id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-343896-c40fry35	Dong, Fen	Vaccination Route Determines the Kinetics and Magnitude of Nasal Innate Immune Responses in Rainbow Trout (Oncorhynchus mykiss)	2020-10-01		.txt	text/plain	5617	308	46	The goal of this study was to evaluate the ability of a live attenuated viral vaccine to stimulate innate immunity in the olfactory organ of rainbow trout, a teleost fish of commercial aquaculture value. The goal of this study is to compare the effects of three different vaccine delivery routes, including intranasal (IN), intramuscular (i.m.) injection and immersion (imm) routes on the trout nasal innate immune response. In this study, we compared three vaccination routes (intranasal (IN), intramuscular injection (i.m.) and immersion (imm) on trout nasal innate immune responses using a live attenuated IHNV vaccine and found strong and quick immune responses in the olfactory organ IN-vaccinated group. In this study, we vaccinated rainbow trout with live attenuated IHNV or PBS by different delivery routes (Figure 1a -d) and then investigated changes in expression of 13 immune-related genes at 1, 4 and 7 dpv in trout NALT by qPCR.	./cache/cord-343896-c40fry35.txt	./txt/cord-343896-c40fry35.txt