id author title date pages extension mime words sentences flesch summary cache txt cord-279026-s3yx62u6 Tizard, Ian R. Adverse consequences of vaccination 2020-07-10 .txt text/plain 6722 432 46 Adverse events associated with vaccination that might compromise the health of an animal are usually rare, mild, and transient. Traditionally, adverse events resulting from vaccine administration have been reported by veterinarians to manufacturers or government agencies. It has, however, proved possible by examining the electronic medical records of a very large small animal general practice, to determine the prevalence of vaccine-associated adverse events in over a million dogs. The use of a standardized reporting system within a very large population has permitted objective analysis of the prevalence of adverse events occurring within three days of vaccine administration. Out of 1,226,159 dogs receiving 3,439,576 vaccine doses, 4678 adverse events were recorded (38.2/10,000 dogs); 72.8% of these events occurred on the same day the vaccine was administered, 31.7% were considered to be allergic reactions, 1.7% were classified as anaphylaxis, and 65.8% were considered "vaccine reactions" and were likely caused by innate immune responses. ./cache/cord-279026-s3yx62u6.txt ./txt/cord-279026-s3yx62u6.txt