id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-003970-3e58229u	Paploski, Igor Adolfo Dexheimer	Temporal Dynamics of Co-circulating Lineages of Porcine Reproductive and Respiratory Syndrome Virus	2019-11-01		.txt	text/plain	8412	363	42	Porcine reproductive and respiratory syndrome virus (PRRSV), the etiological agent of PRRS, is one of the most important endemic viruses affecting the swine industry in the United States (Holtkamp et al., 2013) and globally (Stadejek et al., 2013; VanderWaal and Deen, 2018) . Porcine reproductive and respiratory syndrome virus was first recognized almost simultaneously in Europe (Wensvoort et al., 1991) and North America (Collins et al., 1992) in the late 1980s and early 1990s, but genetic differences suggested a much earlier evolutionary divergence between the North American and European viral types. Here, we describe the temporal dynamics of PRRSV occurrence in a swine-dense region of the United States, characterizing these patterns according to ORF5 genetic lineages and sub-lineages. Porcine reproductive and respiratory syndrome virus diversity of Eastern Canada swine herds in a large sequence dataset reveals two hypervariable regions under positive selection	./cache/cord-003970-3e58229u.txt	./txt/cord-003970-3e58229u.txt