id author title date pages extension mime words sentences flesch summary cache txt cord-005400-50lmj4op Ada, Gordon Overview of vaccines and vaccination 2005 .txt text/plain 7479 386 50 Of the 80-plus known infectious agents pathogenic for humans, there are now more than 30 vaccines against 26 mainly viral and bacterial infections and these greatly minimize subsequent disease and prevent death after exposure to those agents. Vaccines are designed as a prophylactic measure to induce a lasting immune response so that on subsequent exposure to the particular infectious agent, the extent of infection is reduced to such an extent that disease does not occur (1). More recently, the use of avipox viruses such as fowlpox and canarypox, which undergo an abortive infection in humans, is being used in humans as vectors of DNA coding for antigens of other infectious agents for which vaccines are not yet available (2). Live, attenuated agent vaccines have the potential to stimulate strong humoral and cell-mediated immune responses that can be highly effective in preventing or clearing a later infection in most recipients. ./cache/cord-005400-50lmj4op.txt ./txt/cord-005400-50lmj4op.txt