id author title date pages extension mime words sentences flesch summary cache txt cord-007255-jmjolo9p Pulliam, Juliet R. C. Ability to replicate in the cytoplasm predicts zoonotic transmission of livestock viruses 2009-02-15 .txt text/plain 2458 117 42 The database contains information on the 3 molecular characteristics hypothesized to influence the potential of a virus to cross host species: site of replication (X SR ; whether replication is completed in the cytoplasm or requires nuclear entry), genomic material (X GM ; RNA or DNA), and segmentation of the viral genome (X Seg ; segmented or nonsegmented). Hypothesis testing allowed us to determine how likely it was that the observed patterns were due to chance, whereas model-based prediction allowed us to determine what trait or set of traits was the best predictor of a livestock virus's ability to infect humans and to estimate the probability that a particular virus species would be able to jump host species, given knowledge of the traits of interest. To examine the magnitude and relative importance of the effects that the 3 molecular characteristics of interest have on the ability of the viral species in the database to infect humans, we developed a set of logistic regression models. ./cache/cord-007255-jmjolo9p.txt ./txt/cord-007255-jmjolo9p.txt