id author title date pages extension mime words sentences flesch summary cache txt cord-308066-lrbi5198 Childs, James E. Pre-spillover Prevention of Emerging Zoonotic Diseases: What Are the Targets and What Are the Tools? 2007 .txt text/plain 15698 714 41 The uneven standards of surveillance, humanor animal-based, for zoonotic diseases or pathogens maintained and transmitted by wildlife H R s, or even domestic species, is a global problem, readily apparent even within the United States, where investment in public health, including surveillance systems, has a long and enviable history. Following an outbreak of human monkeypox in several US states (Centers for Disease Control and Prevention 2003a; see the chapter by Regnery, this volume), local populations of indigenous North American rodents were captured and examined for infection from areas around animal-holding facilities housing African rodents imported for the pet-trade and implicated as the source of monkeypox virus (Cunha 2004; Check 2004) . National institutions charged with strategic planning for emerging diseases or intentional releases of zoonotic agents have emphasized improving diagnostic capabilities for detecting human infections, modifying the immune status of human or domestic animals through vaccines, producing better antiviral or antibacterial drugs, and enhancing human-based surveillance as an early warning system (Fauchi 2002 ; Centers for Disease Control and Prevention 1998). ./cache/cord-308066-lrbi5198.txt ./txt/cord-308066-lrbi5198.txt