-306424-gf0bglm0	219	26	)	)	-RRB-
cord-306424-gf0bglm0	219	27	and	and	CC
cord-306424-gf0bglm0	219	28	the	the	DT
cord-306424-gf0bglm0	219	29	very	very	RB
cord-306424-gf0bglm0	219	30	large	large	JJ
cord-306424-gf0bglm0	219	31	IFN	IFN	NNP
cord-306424-gf0bglm0	219	32	-	-	HYPH
cord-306424-gf0bglm0	219	33	inducible	inducible	JJ
cord-306424-gf0bglm0	219	34	GTPases	gtpase	NNS
cord-306424-gf0bglm0	219	35	(	(	-LRB-
cord-306424-gf0bglm0	219	36	VLIGs	vlig	NNS
cord-306424-gf0bglm0	219	37	)	)	-RRB-
cord-306424-gf0bglm0	219	38	[	[	-LRB-
cord-306424-gf0bglm0	219	39	116	116	CD
cord-306424-gf0bglm0	219	40	]	]	-RRB-
cord-306424-gf0bglm0	219	41	.	.	.
cord-306424-gf0bglm0	220	1	These	these	DT
cord-306424-gf0bglm0	220	2	enzymes	enzyme	NNS
cord-306424-gf0bglm0	220	3	are	be	VBP
cord-306424-gf0bglm0	220	4	also	also	RB
cord-306424-gf0bglm0	220	5	known	know	VBN
cord-306424-gf0bglm0	220	6	to	to	TO
cord-306424-gf0bglm0	220	7	have	have	VB
cord-306424-gf0bglm0	220	8	antiviral	antiviral	JJ
cord-306424-gf0bglm0	220	9	properties	property	NNS
cord-306424-gf0bglm0	220	10	against	against	IN
cord-306424-gf0bglm0	220	11	a	a	DT
cord-306424-gf0bglm0	220	12	variety	variety	NN
cord-306424-gf0bglm0	220	13	of	of	IN
cord-306424-gf0bglm0	220	14	viruses	virus	NNS
cord-306424-gf0bglm0	220	15	(	(	-LRB-
cord-306424-gf0bglm0	220	16	reviewed	review	VBN
cord-306424-gf0bglm0	220	17	in	in	IN
cord-306424-gf0bglm0	220	18	[	[	-LRB-
cord-306424-gf0bglm0	220	19	116	116	CD
cord-306424-gf0bglm0	220	20	]	]	-RRB-
cord-306424-gf0bglm0	220	21	)	)	-RRB-
cord-306424-gf0bglm0	220	22	.	.	.
cord-306424-gf0bglm0	221	1	For	for	IN
cord-306424-gf0bglm0	221	2	example	example	NN
cord-306424-gf0bglm0	221	3	,	,	,
cord-306424-gf0bglm0	221	4	the	the	DT
cord-306424-gf0bglm0	221	5	protective	protective	JJ
cord-306424-gf0bglm0	221	6	role	role	NN
cord-306424-gf0bglm0	221	7	of	of	IN
cord-306424-gf0bglm0	221	8	Mx	Mx	NNP
cord-306424-gf0bglm0	221	9	proteins	protein	NNS
cord-306424-gf0bglm0	221	10	has	have	VBZ
cord-306424-gf0bglm0	221	11	been	be	VBN
cord-306424-gf0bglm0	221	12	demonstrated	demonstrate	VBN
cord-306424-gf0bglm0	221	13	for	for	IN
cord-306424-gf0bglm0	221	14	orthomyxoviruses	orthomyxovirus	NNS
cord-306424-gf0bglm0	221	15	such	such	JJ
cord-306424-gf0bglm0	221	16	as	as	IN
cord-306424-gf0bglm0	221	17	influenza	influenza	NN
cord-306424-gf0bglm0	221	18	,	,	,
cord-306424-gf0bglm0	221	19	lentiviruses	lentiviruse	NNS
cord-306424-gf0bglm0	221	20	such	such	JJ
cord-306424-gf0bglm0	221	21	as	as	IN
cord-306424-gf0bglm0	221	22	human	human	JJ
cord-306424-gf0bglm0	221	23	immunodeficiency	immunodeficiency	NN
cord-306424-gf0bglm0	221	24	virus	virus	NN
cord-306424-gf0bglm0	221	25	(	(	-LRB-
cord-306424-gf0bglm0	221	26	HIV	HIV	NNP
cord-306424-gf0bglm0	221	27	)	)	-RRB-
cord-306424-gf0bglm0	221	28	1	1	CD
cord-306424-gf0bglm0	221	29	,	,	,
cord-306424-gf0bglm0	221	30	and	and	CC
cord-306424-gf0bglm0	221	31	,	,	,
cord-306424-gf0bglm0	221	32	interestingly	interestingly	RB
cord-306424-gf0bglm0	221	33	,	,	,
cord-306424-gf0bglm0	221	34	several	several	JJ
cord-306424-gf0bglm0	221	35	+	+	SYM
cord-306424-gf0bglm0	221	36	RNA	rna	NN
cord-306424-gf0bglm0	221	37	viruses	virus	NNS
cord-306424-gf0bglm0	221	38	belonging	belong	VBG
cord-306424-gf0bglm0	221	39	to	to	IN
cord-306424-gf0bglm0	221	40	the	the	DT
cord-306424-gf0bglm0	221	41	picornaviridae	picornaviridae	NN
cord-306424-gf0bglm0	221	42	and	and	CC
cord-306424-gf0bglm0	221	43	togaviridae	togaviridae	NNP
cord-306424-gf0bglm0	221	44	[	[	-LRB-
cord-306424-gf0bglm0	221	45	116	116	CD
cord-306424-gf0bglm0	221	46	]	]	-RRB-
cord-306424-gf0bglm0	221	47	.	.	.
cord-306424-gf0bglm0	222	1	Moreover	moreover	RB
cord-306424-gf0bglm0	222	2	,	,	,
cord-306424-gf0bglm0	222	3	based	base	VBN
cord-306424-gf0bglm0	222	4	on	on	IN
cord-306424-gf0bglm0	222	5	evolutionary	evolutionary	JJ
cord-306424-gf0bglm0	222	6	studies	study	NNS
cord-306424-gf0bglm0	222	7	,	,	,
cord-306424-gf0bglm0	222	8	it	-PRON-	PRP
cord-306424-gf0bglm0	222	9	was	be	VBD
cord-306424-gf0bglm0	222	10	recently	recently	RB
cord-306424-gf0bglm0	222	11	suggested	suggest	VBN
cord-306424-gf0bglm0	222	12	that	that	IN
cord-306424-gf0bglm0	222	13	Mx	Mx	NNP
cord-306424-gf0bglm0	222	14	proteins	protein	NNS
cord-306424-gf0bglm0	222	15	mediate	mediate	VBP
cord-306424-gf0bglm0	222	16	protection	protection	NN
cord-306424-gf0bglm0	222	17	against	against	IN
cord-306424-gf0bglm0	222	18	even	even	RB
cord-306424-gf0bglm0	222	19	a	a	DT
cord-306424-gf0bglm0	222	20	wider	wide	JJR
cord-306424-gf0bglm0	222	21	variety	variety	NN
cord-306424-gf0bglm0	222	22	of	of	IN
cord-306424-gf0bglm0	222	23	viruses	virus	NNS
cord-306424-gf0bglm0	222	24	[	[	-LRB-
cord-306424-gf0bglm0	222	25	142	142	CD
cord-306424-gf0bglm0	222	26	]	]	-RRB-
cord-306424-gf0bglm0	222	27	.	.	.
cord-306424-gf0bglm0	223	1	In	in	IN
cord-306424-gf0bglm0	223	2	contrast	contrast	NN
cord-306424-gf0bglm0	223	3	to	to	IN
cord-306424-gf0bglm0	223	4	IFN	IFN	NNP
cord-306424-gf0bglm0	223	5	-	-	HYPH
cord-306424-gf0bglm0	223	6	g	g	NNP
cord-306424-gf0bglm0	223	7	inducible	inducible	JJ
cord-306424-gf0bglm0	223	8	IRGs	irg	NNS
cord-306424-gf0bglm0	223	9	and	and	CC
cord-306424-gf0bglm0	223	10	GBPs	gbp	NNS
cord-306424-gf0bglm0	223	11	,	,	,
cord-306424-gf0bglm0	223	12	expression	expression	NN
cord-306424-gf0bglm0	223	13	of	of	IN
cord-306424-gf0bglm0	223	14	Mx	Mx	NNP
cord-306424-gf0bglm0	223	15	proteins	protein	NNS
cord-306424-gf0bglm0	223	16	is	be	VBZ
cord-306424-gf0bglm0	223	17	induced	induce	VBN
cord-306424-gf0bglm0	223	18	by	by	IN
cord-306424-gf0bglm0	223	19	IFNs	ifns	NN
cord-306424-gf0bglm0	223	20	type	type	NN
cord-306424-gf0bglm0	223	21	I	I	NNP
cord-306424-gf0bglm0	223	22	and	and	CC
cord-306424-gf0bglm0	223	23	III	III	NNP
cord-306424-gf0bglm0	223	24	,	,	,
cord-306424-gf0bglm0	223	25	implying	imply	VBG
cord-306424-gf0bglm0	223	26	that	that	IN
cord-306424-gf0bglm0	223	27	all	all	DT
cord-306424-gf0bglm0	223	28	IFN	IFN	NNP
cord-306424-gf0bglm0	223	29	types	type	NNS
cord-306424-gf0bglm0	223	30	are	be	VBP
cord-306424-gf0bglm0	223	31	capable	capable	JJ
cord-306424-gf0bglm0	223	32	of	of	IN
cord-306424-gf0bglm0	223	33	inducing	induce	VBG
cord-306424-gf0bglm0	223	34	IFN	IFN	NNP
cord-306424-gf0bglm0	223	35	-	-	HYPH
cord-306424-gf0bglm0	223	36	inducible	inducible	JJ
cord-306424-gf0bglm0	223	37	GTPases	gtpase	NNS
cord-306424-gf0bglm0	223	38	[	[	-LRB-
cord-306424-gf0bglm0	223	39	116	116	CD
cord-306424-gf0bglm0	223	40	]	]	-RRB-
cord-306424-gf0bglm0	223	41	.	.	.
cord-306424-gf0bglm0	224	1	Therefore	therefore	RB
cord-306424-gf0bglm0	224	2	,	,	,
cord-306424-gf0bglm0	224	3	all	all	DT
cord-306424-gf0bglm0	224	4	cell	cell	NN
cord-306424-gf0bglm0	224	5	types	type	NNS
cord-306424-gf0bglm0	224	6	known	know	VBN
cord-306424-gf0bglm0	224	7	to	to	TO
cord-306424-gf0bglm0	224	8	respond	respond	VB
cord-306424-gf0bglm0	224	9	to	to	IN
cord-306424-gf0bglm0	224	10	IFNs	ifn	NNS
cord-306424-gf0bglm0	224	11	could	could	MD
cord-306424-gf0bglm0	224	12	theoretically	theoretically	RB
cord-306424-gf0bglm0	224	13	induce	induce	VB
cord-306424-gf0bglm0	224	14	a	a	DT
cord-306424-gf0bglm0	224	15	variety	variety	NN
cord-306424-gf0bglm0	224	16	of	of	IN
cord-306424-gf0bglm0	224	17	IFN	IFN	NNP
cord-306424-gf0bglm0	224	18	-	-	HYPH
cord-306424-gf0bglm0	224	19	inducible	inducible	JJ
cord-306424-gf0bglm0	224	20	GTPases	gtpase	NNS
cord-306424-gf0bglm0	224	21	in	in	IN
cord-306424-gf0bglm0	224	22	response	response	NN
cord-306424-gf0bglm0	224	23	to	to	IN
cord-306424-gf0bglm0	224	24	viral	viral	JJ
cord-306424-gf0bglm0	224	25	infection	infection	NN
cord-306424-gf0bglm0	224	26	.	.	.
cord-306424-gf0bglm0	225	1	In	in	IN
cord-306424-gf0bglm0	225	2	the	the	DT
cord-306424-gf0bglm0	225	3	case	case	NN
cord-306424-gf0bglm0	225	4	of	of	IN
cord-306424-gf0bglm0	225	5	+	+	``
cord-306424-gf0bglm0	225	6	RNA	RNA	NNP
cord-306424-gf0bglm0	225	7	viruses	virus	NNS
cord-306424-gf0bglm0	225	8	,	,	,
cord-306424-gf0bglm0	225	9	it	-PRON-	PRP
cord-306424-gf0bglm0	225	10	is	be	VBZ
cord-306424-gf0bglm0	225	11	intriguing	intriguing	JJ
cord-306424-gf0bglm0	225	12	that	that	IN
cord-306424-gf0bglm0	225	13	multiple	multiple	JJ
cord-306424-gf0bglm0	225	14	studies	study	NNS
cord-306424-gf0bglm0	225	15	demonstrated	demonstrate	VBD
cord-306424-gf0bglm0	225	16	how	how	WRB
cord-306424-gf0bglm0	225	17	MxB	MxB	NNP
cord-306424-gf0bglm0	225	18	suppresses	suppress	VBZ
cord-306424-gf0bglm0	225	19	replication	replication	NN
cord-306424-gf0bglm0	225	20	of	of	IN
cord-306424-gf0bglm0	225	21	HIV-1	HIV-1	NNP
cord-306424-gf0bglm0	225	22	by	by	IN
cord-306424-gf0bglm0	225	23	targeting	target	VBG
cord-306424-gf0bglm0	225	24	the	the	DT
cord-306424-gf0bglm0	225	25	viral	viral	JJ
cord-306424-gf0bglm0	225	26	capsid	capsid	NN
cord-306424-gf0bglm0	225	27	protein	protein	NN
cord-306424-gf0bglm0	225	28	[	[	-LRB-
cord-306424-gf0bglm0	225	29	143	143	CD
cord-306424-gf0bglm0	225	30	]	]	-RRB-
cord-306424-gf0bglm0	225	31	[	[	-LRB-
cord-306424-gf0bglm0	225	32	144	144	CD
cord-306424-gf0bglm0	225	33	]	]	-RRB-
cord-306424-gf0bglm0	225	34	[	[	-LRB-
cord-306424-gf0bglm0	225	35	145	145	CD
cord-306424-gf0bglm0	225	36	]	]	-RRB-
cord-306424-gf0bglm0	225	37	,	,	,
cord-306424-gf0bglm0	225	38	given	give	VBN
cord-306424-gf0bglm0	225	39	the	the	DT
cord-306424-gf0bglm0	225	40	parallels	parallel	NNS
cord-306424-gf0bglm0	225	41	between	between	IN
cord-306424-gf0bglm0	225	42	retroviral	retroviral	JJ
cord-306424-gf0bglm0	225	43	capsids	capsid	NNS
cord-306424-gf0bglm0	225	44	and	and	CC
cord-306424-gf0bglm0	225	45	+	+	SYM
cord-306424-gf0bglm0	225	46	RNA	RNA	NNP
cord-306424-gf0bglm0	225	47	virus	virus	NN
cord-306424-gf0bglm0	225	48	ROs	ROs	NNP
cord-306424-gf0bglm0	225	49	[	[	-LRB-
cord-306424-gf0bglm0	225	50	146	146	CD
cord-306424-gf0bglm0	225	51	]	]	-RRB-
cord-306424-gf0bglm0	225	52	.	.	.
cord-306424-gf0bglm0	226	1	In	in	IN
cord-306424-gf0bglm0	226	2	conclusion	conclusion	NN
cord-306424-gf0bglm0	226	3	,	,	,
cord-306424-gf0bglm0	226	4	these	these	DT
cord-306424-gf0bglm0	226	5	findings	finding	NNS
cord-306424-gf0bglm0	226	6	again	again	RB
cord-306424-gf0bglm0	226	7	suggest	suggest	VBP
cord-306424-gf0bglm0	226	8	a	a	DT
cord-306424-gf0bglm0	226	9	general	general	JJ
cord-306424-gf0bglm0	226	10	function	function	NN
cord-306424-gf0bglm0	226	11	for	for	IN
cord-306424-gf0bglm0	226	12	IFN	IFN	NNP
cord-306424-gf0bglm0	226	13	-	-	HYPH
cord-306424-gf0bglm0	226	14	inducible	inducible	JJ
cord-306424-gf0bglm0	226	15	GTPase	GTPase	NNP
cord-306424-gf0bglm0	226	16	effectors	effector	NNS
cord-306424-gf0bglm0	226	17	in	in	IN
cord-306424-gf0bglm0	226	18	the	the	DT
cord-306424-gf0bglm0	226	19	targeting	targeting	NN
cord-306424-gf0bglm0	226	20	of	of	IN
cord-306424-gf0bglm0	226	21	viral	viral	JJ
cord-306424-gf0bglm0	226	22	intracellular	intracellular	JJ
cord-306424-gf0bglm0	226	23	membrane	membrane	NN
cord-306424-gf0bglm0	226	24	structures	structure	NNS
cord-306424-gf0bglm0	226	25	that	that	WDT
cord-306424-gf0bglm0	226	26	function	function	VBP
cord-306424-gf0bglm0	226	27	to	to	TO
cord-306424-gf0bglm0	226	28	shield	shield	VB
cord-306424-gf0bglm0	226	29	away	away	RP
cord-306424-gf0bglm0	226	30	viral	viral	JJ
cord-306424-gf0bglm0	226	31	components	component	NNS
cord-306424-gf0bglm0	226	32	away	away	RB
cord-306424-gf0bglm0	226	33	from	from	IN
cord-306424-gf0bglm0	226	34	the	the	DT
cord-306424-gf0bglm0	226	35	cytosol	cytosol	NN
cord-306424-gf0bglm0	226	36	.	.	.
cord-306424-gf0bglm0	227	1	Rearrangement	rearrangement	NN
cord-306424-gf0bglm0	227	2	of	of	IN
cord-306424-gf0bglm0	227	3	host	host	NN
cord-306424-gf0bglm0	227	4	membranes	membrane	NNS
cord-306424-gf0bglm0	227	5	into	into	IN
cord-306424-gf0bglm0	227	6	ROs	ROs	NNP
cord-306424-gf0bglm0	227	7	is	be	VBZ
cord-306424-gf0bglm0	227	8	considered	consider	VBN
cord-306424-gf0bglm0	227	9	a	a	DT
cord-306424-gf0bglm0	227	10	hallmark	hallmark	NN
cord-306424-gf0bglm0	227	11	of	of	IN
cord-306424-gf0bglm0	227	12	+	+	SYM
cord-306424-gf0bglm0	227	13	RNA	RNA	NNP
cord-306424-gf0bglm0	227	14	virus	virus	NN
cord-306424-gf0bglm0	227	15	infection	infection	NN
cord-306424-gf0bglm0	227	16	.	.	.
cord-306424-gf0bglm0	228	1	ROs	ro	NNS
cord-306424-gf0bglm0	228	2	are	be	VBP
cord-306424-gf0bglm0	228	3	believed	believe	VBN
cord-306424-gf0bglm0	228	4	to	to	TO
cord-306424-gf0bglm0	228	5	have	have	VB
cord-306424-gf0bglm0	228	6	at	at	IN
cord-306424-gf0bglm0	228	7	least	least	JJS
cord-306424-gf0bglm0	228	8	a	a	DT
cord-306424-gf0bglm0	228	9	dual	dual	JJ
cord-306424-gf0bglm0	228	10	role	role	NN
cord-306424-gf0bglm0	228	11	in	in	IN
cord-306424-gf0bglm0	228	12	+	+	CC
cord-306424-gf0bglm0	228	13	RNA	RNA	NNP
cord-306424-gf0bglm0	228	14	virus	virus	NN
cord-306424-gf0bglm0	228	15	infection	infection	NN
cord-306424-gf0bglm0	228	16	and	and	CC
cord-306424-gf0bglm0	228	17	innate	innate	JJ
cord-306424-gf0bglm0	228	18	immune	immune	JJ
cord-306424-gf0bglm0	228	19	evasion	evasion	NN
cord-306424-gf0bglm0	228	20	,	,	,
cord-306424-gf0bglm0	228	21	as	as	IN
cord-306424-gf0bglm0	228	22	they	-PRON-	PRP
cord-306424-gf0bglm0	228	23	facilitate	facilitate	VBP
cord-306424-gf0bglm0	228	24	efficient	efficient	JJ
cord-306424-gf0bglm0	228	25	RNA	RNA	NNP
cord-306424-gf0bglm0	228	26	replication	replication	NN
cord-306424-gf0bglm0	228	27	while	while	IN
cord-306424-gf0bglm0	228	28	shielding	shield	VBG
cord-306424-gf0bglm0	228	29	viral	viral	JJ
cord-306424-gf0bglm0	228	30	RNA	RNA	NNP
cord-306424-gf0bglm0	228	31	from	from	IN
cord-306424-gf0bglm0	228	32	the	the	DT
cord-306424-gf0bglm0	228	33	host	host	NN
cord-306424-gf0bglm0	228	34	antiviral	antiviral	JJ
cord-306424-gf0bglm0	228	35	response	response	NN
cord-306424-gf0bglm0	228	36	machinery	machinery	NN
cord-306424-gf0bglm0	228	37	.	.	.
cord-306424-gf0bglm0	229	1	As	as	IN
cord-306424-gf0bglm0	229	2	viral	viral	JJ
cord-306424-gf0bglm0	229	3	RNA	RNA	NNP
cord-306424-gf0bglm0	229	4	is	be	VBZ
cord-306424-gf0bglm0	229	5	a	a	DT
cord-306424-gf0bglm0	229	6	very	very	RB
cord-306424-gf0bglm0	229	7	potent	potent	JJ
cord-306424-gf0bglm0	229	8	inducer	inducer	NN
cord-306424-gf0bglm0	229	9	of	of	IN
cord-306424-gf0bglm0	229	10	antiviral	antiviral	JJ
cord-306424-gf0bglm0	229	11	signaling	signaling	NN
cord-306424-gf0bglm0	229	12	,	,	,
cord-306424-gf0bglm0	229	13	we	-PRON-	PRP
cord-306424-gf0bglm0	229	14	focused	focus	VBD
cord-306424-gf0bglm0	229	15	on	on	IN
cord-306424-gf0bglm0	229	16	how	how	WRB
cord-306424-gf0bglm0	229	17	both	both	CC
cord-306424-gf0bglm0	229	18	the	the	DT
cord-306424-gf0bglm0	229	19	biochemical	biochemical	JJ
cord-306424-gf0bglm0	229	20	and	and	CC
cord-306424-gf0bglm0	229	21	spatial	spatial	JJ
cord-306424-gf0bglm0	229	22	organization	organization	NN
cord-306424-gf0bglm0	229	23	allows	allow	VBZ
cord-306424-gf0bglm0	229	24	the	the	DT
cord-306424-gf0bglm0	229	25	innate	innate	JJ
cord-306424-gf0bglm0	229	26	immune	immune	JJ
cord-306424-gf0bglm0	229	27	system	system	NN
cord-306424-gf0bglm0	229	28	to	to	TO
cord-306424-gf0bglm0	229	29	convert	convert	VB
cord-306424-gf0bglm0	229	30	detection	detection	NN
cord-306424-gf0bglm0	229	31	of	of	IN
cord-306424-gf0bglm0	229	32	viral	viral	JJ
cord-306424-gf0bglm0	229	33	RNA	RNA	NNP
cord-306424-gf0bglm0	229	34	to	to	IN
cord-306424-gf0bglm0	229	35	an	an	DT
cord-306424-gf0bglm0	229	36	antiviral	antiviral	JJ
cord-306424-gf0bglm0	229	37	state	state	NN
cord-306424-gf0bglm0	229	38	.	.	.
cord-306424-gf0bglm0	230	1	In	in	IN
cord-306424-gf0bglm0	230	2	addition	addition	NN
cord-306424-gf0bglm0	230	3	,	,	,
cord-306424-gf0bglm0	230	4	we	-PRON-	PRP
cord-306424-gf0bglm0	230	5	described	describe	VBD
cord-306424-gf0bglm0	230	6	part	part	NN
cord-306424-gf0bglm0	230	7	of	of	IN
cord-306424-gf0bglm0	230	8	the	the	DT
cord-306424-gf0bglm0	230	9	divergent	divergent	JJ
cord-306424-gf0bglm0	230	10	methods	method	NNS
cord-306424-gf0bglm0	230	11	by	by	IN
cord-306424-gf0bglm0	230	12	which	which	WDT
cord-306424-gf0bglm0	230	13	+	+	CC
cord-306424-gf0bglm0	230	14	RNA	RNA	NNP
cord-306424-gf0bglm0	230	15	viruses	virus	NNS
cord-306424-gf0bglm0	230	16	impair	impair	VBP
cord-306424-gf0bglm0	230	17	antiviral	antiviral	JJ
cord-306424-gf0bglm0	230	18	signaling	signal	VBG
cord-306424-gf0bglm0	230	19	surrounding	surround	VBG
cord-306424-gf0bglm0	230	20	their	-PRON-	PRP$
cord-306424-gf0bglm0	230	21	RNA	RNA	NNP
cord-306424-gf0bglm0	230	22	replication	replication	NN
cord-306424-gf0bglm0	230	23	,	,	,
cord-306424-gf0bglm0	230	24	transcription	transcription	NN
cord-306424-gf0bglm0	230	25	,	,	,
cord-306424-gf0bglm0	230	26	and	and	CC
cord-306424-gf0bglm0	230	27	translation	translation	NN
cord-306424-gf0bglm0	230	28	in	in	IN
cord-306424-gf0bglm0	230	29	order	order	NN
cord-306424-gf0bglm0	230	30	to	to	TO
cord-306424-gf0bglm0	230	31	establish	establish	VB
cord-306424-gf0bglm0	230	32	infection	infection	NN
cord-306424-gf0bglm0	230	33	.	.	.
cord-306424-gf0bglm0	231	1	At	at	IN
cord-306424-gf0bglm0	231	2	last	last	RB
cord-306424-gf0bglm0	231	3	,	,	,
cord-306424-gf0bglm0	231	4	based	base	VBN
cord-306424-gf0bglm0	231	5	on	on	IN
cord-306424-gf0bglm0	231	6	recent	recent	JJ
cord-306424-gf0bglm0	231	7	studies	study	NNS
cord-306424-gf0bglm0	231	8	that	that	WDT
cord-306424-gf0bglm0	231	9	demonstrated	demonstrate	VBD
cord-306424-gf0bglm0	231	10	how	how	WRB
cord-306424-gf0bglm0	231	11	IFN	IFN	NNP
cord-306424-gf0bglm0	231	12	-	-	HYPH
cord-306424-gf0bglm0	231	13	g	g	NN
cord-306424-gf0bglm0	231	14	inducible	inducible	JJ
cord-306424-gf0bglm0	231	15	GTPases	gtpase	NNS
cord-306424-gf0bglm0	231	16	are	be	VBP
cord-306424-gf0bglm0	231	17	capable	capable	JJ
cord-306424-gf0bglm0	231	18	of	of	IN
cord-306424-gf0bglm0	231	19	disrupting	disrupt	VBG
cord-306424-gf0bglm0	231	20	PVs	pv	NNS
cord-306424-gf0bglm0	231	21	,	,	,
cord-306424-gf0bglm0	231	22	we	-PRON-	PRP
cord-306424-gf0bglm0	231	23	discussed	discuss	VBD
cord-306424-gf0bglm0	231	24	the	the	DT
cord-306424-gf0bglm0	231	25	possibility	possibility	NN
cord-306424-gf0bglm0	231	26	of	of	IN
cord-306424-gf0bglm0	231	27	a	a	DT
cord-306424-gf0bglm0	231	28	general	general	JJ
cord-306424-gf0bglm0	231	29	function	function	NN
cord-306424-gf0bglm0	231	30	of	of	IN
cord-306424-gf0bglm0	231	31	IFN	IFN	NNP
cord-306424-gf0bglm0	231	32	-	-	HYPH
cord-306424-gf0bglm0	231	33	inducible	inducible	JJ
cord-306424-gf0bglm0	231	34	GTPases	gtpase	NNS
cord-306424-gf0bglm0	231	35	in	in	IN
cord-306424-gf0bglm0	231	36	the	the	DT
cord-306424-gf0bglm0	231	37	targeting	targeting	NN
cord-306424-gf0bglm0	231	38	of	of	IN
cord-306424-gf0bglm0	231	39	viral	viral	JJ
cord-306424-gf0bglm0	231	40	ROs	ro	NNS
cord-306424-gf0bglm0	231	41	.	.	.
cord-306424-gf0bglm0	232	1	In	in	IN
cord-306424-gf0bglm0	232	2	summary	summary	NN
cord-306424-gf0bglm0	232	3	,	,	,
cord-306424-gf0bglm0	232	4	upon	upon	IN
cord-306424-gf0bglm0	232	5	infection	infection	NN
cord-306424-gf0bglm0	232	6	,	,	,
cord-306424-gf0bglm0	232	7	+	+	CC
cord-306424-gf0bglm0	232	8	RNA	rna	NN
cord-306424-gf0bglm0	232	9	viruses	virus	NNS
cord-306424-gf0bglm0	232	10	hamper	hamper	VBP
cord-306424-gf0bglm0	232	11	IFN	IFN	NNP
cord-306424-gf0bglm0	232	12	and	and	CC
cord-306424-gf0bglm0	232	13	ISG	ISG	NNP
cord-306424-gf0bglm0	232	14	induction	induction	NN
cord-306424-gf0bglm0	232	15	at	at	IN
cord-306424-gf0bglm0	232	16	multiple	multiple	JJ
cord-306424-gf0bglm0	232	17	levels	level	NNS
cord-306424-gf0bglm0	232	18	to	to	TO
cord-306424-gf0bglm0	232	19	decelerate	decelerate	VB
cord-306424-gf0bglm0	232	20	antiviral	antiviral	JJ
cord-306424-gf0bglm0	232	21	innate	innate	JJ
cord-306424-gf0bglm0	232	22	immune	immune	JJ
cord-306424-gf0bglm0	232	23	signaling	signaling	NN
cord-306424-gf0bglm0	232	24	.	.	.
cord-306424-gf0bglm0	233	1	In	in	IN
cord-306424-gf0bglm0	233	2	this	this	DT
cord-306424-gf0bglm0	233	3	process	process	NN
cord-306424-gf0bglm0	233	4	,	,	,
cord-306424-gf0bglm0	233	5	the	the	DT
cord-306424-gf0bglm0	233	6	formation	formation	NN
cord-306424-gf0bglm0	233	7	of	of	IN
cord-306424-gf0bglm0	233	8	ROs	ROs	NNP
cord-306424-gf0bglm0	233	9	enables	enable	VBZ
cord-306424-gf0bglm0	233	10	rapid	rapid	JJ
cord-306424-gf0bglm0	233	11	viral	viral	JJ
cord-306424-gf0bglm0	233	12	RNA	RNA	NNP
cord-306424-gf0bglm0	233	13	replication	replication	NN
cord-306424-gf0bglm0	233	14	while	while	IN
cord-306424-gf0bglm0	233	15	masking	mask	VBG
cord-306424-gf0bglm0	233	16	it	-PRON-	PRP
cord-306424-gf0bglm0	233	17	from	from	IN
cord-306424-gf0bglm0	233	18	the	the	DT
cord-306424-gf0bglm0	233	19	host	host	NN
cord-306424-gf0bglm0	233	20	.	.	.
cord-306424-gf0bglm0	234	1	However	however	RB
cord-306424-gf0bglm0	234	2	,	,	,
cord-306424-gf0bglm0	234	3	in	in	IN
cord-306424-gf0bglm0	234	4	case	case	NN
cord-306424-gf0bglm0	234	5	of	of	IN
cord-306424-gf0bglm0	234	6	sufficient	sufficient	JJ
cord-306424-gf0bglm0	234	7	activation	activation	NN
cord-306424-gf0bglm0	234	8	of	of	IN
cord-306424-gf0bglm0	234	9	IFN	IFN	NNP
cord-306424-gf0bglm0	234	10	-	-	HYPH
cord-306424-gf0bglm0	234	11	inducible	inducible	JJ
cord-306424-gf0bglm0	234	12	GTPases	gtpase	NNS
cord-306424-gf0bglm0	234	13	by	by	IN
cord-306424-gf0bglm0	234	14	IFN	IFN	NNP
cord-306424-gf0bglm0	234	15	-	-	HYPH
cord-306424-gf0bglm0	234	16	I	I	NNP
cord-306424-gf0bglm0	234	17	and	and	CC
cord-306424-gf0bglm0	234	18	-III	-iii	ADD
cord-306424-gf0bglm0	234	19	originating	originate	VBG
cord-306424-gf0bglm0	234	20	from	from	IN
cord-306424-gf0bglm0	234	21	various	various	JJ
cord-306424-gf0bglm0	234	22	cell	cell	NN
cord-306424-gf0bglm0	234	23	types	type	NNS
cord-306424-gf0bglm0	234	24	,	,	,
cord-306424-gf0bglm0	234	25	or	or	CC
cord-306424-gf0bglm0	234	26	IFN	IFN	NNP
cord-306424-gf0bglm0	234	27	-	-	HYPH
cord-306424-gf0bglm0	234	28	II	II	NNP
cord-306424-gf0bglm0	234	29	produced	produce	VBN
cord-306424-gf0bglm0	234	30	by	by	IN
cord-306424-gf0bglm0	234	31	specialized	specialized	JJ
cord-306424-gf0bglm0	234	32	immune	immune	JJ
cord-306424-gf0bglm0	234	33	cells	cell	NNS
cord-306424-gf0bglm0	234	34	,	,	,
cord-306424-gf0bglm0	234	35	disruption	disruption	NN
cord-306424-gf0bglm0	234	36	of	of	IN
cord-306424-gf0bglm0	234	37	ROs	ro	NNS
cord-306424-gf0bglm0	234	38	by	by	IN
cord-306424-gf0bglm0	234	39	IFN	IFN	NNP
cord-306424-gf0bglm0	234	40	-	-	HYPH
cord-306424-gf0bglm0	234	41	inducible	inducible	JJ
cord-306424-gf0bglm0	234	42	GTPases	gtpase	NNS
cord-306424-gf0bglm0	234	43	may	may	MD
cord-306424-gf0bglm0	234	44	result	result	VB
cord-306424-gf0bglm0	234	45	in	in	IN
cord-306424-gf0bglm0	234	46	enhanced	enhanced	JJ
cord-306424-gf0bglm0	234	47	exposure	exposure	NN
cord-306424-gf0bglm0	234	48	of	of	IN
cord-306424-gf0bglm0	234	49	viral	viral	JJ
cord-306424-gf0bglm0	234	50	RNA	RNA	NNP
cord-306424-gf0bglm0	234	51	,	,	,
cord-306424-gf0bglm0	234	52	thereby	thereby	RB
cord-306424-gf0bglm0	234	53	amplifying	amplify	VBG
cord-306424-gf0bglm0	234	54	the	the	DT
cord-306424-gf0bglm0	234	55	innate	innate	JJ
cord-306424-gf0bglm0	234	56	immune	immune	JJ
cord-306424-gf0bglm0	234	57	response	response	NN
cord-306424-gf0bglm0	234	58	and	and	CC
cord-306424-gf0bglm0	234	59	ensuring	ensure	VBG
cord-306424-gf0bglm0	234	60	efficient	efficient	JJ
cord-306424-gf0bglm0	234	61	clearance	clearance	NN
cord-306424-gf0bglm0	234	62	of	of	IN
cord-306424-gf0bglm0	234	63	the	the	DT
cord-306424-gf0bglm0	234	64	virus	virus	NN
cord-306424-gf0bglm0	234	65	.	.	.
cord-306424-gf0bglm0	235	1	However	however	RB
cord-306424-gf0bglm0	235	2	,	,	,
cord-306424-gf0bglm0	235	3	considering	consider	VBG
cord-306424-gf0bglm0	235	4	the	the	DT
cord-306424-gf0bglm0	235	5	differences	difference	NNS
cord-306424-gf0bglm0	235	6	in	in	IN
cord-306424-gf0bglm0	235	7	morphology	morphology	NN
cord-306424-gf0bglm0	235	8	and	and	CC
cord-306424-gf0bglm0	235	9	origin	origin	NN
cord-306424-gf0bglm0	235	10	of	of	IN
cord-306424-gf0bglm0	235	11	ROs	ROs	NNP
cord-306424-gf0bglm0	235	12	,	,	,
cord-306424-gf0bglm0	235	13	the	the	DT
cord-306424-gf0bglm0	235	14	variety	variety	NN
cord-306424-gf0bglm0	235	15	of	of	IN
cord-306424-gf0bglm0	235	16	infection	infection	NN
cord-306424-gf0bglm0	235	17	dynamics	dynamic	NNS
cord-306424-gf0bglm0	235	18	within	within	IN
cord-306424-gf0bglm0	235	19	the	the	DT
cord-306424-gf0bglm0	235	20	category	category	NN
cord-306424-gf0bglm0	235	21	of	of	IN
cord-306424-gf0bglm0	235	22	+	+	``
cord-306424-gf0bglm0	235	23	RNA	RNA	NNP
cord-306424-gf0bglm0	235	24	viruses	virus	NNS
cord-306424-gf0bglm0	235	25	,	,	,
cord-306424-gf0bglm0	235	26	and	and	CC
cord-306424-gf0bglm0	235	27	a	a	DT
cord-306424-gf0bglm0	235	28	lack	lack	NN
cord-306424-gf0bglm0	235	29	of	of	IN
cord-306424-gf0bglm0	235	30	knowledge	knowledge	NN
cord-306424-gf0bglm0	235	31	regarding	regard	VBG
cord-306424-gf0bglm0	235	32	the	the	DT
cord-306424-gf0bglm0	235	33	exact	exact	JJ
cord-306424-gf0bglm0	235	34	mechanism(s	mechanism(s	NNP
cord-306424-gf0bglm0	235	35	)	)	-RRB-
cord-306424-gf0bglm0	235	36	of	of	IN
cord-306424-gf0bglm0	235	37	disruption	disruption	NN
cord-306424-gf0bglm0	235	38	of	of	IN
cord-306424-gf0bglm0	235	39	non	non	JJ
cord-306424-gf0bglm0	235	40	/	/	JJ
cord-306424-gf0bglm0	235	41	aberrant	aberrant	JJ
cord-306424-gf0bglm0	235	42	-	-	HYPH
cord-306424-gf0bglm0	235	43	self	self	NN
cord-306424-gf0bglm0	235	44	membrane	membrane	NN
cord-306424-gf0bglm0	235	45	structures	structure	NNS
cord-306424-gf0bglm0	235	46	by	by	IN
cord-306424-gf0bglm0	235	47	IFNinducible	ifninducible	JJ
cord-306424-gf0bglm0	235	48	GTPases	gtpase	NNS
cord-306424-gf0bglm0	235	49	and	and	CC
cord-306424-gf0bglm0	235	50	possibly	possibly	RB
cord-306424-gf0bglm0	235	51	other	other	JJ
cord-306424-gf0bglm0	235	52	factors	factor	NNS
cord-306424-gf0bglm0	235	53	,	,	,
cord-306424-gf0bglm0	235	54	extensive	extensive	JJ
cord-306424-gf0bglm0	235	55	further	further	JJ
cord-306424-gf0bglm0	235	56	research	research	NN
cord-306424-gf0bglm0	235	57	is	be	VBZ
cord-306424-gf0bglm0	235	58	required	require	VBN
cord-306424-gf0bglm0	235	59	to	to	TO
cord-306424-gf0bglm0	235	60	elucidate	elucidate	VB
cord-306424-gf0bglm0	235	61	whether	whether	IN
cord-306424-gf0bglm0	235	62	this	this	DT
cord-306424-gf0bglm0	235	63	process	process	NN
cord-306424-gf0bglm0	235	64	plays	play	VBZ
cord-306424-gf0bglm0	235	65	a	a	DT
cord-306424-gf0bglm0	235	66	general	general	JJ
cord-306424-gf0bglm0	235	67	role	role	NN
cord-306424-gf0bglm0	235	68	in	in	IN
cord-306424-gf0bglm0	235	69	+	+	CC
cord-306424-gf0bglm0	235	70	RNA	RNA	NNP
cord-306424-gf0bglm0	235	71	virus	virus	NN
cord-306424-gf0bglm0	235	72	infection	infection	NN
cord-306424-gf0bglm0	235	73	,	,	,
cord-306424-gf0bglm0	235	74	and	and	CC
cord-306424-gf0bglm0	235	75	might	may	MD
cord-306424-gf0bglm0	235	76	open	open	VB
cord-306424-gf0bglm0	235	77	possibilities	possibility	NNS
cord-306424-gf0bglm0	235	78	for	for	IN
cord-306424-gf0bglm0	235	79	development	development	NN
cord-306424-gf0bglm0	235	80	of	of	IN
cord-306424-gf0bglm0	235	81	novel	novel	JJ
cord-306424-gf0bglm0	235	82	antiviral	antiviral	JJ
cord-306424-gf0bglm0	235	83	therapies	therapy	NNS
cord-306424-gf0bglm0	235	84	.	.	.
cord-306424-gf0bglm0	236	1	None	none	NN
cord-306424-gf0bglm0	236	2	Funding	funding	NN
cord-306424-gf0bglm0	237	1	This	this	DT
cord-306424-gf0bglm0	237	2	research	research	NN
cord-306424-gf0bglm0	237	3	did	do	VBD
cord-306424-gf0bglm0	237	4	not	not	RB
cord-306424-gf0bglm0	237	5	receive	receive	VB
cord-306424-gf0bglm0	237	6	any	any	DT
cord-306424-gf0bglm0	237	7	specific	specific	JJ
cord-306424-gf0bglm0	237	8	grant	grant	NN
cord-306424-gf0bglm0	237	9	from	from	IN
cord-306424-gf0bglm0	237	10	funding	fund	VBG
cord-306424-gf0bglm0	237	11	agencies	agency	NNS
cord-306424-gf0bglm0	237	12	in	in	IN
cord-306424-gf0bglm0	237	13	the	the	DT
cord-306424-gf0bglm0	237	14	public	public	NN
cord-306424-gf0bglm0	237	15	,	,	,
cord-306424-gf0bglm0	237	16	commercial	commercial	JJ
cord-306424-gf0bglm0	237	17	,	,	,
cord-306424-gf0bglm0	237	18	or	or	CC
cord-306424-gf0bglm0	237	19	not	not	RB
cord-306424-gf0bglm0	237	20	-	-	HYPH
cord-306424-gf0bglm0	237	21	for	for	IN
cord-306424-gf0bglm0	237	22	-	-	HYPH
cord-306424-gf0bglm0	237	23	profit	profit	NN
cord-306424-gf0bglm0	237	24	sectors	sector	NNS
cord-306424-gf0bglm0	237	25	.	.	.
cord-306424-gf0bglm0	238	1	Innate	innate	JJ
cord-306424-gf0bglm0	238	2	immune	immune	JJ
cord-306424-gf0bglm0	238	3	evasion	evasion	NN
cord-306424-gf0bglm0	238	4	strategies	strategy	NNS
cord-306424-gf0bglm0	238	5	of	of	IN
cord-306424-gf0bglm0	238	6	DNA	DNA	NNP
cord-306424-gf0bglm0	238	7	and	and	CC
cord-306424-gf0bglm0	238	8	RNA	RNA	NNP
cord-306424-gf0bglm0	238	9	viruses	virus	NNS
cord-306424-gf0bglm0	239	1	Innate	innate	JJ
cord-306424-gf0bglm0	239	2	immune	immune	JJ
cord-306424-gf0bglm0	239	3	recognition	recognition	NN
cord-306424-gf0bglm0	239	4	of	of	IN
cord-306424-gf0bglm0	239	5	viral	viral	JJ
cord-306424-gf0bglm0	239	6	infection	infection	NN
cord-306424-gf0bglm0	240	1	The	the	DT
cord-306424-gf0bglm0	240	2	response	response	NN
cord-306424-gf0bglm0	240	3	of	of	IN
cord-306424-gf0bglm0	240	4	mammalian	mammalian	JJ
cord-306424-gf0bglm0	240	5	cells	cell	NNS
cord-306424-gf0bglm0	240	6	to	to	IN
cord-306424-gf0bglm0	240	7	doublestranded	doublestranded	NNP
cord-306424-gf0bglm0	240	8	RNA	RNA	NNP
cord-306424-gf0bglm0	240	9	Innate	Innate	NNP
cord-306424-gf0bglm0	240	10	immune	immune	JJ
cord-306424-gf0bglm0	240	11	pattern	pattern	NN
cord-306424-gf0bglm0	240	12	recognition	recognition	NN
cord-306424-gf0bglm0	240	13	:	:	:
cord-306424-gf0bglm0	240	14	a	a	DT
cord-306424-gf0bglm0	240	15	cell	cell	NN
cord-306424-gf0bglm0	240	16	biological	biological	JJ
cord-306424-gf0bglm0	240	17	perspective	perspective	NN
cord-306424-gf0bglm0	240	18	Emerging	emerge	VBG
cord-306424-gf0bglm0	240	19	complexity	complexity	NN
cord-306424-gf0bglm0	240	20	and	and	CC
cord-306424-gf0bglm0	240	21	new	new	JJ
cord-306424-gf0bglm0	240	22	roles	role	NNS
cord-306424-gf0bglm0	240	23	for	for	IN
cord-306424-gf0bglm0	240	24	the	the	DT
cord-306424-gf0bglm0	240	25	RIG	rig	NN
cord-306424-gf0bglm0	240	26	-	-	HYPH
cord-306424-gf0bglm0	240	27	I	i	NN
cord-306424-gf0bglm0	240	28	-	-	HYPH
cord-306424-gf0bglm0	240	29	like	like	JJ
cord-306424-gf0bglm0	240	30	receptors	receptor	NNS
cord-306424-gf0bglm0	240	31	in	in	IN
cord-306424-gf0bglm0	240	32	innate	innate	JJ
cord-306424-gf0bglm0	240	33	antiviral	antiviral	JJ
cord-306424-gf0bglm0	240	34	immunity	immunity	NN
cord-306424-gf0bglm0	240	35	New	new	JJ
cord-306424-gf0bglm0	240	36	functions	function	NNS
cord-306424-gf0bglm0	240	37	of	of	IN
cord-306424-gf0bglm0	240	38	mitochondria	mitochondrion	NNS
cord-306424-gf0bglm0	240	39	associated	associate	VBD
cord-306424-gf0bglm0	240	40	membranes	membrane	NNS
cord-306424-gf0bglm0	240	41	in	in	IN
cord-306424-gf0bglm0	240	42	cellular	cellular	JJ
cord-306424-gf0bglm0	240	43	signaling	signaling	NN
cord-306424-gf0bglm0	241	1	The	the	DT
cord-306424-gf0bglm0	241	2	coming	coming	NN
cord-306424-gf0bglm0	241	3	of	of	IN
cord-306424-gf0bglm0	241	4	age	age	NN
cord-306424-gf0bglm0	241	5	of	of	IN
cord-306424-gf0bglm0	241	6	the	the	DT
cord-306424-gf0bglm0	241	7	mitochondria	mitochondrion	NNS
cord-306424-gf0bglm0	241	8	-	-	HYPH
cord-306424-gf0bglm0	241	9	ER	er	NN
cord-306424-gf0bglm0	241	10	contact	contact	NN
cord-306424-gf0bglm0	241	11	:	:	:
cord-306424-gf0bglm0	241	12	a	a	DT
cord-306424-gf0bglm0	241	13	matter	matter	NN
cord-306424-gf0bglm0	241	14	of	of	IN
cord-306424-gf0bglm0	241	15	thickness	thickness	NN
cord-306424-gf0bglm0	241	16	Mechanisms	mechanism	NNS
cord-306424-gf0bglm0	241	17	of	of	IN
cord-306424-gf0bglm0	241	18	innate	innate	JJ
cord-306424-gf0bglm0	241	19	immune	immune	JJ
cord-306424-gf0bglm0	241	20	evasion	evasion	NN
cord-306424-gf0bglm0	241	21	in	in	IN
cord-306424-gf0bglm0	241	22	re	re	NN
cord-306424-gf0bglm0	241	23	-	-	JJ
cord-306424-gf0bglm0	241	24	emerging	emerge	VBG
cord-306424-gf0bglm0	241	25	RNA	RNA	NNP
cord-306424-gf0bglm0	241	26	viruses	virus	NNS
cord-306424-gf0bglm0	241	27	Viral	viral	JJ
cord-306424-gf0bglm0	241	28	evasion	evasion	NN
cord-306424-gf0bglm0	241	29	of	of	IN
cord-306424-gf0bglm0	241	30	intracellular	intracellular	JJ
cord-306424-gf0bglm0	241	31	DNA	DNA	NNP
cord-306424-gf0bglm0	241	32	and	and	CC
cord-306424-gf0bglm0	241	33	RNA	RNA	NNP
cord-306424-gf0bglm0	241	34	sensing	sensing	NN
cord-306424-gf0bglm0	241	35	Modification	Modification	NNP
cord-306424-gf0bglm0	241	36	of	of	IN
cord-306424-gf0bglm0	241	37	intracellular	intracellular	JJ
cord-306424-gf0bglm0	241	38	membrane	membrane	NN
cord-306424-gf0bglm0	241	39	structures	structure	NNS
cord-306424-gf0bglm0	241	40	for	for	IN
cord-306424-gf0bglm0	241	41	virus	virus	NN
cord-306424-gf0bglm0	241	42	replication	replication	NN
cord-306424-gf0bglm0	241	43	Cytoplasmic	Cytoplasmic	NNP
cord-306424-gf0bglm0	241	44	viral	viral	JJ
cord-306424-gf0bglm0	241	45	replication	replication	NN
cord-306424-gf0bglm0	241	46	complexes	complex	NNS
cord-306424-gf0bglm0	242	1	Membranous	membranous	JJ
cord-306424-gf0bglm0	242	2	replication	replication	NN
cord-306424-gf0bglm0	242	3	factories	factory	NNS
cord-306424-gf0bglm0	242	4	induced	induce	VBN
cord-306424-gf0bglm0	242	5	by	by	IN
cord-306424-gf0bglm0	242	6	plus	plus	JJ
cord-306424-gf0bglm0	242	7	-	-	HYPH
cord-306424-gf0bglm0	242	8	strand	strand	NN
cord-306424-gf0bglm0	242	9	RNA	RNA	NNP
cord-306424-gf0bglm0	242	10	viruses	virus	NNS
cord-306424-gf0bglm0	242	11	Does	do	VBZ
cord-306424-gf0bglm0	242	12	form	form	VB
cord-306424-gf0bglm0	242	13	meet	meet	VB
cord-306424-gf0bglm0	242	14	function	function	NN
cord-306424-gf0bglm0	242	15	in	in	IN
cord-306424-gf0bglm0	242	16	the	the	DT
cord-306424-gf0bglm0	242	17	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	242	18	replicative	replicative	JJ
cord-306424-gf0bglm0	242	19	organelle	organelle	NN
cord-306424-gf0bglm0	242	20	?	?	.
cord-306424-gf0bglm0	243	1	Biogenesis	biogenesis	NN
cord-306424-gf0bglm0	243	2	and	and	CC
cord-306424-gf0bglm0	243	3	architecture	architecture	NN
cord-306424-gf0bglm0	243	4	of	of	IN
cord-306424-gf0bglm0	243	5	arterivirus	arterivirus	NN
cord-306424-gf0bglm0	243	6	replication	replication	NN
cord-306424-gf0bglm0	243	7	organelles	organelle	NNS
cord-306424-gf0bglm0	243	8	Severe	severe	JJ
cord-306424-gf0bglm0	243	9	acute	acute	JJ
cord-306424-gf0bglm0	243	10	respiratory	respiratory	JJ
cord-306424-gf0bglm0	243	11	syndrome	syndrome	NN
cord-306424-gf0bglm0	243	12	:	:	:
cord-306424-gf0bglm0	243	13	global	global	JJ
cord-306424-gf0bglm0	243	14	initiatives	initiative	NNS
cord-306424-gf0bglm0	243	15	for	for	IN
cord-306424-gf0bglm0	243	16	disease	disease	NN
cord-306424-gf0bglm0	243	17	diagnosis	diagnosis	NN
cord-306424-gf0bglm0	243	18	El	El	NNP
cord-306424-gf0bglm0	243	19	Hadi	Hadi	NNP
cord-306424-gf0bglm0	243	20	Mohamed	Mohamed	NNP
cord-306424-gf0bglm0	243	21	,	,	,
cord-306424-gf0bglm0	243	22	Outbreak	Outbreak	NNP
cord-306424-gf0bglm0	243	23	of	of	IN
cord-306424-gf0bglm0	243	24	Middle	Middle	NNP
cord-306424-gf0bglm0	243	25	East	East	NNP
cord-306424-gf0bglm0	243	26	respiratory	respiratory	JJ
cord-306424-gf0bglm0	243	27	syndrome	syndrome	NN
cord-306424-gf0bglm0	243	28	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	243	29	in	in	IN
cord-306424-gf0bglm0	243	30	Saudi	Saudi	NNP
cord-306424-gf0bglm0	243	31	Arabia	Arabia	NNP
cord-306424-gf0bglm0	243	32	:	:	:
cord-306424-gf0bglm0	243	33	a	a	DT
cord-306424-gf0bglm0	243	34	retrospective	retrospective	JJ
cord-306424-gf0bglm0	243	35	study	study	NN
cord-306424-gf0bglm0	243	36	Zika	Zika	NNP
cord-306424-gf0bglm0	243	37	:	:	:
cord-306424-gf0bglm0	243	38	the	the	DT
cord-306424-gf0bglm0	243	39	origin	origin	NN
cord-306424-gf0bglm0	243	40	and	and	CC
cord-306424-gf0bglm0	243	41	spread	spread	NN
cord-306424-gf0bglm0	243	42	of	of	IN
cord-306424-gf0bglm0	243	43	a	a	DT
cord-306424-gf0bglm0	243	44	mosquito	mosquito	NN
cord-306424-gf0bglm0	243	45	-	-	HYPH
cord-306424-gf0bglm0	243	46	borne	bear	VBN
cord-306424-gf0bglm0	243	47	virus	virus	NN
cord-306424-gf0bglm0	243	48	RNA	rna	NN
cord-306424-gf0bglm0	243	49	virus	virus	NN
cord-306424-gf0bglm0	243	50	replication	replication	NN
cord-306424-gf0bglm0	243	51	compartments	compartment	NNS
cord-306424-gf0bglm0	243	52	:	:	:
cord-306424-gf0bglm0	243	53	a	a	DT
cord-306424-gf0bglm0	243	54	safe	safe	JJ
cord-306424-gf0bglm0	243	55	home	home	NN
cord-306424-gf0bglm0	243	56	for	for	IN
cord-306424-gf0bglm0	243	57	(	(	-LRB-
cord-306424-gf0bglm0	243	58	most	most	JJS
cord-306424-gf0bglm0	243	59	)	)	-RRB-
cord-306424-gf0bglm0	243	60	viral	viral	JJ
cord-306424-gf0bglm0	243	61	replication	replication	NN
cord-306424-gf0bglm0	243	62	Architecture	architecture	NN
cord-306424-gf0bglm0	243	63	and	and	CC
cord-306424-gf0bglm0	243	64	biogenesis	biogenesis	NN
cord-306424-gf0bglm0	243	65	of	of	IN
cord-306424-gf0bglm0	243	66	plus	plus	JJ
cord-306424-gf0bglm0	243	67	-	-	HYPH
cord-306424-gf0bglm0	243	68	strand	strand	NN
cord-306424-gf0bglm0	243	69	RNA	RNA	NNP
cord-306424-gf0bglm0	243	70	virus	virus	NN
cord-306424-gf0bglm0	243	71	replication	replication	NN
cord-306424-gf0bglm0	243	72	factories	factory	NNS
cord-306424-gf0bglm0	244	1	New	new	JJ
cord-306424-gf0bglm0	244	2	insights	insight	NNS
cord-306424-gf0bglm0	244	3	on	on	IN
cord-306424-gf0bglm0	244	4	the	the	DT
cord-306424-gf0bglm0	244	5	role	role	NN
cord-306424-gf0bglm0	244	6	of	of	IN
cord-306424-gf0bglm0	244	7	paired	pair	VBN
cord-306424-gf0bglm0	244	8	membrane	membrane	NN
cord-306424-gf0bglm0	244	9	structures	structure	NNS
cord-306424-gf0bglm0	244	10	in	in	IN
cord-306424-gf0bglm0	244	11	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	244	12	replication	replication	NN
cord-306424-gf0bglm0	244	13	Composition	composition	NN
cord-306424-gf0bglm0	244	14	and	and	CC
cord-306424-gf0bglm0	244	15	threedimensional	threedimensional	JJ
cord-306424-gf0bglm0	244	16	architecture	architecture	NN
cord-306424-gf0bglm0	244	17	of	of	IN
cord-306424-gf0bglm0	244	18	the	the	DT
cord-306424-gf0bglm0	244	19	dengue	dengue	NN
cord-306424-gf0bglm0	244	20	virus	virus	NN
cord-306424-gf0bglm0	244	21	replication	replication	NN
cord-306424-gf0bglm0	244	22	and	and	CC
cord-306424-gf0bglm0	244	23	assembly	assembly	NN
cord-306424-gf0bglm0	244	24	sites	site	NNS
cord-306424-gf0bglm0	244	25	Cytoplasmic	Cytoplasmic	NNP
cord-306424-gf0bglm0	244	26	structures	structure	NNS
cord-306424-gf0bglm0	244	27	associated	associate	VBN
cord-306424-gf0bglm0	244	28	with	with	IN
cord-306424-gf0bglm0	244	29	an	an	DT
cord-306424-gf0bglm0	244	30	arbovirus	arbovirus	NN
cord-306424-gf0bglm0	244	31	infection	infection	NN
cord-306424-gf0bglm0	244	32	:	:	:
cord-306424-gf0bglm0	245	1	loci	locus	NNS
cord-306424-gf0bglm0	245	2	of	of	IN
cord-306424-gf0bglm0	245	3	viral	viral	JJ
cord-306424-gf0bglm0	245	4	ribonucleic	ribonucleic	NN
cord-306424-gf0bglm0	245	5	acid	acid	NN
cord-306424-gf0bglm0	245	6	synthesis	synthesis	NN
cord-306424-gf0bglm0	245	7	Biogenesis	biogenesis	NN
cord-306424-gf0bglm0	245	8	of	of	IN
cord-306424-gf0bglm0	245	9	the	the	DT
cord-306424-gf0bglm0	245	10	Semliki	Semliki	NNP
cord-306424-gf0bglm0	245	11	Forest	Forest	NNP
cord-306424-gf0bglm0	245	12	virus	virus	NN
cord-306424-gf0bglm0	245	13	RNA	RNA	NNP
cord-306424-gf0bglm0	245	14	replication	replication	NN
cord-306424-gf0bglm0	245	15	complex	complex	JJ
cord-306424-gf0bglm0	245	16	Threedimensional	Threedimensional	NNP
cord-306424-gf0bglm0	245	17	analysis	analysis	NN
cord-306424-gf0bglm0	245	18	of	of	IN
cord-306424-gf0bglm0	245	19	a	a	DT
cord-306424-gf0bglm0	245	20	viral	viral	JJ
cord-306424-gf0bglm0	245	21	RNA	RNA	NNP
cord-306424-gf0bglm0	245	22	replication	replication	NN
cord-306424-gf0bglm0	245	23	complex	complex	NN
cord-306424-gf0bglm0	245	24	reveals	reveal	VBZ
cord-306424-gf0bglm0	245	25	a	a	DT
cord-306424-gf0bglm0	245	26	virusinduced	virusinduced	JJ
cord-306424-gf0bglm0	245	27	mini	mini	NN
cord-306424-gf0bglm0	245	28	-	-	NN
cord-306424-gf0bglm0	245	29	organelle	organelle	NN
cord-306424-gf0bglm0	245	30	Alphavirus	Alphavirus	NNP
cord-306424-gf0bglm0	245	31	RNA	RNA	NNP
cord-306424-gf0bglm0	245	32	replicase	replicase	NN
cord-306424-gf0bglm0	245	33	is	be	VBZ
cord-306424-gf0bglm0	245	34	located	locate	VBN
cord-306424-gf0bglm0	245	35	on	on	IN
cord-306424-gf0bglm0	245	36	the	the	DT
cord-306424-gf0bglm0	245	37	cytoplasmic	cytoplasmic	JJ
cord-306424-gf0bglm0	245	38	surface	surface	NN
cord-306424-gf0bglm0	245	39	of	of	IN
cord-306424-gf0bglm0	245	40	endosomes	endosome	NNS
cord-306424-gf0bglm0	245	41	and	and	CC
cord-306424-gf0bglm0	245	42	lysosomes	lysosome	VBD
cord-306424-gf0bglm0	245	43	Ultrastructural	Ultrastructural	NNP
cord-306424-gf0bglm0	245	44	characterization	characterization	NN
cord-306424-gf0bglm0	245	45	and	and	CC
cord-306424-gf0bglm0	245	46	three	three	CD
cord-306424-gf0bglm0	245	47	-	-	HYPH
cord-306424-gf0bglm0	245	48	dimensional	dimensional	JJ
cord-306424-gf0bglm0	245	49	architecture	architecture	NN
cord-306424-gf0bglm0	245	50	of	of	IN
cord-306424-gf0bglm0	245	51	replication	replication	NN
cord-306424-gf0bglm0	245	52	sites	site	NNS
cord-306424-gf0bglm0	245	53	in	in	IN
cord-306424-gf0bglm0	245	54	dengue	dengue	NN
cord-306424-gf0bglm0	245	55	virus	virus	NN
cord-306424-gf0bglm0	245	56	-	-	HYPH
cord-306424-gf0bglm0	245	57	infected	infect	VBN
cord-306424-gf0bglm0	245	58	mosquito	mosquito	NN
cord-306424-gf0bglm0	245	59	cells	cell	NNS
cord-306424-gf0bglm0	245	60	Three	three	CD
cord-306424-gf0bglm0	245	61	-	-	HYPH
cord-306424-gf0bglm0	245	62	dimensional	dimensional	JJ
cord-306424-gf0bglm0	245	63	architecture	architecture	NN
cord-306424-gf0bglm0	245	64	and	and	CC
cord-306424-gf0bglm0	245	65	biogenesis	biogenesis	NN
cord-306424-gf0bglm0	245	66	of	of	IN
cord-306424-gf0bglm0	245	67	membrane	membrane	NN
cord-306424-gf0bglm0	245	68	structures	structure	NNS
cord-306424-gf0bglm0	245	69	associated	associate	VBN
cord-306424-gf0bglm0	245	70	with	with	IN
cord-306424-gf0bglm0	245	71	hepatitis	hepatitis	NN
cord-306424-gf0bglm0	245	72	C	C	NNP
cord-306424-gf0bglm0	245	73	virus	virus	NN
cord-306424-gf0bglm0	245	74	replication	replication	NN
cord-306424-gf0bglm0	245	75	Mutations	mutation	NNS
cord-306424-gf0bglm0	245	76	across	across	IN
cord-306424-gf0bglm0	245	77	murine	murine	JJ
cord-306424-gf0bglm0	245	78	hepatitis	hepatitis	NN
cord-306424-gf0bglm0	245	79	virus	virus	NN
cord-306424-gf0bglm0	245	80	nsp4	nsp4	CD
cord-306424-gf0bglm0	245	81	alter	alter	NN
cord-306424-gf0bglm0	245	82	virus	virus	NN
cord-306424-gf0bglm0	245	83	fitness	fitness	NN
cord-306424-gf0bglm0	245	84	and	and	CC
cord-306424-gf0bglm0	245	85	membrane	membrane	NN
cord-306424-gf0bglm0	245	86	modifications	modification	NNS
cord-306424-gf0bglm0	245	87	Competitive	competitive	JJ
cord-306424-gf0bglm0	245	88	fitness	fitness	NN
cord-306424-gf0bglm0	245	89	in	in	IN
cord-306424-gf0bglm0	245	90	coronaviruses	coronaviruse	NNS
cord-306424-gf0bglm0	245	91	is	be	VBZ
cord-306424-gf0bglm0	245	92	not	not	RB
cord-306424-gf0bglm0	245	93	correlated	correlate	VBN
cord-306424-gf0bglm0	245	94	with	with	IN
cord-306424-gf0bglm0	245	95	size	size	NN
cord-306424-gf0bglm0	245	96	or	or	CC
cord-306424-gf0bglm0	245	97	number	number	NN
cord-306424-gf0bglm0	245	98	of	of	IN
cord-306424-gf0bglm0	245	99	double	double	JJ
cord-306424-gf0bglm0	245	100	-	-	HYPH
cord-306424-gf0bglm0	245	101	membrane	membrane	NN
cord-306424-gf0bglm0	245	102	vesicles	vesicle	NNS
cord-306424-gf0bglm0	245	103	under	under	IN
cord-306424-gf0bglm0	245	104	reducedtemperature	reducedtemperature	JJ
cord-306424-gf0bglm0	245	105	growth	growth	NN
cord-306424-gf0bglm0	245	106	conditions	condition	NNS
cord-306424-gf0bglm0	246	1	SARS	SARS	NNP
cord-306424-gf0bglm0	246	2	-	-	HYPH
cord-306424-gf0bglm0	246	3	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	246	4	replication	replication	NN
cord-306424-gf0bglm0	246	5	is	be	VBZ
cord-306424-gf0bglm0	246	6	supported	support	VBN
cord-306424-gf0bglm0	246	7	by	by	IN
cord-306424-gf0bglm0	246	8	a	a	DT
cord-306424-gf0bglm0	246	9	reticulovesicular	reticulovesicular	JJ
cord-306424-gf0bglm0	246	10	network	network	NN
cord-306424-gf0bglm0	246	11	of	of	IN
cord-306424-gf0bglm0	246	12	modified	modify	VBN
cord-306424-gf0bglm0	246	13	endoplasmic	endoplasmic	NN
cord-306424-gf0bglm0	246	14	reticulum	reticulum	NN
cord-306424-gf0bglm0	246	15	Ultrastructural	Ultrastructural	NNP
cord-306424-gf0bglm0	246	16	characterization	characterization	NN
cord-306424-gf0bglm0	246	17	of	of	IN
cord-306424-gf0bglm0	246	18	arterivirus	arterivirus	NN
cord-306424-gf0bglm0	246	19	replication	replication	NN
cord-306424-gf0bglm0	246	20	structures	structure	NNS
cord-306424-gf0bglm0	246	21	:	:	:
cord-306424-gf0bglm0	246	22	reshaping	reshape	VBG
cord-306424-gf0bglm0	246	23	the	the	DT
cord-306424-gf0bglm0	246	24	endoplasmic	endoplasmic	NN
cord-306424-gf0bglm0	246	25	reticulum	reticulum	NN
cord-306424-gf0bglm0	246	26	to	to	TO
cord-306424-gf0bglm0	246	27	accommodate	accommodate	VB
cord-306424-gf0bglm0	246	28	viral	viral	JJ
cord-306424-gf0bglm0	246	29	RNA	RNA	NNP
cord-306424-gf0bglm0	246	30	synthesis	synthesis	NN
cord-306424-gf0bglm0	246	31	Expression	expression	NN
cord-306424-gf0bglm0	246	32	of	of	IN
cord-306424-gf0bglm0	246	33	hepatitis	hepatitis	NN
cord-306424-gf0bglm0	246	34	C	C	NNP
cord-306424-gf0bglm0	246	35	virus	virus	NN
cord-306424-gf0bglm0	246	36	proteins	protein	NNS
cord-306424-gf0bglm0	246	37	induces	induce	VBZ
cord-306424-gf0bglm0	246	38	distinct	distinct	JJ
cord-306424-gf0bglm0	246	39	membrane	membrane	NN
cord-306424-gf0bglm0	246	40	alterations	alteration	NNS
cord-306424-gf0bglm0	246	41	including	include	VBG
cord-306424-gf0bglm0	246	42	a	a	DT
cord-306424-gf0bglm0	246	43	candidate	candidate	NN
cord-306424-gf0bglm0	246	44	viral	viral	JJ
cord-306424-gf0bglm0	246	45	replication	replication	NN
cord-306424-gf0bglm0	246	46	complex	complex	JJ
cord-306424-gf0bglm0	246	47	Non	non	JJ
cord-306424-gf0bglm0	246	48	-	-	JJ
cord-306424-gf0bglm0	246	49	structural	structural	JJ
cord-306424-gf0bglm0	246	50	proteins	protein	NNS
cord-306424-gf0bglm0	246	51	2	2	CD
cord-306424-gf0bglm0	246	52	and	and	CC
cord-306424-gf0bglm0	246	53	3	3	CD
cord-306424-gf0bglm0	246	54	interact	interact	VBP
cord-306424-gf0bglm0	246	55	to	to	TO
cord-306424-gf0bglm0	246	56	modify	modify	VB
cord-306424-gf0bglm0	246	57	host	host	NN
cord-306424-gf0bglm0	246	58	cell	cell	NN
cord-306424-gf0bglm0	246	59	membranes	membrane	NNS
cord-306424-gf0bglm0	246	60	during	during	IN
cord-306424-gf0bglm0	246	61	the	the	DT
cord-306424-gf0bglm0	246	62	formation	formation	NN
cord-306424-gf0bglm0	246	63	of	of	IN
cord-306424-gf0bglm0	246	64	the	the	DT
cord-306424-gf0bglm0	246	65	arterivirus	arterivirus	NNP
cord-306424-gf0bglm0	246	66	replication	replication	NN
cord-306424-gf0bglm0	246	67	complex	complex	NN
cord-306424-gf0bglm0	246	68	Severe	severe	JJ
cord-306424-gf0bglm0	246	69	acute	acute	JJ
cord-306424-gf0bglm0	246	70	respiratory	respiratory	JJ
cord-306424-gf0bglm0	246	71	syndrome	syndrome	NN
cord-306424-gf0bglm0	246	72	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	246	73	nonstructural	nonstructural	JJ
cord-306424-gf0bglm0	246	74	proteins	protein	NNS
cord-306424-gf0bglm0	246	75	3	3	CD
cord-306424-gf0bglm0	246	76	,	,	,
cord-306424-gf0bglm0	246	77	4	4	CD
cord-306424-gf0bglm0	246	78	,	,	,
cord-306424-gf0bglm0	246	79	and	and	CC
cord-306424-gf0bglm0	246	80	6	6	CD
cord-306424-gf0bglm0	247	1	Induce	induce	VB
cord-306424-gf0bglm0	247	2	double	double	JJ
cord-306424-gf0bglm0	247	3	-	-	HYPH
cord-306424-gf0bglm0	247	4	membrane	membrane	NN
cord-306424-gf0bglm0	247	5	vesicles	vesicle	NNS
cord-306424-gf0bglm0	247	6	Type	type	NN
cord-306424-gf0bglm0	247	7	I	-PRON-	PRP
cord-306424-gf0bglm0	247	8	interferons	interferon	NNS
cord-306424-gf0bglm0	247	9	in	in	IN
cord-306424-gf0bglm0	247	10	infectious	infectious	JJ
cord-306424-gf0bglm0	247	11	disease	disease	NN
cord-306424-gf0bglm0	247	12	Secretion	secretion	NN
cord-306424-gf0bglm0	247	13	of	of	IN
cord-306424-gf0bglm0	247	14	interferon-(by	interferon-(by	JJ
cord-306424-gf0bglm0	247	15	human	human	JJ
cord-306424-gf0bglm0	247	16	macrophages	macrophage	NNS
cord-306424-gf0bglm0	247	17	demonstrated	demonstrate	VBD
cord-306424-gf0bglm0	247	18	at	at	IN
cord-306424-gf0bglm0	247	19	the	the	DT
cord-306424-gf0bglm0	247	20	single	single	JJ
cord-306424-gf0bglm0	247	21	-	-	HYPH
cord-306424-gf0bglm0	247	22	cell	cell	NN
cord-306424-gf0bglm0	247	23	level	level	NN
cord-306424-gf0bglm0	247	24	after	after	IN
cord-306424-gf0bglm0	247	25	costimulation	costimulation	NN
cord-306424-gf0bglm0	247	26	with	with	IN
cord-306424-gf0bglm0	247	27	interleukin	interleukin	NN
cord-306424-gf0bglm0	247	28	(	(	-LRB-
cord-306424-gf0bglm0	247	29	IL)-12	il)-12	NN
cord-306424-gf0bglm0	247	30	plus	plus	CC
cord-306424-gf0bglm0	247	31	IL-18	IL-18	NNP
cord-306424-gf0bglm0	247	32	Regulation	Regulation	NNP
cord-306424-gf0bglm0	247	33	of	of	IN
cord-306424-gf0bglm0	247	34	interferon	interferon	NN
cord-306424-gf0bglm0	247	35	-	-	HYPH
cord-306424-gf0bglm0	247	36	g	g	NN
cord-306424-gf0bglm0	247	37	during	during	IN
cord-306424-gf0bglm0	247	38	innate	innate	JJ
cord-306424-gf0bglm0	247	39	and	and	CC
cord-306424-gf0bglm0	247	40	adaptive	adaptive	JJ
cord-306424-gf0bglm0	247	41	immune	immune	JJ
cord-306424-gf0bglm0	247	42	responses	response	NNS
cord-306424-gf0bglm0	247	43	Mechanisms	mechanism	NNS
cord-306424-gf0bglm0	247	44	of	of	IN
cord-306424-gf0bglm0	247	45	type	type	NN
cord-306424-gf0bglm0	247	46	III	iii	CD
cord-306424-gf0bglm0	248	1	interferon	interferon	NNP
cord-306424-gf0bglm0	248	2	expression	expression	NN
cord-306424-gf0bglm0	249	1	IFN	IFN	NNP
cord-306424-gf0bglm0	249	2	-	-	HYPH
cord-306424-gf0bglm0	249	3	lambda	lambda	NNP
cord-306424-gf0bglm0	249	4	(	(	-LRB-
cord-306424-gf0bglm0	249	5	IFN-	IFN-	NNP
cord-306424-gf0bglm0	249	6	?	?	.
cord-306424-gf0bglm0	249	7	?	?	.
cord-306424-gf0bglm0	249	8	)	)	-RRB-
cord-306424-gf0bglm0	249	9	is	be	VBZ
cord-306424-gf0bglm0	249	10	expressed	express	VBN
cord-306424-gf0bglm0	249	11	in	in	IN
cord-306424-gf0bglm0	249	12	a	a	DT
cord-306424-gf0bglm0	249	13	tissue	tissue	NN
cord-306424-gf0bglm0	249	14	-	-	HYPH
cord-306424-gf0bglm0	249	15	dependent	dependent	JJ
cord-306424-gf0bglm0	249	16	fashion	fashion	NN
cord-306424-gf0bglm0	249	17	and	and	CC
cord-306424-gf0bglm0	249	18	primarily	primarily	RB
cord-306424-gf0bglm0	249	19	acts	act	VBZ
cord-306424-gf0bglm0	249	20	on	on	IN
cord-306424-gf0bglm0	249	21	epithelial	epithelial	JJ
cord-306424-gf0bglm0	249	22	cells	cell	NNS
cord-306424-gf0bglm0	249	23	in	in	IN
cord-306424-gf0bglm0	249	24	vivo	vivo	NNP
cord-306424-gf0bglm0	249	25	Severe	severe	JJ
cord-306424-gf0bglm0	249	26	acute	acute	JJ
cord-306424-gf0bglm0	249	27	respiratory	respiratory	JJ
cord-306424-gf0bglm0	249	28	syndrome	syndrome	NN
cord-306424-gf0bglm0	249	29	-	-	HYPH
cord-306424-gf0bglm0	249	30	related	relate	VBN
cord-306424-gf0bglm0	249	31	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	249	32	is	be	VBZ
cord-306424-gf0bglm0	249	33	inhibited	inhibit	VBN
cord-306424-gf0bglm0	249	34	by	by	IN
cord-306424-gf0bglm0	249	35	interferon	interferon	NN
cord-306424-gf0bglm0	249	36	-	-	HYPH
cord-306424-gf0bglm0	249	37	alpha	alpha	NN
cord-306424-gf0bglm0	249	38	Interferon	interferon	NN
cord-306424-gf0bglm0	249	39	-	-	HYPH
cord-306424-gf0bglm0	249	40	beta	beta	NN
cord-306424-gf0bglm0	249	41	and	and	CC
cord-306424-gf0bglm0	249	42	interferongamma	interferongamma	NN
cord-306424-gf0bglm0	249	43	synergistically	synergistically	RB
cord-306424-gf0bglm0	249	44	inhibit	inhibit	VBP
cord-306424-gf0bglm0	249	45	the	the	DT
cord-306424-gf0bglm0	249	46	replication	replication	NN
cord-306424-gf0bglm0	249	47	of	of	IN
cord-306424-gf0bglm0	249	48	severe	severe	JJ
cord-306424-gf0bglm0	249	49	acute	acute	JJ
cord-306424-gf0bglm0	249	50	respiratory	respiratory	JJ
cord-306424-gf0bglm0	249	51	syndrome	syndrome	NN
cord-306424-gf0bglm0	249	52	-	-	HYPH
cord-306424-gf0bglm0	249	53	associated	associate	VBN
cord-306424-gf0bglm0	249	54	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	249	55	(	(	-LRB-
cord-306424-gf0bglm0	249	56	SARS	SARS	NNP
cord-306424-gf0bglm0	249	57	-	-	HYPH
cord-306424-gf0bglm0	249	58	CoV	CoV	NNP
cord-306424-gf0bglm0	249	59	)	)	-RRB-
cord-306424-gf0bglm0	249	60	Evaluation	Evaluation	NNP
cord-306424-gf0bglm0	249	61	of	of	IN
cord-306424-gf0bglm0	249	62	immunomodulators	immunomodulator	NNS
cord-306424-gf0bglm0	249	63	,	,	,
cord-306424-gf0bglm0	249	64	interferons	interferon	NNS
cord-306424-gf0bglm0	249	65	and	and	CC
cord-306424-gf0bglm0	249	66	known	know	VBN
cord-306424-gf0bglm0	249	67	in	in	IN
cord-306424-gf0bglm0	249	68	vitro	vitro	FW
cord-306424-gf0bglm0	249	69	SARS	SARS	NNP
cord-306424-gf0bglm0	249	70	-	-	HYPH
cord-306424-gf0bglm0	249	71	CoV	CoV	NNP
cord-306424-gf0bglm0	249	72	inhibitors	inhibitor	NNS
cord-306424-gf0bglm0	249	73	for	for	IN
cord-306424-gf0bglm0	249	74	inhibition	inhibition	NN
cord-306424-gf0bglm0	249	75	of	of	IN
cord-306424-gf0bglm0	249	76	SARS	SARS	NNP
cord-306424-gf0bglm0	249	77	-	-	HYPH
cord-306424-gf0bglm0	249	78	CoV	cov	NN
cord-306424-gf0bglm0	249	79	replication	replication	NN
cord-306424-gf0bglm0	249	80	in	in	IN
cord-306424-gf0bglm0	249	81	BALB	BALB	NNP
cord-306424-gf0bglm0	249	82	/	/	SYM
cord-306424-gf0bglm0	249	83	c	c	NN
cord-306424-gf0bglm0	249	84	mice	mice	NN
cord-306424-gf0bglm0	249	85	Single	single	JJ
cord-306424-gf0bglm0	249	86	-	-	HYPH
cord-306424-gf0bglm0	249	87	dose	dose	NN
cord-306424-gf0bglm0	249	88	intranasal	intranasal	NN
cord-306424-gf0bglm0	249	89	administration	administration	NN
cord-306424-gf0bglm0	249	90	with	with	IN
cord-306424-gf0bglm0	249	91	mDEF201	mDEF201	NNP
cord-306424-gf0bglm0	250	1	(	(	-LRB-
cord-306424-gf0bglm0	250	2	adenovirus	adenovirus	NN
cord-306424-gf0bglm0	250	3	vectored	vectore	VBD
cord-306424-gf0bglm0	250	4	mouse	mouse	NNP
cord-306424-gf0bglm0	250	5	interferonalpha	interferonalpha	NNP
cord-306424-gf0bglm0	250	6	)	)	-RRB-
cord-306424-gf0bglm0	250	7	confers	confer	VBZ
cord-306424-gf0bglm0	250	8	protection	protection	NN
cord-306424-gf0bglm0	250	9	from	from	IN
cord-306424-gf0bglm0	250	10	mortality	mortality	NN
cord-306424-gf0bglm0	250	11	in	in	IN
cord-306424-gf0bglm0	250	12	a	a	DT
cord-306424-gf0bglm0	250	13	lethal	lethal	JJ
cord-306424-gf0bglm0	250	14	SARS	SARS	NNP
cord-306424-gf0bglm0	250	15	-	-	HYPH
cord-306424-gf0bglm0	250	16	CoV	CoV	NNP
cord-306424-gf0bglm0	250	17	BALB	BALB	NNP
cord-306424-gf0bglm0	250	18	/	/	SYM
cord-306424-gf0bglm0	250	19	c	c	NNP
cord-306424-gf0bglm0	250	20	mouse	mouse	NN
cord-306424-gf0bglm0	250	21	model	model	NN
cord-306424-gf0bglm0	250	22	Immune	Immune	NNP
cord-306424-gf0bglm0	250	23	signaling	signal	VBG
cord-306424-gf0bglm0	250	24	by	by	IN
cord-306424-gf0bglm0	250	25	RIG	rig	NN
cord-306424-gf0bglm0	250	26	-	-	HYPH
cord-306424-gf0bglm0	250	27	I	i	NN
cord-306424-gf0bglm0	250	28	-	-	HYPH
cord-306424-gf0bglm0	250	29	like	like	JJ
cord-306424-gf0bglm0	250	30	receptors	receptor	NNS
cord-306424-gf0bglm0	250	31	Intracellular	Intracellular	NNP
cord-306424-gf0bglm0	250	32	detection	detection	NN
cord-306424-gf0bglm0	250	33	of	of	IN
cord-306424-gf0bglm0	250	34	viral	viral	JJ
cord-306424-gf0bglm0	250	35	nucleic	nucleic	JJ
cord-306424-gf0bglm0	250	36	acids	acid	NNS
cord-306424-gf0bglm0	250	37	IPS-1	IPS-1	NNP
cord-306424-gf0bglm0	250	38	,	,	,
cord-306424-gf0bglm0	250	39	an	an	DT
cord-306424-gf0bglm0	250	40	adaptor	adaptor	NN
cord-306424-gf0bglm0	250	41	triggering	trigger	VBG
cord-306424-gf0bglm0	250	42	RIG	rig	NN
cord-306424-gf0bglm0	250	43	-	-	HYPH
cord-306424-gf0bglm0	250	44	I	i	NN
cord-306424-gf0bglm0	250	45	-	-	HYPH
cord-306424-gf0bglm0	250	46	and	and	CC
cord-306424-gf0bglm0	250	47	Mda5-mediated	Mda5-mediated	NNP
cord-306424-gf0bglm0	250	48	type	type	NN
cord-306424-gf0bglm0	251	1	I	-PRON-	PRP
cord-306424-gf0bglm0	252	1	interferon	interferon	NNP
cord-306424-gf0bglm0	252	2	induction	induction	NN
cord-306424-gf0bglm0	252	3	Cardif	Cardif	NNP
cord-306424-gf0bglm0	252	4	is	be	VBZ
cord-306424-gf0bglm0	252	5	an	an	DT
cord-306424-gf0bglm0	252	6	adaptor	adaptor	NN
cord-306424-gf0bglm0	252	7	protein	protein	NN
cord-306424-gf0bglm0	252	8	in	in	IN
cord-306424-gf0bglm0	252	9	the	the	DT
cord-306424-gf0bglm0	252	10	RIG	rig	NN
cord-306424-gf0bglm0	252	11	-	-	:
cord-306424-gf0bglm0	252	12	I	I	NNP
cord-306424-gf0bglm0	252	13	antiviral	antiviral	JJ
cord-306424-gf0bglm0	252	14	pathway	pathway	NN
cord-306424-gf0bglm0	252	15	and	and	CC
cord-306424-gf0bglm0	252	16	is	be	VBZ
cord-306424-gf0bglm0	252	17	targeted	target	VBN
cord-306424-gf0bglm0	252	18	by	by	IN
cord-306424-gf0bglm0	252	19	hepatitis	hepatitis	NN
cord-306424-gf0bglm0	252	20	C	C	NNP
cord-306424-gf0bglm0	252	21	virus	virus	NN
cord-306424-gf0bglm0	252	22	Identification	identification	NN
cord-306424-gf0bglm0	252	23	and	and	CC
cord-306424-gf0bglm0	252	24	characterization	characterization	NN
cord-306424-gf0bglm0	252	25	of	of	IN
cord-306424-gf0bglm0	252	26	MAVS	MAVS	NNPS
cord-306424-gf0bglm0	252	27	,	,	,
cord-306424-gf0bglm0	252	28	a	a	DT
cord-306424-gf0bglm0	252	29	mitochondrial	mitochondrial	JJ
cord-306424-gf0bglm0	252	30	antiviral	antiviral	JJ
cord-306424-gf0bglm0	252	31	signaling	signal	VBG
cord-306424-gf0bglm0	252	32	protein	protein	NN
cord-306424-gf0bglm0	252	33	that	that	WDT
cord-306424-gf0bglm0	252	34	activates	activate	VBZ
cord-306424-gf0bglm0	252	35	NF	NF	NNP
cord-306424-gf0bglm0	252	36	VISA	VISA	NNP
cord-306424-gf0bglm0	252	37	is	be	VBZ
cord-306424-gf0bglm0	252	38	an	an	DT
cord-306424-gf0bglm0	252	39	adapter	adapter	NN
cord-306424-gf0bglm0	252	40	protein	protein	NN
cord-306424-gf0bglm0	252	41	required	require	VBN
cord-306424-gf0bglm0	252	42	for	for	IN
cord-306424-gf0bglm0	252	43	virus	virus	NN
cord-306424-gf0bglm0	252	44	-	-	HYPH
cord-306424-gf0bglm0	252	45	triggered	trigger	VBN
cord-306424-gf0bglm0	252	46	IFN-	IFN-	NNP
cord-306424-gf0bglm0	252	47	?	?	.
cord-306424-gf0bglm0	252	48	.	.	.
cord-306424-gf0bglm0	252	49	?	?	.
cord-306424-gf0bglm0	252	50	.	.	.
cord-306424-gf0bglm0	253	1	signaling	signal	VBG
cord-306424-gf0bglm0	253	2	Mitochondria	mitochondrion	NNS
cord-306424-gf0bglm0	253	3	in	in	IN
cord-306424-gf0bglm0	253	4	innate	innate	JJ
cord-306424-gf0bglm0	253	5	immune	immune	JJ
cord-306424-gf0bglm0	253	6	responses	response	NNS
cord-306424-gf0bglm0	253	7	Toll	toll	NN
cord-306424-gf0bglm0	253	8	-	-	HYPH
cord-306424-gf0bglm0	253	9	like	like	JJ
cord-306424-gf0bglm0	253	10	receptors	receptor	NNS
cord-306424-gf0bglm0	253	11	in	in	IN
cord-306424-gf0bglm0	253	12	antiviral	antiviral	JJ
cord-306424-gf0bglm0	253	13	innate	innate	JJ
cord-306424-gf0bglm0	253	14	immunity	immunity	NN
cord-306424-gf0bglm0	253	15	Immune	immune	JJ
cord-306424-gf0bglm0	253	16	evasion	evasion	NN
cord-306424-gf0bglm0	253	17	of	of	IN
cord-306424-gf0bglm0	253	18	porcine	porcine	JJ
cord-306424-gf0bglm0	253	19	enteric	enteric	JJ
cord-306424-gf0bglm0	253	20	coronaviruses	coronaviruse	NNS
cord-306424-gf0bglm0	253	21	and	and	CC
cord-306424-gf0bglm0	253	22	viral	viral	JJ
cord-306424-gf0bglm0	253	23	modulation	modulation	NN
cord-306424-gf0bglm0	253	24	of	of	IN
cord-306424-gf0bglm0	253	25	antiviral	antiviral	JJ
cord-306424-gf0bglm0	253	26	innate	innate	NN
cord-306424-gf0bglm0	253	27	signaling	signaling	NN
cord-306424-gf0bglm0	254	1	SARS	SARS	NNP
cord-306424-gf0bglm0	254	2	-	-	HYPH
cord-306424-gf0bglm0	254	3	CoV	CoV	NNP
cord-306424-gf0bglm0	254	4	pathogenesis	pathogenesis	NN
cord-306424-gf0bglm0	254	5	is	be	VBZ
cord-306424-gf0bglm0	254	6	regulated	regulate	VBN
cord-306424-gf0bglm0	254	7	by	by	IN
cord-306424-gf0bglm0	254	8	a	a	DT
cord-306424-gf0bglm0	254	9	STAT1	stat1	NN
cord-306424-gf0bglm0	254	10	dependent	dependent	JJ
cord-306424-gf0bglm0	254	11	but	but	CC
cord-306424-gf0bglm0	254	12	a	a	DT
cord-306424-gf0bglm0	254	13	type	type	NN
cord-306424-gf0bglm0	255	1	I	-PRON-	PRP
cord-306424-gf0bglm0	255	2	,	,	,
cord-306424-gf0bglm0	255	3	II	II	NNP
cord-306424-gf0bglm0	255	4	and	and	CC
cord-306424-gf0bglm0	255	5	III	iii	CD
cord-306424-gf0bglm0	255	6	interferon	interferon	NN
cord-306424-gf0bglm0	255	7	receptor	receptor	NN
cord-306424-gf0bglm0	255	8	independent	independent	JJ
cord-306424-gf0bglm0	255	9	mechanism	mechanism	NN
cord-306424-gf0bglm0	256	1	Interferon	interferon	NN
cord-306424-gf0bglm0	256	2	-	-	HYPH
cord-306424-gf0bglm0	256	3	stimulated	stimulate	VBN
cord-306424-gf0bglm0	256	4	genes	gene	NNS
cord-306424-gf0bglm0	256	5	and	and	CC
cord-306424-gf0bglm0	256	6	their	-PRON-	PRP$
cord-306424-gf0bglm0	256	7	antiviral	antiviral	JJ
cord-306424-gf0bglm0	256	8	effector	effector	NN
cord-306424-gf0bglm0	256	9	functions	function	NNS
cord-306424-gf0bglm0	257	1	Interferon	interferon	NN
cord-306424-gf0bglm0	257	2	-	-	HYPH
cord-306424-gf0bglm0	257	3	inducible	inducible	JJ
cord-306424-gf0bglm0	257	4	antiviral	antiviral	JJ
cord-306424-gf0bglm0	257	5	effectors	effector	NNS
cord-306424-gf0bglm0	258	1	Interferon	interferon	NN
cord-306424-gf0bglm0	258	2	-	-	HYPH
cord-306424-gf0bglm0	258	3	stimulated	stimulate	VBN
cord-306424-gf0bglm0	258	4	genes	gene	NNS
cord-306424-gf0bglm0	258	5	and	and	CC
cord-306424-gf0bglm0	258	6	their	-PRON-	PRP$
cord-306424-gf0bglm0	258	7	protein	protein	NN
cord-306424-gf0bglm0	258	8	products	product	NNS
cord-306424-gf0bglm0	258	9	:	:	:
cord-306424-gf0bglm0	259	1	what	what	WP
cord-306424-gf0bglm0	259	2	and	and	CC
cord-306424-gf0bglm0	259	3	how	how	WRB
cord-306424-gf0bglm0	259	4	?	?	.
cord-306424-gf0bglm0	260	1	ERIS	ERIS	NNP
cord-306424-gf0bglm0	260	2	,	,	,
cord-306424-gf0bglm0	260	3	an	an	DT
cord-306424-gf0bglm0	260	4	endoplasmic	endoplasmic	NN
cord-306424-gf0bglm0	260	5	reticulum	reticulum	NN
cord-306424-gf0bglm0	260	6	IFN	IFN	NNP
cord-306424-gf0bglm0	260	7	stimulator	stimulator	NN
cord-306424-gf0bglm0	260	8	,	,	,
cord-306424-gf0bglm0	260	9	activates	activate	VBZ
cord-306424-gf0bglm0	260	10	innate	innate	JJ
cord-306424-gf0bglm0	260	11	immune	immune	NN
cord-306424-gf0bglm0	260	12	signaling	signal	VBG
cord-306424-gf0bglm0	260	13	through	through	IN
cord-306424-gf0bglm0	260	14	dimerization	dimerization	NN
cord-306424-gf0bglm0	260	15	Mitochondrial	mitochondrial	NN
cord-306424-gf0bglm0	260	16	-	-	HYPH
cord-306424-gf0bglm0	260	17	associated	associate	VBN
cord-306424-gf0bglm0	260	18	endoplasmic	endoplasmic	NN
cord-306424-gf0bglm0	260	19	reticulum	reticulum	NN
cord-306424-gf0bglm0	260	20	membranes	membrane	NNS
cord-306424-gf0bglm0	260	21	{	{	-LRB-
cord-306424-gf0bglm0	260	22	(	(	-LRB-
cord-306424-gf0bglm0	260	23	MAM	MAM	NNP
cord-306424-gf0bglm0	260	24	)	)	-RRB-
cord-306424-gf0bglm0	260	25	}	}	-RRB-
cord-306424-gf0bglm0	260	26	form	form	VBP
cord-306424-gf0bglm0	260	27	innate	innate	JJ
cord-306424-gf0bglm0	260	28	immune	immune	JJ
cord-306424-gf0bglm0	260	29	synapses	synapsis	NNS
cord-306424-gf0bglm0	260	30	and	and	CC
cord-306424-gf0bglm0	260	31	are	be	VBP
cord-306424-gf0bglm0	260	32	targeted	target	VBN
cord-306424-gf0bglm0	260	33	by	by	IN
cord-306424-gf0bglm0	260	34	hepatitis	hepatitis	NN
cord-306424-gf0bglm0	260	35	C	C	NNP
cord-306424-gf0bglm0	260	36	virus	virus	NN
cord-306424-gf0bglm0	260	37	Peroxisomes	Peroxisomes	NNPS
cord-306424-gf0bglm0	260	38	are	be	VBP
cord-306424-gf0bglm0	260	39	signaling	signal	VBG
cord-306424-gf0bglm0	260	40	platforms	platform	NNS
cord-306424-gf0bglm0	260	41	for	for	IN
cord-306424-gf0bglm0	260	42	antiviral	antiviral	JJ
cord-306424-gf0bglm0	260	43	innate	innate	JJ
cord-306424-gf0bglm0	260	44	immunity	immunity	NN
cord-306424-gf0bglm0	260	45	ACBD5	acbd5	NN
cord-306424-gf0bglm0	260	46	and	and	CC
cord-306424-gf0bglm0	260	47	VAPB	VAPB	NNP
cord-306424-gf0bglm0	260	48	mediate	mediate	VBP
cord-306424-gf0bglm0	260	49	membrane	membrane	NN
cord-306424-gf0bglm0	260	50	associations	association	NNS
cord-306424-gf0bglm0	260	51	between	between	IN
cord-306424-gf0bglm0	260	52	peroxisomes	peroxisome	NNS
cord-306424-gf0bglm0	260	53	and	and	CC
cord-306424-gf0bglm0	260	54	the	the	DT
cord-306424-gf0bglm0	260	55	ER	ER	NNP
cord-306424-gf0bglm0	260	56	Organelle	Organelle	NNP
cord-306424-gf0bglm0	260	57	dynamics	dynamic	NNS
cord-306424-gf0bglm0	260	58	:	:	:
cord-306424-gf0bglm0	260	59	connections	connection	NNS
cord-306424-gf0bglm0	260	60	,	,	,
cord-306424-gf0bglm0	260	61	connections	connection	NNS
cord-306424-gf0bglm0	260	62	,	,	,
cord-306424-gf0bglm0	260	63	connections	connection	NNS
cord-306424-gf0bglm0	260	64	,	,	,
cord-306424-gf0bglm0	260	65	Nat	Nat	NNP
cord-306424-gf0bglm0	260	66	Rev	Rev	NNP
cord-306424-gf0bglm0	260	67	VAPs	vap	NNS
cord-306424-gf0bglm0	260	68	and	and	CC
cord-306424-gf0bglm0	260	69	ACBD5	acbd5	NN
cord-306424-gf0bglm0	260	70	tether	tether	NN
cord-306424-gf0bglm0	260	71	peroxisomes	peroxisome	NNS
cord-306424-gf0bglm0	260	72	to	to	IN
cord-306424-gf0bglm0	260	73	the	the	DT
cord-306424-gf0bglm0	260	74	ER	ER	NNP
cord-306424-gf0bglm0	260	75	for	for	IN
cord-306424-gf0bglm0	260	76	peroxisome	peroxisome	NN
cord-306424-gf0bglm0	260	77	maintenance	maintenance	NN
cord-306424-gf0bglm0	260	78	and	and	CC
cord-306424-gf0bglm0	260	79	lipid	lipid	NN
cord-306424-gf0bglm0	260	80	homeostasis	homeostasis	NN
cord-306424-gf0bglm0	260	81	.	.	.
cord-306424-gf0bglm0	261	1	,	,	,
cord-306424-gf0bglm0	261	2	Cheng	Cheng	NNP
cord-306424-gf0bglm0	261	3	Antiviral	Antiviral	NNP
cord-306424-gf0bglm0	261	4	innate	innate	JJ
cord-306424-gf0bglm0	261	5	immunity	immunity	NN
cord-306424-gf0bglm0	261	6	and	and	CC
cord-306424-gf0bglm0	261	7	stress	stress	NN
cord-306424-gf0bglm0	261	8	granule	granule	NN
cord-306424-gf0bglm0	261	9	responses	response	NNS
cord-306424-gf0bglm0	262	1	Dynamic	dynamic	JJ
cord-306424-gf0bglm0	262	2	oscillation	oscillation	NN
cord-306424-gf0bglm0	262	3	of	of	IN
cord-306424-gf0bglm0	262	4	translation	translation	NN
cord-306424-gf0bglm0	262	5	and	and	CC
cord-306424-gf0bglm0	262	6	stress	stress	NN
cord-306424-gf0bglm0	262	7	granule	granule	NN
cord-306424-gf0bglm0	262	8	formation	formation	NN
cord-306424-gf0bglm0	262	9	mark	mark	VBP
cord-306424-gf0bglm0	262	10	the	the	DT
cord-306424-gf0bglm0	262	11	cellular	cellular	JJ
cord-306424-gf0bglm0	262	12	response	response	NN
cord-306424-gf0bglm0	262	13	to	to	IN
cord-306424-gf0bglm0	262	14	virus	virus	NN
cord-306424-gf0bglm0	262	15	infection	infection	NN
cord-306424-gf0bglm0	262	16	Critical	critical	JJ
cord-306424-gf0bglm0	262	17	role	role	NN
cord-306424-gf0bglm0	262	18	of	of	IN
cord-306424-gf0bglm0	262	19	an	an	DT
cord-306424-gf0bglm0	262	20	antiviral	antiviral	JJ
cord-306424-gf0bglm0	262	21	stress	stress	NN
cord-306424-gf0bglm0	262	22	granule	granule	NN
cord-306424-gf0bglm0	262	23	containing	contain	VBG
cord-306424-gf0bglm0	262	24	RIG	rig	NN
cord-306424-gf0bglm0	262	25	-	-	:
cord-306424-gf0bglm0	262	26	I	I	NNP
cord-306424-gf0bglm0	262	27	and	and	CC
cord-306424-gf0bglm0	262	28	PKR	PKR	NNP
cord-306424-gf0bglm0	262	29	in	in	IN
cord-306424-gf0bglm0	262	30	viral	viral	JJ
cord-306424-gf0bglm0	262	31	detection	detection	NN
cord-306424-gf0bglm0	262	32	and	and	CC
cord-306424-gf0bglm0	263	1	innate	innate	JJ
cord-306424-gf0bglm0	263	2	immunity	immunity	NN
cord-306424-gf0bglm0	263	3	Encephalomyocarditis	Encephalomyocarditis	NNP
cord-306424-gf0bglm0	263	4	virus	virus	NN
cord-306424-gf0bglm0	263	5	disrupts	disrupt	VBZ
cord-306424-gf0bglm0	263	6	stress	stress	NN
cord-306424-gf0bglm0	263	7	granules	granule	NNS
cord-306424-gf0bglm0	263	8	,	,	,
cord-306424-gf0bglm0	263	9	the	the	DT
cord-306424-gf0bglm0	263	10	critical	critical	JJ
cord-306424-gf0bglm0	263	11	platform	platform	NN
cord-306424-gf0bglm0	263	12	for	for	IN
cord-306424-gf0bglm0	263	13	triggering	trigger	VBG
cord-306424-gf0bglm0	263	14	antiviral	antiviral	JJ
cord-306424-gf0bglm0	263	15	innate	innate	JJ
cord-306424-gf0bglm0	263	16	immune	immune	JJ
cord-306424-gf0bglm0	263	17	responses	response	NNS
cord-306424-gf0bglm0	263	18	MDA5	MDA5	NNP
cord-306424-gf0bglm0	263	19	localizes	localize	VBZ
cord-306424-gf0bglm0	263	20	to	to	IN
cord-306424-gf0bglm0	263	21	stress	stress	NN
cord-306424-gf0bglm0	263	22	granules	granule	NNS
cord-306424-gf0bglm0	263	23	,	,	,
cord-306424-gf0bglm0	263	24	but	but	CC
cord-306424-gf0bglm0	263	25	this	this	DT
cord-306424-gf0bglm0	263	26	localization	localization	NN
cord-306424-gf0bglm0	263	27	is	be	VBZ
cord-306424-gf0bglm0	263	28	not	not	RB
cord-306424-gf0bglm0	263	29	required	require	VBN
cord-306424-gf0bglm0	263	30	for	for	IN
cord-306424-gf0bglm0	263	31	the	the	DT
cord-306424-gf0bglm0	263	32	induction	induction	NN
cord-306424-gf0bglm0	263	33	of	of	IN
cord-306424-gf0bglm0	263	34	type	type	NN
cord-306424-gf0bglm0	264	1	I	-PRON-	PRP
cord-306424-gf0bglm0	264	2	interferon	interferon	VBD
cord-306424-gf0bglm0	264	3	Characterization	Characterization	NNP
cord-306424-gf0bglm0	264	4	of	of	IN
cord-306424-gf0bglm0	264	5	RNA	RNA	NNP
cord-306424-gf0bglm0	264	6	synthesis	synthesis	NN
cord-306424-gf0bglm0	264	7	,	,	,
cord-306424-gf0bglm0	264	8	replication	replication	NN
cord-306424-gf0bglm0	264	9	mechanism	mechanism	NN
cord-306424-gf0bglm0	264	10	,	,	,
cord-306424-gf0bglm0	264	11	and	and	CC
cord-306424-gf0bglm0	264	12	in	in	IN
cord-306424-gf0bglm0	264	13	vitro	vitro	FW
cord-306424-gf0bglm0	264	14	RNA	rna	NN
cord-306424-gf0bglm0	264	15	-	-	HYPH
cord-306424-gf0bglm0	264	16	dependent	dependent	JJ
cord-306424-gf0bglm0	264	17	RNA	RNA	NNP
cord-306424-gf0bglm0	264	18	polymerase	polymerase	NN
cord-306424-gf0bglm0	264	19	activity	activity	NN
cord-306424-gf0bglm0	264	20	of	of	IN
cord-306424-gf0bglm0	264	21	Japanese	japanese	JJ
cord-306424-gf0bglm0	264	22	encephalitis	encephalitis	RB
cord-306424-gf0bglm0	264	23	virus	virus	NN
cord-306424-gf0bglm0	264	24	Architecture	architecture	NN
cord-306424-gf0bglm0	264	25	of	of	IN
cord-306424-gf0bglm0	264	26	the	the	DT
cord-306424-gf0bglm0	264	27	flaviviral	flaviviral	JJ
cord-306424-gf0bglm0	264	28	replication	replication	NN
cord-306424-gf0bglm0	264	29	complex	complex	NN
cord-306424-gf0bglm0	264	30	:	:	:
cord-306424-gf0bglm0	264	31	protease	protease	NN
cord-306424-gf0bglm0	264	32	,	,	,
cord-306424-gf0bglm0	264	33	nuclease	nuclease	FW
cord-306424-gf0bglm0	264	34	,	,	,
cord-306424-gf0bglm0	264	35	and	and	CC
cord-306424-gf0bglm0	265	1	detergents	detergent	NNS
cord-306424-gf0bglm0	265	2	reveal	reveal	VBP
cord-306424-gf0bglm0	265	3	encasement	encasement	NN
cord-306424-gf0bglm0	265	4	within	within	IN
cord-306424-gf0bglm0	265	5	double	double	RB
cord-306424-gf0bglm0	265	6	-	-	HYPH
cord-306424-gf0bglm0	265	7	layered	layered	JJ
cord-306424-gf0bglm0	265	8	membrane	membrane	NN
cord-306424-gf0bglm0	265	9	compartments	compartment	NNS
cord-306424-gf0bglm0	266	1	SARS	SARS	NNP
cord-306424-gf0bglm0	266	2	-	-	HYPH
cord-306424-gf0bglm0	266	3	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	266	4	replication	replication	NN
cord-306424-gf0bglm0	266	5	/	/	SYM
cord-306424-gf0bglm0	266	6	transcription	transcription	NN
cord-306424-gf0bglm0	266	7	complexes	complex	NNS
cord-306424-gf0bglm0	266	8	are	be	VBP
cord-306424-gf0bglm0	266	9	membrane	membrane	NN
cord-306424-gf0bglm0	266	10	-	-	HYPH
cord-306424-gf0bglm0	266	11	protected	protect	VBN
cord-306424-gf0bglm0	266	12	and	and	CC
cord-306424-gf0bglm0	266	13	need	need	VB
cord-306424-gf0bglm0	266	14	a	a	DT
cord-306424-gf0bglm0	266	15	host	host	NN
cord-306424-gf0bglm0	266	16	factor	factor	NN
cord-306424-gf0bglm0	266	17	for	for	IN
cord-306424-gf0bglm0	266	18	activity	activity	NN
cord-306424-gf0bglm0	266	19	in	in	IN
cord-306424-gf0bglm0	266	20	vitro	vitro	FW
cord-306424-gf0bglm0	266	21	The	the	DT
cord-306424-gf0bglm0	266	22	in	in	FW
cord-306424-gf0bglm0	266	23	vitro	vitro	FW
cord-306424-gf0bglm0	266	24	RNA	rna	NN
cord-306424-gf0bglm0	266	25	synthesizing	synthesize	VBG
cord-306424-gf0bglm0	266	26	activity	activity	NN
cord-306424-gf0bglm0	266	27	of	of	IN
cord-306424-gf0bglm0	266	28	the	the	DT
cord-306424-gf0bglm0	266	29	isolated	isolate	VBN
cord-306424-gf0bglm0	266	30	arterivirus	arterivirus	NN
cord-306424-gf0bglm0	266	31	replication	replication	NN
cord-306424-gf0bglm0	266	32	/	/	SYM
cord-306424-gf0bglm0	266	33	transcription	transcription	NN
cord-306424-gf0bglm0	266	34	complex	complex	NN
cord-306424-gf0bglm0	266	35	is	be	VBZ
cord-306424-gf0bglm0	266	36	dependent	dependent	JJ
cord-306424-gf0bglm0	266	37	on	on	IN
cord-306424-gf0bglm0	266	38	a	a	DT
cord-306424-gf0bglm0	266	39	host	host	NN
cord-306424-gf0bglm0	266	40	factor	factor	NN
cord-306424-gf0bglm0	266	41	The	the	DT
cord-306424-gf0bglm0	266	42	dengue	dengue	NN
cord-306424-gf0bglm0	266	43	virus	virus	NN
cord-306424-gf0bglm0	266	44	conceals	conceal	VBZ
cord-306424-gf0bglm0	266	45	doublestranded	doublestrande	VBN
cord-306424-gf0bglm0	266	46	RNA	RNA	NNP
cord-306424-gf0bglm0	266	47	in	in	IN
cord-306424-gf0bglm0	266	48	the	the	DT
cord-306424-gf0bglm0	266	49	intracellular	intracellular	JJ
cord-306424-gf0bglm0	266	50	membrane	membrane	NN
cord-306424-gf0bglm0	266	51	to	to	TO
cord-306424-gf0bglm0	266	52	escape	escape	VB
cord-306424-gf0bglm0	266	53	from	from	IN
cord-306424-gf0bglm0	266	54	an	an	DT
cord-306424-gf0bglm0	266	55	interferon	interferon	NN
cord-306424-gf0bglm0	266	56	response	response	NN
cord-306424-gf0bglm0	266	57	0	0	CD
cord-306424-gf0bglm0	267	1	-O	-O	:
cord-306424-gf0bglm0	267	2	methylation	methylation	NN
cord-306424-gf0bglm0	267	3	of	of	IN
cord-306424-gf0bglm0	267	4	the	the	DT
cord-306424-gf0bglm0	267	5	viral	viral	JJ
cord-306424-gf0bglm0	267	6	mRNA	mRNA	NNP
cord-306424-gf0bglm0	267	7	cap	cap	NN
cord-306424-gf0bglm0	267	8	evades	evade	VBZ
cord-306424-gf0bglm0	267	9	host	host	NN
cord-306424-gf0bglm0	267	10	restriction	restriction	NN
cord-306424-gf0bglm0	267	11	by	by	IN
cord-306424-gf0bglm0	267	12	IFIT	IFIT	NNP
cord-306424-gf0bglm0	267	13	family	family	NN
cord-306424-gf0bglm0	267	14	members	member	NNS
cord-306424-gf0bglm0	267	15	Attenuation	attenuation	NN
cord-306424-gf0bglm0	267	16	and	and	CC
cord-306424-gf0bglm0	267	17	restoration	restoration	NN
cord-306424-gf0bglm0	267	18	of	of	IN
cord-306424-gf0bglm0	267	19	SARS	SARS	NNP
cord-306424-gf0bglm0	267	20	-	-	HYPH
cord-306424-gf0bglm0	267	21	CoV	CoV	NNP
cord-306424-gf0bglm0	267	22	mutant	mutant	NN
cord-306424-gf0bglm0	267	23	lacking	lack	VBG
cord-306424-gf0bglm0	267	24	2	2	CD
cord-306424-gf0bglm0	267	25	0	0	CD
cord-306424-gf0bglm0	267	26	O	o	NN
cord-306424-gf0bglm0	267	27	methyltransferase	methyltransferase	NN
cord-306424-gf0bglm0	267	28	activity	activity	NN
cord-306424-gf0bglm0	267	29	Rational	rational	JJ
cord-306424-gf0bglm0	267	30	design	design	NN
cord-306424-gf0bglm0	267	31	of	of	IN
cord-306424-gf0bglm0	267	32	a	a	DT
cord-306424-gf0bglm0	267	33	flavivirus	flavivirus	JJ
cord-306424-gf0bglm0	267	34	vaccine	vaccine	NN
cord-306424-gf0bglm0	267	35	by	by	IN
cord-306424-gf0bglm0	267	36	abolishing	abolish	VBG
cord-306424-gf0bglm0	267	37	viral	viral	JJ
cord-306424-gf0bglm0	267	38	RNA	RNA	NNP
cord-306424-gf0bglm0	267	39	2	2	CD
cord-306424-gf0bglm0	267	40	0	0	CD
cord-306424-gf0bglm0	268	1	-O	-O	:
cord-306424-gf0bglm0	268	2	methylation	methylation	NN
cord-306424-gf0bglm0	268	3	Early	early	RB
cord-306424-gf0bglm0	268	4	endonuclease	endonuclease	NN
cord-306424-gf0bglm0	268	5	-	-	HYPH
cord-306424-gf0bglm0	268	6	mediated	mediate	VBN
cord-306424-gf0bglm0	268	7	evasion	evasion	NN
cord-306424-gf0bglm0	268	8	of	of	IN
cord-306424-gf0bglm0	268	9	RNA	RNA	NNP
cord-306424-gf0bglm0	268	10	sensing	sensing	NN
cord-306424-gf0bglm0	268	11	ensures	ensure	VBZ
cord-306424-gf0bglm0	268	12	efficient	efficient	JJ
cord-306424-gf0bglm0	268	13	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	268	14	replication	replication	NN
cord-306424-gf0bglm0	268	15	Hepatitis	Hepatitis	NNP
cord-306424-gf0bglm0	268	16	C	C	NNP
cord-306424-gf0bglm0	268	17	virus	virus	NN
cord-306424-gf0bglm0	268	18	protease	protease	NN
cord-306424-gf0bglm0	268	19	NS3/	NS3/	NNP
cord-306424-gf0bglm0	268	20	4A	4a	CD
cord-306424-gf0bglm0	268	21	cleaves	cleave	VBZ
cord-306424-gf0bglm0	268	22	mitochondrial	mitochondrial	JJ
cord-306424-gf0bglm0	268	23	antiviral	antiviral	JJ
cord-306424-gf0bglm0	268	24	signaling	signal	VBG
cord-306424-gf0bglm0	268	25	protein	protein	NN
cord-306424-gf0bglm0	268	26	off	off	IN
cord-306424-gf0bglm0	268	27	the	the	DT
cord-306424-gf0bglm0	268	28	mitochondria	mitochondrion	NNS
cord-306424-gf0bglm0	268	29	to	to	TO
cord-306424-gf0bglm0	268	30	evade	evade	VB
cord-306424-gf0bglm0	268	31	innate	innate	JJ
cord-306424-gf0bglm0	268	32	immunity	immunity	NN
cord-306424-gf0bglm0	268	33	Regulation	regulation	NN
cord-306424-gf0bglm0	268	34	of	of	IN
cord-306424-gf0bglm0	268	35	interferon	interferon	NN
cord-306424-gf0bglm0	268	36	regulatory	regulatory	JJ
cord-306424-gf0bglm0	268	37	factor-3	factor-3	NNP
cord-306424-gf0bglm0	268	38	by	by	IN
cord-306424-gf0bglm0	268	39	the	the	DT
cord-306424-gf0bglm0	268	40	hepatitis	hepatitis	NN
cord-306424-gf0bglm0	268	41	C	C	NNP
cord-306424-gf0bglm0	268	42	virus	virus	NN
cord-306424-gf0bglm0	268	43	serine	serine	NN
cord-306424-gf0bglm0	268	44	protease	protease	NN
cord-306424-gf0bglm0	268	45	Control	Control	NNP
cord-306424-gf0bglm0	268	46	of	of	IN
cord-306424-gf0bglm0	268	47	antiviral	antiviral	JJ
cord-306424-gf0bglm0	268	48	defenses	defense	NNS
cord-306424-gf0bglm0	268	49	through	through	IN
cord-306424-gf0bglm0	268	50	hepatitis	hepatitis	NN
cord-306424-gf0bglm0	268	51	C	C	NNP
cord-306424-gf0bglm0	268	52	virus	virus	NN
cord-306424-gf0bglm0	268	53	disruption	disruption	NN
cord-306424-gf0bglm0	268	54	of	of	IN
cord-306424-gf0bglm0	268	55	retinoic	retinoic	JJ
cord-306424-gf0bglm0	268	56	acid	acid	NN
cord-306424-gf0bglm0	268	57	-	-	HYPH
cord-306424-gf0bglm0	268	58	inducible	inducible	JJ
cord-306424-gf0bglm0	268	59	gene	gene	NN
cord-306424-gf0bglm0	268	60	-	-	:
cord-306424-gf0bglm0	268	61	I	i	NN
cord-306424-gf0bglm0	268	62	signaling	signal	VBG
cord-306424-gf0bglm0	268	63	Viral	viral	JJ
cord-306424-gf0bglm0	268	64	and	and	CC
cord-306424-gf0bglm0	268	65	therapeutic	therapeutic	JJ
cord-306424-gf0bglm0	268	66	control	control	NN
cord-306424-gf0bglm0	268	67	of	of	IN
cord-306424-gf0bglm0	268	68	IFN	IFN	NNP
cord-306424-gf0bglm0	268	69	-	-	HYPH
cord-306424-gf0bglm0	268	70	beta	beta	NN
cord-306424-gf0bglm0	268	71	promoter	promoter	NN
cord-306424-gf0bglm0	268	72	stimulator	stimulator	NN
cord-306424-gf0bglm0	268	73	1	1	CD
cord-306424-gf0bglm0	268	74	during	during	IN
cord-306424-gf0bglm0	268	75	hepatitis	hepatitis	NN
cord-306424-gf0bglm0	268	76	C	C	NNP
cord-306424-gf0bglm0	268	77	virus	virus	NN
cord-306424-gf0bglm0	268	78	infection	infection	NN
cord-306424-gf0bglm0	269	1	The	the	DT
cord-306424-gf0bglm0	269	2	nonstructural	nonstructural	JJ
cord-306424-gf0bglm0	269	3	protein	protein	NN
cord-306424-gf0bglm0	269	4	4A	4a	CD
cord-306424-gf0bglm0	269	5	of	of	IN
cord-306424-gf0bglm0	269	6	dengue	dengue	NN
cord-306424-gf0bglm0	269	7	virus	virus	NN
cord-306424-gf0bglm0	269	8	is	be	VBZ
cord-306424-gf0bglm0	269	9	an	an	DT
cord-306424-gf0bglm0	269	10	integral	integral	JJ
cord-306424-gf0bglm0	269	11	membrane	membrane	NN
cord-306424-gf0bglm0	269	12	protein	protein	NN
cord-306424-gf0bglm0	269	13	inducing	induce	VBG
cord-306424-gf0bglm0	269	14	membrane	membrane	NN
cord-306424-gf0bglm0	269	15	alterations	alteration	NNS
cord-306424-gf0bglm0	269	16	in	in	IN
cord-306424-gf0bglm0	269	17	a	a	DT
cord-306424-gf0bglm0	269	18	2K	2k	RB
cord-306424-gf0bglm0	269	19	-	-	HYPH
cord-306424-gf0bglm0	269	20	regulated	regulate	VBN
cord-306424-gf0bglm0	269	21	manner	manner	NN
cord-306424-gf0bglm0	269	22	Dengue	dengue	NN
cord-306424-gf0bglm0	269	23	virus	virus	NN
cord-306424-gf0bglm0	269	24	subverts	subvert	VBZ
cord-306424-gf0bglm0	269	25	host	host	NN
cord-306424-gf0bglm0	269	26	innate	innate	JJ
cord-306424-gf0bglm0	269	27	immunity	immunity	NN
cord-306424-gf0bglm0	269	28	by	by	IN
cord-306424-gf0bglm0	269	29	targeting	target	VBG
cord-306424-gf0bglm0	269	30	adaptor	adaptor	NN
cord-306424-gf0bglm0	269	31	protein	protein	NN
cord-306424-gf0bglm0	269	32	MAVS	MAVS	NNP
cord-306424-gf0bglm0	269	33	Inhibition	inhibition	NN
cord-306424-gf0bglm0	269	34	of	of	IN
cord-306424-gf0bglm0	269	35	the	the	DT
cord-306424-gf0bglm0	269	36	type	type	NN
cord-306424-gf0bglm0	270	1	I	-PRON-	PRP
cord-306424-gf0bglm0	271	1	interferon	interferon	NNP
cord-306424-gf0bglm0	271	2	response	response	NN
cord-306424-gf0bglm0	271	3	in	in	IN
cord-306424-gf0bglm0	271	4	human	human	JJ
cord-306424-gf0bglm0	271	5	dendritic	dendritic	JJ
cord-306424-gf0bglm0	271	6	cells	cell	NNS
cord-306424-gf0bglm0	271	7	by	by	IN
cord-306424-gf0bglm0	271	8	dengue	dengue	NN
cord-306424-gf0bglm0	271	9	virus	virus	NN
cord-306424-gf0bglm0	271	10	infection	infection	NN
cord-306424-gf0bglm0	271	11	requires	require	VBZ
cord-306424-gf0bglm0	271	12	a	a	DT
cord-306424-gf0bglm0	271	13	catalytically	catalytically	RB
cord-306424-gf0bglm0	271	14	active	active	JJ
cord-306424-gf0bglm0	271	15	NS2B3	ns2b3	NN
cord-306424-gf0bglm0	271	16	complex	complex	JJ
cord-306424-gf0bglm0	271	17	Dengue	Dengue	NNP
cord-306424-gf0bglm0	271	18	virus	virus	NN
cord-306424-gf0bglm0	271	19	targets	target	VBZ
cord-306424-gf0bglm0	271	20	the	the	DT
cord-306424-gf0bglm0	271	21	adaptor	adaptor	NN
cord-306424-gf0bglm0	271	22	protein	protein	NN
cord-306424-gf0bglm0	271	23	MITA	MITA	NNP
cord-306424-gf0bglm0	271	24	to	to	TO
cord-306424-gf0bglm0	271	25	subvert	subvert	VB
cord-306424-gf0bglm0	271	26	host	host	NN
cord-306424-gf0bglm0	271	27	innate	innate	JJ
cord-306424-gf0bglm0	271	28	immunity	immunity	NN
cord-306424-gf0bglm0	271	29	DENV	DENV	NNP
cord-306424-gf0bglm0	271	30	inhibits	inhibit	VBZ
cord-306424-gf0bglm0	271	31	type	type	NN
cord-306424-gf0bglm0	272	1	I	-PRON-	PRP
cord-306424-gf0bglm0	272	2	IFN	IFN	NNP
cord-306424-gf0bglm0	272	3	production	production	NN
cord-306424-gf0bglm0	272	4	in	in	IN
cord-306424-gf0bglm0	272	5	infected	infected	JJ
cord-306424-gf0bglm0	272	6	cells	cell	NNS
cord-306424-gf0bglm0	272	7	by	by	IN
cord-306424-gf0bglm0	272	8	cleaving	cleave	VBG
cord-306424-gf0bglm0	272	9	human	human	JJ
cord-306424-gf0bglm0	272	10	STING	STING	NNP
cord-306424-gf0bglm0	272	11	Hepatitis	Hepatitis	NNP
cord-306424-gf0bglm0	272	12	C	C	NNP
cord-306424-gf0bglm0	272	13	virus	virus	NN
cord-306424-gf0bglm0	272	14	NS4	NS4	NNP
cord-306424-gf0bglm0	272	15	B	B	NNP
cord-306424-gf0bglm0	272	16	blocks	block	VBZ
cord-306424-gf0bglm0	272	17	the	the	DT
cord-306424-gf0bglm0	272	18	interaction	interaction	NN
cord-306424-gf0bglm0	272	19	of	of	IN
cord-306424-gf0bglm0	272	20	STING	sting	NN
cord-306424-gf0bglm0	272	21	and	and	CC
cord-306424-gf0bglm0	272	22	TBK1	TBK1	NNP
cord-306424-gf0bglm0	272	23	to	to	TO
cord-306424-gf0bglm0	272	24	evade	evade	VB
cord-306424-gf0bglm0	272	25	host	host	NN
cord-306424-gf0bglm0	272	26	innate	innate	JJ
cord-306424-gf0bglm0	272	27	immunity	immunity	NN
cord-306424-gf0bglm0	272	28	Hepatitis	Hepatitis	NNP
cord-306424-gf0bglm0	272	29	C	C	NNP
cord-306424-gf0bglm0	272	30	virus	virus	NN
cord-306424-gf0bglm0	272	31	NS4	NS4	NNP
cord-306424-gf0bglm0	272	32	B	B	NNP
cord-306424-gf0bglm0	272	33	protein	protein	NN
cord-306424-gf0bglm0	272	34	targets	target	NNS
cord-306424-gf0bglm0	272	35	STING	sting	VB
cord-306424-gf0bglm0	272	36	and	and	CC
cord-306424-gf0bglm0	272	37	abrogates	abrogate	VBZ
cord-306424-gf0bglm0	272	38	RIG	rig	NN
cord-306424-gf0bglm0	272	39	-	-	HYPH
cord-306424-gf0bglm0	272	40	I	i	NN
cord-306424-gf0bglm0	272	41	-	-	HYPH
cord-306424-gf0bglm0	272	42	mediated	mediate	VBN
cord-306424-gf0bglm0	272	43	type	type	NN
cord-306424-gf0bglm0	273	1	I	-PRON-	PRP
cord-306424-gf0bglm0	273	2	interferon	interferon	NN
cord-306424-gf0bglm0	273	3	-	-	HYPH
cord-306424-gf0bglm0	273	4	dependent	dependent	JJ
cord-306424-gf0bglm0	273	5	innate	innate	JJ
cord-306424-gf0bglm0	273	6	immunity	immunity	NN
cord-306424-gf0bglm0	274	1	Nidovirus	Nidovirus	NNP
cord-306424-gf0bglm0	274	2	papain	papain	NN
cord-306424-gf0bglm0	274	3	-	-	HYPH
cord-306424-gf0bglm0	274	4	like	like	JJ
cord-306424-gf0bglm0	274	5	proteases	protease	NNS
cord-306424-gf0bglm0	274	6	:	:	:
cord-306424-gf0bglm0	274	7	multifunctional	multifunctional	JJ
cord-306424-gf0bglm0	274	8	enzymes	enzyme	NNS
cord-306424-gf0bglm0	274	9	with	with	IN
cord-306424-gf0bglm0	274	10	protease	protease	NN
cord-306424-gf0bglm0	274	11	,	,	,
cord-306424-gf0bglm0	274	12	deubiquitinating	deubiquitinating	NN
cord-306424-gf0bglm0	274	13	and	and	CC
cord-306424-gf0bglm0	274	14	deISGylating	deisgylate	VBG
cord-306424-gf0bglm0	274	15	activities	activity	NNS
cord-306424-gf0bglm0	275	1	Deubiquitinase	deubiquitinase	UH
cord-306424-gf0bglm0	275	2	function	function	NN
cord-306424-gf0bglm0	275	3	of	of	IN
cord-306424-gf0bglm0	275	4	arterivirus	arterivirus	NNP
cord-306424-gf0bglm0	275	5	papain	papain	NN
cord-306424-gf0bglm0	275	6	-	-	HYPH
cord-306424-gf0bglm0	275	7	like	like	JJ
cord-306424-gf0bglm0	275	8	protease	protease	NN
cord-306424-gf0bglm0	275	9	2	2	CD
cord-306424-gf0bglm0	275	10	suppresses	suppress	VBZ
cord-306424-gf0bglm0	275	11	the	the	DT
cord-306424-gf0bglm0	275	12	innate	innate	JJ
cord-306424-gf0bglm0	275	13	immune	immune	JJ
cord-306424-gf0bglm0	275	14	response	response	NN
cord-306424-gf0bglm0	275	15	in	in	IN
cord-306424-gf0bglm0	275	16	infected	infected	JJ
cord-306424-gf0bglm0	275	17	host	host	NN
cord-306424-gf0bglm0	275	18	cells	cell	NNS
cord-306424-gf0bglm0	275	19	Crystal	Crystal	NNP
cord-306424-gf0bglm0	275	20	structure	structure	NN
cord-306424-gf0bglm0	275	21	of	of	IN
cord-306424-gf0bglm0	275	22	the	the	DT
cord-306424-gf0bglm0	275	23	middle	middle	NNP
cord-306424-gf0bglm0	275	24	east	east	NNP
cord-306424-gf0bglm0	275	25	respiratory	respiratory	JJ
cord-306424-gf0bglm0	275	26	syndrome	syndrome	NN
cord-306424-gf0bglm0	275	27	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	275	28	(	(	-LRB-
cord-306424-gf0bglm0	275	29	MERS	MERS	NNP
cord-306424-gf0bglm0	275	30	-	-	HYPH
cord-306424-gf0bglm0	275	31	CoV	CoV	NNP
cord-306424-gf0bglm0	275	32	)	)	-RRB-
cord-306424-gf0bglm0	276	1	papain	papain	NN
cord-306424-gf0bglm0	276	2	-	-	HYPH
cord-306424-gf0bglm0	276	3	like	like	JJ
cord-306424-gf0bglm0	276	4	protease	protease	NN
cord-306424-gf0bglm0	276	5	bound	bind	VBN
cord-306424-gf0bglm0	276	6	to	to	IN
cord-306424-gf0bglm0	276	7	ubiquitin	ubiquitin	NN
cord-306424-gf0bglm0	276	8	facilitates	facilitate	VBZ
cord-306424-gf0bglm0	276	9	targeted	target	VBN
cord-306424-gf0bglm0	276	10	disruption	disruption	NN
cord-306424-gf0bglm0	276	11	of	of	IN
cord-306424-gf0bglm0	276	12	deubiquitinating	deubiquitinate	VBG
cord-306424-gf0bglm0	276	13	activity	activity	NN
cord-306424-gf0bglm0	276	14	to	to	TO
cord-306424-gf0bglm0	276	15	demonstrate	demonstrate	VB
cord-306424-gf0bglm0	276	16	its	-PRON-	PRP$
cord-306424-gf0bglm0	276	17	role	role	NN
cord-306424-gf0bglm0	276	18	in	in	IN
cord-306424-gf0bglm0	276	19	innate	innate	JJ
cord-306424-gf0bglm0	276	20	immune	immune	JJ
cord-306424-gf0bglm0	276	21	suppression	suppression	NN
cord-306424-gf0bglm0	276	22	Dengue	dengue	NN
cord-306424-gf0bglm0	276	23	virus	virus	NN
cord-306424-gf0bglm0	276	24	subverts	subvert	VBZ
cord-306424-gf0bglm0	276	25	the	the	DT
cord-306424-gf0bglm0	276	26	interferon	interferon	NN
cord-306424-gf0bglm0	276	27	induction	induction	NN
cord-306424-gf0bglm0	276	28	pathway	pathway	NN
cord-306424-gf0bglm0	276	29	via	via	IN
cord-306424-gf0bglm0	276	30	NS2B/3	NS2B/3	NNP
cord-306424-gf0bglm0	276	31	protease	protease	NN
cord-306424-gf0bglm0	276	32	-	-	HYPH
cord-306424-gf0bglm0	276	33	I(B	i(b	NN
cord-306424-gf0bglm0	276	34	kinase	kinase	NN
cord-306424-gf0bglm0	276	35	(	(	-LRB-
cord-306424-gf0bglm0	276	36	interaction	interaction	NN
cord-306424-gf0bglm0	276	37	,	,	,
cord-306424-gf0bglm0	276	38	Clin	Clin	NNP
cord-306424-gf0bglm0	276	39	The	the	DT
cord-306424-gf0bglm0	276	40	membrane	membrane	NN
cord-306424-gf0bglm0	276	41	protein	protein	NN
cord-306424-gf0bglm0	276	42	of	of	IN
cord-306424-gf0bglm0	276	43	SARS	SARS	NNP
cord-306424-gf0bglm0	276	44	-	-	HYPH
cord-306424-gf0bglm0	276	45	CoV	CoV	NNP
cord-306424-gf0bglm0	276	46	suppresses	suppress	VBZ
cord-306424-gf0bglm0	276	47	NF	NF	NNP
cord-306424-gf0bglm0	276	48	-	-	HYPH
cord-306424-gf0bglm0	276	49	kappaB	kappaB	NNP
cord-306424-gf0bglm0	276	50	activation	activation	NN
cord-306424-gf0bglm0	276	51	Severe	severe	JJ
cord-306424-gf0bglm0	276	52	acute	acute	JJ
cord-306424-gf0bglm0	276	53	respiratory	respiratory	JJ
cord-306424-gf0bglm0	276	54	syndrome	syndrome	NN
cord-306424-gf0bglm0	276	55	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	276	56	open	open	JJ
cord-306424-gf0bglm0	276	57	reading	reading	NN
cord-306424-gf0bglm0	276	58	frame	frame	NN
cord-306424-gf0bglm0	276	59	(	(	-LRB-
cord-306424-gf0bglm0	276	60	ORF	ORF	NNP
cord-306424-gf0bglm0	276	61	)	)	-RRB-
cord-306424-gf0bglm0	276	62	3b	3b	NNP
cord-306424-gf0bglm0	276	63	,	,	,
cord-306424-gf0bglm0	276	64	ORF	ORF	NNP
cord-306424-gf0bglm0	276	65	6	6	CD
cord-306424-gf0bglm0	276	66	,	,	,
cord-306424-gf0bglm0	276	67	and	and	CC
cord-306424-gf0bglm0	276	68	nucleocapsid	nucleocapsid	NN
cord-306424-gf0bglm0	276	69	proteins	protein	NNS
cord-306424-gf0bglm0	276	70	function	function	VBP
cord-306424-gf0bglm0	276	71	as	as	IN
cord-306424-gf0bglm0	276	72	interferon	interferon	NN
cord-306424-gf0bglm0	276	73	antagonists	antagonist	NNS
cord-306424-gf0bglm0	277	1	The	the	DT
cord-306424-gf0bglm0	277	2	structural	structural	JJ
cord-306424-gf0bglm0	277	3	and	and	CC
cord-306424-gf0bglm0	277	4	accessory	accessory	NN
cord-306424-gf0bglm0	277	5	proteins	protein	NNS
cord-306424-gf0bglm0	277	6	M	M	NNP
cord-306424-gf0bglm0	277	7	,	,	,
cord-306424-gf0bglm0	277	8	ORF	ORF	NNP
cord-306424-gf0bglm0	277	9	4a	4a	CD
cord-306424-gf0bglm0	277	10	,	,	,
cord-306424-gf0bglm0	277	11	ORF	ORF	NNP
cord-306424-gf0bglm0	277	12	4b	4b	NNS
cord-306424-gf0bglm0	277	13	,	,	,
cord-306424-gf0bglm0	277	14	and	and	CC
cord-306424-gf0bglm0	277	15	ORF	ORF	NNP
cord-306424-gf0bglm0	277	16	5	5	CD
cord-306424-gf0bglm0	277	17	of	of	IN
cord-306424-gf0bglm0	277	18	Middle	Middle	NNP
cord-306424-gf0bglm0	277	19	East	East	NNP
cord-306424-gf0bglm0	277	20	respiratory	respiratory	JJ
cord-306424-gf0bglm0	277	21	syndrome	syndrome	NN
cord-306424-gf0bglm0	277	22	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	277	23	(	(	-LRB-
cord-306424-gf0bglm0	277	24	MERS	MERS	NNP
cord-306424-gf0bglm0	277	25	-	-	HYPH
cord-306424-gf0bglm0	277	26	CoV	CoV	NNP
cord-306424-gf0bglm0	277	27	)	)	-RRB-
cord-306424-gf0bglm0	277	28	are	be	VBP
cord-306424-gf0bglm0	277	29	potent	potent	JJ
cord-306424-gf0bglm0	277	30	interferon	interferon	NN
cord-306424-gf0bglm0	277	31	antagonists	antagonist	NNS
cord-306424-gf0bglm0	278	1	Transcriptional	transcriptional	JJ
cord-306424-gf0bglm0	278	2	upregulation	upregulation	NN
cord-306424-gf0bglm0	278	3	of	of	IN
cord-306424-gf0bglm0	278	4	SOCS	SOCS	NNP
cord-306424-gf0bglm0	278	5	1	1	CD
cord-306424-gf0bglm0	278	6	and	and	CC
cord-306424-gf0bglm0	278	7	suppressors	suppressor	NNS
cord-306424-gf0bglm0	278	8	of	of	IN
cord-306424-gf0bglm0	278	9	cytokine	cytokine	NN
cord-306424-gf0bglm0	278	10	signaling	signal	VBG
cord-306424-gf0bglm0	278	11	3	3	CD
cord-306424-gf0bglm0	278	12	mRNA	mrna	NN
cord-306424-gf0bglm0	278	13	in	in	IN
cord-306424-gf0bglm0	278	14	the	the	DT
cord-306424-gf0bglm0	278	15	absence	absence	NN
cord-306424-gf0bglm0	278	16	of	of	IN
cord-306424-gf0bglm0	278	17	suppressors	suppressor	NNS
cord-306424-gf0bglm0	278	18	of	of	IN
cord-306424-gf0bglm0	278	19	cytokine	cytokine	NN
cord-306424-gf0bglm0	278	20	signaling	signal	VBG
cord-306424-gf0bglm0	278	21	2	2	CD
cord-306424-gf0bglm0	278	22	mRNA	mrna	NN
cord-306424-gf0bglm0	278	23	after	after	IN
cord-306424-gf0bglm0	278	24	infection	infection	NN
cord-306424-gf0bglm0	278	25	with	with	IN
cord-306424-gf0bglm0	278	26	West	West	NNP
cord-306424-gf0bglm0	278	27	Nile	Nile	NNP
cord-306424-gf0bglm0	278	28	virus	virus	NN
cord-306424-gf0bglm0	278	29	or	or	CC
cord-306424-gf0bglm0	278	30	tick	tick	VB
cord-306424-gf0bglm0	278	31	-	-	HYPH
cord-306424-gf0bglm0	278	32	borne	bear	VBN
cord-306424-gf0bglm0	278	33	encephalitis	encephalitis	JJ
cord-306424-gf0bglm0	278	34	virus	virus	NN
cord-306424-gf0bglm0	278	35	,	,	,
cord-306424-gf0bglm0	278	36	Vector	Vector	NNP
cord-306424-gf0bglm0	278	37	Borne	Borne	NNP
cord-306424-gf0bglm0	278	38	Zoonotic	Zoonotic	NNP
cord-306424-gf0bglm0	278	39	Dis	Dis	NNP
cord-306424-gf0bglm0	278	40	Expression	expression	NN
cord-306424-gf0bglm0	278	41	profile	profile	NN
cord-306424-gf0bglm0	278	42	of	of	IN
cord-306424-gf0bglm0	278	43	immune	immune	JJ
cord-306424-gf0bglm0	278	44	response	response	NN
cord-306424-gf0bglm0	278	45	genes	gene	NNS
cord-306424-gf0bglm0	278	46	during	during	IN
cord-306424-gf0bglm0	278	47	acute	acute	JJ
cord-306424-gf0bglm0	278	48	myopathy	myopathy	NN
cord-306424-gf0bglm0	278	49	induced	induce	VBN
cord-306424-gf0bglm0	278	50	by	by	IN
cord-306424-gf0bglm0	278	51	chikungunya	chikungunya	NN
cord-306424-gf0bglm0	278	52	virus	virus	NN
cord-306424-gf0bglm0	278	53	in	in	IN
cord-306424-gf0bglm0	278	54	a	a	DT
cord-306424-gf0bglm0	278	55	mouse	mouse	NN
cord-306424-gf0bglm0	278	56	model	model	NN
cord-306424-gf0bglm0	279	1	Japanese	japanese	JJ
cord-306424-gf0bglm0	279	2	encephalitis	encephalitis	RB
cord-306424-gf0bglm0	279	3	virus	virus	NN
cord-306424-gf0bglm0	279	4	infection	infection	NN
cord-306424-gf0bglm0	279	5	modulates	modulate	VBZ
cord-306424-gf0bglm0	279	6	the	the	DT
cord-306424-gf0bglm0	279	7	expression	expression	NN
cord-306424-gf0bglm0	279	8	of	of	IN
cord-306424-gf0bglm0	279	9	suppressors	suppressor	NNS
cord-306424-gf0bglm0	279	10	of	of	IN
cord-306424-gf0bglm0	279	11	cytokine	cytokine	NN
cord-306424-gf0bglm0	279	12	signaling	signaling	NN
cord-306424-gf0bglm0	279	13	(	(	-LRB-
cord-306424-gf0bglm0	279	14	SOCS	SOCS	NNP
cord-306424-gf0bglm0	279	15	)	)	-RRB-
cord-306424-gf0bglm0	279	16	in	in	IN
cord-306424-gf0bglm0	279	17	macrophages	macrophage	NNS
cord-306424-gf0bglm0	279	18	:	:	:
cord-306424-gf0bglm0	279	19	implications	implication	NNS
cord-306424-gf0bglm0	279	20	for	for	IN
cord-306424-gf0bglm0	279	21	the	the	DT
cord-306424-gf0bglm0	279	22	hosts	host	NNS
cord-306424-gf0bglm0	279	23	'	'	POS
cord-306424-gf0bglm0	279	24	innate	innate	JJ
cord-306424-gf0bglm0	279	25	immune	immune	JJ
cord-306424-gf0bglm0	279	26	response	response	NN
cord-306424-gf0bglm0	280	1	West	West	NNP
cord-306424-gf0bglm0	280	2	Nile	Nile	NNP
cord-306424-gf0bglm0	280	3	virus	virus	NN
cord-306424-gf0bglm0	280	4	inhibits	inhibit	VBZ
cord-306424-gf0bglm0	280	5	the	the	DT
cord-306424-gf0bglm0	280	6	signal	signal	NN
cord-306424-gf0bglm0	280	7	transduction	transduction	NN
cord-306424-gf0bglm0	280	8	pathway	pathway	NN
cord-306424-gf0bglm0	280	9	of	of	IN
cord-306424-gf0bglm0	280	10	alpha	alpha	NN
cord-306424-gf0bglm0	280	11	interferon	interferon	NN
cord-306424-gf0bglm0	280	12	Blocking	blocking	NN
cord-306424-gf0bglm0	280	13	of	of	IN
cord-306424-gf0bglm0	280	14	interferon	interferon	NN
cord-306424-gf0bglm0	280	15	-	-	HYPH
cord-306424-gf0bglm0	280	16	induced	induce	VBN
cord-306424-gf0bglm0	280	17	Jak	Jak	NNP
cord-306424-gf0bglm0	280	18	-	-	HYPH
cord-306424-gf0bglm0	280	19	Stat	Stat	NNP
cord-306424-gf0bglm0	280	20	signaling	signaling	NN
cord-306424-gf0bglm0	280	21	by	by	IN
cord-306424-gf0bglm0	280	22	Japanese	japanese	JJ
cord-306424-gf0bglm0	280	23	encephalitis	encephalitis	RB
cord-306424-gf0bglm0	280	24	virus	virus	NN
cord-306424-gf0bglm0	280	25	NS5	ns5	JJ
cord-306424-gf0bglm0	280	26	through	through	IN
cord-306424-gf0bglm0	280	27	a	a	DT
cord-306424-gf0bglm0	280	28	protein	protein	NN
cord-306424-gf0bglm0	280	29	tyrosine	tyrosine	NN
cord-306424-gf0bglm0	280	30	phosphatase	phosphatase	NN
cord-306424-gf0bglm0	280	31	-	-	HYPH
cord-306424-gf0bglm0	280	32	mediated	mediate	VBN
cord-306424-gf0bglm0	280	33	mechanism	mechanism	NN
cord-306424-gf0bglm0	281	1	Severe	severe	JJ
cord-306424-gf0bglm0	281	2	acute	acute	JJ
cord-306424-gf0bglm0	281	3	respiratory	respiratory	JJ
cord-306424-gf0bglm0	281	4	syndrome	syndrome	NN
cord-306424-gf0bglm0	281	5	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	281	6	evades	evade	VBZ
cord-306424-gf0bglm0	281	7	antiviral	antiviral	JJ
cord-306424-gf0bglm0	281	8	signaling	signaling	NN
cord-306424-gf0bglm0	281	9	:	:	:
cord-306424-gf0bglm0	281	10	role	role	NN
cord-306424-gf0bglm0	281	11	of	of	IN
cord-306424-gf0bglm0	281	12	nsp1	nsp1	NNS
cord-306424-gf0bglm0	281	13	and	and	CC
cord-306424-gf0bglm0	281	14	rational	rational	JJ
cord-306424-gf0bglm0	281	15	design	design	NN
cord-306424-gf0bglm0	281	16	of	of	IN
cord-306424-gf0bglm0	281	17	an	an	DT
cord-306424-gf0bglm0	281	18	attenuated	attenuated	JJ
cord-306424-gf0bglm0	281	19	strain	strain	NN
cord-306424-gf0bglm0	281	20	Severe	severe	JJ
cord-306424-gf0bglm0	281	21	acute	acute	JJ
cord-306424-gf0bglm0	281	22	respiratory	respiratory	JJ
cord-306424-gf0bglm0	281	23	syndrome	syndrome	NN
cord-306424-gf0bglm0	281	24	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	281	25	ORF6	ORF6	NNP
cord-306424-gf0bglm0	281	26	antagonizes	antagonize	VBZ
cord-306424-gf0bglm0	281	27	STAT1	stat1	NN
cord-306424-gf0bglm0	281	28	function	function	NN
cord-306424-gf0bglm0	281	29	by	by	IN
cord-306424-gf0bglm0	281	30	sequestering	sequester	VBG
cord-306424-gf0bglm0	281	31	nuclear	nuclear	JJ
cord-306424-gf0bglm0	281	32	import	import	NN
cord-306424-gf0bglm0	281	33	factors	factor	NNS
cord-306424-gf0bglm0	281	34	on	on	IN
cord-306424-gf0bglm0	281	35	the	the	DT
cord-306424-gf0bglm0	281	36	rough	rough	JJ
cord-306424-gf0bglm0	281	37	endoplasmic	endoplasmic	NN
cord-306424-gf0bglm0	281	38	reticulum	reticulum	NN
cord-306424-gf0bglm0	281	39	/	/	SYM
cord-306424-gf0bglm0	281	40	Golgi	Golgi	NNP
cord-306424-gf0bglm0	281	41	membrane	membrane	NN
cord-306424-gf0bglm0	281	42	Severe	severe	JJ
cord-306424-gf0bglm0	281	43	acute	acute	JJ
cord-306424-gf0bglm0	281	44	respiratory	respiratory	JJ
cord-306424-gf0bglm0	281	45	syndrome	syndrome	NN
cord-306424-gf0bglm0	281	46	coronavirus	coronavirus	NN
cord-306424-gf0bglm0	281	47	papain	papain	NN
cord-306424-gf0bglm0	281	48	-	-	HYPH
cord-306424-gf0bglm0	281	49	like	like	JJ
cord-306424-gf0bglm0	281	50	protease	protease	NN
cord-306424-gf0bglm0	281	51	suppressed	suppress	VBN
cord-306424-gf0bglm0	281	52	alpha	alpha	NN
cord-306424-gf0bglm0	281	53	interferon	interferon	NN
cord-306424-gf0bglm0	281	54	-	-	HYPH
cord-306424-gf0bglm0	281	55	induced	induce	VBN
cord-306424-gf0bglm0	281	56	responses	response	NNS
cord-306424-gf0bglm0	281	57	through	through	IN
cord-306424-gf0bglm0	281	58	downregulation	downregulation	NN
cord-306424-gf0bglm0	281	59	of	of	IN
cord-306424-gf0bglm0	281	60	extracellular	extracellular	JJ
cord-306424-gf0bglm0	281	61	signal	signal	NN
cord-306424-gf0bglm0	281	62	-	-	HYPH
cord-306424-gf0bglm0	281	63	regulated	regulate	VBN
cord-306424-gf0bglm0	281	64	kinase	kinase	NN
cord-306424-gf0bglm0	281	65	1-mediated	1-mediated	CD
cord-306424-gf0bglm0	281	66	signalling	signal	VBG
cord-306424-gf0bglm0	281	67	pathways	pathway	NNS
cord-306424-gf0bglm0	282	1	Inhibition	inhibition	NN
cord-306424-gf0bglm0	282	2	of	of	IN
cord-306424-gf0bglm0	282	3	cytoplasmic	cytoplasmic	JJ
cord-306424-gf0bglm0	282	4	mRNA	mRNA	NNP
cord-306424-gf0bglm0	282	5	stress	stress	NN
cord-306424-gf0bglm0	282	6	granule	granule	NN
cord-306424-gf0bglm0	282	7	formation	formation	NN
cord-306424-gf0bglm0	282	8	by	by	IN
cord-306424-gf0bglm0	282	9	a	a	DT
cord-306424-gf0bglm0	282	10	viral	viral	JJ
cord-306424-gf0bglm0	282	11	proteinase	proteinase	NN
cord-306424-gf0bglm0	282	12	Hepatitis	hepatitis	NN
cord-306424-gf0bglm0	282	13	C	C	NNP
cord-306424-gf0bglm0	282	14	virus	virus	NN
cord-306424-gf0bglm0	282	15	(	(	-LRB-
cord-306424-gf0bglm0	282	16	HCV	HCV	NNP
cord-306424-gf0bglm0	282	17	)	)	-RRB-
cord-306424-gf0bglm0	282	18	induces	induce	VBZ
cord-306424-gf0bglm0	282	19	formation	formation	NN
cord-306424-gf0bglm0	282	20	of	of	IN
cord-306424-gf0bglm0	282	21	stress	stress	NN
cord-306424-gf0bglm0	282	22	granules	granule	NNS
cord-306424-gf0bglm0	282	23	whose	whose	WP$
cord-306424-gf0bglm0	282	24	proteins	protein	NNS
cord-306424-gf0bglm0	282	25	regulate	regulate	VBP
cord-306424-gf0bglm0	282	26	HCV	HCV	NNP
cord-306424-gf0bglm0	282	27	RNA	RNA	NNP
cord-306424-gf0bglm0	282	28	replication	replication	NN
cord-306424-gf0bglm0	282	29	and	and	CC
cord-306424-gf0bglm0	282	30	virus	virus	NN
cord-306424-gf0bglm0	282	31	assembly	assembly	NN
cord-306424-gf0bglm0	282	32	and	and	CC
cord-306424-gf0bglm0	282	33	egress	egress	NN
cord-306424-gf0bglm0	282	34	Japanese	japanese	JJ
cord-306424-gf0bglm0	282	35	encephalitis	encephalitis	RB
cord-306424-gf0bglm0	282	36	virus	virus	NN
cord-306424-gf0bglm0	282	37	core	core	NN
cord-306424-gf0bglm0	282	38	protein	protein	NN
cord-306424-gf0bglm0	282	39	inhibits	inhibit	VBZ
cord-306424-gf0bglm0	282	40	stress	stress	NN
cord-306424-gf0bglm0	282	41	granule	granule	NN
cord-306424-gf0bglm0	282	42	formation	formation	NN
cord-306424-gf0bglm0	282	43	through	through	IN
cord-306424-gf0bglm0	282	44	an	an	DT
cord-306424-gf0bglm0	282	45	interaction	interaction	NN
cord-306424-gf0bglm0	282	46	with	with	IN
cord-306424-gf0bglm0	282	47	Caprin-1	Caprin-1	NNP
cord-306424-gf0bglm0	282	48	and	and	CC
cord-306424-gf0bglm0	282	49	facilitates	facilitate	VBZ
cord-306424-gf0bglm0	282	50	viral	viral	JJ
cord-306424-gf0bglm0	282	51	propagation	propagation	NN
cord-306424-gf0bglm0	282	52	Interaction	Interaction	NNP
cord-306424-gf0bglm0	282	53	of	of	IN
cord-306424-gf0bglm0	282	54	TIA-1	TIA-1	NNP
cord-306424-gf0bglm0	283	1	/TIAR	/TIAR	NFP
cord-306424-gf0bglm0	283	2	with	with	IN
cord-306424-gf0bglm0	283	3	West	West	NNP
cord-306424-gf0bglm0	283	4	Nile	Nile	NNP
cord-306424-gf0bglm0	283	5	and	and	CC
cord-306424-gf0bglm0	283	6	dengue	dengue	NN
cord-306424-gf0bglm0	283	7	virus	virus	NN
cord-306424-gf0bglm0	283	8	products	product	NNS
cord-306424-gf0bglm0	283	9	in	in	IN
cord-306424-gf0bglm0	283	10	infected	infected	JJ
cord-306424-gf0bglm0	283	11	cells	cell	NNS
cord-306424-gf0bglm0	283	12	interferes	interfere	VBZ
cord-306424-gf0bglm0	283	13	with	with	IN
cord-306424-gf0bglm0	284	1	stress	stress	NN
cord-306424-gf0bglm0	284	2	granule	granule	NN
cord-306424-gf0bglm0	284	3	formation	formation	NN
cord-306424-gf0bglm0	284	4	and	and	CC
cord-306424-gf0bglm0	284	5	processing	processing	NN
cord-306424-gf0bglm0	284	6	body	body	NN
cord-306424-gf0bglm0	284	7	assembly	assembly	NN
cord-306424-gf0bglm0	284	8	Dynamic	dynamic	JJ
cord-306424-gf0bglm0	284	9	oscillation	oscillation	NN
cord-306424-gf0bglm0	284	10	of	of	IN
cord-306424-gf0bglm0	284	11	translation	translation	NN
cord-306424-gf0bglm0	284	12	and	and	CC
cord-306424-gf0bglm0	284	13	stress	stress	NN
cord-306424-gf0bglm0	284	14	granule	granule	NN
cord-306424-gf0bglm0	284	15	formation	formation	NN
cord-306424-gf0bglm0	284	16	mark	mark	VBP
cord-306424-gf0bglm0	284	17	the	the	DT
cord-306424-gf0bglm0	284	18	cellular	cellular	JJ
cord-306424-gf0bglm0	284	19	response	response	NN
cord-306424-gf0bglm0	284	20	to	to	IN
cord-306424-gf0bglm0	284	21	virus	virus	NN
cord-306424-gf0bglm0	284	22	infection	infection	NN
cord-306424-gf0bglm0	284	23	Stress	Stress	NNP
cord-306424-gf0bglm0	284	24	granule	granule	NN
cord-306424-gf0bglm0	284	25	components	component	NNS
cord-306424-gf0bglm0	284	26	G3BP1	G3BP1	NNP
cord-306424-gf0bglm0	284	27	and	and	CC
cord-306424-gf0bglm0	284	28	G3BP2	G3BP2	NNP
cord-306424-gf0bglm0	285	1	play	play	VB
cord-306424-gf0bglm0	285	2	a	a	DT
cord-306424-gf0bglm0	285	3	proviral	proviral	JJ
cord-306424-gf0bglm0	285	4	role	role	NN
cord-306424-gf0bglm0	285	5	early	early	RB
cord-306424-gf0bglm0	285	6	in	in	IN
cord-306424-gf0bglm0	285	7	Chikungunya	Chikungunya	NNP
cord-306424-gf0bglm0	285	8	virus	virus	NN
cord-306424-gf0bglm0	285	9	replication	replication	NN
cord-306424-gf0bglm0	286	1	Middle	middle	JJ
cord-306424-gf0bglm0	286	2	east	east	NNP
cord-306424-gf0bglm0	286	3	respiratory	respiratory	JJ
cord-306424-gf0bglm0	286	4	Coronavirus	Coronavirus	NNP
cord-306424-gf0bglm0	286	5	accessory	accessory	NN
cord-306424-gf0bglm0	286	6	protein	protein	NN
cord-306424-gf0bglm0	286	7	4a	4a	CD
cord-306424-gf0bglm0	286	8	inhibits	inhibit	VBZ
cord-306424-gf0bglm0	286	9	PKR	PKR	NNP
cord-306424-gf0bglm0	286	10	-	-	HYPH
cord-306424-gf0bglm0	286	11	Mediated	mediate	VBN
cord-306424-gf0bglm0	286	12	antiviral	antiviral	JJ
cord-306424-gf0bglm0	286	13	stress	stress	NN
cord-306424-gf0bglm0	286	14	responses	response	NNS
cord-306424-gf0bglm0	286	15	Dengue	dengue	NN
cord-306424-gf0bglm0	286	16	virus	virus	NN
cord-306424-gf0bglm0	286	17	perturbs	perturb	VBZ
cord-306424-gf0bglm0	286	18	mitochondrial	mitochondrial	JJ
cord-306424-gf0bglm0	286	19	morphodynamics	morphodynamic	NNS
cord-306424-gf0bglm0	286	20	to	to	TO
cord-306424-gf0bglm0	286	21	dampen	dampen	VB
cord-306424-gf0bglm0	286	22	innate	innate	JJ
cord-306424-gf0bglm0	286	23	immune	immune	JJ
cord-306424-gf0bglm0	286	24	responses	response	NNS
cord-306424-gf0bglm0	287	1	The	the	DT
cord-306424-gf0bglm0	287	2	hepatitis	hepatitis	NN
cord-306424-gf0bglm0	287	3	C	c	NN
cord-306424-gf0bglm0	287	4	virus	virus	NN
cord-306424-gf0bglm0	287	5	-	-	HYPH
cord-306424-gf0bglm0	287	6	induced	induce	VBN
cord-306424-gf0bglm0	287	7	membranous	membranous	JJ
cord-306424-gf0bglm0	287	8	web	web	NN
cord-306424-gf0bglm0	287	9	and	and	CC
cord-306424-gf0bglm0	287	10	associated	associate	VBN
cord-306424-gf0bglm0	287	11	nuclear	nuclear	JJ
cord-306424-gf0bglm0	287	12	transport	transport	NN
cord-306424-gf0bglm0	287	13	machinery	machinery	NN
cord-306424-gf0bglm0	287	14	limit	limit	VBP
cord-306424-gf0bglm0	287	15	access	access	NN
cord-306424-gf0bglm0	287	16	of	of	IN
cord-306424-gf0bglm0	287	17	pattern	pattern	NN
cord-306424-gf0bglm0	287	18	recognition	recognition	NN
cord-306424-gf0bglm0	287	19	receptors	receptor	NNS
cord-306424-gf0bglm0	287	20	to	to	IN
cord-306424-gf0bglm0	287	21	viral	viral	JJ
cord-306424-gf0bglm0	287	22	replication	replication	NN
cord-306424-gf0bglm0	287	23	sites	site	NNS
cord-306424-gf0bglm0	288	1	Interferon	interferon	NN
cord-306424-gf0bglm0	288	2	-	-	HYPH
cord-306424-gf0bglm0	288	3	inducible	inducible	JJ
cord-306424-gf0bglm0	289	1	cholesterol-25-hydroxylase	cholesterol-25-hydroxylase	NNP
cord-306424-gf0bglm0	289	2	restricts	restrict	VBZ
cord-306424-gf0bglm0	289	3	hepatitis	hepatitis	NN
cord-306424-gf0bglm0	289	4	C	c	NN
cord-306424-gf0bglm0	289	5	virus	virus	NN
cord-306424-gf0bglm0	289	6	replication	replication	NN
cord-306424-gf0bglm0	289	7	through	through	IN
cord-306424-gf0bglm0	289	8	blockage	blockage	NN
cord-306424-gf0bglm0	289	9	of	of	IN
cord-306424-gf0bglm0	289	10	membranous	membranous	JJ
cord-306424-gf0bglm0	289	11	web	web	NN
cord-306424-gf0bglm0	289	12	formation	formation	NN
cord-306424-gf0bglm0	290	1	The	the	DT
cord-306424-gf0bglm0	290	2	antiviral	antiviral	JJ
cord-306424-gf0bglm0	290	3	protein	protein	NN
cord-306424-gf0bglm0	290	4	viperin	viperin	NNP
cord-306424-gf0bglm0	290	5	inhibits	inhibit	VBZ
cord-306424-gf0bglm0	290	6	hepatitis	hepatitis	NNP
cord-306424-gf0bglm0	290	7	C	C	NNP
cord-306424-gf0bglm0	290	8	virus	virus	NN
cord-306424-gf0bglm0	290	9	replication	replication	NN
cord-306424-gf0bglm0	290	10	via	via	IN
cord-306424-gf0bglm0	290	11	interaction	interaction	NN
cord-306424-gf0bglm0	290	12	with	with	IN
cord-306424-gf0bglm0	290	13	nonstructural	nonstructural	JJ
cord-306424-gf0bglm0	290	14	protein	protein	NN
cord-306424-gf0bglm0	290	15	5A	5a	CD
cord-306424-gf0bglm0	290	16	Antiviral	antiviral	JJ
cord-306424-gf0bglm0	290	17	innate	innate	VBP
cord-306424-gf0bglm0	290	18	immune	immune	JJ
cord-306424-gf0bglm0	290	19	response	response	NN
cord-306424-gf0bglm0	290	20	interferes	interfere	VBZ
cord-306424-gf0bglm0	290	21	with	with	IN
cord-306424-gf0bglm0	290	22	the	the	DT
cord-306424-gf0bglm0	290	23	formation	formation	NN
cord-306424-gf0bglm0	290	24	of	of	IN
cord-306424-gf0bglm0	290	25	replication	replication	NN
cord-306424-gf0bglm0	290	26	-	-	HYPH
cord-306424-gf0bglm0	290	27	associated	associate	VBN
cord-306424-gf0bglm0	290	28	membrane	membrane	NN
cord-306424-gf0bglm0	290	29	structures	structure	NNS
cord-306424-gf0bglm0	290	30	induced	induce	VBN
cord-306424-gf0bglm0	290	31	by	by	IN
cord-306424-gf0bglm0	290	32	a	a	DT
cord-306424-gf0bglm0	290	33	+	+	CC
cord-306424-gf0bglm0	290	34	RNA	RNA	NNP
cord-306424-gf0bglm0	290	35	virus	virus	NN
cord-306424-gf0bglm0	290	36	Self	self	NN
cord-306424-gf0bglm0	290	37	and	and	CC
cord-306424-gf0bglm0	290	38	non	non	JJ
cord-306424-gf0bglm0	290	39	-	-	JJ
cord-306424-gf0bglm0	290	40	self	self	JJ
cord-306424-gf0bglm0	290	41	discrimination	discrimination	NN
cord-306424-gf0bglm0	290	42	of	of	IN
cord-306424-gf0bglm0	290	43	intracellular	intracellular	JJ
cord-306424-gf0bglm0	290	44	membranes	membrane	NNS
cord-306424-gf0bglm0	290	45	by	by	IN
cord-306424-gf0bglm0	290	46	the	the	DT
cord-306424-gf0bglm0	290	47	innate	innate	JJ
cord-306424-gf0bglm0	290	48	immune	immune	JJ
cord-306424-gf0bglm0	290	49	system	system	NN
cord-306424-gf0bglm0	291	1	Interferon	interferon	NN
cord-306424-gf0bglm0	291	2	-	-	HYPH
cord-306424-gf0bglm0	291	3	inducible	inducible	JJ
cord-306424-gf0bglm0	291	4	GTPases	gtpase	NNS
cord-306424-gf0bglm0	291	5	in	in	IN
cord-306424-gf0bglm0	291	6	host	host	NN
cord-306424-gf0bglm0	291	7	resistance	resistance	NN
cord-306424-gf0bglm0	291	8	,	,	,
cord-306424-gf0bglm0	291	9	inflammation	inflammation	NN
cord-306424-gf0bglm0	291	10	and	and	CC
cord-306424-gf0bglm0	291	11	disease	disease	NN
cord-306424-gf0bglm0	291	12	IFN	IFN	NNP
cord-306424-gf0bglm0	291	13	-	-	HYPH
cord-306424-gf0bglm0	291	14	inducible	inducible	JJ
cord-306424-gf0bglm0	291	15	GTPases	gtpase	NNS
cord-306424-gf0bglm0	291	16	in	in	IN
cord-306424-gf0bglm0	291	17	host	host	NN
cord-306424-gf0bglm0	291	18	cell	cell	NN
cord-306424-gf0bglm0	291	19	defense	defense	NN
cord-306424-gf0bglm0	291	20	IRG	IRG	NNP
cord-306424-gf0bglm0	291	21	and	and	CC
cord-306424-gf0bglm0	291	22	GBP	GBP	NNP
cord-306424-gf0bglm0	291	23	host	host	NN
cord-306424-gf0bglm0	291	24	resistance	resistance	NN
cord-306424-gf0bglm0	291	25	factors	factor	NNS
cord-306424-gf0bglm0	292	1	target	target	VB
cord-306424-gf0bglm0	292	2	aberrant	aberrant	JJ
cord-306424-gf0bglm0	292	3	,	,	,
cord-306424-gf0bglm0	292	4	non	non	JJ
cord-306424-gf0bglm0	292	5	-	-	JJ
cord-306424-gf0bglm0	292	6	self	self	JJ
cord-306424-gf0bglm0	292	7	vacuoles	vacuole	NNS
cord-306424-gf0bglm0	292	8	characterized	characterize	VBN
cord-306424-gf0bglm0	292	9	by	by	IN
cord-306424-gf0bglm0	292	10	the	the	DT
cord-306424-gf0bglm0	292	11	missing	missing	NN
cord-306424-gf0bglm0	292	12	of	of	IN
cord-306424-gf0bglm0	292	13	self	self	NN
cord-306424-gf0bglm0	292	14	IRGM	IRGM	NNP
cord-306424-gf0bglm0	292	15	proteins	protein	VBZ
cord-306424-gf0bglm0	292	16	Chlamydia	Chlamydia	NNP
cord-306424-gf0bglm0	292	17	muridarum	muridarum	NN
cord-306424-gf0bglm0	292	18	evades	evade	VBZ
cord-306424-gf0bglm0	292	19	growth	growth	NN
cord-306424-gf0bglm0	292	20	restriction	restriction	NN
cord-306424-gf0bglm0	292	21	by	by	IN
cord-306424-gf0bglm0	292	22	the	the	DT
cord-306424-gf0bglm0	292	23	IFN	IFN	NNP
cord-306424-gf0bglm0	292	24	-	-	HYPH
cord-306424-gf0bglm0	292	25	gamma	gamma	NN
cord-306424-gf0bglm0	292	26	-	-	HYPH
cord-306424-gf0bglm0	292	27	inducible	inducible	JJ
cord-306424-gf0bglm0	292	28	host	host	NN
cord-306424-gf0bglm0	292	29	resistance	resistance	NN
cord-306424-gf0bglm0	292	30	factor	factor	NN
cord-306424-gf0bglm0	292	31	Irgb10	Irgb10	NNP
cord-306424-gf0bglm0	292	32	Identification	Identification	NNP
cord-306424-gf0bglm0	292	33	of	of	IN
cord-306424-gf0bglm0	292	34	the	the	DT
cord-306424-gf0bglm0	292	35	microsporidian	microsporidian	NNP
cord-306424-gf0bglm0	292	36	encephalitozoon	encephalitozoon	NNP
cord-306424-gf0bglm0	292	37	cuniculi	cuniculi	NNP
cord-306424-gf0bglm0	292	38	as	as	IN
cord-306424-gf0bglm0	292	39	a	a	DT
cord-306424-gf0bglm0	292	40	new	new	JJ
cord-306424-gf0bglm0	292	41	target	target	NN
cord-306424-gf0bglm0	292	42	of	of	IN
cord-306424-gf0bglm0	292	43	the	the	DT
cord-306424-gf0bglm0	292	44	IFN	IFN	NNP
cord-306424-gf0bglm0	292	45	-	-	HYPH
cord-306424-gf0bglm0	292	46	g	g	NNP
cord-306424-gf0bglm0	292	47	inducible	inducible	JJ
cord-306424-gf0bglm0	292	48	IRG	IRG	NNP
cord-306424-gf0bglm0	292	49	resistance	resistance	NN
cord-306424-gf0bglm0	292	50	system	system	NN
cord-306424-gf0bglm0	293	1	The	the	DT
cord-306424-gf0bglm0	293	2	IRG	IRG	NNP
cord-306424-gf0bglm0	293	3	protein	protein	NN
cord-306424-gf0bglm0	293	4	-	-	HYPH
cord-306424-gf0bglm0	293	5	based	base	VBN
cord-306424-gf0bglm0	293	6	resistance	resistance	NN
cord-306424-gf0bglm0	293	7	mechanism	mechanism	NN
cord-306424-gf0bglm0	293	8	in	in	IN
cord-306424-gf0bglm0	293	9	mice	mouse	NNS
cord-306424-gf0bglm0	293	10	and	and	CC
cord-306424-gf0bglm0	293	11	its	-PRON-	PRP$
cord-306424-gf0bglm0	293	12	relation	relation	NN
cord-306424-gf0bglm0	293	13	to	to	IN
cord-306424-gf0bglm0	293	14	virulence	virulence	NN
cord-306424-gf0bglm0	293	15	in	in	IN
cord-306424-gf0bglm0	293	16	Toxoplasma	toxoplasma	NN
cord-306424-gf0bglm0	293	17	gondii	gondii	NN
cord-306424-gf0bglm0	293	18	Autophagosome	Autophagosome	NNP
cord-306424-gf0bglm0	293	19	-	-	HYPH
cord-306424-gf0bglm0	293	20	independent	independent	JJ
cord-306424-gf0bglm0	293	21	essential	essential	JJ
cord-306424-gf0bglm0	293	22	function	function	NN
cord-306424-gf0bglm0	293	23	for	for	IN
cord-306424-gf0bglm0	293	24	the	the	DT
cord-306424-gf0bglm0	293	25	autophagy	autophagy	NN
cord-306424-gf0bglm0	293	26	protein	protein	NN
cord-306424-gf0bglm0	293	27	atg5	atg5	RB
cord-306424-gf0bglm0	293	28	in	in	IN
cord-306424-gf0bglm0	293	29	cellular	cellular	JJ
cord-306424-gf0bglm0	293	30	immunity	immunity	NN
cord-306424-gf0bglm0	293	31	to	to	IN
cord-306424-gf0bglm0	293	32	intracellular	intracellular	JJ
cord-306424-gf0bglm0	293	33	pathogens	pathogen	NNS
cord-306424-gf0bglm0	294	1	The	the	DT
cord-306424-gf0bglm0	294	2	parasitophorous	parasitophorous	JJ
cord-306424-gf0bglm0	294	3	vacuole	vacuole	NN
cord-306424-gf0bglm0	294	4	membrane	membrane	NN
cord-306424-gf0bglm0	294	5	of	of	IN
cord-306424-gf0bglm0	294	6	toxoplasma	toxoplasma	NN
cord-306424-gf0bglm0	294	7	gondii	gondii	NNP
cord-306424-gf0bglm0	294	8	is	be	VBZ
cord-306424-gf0bglm0	294	9	targeted	target	VBN
cord-306424-gf0bglm0	294	10	for	for	IN
cord-306424-gf0bglm0	294	11	disruption	disruption	NN
cord-306424-gf0bglm0	294	12	by	by	IN
cord-306424-gf0bglm0	294	13	ubiquitin	ubiquitin	NN
cord-306424-gf0bglm0	294	14	-	-	HYPH
cord-306424-gf0bglm0	294	15	like	like	JJ
cord-306424-gf0bglm0	294	16	conjugation	conjugation	NN
cord-306424-gf0bglm0	294	17	systems	system	NNS
cord-306424-gf0bglm0	294	18	of	of	IN
cord-306424-gf0bglm0	294	19	autophagy	autophagy	NN
cord-306424-gf0bglm0	295	1	Interferon	interferon	NN
cord-306424-gf0bglm0	295	2	-	-	HYPH
cord-306424-gf0bglm0	295	3	inducible	inducible	JJ
cord-306424-gf0bglm0	295	4	GTPases	gtpase	NNS
cord-306424-gf0bglm0	295	5	go	go	VBP
cord-306424-gf0bglm0	295	6	to	to	IN
cord-306424-gf0bglm0	295	7	their	-PRON-	PRP$
cord-306424-gf0bglm0	295	8	target	target	NN
cord-306424-gf0bglm0	295	9	membranes	membrane	NNS
cord-306424-gf0bglm0	295	10	via	via	IN
cord-306424-gf0bglm0	295	11	the	the	DT
cord-306424-gf0bglm0	295	12	LC3-conjugation	lc3-conjugation	NN
cord-306424-gf0bglm0	295	13	system	system	NN
cord-306424-gf0bglm0	295	14	of	of	IN
cord-306424-gf0bglm0	295	15	autophagy	autophagy	NN
cord-306424-gf0bglm0	295	16	Targeting	target	VBG
cord-306424-gf0bglm0	295	17	by	by	IN
cord-306424-gf0bglm0	295	18	AutophaGy	AutophaGy	NNP
cord-306424-gf0bglm0	295	19	proteins	protein	NNS
cord-306424-gf0bglm0	295	20	(	(	-LRB-
cord-306424-gf0bglm0	295	21	TAG	tag	NN
cord-306424-gf0bglm0	295	22	)	)	-RRB-
cord-306424-gf0bglm0	295	23	:	:	:
cord-306424-gf0bglm0	296	1	Targeting	target	VBG
cord-306424-gf0bglm0	296	2	of	of	IN
cord-306424-gf0bglm0	296	3	IFNG	ifng	NN
cord-306424-gf0bglm0	296	4	-	-	HYPH
cord-306424-gf0bglm0	296	5	inducible	inducible	JJ
cord-306424-gf0bglm0	296	6	GTPases	gtpase	NNS
cord-306424-gf0bglm0	296	7	to	to	IN
cord-306424-gf0bglm0	296	8	membranes	membrane	NNS
cord-306424-gf0bglm0	296	9	by	by	IN
cord-306424-gf0bglm0	296	10	the	the	DT
cord-306424-gf0bglm0	296	11	LC3	lc3	JJ
cord-306424-gf0bglm0	296	12	conjugation	conjugation	NN
cord-306424-gf0bglm0	296	13	system	system	NN
cord-306424-gf0bglm0	296	14	of	of	IN
cord-306424-gf0bglm0	296	15	autophagy	autophagy	NN
cord-306424-gf0bglm0	296	16	Dissection	dissection	NN
cord-306424-gf0bglm0	296	17	of	of	IN
cord-306424-gf0bglm0	296	18	the	the	DT
cord-306424-gf0bglm0	296	19	autophagosome	autophagosome	JJ
cord-306424-gf0bglm0	296	20	maturation	maturation	NN
cord-306424-gf0bglm0	296	21	process	process	NN
cord-306424-gf0bglm0	296	22	by	by	IN
cord-306424-gf0bglm0	296	23	a	a	DT
cord-306424-gf0bglm0	296	24	novel	novel	JJ
cord-306424-gf0bglm0	296	25	reporter	reporter	NN
cord-306424-gf0bglm0	296	26	protein	protein	NN
cord-306424-gf0bglm0	296	27	,	,	,
cord-306424-gf0bglm0	296	28	tandem	tandem	NNP
cord-306424-gf0bglm0	296	29	fluorescenttagged	fluorescenttagge	VBN
cord-306424-gf0bglm0	297	1	LC3	LC3	NNP
cord-306424-gf0bglm0	297	2	Selective	selective	JJ
cord-306424-gf0bglm0	297	3	autophagy	autophagy	NN
cord-306424-gf0bglm0	297	4	against	against	IN
cord-306424-gf0bglm0	297	5	membranous	membranous	JJ
cord-306424-gf0bglm0	297	6	compartments	compartment	NNS
cord-306424-gf0bglm0	297	7	:	:	:
cord-306424-gf0bglm0	297	8	canonical	canonical	JJ
cord-306424-gf0bglm0	297	9	and	and	CC
cord-306424-gf0bglm0	297	10	unconventional	unconventional	JJ
cord-306424-gf0bglm0	297	11	purposes	purpose	NNS
cord-306424-gf0bglm0	297	12	and	and	CC
cord-306424-gf0bglm0	297	13	mechanisms	mechanism	NNS
cord-306424-gf0bglm0	297	14	Hidden	hide	VBN
cord-306424-gf0bglm0	297	15	behind	behind	IN
cord-306424-gf0bglm0	297	16	autophagy	autophagy	NN
cord-306424-gf0bglm0	297	17	:	:	:
cord-306424-gf0bglm0	298	1	the	the	DT
cord-306424-gf0bglm0	298	2	unconventional	unconventional	JJ
cord-306424-gf0bglm0	298	3	roles	role	NNS
cord-306424-gf0bglm0	298	4	of	of	IN
cord-306424-gf0bglm0	298	5	ATG	ATG	NNP
cord-306424-gf0bglm0	298	6	proteins	protein	NNS
cord-306424-gf0bglm0	298	7	Ubiquitin	Ubiquitin	NNP
cord-306424-gf0bglm0	298	8	and	and	CC
cord-306424-gf0bglm0	298	9	ubiquitin	ubiquitin	NN
cord-306424-gf0bglm0	298	10	-	-	HYPH
cord-306424-gf0bglm0	298	11	like	like	JJ
cord-306424-gf0bglm0	298	12	proteins	protein	NNS
cord-306424-gf0bglm0	298	13	as	as	IN
cord-306424-gf0bglm0	298	14	multifunctional	multifunctional	JJ
cord-306424-gf0bglm0	298	15	signals	signal	NNS
cord-306424-gf0bglm0	298	16	Ubiquitin	Ubiquitin	NNP
cord-306424-gf0bglm0	298	17	systems	system	NNS
cord-306424-gf0bglm0	298	18	mark	mark	VBP
cord-306424-gf0bglm0	298	19	pathogen	pathogen	NN
cord-306424-gf0bglm0	298	20	-	-	HYPH
cord-306424-gf0bglm0	298	21	containing	contain	VBG
cord-306424-gf0bglm0	298	22	vacuoles	vacuole	NNS
cord-306424-gf0bglm0	298	23	as	as	IN
cord-306424-gf0bglm0	298	24	targets	target	NNS
cord-306424-gf0bglm0	298	25	for	for	IN
cord-306424-gf0bglm0	298	26	host	host	NN
cord-306424-gf0bglm0	298	27	defense	defense	NN
cord-306424-gf0bglm0	298	28	by	by	IN
cord-306424-gf0bglm0	298	29	guanylate	guanylate	NN
cord-306424-gf0bglm0	298	30	binding	bind	VBG
cord-306424-gf0bglm0	298	31	proteins	protein	NNS
cord-306424-gf0bglm0	299	1	Virulent	virulent	JJ
cord-306424-gf0bglm0	299	2	toxoplasma	toxoplasma	NN
cord-306424-gf0bglm0	299	3	gondii	gondii	NN
cord-306424-gf0bglm0	299	4	evade	evade	VBP
cord-306424-gf0bglm0	299	5	immunity	immunity	NN
cord-306424-gf0bglm0	299	6	-	-	HYPH
cord-306424-gf0bglm0	299	7	related	relate	VBN
cord-306424-gf0bglm0	299	8	GTPase	GTPase	NNP
cord-306424-gf0bglm0	299	9	(	(	-LRB-
cord-306424-gf0bglm0	299	10	IRG)-Mediated	IRG)-Mediated	NNP
cord-306424-gf0bglm0	299	11	parasite	parasite	NN
cord-306424-gf0bglm0	299	12	vacuole	vacuole	NN
cord-306424-gf0bglm0	299	13	disruption	disruption	NN
cord-306424-gf0bglm0	299	14	within	within	IN
cord-306424-gf0bglm0	299	15	primed	prime	VBN
cord-306424-gf0bglm0	299	16	macrophages	macrophage	NNS
cord-306424-gf0bglm0	299	17	Coordinated	coordinated	JJ
cord-306424-gf0bglm0	299	18	loading	loading	NN
cord-306424-gf0bglm0	299	19	of	of	IN
cord-306424-gf0bglm0	299	20	IRG	IRG	NNP
cord-306424-gf0bglm0	299	21	resistance	resistance	NN
cord-306424-gf0bglm0	299	22	GTPases	gtpase	NNS
cord-306424-gf0bglm0	299	23	on	on	RP
cord-306424-gf0bglm0	299	24	to	to	IN
cord-306424-gf0bglm0	299	25	the	the	DT
cord-306424-gf0bglm0	299	26	Toxoplasma	Toxoplasma	NNP
cord-306424-gf0bglm0	299	27	gondii	gondii	NNP
cord-306424-gf0bglm0	299	28	parasitophorous	parasitophorous	JJ
cord-306424-gf0bglm0	299	29	vacuole	vacuole	NN
cord-306424-gf0bglm0	300	1	An	an	DT
cord-306424-gf0bglm0	300	2	autophagy	autophagy	NN
cord-306424-gf0bglm0	300	3	-	-	HYPH
cord-306424-gf0bglm0	300	4	independent	independent	JJ
cord-306424-gf0bglm0	300	5	role	role	NN
cord-306424-gf0bglm0	300	6	for	for	IN
cord-306424-gf0bglm0	300	7	LC3	lc3	NN
cord-306424-gf0bglm0	300	8	in	in	IN
cord-306424-gf0bglm0	301	1	equine	equine	JJ
cord-306424-gf0bglm0	301	2	arteritis	arteritis	NN
cord-306424-gf0bglm0	301	3	virus	virus	NN
cord-306424-gf0bglm0	301	4	replication	replication	NN
cord-306424-gf0bglm0	301	5	Coronaviruses	Coronaviruses	NNP
cord-306424-gf0bglm0	301	6	hijack	hijack	VBP
cord-306424-gf0bglm0	301	7	the	the	DT
cord-306424-gf0bglm0	301	8	LC3-Ipositive	LC3-Ipositive	NNP
cord-306424-gf0bglm0	301	9	EDEMosomes	edemosome	NNS
cord-306424-gf0bglm0	301	10	,	,	,
cord-306424-gf0bglm0	301	11	ER	ER	NNP
cord-306424-gf0bglm0	301	12	-	-	HYPH
cord-306424-gf0bglm0	301	13	derived	derive	VBN
cord-306424-gf0bglm0	301	14	vesicles	vesicle	NNS
cord-306424-gf0bglm0	301	15	exporting	export	VBG
cord-306424-gf0bglm0	301	16	short	short	RB
cord-306424-gf0bglm0	301	17	-	-	HYPH
cord-306424-gf0bglm0	301	18	lived	live	VBN
cord-306424-gf0bglm0	301	19	ERAD	ERAD	NNP
cord-306424-gf0bglm0	301	20	regulators	regulator	NNS
cord-306424-gf0bglm0	301	21	,	,	,
cord-306424-gf0bglm0	301	22	for	for	IN
cord-306424-gf0bglm0	301	23	replication	replication	NN
cord-306424-gf0bglm0	301	24	Nondegradative	Nondegradative	NNP
cord-306424-gf0bglm0	301	25	role	role	NN
cord-306424-gf0bglm0	301	26	of	of	IN
cord-306424-gf0bglm0	301	27	Atg5-Atg12	Atg5-Atg12	NNP
cord-306424-gf0bglm0	301	28	/	/	SYM
cord-306424-gf0bglm0	301	29	Atg16L1	Atg16L1	NNP
cord-306424-gf0bglm0	301	30	autophagy	autophagy	NN
cord-306424-gf0bglm0	301	31	protein	protein	NN
cord-306424-gf0bglm0	301	32	complex	complex	NN
cord-306424-gf0bglm0	301	33	in	in	IN
cord-306424-gf0bglm0	301	34	antiviral	antiviral	JJ
cord-306424-gf0bglm0	301	35	activity	activity	NN
cord-306424-gf0bglm0	301	36	of	of	IN
cord-306424-gf0bglm0	301	37	interferon	interferon	NN
cord-306424-gf0bglm0	301	38	gamma	gamma	NN
cord-306424-gf0bglm0	302	1	The	the	DT
cord-306424-gf0bglm0	302	2	Atg16L	Atg16L	NNP
cord-306424-gf0bglm0	302	3	complex	complex	NN
cord-306424-gf0bglm0	302	4	specifies	specify	VBZ
cord-306424-gf0bglm0	302	5	the	the	DT
cord-306424-gf0bglm0	302	6	site	site	NN
cord-306424-gf0bglm0	302	7	of	of	IN
cord-306424-gf0bglm0	302	8	LC3	LC3	NNP
cord-306424-gf0bglm0	302	9	lipidation	lipidation	NN
cord-306424-gf0bglm0	302	10	for	for	IN
cord-306424-gf0bglm0	302	11	membrane	membrane	NN
cord-306424-gf0bglm0	302	12	biogenesis	biogenesis	NN
cord-306424-gf0bglm0	302	13	in	in	IN
cord-306424-gf0bglm0	302	14	autophagy	autophagy	NN
cord-306424-gf0bglm0	303	1	GATE16	gate16	PRP
cord-306424-gf0bglm0	303	2	localize	localize	VB
cord-306424-gf0bglm0	303	3	to	to	IN
cord-306424-gf0bglm0	303	4	autophagosomal	autophagosomal	NN
cord-306424-gf0bglm0	303	5	membrane	membrane	NN
cord-306424-gf0bglm0	303	6	depending	depend	VBG
cord-306424-gf0bglm0	303	7	on	on	IN
cord-306424-gf0bglm0	303	8	form	form	NN
cord-306424-gf0bglm0	303	9	-	-	HYPH
cord-306424-gf0bglm0	303	10	II	ii	NN
cord-306424-gf0bglm0	303	11	formation	formation	NN
cord-306424-gf0bglm0	303	12	Human	human	JJ
cord-306424-gf0bglm0	303	13	light	light	NN
cord-306424-gf0bglm0	303	14	chain	chain	NN
cord-306424-gf0bglm0	303	15	3	3	CD
cord-306424-gf0bglm0	303	16	/	/	SYM
cord-306424-gf0bglm0	303	17	MAP1LC3	MAP1LC3	NNP
cord-306424-gf0bglm0	303	18	B	B	NNP
cord-306424-gf0bglm0	303	19	Is	be	VBZ
cord-306424-gf0bglm0	303	20	cleaved	cleave	VBN
cord-306424-gf0bglm0	303	21	at	at	IN
cord-306424-gf0bglm0	303	22	its	-PRON-	PRP$
cord-306424-gf0bglm0	303	23	carboxyl	carboxyl	NN
cord-306424-gf0bglm0	303	24	-	-	HYPH
cord-306424-gf0bglm0	303	25	terminal	terminal	NN
cord-306424-gf0bglm0	304	1	Met	meet	VBD
cord-306424-gf0bglm0	304	2	121	121	CD
cord-306424-gf0bglm0	304	3	to	to	TO
cord-306424-gf0bglm0	304	4	expose	expose	VB
cord-306424-gf0bglm0	304	5	Gly120	gly120	CD
cord-306424-gf0bglm0	304	6	for	for	IN
cord-306424-gf0bglm0	304	7	lipidation	lipidation	NN
cord-306424-gf0bglm0	304	8	and	and	CC
cord-306424-gf0bglm0	304	9	targeting	target	VBG
cord-306424-gf0bglm0	304	10	to	to	IN
cord-306424-gf0bglm0	304	11	autophagosomal	autophagosomal	NNP
cord-306424-gf0bglm0	304	12	membranes	membrane	NNS
cord-306424-gf0bglm0	305	1	HsAtg4B	HsAtg4B	NNP
cord-306424-gf0bglm0	305	2	/	/	SYM
cord-306424-gf0bglm0	305	3	HsApg4B	HsApg4B	NNP
cord-306424-gf0bglm0	305	4	/	/	SYM
cord-306424-gf0bglm0	305	5	autophagin-1	autophagin-1	NNP
cord-306424-gf0bglm0	305	6	cleaves	cleave	VBZ
cord-306424-gf0bglm0	305	7	the	the	DT
cord-306424-gf0bglm0	305	8	carboxyl	carboxyl	NN
cord-306424-gf0bglm0	305	9	termini	termini	NN
cord-306424-gf0bglm0	305	10	of	of	IN
cord-306424-gf0bglm0	305	11	three	three	CD
cord-306424-gf0bglm0	305	12	human	human	NN
cord-306424-gf0bglm0	305	13	Atg8	Atg8	NNP
cord-306424-gf0bglm0	305	14	homologues	homologue	NNS
cord-306424-gf0bglm0	305	15	and	and	CC
cord-306424-gf0bglm0	305	16	delipidates	delipidates	NNP
cord-306424-gf0bglm0	305	17	microtubule	microtubule	NN
cord-306424-gf0bglm0	305	18	-	-	HYPH
cord-306424-gf0bglm0	305	19	associated	associate	VBN
cord-306424-gf0bglm0	305	20	protein	protein	NN
cord-306424-gf0bglm0	305	21	light	light	NN
cord-306424-gf0bglm0	305	22	chain	chain	NN
cord-306424-gf0bglm0	306	1	3-and	3-and	NNP
cord-306424-gf0bglm0	306	2	GABAA	GABAA	NNP
cord-306424-gf0bglm0	306	3	receptor	receptor	NN
cord-306424-gf0bglm0	306	4	-	-	HYPH
cord-306424-gf0bglm0	306	5	associated	associate	VBN
cord-306424-gf0bglm0	306	6	protein	protein	NN
cord-306424-gf0bglm0	306	7	-	-	HYPH
cord-306424-gf0bglm0	306	8	phospholipid	phospholipid	NN
cord-306424-gf0bglm0	306	9	conjugates	conjugate	NNS
cord-306424-gf0bglm0	307	1	Autophagy	Autophagy	NNP
cord-306424-gf0bglm0	307	2	proteins	protein	NNS
cord-306424-gf0bglm0	307	3	regulate	regulate	VBP
cord-306424-gf0bglm0	307	4	ERK	ERK	NNP
cord-306424-gf0bglm0	307	5	phosphorylation	phosphorylation	NN
cord-306424-gf0bglm0	307	6	Autophagin-1	Autophagin-1	NNP
cord-306424-gf0bglm0	307	7	)	)	-RRB-
cord-306424-gf0bglm0	308	1	phosphorylation	phosphorylation	NN
cord-306424-gf0bglm0	308	2	modulates	modulate	VBZ
cord-306424-gf0bglm0	308	3	autophagy	autophagy	NN
cord-306424-gf0bglm0	309	1	Evolutionary	evolutionary	JJ
cord-306424-gf0bglm0	309	2	analyses	analysis	NNS
cord-306424-gf0bglm0	309	3	suggest	suggest	VBP
cord-306424-gf0bglm0	309	4	a	a	DT
cord-306424-gf0bglm0	309	5	function	function	NN
cord-306424-gf0bglm0	309	6	of	of	IN
cord-306424-gf0bglm0	309	7	MxB	mxb	JJ
cord-306424-gf0bglm0	309	8	immunity	immunity	NN
cord-306424-gf0bglm0	309	9	proteins	protein	NNS
cord-306424-gf0bglm0	309	10	beyond	beyond	IN
cord-306424-gf0bglm0	309	11	lentivirus	lentivirus	NN
cord-306424-gf0bglm0	309	12	restriction	restriction	NN
cord-306424-gf0bglm0	309	13	MX2	MX2	NNP
cord-306424-gf0bglm0	309	14	is	be	VBZ
cord-306424-gf0bglm0	309	15	an	an	DT
cord-306424-gf0bglm0	309	16	interferon	interferon	NN
cord-306424-gf0bglm0	309	17	-	-	HYPH
cord-306424-gf0bglm0	309	18	induced	induce	VBN
cord-306424-gf0bglm0	309	19	inhibitor	inhibitor	NN
cord-306424-gf0bglm0	309	20	of	of	IN
cord-306424-gf0bglm0	309	21	HIV-1	HIV-1	NNP
cord-306424-gf0bglm0	309	22	infection	infection	NN
cord-306424-gf0bglm0	309	23	Human	Human	NNP
cord-306424-gf0bglm0	309	24	MX2	MX2	NNP
cord-306424-gf0bglm0	309	25	is	be	VBZ
cord-306424-gf0bglm0	309	26	an	an	DT
cord-306424-gf0bglm0	309	27	interferon	interferon	NN
cord-306424-gf0bglm0	309	28	-	-	HYPH
cord-306424-gf0bglm0	309	29	induced	induce	VBN
cord-306424-gf0bglm0	309	30	postentry	postentry	NN
cord-306424-gf0bglm0	309	31	inhibitor	inhibitor	NN
cord-306424-gf0bglm0	309	32	of	of	IN
cord-306424-gf0bglm0	309	33	HIV-1	HIV-1	NNP
cord-306424-gf0bglm0	309	34	infection	infection	NN
cord-306424-gf0bglm0	310	1	The	the	DT
cord-306424-gf0bglm0	310	2	interferon	interferon	NN
cord-306424-gf0bglm0	310	3	-	-	HYPH
cord-306424-gf0bglm0	310	4	inducible	inducible	JJ
cord-306424-gf0bglm0	310	5	MxB	mxb	JJ
cord-306424-gf0bglm0	310	6	protein	protein	NN
cord-306424-gf0bglm0	310	7	inhibits	inhibit	VBZ
cord-306424-gf0bglm0	311	1	HIV-1	HIV-1	NNP
cord-306424-gf0bglm0	311	2	infection	infection	NN
cord-306424-gf0bglm0	311	3	Parallels	Parallels	NNPS
cord-306424-gf0bglm0	311	4	among	among	IN
cord-306424-gf0bglm0	311	5	positive	positive	JJ
cord-306424-gf0bglm0	311	6	-	-	HYPH
cord-306424-gf0bglm0	311	7	strand	strand	NN
cord-306424-gf0bglm0	311	8	RNA	RNA	NNP
cord-306424-gf0bglm0	311	9	viruses	virus	NNS
cord-306424-gf0bglm0	311	10	,	,	,
cord-306424-gf0bglm0	311	11	reversetranscribing	reversetranscribe	VBG
cord-306424-gf0bglm0	311	12	viruses	virus	NNS
cord-306424-gf0bglm0	311	13	and	and	CC
cord-306424-gf0bglm0	311	14	double	double	RB
cord-306424-gf0bglm0	311	15	-	-	HYPH
cord-306424-gf0bglm0	311	16	stranded	strand	VBN
cord-306424-gf0bglm0	311	17	RNA	RNA	NNP
cord-306424-gf0bglm0	311	18	viruses	virus	NNS
cord-306424-gf0bglm0	311	19	Enzo	Enzo	NNP
cord-306424-gf0bglm0	311	20	Scutigliani	Scutigliani	NNP
cord-306424-gf0bglm0	311	21	(	(	-LRB-
cord-306424-gf0bglm0	311	22	1993	1993	CD
cord-306424-gf0bglm0	311	23	)	)	-RRB-
cord-306424-gf0bglm0	311	24	obtained	obtain	VBD
cord-306424-gf0bglm0	311	25	a	a	DT
cord-306424-gf0bglm0	311	26	BSc	bsc	NN
cord-306424-gf0bglm0	311	27	in	in	IN
cord-306424-gf0bglm0	311	28	Biomedical	Biomedical	NNP
cord-306424-gf0bglm0	311	29	Sciences	Sciences	NNPS
cord-306424-gf0bglm0	311	30	with	with	IN
cord-306424-gf0bglm0	311	31	honor	honor	NN
cord-306424-gf0bglm0	311	32	at	at	IN
cord-306424-gf0bglm0	311	33	the	the	DT
cord-306424-gf0bglm0	311	34	University	University	NNP
cord-306424-gf0bglm0	311	35	of	of	IN
cord-306424-gf0bglm0	311	36	Amsterdam	Amsterdam	NNP
cord-306424-gf0bglm0	311	37	(	(	-LRB-
cord-306424-gf0bglm0	311	38	The	the	DT
cord-306424-gf0bglm0	311	39	Netherlands	Netherlands	NNP
cord-306424-gf0bglm0	311	40	)	)	-RRB-
cord-306424-gf0bglm0	311	41	in	in	IN
cord-306424-gf0bglm0	311	42	2014	2014	CD
cord-306424-gf0bglm0	311	43	,	,	,
cord-306424-gf0bglm0	311	44	and	and	CC
cord-306424-gf0bglm0	311	45	is	be	VBZ
cord-306424-gf0bglm0	311	46	currently	currently	RB
cord-306424-gf0bglm0	311	47	in	in	IN
cord-306424-gf0bglm0	311	48	the	the	DT
cord-306424-gf0bglm0	311	49	final	final	JJ
cord-306424-gf0bglm0	311	50	process	process	NN
cord-306424-gf0bglm0	311	51	of	of	IN
cord-306424-gf0bglm0	311	52	becoming	become	VBG
cord-306424-gf0bglm0	311	53	a	a	DT
cord-306424-gf0bglm0	311	54	MSc	msc	NN
cord-306424-gf0bglm0	311	55	with	with	IN
cord-306424-gf0bglm0	311	56	a	a	DT
cord-306424-gf0bglm0	311	57	specialization	specialization	NN
cord-306424-gf0bglm0	311	58	in	in	IN
cord-306424-gf0bglm0	311	59	cell	cell	NN
cord-306424-gf0bglm0	311	60	biology	biology	NN
cord-306424-gf0bglm0	311	61	and	and	CC
cord-306424-gf0bglm0	311	62	advanced	advanced	JJ
cord-306424-gf0bglm0	311	63	microscopy	microscopy	NNS
cord-306424-gf0bglm0	311	64	.	.	.
cord-306424-gf0bglm0	312	1	Over	over	IN
cord-306424-gf0bglm0	312	2	the	the	DT
cord-306424-gf0bglm0	312	3	last	last	JJ
cord-306424-gf0bglm0	312	4	years	year	NNS
cord-306424-gf0bglm0	312	5	,	,	,
cord-306424-gf0bglm0	312	6	he	-PRON-	PRP
cord-306424-gf0bglm0	312	7	developed	develop	VBD
cord-306424-gf0bglm0	312	8	a	a	DT
cord-306424-gf0bglm0	312	9	particular	particular	JJ
cord-306424-gf0bglm0	312	10	interest	interest	NN
cord-306424-gf0bglm0	312	11	for	for	IN
cord-306424-gf0bglm0	312	12	microbiology	microbiology	NN
cord-306424-gf0bglm0	312	13	,	,	,
cord-306424-gf0bglm0	312	14	and	and	CC
cord-306424-gf0bglm0	312	15	his	-PRON-	PRP$
cord-306424-gf0bglm0	312	16	ambition	ambition	NN
cord-306424-gf0bglm0	312	17	is	be	VBZ
cord-306424-gf0bglm0	312	18	to	to	TO
cord-306424-gf0bglm0	312	19	develop	develop	VB
cord-306424-gf0bglm0	312	20	novel	novel	JJ
cord-306424-gf0bglm0	312	21	treatment	treatment	NN
cord-306424-gf0bglm0	312	22	or	or	CC
cord-306424-gf0bglm0	312	23	vaccination	vaccination	NN
cord-306424-gf0bglm0	312	24	methods	method	NNS
cord-306424-gf0bglm0	312	25	by	by	IN
cord-306424-gf0bglm0	312	26	understanding	understand	VBG
cord-306424-gf0bglm0	312	27	pathogens	pathogen	NNS
cord-306424-gf0bglm0	312	28	at	at	IN
cord-306424-gf0bglm0	312	29	the	the	DT
cord-306424-gf0bglm0	312	30	molecular	molecular	JJ
cord-306424-gf0bglm0	312	31	level	level	NN
cord-306424-gf0bglm0	312	32	.	.	.
cord-306424-gf0bglm0	313	1	To	to	TO
cord-306424-gf0bglm0	313	2	achieve	achieve	VB
cord-306424-gf0bglm0	313	3	this	this	DT
cord-306424-gf0bglm0	313	4	goal	goal	NN
cord-306424-gf0bglm0	313	5	,	,	,
cord-306424-gf0bglm0	313	6	he	-PRON-	PRP
cord-306424-gf0bglm0	313	7	is	be	VBZ
cord-306424-gf0bglm0	313	8	currently	currently	RB
cord-306424-gf0bglm0	313	9	specializing	specialize	VBG
cord-306424-gf0bglm0	313	10	in	in	IN
cord-306424-gf0bglm0	313	11	combining	combine	VBG
cord-306424-gf0bglm0	313	12	microbiological	microbiological	JJ
cord-306424-gf0bglm0	313	13	research	research	NN
cord-306424-gf0bglm0	313	14	and	and	CC
cord-306424-gf0bglm0	313	15	advanced	advanced	JJ
cord-306424-gf0bglm0	313	16	microscopy	microscopy	NNS
cord-306424-gf0bglm0	313	17	.	.	.
cord-306424-gf0bglm0	314	1	A	a	DT
cord-306424-gf0bglm0	314	2	Molecular	Molecular	NNP
cord-306424-gf0bglm0	314	3	Sciences	Sciences	NNPS
cord-306424-gf0bglm0	314	4	study	study	NN
cord-306424-gf0bglm0	314	5	at	at	IN
cord-306424-gf0bglm0	314	6	Wageningen	Wageningen	NNP
cord-306424-gf0bglm0	314	7	University	University	NNP
cord-306424-gf0bglm0	314	8	and	and	CC
cord-306424-gf0bglm0	314	9	Research	Research	NNP
cord-306424-gf0bglm0	314	10	Center	Center	NNP
cord-306424-gf0bglm0	314	11	(	(	-LRB-
cord-306424-gf0bglm0	314	12	The	the	DT
cord-306424-gf0bglm0	314	13	Netherlands	Netherlands	NNP
cord-306424-gf0bglm0	314	14	)	)	-RRB-
cord-306424-gf0bglm0	314	15	motivated	motivate	VBD
cord-306424-gf0bglm0	314	16	Marjolein	Marjolein	NNP
cord-306424-gf0bglm0	314	17	Kikkert	Kikkert	NNP
cord-306424-gf0bglm0	314	18	(	(	-LRB-
cord-306424-gf0bglm0	314	19	1969	1969	CD
cord-306424-gf0bglm0	314	20	)	)	-RRB-
cord-306424-gf0bglm0	314	21	to	to	TO
cord-306424-gf0bglm0	314	22	pursue	pursue	VB
cord-306424-gf0bglm0	314	23	a	a	DT
cord-306424-gf0bglm0	314	24	Ph.D.	ph.d.	NN
cord-306424-gf0bglm0	314	25	degree	degree	NN
cord-306424-gf0bglm0	314	26	,	,	,
cord-306424-gf0bglm0	314	27	which	which	WDT
cord-306424-gf0bglm0	314	28	she	-PRON-	PRP
cord-306424-gf0bglm0	314	29	achieved	achieve	VBD
cord-306424-gf0bglm0	314	30	in	in	IN
cord-306424-gf0bglm0	314	31	1999	1999	CD
cord-306424-gf0bglm0	314	32	at	at	IN
cord-306424-gf0bglm0	314	33	the	the	DT
cord-306424-gf0bglm0	314	34	Department	Department	NNP
cord-306424-gf0bglm0	314	35	of	of	IN
cord-306424-gf0bglm0	314	36	Virology	Virology	NNP
cord-306424-gf0bglm0	314	37	of	of	IN
cord-306424-gf0bglm0	314	38	this	this	DT
cord-306424-gf0bglm0	314	39	University	University	NNP
cord-306424-gf0bglm0	314	40	.	.	.
cord-306424-gf0bglm0	315	1	Her	-PRON-	PRP$
cord-306424-gf0bglm0	315	2	thesis	thesis	NN
cord-306424-gf0bglm0	315	3	was	be	VBD
cord-306424-gf0bglm0	315	4	entitled	entitle	VBN
cord-306424-gf0bglm0	315	5	"	"	``
cord-306424-gf0bglm0	315	6	Role	role	NN
cord-306424-gf0bglm0	315	7	of	of	IN
cord-306424-gf0bglm0	315	8	the	the	DT
cord-306424-gf0bglm0	315	9	envelope	envelope	NN
cord-306424-gf0bglm0	315	10	glycoproteins	glycoprotein	NNS
cord-306424-gf0bglm0	315	11	in	in	IN
cord-306424-gf0bglm0	315	12	the	the	DT
cord-306424-gf0bglm0	315	13	infection	infection	NN
cord-306424-gf0bglm0	315	14	of	of	IN
cord-306424-gf0bglm0	315	15	tomato	tomato	NN
cord-306424-gf0bglm0	315	16	spotted	spot	VBN
cord-306424-gf0bglm0	315	17	wilt	wilt	NN
cord-306424-gf0bglm0	315	18	virus	virus	NN
cord-306424-gf0bglm0	315	19	"	"	''
cord-306424-gf0bglm0	315	20	.	.	.
cord-306424-gf0bglm0	316	1	She	-PRON-	PRP
cord-306424-gf0bglm0	316	2	then	then	RB
cord-306424-gf0bglm0	316	3	switched	switch	VBD
cord-306424-gf0bglm0	316	4	to	to	IN
cord-306424-gf0bglm0	316	5	mammalian	mammalian	JJ
cord-306424-gf0bglm0	316	6	Virology	Virology	NNP
cord-306424-gf0bglm0	316	7	,	,	,
cord-306424-gf0bglm0	316	8	became	become	VBD
cord-306424-gf0bglm0	316	9	a	a	DT
cord-306424-gf0bglm0	316	10	post	post	NN
cord-306424-gf0bglm0	316	11	-	-	JJ
cord-306424-gf0bglm0	316	12	doc	doc	NN
cord-306424-gf0bglm0	316	13	at	at	IN
cord-306424-gf0bglm0	316	14	the	the	DT
cord-306424-gf0bglm0	316	15	National	National	NNP
cord-306424-gf0bglm0	316	16	Institute	Institute	NNP
cord-306424-gf0bglm0	316	17	of	of	IN
cord-306424-gf0bglm0	316	18	Health	Health	NNP
cord-306424-gf0bglm0	316	19	and	and	CC
cord-306424-gf0bglm0	316	20	the	the	DT
cord-306424-gf0bglm0	316	21	Environment	Environment	NNP
cord-306424-gf0bglm0	316	22	in	in	IN
cord-306424-gf0bglm0	316	23	Bilthoven	Bilthoven	NNP
cord-306424-gf0bglm0	316	24	,	,	,
cord-306424-gf0bglm0	316	25	the	the	DT
cord-306424-gf0bglm0	316	26	Netherlands	Netherlands	NNP
cord-306424-gf0bglm0	316	27	with	with	IN
cord-306424-gf0bglm0	316	28	prof	prof	NNP
cord-306424-gf0bglm0	316	29	.	.	.
cord-306424-gf0bglm0	317	1	Emmanuel	Emmanuel	NNP
cord-306424-gf0bglm0	317	2	Wiertz	Wiertz	NNP
cord-306424-gf0bglm0	317	3	,	,	,
cord-306424-gf0bglm0	317	4	and	and	CC
cord-306424-gf0bglm0	317	5	subsequently	subsequently	RB
cord-306424-gf0bglm0	317	6	at	at	IN
cord-306424-gf0bglm0	317	7	Leiden	Leiden	NNP
cord-306424-gf0bglm0	317	8	University	University	NNP
cord-306424-gf0bglm0	317	9	Medical	Medical	NNP
cord-306424-gf0bglm0	317	10	Center	Center	NNP
cord-306424-gf0bglm0	317	11	(	(	-LRB-
cord-306424-gf0bglm0	317	12	LUMC	LUMC	NNP
cord-306424-gf0bglm0	317	13	)	)	-RRB-
cord-306424-gf0bglm0	317	14	,	,	,
cord-306424-gf0bglm0	317	15	working	work	VBG
cord-306424-gf0bglm0	317	16	on	on	IN
cord-306424-gf0bglm0	317	17	immune	immune	JJ
cord-306424-gf0bglm0	317	18	evasion	evasion	NN
cord-306424-gf0bglm0	317	19	strategies	strategy	NNS
cord-306424-gf0bglm0	317	20	of	of	IN
cord-306424-gf0bglm0	317	21	human	human	JJ
cord-306424-gf0bglm0	317	22	cytomegalovirus	cytomegalovirus	NN
cord-306424-gf0bglm0	317	23	.	.	.
cord-306424-gf0bglm0	318	1	After	after	IN
cord-306424-gf0bglm0	318	2	this	this	DT
cord-306424-gf0bglm0	318	3	she	-PRON-	PRP
cord-306424-gf0bglm0	318	4	started	start	VBD
cord-306424-gf0bglm0	318	5	working	work	VBG
cord-306424-gf0bglm0	318	6	with	with	IN
cord-306424-gf0bglm0	318	7	Prof.	Prof.	NNP
cord-306424-gf0bglm0	318	8	Eric	Eric	NNP
cord-306424-gf0bglm0	318	9	Snijder	Snijder	NNP
cord-306424-gf0bglm0	318	10	at	at	IN
cord-306424-gf0bglm0	318	11	the	the	DT
cord-306424-gf0bglm0	318	12	LUMC	LUMC	NNP
cord-306424-gf0bglm0	318	13	as	as	IN
cord-306424-gf0bglm0	318	14	a	a	DT
cord-306424-gf0bglm0	318	15	post	post	NN
cord-306424-gf0bglm0	318	16	-	-	JJ
cord-306424-gf0bglm0	318	17	doc	doc	NN
cord-306424-gf0bglm0	318	18	,	,	,
cord-306424-gf0bglm0	318	19	and	and	CC
cord-306424-gf0bglm0	318	20	developed	develop	VBD
cord-306424-gf0bglm0	318	21	into	into	IN
cord-306424-gf0bglm0	318	22	an	an	DT
cord-306424-gf0bglm0	318	23	Assistant	Assistant	NNP
cord-306424-gf0bglm0	318	24	Professor	Professor	NNP
cord-306424-gf0bglm0	318	25	in	in	IN
cord-306424-gf0bglm0	318	26	the	the	DT
cord-306424-gf0bglm0	318	27	Department	Department	NNP
cord-306424-gf0bglm0	318	28	of	of	IN
cord-306424-gf0bglm0	318	29	Medical	Medical	NNP
cord-306424-gf0bglm0	318	30	Microbiology	Microbiology	NNP
cord-306424-gf0bglm0	318	31	.	.	.
cord-306424-gf0bglm0	319	1	Her	-PRON-	PRP$
cord-306424-gf0bglm0	319	2	research	research	NN
cord-306424-gf0bglm0	319	3	currently	currently	RB
cord-306424-gf0bglm0	319	4	focuses	focus	VBZ
cord-306424-gf0bglm0	319	5	on	on	IN
cord-306424-gf0bglm0	319	6	the	the	DT
cord-306424-gf0bglm0	319	7	replication	replication	NN
cord-306424-gf0bglm0	319	8	organelles	organelle	NNS
cord-306424-gf0bglm0	319	9	and	and	CC
cord-306424-gf0bglm0	319	10	related	related	JJ
cord-306424-gf0bglm0	319	11	virus	virus	NN
cord-306424-gf0bglm0	319	12	-	-	HYPH
cord-306424-gf0bglm0	319	13	host	host	NN
cord-306424-gf0bglm0	319	14	interactions	interaction	NNS
cord-306424-gf0bglm0	319	15	of	of	IN
cord-306424-gf0bglm0	319	16	nidoviruses	nidoviruse	NNS
cord-306424-gf0bglm0	319	17	and	and	CC
cord-306424-gf0bglm0	320	1	other	other	JJ
cord-306424-gf0bglm0	320	2	+	+	CC
cord-306424-gf0bglm0	320	3	RNA	RNA	NNP
cord-306424-gf0bglm0	320	4	viruses	virus	NNS
cord-306424-gf0bglm0	320	5	,	,	,
cord-306424-gf0bglm0	320	6	and	and	CC
cord-306424-gf0bglm0	320	7	the	the	DT
cord-306424-gf0bglm0	320	8	innate	innate	JJ
cord-306424-gf0bglm0	320	9	immune	immune	JJ
cord-306424-gf0bglm0	320	10	evasion	evasion	NN
cord-306424-gf0bglm0	320	11	mechanisms	mechanism	NNS
cord-306424-gf0bglm0	320	12	which	which	WDT
cord-306424-gf0bglm0	320	13	these	these	DT
cord-306424-gf0bglm0	320	14	viruses	virus	NNS
cord-306424-gf0bglm0	320	15	employ	employ	VBP
cord-306424-gf0bglm0	320	16	.	.	.
cord-306424-gf0bglm0	321	1	The	the	DT
cord-306424-gf0bglm0	321	2	knowledge	knowledge	NN
cord-306424-gf0bglm0	321	3	gained	gain	VBD
cord-306424-gf0bglm0	321	4	from	from	IN
cord-306424-gf0bglm0	321	5	her	-PRON-	PRP$
cord-306424-gf0bglm0	321	6	research	research	NN
cord-306424-gf0bglm0	321	7	is	be	VBZ
cord-306424-gf0bglm0	321	8	being	be	VBG
cord-306424-gf0bglm0	321	9	used	use	VBN
cord-306424-gf0bglm0	321	10	for	for	IN
cord-306424-gf0bglm0	321	11	development	development	NN
cord-306424-gf0bglm0	321	12	of	of	IN
cord-306424-gf0bglm0	321	13	novel	novel	JJ
cord-306424-gf0bglm0	321	14	antiviral	antiviral	JJ
cord-306424-gf0bglm0	321	15	vaccines	vaccine	NNS
cord-306424-gf0bglm0	321	16	and	and	CC
cord-306424-gf0bglm0	321	17	Àdrugs	Àdrugs	NNP
cord-306424-gf0bglm0	321	18	.	.	.