id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-267666-i7uuf3ck	Sarkar, Bishajit	Engineering a Novel Subunit Vaccine against SARS-CoV-2 by Exploring Immunoformatics Approach	2020-11-11		.txt	text/plain	1873	129	50	Therefore, in this study, immunoinformatics methods were exploited to design a novel epitope-based subunit vaccine against the SARS-CoV-2, targeting four essential proteins of the virus i.e., spike glycoprotein, nucleocapsid phosphoprotein, membrane glycoprotein, and envelope protein. Thereafter, several in silico validations i.e., the molecular docking, molecular dynamics simulation (including the RMSF and RMSD studies), and immune simulation studies were also performed which predicted that the designed vaccine should be quite safe, effective, and stable within the biological environment. The MHC class-I and class-II epitopes were predicted from the target protein sequences for 503 constructing the vaccine. Exploring Leishmania secretory proteins 1232 to design B and T cell multi-epitope subunit vaccine using immunoinformatics approach Immunoinformatics approaches 1236 to explore Helicobacter Pylori proteome (Virulence Factors) to design B and T cell multi-epitope 1237 subunit vaccine. Immunoinformatics-guided designing of 1405 epitope-based subunit vaccine against the SARS Coronavirus-2 (SARS-CoV-2)	./cache/cord-267666-i7uuf3ck.txt	./txt/cord-267666-i7uuf3ck.txt