id author title date pages extension mime words sentences flesch summary cache txt cord-307133-bm9z8gss Kong, Lingcai Modeling Heterogeneity in Direct Infectious Disease Transmission in a Compartmental Model 2016-02-24 .txt text/plain 4611 247 48 Finally, we calibrated the model with the number of daily cases of severe acute respiratory syndrome (SARS) in Beijing in 2003, and the estimated parameters show that the control measures taken at that time were effective. A low level of heterogeneity results in dynamics similar to those predicted by the homogeneous-mixing model with a frequency-dependent transmission term, βSI N . The greatest difference is that at the overall level, the heterogeneity slows the transmission speed and decreases the peak sizes, which means milder disease outbreaks, because in the scenario with a high level of heterogeneity, only a small proportion of susceptible individuals have chances of coming into contact with infectious individuals and becoming infected, which results in a slower increase of the infected population. Our results show that, keeping other conditions identical, the higher is the level of heterogeneity in contact rates, the greater is the difference in the disease dynamics observed from those predicted using the homogeneous-mixing models. ./cache/cord-307133-bm9z8gss.txt ./txt/cord-307133-bm9z8gss.txt