id author title date pages extension mime words sentences flesch summary cache txt cord-287067-rrsgl377 Beutels, Philippe Funding of drugs: do vaccines warrant a different approach? 2008-11-30 .txt text/plain 5432 292 46 2 The individual perception of risks of disease and risks of adverse events drives the demand Panel: Why many vaccines require a diff erent approach • Primary prevention in healthy people, but with possibility of adverse events • Unvaccinated or poorly vaccinated people may experience benefi cial or, more rarely, detrimental impact from herd immunity • Many vaccines prevent short-lived illness in very young children, causing extra family care and work loss, for which evaluation methods lack credibility and acceptability • The cost-eff ectiveness of many vaccines is highly sensitive to the choice of discount method • Some infections are eradicable • Some emerging infections (eg, SARS, pandemic infl uenza) would have a major macroeconomic impact that goes beyond lost productivity of sick people SARS=severe acute respiratory syndrome. ./cache/cord-287067-rrsgl377.txt ./txt/cord-287067-rrsgl377.txt