id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-269448-1jikrn37	Borja-Cabrera, G.P.	Immunogenicity assay of the Leishmune(®) vaccine against canine visceral leishmaniasis in Brazil	2008-09-15		.txt	text/plain	4941	231	45	The strong immunogenicity induced by Leishmune(®) vaccine was demonstrated by the 98% of FML-seroconversion, increase in absorbencies, the 82.7% DTH positive reactions and increase in skin test size diameters, the average increase in CD8+ total lymphocytes population in blood (27.1%), expected for QS21 saponin-containing vaccine, the sustained proportions of CD4+ T cells, and the average increased proportions of CD21+ B lymphocytes (42.3%). Six hundred healthy dogs from the canine visceral leishmaniasis endemic towns of Araç atuba, Andradina, Valparaíso, Guararapes, Bauru (São Paulo state) and Belo Horizonte, Nova Lima, Sete Lagoas (Minas Gerais state), Brazil, showing previous negative results in Leishmania-serology by the immunofluorescent assay [33] were selected for vaccination with three doses of Leishmune ® (Fort Dodge Animal Health, Campinas, SP, Brazil), in a 21-day interval, through the subcutaneous (sc) route [32] and a booster in month 12.	./cache/cord-269448-1jikrn37.txt	./txt/cord-269448-1jikrn37.txt