id	sid	tid	token	lemma	pos
cord-279260-tdvb0fhv	1	1	key	key	NN
cord-279260-tdvb0fhv	1	2	:	:	:
cord-279260-tdvb0fhv	2	1	cord-279260-tdvb0fhv	cord-279260-tdvb0fhv	LS
cord-279260-tdvb0fhv	2	2	authors	author	NNS
cord-279260-tdvb0fhv	2	3	:	:	:
cord-279260-tdvb0fhv	2	4	Lv	Lv	NNP
cord-279260-tdvb0fhv	2	5	,	,	,
cord-279260-tdvb0fhv	2	6	Huibin	Huibin	NNP
cord-279260-tdvb0fhv	2	7	;	;	:
cord-279260-tdvb0fhv	3	1	Wu	Wu	NNP
cord-279260-tdvb0fhv	3	2	,	,	,
cord-279260-tdvb0fhv	3	3	Nicholas	Nicholas	NNP
cord-279260-tdvb0fhv	3	4	C.	C.	NNP
cord-279260-tdvb0fhv	3	5	;	;	:
cord-279260-tdvb0fhv	3	6	Mok	Mok	NNP
cord-279260-tdvb0fhv	3	7	,	,	,
cord-279260-tdvb0fhv	3	8	Chris	Chris	NNP
cord-279260-tdvb0fhv	3	9	K.	K.	NNP
cord-279260-tdvb0fhv	3	10	P.	P.	NNP
cord-279260-tdvb0fhv	3	11	title	title	NN
cord-279260-tdvb0fhv	3	12	:	:	:
cord-279260-tdvb0fhv	3	13	COVID‐19	COVID‐19	NNP
cord-279260-tdvb0fhv	3	14	vaccines	vaccine	NNS
cord-279260-tdvb0fhv	3	15	:	:	:
cord-279260-tdvb0fhv	3	16	knowing	know	VBG
cord-279260-tdvb0fhv	3	17	the	the	DT
cord-279260-tdvb0fhv	3	18	unknown	unknown	JJ
cord-279260-tdvb0fhv	3	19	date	date	NN
cord-279260-tdvb0fhv	3	20	:	:	:
cord-279260-tdvb0fhv	3	21	2020	2020	CD
cord-279260-tdvb0fhv	3	22	-	-	HYPH
cord-279260-tdvb0fhv	3	23	05	05	CD
cord-279260-tdvb0fhv	3	24	-	-	SYM
cord-279260-tdvb0fhv	3	25	21	21	CD
cord-279260-tdvb0fhv	3	26	journal	journal	NN
cord-279260-tdvb0fhv	3	27	:	:	:
cord-279260-tdvb0fhv	4	1	Eur	Eur	NNP
cord-279260-tdvb0fhv	4	2	J	J	NNP
cord-279260-tdvb0fhv	4	3	Immunol	Immunol	NNP
cord-279260-tdvb0fhv	4	4	DOI	DOI	NNP
cord-279260-tdvb0fhv	4	5	:	:	:
cord-279260-tdvb0fhv	4	6	10.1002	10.1002	CD
cord-279260-tdvb0fhv	4	7	/	/	SYM
cord-279260-tdvb0fhv	4	8	eji.202048663	eji.202048663	NNP
cord-279260-tdvb0fhv	4	9	sha	sha	NNP
cord-279260-tdvb0fhv	4	10	:	:	:
cord-279260-tdvb0fhv	4	11	a72a57143cd50bb910eb222c50394cd1314b6f75	a72a57143cd50bb910eb222c50394cd1314b6f75	NNP
cord-279260-tdvb0fhv	4	12	doc_id	doc_id	CD
cord-279260-tdvb0fhv	4	13	:	:	:
cord-279260-tdvb0fhv	4	14	279260	279260	CD
cord-279260-tdvb0fhv	4	15	cord_uid	cord_uid	NNS
cord-279260-tdvb0fhv	4	16	:	:	:
cord-279260-tdvb0fhv	5	1	tdvb0fhv	tdvb0fhv	NNP
cord-279260-tdvb0fhv	5	2	Vaccine	Vaccine	NNP
cord-279260-tdvb0fhv	5	3	development	development	NN
cord-279260-tdvb0fhv	5	4	against	against	IN
cord-279260-tdvb0fhv	5	5	SARS‐CoV‐2	SARS‐CoV‐2	NNP
cord-279260-tdvb0fhv	5	6	has	have	VBZ
cord-279260-tdvb0fhv	5	7	drawn	draw	VBN
cord-279260-tdvb0fhv	5	8	attention	attention	NN
cord-279260-tdvb0fhv	5	9	around	around	IN
cord-279260-tdvb0fhv	5	10	the	the	DT
cord-279260-tdvb0fhv	5	11	globe	globe	NN
cord-279260-tdvb0fhv	5	12	due	due	JJ
cord-279260-tdvb0fhv	5	13	to	to	IN
cord-279260-tdvb0fhv	5	14	the	the	DT
cord-279260-tdvb0fhv	5	15	exploding	explode	VBG
cord-279260-tdvb0fhv	5	16	pandemic	pandemic	NN
cord-279260-tdvb0fhv	5	17	.	.	.
cord-279260-tdvb0fhv	6	1	Although	although	IN
cord-279260-tdvb0fhv	6	2	COVID‐19	COVID‐19	NNP
cord-279260-tdvb0fhv	6	3	is	be	VBZ
cord-279260-tdvb0fhv	6	4	caused	cause	VBN
cord-279260-tdvb0fhv	6	5	by	by	IN
cord-279260-tdvb0fhv	6	6	a	a	DT
cord-279260-tdvb0fhv	6	7	new	new	JJ
cord-279260-tdvb0fhv	6	8	coronavirus	coronavirus	NN
cord-279260-tdvb0fhv	6	9	,	,	,
cord-279260-tdvb0fhv	6	10	SARS‐CoV‐2	SARS‐CoV‐2	NNP
cord-279260-tdvb0fhv	6	11	,	,	,
cord-279260-tdvb0fhv	6	12	previous	previous	JJ
cord-279260-tdvb0fhv	6	13	research	research	NN
cord-279260-tdvb0fhv	6	14	on	on	IN
cord-279260-tdvb0fhv	6	15	other	other	JJ
cord-279260-tdvb0fhv	6	16	coronavirus	coronavirus	NN
cord-279260-tdvb0fhv	6	17	vaccines	vaccine	NNS
cord-279260-tdvb0fhv	6	18	,	,	,
cord-279260-tdvb0fhv	6	19	such	such	JJ
cord-279260-tdvb0fhv	6	20	as	as	IN
cord-279260-tdvb0fhv	6	21	FIPV	FIPV	NNP
cord-279260-tdvb0fhv	6	22	,	,	,
cord-279260-tdvb0fhv	6	23	SARS	SARS	NNP
cord-279260-tdvb0fhv	6	24	and	and	CC
cord-279260-tdvb0fhv	6	25	MERS	MERS	NNP
cord-279260-tdvb0fhv	6	26	,	,	,
cord-279260-tdvb0fhv	6	27	has	have	VBZ
cord-279260-tdvb0fhv	6	28	provided	provide	VBN
cord-279260-tdvb0fhv	6	29	valuable	valuable	JJ
cord-279260-tdvb0fhv	6	30	information	information	NN
cord-279260-tdvb0fhv	6	31	for	for	IN
cord-279260-tdvb0fhv	6	32	the	the	DT
cord-279260-tdvb0fhv	6	33	rapid	rapid	JJ
cord-279260-tdvb0fhv	6	34	development	development	NN
cord-279260-tdvb0fhv	6	35	of	of	IN
cord-279260-tdvb0fhv	6	36	COVID‐19	COVID‐19	NNP
cord-279260-tdvb0fhv	6	37	vaccine	vaccine	NN
cord-279260-tdvb0fhv	6	38	.	.	.
cord-279260-tdvb0fhv	7	1	However	however	RB
cord-279260-tdvb0fhv	7	2	,	,	,
cord-279260-tdvb0fhv	7	3	important	important	JJ
cord-279260-tdvb0fhv	7	4	knowledge	knowledge	NN
cord-279260-tdvb0fhv	7	5	gaps	gap	NNS
cord-279260-tdvb0fhv	7	6	remain	remain	VBP
cord-279260-tdvb0fhv	7	7	–	–	:
cord-279260-tdvb0fhv	7	8	some	some	DT
cord-279260-tdvb0fhv	7	9	are	be	VBP
cord-279260-tdvb0fhv	7	10	specific	specific	JJ
cord-279260-tdvb0fhv	7	11	to	to	IN
cord-279260-tdvb0fhv	7	12	SARS‐CoV‐2	SARS‐CoV‐2	NNP
cord-279260-tdvb0fhv	7	13	,	,	,
cord-279260-tdvb0fhv	7	14	others	other	NNS
cord-279260-tdvb0fhv	7	15	are	be	VBP
cord-279260-tdvb0fhv	7	16	fundamental	fundamental	JJ
cord-279260-tdvb0fhv	7	17	to	to	IN
cord-279260-tdvb0fhv	7	18	immunology	immunology	NN
cord-279260-tdvb0fhv	7	19	and	and	CC
cord-279260-tdvb0fhv	7	20	vaccinology	vaccinology	NN
cord-279260-tdvb0fhv	7	21	.	.	.
cord-279260-tdvb0fhv	8	1	Here	here	RB
cord-279260-tdvb0fhv	8	2	we	-PRON-	PRP
cord-279260-tdvb0fhv	8	3	discuss	discuss	VBP
cord-279260-tdvb0fhv	8	4	areas	area	NNS
cord-279260-tdvb0fhv	8	5	that	that	WDT
cord-279260-tdvb0fhv	8	6	need	need	VBP
cord-279260-tdvb0fhv	8	7	to	to	TO
cord-279260-tdvb0fhv	8	8	be	be	VB
cord-279260-tdvb0fhv	8	9	addressed	address	VBN
cord-279260-tdvb0fhv	8	10	for	for	IN
cord-279260-tdvb0fhv	8	11	COVID‐19	COVID‐19	NNP
cord-279260-tdvb0fhv	8	12	vaccine	vaccine	NN
cord-279260-tdvb0fhv	8	13	development	development	NN
cord-279260-tdvb0fhv	8	14	,	,	,
cord-279260-tdvb0fhv	8	15	and	and	CC
cord-279260-tdvb0fhv	8	16	what	what	WP
cord-279260-tdvb0fhv	8	17	can	can	MD
cord-279260-tdvb0fhv	8	18	be	be	VB
cord-279260-tdvb0fhv	8	19	learned	learn	VBN
cord-279260-tdvb0fhv	8	20	from	from	IN
cord-279260-tdvb0fhv	8	21	examples	example	NNS
cord-279260-tdvb0fhv	8	22	of	of	IN
cord-279260-tdvb0fhv	8	23	vaccine	vaccine	NN
cord-279260-tdvb0fhv	8	24	development	development	NN
cord-279260-tdvb0fhv	8	25	in	in	IN
cord-279260-tdvb0fhv	8	26	the	the	DT
cord-279260-tdvb0fhv	8	27	past	past	NN
cord-279260-tdvb0fhv	8	28	.	.	.
cord-279260-tdvb0fhv	9	1	Since	since	IN
cord-279260-tdvb0fhv	9	2	the	the	DT
cord-279260-tdvb0fhv	9	3	beginning	beginning	NN
cord-279260-tdvb0fhv	9	4	of	of	IN
cord-279260-tdvb0fhv	9	5	the	the	DT
cord-279260-tdvb0fhv	9	6	outbreak	outbreak	NN
cord-279260-tdvb0fhv	9	7	,	,	,
cord-279260-tdvb0fhv	9	8	the	the	DT
cord-279260-tdvb0fhv	9	9	research	research	NN
cord-279260-tdvb0fhv	9	10	progress	progress	NN
cord-279260-tdvb0fhv	9	11	on	on	IN
cord-279260-tdvb0fhv	9	12	COVID‐19	COVID‐19	NNP
cord-279260-tdvb0fhv	9	13	has	have	VBZ
cord-279260-tdvb0fhv	9	14	been	be	VBN
cord-279260-tdvb0fhv	9	15	remarkable	remarkable	JJ
cord-279260-tdvb0fhv	9	16	.	.	.
cord-279260-tdvb0fhv	10	1	We	-PRON-	PRP
cord-279260-tdvb0fhv	10	2	are	be	VBP
cord-279260-tdvb0fhv	10	3	therefore	therefore	RB
cord-279260-tdvb0fhv	10	4	optimistic	optimistic	JJ
cord-279260-tdvb0fhv	10	5	about	about	IN
cord-279260-tdvb0fhv	10	6	the	the	DT
cord-279260-tdvb0fhv	10	7	rapid	rapid	JJ
cord-279260-tdvb0fhv	10	8	development	development	NN
cord-279260-tdvb0fhv	10	9	of	of	IN
cord-279260-tdvb0fhv	10	10	COVID‐19	COVID‐19	NNP
cord-279260-tdvb0fhv	10	11	vaccine	vaccine	NN
cord-279260-tdvb0fhv	10	12	.	.	.
cord-279260-tdvb0fhv	11	1	This	this	DT
cord-279260-tdvb0fhv	11	2	article	article	NN
cord-279260-tdvb0fhv	11	3	is	be	VBZ
cord-279260-tdvb0fhv	11	4	protected	protect	VBN
cord-279260-tdvb0fhv	11	5	by	by	IN
cord-279260-tdvb0fhv	11	6	copyright	copyright	NN
cord-279260-tdvb0fhv	11	7	.	.	.
cord-279260-tdvb0fhv	12	1	All	all	DT
cord-279260-tdvb0fhv	12	2	rights	right	NNS
cord-279260-tdvb0fhv	12	3	reserved	reserve	VBN
cord-279260-tdvb0fhv	12	4	namely	namely	RB
cord-279260-tdvb0fhv	12	5	inactivated	inactivate	VBN
cord-279260-tdvb0fhv	12	6	virus	virus	NN
cord-279260-tdvb0fhv	12	7	,	,	,
cord-279260-tdvb0fhv	12	8	lipid	lipid	NN
cord-279260-tdvb0fhv	12	9	nanoparticle	nanoparticle	NN
cord-279260-tdvb0fhv	12	10	(	(	-LRB-
cord-279260-tdvb0fhv	12	11	LNP)-encapsulated	lnp)-encapsulate	VBN
cord-279260-tdvb0fhv	12	12	mRNA	mrna	NN
cord-279260-tdvb0fhv	12	13	,	,	,
cord-279260-tdvb0fhv	12	14	and	and	CC
cord-279260-tdvb0fhv	12	15	plasmid	plasmid	NN
cord-279260-tdvb0fhv	12	16	DNA	dna	NN
cord-279260-tdvb0fhv	12	17	,	,	,
cord-279260-tdvb0fhv	12	18	are	be	VBP
cord-279260-tdvb0fhv	12	19	in	in	IN
cord-279260-tdvb0fhv	12	20	phase	phase	NN
cord-279260-tdvb0fhv	13	1	I	-PRON-	PRP
cord-279260-tdvb0fhv	13	2	clinical	clinical	JJ
cord-279260-tdvb0fhv	13	3	trials	trial	NNS
cord-279260-tdvb0fhv	13	4	(	(	-LRB-
cord-279260-tdvb0fhv	13	5	https://www.who.int/blueprint/priority-diseases/key-action/novel-coronavirus-landscape-ncov.pdf	https://www.who.int/blueprint/priority-diseases/key-action/novel-coronavirus-landscape-ncov.pdf	NNP
cord-279260-tdvb0fhv	13	6	)	)	-RRB-
cord-279260-tdvb0fhv	13	7	.	.	.
cord-279260-tdvb0fhv	14	1	Other	other	JJ
cord-279260-tdvb0fhv	14	2	platforms	platform	NNS
cord-279260-tdvb0fhv	14	3	,	,	,
cord-279260-tdvb0fhv	14	4	such	such	JJ
cord-279260-tdvb0fhv	14	5	as	as	IN
cord-279260-tdvb0fhv	14	6	live	live	JJ
cord-279260-tdvb0fhv	14	7	attenuated	attenuated	JJ
cord-279260-tdvb0fhv	14	8	virus	virus	NN
cord-279260-tdvb0fhv	14	9	,	,	,
cord-279260-tdvb0fhv	14	10	protein	protein	NN
cord-279260-tdvb0fhv	14	11	subunit	subunit	NN
cord-279260-tdvb0fhv	14	12	,	,	,
cord-279260-tdvb0fhv	14	13	are	be	VBP
cord-279260-tdvb0fhv	14	14	also	also	RB
cord-279260-tdvb0fhv	14	15	being	be	VBG
cord-279260-tdvb0fhv	14	16	evaluated	evaluate	VBN
cord-279260-tdvb0fhv	14	17	at	at	IN
cord-279260-tdvb0fhv	14	18	the	the	DT
cord-279260-tdvb0fhv	14	19	pre	pre	JJ
cord-279260-tdvb0fhv	14	20	-	-	JJ
cord-279260-tdvb0fhv	14	21	clinical	clinical	JJ
cord-279260-tdvb0fhv	14	22	stage	stage	NN
cord-279260-tdvb0fhv	14	23	.	.	.
cord-279260-tdvb0fhv	15	1	Although	although	IN
cord-279260-tdvb0fhv	15	2	there	there	EX
cord-279260-tdvb0fhv	15	3	is	be	VBZ
cord-279260-tdvb0fhv	15	4	an	an	DT
cord-279260-tdvb0fhv	15	5	urgent	urgent	JJ
cord-279260-tdvb0fhv	15	6	need	need	NN
cord-279260-tdvb0fhv	15	7	for	for	IN
cord-279260-tdvb0fhv	15	8	these	these	DT
cord-279260-tdvb0fhv	15	9	vaccines	vaccine	NNS
cord-279260-tdvb0fhv	15	10	to	to	TO
cord-279260-tdvb0fhv	15	11	become	become	VB
cord-279260-tdvb0fhv	15	12	available	available	JJ
cord-279260-tdvb0fhv	15	13	,	,	,
cord-279260-tdvb0fhv	15	14	several	several	JJ
cord-279260-tdvb0fhv	15	15	critical	critical	JJ
cord-279260-tdvb0fhv	15	16	features	feature	NNS
cord-279260-tdvb0fhv	15	17	of	of	IN
cord-279260-tdvb0fhv	15	18	the	the	DT
cord-279260-tdvb0fhv	15	19	COVID-19	covid-19	JJ
cord-279260-tdvb0fhv	15	20	vaccine	vaccine	NN
cord-279260-tdvb0fhv	15	21	will	will	MD
cord-279260-tdvb0fhv	15	22	need	need	VB
cord-279260-tdvb0fhv	15	23	to	to	TO
cord-279260-tdvb0fhv	15	24	be	be	VB
cord-279260-tdvb0fhv	15	25	assessed	assess	VBN
cord-279260-tdvb0fhv	15	26	,	,	,
cord-279260-tdvb0fhv	15	27	based	base	VBN
cord-279260-tdvb0fhv	15	28	on	on	IN
cord-279260-tdvb0fhv	15	29	the	the	DT
cord-279260-tdvb0fhv	15	30	experience	experience	NN
cord-279260-tdvb0fhv	15	31	from	from	IN
cord-279260-tdvb0fhv	15	32	previous	previous	JJ
cord-279260-tdvb0fhv	15	33	vaccine	vaccine	NN
cord-279260-tdvb0fhv	15	34	development	development	NN
cord-279260-tdvb0fhv	15	35	for	for	IN
cord-279260-tdvb0fhv	15	36	Feline	Feline	NNP
cord-279260-tdvb0fhv	15	37	-	-	HYPH
cord-279260-tdvb0fhv	15	38	CoVs	CoVs	NNP
cord-279260-tdvb0fhv	15	39	,	,	,
cord-279260-tdvb0fhv	15	40	MERS	MERS	NNP
cord-279260-tdvb0fhv	15	41	-	-	HYPH
cord-279260-tdvb0fhv	15	42	CoV	CoV	NNP
cord-279260-tdvb0fhv	15	43	,	,	,
cord-279260-tdvb0fhv	15	44	SARS	SARS	NNP
cord-279260-tdvb0fhv	15	45	-	-	HYPH
cord-279260-tdvb0fhv	15	46	CoV	CoV	NNP
cord-279260-tdvb0fhv	15	47	and	and	CC
cord-279260-tdvb0fhv	15	48	other	other	JJ
cord-279260-tdvb0fhv	15	49	viruses	virus	NNS
cord-279260-tdvb0fhv	16	1	(	(	-LRB-
cord-279260-tdvb0fhv	16	2	Figure	figure	NN
cord-279260-tdvb0fhv	16	3	1	1	CD
cord-279260-tdvb0fhv	16	4	)	)	-RRB-
cord-279260-tdvb0fhv	16	5	.	.	.
cord-279260-tdvb0fhv	17	1	It	-PRON-	PRP
cord-279260-tdvb0fhv	17	2	is	be	VBZ
cord-279260-tdvb0fhv	17	3	highly	highly	RB
cord-279260-tdvb0fhv	17	4	desirable	desirable	JJ
cord-279260-tdvb0fhv	17	5	that	that	IN
cord-279260-tdvb0fhv	17	6	a	a	DT
cord-279260-tdvb0fhv	17	7	potential	potential	JJ
cord-279260-tdvb0fhv	17	8	vaccine	vaccine	NN
cord-279260-tdvb0fhv	17	9	will	will	MD
cord-279260-tdvb0fhv	17	10	induce	induce	VB
cord-279260-tdvb0fhv	17	11	a	a	DT
cord-279260-tdvb0fhv	17	12	potent	potent	JJ
cord-279260-tdvb0fhv	17	13	antibody	antibody	NN
cord-279260-tdvb0fhv	17	14	response	response	NN
cord-279260-tdvb0fhv	17	15	as	as	RB
cord-279260-tdvb0fhv	17	16	well	well	RB
cord-279260-tdvb0fhv	17	17	as	as	IN
cord-279260-tdvb0fhv	17	18	long	long	JJ
cord-279260-tdvb0fhv	17	19	-	-	HYPH
cord-279260-tdvb0fhv	17	20	term	term	NN
cord-279260-tdvb0fhv	17	21	.	.	.
cord-279260-tdvb0fhv	18	1	Identifying	identify	VBG
cord-279260-tdvb0fhv	18	2	the	the	DT
cord-279260-tdvb0fhv	18	3	epitopes	epitope	NNS
cord-279260-tdvb0fhv	18	4	that	that	WDT
cord-279260-tdvb0fhv	18	5	are	be	VBP
cord-279260-tdvb0fhv	18	6	targeted	target	VBN
cord-279260-tdvb0fhv	18	7	by	by	IN
cord-279260-tdvb0fhv	18	8	these	these	DT
cord-279260-tdvb0fhv	18	9	antibodies	antibody	NNS
cord-279260-tdvb0fhv	18	10	will	will	MD
cord-279260-tdvb0fhv	18	11	be	be	VB
cord-279260-tdvb0fhv	18	12	crucial	crucial	JJ
cord-279260-tdvb0fhv	18	13	to	to	TO
cord-279260-tdvb0fhv	18	14	determine	determine	VB
cord-279260-tdvb0fhv	18	15	the	the	DT
cord-279260-tdvb0fhv	18	16	antigenic	antigenic	JJ
cord-279260-tdvb0fhv	18	17	sites	site	NNS
cord-279260-tdvb0fhv	18	18	on	on	IN
cord-279260-tdvb0fhv	18	19	the	the	DT
cord-279260-tdvb0fhv	18	20	spike	spike	NN
cord-279260-tdvb0fhv	18	21	of	of	IN
cord-279260-tdvb0fhv	18	22	SARS	SARS	NNP
cord-279260-tdvb0fhv	18	23	-	-	HYPH
cord-279260-tdvb0fhv	18	24	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	18	25	.	.	.
cord-279260-tdvb0fhv	19	1	Although	although	IN
cord-279260-tdvb0fhv	19	2	traditionally	traditionally	RB
cord-279260-tdvb0fhv	19	3	an	an	DT
cord-279260-tdvb0fhv	19	4	effective	effective	JJ
cord-279260-tdvb0fhv	19	5	vaccine	vaccine	NN
cord-279260-tdvb0fhv	19	6	should	should	MD
cord-279260-tdvb0fhv	19	7	mainly	mainly	RB
cord-279260-tdvb0fhv	19	8	aim	aim	VB
cord-279260-tdvb0fhv	19	9	to	to	TO
cord-279260-tdvb0fhv	19	10	elicit	elicit	VB
cord-279260-tdvb0fhv	19	11	a	a	DT
cord-279260-tdvb0fhv	19	12	high	high	JJ
cord-279260-tdvb0fhv	19	13	titer	titer	NN
cord-279260-tdvb0fhv	19	14	of	of	IN
cord-279260-tdvb0fhv	19	15	neutralizing	neutralize	VBG
cord-279260-tdvb0fhv	19	16	antibodies	antibody	NNS
cord-279260-tdvb0fhv	19	17	,	,	,
cord-279260-tdvb0fhv	19	18	it	-PRON-	PRP
cord-279260-tdvb0fhv	19	19	was	be	VBD
cord-279260-tdvb0fhv	19	20	found	find	VBN
cord-279260-tdvb0fhv	19	21	that	that	IN
cord-279260-tdvb0fhv	19	22	some	some	DT
cord-279260-tdvb0fhv	19	23	non	non	AFX
cord-279260-tdvb0fhv	19	24	-	-	JJ
cord-279260-tdvb0fhv	19	25	neutralizing	neutralize	VBG
cord-279260-tdvb0fhv	19	26	antibodies	antibody	NNS
cord-279260-tdvb0fhv	19	27	could	could	MD
cord-279260-tdvb0fhv	19	28	provide	provide	VB
cord-279260-tdvb0fhv	19	29	in	in	IN
cord-279260-tdvb0fhv	19	30	vivo	vivo	NN
cord-279260-tdvb0fhv	19	31	protection	protection	NN
cord-279260-tdvb0fhv	19	32	through	through	IN
cord-279260-tdvb0fhv	19	33	antibody	antibody	NN
cord-279260-tdvb0fhv	19	34	dependent	dependent	JJ
cord-279260-tdvb0fhv	19	35	cell	cell	NN
cord-279260-tdvb0fhv	19	36	-	-	HYPH
cord-279260-tdvb0fhv	19	37	mediated	mediate	VBN
cord-279260-tdvb0fhv	19	38	cytotoxicity	cytotoxicity	NN
cord-279260-tdvb0fhv	19	39	(	(	-LRB-
cord-279260-tdvb0fhv	19	40	ADCC	ADCC	NNP
cord-279260-tdvb0fhv	19	41	)	)	-RRB-
cord-279260-tdvb0fhv	19	42	[	[	-LRB-
cord-279260-tdvb0fhv	19	43	15	15	CD
cord-279260-tdvb0fhv	19	44	]	]	-RRB-
cord-279260-tdvb0fhv	19	45	.	.	.
cord-279260-tdvb0fhv	20	1	Thus	thus	RB
cord-279260-tdvb0fhv	20	2	,	,	,
cord-279260-tdvb0fhv	20	3	it	-PRON-	PRP
cord-279260-tdvb0fhv	20	4	will	will	MD
cord-279260-tdvb0fhv	20	5	be	be	VB
cord-279260-tdvb0fhv	20	6	interesting	interesting	JJ
cord-279260-tdvb0fhv	20	7	to	to	TO
cord-279260-tdvb0fhv	20	8	distinguish	distinguish	VB
cord-279260-tdvb0fhv	20	9	the	the	DT
cord-279260-tdvb0fhv	20	10	functions	function	NNS
cord-279260-tdvb0fhv	20	11	of	of	IN
cord-279260-tdvb0fhv	20	12	the	the	DT
cord-279260-tdvb0fhv	20	13	antibodies	antibody	NNS
cord-279260-tdvb0fhv	20	14	isolated	isolate	VBN
cord-279260-tdvb0fhv	20	15	from	from	IN
cord-279260-tdvb0fhv	20	16	volunteers	volunteer	NNS
cord-279260-tdvb0fhv	20	17	in	in	IN
cord-279260-tdvb0fhv	20	18	clinical	clinical	JJ
cord-279260-tdvb0fhv	20	19	trials	trial	NNS
cord-279260-tdvb0fhv	20	20	in	in	IN
cord-279260-tdvb0fhv	20	21	order	order	NN
cord-279260-tdvb0fhv	20	22	to	to	TO
cord-279260-tdvb0fhv	20	23	understand	understand	VB
cord-279260-tdvb0fhv	20	24	in	in	IN
cord-279260-tdvb0fhv	20	25	molecular	molecular	JJ
cord-279260-tdvb0fhv	20	26	terms	term	NNS
cord-279260-tdvb0fhv	20	27	vaccines	vaccine	NNS
cord-279260-tdvb0fhv	20	28	'	'	POS
cord-279260-tdvb0fhv	20	29	effectiveness	effectiveness	NN
cord-279260-tdvb0fhv	20	30	.	.	.
cord-279260-tdvb0fhv	21	1	It	-PRON-	PRP
cord-279260-tdvb0fhv	21	2	is	be	VBZ
cord-279260-tdvb0fhv	21	3	also	also	RB
cord-279260-tdvb0fhv	21	4	important	important	JJ
cord-279260-tdvb0fhv	21	5	to	to	TO
cord-279260-tdvb0fhv	21	6	note	note	VB
cord-279260-tdvb0fhv	21	7	that	that	IN
cord-279260-tdvb0fhv	21	8	T	t	NN
cord-279260-tdvb0fhv	21	9	-	-	HYPH
cord-279260-tdvb0fhv	21	10	cell	cell	NN
cord-279260-tdvb0fhv	21	11	immunity	immunity	NN
cord-279260-tdvb0fhv	21	12	was	be	VBD
cord-279260-tdvb0fhv	21	13	found	find	VBN
cord-279260-tdvb0fhv	21	14	to	to	TO
cord-279260-tdvb0fhv	21	15	be	be	VB
cord-279260-tdvb0fhv	21	16	elicited	elicit	VBN
cord-279260-tdvb0fhv	21	17	by	by	IN
cord-279260-tdvb0fhv	21	18	SARS	SARS	NNP
cord-279260-tdvb0fhv	21	19	-	-	HYPH
cord-279260-tdvb0fhv	21	20	CoV	CoV	NNP
cord-279260-tdvb0fhv	21	21	or	or	CC
cord-279260-tdvb0fhv	21	22	MERS	MERS	NNP
cord-279260-tdvb0fhv	21	23	-	-	HYPH
cord-279260-tdvb0fhv	21	24	CoV	cov	NN
cord-279260-tdvb0fhv	21	25	DNA	dna	NN
cord-279260-tdvb0fhv	21	26	vaccines	vaccine	NNS
cord-279260-tdvb0fhv	21	27	(	(	-LRB-
cord-279260-tdvb0fhv	21	28	both	both	DT
cord-279260-tdvb0fhv	21	29	express	express	VBP
cord-279260-tdvb0fhv	21	30	trimeric	trimeric	NNP
cord-279260-tdvb0fhv	21	31	spike	spike	NN
cord-279260-tdvb0fhv	21	32	protein	protein	NN
cord-279260-tdvb0fhv	21	33	)	)	-RRB-
cord-279260-tdvb0fhv	21	34	[	[	-LRB-
cord-279260-tdvb0fhv	21	35	7	7	CD
cord-279260-tdvb0fhv	21	36	,	,	,
cord-279260-tdvb0fhv	21	37	9	9	CD
cord-279260-tdvb0fhv	21	38	]	]	-RRB-
cord-279260-tdvb0fhv	21	39	.	.	.
cord-279260-tdvb0fhv	22	1	These	these	DT
cord-279260-tdvb0fhv	22	2	results	result	NNS
cord-279260-tdvb0fhv	22	3	imply	imply	VBP
cord-279260-tdvb0fhv	22	4	that	that	IN
cord-279260-tdvb0fhv	22	5	using	use	VBG
cord-279260-tdvb0fhv	22	6	SARS	SARS	NNP
cord-279260-tdvb0fhv	22	7	-	-	HYPH
cord-279260-tdvb0fhv	22	8	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	22	9	spike	spike	NN
cord-279260-tdvb0fhv	22	10	protein	protein	NN
cord-279260-tdvb0fhv	22	11	as	as	IN
cord-279260-tdvb0fhv	22	12	immunogen	immunogen	NN
cord-279260-tdvb0fhv	22	13	may	may	MD
cord-279260-tdvb0fhv	22	14	also	also	RB
cord-279260-tdvb0fhv	22	15	elicit	elicit	VB
cord-279260-tdvb0fhv	22	16	cellular	cellular	JJ
cord-279260-tdvb0fhv	22	17	immune	immune	JJ
cord-279260-tdvb0fhv	22	18	response	response	NN
cord-279260-tdvb0fhv	22	19	,	,	,
cord-279260-tdvb0fhv	22	20	in	in	IN
cord-279260-tdvb0fhv	22	21	addition	addition	NN
cord-279260-tdvb0fhv	22	22	to	to	IN
cord-279260-tdvb0fhv	22	23	humoral	humoral	JJ
cord-279260-tdvb0fhv	22	24	immune	immune	JJ
cord-279260-tdvb0fhv	22	25	response	response	NN
cord-279260-tdvb0fhv	22	26	.	.	.
cord-279260-tdvb0fhv	23	1	There	there	EX
cord-279260-tdvb0fhv	23	2	is	be	VBZ
cord-279260-tdvb0fhv	23	3	a	a	DT
cord-279260-tdvb0fhv	23	4	concern	concern	NN
cord-279260-tdvb0fhv	23	5	that	that	IN
cord-279260-tdvb0fhv	23	6	some	some	DT
cord-279260-tdvb0fhv	23	7	antibodies	antibody	NNS
cord-279260-tdvb0fhv	23	8	elicited	elicit	VBN
cord-279260-tdvb0fhv	23	9	by	by	IN
cord-279260-tdvb0fhv	23	10	the	the	DT
cord-279260-tdvb0fhv	23	11	SARS	SARS	NNP
cord-279260-tdvb0fhv	23	12	-	-	HYPH
cord-279260-tdvb0fhv	23	13	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	23	14	vaccine	vaccine	NN
cord-279260-tdvb0fhv	23	15	may	may	MD
cord-279260-tdvb0fhv	23	16	cause	cause	VB
cord-279260-tdvb0fhv	23	17	an	an	DT
cord-279260-tdvb0fhv	23	18	adverse	adverse	JJ
cord-279260-tdvb0fhv	23	19	effect	effect	NN
cord-279260-tdvb0fhv	23	20	such	such	JJ
cord-279260-tdvb0fhv	23	21	as	as	IN
cord-279260-tdvb0fhv	23	22	antibody	antibody	NN
cord-279260-tdvb0fhv	23	23	-	-	HYPH
cord-279260-tdvb0fhv	23	24	dependent	dependent	JJ
cord-279260-tdvb0fhv	23	25	enhancement	enhancement	NN
cord-279260-tdvb0fhv	23	26	(	(	-LRB-
cord-279260-tdvb0fhv	23	27	ADE	ADE	NNP
cord-279260-tdvb0fhv	23	28	)	)	-RRB-
cord-279260-tdvb0fhv	23	29	or	or	CC
cord-279260-tdvb0fhv	23	30	enhanced	enhance	VBN
cord-279260-tdvb0fhv	23	31	respiratory	respiratory	JJ
cord-279260-tdvb0fhv	23	32	disease	disease	NN
cord-279260-tdvb0fhv	23	33	(	(	-LRB-
cord-279260-tdvb0fhv	23	34	ERD	ERD	NNP
cord-279260-tdvb0fhv	23	35	)	)	-RRB-
cord-279260-tdvb0fhv	23	36	[	[	-LRB-
cord-279260-tdvb0fhv	23	37	suggesting	suggest	VBG
cord-279260-tdvb0fhv	23	38	such	such	PDT
cord-279260-tdvb0fhv	23	39	a	a	DT
cord-279260-tdvb0fhv	23	40	potential	potential	JJ
cord-279260-tdvb0fhv	23	41	complication	complication	NN
cord-279260-tdvb0fhv	23	42	may	may	MD
cord-279260-tdvb0fhv	23	43	not	not	RB
cord-279260-tdvb0fhv	23	44	be	be	VB
cord-279260-tdvb0fhv	23	45	a	a	DT
cord-279260-tdvb0fhv	23	46	concern	concern	NN
cord-279260-tdvb0fhv	23	47	,	,	,
cord-279260-tdvb0fhv	23	48	at	at	IN
cord-279260-tdvb0fhv	23	49	least	least	JJS
cord-279260-tdvb0fhv	23	50	for	for	IN
cord-279260-tdvb0fhv	23	51	RBD	RBD	NNP
cord-279260-tdvb0fhv	23	52	-	-	HYPH
cord-279260-tdvb0fhv	23	53	based	base	VBN
cord-279260-tdvb0fhv	23	54	SARS	SARS	NNP
cord-279260-tdvb0fhv	23	55	-	-	HYPH
cord-279260-tdvb0fhv	23	56	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	23	57	vaccine	vaccine	NN
cord-279260-tdvb0fhv	23	58	development	development	NN
cord-279260-tdvb0fhv	23	59	[	[	-LRB-
cord-279260-tdvb0fhv	23	60	23	23	CD
cord-279260-tdvb0fhv	23	61	]	]	-RRB-
cord-279260-tdvb0fhv	23	62	.	.	.
cord-279260-tdvb0fhv	24	1	To	to	TO
cord-279260-tdvb0fhv	24	2	enhance	enhance	VB
cord-279260-tdvb0fhv	24	3	the	the	DT
cord-279260-tdvb0fhv	24	4	magnitude	magnitude	NN
cord-279260-tdvb0fhv	24	5	and	and	CC
cord-279260-tdvb0fhv	24	6	quality	quality	NN
cord-279260-tdvb0fhv	24	7	of	of	IN
cord-279260-tdvb0fhv	24	8	the	the	DT
cord-279260-tdvb0fhv	24	9	adaptive	adaptive	JJ
cord-279260-tdvb0fhv	24	10	response	response	NN
cord-279260-tdvb0fhv	24	11	,	,	,
cord-279260-tdvb0fhv	24	12	adjuvants	adjuvant	NNS
cord-279260-tdvb0fhv	24	13	are	be	VBP
cord-279260-tdvb0fhv	24	14	included	include	VBN
cord-279260-tdvb0fhv	24	15	in	in	IN
cord-279260-tdvb0fhv	24	16	some	some	DT
cord-279260-tdvb0fhv	24	17	vaccination	vaccination	NN
cord-279260-tdvb0fhv	24	18	formulations	formulation	NNS
cord-279260-tdvb0fhv	24	19	[	[	-LRB-
cord-279260-tdvb0fhv	24	20	24	24	CD
cord-279260-tdvb0fhv	24	21	]	]	-RRB-
cord-279260-tdvb0fhv	24	22	.	.	.
cord-279260-tdvb0fhv	25	1	Different	different	JJ
cord-279260-tdvb0fhv	25	2	adjuvants	adjuvant	NNS
cord-279260-tdvb0fhv	25	3	drive	drive	VBP
cord-279260-tdvb0fhv	25	4	different	different	JJ
cord-279260-tdvb0fhv	25	5	immunological	immunological	JJ
cord-279260-tdvb0fhv	25	6	signatures	signature	NNS
cord-279260-tdvb0fhv	25	7	and	and	CC
cord-279260-tdvb0fhv	25	8	,	,	,
cord-279260-tdvb0fhv	25	9	hence	hence	RB
cord-279260-tdvb0fhv	25	10	,	,	,
cord-279260-tdvb0fhv	25	11	are	be	VBP
cord-279260-tdvb0fhv	25	12	optimal	optimal	JJ
cord-279260-tdvb0fhv	25	13	for	for	IN
cord-279260-tdvb0fhv	25	14	protection	protection	NN
cord-279260-tdvb0fhv	25	15	against	against	IN
cord-279260-tdvb0fhv	25	16	different	different	JJ
cord-279260-tdvb0fhv	25	17	pathogens	pathogen	NNS
cord-279260-tdvb0fhv	25	18	[	[	-LRB-
cord-279260-tdvb0fhv	25	19	25	25	CD
cord-279260-tdvb0fhv	25	20	]	]	-RRB-
cord-279260-tdvb0fhv	25	21	.	.	.
cord-279260-tdvb0fhv	26	1	For	for	IN
cord-279260-tdvb0fhv	26	2	example	example	NN
cord-279260-tdvb0fhv	26	3	,	,	,
cord-279260-tdvb0fhv	26	4	adjuvants	adjuvant	NNS
cord-279260-tdvb0fhv	26	5	can	can	MD
cord-279260-tdvb0fhv	26	6	modulate	modulate	VB
cord-279260-tdvb0fhv	26	7	the	the	DT
cord-279260-tdvb0fhv	26	8	ratio	ratio	NN
cord-279260-tdvb0fhv	26	9	of	of	IN
cord-279260-tdvb0fhv	26	10	T	T	NNP
cord-279260-tdvb0fhv	26	11	helper	helper	NN
cord-279260-tdvb0fhv	26	12	1	1	CD
cord-279260-tdvb0fhv	26	13	(	(	-LRB-
cord-279260-tdvb0fhv	26	14	Th1	Th1	NNP
cord-279260-tdvb0fhv	26	15	)	)	-RRB-
cord-279260-tdvb0fhv	26	16	and	and	CC
cord-279260-tdvb0fhv	26	17	T	T	NNP
cord-279260-tdvb0fhv	26	18	helper	helper	NN
cord-279260-tdvb0fhv	26	19	2	2	CD
cord-279260-tdvb0fhv	27	1	(	(	-LRB-
cord-279260-tdvb0fhv	27	2	Th2	Th2	NNP
cord-279260-tdvb0fhv	27	3	)	)	-RRB-
cord-279260-tdvb0fhv	27	4	responses	response	NNS
cord-279260-tdvb0fhv	27	5	,	,	,
cord-279260-tdvb0fhv	27	6	increase	increase	VB
cord-279260-tdvb0fhv	27	7	the	the	DT
cord-279260-tdvb0fhv	27	8	generation	generation	NN
cord-279260-tdvb0fhv	27	9	of	of	IN
cord-279260-tdvb0fhv	27	10	memory	memory	NN
cord-279260-tdvb0fhv	27	11	cells	cell	NNS
cord-279260-tdvb0fhv	27	12	,	,	,
cord-279260-tdvb0fhv	27	13	and	and	CC
cord-279260-tdvb0fhv	27	14	alter	alter	VB
cord-279260-tdvb0fhv	27	15	the	the	DT
cord-279260-tdvb0fhv	27	16	breadth	breadth	NN
cord-279260-tdvb0fhv	27	17	and	and	CC
cord-279260-tdvb0fhv	27	18	affinity	affinity	NN
cord-279260-tdvb0fhv	27	19	of	of	IN
cord-279260-tdvb0fhv	27	20	the	the	DT
cord-279260-tdvb0fhv	27	21	response	response	NN
cord-279260-tdvb0fhv	27	22	[	[	-LRB-
cord-279260-tdvb0fhv	27	23	24	24	CD
cord-279260-tdvb0fhv	27	24	]	]	-RRB-
cord-279260-tdvb0fhv	27	25	.	.	.
cord-279260-tdvb0fhv	28	1	Determining	determine	VBG
cord-279260-tdvb0fhv	28	2	which	which	WDT
cord-279260-tdvb0fhv	28	3	adjuvants	adjuvant	NNS
cord-279260-tdvb0fhv	28	4	can	can	MD
cord-279260-tdvb0fhv	28	5	enhance	enhance	VB
cord-279260-tdvb0fhv	28	6	protective	protective	JJ
cord-279260-tdvb0fhv	28	7	vaccine	vaccine	NN
cord-279260-tdvb0fhv	28	8	response	response	NN
cord-279260-tdvb0fhv	28	9	to	to	IN
cord-279260-tdvb0fhv	28	10	SARS	SARS	NNP
cord-279260-tdvb0fhv	28	11	-	-	HYPH
cord-279260-tdvb0fhv	28	12	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	28	13	will	will	MD
cord-279260-tdvb0fhv	28	14	be	be	VB
cord-279260-tdvb0fhv	28	15	important	important	JJ
cord-279260-tdvb0fhv	28	16	.	.	.
cord-279260-tdvb0fhv	29	1	Because	because	IN
cord-279260-tdvb0fhv	29	2	immune	immune	JJ
cord-279260-tdvb0fhv	29	3	responses	response	NNS
cord-279260-tdvb0fhv	29	4	in	in	IN
cord-279260-tdvb0fhv	29	5	different	different	JJ
cord-279260-tdvb0fhv	29	6	age	age	NN
cord-279260-tdvb0fhv	29	7	groups	group	NNS
cord-279260-tdvb0fhv	29	8	are	be	VBP
cord-279260-tdvb0fhv	29	9	not	not	RB
cord-279260-tdvb0fhv	29	10	the	the	DT
cord-279260-tdvb0fhv	29	11	same	same	JJ
cord-279260-tdvb0fhv	29	12	,	,	,
cord-279260-tdvb0fhv	29	13	optimal	optimal	JJ
cord-279260-tdvb0fhv	29	14	vaccination	vaccination	NN
cord-279260-tdvb0fhv	29	15	strategy	strategy	NN
cord-279260-tdvb0fhv	29	16	may	may	MD
cord-279260-tdvb0fhv	29	17	be	be	VB
cord-279260-tdvb0fhv	29	18	varied	varied	JJ
cord-279260-tdvb0fhv	29	19	for	for	IN
cord-279260-tdvb0fhv	29	20	different	different	JJ
cord-279260-tdvb0fhv	29	21	age	age	NN
cord-279260-tdvb0fhv	29	22	groups	group	NNS
cord-279260-tdvb0fhv	29	23	[	[	-LRB-
cord-279260-tdvb0fhv	29	24	26	26	CD
cord-279260-tdvb0fhv	29	25	]	]	-RRB-
cord-279260-tdvb0fhv	29	26	.	.	.
cord-279260-tdvb0fhv	30	1	For	for	IN
cord-279260-tdvb0fhv	30	2	example	example	NN
cord-279260-tdvb0fhv	30	3	,	,	,
cord-279260-tdvb0fhv	30	4	the	the	DT
cord-279260-tdvb0fhv	30	5	MF59-adjuvanted	MF59-adjuvanted	NNP
cord-279260-tdvb0fhv	30	6	influenza	influenza	NN
cord-279260-tdvb0fhv	30	7	vaccine	vaccine	NN
cord-279260-tdvb0fhv	30	8	,	,	,
cord-279260-tdvb0fhv	30	9	Fluad	Fluad	NNP
cord-279260-tdvb0fhv	30	10	,	,	,
cord-279260-tdvb0fhv	30	11	is	be	VBZ
cord-279260-tdvb0fhv	30	12	only	only	RB
cord-279260-tdvb0fhv	30	13	licensed	license	VBN
cord-279260-tdvb0fhv	30	14	and	and	CC
cord-279260-tdvb0fhv	30	15	approved	approve	VBN
cord-279260-tdvb0fhv	30	16	for	for	IN
cord-279260-tdvb0fhv	30	17	adults	adult	NNS
cord-279260-tdvb0fhv	30	18	aged	age	VBN
cord-279260-tdvb0fhv	30	19	65	65	CD
cord-279260-tdvb0fhv	30	20	years	year	NNS
cord-279260-tdvb0fhv	30	21	and	and	CC
cord-279260-tdvb0fhv	30	22	older	old	JJR
cord-279260-tdvb0fhv	30	23	,	,	,
cord-279260-tdvb0fhv	30	24	to	to	TO
cord-279260-tdvb0fhv	30	25	elicit	elicit	VB
cord-279260-tdvb0fhv	30	26	a	a	DT
cord-279260-tdvb0fhv	30	27	higher	high	JJR
cord-279260-tdvb0fhv	30	28	protective	protective	JJ
cord-279260-tdvb0fhv	30	29	immune	immune	JJ
cord-279260-tdvb0fhv	30	30	response	response	NN
cord-279260-tdvb0fhv	30	31	in	in	IN
cord-279260-tdvb0fhv	30	32	the	the	DT
cord-279260-tdvb0fhv	30	33	elderly	elderly	JJ
cord-279260-tdvb0fhv	30	34	This	this	DT
cord-279260-tdvb0fhv	30	35	article	article	NN
cord-279260-tdvb0fhv	30	36	is	be	VBZ
cord-279260-tdvb0fhv	30	37	protected	protect	VBN
cord-279260-tdvb0fhv	30	38	by	by	IN
cord-279260-tdvb0fhv	30	39	copyright	copyright	NN
cord-279260-tdvb0fhv	30	40	.	.	.
cord-279260-tdvb0fhv	31	1	All	all	DT
cord-279260-tdvb0fhv	31	2	rights	right	NNS
cord-279260-tdvb0fhv	31	3	reserved	reserve	VBN
cord-279260-tdvb0fhv	31	4	.	.	.
cord-279260-tdvb0fhv	32	1	(	(	-LRB-
cord-279260-tdvb0fhv	32	2	https://www.cdc.gov/flu/prevent/adjuvant.htm	https://www.cdc.gov/flu/prevent/adjuvant.htm	CD
cord-279260-tdvb0fhv	32	3	)	)	-RRB-
cord-279260-tdvb0fhv	32	4	.	.	.
cord-279260-tdvb0fhv	33	1	As	as	IN
cord-279260-tdvb0fhv	33	2	it	-PRON-	PRP
cord-279260-tdvb0fhv	33	3	is	be	VBZ
cord-279260-tdvb0fhv	33	4	clear	clear	JJ
cord-279260-tdvb0fhv	33	5	that	that	IN
cord-279260-tdvb0fhv	33	6	the	the	DT
cord-279260-tdvb0fhv	33	7	mortality	mortality	NN
cord-279260-tdvb0fhv	33	8	rate	rate	NN
cord-279260-tdvb0fhv	33	9	in	in	IN
cord-279260-tdvb0fhv	33	10	the	the	DT
cord-279260-tdvb0fhv	33	11	elderly	elderly	JJ
cord-279260-tdvb0fhv	33	12	is	be	VBZ
cord-279260-tdvb0fhv	33	13	the	the	DT
cord-279260-tdvb0fhv	33	14	highest	high	JJS
cord-279260-tdvb0fhv	33	15	among	among	IN
cord-279260-tdvb0fhv	33	16	the	the	DT
cord-279260-tdvb0fhv	33	17	COVID-19	COVID-19	NNP
cord-279260-tdvb0fhv	33	18	patients	patient	NNS
cord-279260-tdvb0fhv	33	19	,	,	,
cord-279260-tdvb0fhv	33	20	a	a	DT
cord-279260-tdvb0fhv	33	21	specific	specific	JJ
cord-279260-tdvb0fhv	33	22	vaccination	vaccination	NN
cord-279260-tdvb0fhv	33	23	strategy	strategy	NN
cord-279260-tdvb0fhv	33	24	for	for	IN
cord-279260-tdvb0fhv	33	25	this	this	DT
cord-279260-tdvb0fhv	33	26	group	group	NN
cord-279260-tdvb0fhv	33	27	will	will	MD
cord-279260-tdvb0fhv	33	28	need	need	VB
cord-279260-tdvb0fhv	33	29	to	to	TO
cord-279260-tdvb0fhv	33	30	be	be	VB
cord-279260-tdvb0fhv	33	31	considered	consider	VBN
cord-279260-tdvb0fhv	33	32	during	during	IN
cord-279260-tdvb0fhv	33	33	vaccine	vaccine	NN
cord-279260-tdvb0fhv	33	34	development	development	NN
cord-279260-tdvb0fhv	33	35	.	.	.
cord-279260-tdvb0fhv	34	1	To	to	TO
cord-279260-tdvb0fhv	34	2	accelerate	accelerate	VB
cord-279260-tdvb0fhv	34	3	vaccine	vaccine	NN
cord-279260-tdvb0fhv	34	4	development	development	NN
cord-279260-tdvb0fhv	34	5	,	,	,
cord-279260-tdvb0fhv	34	6	animal	animal	NN
cord-279260-tdvb0fhv	34	7	infection	infection	NN
cord-279260-tdvb0fhv	34	8	models	model	NNS
cord-279260-tdvb0fhv	34	9	for	for	IN
cord-279260-tdvb0fhv	34	10	SARS	SARS	NNP
cord-279260-tdvb0fhv	34	11	-	-	HYPH
cord-279260-tdvb0fhv	34	12	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	34	13	are	be	VBP
cord-279260-tdvb0fhv	34	14	needed	need	VBN
cord-279260-tdvb0fhv	34	15	.	.	.
cord-279260-tdvb0fhv	35	1	Although	although	IN
cord-279260-tdvb0fhv	35	2	macaques	macaque	NNS
cord-279260-tdvb0fhv	35	3	show	show	VBP
cord-279260-tdvb0fhv	35	4	COVID-19-like	COVID-19-like	NNP
cord-279260-tdvb0fhv	35	5	disease	disease	NN
cord-279260-tdvb0fhv	35	6	upon	upon	IN
cord-279260-tdvb0fhv	35	7	SARS	SARS	NNP
cord-279260-tdvb0fhv	35	8	-	-	HYPH
cord-279260-tdvb0fhv	35	9	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	35	10	infection	infection	NN
cord-279260-tdvb0fhv	35	11	,	,	,
cord-279260-tdvb0fhv	35	12	the	the	DT
cord-279260-tdvb0fhv	35	13	non	non	JJ
cord-279260-tdvb0fhv	35	14	-	-	JJ
cord-279260-tdvb0fhv	35	15	human	human	JJ
cord-279260-tdvb0fhv	35	16	primate	primate	NN
cord-279260-tdvb0fhv	35	17	model	model	NN
cord-279260-tdvb0fhv	35	18	is	be	VBZ
cord-279260-tdvb0fhv	35	19	usually	usually	RB
cord-279260-tdvb0fhv	35	20	not	not	RB
cord-279260-tdvb0fhv	35	21	readily	readily	RB
cord-279260-tdvb0fhv	35	22	accessible	accessible	JJ
cord-279260-tdvb0fhv	35	23	to	to	IN
cord-279260-tdvb0fhv	35	24	most	most	JJS
cord-279260-tdvb0fhv	35	25	laboratories	laboratory	NNS
cord-279260-tdvb0fhv	35	26	[	[	-LRB-
cord-279260-tdvb0fhv	35	27	27	27	CD
cord-279260-tdvb0fhv	35	28	]	]	-RRB-
cord-279260-tdvb0fhv	35	29	.	.	.
cord-279260-tdvb0fhv	36	1	Ferrets	ferret	NNS
cord-279260-tdvb0fhv	36	2	and	and	CC
cord-279260-tdvb0fhv	36	3	golden	golden	JJ
cord-279260-tdvb0fhv	36	4	Syrian	syrian	JJ
cord-279260-tdvb0fhv	36	5	hamster	hamster	NN
cord-279260-tdvb0fhv	36	6	are	be	VBP
cord-279260-tdvb0fhv	36	7	presented	present	VBN
cord-279260-tdvb0fhv	36	8	as	as	IN
cord-279260-tdvb0fhv	36	9	alternatives	alternative	NNS
cord-279260-tdvb0fhv	36	10	,	,	,
cord-279260-tdvb0fhv	36	11	as	as	IN
cord-279260-tdvb0fhv	36	12	all	all	DT
cord-279260-tdvb0fhv	36	13	show	show	VBP
cord-279260-tdvb0fhv	36	14	mild	mild	JJ
cord-279260-tdvb0fhv	36	15	disease	disease	NN
cord-279260-tdvb0fhv	36	16	signs	sign	NNS
cord-279260-tdvb0fhv	36	17	and	and	CC
cord-279260-tdvb0fhv	36	18	virus	virus	NN
cord-279260-tdvb0fhv	36	19	shedding	shed	VBG
cord-279260-tdvb0fhv	36	20	after	after	IN
cord-279260-tdvb0fhv	36	21	challenge	challenge	NN
cord-279260-tdvb0fhv	36	22	with	with	IN
cord-279260-tdvb0fhv	36	23	SARS	SARS	NNP
cord-279260-tdvb0fhv	36	24	-	-	HYPH
cord-279260-tdvb0fhv	36	25	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	36	26	[	[	-LRB-
cord-279260-tdvb0fhv	36	27	28	28	CD
cord-279260-tdvb0fhv	36	28	,	,	,
cord-279260-tdvb0fhv	36	29	29	29	CD
cord-279260-tdvb0fhv	36	30	]	]	-RRB-
cord-279260-tdvb0fhv	36	31	,	,	,
cord-279260-tdvb0fhv	36	32	and	and	CC
cord-279260-tdvb0fhv	36	33	are	be	VBP
cord-279260-tdvb0fhv	36	34	usually	usually	RB
cord-279260-tdvb0fhv	36	35	more	more	RBR
cord-279260-tdvb0fhv	36	36	widely	widely	RB
cord-279260-tdvb0fhv	36	37	available	available	JJ
cord-279260-tdvb0fhv	36	38	than	than	IN
cord-279260-tdvb0fhv	36	39	non	non	JJ
cord-279260-tdvb0fhv	36	40	-	-	JJ
cord-279260-tdvb0fhv	36	41	human	human	JJ
cord-279260-tdvb0fhv	36	42	primates	primate	NNS
cord-279260-tdvb0fhv	36	43	.	.	.
cord-279260-tdvb0fhv	37	1	Nonetheless	nonetheless	RB
cord-279260-tdvb0fhv	37	2	,	,	,
cord-279260-tdvb0fhv	37	3	mouse	mouse	NN
cord-279260-tdvb0fhv	37	4	is	be	VBZ
cord-279260-tdvb0fhv	37	5	the	the	DT
cord-279260-tdvb0fhv	37	6	most	most	RBS
cord-279260-tdvb0fhv	37	7	commonly	commonly	RB
cord-279260-tdvb0fhv	37	8	used	use	VBN
cord-279260-tdvb0fhv	37	9	animal	animal	NN
cord-279260-tdvb0fhv	37	10	model	model	NN
cord-279260-tdvb0fhv	37	11	during	during	IN
cord-279260-tdvb0fhv	37	12	vaccine	vaccine	NN
cord-279260-tdvb0fhv	37	13	development	development	NN
cord-279260-tdvb0fhv	37	14	in	in	IN
cord-279260-tdvb0fhv	37	15	general	general	JJ
cord-279260-tdvb0fhv	37	16	.	.	.
cord-279260-tdvb0fhv	38	1	Although	although	IN
cord-279260-tdvb0fhv	38	2	wild	wild	JJ
cord-279260-tdvb0fhv	38	3	type	type	NN
cord-279260-tdvb0fhv	38	4	mouse	mouse	NN
cord-279260-tdvb0fhv	38	5	is	be	VBZ
cord-279260-tdvb0fhv	38	6	not	not	RB
cord-279260-tdvb0fhv	38	7	susceptible	susceptible	JJ
cord-279260-tdvb0fhv	38	8	to	to	IN
cord-279260-tdvb0fhv	38	9	the	the	DT
cord-279260-tdvb0fhv	38	10	infection	infection	NN
cord-279260-tdvb0fhv	38	11	of	of	IN
cord-279260-tdvb0fhv	38	12	SARS	SARS	NNP
cord-279260-tdvb0fhv	38	13	-	-	HYPH
cord-279260-tdvb0fhv	38	14	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	38	15	,	,	,
cord-279260-tdvb0fhv	38	16	transgenic	transgenic	JJ
cord-279260-tdvb0fhv	38	17	mice	mouse	NNS
cord-279260-tdvb0fhv	38	18	that	that	WDT
cord-279260-tdvb0fhv	38	19	express	express	VBP
cord-279260-tdvb0fhv	38	20	the	the	DT
cord-279260-tdvb0fhv	38	21	human	human	JJ
cord-279260-tdvb0fhv	38	22	angiotensin	angiotensin	NN
cord-279260-tdvb0fhv	38	23	-	-	HYPH
cord-279260-tdvb0fhv	38	24	converting	convert	VBG
cord-279260-tdvb0fhv	38	25	enzyme	enzyme	NN
cord-279260-tdvb0fhv	38	26	2	2	CD
cord-279260-tdvb0fhv	39	1	(	(	-LRB-
cord-279260-tdvb0fhv	39	2	hACE2	hace2	NN
cord-279260-tdvb0fhv	39	3	)	)	-RRB-
cord-279260-tdvb0fhv	39	4	receptor	receptor	NN
cord-279260-tdvb0fhv	39	5	,	,	,
cord-279260-tdvb0fhv	39	6	which	which	WDT
cord-279260-tdvb0fhv	39	7	was	be	VBD
cord-279260-tdvb0fhv	39	8	previously	previously	RB
cord-279260-tdvb0fhv	39	9	established	establish	VBN
cord-279260-tdvb0fhv	39	10	for	for	IN
cord-279260-tdvb0fhv	39	11	SARS	SARS	NNP
cord-279260-tdvb0fhv	39	12	-	-	HYPH
cord-279260-tdvb0fhv	39	13	CoV	CoV	NNP
cord-279260-tdvb0fhv	39	14	study	study	NN
cord-279260-tdvb0fhv	39	15	[	[	-LRB-
cord-279260-tdvb0fhv	39	16	30	30	CD
cord-279260-tdvb0fhv	39	17	]	]	-RRB-
cord-279260-tdvb0fhv	39	18	,	,	,
cord-279260-tdvb0fhv	39	19	showed	show	VBD
cord-279260-tdvb0fhv	39	20	significant	significant	JJ
cord-279260-tdvb0fhv	39	21	pathogenicity	pathogenicity	NN
cord-279260-tdvb0fhv	39	22	upon	upon	IN
cord-279260-tdvb0fhv	39	23	the	the	DT
cord-279260-tdvb0fhv	39	24	infections	infection	NNS
cord-279260-tdvb0fhv	39	25	of	of	IN
cord-279260-tdvb0fhv	39	26	SARS	SARS	NNP
cord-279260-tdvb0fhv	39	27	-	-	HYPH
cord-279260-tdvb0fhv	39	28	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	39	29	[	[	-LRB-
cord-279260-tdvb0fhv	39	30	31	31	CD
cord-279260-tdvb0fhv	39	31	]	]	-RRB-
cord-279260-tdvb0fhv	39	32	.	.	.
cord-279260-tdvb0fhv	40	1	Expressing	express	VBG
cord-279260-tdvb0fhv	40	2	hACE2	hace2	UH
cord-279260-tdvb0fhv	40	3	through	through	IN
cord-279260-tdvb0fhv	40	4	adenoviral	adenoviral	JJ
cord-279260-tdvb0fhv	40	5	transduction	transduction	NN
cord-279260-tdvb0fhv	40	6	may	may	MD
cord-279260-tdvb0fhv	40	7	provide	provide	VB
cord-279260-tdvb0fhv	40	8	another	another	DT
cord-279260-tdvb0fhv	40	9	possible	possible	JJ
cord-279260-tdvb0fhv	40	10	approach	approach	NN
cord-279260-tdvb0fhv	40	11	to	to	TO
cord-279260-tdvb0fhv	40	12	generate	generate	VB
cord-279260-tdvb0fhv	40	13	a	a	DT
cord-279260-tdvb0fhv	40	14	mouse	mouse	NN
cord-279260-tdvb0fhv	40	15	model	model	NN
cord-279260-tdvb0fhv	40	16	for	for	IN
cord-279260-tdvb0fhv	40	17	SARs	SARs	NNP
cord-279260-tdvb0fhv	40	18	-	-	:
cord-279260-tdvb0fhv	40	19	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	40	20	infection	infection	NN
cord-279260-tdvb0fhv	40	21	.	.	.
cord-279260-tdvb0fhv	41	1	The	the	DT
cord-279260-tdvb0fhv	41	2	feasibility	feasibility	NN
cord-279260-tdvb0fhv	41	3	of	of	IN
cord-279260-tdvb0fhv	41	4	this	this	DT
cord-279260-tdvb0fhv	41	5	approach	approach	NN
cord-279260-tdvb0fhv	41	6	is	be	VBZ
cord-279260-tdvb0fhv	41	7	suggested	suggest	VBN
cord-279260-tdvb0fhv	41	8	by	by	IN
cord-279260-tdvb0fhv	41	9	a	a	DT
cord-279260-tdvb0fhv	41	10	previous	previous	JJ
cord-279260-tdvb0fhv	41	11	study	study	NN
cord-279260-tdvb0fhv	41	12	that	that	WDT
cord-279260-tdvb0fhv	41	13	used	use	VBD
cord-279260-tdvb0fhv	41	14	adenoviral	adenoviral	JJ
cord-279260-tdvb0fhv	41	15	transduction	transduction	NN
cord-279260-tdvb0fhv	41	16	to	to	TO
cord-279260-tdvb0fhv	41	17	generate	generate	VB
cord-279260-tdvb0fhv	41	18	a	a	DT
cord-279260-tdvb0fhv	41	19	mouse	mouse	NN
cord-279260-tdvb0fhv	41	20	model	model	NN
cord-279260-tdvb0fhv	41	21	for	for	IN
cord-279260-tdvb0fhv	41	22	MERS	MERS	NNP
cord-279260-tdvb0fhv	41	23	-	-	HYPH
cord-279260-tdvb0fhv	41	24	CoV	CoV	NNP
cord-279260-tdvb0fhv	41	25	infection	infection	NN
cord-279260-tdvb0fhv	41	26	[	[	-LRB-
cord-279260-tdvb0fhv	41	27	32	32	CD
cord-279260-tdvb0fhv	41	28	]	]	-RRB-
cord-279260-tdvb0fhv	41	29	.	.	.
cord-279260-tdvb0fhv	42	1	The	the	DT
cord-279260-tdvb0fhv	42	2	advantage	advantage	NN
cord-279260-tdvb0fhv	42	3	of	of	IN
cord-279260-tdvb0fhv	42	4	this	this	DT
cord-279260-tdvb0fhv	42	5	approach	approach	NN
cord-279260-tdvb0fhv	42	6	is	be	VBZ
cord-279260-tdvb0fhv	42	7	that	that	IN
cord-279260-tdvb0fhv	42	8	it	-PRON-	PRP
cord-279260-tdvb0fhv	42	9	can	can	MD
cord-279260-tdvb0fhv	42	10	be	be	VB
cord-279260-tdvb0fhv	42	11	applied	apply	VBN
cord-279260-tdvb0fhv	42	12	to	to	IN
cord-279260-tdvb0fhv	42	13	multiple	multiple	JJ
cord-279260-tdvb0fhv	42	14	genetic	genetic	JJ
cord-279260-tdvb0fhv	42	15	backgrounds	background	NNS
cord-279260-tdvb0fhv	42	16	including	include	VBG
cord-279260-tdvb0fhv	42	17	outbred	outbred	JJ
cord-279260-tdvb0fhv	42	18	mice	mouse	NNS
cord-279260-tdvb0fhv	42	19	.	.	.
cord-279260-tdvb0fhv	43	1	These	these	DT
cord-279260-tdvb0fhv	43	2	animal	animal	NN
cord-279260-tdvb0fhv	43	3	models	model	NNS
cord-279260-tdvb0fhv	43	4	are	be	VBP
cord-279260-tdvb0fhv	43	5	thus	thus	RB
cord-279260-tdvb0fhv	43	6	suitable	suitable	JJ
cord-279260-tdvb0fhv	43	7	to	to	TO
cord-279260-tdvb0fhv	43	8	evaluate	evaluate	VB
cord-279260-tdvb0fhv	43	9	vaccine	vaccine	NN
cord-279260-tdvb0fhv	43	10	candidates	candidate	NNS
cord-279260-tdvb0fhv	43	11	in	in	IN
cord-279260-tdvb0fhv	43	12	preclinical	preclinical	JJ
cord-279260-tdvb0fhv	43	13	settings	setting	NNS
cord-279260-tdvb0fhv	43	14	.	.	.
cord-279260-tdvb0fhv	44	1	There	there	EX
cord-279260-tdvb0fhv	44	2	is	be	VBZ
cord-279260-tdvb0fhv	44	3	also	also	RB
cord-279260-tdvb0fhv	44	4	a	a	DT
cord-279260-tdvb0fhv	44	5	pressing	press	VBG
cord-279260-tdvb0fhv	44	6	need	need	NN
cord-279260-tdvb0fhv	44	7	to	to	TO
cord-279260-tdvb0fhv	44	8	define	define	VB
cord-279260-tdvb0fhv	44	9	correlates	correlate	NNS
cord-279260-tdvb0fhv	44	10	of	of	IN
cord-279260-tdvb0fhv	44	11	protection	protection	NN
cord-279260-tdvb0fhv	44	12	,	,	,
cord-279260-tdvb0fhv	44	13	which	which	WDT
cord-279260-tdvb0fhv	44	14	have	have	VBP
cord-279260-tdvb0fhv	44	15	the	the	DT
cord-279260-tdvb0fhv	44	16	additional	additional	JJ
cord-279260-tdvb0fhv	44	17	benefit	benefit	NN
cord-279260-tdvb0fhv	44	18	of	of	IN
cord-279260-tdvb0fhv	44	19	serving	serve	VBG
cord-279260-tdvb0fhv	44	20	as	as	IN
cord-279260-tdvb0fhv	44	21	a	a	DT
cord-279260-tdvb0fhv	44	22	benchmark	benchmark	NN
cord-279260-tdvb0fhv	44	23	for	for	IN
cord-279260-tdvb0fhv	44	24	vaccine	vaccine	NN
cord-279260-tdvb0fhv	44	25	evaluation	evaluation	NN
cord-279260-tdvb0fhv	44	26	without	without	IN
cord-279260-tdvb0fhv	44	27	the	the	DT
cord-279260-tdvb0fhv	44	28	need	need	NN
cord-279260-tdvb0fhv	44	29	for	for	IN
cord-279260-tdvb0fhv	44	30	challenge	challenge	NN
cord-279260-tdvb0fhv	44	31	studies	study	NNS
cord-279260-tdvb0fhv	44	32	,	,	,
cord-279260-tdvb0fhv	44	33	an	an	DT
cord-279260-tdvb0fhv	44	34	approach	approach	NN
cord-279260-tdvb0fhv	44	35	that	that	WDT
cord-279260-tdvb0fhv	44	36	has	have	VBZ
cord-279260-tdvb0fhv	44	37	been	be	VBN
cord-279260-tdvb0fhv	44	38	used	use	VBN
cord-279260-tdvb0fhv	44	39	for	for	IN
cord-279260-tdvb0fhv	44	40	many	many	JJ
cord-279260-tdvb0fhv	44	41	different	different	JJ
cord-279260-tdvb0fhv	44	42	pathogens	pathogen	NNS
cord-279260-tdvb0fhv	44	43	[	[	-LRB-
cord-279260-tdvb0fhv	44	44	33	33	CD
cord-279260-tdvb0fhv	44	45	]	]	-RRB-
cord-279260-tdvb0fhv	44	46	.	.	.
cord-279260-tdvb0fhv	45	1	A	a	DT
cord-279260-tdvb0fhv	45	2	typical	typical	JJ
cord-279260-tdvb0fhv	45	3	example	example	NN
cord-279260-tdvb0fhv	45	4	is	be	VBZ
cord-279260-tdvb0fhv	45	5	influenza	influenza	JJ
cord-279260-tdvb0fhv	45	6	vaccine	vaccine	NN
cord-279260-tdvb0fhv	45	7	,	,	,
cord-279260-tdvb0fhv	45	8	where	where	WRB
cord-279260-tdvb0fhv	45	9	a	a	DT
cord-279260-tdvb0fhv	45	10	hemagglutination	hemagglutination	NN
cord-279260-tdvb0fhv	45	11	inhibition	inhibition	NN
cord-279260-tdvb0fhv	45	12	(	(	-LRB-
cord-279260-tdvb0fhv	45	13	HAI	HAI	NNP
cord-279260-tdvb0fhv	45	14	)	)	-RRB-
cord-279260-tdvb0fhv	45	15	titer	titer	NN
cord-279260-tdvb0fhv	45	16	of	of	IN
cord-279260-tdvb0fhv	45	17	≥1:40	≥1:40	NNP
cord-279260-tdvb0fhv	45	18	is	be	VBZ
cord-279260-tdvb0fhv	45	19	a	a	DT
cord-279260-tdvb0fhv	45	20	surrogate	surrogate	NN
cord-279260-tdvb0fhv	45	21	of	of	IN
cord-279260-tdvb0fhv	45	22	protection	protection	NN
cord-279260-tdvb0fhv	45	23	[	[	-LRB-
cord-279260-tdvb0fhv	45	24	34	34	CD
cord-279260-tdvb0fhv	45	25	]	]	-RRB-
cord-279260-tdvb0fhv	45	26	.	.	.
cord-279260-tdvb0fhv	46	1	However	however	RB
cord-279260-tdvb0fhv	46	2	,	,	,
cord-279260-tdvb0fhv	46	3	the	the	DT
cord-279260-tdvb0fhv	46	4	exact	exact	JJ
cord-279260-tdvb0fhv	46	5	serological	serological	JJ
cord-279260-tdvb0fhv	46	6	parameters	parameter	NNS
cord-279260-tdvb0fhv	46	7	that	that	WDT
cord-279260-tdvb0fhv	46	8	provide	provide	VBP
cord-279260-tdvb0fhv	46	9	best	good	JJS
cord-279260-tdvb0fhv	46	10	correlation	correlation	NN
cord-279260-tdvb0fhv	46	11	with	with	IN
cord-279260-tdvb0fhv	46	12	protection	protection	NN
cord-279260-tdvb0fhv	46	13	against	against	IN
cord-279260-tdvb0fhv	46	14	SARS	SARS	NNP
cord-279260-tdvb0fhv	46	15	-	-	HYPH
cord-279260-tdvb0fhv	46	16	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	46	17	infection	infection	NN
cord-279260-tdvb0fhv	46	18	will	will	MD
cord-279260-tdvb0fhv	46	19	need	need	VB
cord-279260-tdvb0fhv	46	20	to	to	TO
cord-279260-tdvb0fhv	46	21	be	be	VB
cord-279260-tdvb0fhv	46	22	investigated	investigate	VBN
cord-279260-tdvb0fhv	46	23	.	.	.
cord-279260-tdvb0fhv	47	1	On	on	IN
cord-279260-tdvb0fhv	47	2	a	a	DT
cord-279260-tdvb0fhv	47	3	related	related	JJ
cord-279260-tdvb0fhv	47	4	note	note	NN
cord-279260-tdvb0fhv	47	5	,	,	,
cord-279260-tdvb0fhv	47	6	evaluating	evaluate	VBG
cord-279260-tdvb0fhv	47	7	the	the	DT
cord-279260-tdvb0fhv	47	8	neutralizing	neutralize	VBG
cord-279260-tdvb0fhv	47	9	antibody	antibody	NN
cord-279260-tdvb0fhv	47	10	titer	titer	NN
cord-279260-tdvb0fhv	47	11	against	against	IN
cord-279260-tdvb0fhv	47	12	This	this	DT
cord-279260-tdvb0fhv	47	13	article	article	NN
cord-279260-tdvb0fhv	47	14	is	be	VBZ
cord-279260-tdvb0fhv	47	15	protected	protect	VBN
cord-279260-tdvb0fhv	47	16	by	by	IN
cord-279260-tdvb0fhv	47	17	copyright	copyright	NN
cord-279260-tdvb0fhv	47	18	.	.	.
cord-279260-tdvb0fhv	48	1	All	all	DT
cord-279260-tdvb0fhv	48	2	rights	right	NNS
cord-279260-tdvb0fhv	48	3	reserved	reserve	VBN
cord-279260-tdvb0fhv	48	4	.	.	.
cord-279260-tdvb0fhv	49	1	Therefore	therefore	RB
cord-279260-tdvb0fhv	49	2	,	,	,
cord-279260-tdvb0fhv	49	3	pseudovirus	pseudovirus	NNP
cord-279260-tdvb0fhv	49	4	assays	assay	NNS
cord-279260-tdvb0fhv	49	5	that	that	WDT
cord-279260-tdvb0fhv	49	6	can	can	MD
cord-279260-tdvb0fhv	49	7	be	be	VB
cord-279260-tdvb0fhv	49	8	performed	perform	VBN
cord-279260-tdvb0fhv	49	9	in	in	IN
cord-279260-tdvb0fhv	49	10	a	a	DT
cord-279260-tdvb0fhv	49	11	BSL2	BSL2	NNP
cord-279260-tdvb0fhv	49	12	setting	setting	NN
cord-279260-tdvb0fhv	49	13	are	be	VBP
cord-279260-tdvb0fhv	49	14	also	also	RB
cord-279260-tdvb0fhv	49	15	valuable	valuable	JJ
cord-279260-tdvb0fhv	49	16	for	for	IN
cord-279260-tdvb0fhv	49	17	vaccine	vaccine	NN
cord-279260-tdvb0fhv	49	18	development	development	NN
cord-279260-tdvb0fhv	49	19	[	[	-LRB-
cord-279260-tdvb0fhv	49	20	35	35	CD
cord-279260-tdvb0fhv	49	21	,	,	,
cord-279260-tdvb0fhv	49	22	36	36	CD
cord-279260-tdvb0fhv	49	23	]	]	-RRB-
cord-279260-tdvb0fhv	49	24	.	.	.
cord-279260-tdvb0fhv	50	1	Zoonotic	Zoonotic	NNP
cord-279260-tdvb0fhv	50	2	coronaviruses	coronaviruse	NNS
cord-279260-tdvb0fhv	50	3	are	be	VBP
cord-279260-tdvb0fhv	50	4	likely	likely	JJ
cord-279260-tdvb0fhv	50	5	to	to	TO
cord-279260-tdvb0fhv	50	6	be	be	VB
cord-279260-tdvb0fhv	50	7	a	a	DT
cord-279260-tdvb0fhv	50	8	continuous	continuous	JJ
cord-279260-tdvb0fhv	50	9	threat	threat	NN
cord-279260-tdvb0fhv	50	10	[	[	-LRB-
cord-279260-tdvb0fhv	50	11	37	37	CD
cord-279260-tdvb0fhv	50	12	]	]	-RRB-
cord-279260-tdvb0fhv	50	13	.	.	.
cord-279260-tdvb0fhv	51	1	Although	although	IN
cord-279260-tdvb0fhv	51	2	generation	generation	NN
cord-279260-tdvb0fhv	51	3	of	of	IN
cord-279260-tdvb0fhv	51	4	a	a	DT
cord-279260-tdvb0fhv	51	5	pan	pan	JJ
cord-279260-tdvb0fhv	51	6	-	-	HYPH
cord-279260-tdvb0fhv	51	7	coronaviruses	coronaviruse	NNS
cord-279260-tdvb0fhv	51	8	vaccine	vaccine	NN
cord-279260-tdvb0fhv	51	9	seems	seem	VBZ
cord-279260-tdvb0fhv	51	10	unlikely	unlikely	JJ
cord-279260-tdvb0fhv	51	11	,	,	,
cord-279260-tdvb0fhv	51	12	owing	owe	VBG
cord-279260-tdvb0fhv	51	13	to	to	IN
cord-279260-tdvb0fhv	51	14	the	the	DT
cord-279260-tdvb0fhv	51	15	high	high	JJ
cord-279260-tdvb0fhv	51	16	genetic	genetic	JJ
cord-279260-tdvb0fhv	51	17	diversity	diversity	NN
cord-279260-tdvb0fhv	51	18	among	among	IN
cord-279260-tdvb0fhv	51	19	different	different	JJ
cord-279260-tdvb0fhv	51	20	genera	genus	NNS
cord-279260-tdvb0fhv	51	21	,	,	,
cord-279260-tdvb0fhv	51	22	it	-PRON-	PRP
cord-279260-tdvb0fhv	51	23	might	may	MD
cord-279260-tdvb0fhv	51	24	be	be	VB
cord-279260-tdvb0fhv	51	25	possible	possible	JJ
cord-279260-tdvb0fhv	51	26	to	to	TO
cord-279260-tdvb0fhv	51	27	develop	develop	VB
cord-279260-tdvb0fhv	51	28	a	a	DT
cord-279260-tdvb0fhv	51	29	pan	pan	JJ
cord-279260-tdvb0fhv	51	30	-	-	JJ
cord-279260-tdvb0fhv	51	31	betacoronavirus	betacoronavirus	JJ
cord-279260-tdvb0fhv	51	32	vaccine	vaccine	NN
cord-279260-tdvb0fhv	51	33	to	to	TO
cord-279260-tdvb0fhv	51	34	prevent	prevent	VB
cord-279260-tdvb0fhv	51	35	the	the	DT
cord-279260-tdvb0fhv	51	36	potential	potential	JJ
cord-279260-tdvb0fhv	51	37	risk	risk	NN
cord-279260-tdvb0fhv	51	38	from	from	IN
cord-279260-tdvb0fhv	51	39	new	new	JJ
cord-279260-tdvb0fhv	51	40	subtypes	subtype	NNS
cord-279260-tdvb0fhv	51	41	identified	identify	VBN
cord-279260-tdvb0fhv	51	42	in	in	IN
cord-279260-tdvb0fhv	51	43	bats	bat	NNS
cord-279260-tdvb0fhv	51	44	,	,	,
cord-279260-tdvb0fhv	51	45	pangolins	pangolin	NNS
cord-279260-tdvb0fhv	51	46	or	or	CC
cord-279260-tdvb0fhv	51	47	other	other	JJ
cord-279260-tdvb0fhv	51	48	species	specie	NNS
cord-279260-tdvb0fhv	51	49	[	[	-LRB-
cord-279260-tdvb0fhv	51	50	37	37	CD
cord-279260-tdvb0fhv	51	51	]	]	-RRB-
cord-279260-tdvb0fhv	51	52	.	.	.
cord-279260-tdvb0fhv	52	1	Indeed	indeed	RB
cord-279260-tdvb0fhv	52	2	,	,	,
cord-279260-tdvb0fhv	52	3	cross	cross	NN
cord-279260-tdvb0fhv	52	4	-	-	NN
cord-279260-tdvb0fhv	52	5	reactivity	reactivity	NN
cord-279260-tdvb0fhv	52	6	between	between	IN
cord-279260-tdvb0fhv	52	7	different	different	JJ
cord-279260-tdvb0fhv	52	8	betacoronaviruses	betacoronaviruse	NNS
cord-279260-tdvb0fhv	52	9	has	have	VBZ
cord-279260-tdvb0fhv	52	10	been	be	VBN
cord-279260-tdvb0fhv	52	11	found	find	VBN
cord-279260-tdvb0fhv	52	12	in	in	IN
cord-279260-tdvb0fhv	52	13	human	human	JJ
cord-279260-tdvb0fhv	52	14	samples	sample	NNS
cord-279260-tdvb0fhv	52	15	.	.	.
cord-279260-tdvb0fhv	53	1	For	for	IN
cord-279260-tdvb0fhv	53	2	example	example	NN
cord-279260-tdvb0fhv	53	3	,	,	,
cord-279260-tdvb0fhv	53	4	a	a	DT
cord-279260-tdvb0fhv	53	5	conserved	conserved	JJ
cord-279260-tdvb0fhv	53	6	CD4	CD4	NNP
cord-279260-tdvb0fhv	53	7	T	T	NNP
cord-279260-tdvb0fhv	53	8	-	-	HYPH
cord-279260-tdvb0fhv	53	9	cell	cell	NN
cord-279260-tdvb0fhv	53	10	epitope	epitope	NN
cord-279260-tdvb0fhv	53	11	can	can	MD
cord-279260-tdvb0fhv	53	12	mediate	mediate	VB
cord-279260-tdvb0fhv	53	13	cross	cross	JJ
cord-279260-tdvb0fhv	53	14	-	-	JJ
cord-279260-tdvb0fhv	53	15	reactive	reactive	JJ
cord-279260-tdvb0fhv	53	16	protection	protection	NN
cord-279260-tdvb0fhv	53	17	between	between	IN
cord-279260-tdvb0fhv	53	18	SARS	SARS	NNP
cord-279260-tdvb0fhv	53	19	-	-	HYPH
cord-279260-tdvb0fhv	53	20	CoV	CoV	NNP
cord-279260-tdvb0fhv	53	21	and	and	CC
cord-279260-tdvb0fhv	53	22	MERS	MERS	NNP
cord-279260-tdvb0fhv	53	23	-	-	HYPH
cord-279260-tdvb0fhv	53	24	CoV	CoV	NNP
cord-279260-tdvb0fhv	53	25	[	[	-LRB-
cord-279260-tdvb0fhv	53	26	38	38	CD
cord-279260-tdvb0fhv	53	27	]	]	-RRB-
cord-279260-tdvb0fhv	53	28	.	.	.
cord-279260-tdvb0fhv	54	1	In	in	IN
cord-279260-tdvb0fhv	54	2	addition	addition	NN
cord-279260-tdvb0fhv	54	3	,	,	,
cord-279260-tdvb0fhv	54	4	our	-PRON-	PRP$
cord-279260-tdvb0fhv	54	5	recent	recent	JJ
cord-279260-tdvb0fhv	54	6	study	study	NN
cord-279260-tdvb0fhv	54	7	has	have	VBZ
cord-279260-tdvb0fhv	54	8	revealed	reveal	VBN
cord-279260-tdvb0fhv	54	9	a	a	DT
cord-279260-tdvb0fhv	54	10	conserved	conserve	VBN
cord-279260-tdvb0fhv	54	11	antibody	antibody	NN
cord-279260-tdvb0fhv	54	12	epitope	epitope	NN
cord-279260-tdvb0fhv	54	13	shared	share	VBN
cord-279260-tdvb0fhv	54	14	by	by	IN
cord-279260-tdvb0fhv	54	15	SARS	SARS	NNP
cord-279260-tdvb0fhv	54	16	-	-	HYPH
cord-279260-tdvb0fhv	54	17	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	54	18	and	and	CC
cord-279260-tdvb0fhv	54	19	SARS	SARS	NNP
cord-279260-tdvb0fhv	54	20	-	-	HYPH
cord-279260-tdvb0fhv	54	21	CoV	CoV	NNP
cord-279260-tdvb0fhv	54	22	[	[	-LRB-
cord-279260-tdvb0fhv	54	23	39	39	CD
cord-279260-tdvb0fhv	54	24	]	]	-RRB-
cord-279260-tdvb0fhv	54	25	.	.	.
cord-279260-tdvb0fhv	55	1	These	these	DT
cord-279260-tdvb0fhv	55	2	results	result	NNS
cord-279260-tdvb0fhv	55	3	indicate	indicate	VBP
cord-279260-tdvb0fhv	55	4	a	a	DT
cord-279260-tdvb0fhv	55	5	potential	potential	JJ
cord-279260-tdvb0fhv	55	6	roadmap	roadmap	NN
cord-279260-tdvb0fhv	55	7	for	for	IN
cord-279260-tdvb0fhv	55	8	the	the	DT
cord-279260-tdvb0fhv	55	9	development	development	NN
cord-279260-tdvb0fhv	55	10	of	of	IN
cord-279260-tdvb0fhv	55	11	universal	universal	JJ
cord-279260-tdvb0fhv	55	12	vaccine	vaccine	NN
cord-279260-tdvb0fhv	55	13	against	against	IN
cord-279260-tdvb0fhv	55	14	coronaviruses	coronaviruse	NNS
cord-279260-tdvb0fhv	55	15	.	.	.
cord-279260-tdvb0fhv	56	1	Although	although	IN
cord-279260-tdvb0fhv	56	2	it	-PRON-	PRP
cord-279260-tdvb0fhv	56	3	is	be	VBZ
cord-279260-tdvb0fhv	56	4	not	not	RB
cord-279260-tdvb0fhv	56	5	possible	possible	JJ
cord-279260-tdvb0fhv	56	6	to	to	TO
cord-279260-tdvb0fhv	56	7	predict	predict	VB
cord-279260-tdvb0fhv	56	8	,	,	,
cord-279260-tdvb0fhv	56	9	at	at	IN
cord-279260-tdvb0fhv	56	10	this	this	DT
cord-279260-tdvb0fhv	56	11	moment	moment	NN
cord-279260-tdvb0fhv	56	12	,	,	,
cord-279260-tdvb0fhv	56	13	the	the	DT
cord-279260-tdvb0fhv	56	14	strain	strain	NN
cord-279260-tdvb0fhv	56	15	of	of	IN
cord-279260-tdvb0fhv	56	16	the	the	DT
cord-279260-tdvb0fhv	56	17	next	next	JJ
cord-279260-tdvb0fhv	56	18	coronavirus	coronavirus	NN
cord-279260-tdvb0fhv	56	19	that	that	WDT
cord-279260-tdvb0fhv	56	20	will	will	MD
cord-279260-tdvb0fhv	56	21	jump	jump	VB
cord-279260-tdvb0fhv	56	22	species	specie	NNS
cord-279260-tdvb0fhv	56	23	,	,	,
cord-279260-tdvb0fhv	56	24	continuing	continue	VBG
cord-279260-tdvb0fhv	56	25	exploration	exploration	NN
cord-279260-tdvb0fhv	56	26	of	of	IN
cord-279260-tdvb0fhv	56	27	the	the	DT
cord-279260-tdvb0fhv	56	28	B	b	NN
cord-279260-tdvb0fhv	56	29	-	-	HYPH
cord-279260-tdvb0fhv	56	30	cell	cell	NN
cord-279260-tdvb0fhv	56	31	repertoire	repertoire	NN
cord-279260-tdvb0fhv	56	32	to	to	TO
cord-279260-tdvb0fhv	56	33	identify	identify	VB
cord-279260-tdvb0fhv	56	34	cross	cross	JJ
cord-279260-tdvb0fhv	56	35	-	-	JJ
cord-279260-tdvb0fhv	56	36	reactive	reactive	JJ
cord-279260-tdvb0fhv	56	37	epitopes	epitope	NNS
cord-279260-tdvb0fhv	56	38	will	will	MD
cord-279260-tdvb0fhv	56	39	be	be	VB
cord-279260-tdvb0fhv	56	40	important	important	JJ
cord-279260-tdvb0fhv	56	41	for	for	IN
cord-279260-tdvb0fhv	56	42	the	the	DT
cord-279260-tdvb0fhv	56	43	development	development	NN
cord-279260-tdvb0fhv	56	44	of	of	IN
cord-279260-tdvb0fhv	56	45	a	a	DT
cord-279260-tdvb0fhv	56	46	coronavirus	coronavirus	NN
cord-279260-tdvb0fhv	56	47	vaccine	vaccine	NN
cord-279260-tdvb0fhv	56	48	with	with	IN
cord-279260-tdvb0fhv	56	49	high	high	JJ
cord-279260-tdvb0fhv	56	50	breadth	breadth	NN
cord-279260-tdvb0fhv	56	51	of	of	IN
cord-279260-tdvb0fhv	56	52	coverage	coverage	NN
cord-279260-tdvb0fhv	56	53	.	.	.
cord-279260-tdvb0fhv	57	1	Taken	take	VBN
cord-279260-tdvb0fhv	57	2	together	together	RB
cord-279260-tdvb0fhv	57	3	,	,	,
cord-279260-tdvb0fhv	57	4	while	while	IN
cord-279260-tdvb0fhv	57	5	therapeutic	therapeutic	JJ
cord-279260-tdvb0fhv	57	6	approaches	approach	NNS
cord-279260-tdvb0fhv	57	7	for	for	IN
cord-279260-tdvb0fhv	57	8	COVID-19	COVID-19	NNP
cord-279260-tdvb0fhv	57	9	are	be	VBP
cord-279260-tdvb0fhv	57	10	urgently	urgently	RB
cord-279260-tdvb0fhv	57	11	needed	need	VBN
cord-279260-tdvb0fhv	57	12	(	(	-LRB-
cord-279260-tdvb0fhv	57	13	reviewed	review	VBN
cord-279260-tdvb0fhv	57	14	in	in	IN
cord-279260-tdvb0fhv	57	15	[	[	-LRB-
cord-279260-tdvb0fhv	57	16	40	40	CD
cord-279260-tdvb0fhv	57	17	]	]	-RRB-
cord-279260-tdvb0fhv	57	18	)	)	-RRB-
cord-279260-tdvb0fhv	58	1	given	give	VBN
cord-279260-tdvb0fhv	58	2	the	the	DT
cord-279260-tdvb0fhv	58	3	increasing	increase	VBG
cord-279260-tdvb0fhv	58	4	number	number	NN
cord-279260-tdvb0fhv	58	5	of	of	IN
cord-279260-tdvb0fhv	58	6	active	active	JJ
cord-279260-tdvb0fhv	58	7	cases	case	NNS
cord-279260-tdvb0fhv	58	8	,	,	,
cord-279260-tdvb0fhv	58	9	the	the	DT
cord-279260-tdvb0fhv	58	10	ultimate	ultimate	JJ
cord-279260-tdvb0fhv	58	11	goal	goal	NN
cord-279260-tdvb0fhv	58	12	of	of	IN
cord-279260-tdvb0fhv	58	13	establishing	establish	VBG
cord-279260-tdvb0fhv	58	14	sterilizing	sterilize	VBG
cord-279260-tdvb0fhv	58	15	immunity	immunity	NN
cord-279260-tdvb0fhv	58	16	in	in	IN
cord-279260-tdvb0fhv	58	17	This	this	DT
cord-279260-tdvb0fhv	58	18	article	article	NN
cord-279260-tdvb0fhv	58	19	is	be	VBZ
cord-279260-tdvb0fhv	58	20	protected	protect	VBN
cord-279260-tdvb0fhv	58	21	by	by	IN
cord-279260-tdvb0fhv	58	22	copyright	copyright	NN
cord-279260-tdvb0fhv	58	23	.	.	.
cord-279260-tdvb0fhv	59	1	All	all	DT
cord-279260-tdvb0fhv	59	2	rights	right	NNS
cord-279260-tdvb0fhv	59	3	reserved	reserve	VBN
cord-279260-tdvb0fhv	59	4	.	.	.
cord-279260-tdvb0fhv	60	1	uninfected	uninfected	JJ
cord-279260-tdvb0fhv	60	2	individuals	individual	NNS
cord-279260-tdvb0fhv	60	3	will	will	MD
cord-279260-tdvb0fhv	60	4	require	require	VB
cord-279260-tdvb0fhv	60	5	an	an	DT
cord-279260-tdvb0fhv	60	6	SARS	SARS	NNP
cord-279260-tdvb0fhv	60	7	-	-	HYPH
cord-279260-tdvb0fhv	60	8	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	60	9	vaccine	vaccine	NN
cord-279260-tdvb0fhv	60	10	.	.	.
cord-279260-tdvb0fhv	61	1	We	-PRON-	PRP
cord-279260-tdvb0fhv	61	2	are	be	VBP
cord-279260-tdvb0fhv	61	3	confident	confident	JJ
cord-279260-tdvb0fhv	61	4	that	that	IN
cord-279260-tdvb0fhv	61	5	the	the	DT
cord-279260-tdvb0fhv	61	6	rapid	rapid	JJ
cord-279260-tdvb0fhv	61	7	and	and	CC
cord-279260-tdvb0fhv	61	8	collaborative	collaborative	JJ
cord-279260-tdvb0fhv	61	9	efforts	effort	NNS
cord-279260-tdvb0fhv	61	10	among	among	IN
cord-279260-tdvb0fhv	61	11	researchers	researcher	NNS
cord-279260-tdvb0fhv	61	12	around	around	IN
cord-279260-tdvb0fhv	61	13	the	the	DT
cord-279260-tdvb0fhv	61	14	globe	globe	NN
cord-279260-tdvb0fhv	61	15	will	will	MD
cord-279260-tdvb0fhv	61	16	offer	offer	VB
cord-279260-tdvb0fhv	61	17	an	an	DT
cord-279260-tdvb0fhv	61	18	effective	effective	JJ
cord-279260-tdvb0fhv	61	19	countermeasure	countermeasure	NN
cord-279260-tdvb0fhv	61	20	to	to	TO
cord-279260-tdvb0fhv	61	21	COVID-19	covid-19	VB
cord-279260-tdvb0fhv	61	22	in	in	IN
cord-279260-tdvb0fhv	61	23	the	the	DT
cord-279260-tdvb0fhv	61	24	near	near	JJ
cord-279260-tdvb0fhv	61	25	future	future	NN
cord-279260-tdvb0fhv	61	26	.	.	.
cord-279260-tdvb0fhv	62	1	The	the	DT
cord-279260-tdvb0fhv	62	2	SARS	SARS	NNP
cord-279260-tdvb0fhv	62	3	-	-	HYPH
cord-279260-tdvb0fhv	62	4	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	62	5	receptor	receptor	NN
cord-279260-tdvb0fhv	62	6	-	-	HYPH
cord-279260-tdvb0fhv	62	7	binding	bind	VBG
cord-279260-tdvb0fhv	62	8	domain	domain	NN
cord-279260-tdvb0fhv	62	9	elicits	elicit	VBZ
cord-279260-tdvb0fhv	62	10	a	a	DT
cord-279260-tdvb0fhv	62	11	potent	potent	JJ
cord-279260-tdvb0fhv	62	12	neutralizing	neutralize	VBG
cord-279260-tdvb0fhv	62	13	response	response	NN
cord-279260-tdvb0fhv	62	14	without	without	IN
cord-279260-tdvb0fhv	62	15	antibody	antibody	NN
cord-279260-tdvb0fhv	62	16	-	-	HYPH
cord-279260-tdvb0fhv	62	17	dependent	dependent	JJ
cord-279260-tdvb0fhv	62	18	enhancement	enhancement	NN
cord-279260-tdvb0fhv	62	19	Vaccine	vaccine	NN
cord-279260-tdvb0fhv	62	20	adjuvants	adjuvant	NNS
cord-279260-tdvb0fhv	62	21	:	:	:
cord-279260-tdvb0fhv	62	22	putting	put	VBG
cord-279260-tdvb0fhv	62	23	innate	innate	JJ
cord-279260-tdvb0fhv	62	24	immunity	immunity	NN
cord-279260-tdvb0fhv	62	25	to	to	TO
cord-279260-tdvb0fhv	62	26	work	work	VB
cord-279260-tdvb0fhv	62	27	Different	different	JJ
cord-279260-tdvb0fhv	62	28	human	human	JJ
cord-279260-tdvb0fhv	62	29	vaccine	vaccine	NN
cord-279260-tdvb0fhv	62	30	adjuvants	adjuvant	NNS
cord-279260-tdvb0fhv	62	31	promote	promote	VBP
cord-279260-tdvb0fhv	62	32	distinct	distinct	JJ
cord-279260-tdvb0fhv	62	33	antigen	antigen	NN
cord-279260-tdvb0fhv	62	34	-	-	HYPH
cord-279260-tdvb0fhv	62	35	independent	independent	JJ
cord-279260-tdvb0fhv	62	36	immunological	immunological	JJ
cord-279260-tdvb0fhv	62	37	signatures	signature	NNS
cord-279260-tdvb0fhv	62	38	tailored	tailor	VBN
cord-279260-tdvb0fhv	62	39	to	to	IN
cord-279260-tdvb0fhv	62	40	different	different	JJ
cord-279260-tdvb0fhv	62	41	pathogens	pathogen	NNS
cord-279260-tdvb0fhv	62	42	Evolution	evolution	NN
cord-279260-tdvb0fhv	62	43	of	of	IN
cord-279260-tdvb0fhv	62	44	the	the	DT
cord-279260-tdvb0fhv	62	45	immune	immune	JJ
cord-279260-tdvb0fhv	62	46	system	system	NN
cord-279260-tdvb0fhv	62	47	in	in	IN
cord-279260-tdvb0fhv	62	48	humans	human	NNS
cord-279260-tdvb0fhv	62	49	from	from	IN
cord-279260-tdvb0fhv	62	50	infancy	infancy	NN
cord-279260-tdvb0fhv	62	51	to	to	IN
cord-279260-tdvb0fhv	62	52	old	old	JJ
cord-279260-tdvb0fhv	62	53	age	age	NN
cord-279260-tdvb0fhv	62	54	Comparative	comparative	JJ
cord-279260-tdvb0fhv	62	55	pathogenesis	pathogenesis	NN
cord-279260-tdvb0fhv	62	56	of	of	IN
cord-279260-tdvb0fhv	62	57	COVID-19	COVID-19	NNP
cord-279260-tdvb0fhv	62	58	,	,	,
cord-279260-tdvb0fhv	62	59	MERS	MERS	NNP
cord-279260-tdvb0fhv	62	60	and	and	CC
cord-279260-tdvb0fhv	62	61	SARS	SARS	NNP
cord-279260-tdvb0fhv	62	62	in	in	IN
cord-279260-tdvb0fhv	62	63	a	a	DT
cord-279260-tdvb0fhv	62	64	nonhuman	nonhuman	NN
cord-279260-tdvb0fhv	62	65	primate	primate	NN
cord-279260-tdvb0fhv	62	66	model	model	NN
cord-279260-tdvb0fhv	62	67	Simulation	Simulation	NNP
cord-279260-tdvb0fhv	62	68	of	of	IN
cord-279260-tdvb0fhv	62	69	the	the	DT
cord-279260-tdvb0fhv	62	70	clinical	clinical	JJ
cord-279260-tdvb0fhv	62	71	and	and	CC
cord-279260-tdvb0fhv	62	72	pathological	pathological	JJ
cord-279260-tdvb0fhv	62	73	manifestations	manifestation	NNS
cord-279260-tdvb0fhv	62	74	of	of	IN
cord-279260-tdvb0fhv	62	75	Coronavirus	Coronavirus	NNP
cord-279260-tdvb0fhv	62	76	Disease	Disease	NNP
cord-279260-tdvb0fhv	62	77	2019	2019	CD
cord-279260-tdvb0fhv	62	78	(	(	-LRB-
cord-279260-tdvb0fhv	62	79	COVID-19	COVID-19	NNP
cord-279260-tdvb0fhv	62	80	)	)	-RRB-
cord-279260-tdvb0fhv	62	81	in	in	IN
cord-279260-tdvb0fhv	62	82	golden	golden	JJ
cord-279260-tdvb0fhv	62	83	Syrian	syrian	JJ
cord-279260-tdvb0fhv	62	84	hamster	hamster	NN
cord-279260-tdvb0fhv	62	85	model	model	NN
cord-279260-tdvb0fhv	62	86	:	:	:
cord-279260-tdvb0fhv	62	87	implications	implication	NNS
cord-279260-tdvb0fhv	62	88	for	for	IN
cord-279260-tdvb0fhv	62	89	disease	disease	NN
cord-279260-tdvb0fhv	62	90	pathogenesis	pathogenesis	NN
cord-279260-tdvb0fhv	62	91	and	and	CC
cord-279260-tdvb0fhv	62	92	transmissibility	transmissibility	NN
cord-279260-tdvb0fhv	62	93	Infection	infection	NN
cord-279260-tdvb0fhv	62	94	and	and	CC
cord-279260-tdvb0fhv	62	95	rapid	rapid	JJ
cord-279260-tdvb0fhv	62	96	transmission	transmission	NN
cord-279260-tdvb0fhv	62	97	of	of	IN
cord-279260-tdvb0fhv	62	98	SARS	SARS	NNP
cord-279260-tdvb0fhv	62	99	-	-	HYPH
cord-279260-tdvb0fhv	62	100	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	62	101	in	in	IN
cord-279260-tdvb0fhv	62	102	ferrets	ferret	NNS
cord-279260-tdvb0fhv	62	103	Lethal	lethal	JJ
cord-279260-tdvb0fhv	62	104	infection	infection	NN
cord-279260-tdvb0fhv	62	105	of	of	IN
cord-279260-tdvb0fhv	62	106	K18-hACE2	k18-hace2	JJ
cord-279260-tdvb0fhv	62	107	mice	mouse	NNS
cord-279260-tdvb0fhv	62	108	infected	infect	VBN
cord-279260-tdvb0fhv	62	109	with	with	IN
cord-279260-tdvb0fhv	62	110	severe	severe	JJ
cord-279260-tdvb0fhv	62	111	acute	acute	JJ
cord-279260-tdvb0fhv	62	112	respiratory	respiratory	JJ
cord-279260-tdvb0fhv	62	113	syndrome	syndrome	NN
cord-279260-tdvb0fhv	62	114	coronavirus	coronavirus	NN
cord-279260-tdvb0fhv	63	1	The	the	DT
cord-279260-tdvb0fhv	63	2	pathogenicity	pathogenicity	NN
cord-279260-tdvb0fhv	63	3	of	of	IN
cord-279260-tdvb0fhv	63	4	SARS	SARS	NNP
cord-279260-tdvb0fhv	63	5	-	-	HYPH
cord-279260-tdvb0fhv	63	6	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	63	7	in	in	IN
cord-279260-tdvb0fhv	63	8	hACE2	hace2	NN
cord-279260-tdvb0fhv	63	9	transgenic	transgenic	JJ
cord-279260-tdvb0fhv	63	10	mice	mouse	NNS
cord-279260-tdvb0fhv	63	11	Rapid	rapid	JJ
cord-279260-tdvb0fhv	63	12	generation	generation	NN
cord-279260-tdvb0fhv	63	13	of	of	IN
cord-279260-tdvb0fhv	63	14	a	a	DT
cord-279260-tdvb0fhv	63	15	mouse	mouse	NN
cord-279260-tdvb0fhv	63	16	model	model	NN
cord-279260-tdvb0fhv	63	17	for	for	IN
cord-279260-tdvb0fhv	63	18	Middle	Middle	NNP
cord-279260-tdvb0fhv	63	19	East	East	NNP
cord-279260-tdvb0fhv	63	20	respiratory	respiratory	JJ
cord-279260-tdvb0fhv	63	21	syndrome	syndrome	NN
cord-279260-tdvb0fhv	63	22	Correlates	correlate	NNS
cord-279260-tdvb0fhv	63	23	of	of	IN
cord-279260-tdvb0fhv	63	24	protection	protection	NN
cord-279260-tdvb0fhv	63	25	induced	induce	VBN
cord-279260-tdvb0fhv	63	26	by	by	IN
cord-279260-tdvb0fhv	63	27	vaccination	vaccination	NN
cord-279260-tdvb0fhv	63	28	Correlates	correlate	NNS
cord-279260-tdvb0fhv	63	29	of	of	IN
cord-279260-tdvb0fhv	63	30	protection	protection	NN
cord-279260-tdvb0fhv	63	31	to	to	IN
cord-279260-tdvb0fhv	63	32	influenza	influenza	NN
cord-279260-tdvb0fhv	63	33	virus	virus	NN
cord-279260-tdvb0fhv	63	34	,	,	,
cord-279260-tdvb0fhv	63	35	where	where	WRB
cord-279260-tdvb0fhv	63	36	do	do	VBP
cord-279260-tdvb0fhv	63	37	we	-PRON-	PRP
cord-279260-tdvb0fhv	63	38	go	go	VB
cord-279260-tdvb0fhv	63	39	from	from	IN
cord-279260-tdvb0fhv	63	40	here	here	RB
cord-279260-tdvb0fhv	63	41	?	?	.
cord-279260-tdvb0fhv	64	1	Characterization	characterization	NN
cord-279260-tdvb0fhv	64	2	of	of	IN
cord-279260-tdvb0fhv	64	3	spike	spike	NN
cord-279260-tdvb0fhv	64	4	glycoprotein	glycoprotein	NN
cord-279260-tdvb0fhv	64	5	of	of	IN
cord-279260-tdvb0fhv	64	6	SARS	SARS	NNP
cord-279260-tdvb0fhv	64	7	-	-	HYPH
cord-279260-tdvb0fhv	64	8	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	64	9	on	on	IN
cord-279260-tdvb0fhv	64	10	virus	virus	NN
cord-279260-tdvb0fhv	64	11	entry	entry	NN
cord-279260-tdvb0fhv	64	12	and	and	CC
cord-279260-tdvb0fhv	64	13	its	-PRON-	PRP$
cord-279260-tdvb0fhv	64	14	immune	immune	JJ
cord-279260-tdvb0fhv	64	15	cross	cross	NN
cord-279260-tdvb0fhv	64	16	-	-	NN
cord-279260-tdvb0fhv	64	17	reactivity	reactivity	NN
cord-279260-tdvb0fhv	64	18	with	with	IN
cord-279260-tdvb0fhv	64	19	SARS	SARS	NNP
cord-279260-tdvb0fhv	64	20	-	-	HYPH
cord-279260-tdvb0fhv	64	21	CoV	CoV	NNP
cord-279260-tdvb0fhv	64	22	Establishment	Establishment	NNP
cord-279260-tdvb0fhv	65	1	This	this	DT
cord-279260-tdvb0fhv	65	2	article	article	NN
cord-279260-tdvb0fhv	65	3	is	be	VBZ
cord-279260-tdvb0fhv	65	4	protected	protect	VBN
cord-279260-tdvb0fhv	65	5	by	by	IN
cord-279260-tdvb0fhv	65	6	copyright	copyright	NN
cord-279260-tdvb0fhv	65	7	.	.	.
cord-279260-tdvb0fhv	66	1	All	all	DT
cord-279260-tdvb0fhv	66	2	rights	right	NNS
cord-279260-tdvb0fhv	66	3	reserved	reserve	VBN
cord-279260-tdvb0fhv	66	4	.	.	.
cord-279260-tdvb0fhv	67	1	and	and	CC
cord-279260-tdvb0fhv	67	2	validation	validation	NN
cord-279260-tdvb0fhv	67	3	of	of	IN
cord-279260-tdvb0fhv	67	4	a	a	DT
cord-279260-tdvb0fhv	67	5	pseudovirus	pseudovirus	JJ
cord-279260-tdvb0fhv	67	6	neutralization	neutralization	NN
cord-279260-tdvb0fhv	67	7	assay	assay	NN
cord-279260-tdvb0fhv	67	8	for	for	IN
cord-279260-tdvb0fhv	67	9	SARS	SARS	NNP
cord-279260-tdvb0fhv	67	10	-	-	HYPH
cord-279260-tdvb0fhv	67	11	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	68	1	A	a	DT
cord-279260-tdvb0fhv	68	2	SARS	SARS	NNP
cord-279260-tdvb0fhv	68	3	-	-	HYPH
cord-279260-tdvb0fhv	68	4	like	like	JJ
cord-279260-tdvb0fhv	68	5	cluster	cluster	NN
cord-279260-tdvb0fhv	68	6	of	of	IN
cord-279260-tdvb0fhv	68	7	circulating	circulate	VBG
cord-279260-tdvb0fhv	68	8	bat	bat	NN
cord-279260-tdvb0fhv	68	9	coronaviruses	coronaviruse	NNS
cord-279260-tdvb0fhv	68	10	shows	show	VBZ
cord-279260-tdvb0fhv	68	11	potential	potential	NN
cord-279260-tdvb0fhv	68	12	for	for	IN
cord-279260-tdvb0fhv	68	13	human	human	JJ
cord-279260-tdvb0fhv	68	14	emergence	emergence	NN
cord-279260-tdvb0fhv	68	15	Cells	cell	NNS
cord-279260-tdvb0fhv	68	16	Mediate	mediate	VBP
cord-279260-tdvb0fhv	68	17	Protective	protective	JJ
cord-279260-tdvb0fhv	68	18	Immunity	immunity	NN
cord-279260-tdvb0fhv	68	19	against	against	IN
cord-279260-tdvb0fhv	68	20	Emerging	Emerging	NNP
cord-279260-tdvb0fhv	68	21	Respiratory	Respiratory	NNP
cord-279260-tdvb0fhv	68	22	Coronaviruses	Coronaviruses	NNPS
cord-279260-tdvb0fhv	68	23	.	.	.
cord-279260-tdvb0fhv	69	1	Immunity	immunity	NN
cord-279260-tdvb0fhv	69	2	A	a	DT
cord-279260-tdvb0fhv	69	3	highly	highly	RB
cord-279260-tdvb0fhv	69	4	conserved	conserved	JJ
cord-279260-tdvb0fhv	69	5	cryptic	cryptic	JJ
cord-279260-tdvb0fhv	69	6	epitope	epitope	NN
cord-279260-tdvb0fhv	69	7	in	in	IN
cord-279260-tdvb0fhv	69	8	the	the	DT
cord-279260-tdvb0fhv	69	9	receptor	receptor	NN
cord-279260-tdvb0fhv	69	10	-	-	HYPH
cord-279260-tdvb0fhv	69	11	binding	bind	VBG
cord-279260-tdvb0fhv	69	12	domains	domain	NNS
cord-279260-tdvb0fhv	69	13	of	of	IN
cord-279260-tdvb0fhv	69	14	SARS	SARS	NNP
cord-279260-tdvb0fhv	69	15	-	-	HYPH
cord-279260-tdvb0fhv	69	16	CoV-2	CoV-2	NNP
cord-279260-tdvb0fhv	69	17	and	and	CC
cord-279260-tdvb0fhv	69	18	SARS	SARS	NNP
cord-279260-tdvb0fhv	69	19	-	-	HYPH
cord-279260-tdvb0fhv	69	20	CoV	CoV	NNP
cord-279260-tdvb0fhv	69	21	Controlled	control	VBN
cord-279260-tdvb0fhv	69	22	modulation	modulation	NN
cord-279260-tdvb0fhv	69	23	of	of	IN
cord-279260-tdvb0fhv	69	24	innate	innate	JJ
cord-279260-tdvb0fhv	69	25	immunity	immunity	NN
cord-279260-tdvb0fhv	69	26	to	to	TO
cord-279260-tdvb0fhv	69	27	prevent	prevent	VB
cord-279260-tdvb0fhv	69	28	and	and	CC
cord-279260-tdvb0fhv	69	29	treat	treat	VB
cord-279260-tdvb0fhv	69	30	COVID-19	COVID-19	NNP
cord-279260-tdvb0fhv	69	31	disease	disease	NN
cord-279260-tdvb0fhv	70	1	We	-PRON-	PRP
cord-279260-tdvb0fhv	70	2	thank	thank	VBP
cord-279260-tdvb0fhv	70	3	Profs	Profs	NNP
cord-279260-tdvb0fhv	70	4	Roberto	Roberto	NNP
cord-279260-tdvb0fhv	70	5	Bruzzone	Bruzzone	NNP
cord-279260-tdvb0fhv	70	6	and	and	CC
cord-279260-tdvb0fhv	70	7	Stanley	Stanley	NNP
cord-279260-tdvb0fhv	70	8	Perlman	Perlman	NNP
cord-279260-tdvb0fhv	70	9	for	for	IN
cord-279260-tdvb0fhv	70	10	helpful	helpful	JJ
cord-279260-tdvb0fhv	70	11	discussions	discussion	NNS
cord-279260-tdvb0fhv	70	12	.	.	.
cord-279260-tdvb0fhv	70	13	 	 	_SP
cord-279260-tdvb0fhv	71	1	The	the	DT
cord-279260-tdvb0fhv	71	2	authors	author	NNS
cord-279260-tdvb0fhv	71	3	declare	declare	VBP
cord-279260-tdvb0fhv	71	4	no	no	DT
cord-279260-tdvb0fhv	71	5	financial	financial	JJ
cord-279260-tdvb0fhv	71	6	or	or	CC
cord-279260-tdvb0fhv	71	7	commercial	commercial	JJ
cord-279260-tdvb0fhv	71	8	conflict	conflict	NN
cord-279260-tdvb0fhv	71	9	of	of	IN
cord-279260-tdvb0fhv	71	10	interest	interest	NN
cord-279260-tdvb0fhv	71	11	.	.	.
cord-279260-tdvb0fhv	72	1	This	this	DT
cord-279260-tdvb0fhv	72	2	article	article	NN
cord-279260-tdvb0fhv	72	3	is	be	VBZ
cord-279260-tdvb0fhv	72	4	protected	protect	VBN
cord-279260-tdvb0fhv	72	5	by	by	IN
cord-279260-tdvb0fhv	72	6	copyright	copyright	NN
cord-279260-tdvb0fhv	72	7	.	.	.
cord-279260-tdvb0fhv	73	1	All	all	DT
cord-279260-tdvb0fhv	73	2	rights	right	NNS
cord-279260-tdvb0fhv	73	3	reserved	reserve	VBN
cord-279260-tdvb0fhv	73	4	.	.	.
cord-279260-tdvb0fhv	74	1	This	this	DT
cord-279260-tdvb0fhv	74	2	article	article	NN
cord-279260-tdvb0fhv	74	3	is	be	VBZ
cord-279260-tdvb0fhv	74	4	protected	protect	VBN
cord-279260-tdvb0fhv	74	5	by	by	IN
cord-279260-tdvb0fhv	74	6	copyright	copyright	NN
cord-279260-tdvb0fhv	74	7	.	.	.
cord-279260-tdvb0fhv	75	1	All	all	DT
cord-279260-tdvb0fhv	75	2	rights	right	NNS
cord-279260-tdvb0fhv	75	3	reserved	reserve	VBN
cord-279260-tdvb0fhv	75	4	.	.	.
cord-279260-tdvb0fhv	76	1	An	an	DT
cord-279260-tdvb0fhv	76	2	ideal	ideal	JJ
cord-279260-tdvb0fhv	76	3	COVID-19	covid-19	JJ
cord-279260-tdvb0fhv	76	4	vaccine	vaccine	NN
cord-279260-tdvb0fhv	76	5	should	should	MD
cord-279260-tdvb0fhv	76	6	offer	offer	VB
cord-279260-tdvb0fhv	76	7	long	long	JJ
cord-279260-tdvb0fhv	76	8	-	-	HYPH
cord-279260-tdvb0fhv	76	9	term	term	NN
cord-279260-tdvb0fhv	76	10	protection	protection	NN
cord-279260-tdvb0fhv	76	11	with	with	IN
cord-279260-tdvb0fhv	76	12	no	no	DT
cord-279260-tdvb0fhv	76	13	adverse	adverse	JJ
cord-279260-tdvb0fhv	76	14	effect	effect	NN
cord-279260-tdvb0fhv	76	15	.	.	.
cord-279260-tdvb0fhv	77	1	The	the	DT
cord-279260-tdvb0fhv	77	2	current	current	JJ
cord-279260-tdvb0fhv	77	3	status	status	NN
cord-279260-tdvb0fhv	77	4	of	of	IN
cord-279260-tdvb0fhv	77	5	COVID-19	covid-19	JJ
cord-279260-tdvb0fhv	77	6	vaccine	vaccine	NN
cord-279260-tdvb0fhv	77	7	development	development	NN
cord-279260-tdvb0fhv	77	8	and	and	CC
cord-279260-tdvb0fhv	77	9	factors	factor	NNS
cord-279260-tdvb0fhv	77	10	that	that	WDT
cord-279260-tdvb0fhv	77	11	need	need	VBP
cord-279260-tdvb0fhv	77	12	to	to	TO
cord-279260-tdvb0fhv	77	13	be	be	VB
cord-279260-tdvb0fhv	77	14	considered	consider	VBN
cord-279260-tdvb0fhv	77	15	are	be	VBP
cord-279260-tdvb0fhv	77	16	discussed	discuss	VBN
cord-279260-tdvb0fhv	77	17	.	.	.