id	sid	tid	token	lemma	pos
cord-341690-h8fqijk5	1	1	key	key	NNP
cord-341690-h8fqijk5	1	2	:	:	:
cord-341690-h8fqijk5	1	3	cord-341690-h8fqijk5	cord-341690-h8fqijk5	ADD
cord-341690-h8fqijk5	2	1	authors	author	NNS
cord-341690-h8fqijk5	2	2	:	:	:
cord-341690-h8fqijk5	2	3	Hu	Hu	NNP
cord-341690-h8fqijk5	2	4	,	,	,
cord-341690-h8fqijk5	2	5	Weiwei	Weiwei	NNP
cord-341690-h8fqijk5	2	6	;	;	:
cord-341690-h8fqijk5	2	7	Zhu	Zhu	NNP
cord-341690-h8fqijk5	2	8	,	,	,
cord-341690-h8fqijk5	2	9	Liqi	Liqi	NNP
cord-341690-h8fqijk5	2	10	;	;	:
cord-341690-h8fqijk5	2	11	Yang	Yang	NNP
cord-341690-h8fqijk5	2	12	,	,	,
cord-341690-h8fqijk5	2	13	Xing	Xing	NNP
cord-341690-h8fqijk5	2	14	;	;	:
cord-341690-h8fqijk5	2	15	Lin	Lin	NNP
cord-341690-h8fqijk5	2	16	,	,	,
cord-341690-h8fqijk5	2	17	Jian	Jian	NNP
cord-341690-h8fqijk5	2	18	;	;	:
cord-341690-h8fqijk5	2	19	Yang	Yang	NNP
cord-341690-h8fqijk5	2	20	,	,	,
cord-341690-h8fqijk5	3	1	Qian	Qian	NNP
cord-341690-h8fqijk5	3	2	title	title	NN
cord-341690-h8fqijk5	3	3	:	:	:
cord-341690-h8fqijk5	3	4	The	the	DT
cord-341690-h8fqijk5	3	5	epidermal	epidermal	JJ
cord-341690-h8fqijk5	3	6	growth	growth	NN
cord-341690-h8fqijk5	3	7	factor	factor	NN
cord-341690-h8fqijk5	3	8	receptor	receptor	NN
cord-341690-h8fqijk5	3	9	regulates	regulate	VBZ
cord-341690-h8fqijk5	3	10	cofilin	cofilin	JJ
cord-341690-h8fqijk5	3	11	activity	activity	NN
cord-341690-h8fqijk5	3	12	and	and	CC
cord-341690-h8fqijk5	3	13	promotes	promote	VBZ
cord-341690-h8fqijk5	3	14	transmissible	transmissible	JJ
cord-341690-h8fqijk5	3	15	gastroenteritis	gastroenteritis	NN
cord-341690-h8fqijk5	3	16	virus	virus	NN
cord-341690-h8fqijk5	3	17	entry	entry	NN
cord-341690-h8fqijk5	3	18	into	into	IN
cord-341690-h8fqijk5	3	19	intestinal	intestinal	JJ
cord-341690-h8fqijk5	3	20	epithelial	epithelial	JJ
cord-341690-h8fqijk5	3	21	cells	cell	NNS
cord-341690-h8fqijk5	3	22	date	date	NN
cord-341690-h8fqijk5	3	23	:	:	:
cord-341690-h8fqijk5	3	24	2016	2016	CD
cord-341690-h8fqijk5	3	25	-	-	HYPH
cord-341690-h8fqijk5	3	26	02	02	CD
cord-341690-h8fqijk5	3	27	-	-	SYM
cord-341690-h8fqijk5	3	28	25	25	CD
cord-341690-h8fqijk5	3	29	journal	journal	NN
cord-341690-h8fqijk5	3	30	:	:	:
cord-341690-h8fqijk5	4	1	Oncotarget	Oncotarget	NNP
cord-341690-h8fqijk5	4	2	DOI	DOI	NNP
cord-341690-h8fqijk5	4	3	:	:	:
cord-341690-h8fqijk5	4	4	10.18632	10.18632	CD
cord-341690-h8fqijk5	5	1	/oncotarget.7723	/oncotarget.7723	NNP
cord-341690-h8fqijk5	5	2	sha	sha	NNP
cord-341690-h8fqijk5	5	3	:	:	:
cord-341690-h8fqijk5	6	1	ebbe2e390320b9cd9399ba2e7d011df6e953971e	ebbe2e390320b9cd9399ba2e7d011df6e953971e	NNP
cord-341690-h8fqijk5	6	2	doc_id	doc_id	CD
cord-341690-h8fqijk5	6	3	:	:	:
cord-341690-h8fqijk5	6	4	341690	341690	CD
cord-341690-h8fqijk5	6	5	cord_uid	cord_uid	NNS
cord-341690-h8fqijk5	6	6	:	:	:
cord-341690-h8fqijk5	7	1	h8fqijk5	h8fqijk5	NNP
cord-341690-h8fqijk5	8	1	Transmissible	transmissible	JJ
cord-341690-h8fqijk5	8	2	gastroenteritis	gastroenteritis	NN
cord-341690-h8fqijk5	8	3	virus	virus	NN
cord-341690-h8fqijk5	8	4	(	(	-LRB-
cord-341690-h8fqijk5	8	5	TGEV	TGEV	NNP
cord-341690-h8fqijk5	8	6	)	)	-RRB-
cord-341690-h8fqijk5	8	7	,	,	,
cord-341690-h8fqijk5	8	8	a	a	DT
cord-341690-h8fqijk5	8	9	coronavirus	coronavirus	NN
cord-341690-h8fqijk5	8	10	,	,	,
cord-341690-h8fqijk5	8	11	causes	cause	VBZ
cord-341690-h8fqijk5	8	12	severe	severe	JJ
cord-341690-h8fqijk5	8	13	diarrhea	diarrhea	NN
cord-341690-h8fqijk5	8	14	and	and	CC
cord-341690-h8fqijk5	8	15	high	high	JJ
cord-341690-h8fqijk5	8	16	mortality	mortality	NN
cord-341690-h8fqijk5	8	17	in	in	IN
cord-341690-h8fqijk5	8	18	newborn	newborn	JJ
cord-341690-h8fqijk5	8	19	piglets	piglet	NNS
cord-341690-h8fqijk5	8	20	.	.	.
cord-341690-h8fqijk5	9	1	The	the	DT
cord-341690-h8fqijk5	9	2	porcine	porcine	JJ
cord-341690-h8fqijk5	9	3	intestinal	intestinal	JJ
cord-341690-h8fqijk5	9	4	epithelium	epithelium	NN
cord-341690-h8fqijk5	9	5	is	be	VBZ
cord-341690-h8fqijk5	9	6	the	the	DT
cord-341690-h8fqijk5	9	7	target	target	NN
cord-341690-h8fqijk5	9	8	of	of	IN
cord-341690-h8fqijk5	9	9	TGEV	TGEV	NNP
cord-341690-h8fqijk5	9	10	infection	infection	NN
cord-341690-h8fqijk5	9	11	,	,	,
cord-341690-h8fqijk5	9	12	but	but	CC
cord-341690-h8fqijk5	9	13	the	the	DT
cord-341690-h8fqijk5	9	14	mechanisms	mechanism	NNS
cord-341690-h8fqijk5	9	15	that	that	WDT
cord-341690-h8fqijk5	9	16	TGEV	TGEV	NNP
cord-341690-h8fqijk5	9	17	disrupts	disrupt	VBZ
cord-341690-h8fqijk5	9	18	the	the	DT
cord-341690-h8fqijk5	9	19	actin	actin	NN
cord-341690-h8fqijk5	9	20	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	9	21	and	and	CC
cord-341690-h8fqijk5	9	22	invades	invade	VBZ
cord-341690-h8fqijk5	9	23	the	the	DT
cord-341690-h8fqijk5	9	24	host	host	NN
cord-341690-h8fqijk5	9	25	epithelium	epithelium	NN
cord-341690-h8fqijk5	9	26	remain	remain	VBP
cord-341690-h8fqijk5	9	27	largely	largely	RB
cord-341690-h8fqijk5	9	28	unknown	unknown	JJ
cord-341690-h8fqijk5	9	29	.	.	.
cord-341690-h8fqijk5	10	1	We	-PRON-	PRP
cord-341690-h8fqijk5	10	2	not	not	RB
cord-341690-h8fqijk5	10	3	only	only	RB
cord-341690-h8fqijk5	10	4	found	find	VBD
cord-341690-h8fqijk5	10	5	that	that	IN
cord-341690-h8fqijk5	10	6	TGEV	TGEV	NNP
cord-341690-h8fqijk5	10	7	infection	infection	NN
cord-341690-h8fqijk5	10	8	stimulates	stimulate	VBZ
cord-341690-h8fqijk5	10	9	F	f	NN
cord-341690-h8fqijk5	10	10	-	-	HYPH
cord-341690-h8fqijk5	10	11	actin	actin	NNP
cord-341690-h8fqijk5	10	12	to	to	TO
cord-341690-h8fqijk5	10	13	gather	gather	VB
cord-341690-h8fqijk5	10	14	at	at	IN
cord-341690-h8fqijk5	10	15	the	the	DT
cord-341690-h8fqijk5	10	16	cell	cell	NN
cord-341690-h8fqijk5	10	17	membrane	membrane	NN
cord-341690-h8fqijk5	10	18	but	but	CC
cord-341690-h8fqijk5	10	19	the	the	DT
cord-341690-h8fqijk5	10	20	disruption	disruption	NN
cord-341690-h8fqijk5	10	21	of	of	IN
cord-341690-h8fqijk5	10	22	F	F	NNP
cord-341690-h8fqijk5	10	23	-	-	HYPH
cord-341690-h8fqijk5	10	24	actin	actin	NNP
cord-341690-h8fqijk5	10	25	inhibits	inhibit	VBZ
cord-341690-h8fqijk5	10	26	TGEV	TGEV	NNP
cord-341690-h8fqijk5	10	27	entry	entry	NN
cord-341690-h8fqijk5	10	28	as	as	RB
cord-341690-h8fqijk5	10	29	well	well	RB
cord-341690-h8fqijk5	10	30	.	.	.
cord-341690-h8fqijk5	11	1	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	11	2	is	be	VBZ
cord-341690-h8fqijk5	11	3	involved	involve	VBN
cord-341690-h8fqijk5	11	4	in	in	IN
cord-341690-h8fqijk5	11	5	F	F	NNP
cord-341690-h8fqijk5	11	6	-	-	HYPH
cord-341690-h8fqijk5	11	7	actin	actin	VBG
cord-341690-h8fqijk5	11	8	reorganization	reorganization	NN
cord-341690-h8fqijk5	11	9	and	and	CC
cord-341690-h8fqijk5	11	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	11	11	entry	entry	NN
cord-341690-h8fqijk5	11	12	.	.	.
cord-341690-h8fqijk5	12	1	The	the	DT
cord-341690-h8fqijk5	12	2	TGEV	TGEV	NNP
cord-341690-h8fqijk5	12	3	spike	spike	NN
cord-341690-h8fqijk5	12	4	protein	protein	NN
cord-341690-h8fqijk5	12	5	is	be	VBZ
cord-341690-h8fqijk5	12	6	capable	capable	JJ
cord-341690-h8fqijk5	12	7	of	of	IN
cord-341690-h8fqijk5	12	8	binding	bind	VBG
cord-341690-h8fqijk5	12	9	with	with	IN
cord-341690-h8fqijk5	12	10	EGFR	EGFR	NNP
cord-341690-h8fqijk5	12	11	,	,	,
cord-341690-h8fqijk5	12	12	activating	activate	VBG
cord-341690-h8fqijk5	12	13	the	the	DT
cord-341690-h8fqijk5	12	14	downstream	downstream	JJ
cord-341690-h8fqijk5	12	15	phosphoinositide-3	phosphoinositide-3	NNP
cord-341690-h8fqijk5	12	16	kinase	kinase	NN
cord-341690-h8fqijk5	12	17	(	(	-LRB-
cord-341690-h8fqijk5	12	18	PI3	PI3	NNP
cord-341690-h8fqijk5	12	19	K	K	NNP
cord-341690-h8fqijk5	12	20	)	)	-RRB-
cord-341690-h8fqijk5	12	21	,	,	,
cord-341690-h8fqijk5	12	22	then	then	RB
cord-341690-h8fqijk5	12	23	causing	cause	VBG
cord-341690-h8fqijk5	12	24	the	the	DT
cord-341690-h8fqijk5	12	25	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	12	26	of	of	IN
cord-341690-h8fqijk5	12	27	cofilin	cofilin	NN
cord-341690-h8fqijk5	12	28	and	and	CC
cord-341690-h8fqijk5	12	29	F	F	NNP
cord-341690-h8fqijk5	12	30	-	-	HYPH
cord-341690-h8fqijk5	12	31	actin	actin	VBG
cord-341690-h8fqijk5	12	32	polymerization	polymerization	NN
cord-341690-h8fqijk5	12	33	via	via	IN
cord-341690-h8fqijk5	12	34	Rac1	Rac1	NNP
cord-341690-h8fqijk5	12	35	/	/	SYM
cord-341690-h8fqijk5	12	36	Cdc42	Cdc42	NNP
cord-341690-h8fqijk5	12	37	GTPases	gtpase	NNS
cord-341690-h8fqijk5	12	38	.	.	.
cord-341690-h8fqijk5	13	1	Inhibition	inhibition	NN
cord-341690-h8fqijk5	13	2	of	of	IN
cord-341690-h8fqijk5	13	3	EGFR	EGFR	NNP
cord-341690-h8fqijk5	13	4	and	and	CC
cord-341690-h8fqijk5	13	5	PI3	PI3	NNP
cord-341690-h8fqijk5	13	6	K	K	NNP
cord-341690-h8fqijk5	13	7	decreases	decrease	VBZ
cord-341690-h8fqijk5	13	8	the	the	DT
cord-341690-h8fqijk5	13	9	entry	entry	NN
cord-341690-h8fqijk5	13	10	of	of	IN
cord-341690-h8fqijk5	13	11	TGEV	TGEV	NNP
cord-341690-h8fqijk5	13	12	.	.	.
cord-341690-h8fqijk5	14	1	EGFR	EGFR	NNP
cord-341690-h8fqijk5	14	2	is	be	VBZ
cord-341690-h8fqijk5	14	3	also	also	RB
cord-341690-h8fqijk5	14	4	the	the	DT
cord-341690-h8fqijk5	14	5	upstream	upstream	JJ
cord-341690-h8fqijk5	14	6	activator	activator	NN
cord-341690-h8fqijk5	14	7	of	of	IN
cord-341690-h8fqijk5	14	8	mitogen	mitogen	NN
cord-341690-h8fqijk5	14	9	-	-	HYPH
cord-341690-h8fqijk5	14	10	activated	activate	VBN
cord-341690-h8fqijk5	14	11	protein	protein	NN
cord-341690-h8fqijk5	14	12	kinase	kinase	NN
cord-341690-h8fqijk5	14	13	(	(	-LRB-
cord-341690-h8fqijk5	14	14	MAPK	MAPK	NNP
cord-341690-h8fqijk5	14	15	)	)	-RRB-
cord-341690-h8fqijk5	14	16	signaling	signal	VBG
cord-341690-h8fqijk5	14	17	pathways	pathway	NNS
cord-341690-h8fqijk5	14	18	that	that	WDT
cord-341690-h8fqijk5	14	19	is	be	VBZ
cord-341690-h8fqijk5	14	20	involved	involve	VBN
cord-341690-h8fqijk5	14	21	in	in	IN
cord-341690-h8fqijk5	14	22	F	F	NNP
cord-341690-h8fqijk5	14	23	-	-	HYPH
cord-341690-h8fqijk5	14	24	actin	actin	JJ
cord-341690-h8fqijk5	14	25	reorganization	reorganization	NN
cord-341690-h8fqijk5	14	26	.	.	.
cord-341690-h8fqijk5	15	1	Additionally	additionally	RB
cord-341690-h8fqijk5	15	2	,	,	,
cord-341690-h8fqijk5	15	3	lipid	lipid	NN
cord-341690-h8fqijk5	15	4	rafts	raft	NNS
cord-341690-h8fqijk5	15	5	act	act	VBP
cord-341690-h8fqijk5	15	6	as	as	IN
cord-341690-h8fqijk5	15	7	signal	signal	NN
cord-341690-h8fqijk5	15	8	platforms	platform	NNS
cord-341690-h8fqijk5	15	9	for	for	IN
cord-341690-h8fqijk5	15	10	the	the	DT
cord-341690-h8fqijk5	15	11	EGFR	EGFR	NNP
cord-341690-h8fqijk5	15	12	-	-	HYPH
cord-341690-h8fqijk5	15	13	associated	associate	VBN
cord-341690-h8fqijk5	15	14	signaling	signal	VBG
cord-341690-h8fqijk5	15	15	cascade	cascade	NN
cord-341690-h8fqijk5	15	16	and	and	CC
cord-341690-h8fqijk5	15	17	correlate	correlate	VB
cord-341690-h8fqijk5	15	18	with	with	IN
cord-341690-h8fqijk5	15	19	the	the	DT
cord-341690-h8fqijk5	15	20	adhesion	adhesion	NN
cord-341690-h8fqijk5	15	21	of	of	IN
cord-341690-h8fqijk5	15	22	TGEV	TGEV	NNP
cord-341690-h8fqijk5	15	23	.	.	.
cord-341690-h8fqijk5	16	1	In	in	IN
cord-341690-h8fqijk5	16	2	conlusion	conlusion	NN
cord-341690-h8fqijk5	16	3	,	,	,
cord-341690-h8fqijk5	16	4	these	these	DT
cord-341690-h8fqijk5	16	5	results	result	NNS
cord-341690-h8fqijk5	16	6	provide	provide	VBP
cord-341690-h8fqijk5	16	7	valuable	valuable	JJ
cord-341690-h8fqijk5	16	8	data	datum	NNS
cord-341690-h8fqijk5	16	9	of	of	IN
cord-341690-h8fqijk5	16	10	the	the	DT
cord-341690-h8fqijk5	16	11	mechanisms	mechanism	NNS
cord-341690-h8fqijk5	16	12	which	which	WDT
cord-341690-h8fqijk5	16	13	are	be	VBP
cord-341690-h8fqijk5	16	14	responsible	responsible	JJ
cord-341690-h8fqijk5	16	15	for	for	IN
cord-341690-h8fqijk5	16	16	the	the	DT
cord-341690-h8fqijk5	16	17	TGEV	TGEV	NNP
cord-341690-h8fqijk5	16	18	pathogenesis	pathogenesis	NN
cord-341690-h8fqijk5	16	19	and	and	CC
cord-341690-h8fqijk5	16	20	may	may	MD
cord-341690-h8fqijk5	16	21	lead	lead	VB
cord-341690-h8fqijk5	16	22	to	to	IN
cord-341690-h8fqijk5	16	23	the	the	DT
cord-341690-h8fqijk5	16	24	development	development	NN
cord-341690-h8fqijk5	16	25	of	of	IN
cord-341690-h8fqijk5	16	26	new	new	JJ
cord-341690-h8fqijk5	16	27	methods	method	NNS
cord-341690-h8fqijk5	16	28	about	about	IN
cord-341690-h8fqijk5	16	29	controlling	control	VBG
cord-341690-h8fqijk5	16	30	TGEV	TGEV	NNP
cord-341690-h8fqijk5	16	31	.	.	.
cord-341690-h8fqijk5	17	1	is	be	VBZ
cord-341690-h8fqijk5	17	2	an	an	DT
cord-341690-h8fqijk5	17	3	enveloped	envelop	VBN
cord-341690-h8fqijk5	17	4	enteropathogenic	enteropathogenic	JJ
cord-341690-h8fqijk5	17	5	coronavirus	coronavirus	NN
cord-341690-h8fqijk5	17	6	(	(	-LRB-
cord-341690-h8fqijk5	17	7	CoV	CoV	NNP
cord-341690-h8fqijk5	17	8	)	)	-RRB-
cord-341690-h8fqijk5	17	9	with	with	IN
cord-341690-h8fqijk5	17	10	a	a	DT
cord-341690-h8fqijk5	17	11	large	large	JJ
cord-341690-h8fqijk5	17	12	positive	positive	JJ
cord-341690-h8fqijk5	17	13	-	-	HYPH
cord-341690-h8fqijk5	17	14	sense	sense	NN
cord-341690-h8fqijk5	17	15	single	single	JJ
cord-341690-h8fqijk5	17	16	-	-	HYPH
cord-341690-h8fqijk5	17	17	stranded	strand	VBN
cord-341690-h8fqijk5	17	18	RNA	RNA	NNP
cord-341690-h8fqijk5	17	19	genome	genome	NN
cord-341690-h8fqijk5	17	20	about	about	IN
cord-341690-h8fqijk5	17	21	28.5	28.5	CD
cord-341690-h8fqijk5	17	22	kb	kb	NNP
cord-341690-h8fqijk5	17	23	in	in	IN
cord-341690-h8fqijk5	17	24	length	length	NN
cord-341690-h8fqijk5	17	25	.	.	.
cord-341690-h8fqijk5	18	1	Similar	similar	JJ
cord-341690-h8fqijk5	18	2	to	to	IN
cord-341690-h8fqijk5	18	3	other	other	JJ
cord-341690-h8fqijk5	18	4	CoVs	CoVs	NNP
cord-341690-h8fqijk5	18	5	,	,	,
cord-341690-h8fqijk5	18	6	TGEV	TGEV	NNP
cord-341690-h8fqijk5	18	7	has	have	VBZ
cord-341690-h8fqijk5	18	8	a	a	DT
cord-341690-h8fqijk5	18	9	diameter	diameter	NN
cord-341690-h8fqijk5	18	10	ranging	range	VBG
cord-341690-h8fqijk5	18	11	from	from	IN
cord-341690-h8fqijk5	18	12	100	100	CD
cord-341690-h8fqijk5	18	13	to	to	TO
cord-341690-h8fqijk5	18	14	150	150	CD
cord-341690-h8fqijk5	18	15	nm	nm	NN
cord-341690-h8fqijk5	18	16	,	,	,
cord-341690-h8fqijk5	18	17	including	include	VBG
cord-341690-h8fqijk5	18	18	the	the	DT
cord-341690-h8fqijk5	18	19	surface	surface	NN
cord-341690-h8fqijk5	18	20	projections	projection	NNS
cord-341690-h8fqijk5	18	21	.	.	.
cord-341690-h8fqijk5	19	1	TGEV	TGEV	NNP
cord-341690-h8fqijk5	19	2	infects	infect	VBZ
cord-341690-h8fqijk5	19	3	newborn	newborn	JJ
cord-341690-h8fqijk5	19	4	piglets	piglet	NNS
cord-341690-h8fqijk5	19	5	with	with	IN
cord-341690-h8fqijk5	19	6	mortality	mortality	NN
cord-341690-h8fqijk5	19	7	rates	rate	NNS
cord-341690-h8fqijk5	19	8	reaching	reach	VBG
cord-341690-h8fqijk5	19	9	100	100	CD
cord-341690-h8fqijk5	19	10	%	%	NN
cord-341690-h8fqijk5	19	11	,	,	,
cord-341690-h8fqijk5	19	12	resulting	result	VBG
cord-341690-h8fqijk5	19	13	in	in	IN
cord-341690-h8fqijk5	19	14	significant	significant	JJ
cord-341690-h8fqijk5	19	15	losses	loss	NNS
cord-341690-h8fqijk5	19	16	in	in	IN
cord-341690-h8fqijk5	19	17	the	the	DT
cord-341690-h8fqijk5	19	18	swine	swine	NN
cord-341690-h8fqijk5	19	19	industry	industry	NN
cord-341690-h8fqijk5	19	20	.	.	.
cord-341690-h8fqijk5	20	1	The	the	DT
cord-341690-h8fqijk5	20	2	CoV	cov	NN
cord-341690-h8fqijk5	20	3	spike	spike	NN
cord-341690-h8fqijk5	20	4	protein	protein	NN
cord-341690-h8fqijk5	20	5	binds	bind	VBZ
cord-341690-h8fqijk5	20	6	to	to	IN
cord-341690-h8fqijk5	20	7	a	a	DT
cord-341690-h8fqijk5	20	8	cellular	cellular	JJ
cord-341690-h8fqijk5	20	9	receptor	receptor	NN
cord-341690-h8fqijk5	20	10	and	and	CC
cord-341690-h8fqijk5	20	11	then	then	RB
cord-341690-h8fqijk5	20	12	mediates	mediate	VBZ
cord-341690-h8fqijk5	20	13	membrane	membrane	NN
cord-341690-h8fqijk5	20	14	fusion	fusion	NN
cord-341690-h8fqijk5	20	15	at	at	IN
cord-341690-h8fqijk5	20	16	the	the	DT
cord-341690-h8fqijk5	20	17	plasma	plasma	NN
cord-341690-h8fqijk5	20	18	membrane	membrane	NN
cord-341690-h8fqijk5	20	19	or	or	CC
cord-341690-h8fqijk5	20	20	by	by	IN
cord-341690-h8fqijk5	20	21	endosomal	endosomal	NNP
cord-341690-h8fqijk5	20	22	uptake	uptake	NN
cord-341690-h8fqijk5	20	23	.	.	.
cord-341690-h8fqijk5	21	1	TGEV	TGEV	NNP
cord-341690-h8fqijk5	21	2	,	,	,
cord-341690-h8fqijk5	21	3	Human	human	JJ
cord-341690-h8fqijk5	21	4	coronavirus	coronavirus	NN
cord-341690-h8fqijk5	21	5	(	(	-LRB-
cord-341690-h8fqijk5	21	6	HCoV-229E	HCoV-229E	NNP
cord-341690-h8fqijk5	21	7	)	)	-RRB-
cord-341690-h8fqijk5	21	8	,	,	,
cord-341690-h8fqijk5	21	9	serotype	serotype	NN
cord-341690-h8fqijk5	21	10	2	2	CD
cord-341690-h8fqijk5	21	11	Feline	Feline	NNP
cord-341690-h8fqijk5	21	12	Coronavirus	Coronavirus	NNP
cord-341690-h8fqijk5	21	13	(	(	-LRB-
cord-341690-h8fqijk5	21	14	FCoV	FCoV	NNP
cord-341690-h8fqijk5	21	15	)	)	-RRB-
cord-341690-h8fqijk5	21	16	,	,	,
cord-341690-h8fqijk5	21	17	and	and	CC
cord-341690-h8fqijk5	21	18	Canine	Canine	NNP
cord-341690-h8fqijk5	21	19	Coronavirus	Coronavirus	NNP
cord-341690-h8fqijk5	21	20	(	(	-LRB-
cord-341690-h8fqijk5	21	21	CCoV	ccov	ADD
cord-341690-h8fqijk5	21	22	)	)	-RRB-
cord-341690-h8fqijk5	22	1	all	all	DT
cord-341690-h8fqijk5	22	2	use	use	VBP
cord-341690-h8fqijk5	22	3	the	the	DT
cord-341690-h8fqijk5	22	4	aminopeptidase	aminopeptidase	NN
cord-341690-h8fqijk5	22	5	N	N	NNP
cord-341690-h8fqijk5	22	6	(	(	-LRB-
cord-341690-h8fqijk5	22	7	APN	APN	NNP
cord-341690-h8fqijk5	22	8	)	)	-RRB-
cord-341690-h8fqijk5	22	9	protein	protein	NN
cord-341690-h8fqijk5	22	10	as	as	IN
cord-341690-h8fqijk5	22	11	the	the	DT
cord-341690-h8fqijk5	22	12	receptor	receptor	NN
cord-341690-h8fqijk5	22	13	[	[	-LRB-
cord-341690-h8fqijk5	22	14	1	1	CD
cord-341690-h8fqijk5	22	15	]	]	-RRB-
cord-341690-h8fqijk5	22	16	.	.	.
cord-341690-h8fqijk5	23	1	TGEV	TGEV	NNP
cord-341690-h8fqijk5	23	2	infects	infect	VBZ
cord-341690-h8fqijk5	23	3	epithelial	epithelial	JJ
cord-341690-h8fqijk5	23	4	cells	cell	NNS
cord-341690-h8fqijk5	23	5	through	through	IN
cord-341690-h8fqijk5	23	6	the	the	DT
cord-341690-h8fqijk5	23	7	small	small	JJ
cord-341690-h8fqijk5	23	8	intestine	intestine	NN
cord-341690-h8fqijk5	23	9	and	and	CC
cord-341690-h8fqijk5	23	10	the	the	DT
cord-341690-h8fqijk5	23	11	respiratory	respiratory	JJ
cord-341690-h8fqijk5	23	12	tract	tract	NN
cord-341690-h8fqijk5	23	13	.	.	.
cord-341690-h8fqijk5	24	1	The	the	DT
cord-341690-h8fqijk5	24	2	virus	virus	NN
cord-341690-h8fqijk5	24	3	enters	enter	VBZ
cord-341690-h8fqijk5	24	4	epithelial	epithelial	JJ
cord-341690-h8fqijk5	24	5	cells	cell	NNS
cord-341690-h8fqijk5	24	6	from	from	IN
cord-341690-h8fqijk5	24	7	the	the	DT
cord-341690-h8fqijk5	24	8	apical	apical	JJ
cord-341690-h8fqijk5	24	9	or	or	CC
cord-341690-h8fqijk5	24	10	basolateral	basolateral	JJ
cord-341690-h8fqijk5	24	11	side	side	NN
cord-341690-h8fqijk5	24	12	,	,	,
cord-341690-h8fqijk5	24	13	and	and	CC
cord-341690-h8fqijk5	24	14	is	be	VBZ
cord-341690-h8fqijk5	24	15	released	release	VBN
cord-341690-h8fqijk5	24	16	from	from	IN
cord-341690-h8fqijk5	24	17	the	the	DT
cord-341690-h8fqijk5	24	18	apical	apical	JJ
cord-341690-h8fqijk5	24	19	plasma	plasma	NN
cord-341690-h8fqijk5	24	20	membrane	membrane	NN
cord-341690-h8fqijk5	24	21	into	into	IN
cord-341690-h8fqijk5	24	22	the	the	DT
cord-341690-h8fqijk5	24	23	gut	gut	NN
cord-341690-h8fqijk5	24	24	lumen	lumen	NN
cord-341690-h8fqijk5	24	25	,	,	,
cord-341690-h8fqijk5	24	26	where	where	WRB
cord-341690-h8fqijk5	24	27	it	-PRON-	PRP
cord-341690-h8fqijk5	24	28	propagates	propagate	VBZ
cord-341690-h8fqijk5	24	29	efficiently	efficiently	RB
cord-341690-h8fqijk5	24	30	by	by	IN
cord-341690-h8fqijk5	24	31	cell	cell	NN
cord-341690-h8fqijk5	24	32	-	-	HYPH
cord-341690-h8fqijk5	24	33	to	to	IN
cord-341690-h8fqijk5	24	34	-	-	HYPH
cord-341690-h8fqijk5	24	35	cell	cell	NN
cord-341690-h8fqijk5	24	36	spreading	spread	VBG
cord-341690-h8fqijk5	24	37	[	[	-LRB-
cord-341690-h8fqijk5	24	38	2	2	CD
cord-341690-h8fqijk5	24	39	]	]	-RRB-
cord-341690-h8fqijk5	24	40	.	.	.
cord-341690-h8fqijk5	25	1	Porcine	porcine	JJ
cord-341690-h8fqijk5	25	2	intestinal	intestinal	JJ
cord-341690-h8fqijk5	25	3	columnar	columnar	JJ
cord-341690-h8fqijk5	25	4	epithelial	epithelial	JJ
cord-341690-h8fqijk5	25	5	cells	cell	NNS
cord-341690-h8fqijk5	25	6	(	(	-LRB-
cord-341690-h8fqijk5	25	7	IPEC	IPEC	NNP
cord-341690-h8fqijk5	25	8	-	-	HYPH
cord-341690-h8fqijk5	25	9	J2	J2	NNP
cord-341690-h8fqijk5	25	10	)	)	-RRB-
cord-341690-h8fqijk5	25	11	offer	offer	VBP
cord-341690-h8fqijk5	25	12	a	a	DT
cord-341690-h8fqijk5	25	13	practical	practical	JJ
cord-341690-h8fqijk5	25	14	model	model	NN
cord-341690-h8fqijk5	25	15	for	for	IN
cord-341690-h8fqijk5	25	16	studying	study	VBG
cord-341690-h8fqijk5	25	17	porcine	porcine	JJ
cord-341690-h8fqijk5	25	18	enteric	enteric	JJ
cord-341690-h8fqijk5	25	19	pathogens	pathogen	NNS
cord-341690-h8fqijk5	25	20	[	[	-LRB-
cord-341690-h8fqijk5	25	21	3	3	CD
cord-341690-h8fqijk5	25	22	]	]	-RRB-
cord-341690-h8fqijk5	25	23	.	.	.
cord-341690-h8fqijk5	26	1	However	however	RB
cord-341690-h8fqijk5	26	2	,	,	,
cord-341690-h8fqijk5	26	3	the	the	DT
cord-341690-h8fqijk5	26	4	precise	precise	JJ
cord-341690-h8fqijk5	26	5	molecular	molecular	JJ
cord-341690-h8fqijk5	26	6	mechanisms	mechanism	NNS
cord-341690-h8fqijk5	26	7	responsible	responsible	JJ
cord-341690-h8fqijk5	26	8	for	for	IN
cord-341690-h8fqijk5	26	9	TGEV	TGEV	NNP
cord-341690-h8fqijk5	26	10	entry	entry	NN
cord-341690-h8fqijk5	26	11	are	be	VBP
cord-341690-h8fqijk5	26	12	largely	largely	RB
cord-341690-h8fqijk5	26	13	unknown	unknown	JJ
cord-341690-h8fqijk5	26	14	,	,	,
cord-341690-h8fqijk5	26	15	and	and	CC
cord-341690-h8fqijk5	26	16	limited	limited	JJ
cord-341690-h8fqijk5	26	17	informations	information	NNS
cord-341690-h8fqijk5	26	18	are	be	VBP
cord-341690-h8fqijk5	26	19	available	available	JJ
cord-341690-h8fqijk5	26	20	on	on	IN
cord-341690-h8fqijk5	26	21	the	the	DT
cord-341690-h8fqijk5	26	22	cell	cell	NN
cord-341690-h8fqijk5	26	23	signaling	signal	VBG
cord-341690-h8fqijk5	26	24	pathways	pathway	NNS
cord-341690-h8fqijk5	26	25	involved	involve	VBN
cord-341690-h8fqijk5	26	26	in	in	IN
cord-341690-h8fqijk5	26	27	coronavirus	coronavirus	NN
cord-341690-h8fqijk5	26	28	entry	entry	NN
cord-341690-h8fqijk5	26	29	via	via	IN
cord-341690-h8fqijk5	26	30	the	the	DT
cord-341690-h8fqijk5	26	31	actin	actin	NN
cord-341690-h8fqijk5	26	32	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	26	33	.	.	.
cord-341690-h8fqijk5	27	1	Located	locate	VBN
cord-341690-h8fqijk5	27	2	beneath	beneath	IN
cord-341690-h8fqijk5	27	3	the	the	DT
cord-341690-h8fqijk5	27	4	plasma	plasma	NN
cord-341690-h8fqijk5	27	5	membrane	membrane	NN
cord-341690-h8fqijk5	27	6	,	,	,
cord-341690-h8fqijk5	27	7	cortical	cortical	JJ
cord-341690-h8fqijk5	27	8	actin	actin	NN
cord-341690-h8fqijk5	27	9	is	be	VBZ
cord-341690-h8fqijk5	27	10	composed	compose	VBN
cord-341690-h8fqijk5	27	11	of	of	IN
cord-341690-h8fqijk5	27	12	a	a	DT
cord-341690-h8fqijk5	27	13	loosely	loosely	RB
cord-341690-h8fqijk5	27	14	organized	organize	VBN
cord-341690-h8fqijk5	27	15	network	network	NN
cord-341690-h8fqijk5	27	16	of	of	IN
cord-341690-h8fqijk5	27	17	actin	actin	NN
cord-341690-h8fqijk5	27	18	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	27	19	that	that	WDT
cord-341690-h8fqijk5	27	20	is	be	VBZ
cord-341690-h8fqijk5	27	21	highly	highly	RB
cord-341690-h8fqijk5	27	22	dynamic	dynamic	JJ
cord-341690-h8fqijk5	27	23	and	and	CC
cord-341690-h8fqijk5	27	24	is	be	VBZ
cord-341690-h8fqijk5	27	25	involved	involve	VBN
cord-341690-h8fqijk5	27	26	in	in	IN
cord-341690-h8fqijk5	27	27	many	many	JJ
cord-341690-h8fqijk5	27	28	cellular	cellular	JJ
cord-341690-h8fqijk5	27	29	processes	process	NNS
cord-341690-h8fqijk5	27	30	.	.	.
cord-341690-h8fqijk5	28	1	Many	many	JJ
cord-341690-h8fqijk5	28	2	pathogens	pathogen	NNS
cord-341690-h8fqijk5	28	3	facilitate	facilitate	VBP
cord-341690-h8fqijk5	28	4	cell	cell	NN
cord-341690-h8fqijk5	28	5	entry	entry	NN
cord-341690-h8fqijk5	28	6	and/or	and/or	CC
cord-341690-h8fqijk5	28	7	trafficking	trafficking	NN
cord-341690-h8fqijk5	28	8	by	by	IN
cord-341690-h8fqijk5	28	9	stimulating	stimulate	VBG
cord-341690-h8fqijk5	28	10	actin	actin	NN
cord-341690-h8fqijk5	28	11	remodeling	remodeling	NN
cord-341690-h8fqijk5	28	12	[	[	-LRB-
cord-341690-h8fqijk5	28	13	4	4	CD
cord-341690-h8fqijk5	28	14	,	,	,
cord-341690-h8fqijk5	28	15	5	5	CD
cord-341690-h8fqijk5	28	16	]	]	-RRB-
cord-341690-h8fqijk5	28	17	.	.	.
cord-341690-h8fqijk5	29	1	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	29	2	plays	play	VBZ
cord-341690-h8fqijk5	29	3	an	an	DT
cord-341690-h8fqijk5	29	4	important	important	JJ
cord-341690-h8fqijk5	29	5	role	role	NN
cord-341690-h8fqijk5	29	6	in	in	IN
cord-341690-h8fqijk5	29	7	actin	actin	NN
cord-341690-h8fqijk5	29	8	polymerization	polymerization	NN
cord-341690-h8fqijk5	29	9	and	and	CC
cord-341690-h8fqijk5	29	10	depolymerization	depolymerization	NN
cord-341690-h8fqijk5	29	11	[	[	-LRB-
cord-341690-h8fqijk5	29	12	6	6	CD
cord-341690-h8fqijk5	29	13	]	]	-RRB-
cord-341690-h8fqijk5	29	14	.	.	.
cord-341690-h8fqijk5	30	1	LIM	LIM	NNP
cord-341690-h8fqijk5	30	2	-	-	HYPH
cord-341690-h8fqijk5	30	3	kinases	kinase	NNS
cord-341690-h8fqijk5	30	4	(	(	-LRB-
cord-341690-h8fqijk5	30	5	LIMKs	limk	NNS
cord-341690-h8fqijk5	30	6	)	)	-RRB-
cord-341690-h8fqijk5	30	7	inhibit	inhibit	VBP
cord-341690-h8fqijk5	30	8	the	the	DT
cord-341690-h8fqijk5	30	9	activity	activity	NN
cord-341690-h8fqijk5	30	10	of	of	IN
cord-341690-h8fqijk5	30	11	cofilin	cofilin	NN
cord-341690-h8fqijk5	30	12	by	by	IN
cord-341690-h8fqijk5	30	13	phosphorylating	phosphorylate	VBG
cord-341690-h8fqijk5	30	14	the	the	DT
cord-341690-h8fqijk5	30	15	serine	serine	NN
cord-341690-h8fqijk5	30	16	residue	residue	NN
cord-341690-h8fqijk5	30	17	at	at	IN
cord-341690-h8fqijk5	30	18	position	position	NN
cord-341690-h8fqijk5	30	19	3	3	CD
cord-341690-h8fqijk5	30	20	(	(	-LRB-
cord-341690-h8fqijk5	30	21	Ser-3	Ser-3	NNP
cord-341690-h8fqijk5	30	22	)	)	-RRB-
cord-341690-h8fqijk5	30	23	.	.	.
cord-341690-h8fqijk5	31	1	LIMKs	limk	NNS
cord-341690-h8fqijk5	31	2	are	be	VBP
cord-341690-h8fqijk5	31	3	activated	activate	VBN
cord-341690-h8fqijk5	31	4	by	by	IN
cord-341690-h8fqijk5	31	5	Rho	rho	NN
cord-341690-h8fqijk5	31	6	-	-	HYPH
cord-341690-h8fqijk5	31	7	associated	associate	VBN
cord-341690-h8fqijk5	31	8	kinase	kinase	NN
cord-341690-h8fqijk5	31	9	(	(	-LRB-
cord-341690-h8fqijk5	31	10	ROCK	ROCK	NNP
cord-341690-h8fqijk5	31	11	)	)	-RRB-
cord-341690-h8fqijk5	31	12	,	,	,
cord-341690-h8fqijk5	31	13	p21-activated	p21-activate	VBN
cord-341690-h8fqijk5	31	14	protein	protein	NN
cord-341690-h8fqijk5	31	15	kinases	kinase	NNS
cord-341690-h8fqijk5	31	16	(	(	-LRB-
cord-341690-h8fqijk5	31	17	PAKs	PAKs	NNP
cord-341690-h8fqijk5	31	18	)	)	-RRB-
cord-341690-h8fqijk5	31	19	,	,	,
cord-341690-h8fqijk5	31	20	which	which	WDT
cord-341690-h8fqijk5	31	21	are	be	VBP
cord-341690-h8fqijk5	31	22	downstream	downstream	JJ
cord-341690-h8fqijk5	31	23	kinases	kinase	NNS
cord-341690-h8fqijk5	31	24	of	of	IN
cord-341690-h8fqijk5	31	25	the	the	DT
cord-341690-h8fqijk5	31	26	Rho	Rho	NNP
cord-341690-h8fqijk5	31	27	family	family	NN
cord-341690-h8fqijk5	31	28	GTPases	gtpase	NNS
cord-341690-h8fqijk5	31	29	,	,	,
cord-341690-h8fqijk5	31	30	RhoA	RhoA	NNP
cord-341690-h8fqijk5	31	31	,	,	,
cord-341690-h8fqijk5	31	32	Rac1	Rac1	NNP
cord-341690-h8fqijk5	31	33	,	,	,
cord-341690-h8fqijk5	31	34	and	and	CC
cord-341690-h8fqijk5	31	35	Cdc42	Cdc42	NNP
cord-341690-h8fqijk5	31	36	[	[	-LRB-
cord-341690-h8fqijk5	31	37	7	7	CD
cord-341690-h8fqijk5	31	38	]	]	-RRB-
cord-341690-h8fqijk5	31	39	.	.	.
cord-341690-h8fqijk5	32	1	Rho	Rho	NNP
cord-341690-h8fqijk5	32	2	GTPases	gtpase	NNS
cord-341690-h8fqijk5	32	3	regulate	regulate	VBP
cord-341690-h8fqijk5	32	4	actin	actin	NN
cord-341690-h8fqijk5	32	5	polymerization	polymerization	NN
cord-341690-h8fqijk5	32	6	,	,	,
cord-341690-h8fqijk5	32	7	induce	induce	VB
cord-341690-h8fqijk5	32	8	plasma	plasma	NN
cord-341690-h8fqijk5	32	9	membrane	membrane	NN
cord-341690-h8fqijk5	32	10	protrusion	protrusion	NN
cord-341690-h8fqijk5	32	11	and	and	CC
cord-341690-h8fqijk5	32	12	control	control	NN
cord-341690-h8fqijk5	32	13	vesicle	vesicle	NN
cord-341690-h8fqijk5	32	14	trafficking	traffic	VBG
cord-341690-h8fqijk5	32	15	[	[	-LRB-
cord-341690-h8fqijk5	32	16	8	8	CD
cord-341690-h8fqijk5	32	17	]	]	-RRB-
cord-341690-h8fqijk5	32	18	.	.	.
cord-341690-h8fqijk5	33	1	The	the	DT
cord-341690-h8fqijk5	33	2	phosphoinositide-3	phosphoinositide-3	NNP
cord-341690-h8fqijk5	33	3	kinase	kinase	NN
cord-341690-h8fqijk5	33	4	(	(	-LRB-
cord-341690-h8fqijk5	33	5	PI3	PI3	NNP
cord-341690-h8fqijk5	33	6	K	K	NNP
cord-341690-h8fqijk5	33	7	)	)	-RRB-
cord-341690-h8fqijk5	33	8	pathway	pathway	NN
cord-341690-h8fqijk5	33	9	is	be	VBZ
cord-341690-h8fqijk5	33	10	activated	activate	VBN
cord-341690-h8fqijk5	33	11	by	by	IN
cord-341690-h8fqijk5	33	12	a	a	DT
cord-341690-h8fqijk5	33	13	variety	variety	NN
cord-341690-h8fqijk5	33	14	of	of	IN
cord-341690-h8fqijk5	33	15	extracellular	extracellular	JJ
cord-341690-h8fqijk5	33	16	stimuli	stimulus	NNS
cord-341690-h8fqijk5	33	17	and	and	CC
cord-341690-h8fqijk5	33	18	regulates	regulate	VBZ
cord-341690-h8fqijk5	33	19	a	a	DT
cord-341690-h8fqijk5	33	20	wide	wide	JJ
cord-341690-h8fqijk5	33	21	range	range	NN
cord-341690-h8fqijk5	33	22	of	of	IN
cord-341690-h8fqijk5	33	23	cellular	cellular	JJ
cord-341690-h8fqijk5	33	24	processes	process	NNS
cord-341690-h8fqijk5	33	25	,	,	,
cord-341690-h8fqijk5	33	26	including	include	VBG
cord-341690-h8fqijk5	33	27	cell	cell	NN
cord-341690-h8fqijk5	33	28	cycle	cycle	NN
cord-341690-h8fqijk5	33	29	progression	progression	NN
cord-341690-h8fqijk5	33	30	,	,	,
cord-341690-h8fqijk5	33	31	cell	cell	NN
cord-341690-h8fqijk5	33	32	growth	growth	NN
cord-341690-h8fqijk5	33	33	,	,	,
cord-341690-h8fqijk5	33	34	cell	cell	NN
cord-341690-h8fqijk5	33	35	motility	motility	NN
cord-341690-h8fqijk5	33	36	,	,	,
cord-341690-h8fqijk5	33	37	cell	cell	NN
cord-341690-h8fqijk5	33	38	adhesion	adhesion	NN
cord-341690-h8fqijk5	33	39	and	and	CC
cord-341690-h8fqijk5	33	40	vesicular	vesicular	JJ
cord-341690-h8fqijk5	33	41	trafficking	trafficking	NN
cord-341690-h8fqijk5	33	42	[	[	-LRB-
cord-341690-h8fqijk5	33	43	9	9	CD
cord-341690-h8fqijk5	33	44	,	,	,
cord-341690-h8fqijk5	33	45	10	10	CD
cord-341690-h8fqijk5	33	46	]	]	-RRB-
cord-341690-h8fqijk5	33	47	.	.	.
cord-341690-h8fqijk5	34	1	The	the	DT
cord-341690-h8fqijk5	34	2	serine	serine	NN
cord-341690-h8fqijk5	34	3	/	/	SYM
cord-341690-h8fqijk5	34	4	threonine	threonine	NN
cord-341690-h8fqijk5	34	5	kinase	kinase	NN
cord-341690-h8fqijk5	34	6	(	(	-LRB-
cord-341690-h8fqijk5	34	7	Akt	Akt	NNP
cord-341690-h8fqijk5	34	8	)	)	-RRB-
cord-341690-h8fqijk5	34	9	is	be	VBZ
cord-341690-h8fqijk5	34	10	a	a	DT
cord-341690-h8fqijk5	34	11	central	central	JJ
cord-341690-h8fqijk5	34	12	node	node	NN
cord-341690-h8fqijk5	34	13	in	in	IN
cord-341690-h8fqijk5	34	14	cell	cell	NN
cord-341690-h8fqijk5	34	15	signaling	signal	VBG
cord-341690-h8fqijk5	34	16	downstream	downstream	NN
cord-341690-h8fqijk5	34	17	of	of	IN
cord-341690-h8fqijk5	34	18	growth	growth	NN
cord-341690-h8fqijk5	34	19	factors	factor	NNS
cord-341690-h8fqijk5	34	20	,	,	,
cord-341690-h8fqijk5	34	21	cytokines	cytokine	NNS
cord-341690-h8fqijk5	34	22	,	,	,
cord-341690-h8fqijk5	34	23	and	and	CC
cord-341690-h8fqijk5	34	24	other	other	JJ
cord-341690-h8fqijk5	34	25	cellular	cellular	JJ
cord-341690-h8fqijk5	34	26	stimuli	stimulus	NNS
cord-341690-h8fqijk5	34	27	[	[	-LRB-
cord-341690-h8fqijk5	34	28	11	11	CD
cord-341690-h8fqijk5	34	29	]	]	-RRB-
cord-341690-h8fqijk5	34	30	.	.	.
cord-341690-h8fqijk5	35	1	Receptor	receptor	NN
cord-341690-h8fqijk5	35	2	tyrosine	tyrosine	NN
cord-341690-h8fqijk5	35	3	kinases	kinase	NNS
cord-341690-h8fqijk5	35	4	(	(	-LRB-
cord-341690-h8fqijk5	35	5	RTKs	RTKs	NNP
cord-341690-h8fqijk5	35	6	)	)	-RRB-
cord-341690-h8fqijk5	35	7	play	play	VB
cord-341690-h8fqijk5	35	8	an	an	DT
cord-341690-h8fqijk5	35	9	important	important	JJ
cord-341690-h8fqijk5	35	10	role	role	NN
cord-341690-h8fqijk5	35	11	in	in	IN
cord-341690-h8fqijk5	35	12	transforming	transform	VBG
cord-341690-h8fqijk5	35	13	extracellular	extracellular	JJ
cord-341690-h8fqijk5	35	14	intracellular	intracellular	JJ
cord-341690-h8fqijk5	35	15	signals	signal	NNS
cord-341690-h8fqijk5	35	16	and	and	CC
cord-341690-h8fqijk5	35	17	activate	activate	VB
cord-341690-h8fqijk5	35	18	PI3	PI3	NNP
cord-341690-h8fqijk5	35	19	K	K	NNP
cord-341690-h8fqijk5	35	20	as	as	RB
cord-341690-h8fqijk5	35	21	well	well	RB
cord-341690-h8fqijk5	35	22	as	as	IN
cord-341690-h8fqijk5	35	23	extracellular	extracellular	JJ
cord-341690-h8fqijk5	35	24	signal	signal	NN
cord-341690-h8fqijk5	35	25	regulated	regulate	VBN
cord-341690-h8fqijk5	35	26	kinase	kinase	NN
cord-341690-h8fqijk5	35	27	(	(	-LRB-
cord-341690-h8fqijk5	35	28	ERK)1/2	ERK)1/2	NNP
cord-341690-h8fqijk5	35	29	[	[	-LRB-
cord-341690-h8fqijk5	35	30	12	12	CD
cord-341690-h8fqijk5	35	31	]	]	-RRB-
cord-341690-h8fqijk5	35	32	.	.	.
cord-341690-h8fqijk5	36	1	The	the	DT
cord-341690-h8fqijk5	36	2	epidermal	epidermal	JJ
cord-341690-h8fqijk5	36	3	growth	growth	NN
cord-341690-h8fqijk5	36	4	factor	factor	NN
cord-341690-h8fqijk5	36	5	receptor	receptor	NN
cord-341690-h8fqijk5	36	6	(	(	-LRB-
cord-341690-h8fqijk5	36	7	EGFR	EGFR	NNP
cord-341690-h8fqijk5	36	8	)	)	-RRB-
cord-341690-h8fqijk5	36	9	belongs	belong	VBZ
cord-341690-h8fqijk5	36	10	to	to	IN
cord-341690-h8fqijk5	36	11	the	the	DT
cord-341690-h8fqijk5	36	12	RTK	RTK	NNP
cord-341690-h8fqijk5	36	13	family	family	NN
cord-341690-h8fqijk5	36	14	,	,	,
cord-341690-h8fqijk5	36	15	and	and	CC
cord-341690-h8fqijk5	36	16	is	be	VBZ
cord-341690-h8fqijk5	36	17	activated	activate	VBN
cord-341690-h8fqijk5	36	18	by	by	IN
cord-341690-h8fqijk5	36	19	a	a	DT
cord-341690-h8fqijk5	36	20	family	family	NN
cord-341690-h8fqijk5	36	21	of	of	IN
cord-341690-h8fqijk5	36	22	growth	growth	NN
cord-341690-h8fqijk5	36	23	factors	factor	NNS
cord-341690-h8fqijk5	36	24	including	include	VBG
cord-341690-h8fqijk5	36	25	epidermal	epidermal	JJ
cord-341690-h8fqijk5	36	26	growth	growth	NN
cord-341690-h8fqijk5	36	27	factor	factor	NN
cord-341690-h8fqijk5	36	28	(	(	-LRB-
cord-341690-h8fqijk5	36	29	EGF	EGF	NNP
cord-341690-h8fqijk5	36	30	)	)	-RRB-
cord-341690-h8fqijk5	36	31	,	,	,
cord-341690-h8fqijk5	36	32	transforming	transform	VBG
cord-341690-h8fqijk5	36	33	growth	growth	NN
cord-341690-h8fqijk5	36	34	factor	factor	NN
cord-341690-h8fqijk5	36	35	-	-	HYPH
cord-341690-h8fqijk5	36	36	α	α	NN
cord-341690-h8fqijk5	36	37	(	(	-LRB-
cord-341690-h8fqijk5	36	38	TGF	TGF	NNP
cord-341690-h8fqijk5	36	39	-	-	HYPH
cord-341690-h8fqijk5	36	40	α	α	NNP
cord-341690-h8fqijk5	36	41	)	)	-RRB-
cord-341690-h8fqijk5	36	42	,	,	,
cord-341690-h8fqijk5	36	43	and	and	CC
cord-341690-h8fqijk5	36	44	the	the	DT
cord-341690-h8fqijk5	36	45	neuregulins	neuregulin	NNS
cord-341690-h8fqijk5	36	46	.	.	.
cord-341690-h8fqijk5	37	1	It	-PRON-	PRP
cord-341690-h8fqijk5	37	2	also	also	RB
cord-341690-h8fqijk5	37	3	interacts	interact	VBZ
cord-341690-h8fqijk5	37	4	with	with	IN
cord-341690-h8fqijk5	37	5	three	three	CD
cord-341690-h8fqijk5	37	6	homologous	homologous	JJ
cord-341690-h8fqijk5	37	7	transmembrane	transmembrane	NN
cord-341690-h8fqijk5	37	8	proteins	protein	NNS
cord-341690-h8fqijk5	37	9	ErbB2	ErbB2	NNP
cord-341690-h8fqijk5	37	10	,	,	,
cord-341690-h8fqijk5	37	11	ErbB3	ErbB3	NNP
cord-341690-h8fqijk5	37	12	and	and	CC
cord-341690-h8fqijk5	37	13	ErbB4	ErbB4	NNP
cord-341690-h8fqijk5	37	14	[	[	-LRB-
cord-341690-h8fqijk5	37	15	13	13	CD
cord-341690-h8fqijk5	37	16	,	,	,
cord-341690-h8fqijk5	37	17	14	14	CD
cord-341690-h8fqijk5	37	18	]	]	-RRB-
cord-341690-h8fqijk5	37	19	.	.	.
cord-341690-h8fqijk5	38	1	The	the	DT
cord-341690-h8fqijk5	38	2	binding	binding	NN
cord-341690-h8fqijk5	38	3	of	of	IN
cord-341690-h8fqijk5	38	4	EGF	EGF	NNP
cord-341690-h8fqijk5	38	5	to	to	IN
cord-341690-h8fqijk5	38	6	its	-PRON-	PRP$
cord-341690-h8fqijk5	38	7	cell	cell	NN
cord-341690-h8fqijk5	38	8	surface	surface	NN
cord-341690-h8fqijk5	38	9	receptor	receptor	NN
cord-341690-h8fqijk5	38	10	activates	activate	VBZ
cord-341690-h8fqijk5	38	11	the	the	DT
cord-341690-h8fqijk5	38	12	receptor	receptor	NN
cord-341690-h8fqijk5	38	13	's	's	POS
cord-341690-h8fqijk5	38	14	intrinsic	intrinsic	JJ
cord-341690-h8fqijk5	38	15	tyrosine	tyrosine	NN
cord-341690-h8fqijk5	38	16	kinase	kinase	NN
cord-341690-h8fqijk5	38	17	and	and	CC
cord-341690-h8fqijk5	38	18	phosphorylates	phosphorylate	VBZ
cord-341690-h8fqijk5	38	19	the	the	DT
cord-341690-h8fqijk5	38	20	tyrosine	tyrosine	NN
cord-341690-h8fqijk5	38	21	at	at	IN
cord-341690-h8fqijk5	38	22	its	-PRON-	PRP$
cord-341690-h8fqijk5	38	23	C	c	NN
cord-341690-h8fqijk5	38	24	-	-	HYPH
cord-341690-h8fqijk5	38	25	terminus	terminus	NN
cord-341690-h8fqijk5	38	26	.	.	.
cord-341690-h8fqijk5	39	1	Phosphorylated	Phosphorylated	NNP
cord-341690-h8fqijk5	39	2	EGFR	EGFR	NNP
cord-341690-h8fqijk5	39	3	is	be	VBZ
cord-341690-h8fqijk5	39	4	essential	essential	JJ
cord-341690-h8fqijk5	39	5	for	for	IN
cord-341690-h8fqijk5	39	6	the	the	DT
cord-341690-h8fqijk5	39	7	activation	activation	NN
cord-341690-h8fqijk5	39	8	of	of	IN
cord-341690-h8fqijk5	39	9	Ras	Ras	NNP
cord-341690-h8fqijk5	39	10	GTPase	GTPase	NNP
cord-341690-h8fqijk5	39	11	and	and	CC
cord-341690-h8fqijk5	39	12	ERK	ERK	NNP
cord-341690-h8fqijk5	39	13	[	[	-LRB-
cord-341690-h8fqijk5	39	14	15	15	CD
cord-341690-h8fqijk5	39	15	]	]	-RRB-
cord-341690-h8fqijk5	39	16	.	.	.
cord-341690-h8fqijk5	40	1	EGFR	EGFR	NNP
cord-341690-h8fqijk5	40	2	can	can	MD
cord-341690-h8fqijk5	40	3	be	be	VB
cord-341690-h8fqijk5	40	4	activated	activate	VBN
cord-341690-h8fqijk5	40	5	by	by	IN
cord-341690-h8fqijk5	40	6	many	many	JJ
cord-341690-h8fqijk5	40	7	viruses	virus	NNS
cord-341690-h8fqijk5	40	8	,	,	,
cord-341690-h8fqijk5	40	9	including	include	VBG
cord-341690-h8fqijk5	40	10	influenza	influenza	NN
cord-341690-h8fqijk5	40	11	A	A	NNP
cord-341690-h8fqijk5	40	12	,	,	,
cord-341690-h8fqijk5	40	13	hepatitis	hepatitis	NN
cord-341690-h8fqijk5	40	14	C	C	NNP
cord-341690-h8fqijk5	40	15	(	(	-LRB-
cord-341690-h8fqijk5	40	16	HCV	HCV	NNP
cord-341690-h8fqijk5	40	17	)	)	-RRB-
cord-341690-h8fqijk5	40	18	,	,	,
cord-341690-h8fqijk5	40	19	Herpes	Herpes	NNP
cord-341690-h8fqijk5	40	20	simplex	simplex	NN
cord-341690-h8fqijk5	40	21	type	type	NN
cord-341690-h8fqijk5	40	22	1(HSV-1	1(hsv-1	CD
cord-341690-h8fqijk5	40	23	)	)	-RRB-
cord-341690-h8fqijk5	40	24	,	,	,
cord-341690-h8fqijk5	40	25	and	and	CC
cord-341690-h8fqijk5	40	26	human	human	JJ
cord-341690-h8fqijk5	40	27	cytomegalovirus	cytomegalovirus	NN
cord-341690-h8fqijk5	40	28	(	(	-LRB-
cord-341690-h8fqijk5	40	29	HCMV	HCMV	NNP
cord-341690-h8fqijk5	40	30	)	)	-RRB-
cord-341690-h8fqijk5	40	31	[	[	-LRB-
cord-341690-h8fqijk5	40	32	16	16	CD
cord-341690-h8fqijk5	40	33	]	]	-RRB-
cord-341690-h8fqijk5	40	34	[	[	-LRB-
cord-341690-h8fqijk5	40	35	17	17	CD
cord-341690-h8fqijk5	40	36	]	]	-RRB-
cord-341690-h8fqijk5	40	37	[	[	-LRB-
cord-341690-h8fqijk5	40	38	18	18	CD
cord-341690-h8fqijk5	40	39	]	]	-RRB-
cord-341690-h8fqijk5	40	40	[	[	-LRB-
cord-341690-h8fqijk5	40	41	19	19	CD
cord-341690-h8fqijk5	40	42	]	]	-RRB-
cord-341690-h8fqijk5	40	43	.	.	.
cord-341690-h8fqijk5	41	1	In	in	IN
cord-341690-h8fqijk5	41	2	this	this	DT
cord-341690-h8fqijk5	41	3	study	study	NN
cord-341690-h8fqijk5	41	4	,	,	,
cord-341690-h8fqijk5	41	5	we	-PRON-	PRP
cord-341690-h8fqijk5	41	6	found	find	VBD
cord-341690-h8fqijk5	41	7	that	that	IN
cord-341690-h8fqijk5	41	8	TGEV	TGEV	NNP
cord-341690-h8fqijk5	41	9	caused	cause	VBD
cord-341690-h8fqijk5	41	10	F	F	NNP
cord-341690-h8fqijk5	41	11	-	-	HYPH
cord-341690-h8fqijk5	41	12	actin	actin	JJ
cord-341690-h8fqijk5	41	13	rearrangement	rearrangement	NN
cord-341690-h8fqijk5	41	14	and	and	CC
cord-341690-h8fqijk5	41	15	membrane	membrane	NN
cord-341690-h8fqijk5	41	16	ruffling	ruffle	VBG
cord-341690-h8fqijk5	41	17	early	early	RB
cord-341690-h8fqijk5	41	18	in	in	IN
cord-341690-h8fqijk5	41	19	infection	infection	NN
cord-341690-h8fqijk5	41	20	.	.	.
cord-341690-h8fqijk5	42	1	The	the	DT
cord-341690-h8fqijk5	42	2	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	42	3	of	of	IN
cord-341690-h8fqijk5	42	4	the	the	DT
cord-341690-h8fqijk5	42	5	EGFR	EGFR	NNP
cord-341690-h8fqijk5	42	6	was	be	VBD
cord-341690-h8fqijk5	42	7	also	also	RB
cord-341690-h8fqijk5	42	8	detected	detect	VBN
cord-341690-h8fqijk5	42	9	early	early	RB
cord-341690-h8fqijk5	42	10	in	in	IN
cord-341690-h8fqijk5	42	11	infection	infection	NN
cord-341690-h8fqijk5	42	12	.	.	.
cord-341690-h8fqijk5	43	1	We	-PRON-	PRP
cord-341690-h8fqijk5	43	2	found	find	VBD
cord-341690-h8fqijk5	43	3	that	that	IN
cord-341690-h8fqijk5	43	4	TGEV	TGEV	NNP
cord-341690-h8fqijk5	43	5	acted	act	VBD
cord-341690-h8fqijk5	43	6	via	via	IN
cord-341690-h8fqijk5	43	7	the	the	DT
cord-341690-h8fqijk5	43	8	EGFR	EGFR	NNP
cord-341690-h8fqijk5	43	9	-	-	HYPH
cord-341690-h8fqijk5	43	10	PI3K	PI3K	NNP
cord-341690-h8fqijk5	43	11	-	-	HYPH
cord-341690-h8fqijk5	43	12	Rac1	Rac1	NNP
cord-341690-h8fqijk5	43	13	/	/	SYM
cord-341690-h8fqijk5	43	14	Cdc42-PAK	Cdc42-PAK	NNP
cord-341690-h8fqijk5	43	15	-	-	HYPH
cord-341690-h8fqijk5	43	16	LIMK	LIMK	NNP
cord-341690-h8fqijk5	43	17	signaling	signal	VBG
cord-341690-h8fqijk5	43	18	pathway	pathway	NN
cord-341690-h8fqijk5	43	19	to	to	TO
cord-341690-h8fqijk5	43	20	regulate	regulate	VB
cord-341690-h8fqijk5	43	21	the	the	DT
cord-341690-h8fqijk5	43	22	activity	activity	NN
cord-341690-h8fqijk5	43	23	of	of	IN
cord-341690-h8fqijk5	43	24	cofilin	cofilin	NN
cord-341690-h8fqijk5	43	25	and	and	CC
cord-341690-h8fqijk5	43	26	F	F	NNP
cord-341690-h8fqijk5	43	27	-	-	HYPH
cord-341690-h8fqijk5	43	28	actin	actin	NNP
cord-341690-h8fqijk5	43	29	arrangement	arrangement	NN
cord-341690-h8fqijk5	43	30	early	early	RB
cord-341690-h8fqijk5	43	31	in	in	IN
cord-341690-h8fqijk5	43	32	infection	infection	NN
cord-341690-h8fqijk5	43	33	,	,	,
cord-341690-h8fqijk5	43	34	and	and	CC
cord-341690-h8fqijk5	43	35	also	also	RB
cord-341690-h8fqijk5	43	36	demonstrated	demonstrate	VBD
cord-341690-h8fqijk5	43	37	that	that	IN
cord-341690-h8fqijk5	43	38	EGFR	EGFR	NNP
cord-341690-h8fqijk5	43	39	was	be	VBD
cord-341690-h8fqijk5	43	40	a	a	DT
cord-341690-h8fqijk5	43	41	promoter	promoter	NN
cord-341690-h8fqijk5	43	42	for	for	IN
cord-341690-h8fqijk5	43	43	TGEV	TGEV	NNP
cord-341690-h8fqijk5	43	44	entry	entry	NN
cord-341690-h8fqijk5	43	45	.	.	.
cord-341690-h8fqijk5	44	1	Actin	actin	NN
cord-341690-h8fqijk5	44	2	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	44	3	assembly/	assembly/	ADD
cord-341690-h8fqijk5	45	1	disassembly	disassembly	NNP
cord-341690-h8fqijk5	45	2	dynamics	dynamic	NNS
cord-341690-h8fqijk5	45	3	are	be	VBP
cord-341690-h8fqijk5	45	4	critical	critical	JJ
cord-341690-h8fqijk5	45	5	for	for	IN
cord-341690-h8fqijk5	45	6	many	many	JJ
cord-341690-h8fqijk5	45	7	endocytic	endocytic	JJ
cord-341690-h8fqijk5	45	8	pathways	pathway	NNS
cord-341690-h8fqijk5	45	9	[	[	-LRB-
cord-341690-h8fqijk5	45	10	20	20	CD
cord-341690-h8fqijk5	45	11	]	]	-RRB-
cord-341690-h8fqijk5	45	12	.	.	.
cord-341690-h8fqijk5	46	1	In	in	IN
cord-341690-h8fqijk5	46	2	order	order	NN
cord-341690-h8fqijk5	46	3	to	to	TO
cord-341690-h8fqijk5	46	4	explore	explore	VB
cord-341690-h8fqijk5	46	5	potential	potential	JJ
cord-341690-h8fqijk5	46	6	interactions	interaction	NNS
cord-341690-h8fqijk5	46	7	between	between	IN
cord-341690-h8fqijk5	46	8	TGEV	TGEV	NNP
cord-341690-h8fqijk5	46	9	and	and	CC
cord-341690-h8fqijk5	46	10	F	f	NN
cord-341690-h8fqijk5	46	11	-	-	HYPH
cord-341690-h8fqijk5	46	12	actin	actin	NNP
cord-341690-h8fqijk5	46	13	,	,	,
cord-341690-h8fqijk5	46	14	we	-PRON-	PRP
cord-341690-h8fqijk5	46	15	stained	stain	VBD
cord-341690-h8fqijk5	46	16	cells	cell	NNS
cord-341690-h8fqijk5	46	17	shortly	shortly	RB
cord-341690-h8fqijk5	46	18	after	after	IN
cord-341690-h8fqijk5	46	19	infection	infection	NN
cord-341690-h8fqijk5	46	20	with	with	IN
cord-341690-h8fqijk5	46	21	phalloidin	phalloidin	NNS
cord-341690-h8fqijk5	46	22	-	-	HYPH
cord-341690-h8fqijk5	46	23	TRITC	TRITC	NNP
cord-341690-h8fqijk5	46	24	and	and	CC
cord-341690-h8fqijk5	46	25	examined	examine	VBD
cord-341690-h8fqijk5	46	26	them	-PRON-	PRP
cord-341690-h8fqijk5	46	27	using	use	VBG
cord-341690-h8fqijk5	46	28	confocal	confocal	JJ
cord-341690-h8fqijk5	46	29	microscopy	microscopy	NNS
cord-341690-h8fqijk5	46	30	(	(	-LRB-
cord-341690-h8fqijk5	46	31	Figure	figure	NN
cord-341690-h8fqijk5	46	32	1A	1a	NN
cord-341690-h8fqijk5	46	33	)	)	-RRB-
cord-341690-h8fqijk5	46	34	.	.	.
cord-341690-h8fqijk5	47	1	At	at	IN
cord-341690-h8fqijk5	47	2	5	5	CD
cord-341690-h8fqijk5	47	3	min	min	NN
cord-341690-h8fqijk5	47	4	post	post	NN
cord-341690-h8fqijk5	47	5	-	-	NN
cord-341690-h8fqijk5	47	6	infection	infection	JJ
cord-341690-h8fqijk5	47	7	(	(	-LRB-
cord-341690-h8fqijk5	47	8	mpi	mpi	NNP
cord-341690-h8fqijk5	47	9	)	)	-RRB-
cord-341690-h8fqijk5	47	10	,	,	,
cord-341690-h8fqijk5	47	11	F	F	NNP
cord-341690-h8fqijk5	47	12	-	-	HYPH
cord-341690-h8fqijk5	47	13	actin	actin	NN
cord-341690-h8fqijk5	47	14	filaments	filament	NNS
cord-341690-h8fqijk5	47	15	were	be	VBD
cord-341690-h8fqijk5	47	16	observed	observe	VBN
cord-341690-h8fqijk5	47	17	close	close	RB
cord-341690-h8fqijk5	47	18	to	to	IN
cord-341690-h8fqijk5	47	19	the	the	DT
cord-341690-h8fqijk5	47	20	cell	cell	NN
cord-341690-h8fqijk5	47	21	plasma	plasma	NN
cord-341690-h8fqijk5	47	22	membrane	membrane	NN
cord-341690-h8fqijk5	47	23	,	,	,
cord-341690-h8fqijk5	47	24	and	and	CC
cord-341690-h8fqijk5	47	25	accumulated	accumulate	VBN
cord-341690-h8fqijk5	47	26	in	in	IN
cord-341690-h8fqijk5	47	27	this	this	DT
cord-341690-h8fqijk5	47	28	region	region	NN
cord-341690-h8fqijk5	47	29	as	as	IN
cord-341690-h8fqijk5	47	30	the	the	DT
cord-341690-h8fqijk5	47	31	experiment	experiment	NN
cord-341690-h8fqijk5	47	32	progressed	progress	VBD
cord-341690-h8fqijk5	47	33	.	.	.
cord-341690-h8fqijk5	48	1	At	at	IN
cord-341690-h8fqijk5	48	2	30	30	CD
cord-341690-h8fqijk5	48	3	mpi	mpi	NN
cord-341690-h8fqijk5	48	4	,	,	,
cord-341690-h8fqijk5	48	5	actin	actin	JJ
cord-341690-h8fqijk5	48	6	stress	stress	NN
cord-341690-h8fqijk5	48	7	fibers	fiber	NNS
cord-341690-h8fqijk5	48	8	had	have	VBD
cord-341690-h8fqijk5	48	9	became	become	VBN
cord-341690-h8fqijk5	48	10	noticeably	noticeably	RB
cord-341690-h8fqijk5	48	11	less	less	RBR
cord-341690-h8fqijk5	48	12	abundant	abundant	JJ
cord-341690-h8fqijk5	48	13	in	in	IN
cord-341690-h8fqijk5	48	14	the	the	DT
cord-341690-h8fqijk5	48	15	cytoplasm	cytoplasm	NN
cord-341690-h8fqijk5	48	16	.	.	.
cord-341690-h8fqijk5	49	1	At	at	IN
cord-341690-h8fqijk5	49	2	60	60	CD
cord-341690-h8fqijk5	49	3	mpi	mpi	NN
cord-341690-h8fqijk5	49	4	,	,	,
cord-341690-h8fqijk5	49	5	almost	almost	RB
cord-341690-h8fqijk5	49	6	all	all	DT
cord-341690-h8fqijk5	49	7	F	F	NNP
cord-341690-h8fqijk5	49	8	-	-	HYPH
cord-341690-h8fqijk5	49	9	actin	actin	NNP
cord-341690-h8fqijk5	49	10	was	be	VBD
cord-341690-h8fqijk5	49	11	at	at	IN
cord-341690-h8fqijk5	49	12	the	the	DT
cord-341690-h8fqijk5	49	13	cell	cell	NN
cord-341690-h8fqijk5	49	14	membrane	membrane	NN
cord-341690-h8fqijk5	49	15	.	.	.
cord-341690-h8fqijk5	50	1	Transmission	transmission	NN
cord-341690-h8fqijk5	50	2	electron	electron	NN
cord-341690-h8fqijk5	50	3	microscopy	microscopy	NN
cord-341690-h8fqijk5	50	4	(	(	-LRB-
cord-341690-h8fqijk5	50	5	TEM	TEM	NNP
cord-341690-h8fqijk5	50	6	)	)	-RRB-
cord-341690-h8fqijk5	50	7	confirmed	confirm	VBD
cord-341690-h8fqijk5	50	8	that	that	IN
cord-341690-h8fqijk5	50	9	F	F	NNP
cord-341690-h8fqijk5	50	10	-	-	HYPH
cord-341690-h8fqijk5	50	11	actin	actin	NNP
cord-341690-h8fqijk5	50	12	gathered	gather	VBD
cord-341690-h8fqijk5	50	13	underneath	underneath	IN
cord-341690-h8fqijk5	50	14	the	the	DT
cord-341690-h8fqijk5	50	15	plasma	plasma	NN
cord-341690-h8fqijk5	50	16	membrane	membrane	NN
cord-341690-h8fqijk5	50	17	,	,	,
cord-341690-h8fqijk5	50	18	the	the	DT
cord-341690-h8fqijk5	50	19	podosome	podosome	NNP
cord-341690-h8fqijk5	50	20	and	and	CC
cord-341690-h8fqijk5	50	21	lamellipodium	lamellipodium	NNP
cord-341690-h8fqijk5	50	22	were	be	VBD
cord-341690-h8fqijk5	50	23	also	also	RB
cord-341690-h8fqijk5	50	24	observed	observe	VBN
cord-341690-h8fqijk5	50	25	in	in	IN
cord-341690-h8fqijk5	50	26	the	the	DT
cord-341690-h8fqijk5	50	27	cell	cell	NN
cord-341690-h8fqijk5	50	28	membrane	membrane	NN
cord-341690-h8fqijk5	50	29	(	(	-LRB-
cord-341690-h8fqijk5	50	30	Indicated	indicate	VBN
cord-341690-h8fqijk5	50	31	by	by	IN
cord-341690-h8fqijk5	50	32	the	the	DT
cord-341690-h8fqijk5	50	33	white	white	JJ
cord-341690-h8fqijk5	50	34	arrows	arrow	NNS
cord-341690-h8fqijk5	50	35	)	)	-RRB-
cord-341690-h8fqijk5	51	1	(	(	-LRB-
cord-341690-h8fqijk5	51	2	Figure	figure	NN
cord-341690-h8fqijk5	51	3	  	  	_SP
cord-341690-h8fqijk5	51	4	1B	1b	CD
cord-341690-h8fqijk5	51	5	)	)	-RRB-
cord-341690-h8fqijk5	51	6	.	.	.
cord-341690-h8fqijk5	52	1	The	the	DT
cord-341690-h8fqijk5	52	2	relationship	relationship	NN
cord-341690-h8fqijk5	52	3	between	between	IN
cord-341690-h8fqijk5	52	4	TGEV	TGEV	NNP
cord-341690-h8fqijk5	52	5	particles	particle	NNS
cord-341690-h8fqijk5	52	6	and	and	CC
cord-341690-h8fqijk5	52	7	F	f	NN
cord-341690-h8fqijk5	52	8	-	-	HYPH
cord-341690-h8fqijk5	52	9	actin	actin	NNP
cord-341690-h8fqijk5	52	10	early	early	RB
cord-341690-h8fqijk5	52	11	in	in	IN
cord-341690-h8fqijk5	52	12	infection	infection	NN
cord-341690-h8fqijk5	52	13	were	be	VBD
cord-341690-h8fqijk5	52	14	further	further	RB
cord-341690-h8fqijk5	52	15	examined	examine	VBN
cord-341690-h8fqijk5	52	16	by	by	IN
cord-341690-h8fqijk5	52	17	confocal	confocal	JJ
cord-341690-h8fqijk5	52	18	fluorescence	fluorescence	NN
cord-341690-h8fqijk5	52	19	microscopy	microscopy	NNS
cord-341690-h8fqijk5	52	20	,	,	,
cord-341690-h8fqijk5	52	21	with	with	IN
cord-341690-h8fqijk5	52	22	infected	infected	JJ
cord-341690-h8fqijk5	52	23	cells	cell	NNS
cord-341690-h8fqijk5	52	24	stained	stain	VBN
cord-341690-h8fqijk5	52	25	using	use	VBG
cord-341690-h8fqijk5	52	26	phalloidin	phalloidin	NNS
cord-341690-h8fqijk5	52	27	-	-	HYPH
cord-341690-h8fqijk5	52	28	TRITC	TRITC	NNP
cord-341690-h8fqijk5	52	29	,	,	,
cord-341690-h8fqijk5	52	30	TGEV	TGEV	NNP
cord-341690-h8fqijk5	52	31	particles	particle	NNS
cord-341690-h8fqijk5	52	32	were	be	VBD
cord-341690-h8fqijk5	52	33	labeled	label	VBN
cord-341690-h8fqijk5	52	34	with	with	IN
cord-341690-h8fqijk5	52	35	fluorescent	fluorescent	JJ
cord-341690-h8fqijk5	52	36	probe	probe	NN
cord-341690-h8fqijk5	52	37	DyLight	DyLight	NNP
cord-341690-h8fqijk5	52	38	594	594	CD
cord-341690-h8fqijk5	52	39	(	(	-LRB-
cord-341690-h8fqijk5	52	40	Figure	figure	NN
cord-341690-h8fqijk5	52	41	1C	1c	NN
cord-341690-h8fqijk5	52	42	)	)	-RRB-
cord-341690-h8fqijk5	52	43	.	.	.
cord-341690-h8fqijk5	53	1	At	at	IN
cord-341690-h8fqijk5	53	2	30	30	CD
cord-341690-h8fqijk5	53	3	mpi	mpi	NN
cord-341690-h8fqijk5	53	4	,	,	,
cord-341690-h8fqijk5	53	5	F	F	NNP
cord-341690-h8fqijk5	53	6	-	-	HYPH
cord-341690-h8fqijk5	53	7	actin	actin	NNP
cord-341690-h8fqijk5	53	8	was	be	VBD
cord-341690-h8fqijk5	53	9	organized	organize	VBN
cord-341690-h8fqijk5	53	10	to	to	TO
cord-341690-h8fqijk5	53	11	produce	produce	VB
cord-341690-h8fqijk5	53	12	a	a	DT
cord-341690-h8fqijk5	53	13	range	range	NN
cord-341690-h8fqijk5	53	14	of	of	IN
cord-341690-h8fqijk5	53	15	cell	cell	NN
cord-341690-h8fqijk5	53	16	surface	surface	NN
cord-341690-h8fqijk5	53	17	protrusions	protrusion	NNS
cord-341690-h8fqijk5	53	18	(	(	-LRB-
cord-341690-h8fqijk5	53	19	red	red	JJ
cord-341690-h8fqijk5	53	20	arrows	arrow	NNS
cord-341690-h8fqijk5	53	21	)	)	-RRB-
cord-341690-h8fqijk5	53	22	,	,	,
cord-341690-h8fqijk5	53	23	TGEV	TGEV	NNP
cord-341690-h8fqijk5	53	24	particles	particle	NNS
cord-341690-h8fqijk5	53	25	had	have	VBD
cord-341690-h8fqijk5	53	26	internalized	internalize	VBN
cord-341690-h8fqijk5	53	27	into	into	IN
cord-341690-h8fqijk5	53	28	the	the	DT
cord-341690-h8fqijk5	53	29	cell	cell	NN
cord-341690-h8fqijk5	53	30	membrane	membrane	NN
cord-341690-h8fqijk5	53	31	and	and	CC
cord-341690-h8fqijk5	53	32	begun	begin	VBN
cord-341690-h8fqijk5	53	33	to	to	TO
cord-341690-h8fqijk5	53	34	enter	enter	VB
cord-341690-h8fqijk5	53	35	the	the	DT
cord-341690-h8fqijk5	53	36	cytoplasm	cytoplasm	NN
cord-341690-h8fqijk5	53	37	.	.	.
cord-341690-h8fqijk5	54	1	At	at	IN
cord-341690-h8fqijk5	54	2	60	60	CD
cord-341690-h8fqijk5	54	3	mpi	mpi	NNS
cord-341690-h8fqijk5	54	4	,	,	,
cord-341690-h8fqijk5	54	5	TGEV	TGEV	NNP
cord-341690-h8fqijk5	54	6	had	have	VBD
cord-341690-h8fqijk5	54	7	entered	enter	VBN
cord-341690-h8fqijk5	54	8	the	the	DT
cord-341690-h8fqijk5	54	9	cytoplasm	cytoplasm	NN
cord-341690-h8fqijk5	54	10	,	,	,
cord-341690-h8fqijk5	54	11	we	-PRON-	PRP
cord-341690-h8fqijk5	54	12	found	find	VBD
cord-341690-h8fqijk5	54	13	that	that	IN
cord-341690-h8fqijk5	54	14	F	f	NN
cord-341690-h8fqijk5	54	15	-	-	HYPH
cord-341690-h8fqijk5	54	16	actin	actin	NNP
cord-341690-h8fqijk5	54	17	surrounded	surround	VBD
cord-341690-h8fqijk5	54	18	the	the	DT
cord-341690-h8fqijk5	54	19	TGEV	TGEV	NNP
cord-341690-h8fqijk5	54	20	particles	particle	NNS
cord-341690-h8fqijk5	54	21	in	in	IN
cord-341690-h8fqijk5	54	22	spatial	spatial	JJ
cord-341690-h8fqijk5	54	23	,	,	,
cord-341690-h8fqijk5	54	24	part	part	NN
cord-341690-h8fqijk5	54	25	of	of	IN
cord-341690-h8fqijk5	54	26	the	the	DT
cord-341690-h8fqijk5	54	27	virus	virus	NN
cord-341690-h8fqijk5	54	28	co	co	NN
cord-341690-h8fqijk5	54	29	-	-	VBN
cord-341690-h8fqijk5	54	30	localized	localize	VBN
cord-341690-h8fqijk5	54	31	with	with	IN
cord-341690-h8fqijk5	54	32	the	the	DT
cord-341690-h8fqijk5	54	33	F	F	NNP
cord-341690-h8fqijk5	54	34	-	-	HYPH
cord-341690-h8fqijk5	54	35	actin	actin	NNP
cord-341690-h8fqijk5	54	36	(	(	-LRB-
cord-341690-h8fqijk5	54	37	yellow	yellow	JJ
cord-341690-h8fqijk5	54	38	)	)	-RRB-
cord-341690-h8fqijk5	54	39	(	(	-LRB-
cord-341690-h8fqijk5	54	40	white	white	JJ
cord-341690-h8fqijk5	54	41	arrows	arrow	NNS
cord-341690-h8fqijk5	54	42	)	)	-RRB-
cord-341690-h8fqijk5	54	43	.	.	.
cord-341690-h8fqijk5	55	1	These	these	DT
cord-341690-h8fqijk5	55	2	phenomena	phenomenon	NNS
cord-341690-h8fqijk5	55	3	were	be	VBD
cord-341690-h8fqijk5	55	4	also	also	RB
cord-341690-h8fqijk5	55	5	shown	show	VBN
cord-341690-h8fqijk5	55	6	in	in	IN
cord-341690-h8fqijk5	55	7	3D	3d	JJ
cord-341690-h8fqijk5	55	8	rendered	render	VBN
cord-341690-h8fqijk5	55	9	images	image	NNS
cord-341690-h8fqijk5	55	10	.	.	.
cord-341690-h8fqijk5	56	1	Together	together	RB
cord-341690-h8fqijk5	56	2	,	,	,
cord-341690-h8fqijk5	56	3	these	these	DT
cord-341690-h8fqijk5	56	4	results	result	NNS
cord-341690-h8fqijk5	56	5	suggest	suggest	VBP
cord-341690-h8fqijk5	56	6	that	that	IN
cord-341690-h8fqijk5	56	7	the	the	DT
cord-341690-h8fqijk5	56	8	process	process	NN
cord-341690-h8fqijk5	56	9	of	of	IN
cord-341690-h8fqijk5	56	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	56	11	infection	infection	NN
cord-341690-h8fqijk5	56	12	causes	cause	VBZ
cord-341690-h8fqijk5	56	13	F	F	NNP
cord-341690-h8fqijk5	56	14	-	-	HYPH
cord-341690-h8fqijk5	56	15	actin	actin	VBG
cord-341690-h8fqijk5	56	16	accumulation	accumulation	NN
cord-341690-h8fqijk5	56	17	around	around	IN
cord-341690-h8fqijk5	56	18	the	the	DT
cord-341690-h8fqijk5	56	19	cell	cell	NN
cord-341690-h8fqijk5	56	20	membrane	membrane	NN
cord-341690-h8fqijk5	56	21	,	,	,
cord-341690-h8fqijk5	56	22	possibly	possibly	RB
cord-341690-h8fqijk5	56	23	promoting	promote	VBG
cord-341690-h8fqijk5	56	24	viral	viral	JJ
cord-341690-h8fqijk5	56	25	binding	binding	NN
cord-341690-h8fqijk5	56	26	,	,	,
cord-341690-h8fqijk5	56	27	penetration	penetration	NN
cord-341690-h8fqijk5	56	28	and	and	CC
cord-341690-h8fqijk5	56	29	intracellular	intracellular	JJ
cord-341690-h8fqijk5	56	30	trafficking	trafficking	NN
cord-341690-h8fqijk5	56	31	.	.	.
cord-341690-h8fqijk5	57	1	To	to	TO
cord-341690-h8fqijk5	57	2	test	test	VB
cord-341690-h8fqijk5	57	3	these	these	DT
cord-341690-h8fqijk5	57	4	hypothesis	hypothesis	NN
cord-341690-h8fqijk5	57	5	,	,	,
cord-341690-h8fqijk5	57	6	IPEC	IPEC	NNP
cord-341690-h8fqijk5	57	7	-	-	HYPH
cord-341690-h8fqijk5	57	8	J2	j2	NN
cord-341690-h8fqijk5	57	9	cells	cell	NNS
cord-341690-h8fqijk5	57	10	were	be	VBD
cord-341690-h8fqijk5	57	11	pretreated	pretreate	VBN
cord-341690-h8fqijk5	57	12	with	with	IN
cord-341690-h8fqijk5	57	13	three	three	CD
cord-341690-h8fqijk5	57	14	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	57	15	inhibitors	inhibitor	NNS
cord-341690-h8fqijk5	57	16	:	:	:
cord-341690-h8fqijk5	58	1	Latrunculin	Latrunculin	NNP
cord-341690-h8fqijk5	58	2	A	A	NNP
cord-341690-h8fqijk5	58	3	(	(	-LRB-
cord-341690-h8fqijk5	58	4	Lat	Lat	NNP
cord-341690-h8fqijk5	58	5	A	A	NNP
cord-341690-h8fqijk5	58	6	)	)	-RRB-
cord-341690-h8fqijk5	58	7	,	,	,
cord-341690-h8fqijk5	58	8	Cytochalasin	Cytochalasin	NNP
cord-341690-h8fqijk5	58	9	D	D	NNP
cord-341690-h8fqijk5	58	10	(	(	-LRB-
cord-341690-h8fqijk5	58	11	Cyto	Cyto	NNP
cord-341690-h8fqijk5	58	12	D	D	NNP
cord-341690-h8fqijk5	58	13	)	)	-RRB-
cord-341690-h8fqijk5	58	14	,	,	,
cord-341690-h8fqijk5	58	15	and	and	CC
cord-341690-h8fqijk5	58	16	Cucurbitacin	Cucurbitacin	NNP
cord-341690-h8fqijk5	58	17	E	E	NNP
cord-341690-h8fqijk5	58	18	(	(	-LRB-
cord-341690-h8fqijk5	58	19	Cu	Cu	NNP
cord-341690-h8fqijk5	58	20	E	e	NN
cord-341690-h8fqijk5	58	21	)	)	-RRB-
cord-341690-h8fqijk5	58	22	at	at	IN
cord-341690-h8fqijk5	58	23	37	37	CD
cord-341690-h8fqijk5	58	24	°	°	NN
cord-341690-h8fqijk5	58	25	C	c	NN
cord-341690-h8fqijk5	58	26	for	for	IN
cord-341690-h8fqijk5	58	27	1h	1h	CD
cord-341690-h8fqijk5	58	28	.	.	.
cord-341690-h8fqijk5	59	1	The	the	DT
cord-341690-h8fqijk5	59	2	effect	effect	NN
cord-341690-h8fqijk5	59	3	of	of	IN
cord-341690-h8fqijk5	59	4	these	these	DT
cord-341690-h8fqijk5	59	5	inhibitors	inhibitor	NNS
cord-341690-h8fqijk5	59	6	on	on	IN
cord-341690-h8fqijk5	59	7	cell	cell	NN
cord-341690-h8fqijk5	59	8	viability	viability	NN
cord-341690-h8fqijk5	59	9	was	be	VBD
cord-341690-h8fqijk5	59	10	shown	show	VBN
cord-341690-h8fqijk5	59	11	in	in	IN
cord-341690-h8fqijk5	59	12	Figure	Figure	NNP
cord-341690-h8fqijk5	59	13	S1	S1	NNP
cord-341690-h8fqijk5	59	14	.	.	.
cord-341690-h8fqijk5	60	1	All	all	DT
cord-341690-h8fqijk5	60	2	three	three	CD
cord-341690-h8fqijk5	60	3	inhibitors	inhibitor	NNS
cord-341690-h8fqijk5	60	4	reduced	reduce	VBD
cord-341690-h8fqijk5	60	5	TGEV	TGEV	NNP
cord-341690-h8fqijk5	60	6	entry	entry	NN
cord-341690-h8fqijk5	60	7	in	in	IN
cord-341690-h8fqijk5	60	8	a	a	DT
cord-341690-h8fqijk5	60	9	dose	dose	NN
cord-341690-h8fqijk5	60	10	dependent	dependent	JJ
cord-341690-h8fqijk5	60	11	manner	manner	NN
cord-341690-h8fqijk5	60	12	compared	compare	VBN
cord-341690-h8fqijk5	60	13	with	with	IN
cord-341690-h8fqijk5	60	14	mock	mock	JJ
cord-341690-h8fqijk5	60	15	control	control	NN
cord-341690-h8fqijk5	60	16	cells	cell	NNS
cord-341690-h8fqijk5	60	17	(	(	-LRB-
cord-341690-h8fqijk5	60	18	Figure	figure	NN
cord-341690-h8fqijk5	60	19	1D	1d	CD
cord-341690-h8fqijk5	60	20	,	,	,
cord-341690-h8fqijk5	60	21	1E	1E	NNP
cord-341690-h8fqijk5	60	22	,	,	,
cord-341690-h8fqijk5	60	23	1F	1F	NNP
cord-341690-h8fqijk5	60	24	)	)	-RRB-
cord-341690-h8fqijk5	60	25	.	.	.
cord-341690-h8fqijk5	61	1	These	these	DT
cord-341690-h8fqijk5	61	2	results	result	NNS
cord-341690-h8fqijk5	61	3	provide	provide	VBP
cord-341690-h8fqijk5	61	4	evidence	evidence	NN
cord-341690-h8fqijk5	61	5	that	that	IN
cord-341690-h8fqijk5	61	6	F	f	NN
cord-341690-h8fqijk5	61	7	-	-	HYPH
cord-341690-h8fqijk5	61	8	actin	actin	NNP
cord-341690-h8fqijk5	61	9	is	be	VBZ
cord-341690-h8fqijk5	61	10	involved	involve	VBN
cord-341690-h8fqijk5	61	11	in	in	IN
cord-341690-h8fqijk5	61	12	the	the	DT
cord-341690-h8fqijk5	61	13	TGEV	TGEV	NNP
cord-341690-h8fqijk5	61	14	entry	entry	NN
cord-341690-h8fqijk5	61	15	process	process	NN
cord-341690-h8fqijk5	61	16	.	.	.
cord-341690-h8fqijk5	62	1	To	to	TO
cord-341690-h8fqijk5	62	2	investigate	investigate	VB
cord-341690-h8fqijk5	62	3	the	the	DT
cord-341690-h8fqijk5	62	4	relationship	relationship	NN
cord-341690-h8fqijk5	62	5	between	between	IN
cord-341690-h8fqijk5	62	6	cofilin	cofilin	NN
cord-341690-h8fqijk5	62	7	and	and	CC
cord-341690-h8fqijk5	62	8	TGEV	TGEV	NNP
cord-341690-h8fqijk5	62	9	infection	infection	NN
cord-341690-h8fqijk5	62	10	,	,	,
cord-341690-h8fqijk5	62	11	we	-PRON-	PRP
cord-341690-h8fqijk5	62	12	measured	measure	VBD
cord-341690-h8fqijk5	62	13	the	the	DT
cord-341690-h8fqijk5	62	14	levels	level	NNS
cord-341690-h8fqijk5	62	15	of	of	IN
cord-341690-h8fqijk5	62	16	p	p	NN
cord-341690-h8fqijk5	62	17	-	-	:
cord-341690-h8fqijk5	62	18	cofilin	cofilin	NN
cord-341690-h8fqijk5	62	19	and	and	CC
cord-341690-h8fqijk5	62	20	cofilin	cofilin	NN
cord-341690-h8fqijk5	62	21	in	in	IN
cord-341690-h8fqijk5	62	22	infected	infected	JJ
cord-341690-h8fqijk5	62	23	and	and	CC
cord-341690-h8fqijk5	62	24	uninfected	uninfected	JJ
cord-341690-h8fqijk5	62	25	cells	cell	NNS
cord-341690-h8fqijk5	62	26	by	by	IN
cord-341690-h8fqijk5	62	27	Western	western	JJ
cord-341690-h8fqijk5	62	28	blot	blot	NN
cord-341690-h8fqijk5	62	29	(	(	-LRB-
cord-341690-h8fqijk5	62	30	Figure	figure	NN
cord-341690-h8fqijk5	62	31	1	1	CD
cord-341690-h8fqijk5	62	32	G	g	NN
cord-341690-h8fqijk5	62	33	,	,	,
cord-341690-h8fqijk5	62	34	1H	1h	CD
cord-341690-h8fqijk5	62	35	,	,	,
cord-341690-h8fqijk5	62	36	1I	1i	CD
cord-341690-h8fqijk5	62	37	,	,	,
cord-341690-h8fqijk5	62	38	1J	1j	CD
cord-341690-h8fqijk5	62	39	)	)	-RRB-
cord-341690-h8fqijk5	62	40	.	.	.
cord-341690-h8fqijk5	63	1	In	in	IN
cord-341690-h8fqijk5	63	2	TGEV	TGEV	NNP
cord-341690-h8fqijk5	63	3	-	-	HYPH
cord-341690-h8fqijk5	63	4	infected	infect	VBN
cord-341690-h8fqijk5	63	5	cells	cell	NNS
cord-341690-h8fqijk5	63	6	,	,	,
cord-341690-h8fqijk5	63	7	the	the	DT
cord-341690-h8fqijk5	63	8	level	level	NN
cord-341690-h8fqijk5	63	9	of	of	IN
cord-341690-h8fqijk5	63	10	p	p	NN
cord-341690-h8fqijk5	63	11	-	-	HYPH
cord-341690-h8fqijk5	63	12	cofilin	cofilin	NN
cord-341690-h8fqijk5	63	13	increased	increase	VBD
cord-341690-h8fqijk5	63	14	from	from	IN
cord-341690-h8fqijk5	63	15	1	1	CD
cord-341690-h8fqijk5	63	16	mpi	mpi	NNP
cord-341690-h8fqijk5	63	17	to	to	IN
cord-341690-h8fqijk5	63	18	30	30	CD
cord-341690-h8fqijk5	63	19	mpi	mpi	NN
cord-341690-h8fqijk5	63	20	and	and	CC
cord-341690-h8fqijk5	63	21	decreased	decrease	VBD
cord-341690-h8fqijk5	63	22	at	at	IN
cord-341690-h8fqijk5	63	23	60	60	CD
cord-341690-h8fqijk5	63	24	mpi	mpi	NN
cord-341690-h8fqijk5	63	25	,	,	,
cord-341690-h8fqijk5	63	26	but	but	CC
cord-341690-h8fqijk5	63	27	the	the	DT
cord-341690-h8fqijk5	63	28	level	level	NN
cord-341690-h8fqijk5	63	29	of	of	IN
cord-341690-h8fqijk5	63	30	cofilin	cofilin	NN
cord-341690-h8fqijk5	63	31	was	be	VBD
cord-341690-h8fqijk5	63	32	low	low	JJ
cord-341690-h8fqijk5	63	33	from	from	IN
cord-341690-h8fqijk5	63	34	1	1	CD
cord-341690-h8fqijk5	63	35	mpi	mpi	NNP
cord-341690-h8fqijk5	63	36	to	to	IN
cord-341690-h8fqijk5	63	37	30	30	CD
cord-341690-h8fqijk5	63	38	mpi	mpi	NN
cord-341690-h8fqijk5	63	39	and	and	CC
cord-341690-h8fqijk5	63	40	increased	increase	VBD
cord-341690-h8fqijk5	63	41	at	at	IN
cord-341690-h8fqijk5	63	42	60	60	CD
cord-341690-h8fqijk5	63	43	mpi	mpi	NN
cord-341690-h8fqijk5	63	44	.	.	.
cord-341690-h8fqijk5	64	1	In	in	IN
cord-341690-h8fqijk5	64	2	uninfected	uninfected	JJ
cord-341690-h8fqijk5	64	3	cells	cell	NNS
cord-341690-h8fqijk5	64	4	,	,	,
cord-341690-h8fqijk5	64	5	the	the	DT
cord-341690-h8fqijk5	64	6	level	level	NN
cord-341690-h8fqijk5	64	7	of	of	IN
cord-341690-h8fqijk5	64	8	p	p	NN
cord-341690-h8fqijk5	64	9	-	-	:
cord-341690-h8fqijk5	64	10	cofilin	cofilin	NN
cord-341690-h8fqijk5	64	11	was	be	VBD
cord-341690-h8fqijk5	64	12	low	low	JJ
cord-341690-h8fqijk5	64	13	from	from	IN
cord-341690-h8fqijk5	64	14	1mpi	1mpi	CD
cord-341690-h8fqijk5	64	15	to	to	IN
cord-341690-h8fqijk5	64	16	60	60	CD
cord-341690-h8fqijk5	64	17	mpi	mpi	NN
cord-341690-h8fqijk5	64	18	and	and	CC
cord-341690-h8fqijk5	64	19	increased	increase	VBD
cord-341690-h8fqijk5	64	20	at	at	IN
cord-341690-h8fqijk5	64	21	120	120	CD
cord-341690-h8fqijk5	64	22	mpi	mpi	NNP
cord-341690-h8fqijk5	64	23	,	,	,
cord-341690-h8fqijk5	64	24	but	but	CC
cord-341690-h8fqijk5	64	25	the	the	DT
cord-341690-h8fqijk5	64	26	level	level	NN
cord-341690-h8fqijk5	64	27	of	of	IN
cord-341690-h8fqijk5	64	28	cofilin	cofilin	NN
cord-341690-h8fqijk5	64	29	maintained	maintain	VBD
cord-341690-h8fqijk5	64	30	a	a	DT
cord-341690-h8fqijk5	64	31	high	high	JJ
cord-341690-h8fqijk5	64	32	expression	expression	NN
cord-341690-h8fqijk5	64	33	level	level	NN
cord-341690-h8fqijk5	64	34	from	from	IN
cord-341690-h8fqijk5	64	35	5mpi	5mpi	CD
cord-341690-h8fqijk5	64	36	to	to	IN
cord-341690-h8fqijk5	64	37	60	60	CD
cord-341690-h8fqijk5	64	38	mpi	mpi	NN
cord-341690-h8fqijk5	64	39	.	.	.
cord-341690-h8fqijk5	65	1	We	-PRON-	PRP
cord-341690-h8fqijk5	65	2	hypothesize	hypothesize	VBP
cord-341690-h8fqijk5	65	3	that	that	IN
cord-341690-h8fqijk5	65	4	the	the	DT
cord-341690-h8fqijk5	65	5	process	process	NN
cord-341690-h8fqijk5	65	6	by	by	IN
cord-341690-h8fqijk5	65	7	which	which	WDT
cord-341690-h8fqijk5	65	8	TGEV	TGEV	NNP
cord-341690-h8fqijk5	65	9	causes	cause	VBZ
cord-341690-h8fqijk5	65	10	F	F	NNP
cord-341690-h8fqijk5	65	11	-	-	HYPH
cord-341690-h8fqijk5	65	12	actin	actin	JJ
cord-341690-h8fqijk5	65	13	filaments	filament	NNS
cord-341690-h8fqijk5	65	14	to	to	TO
cord-341690-h8fqijk5	65	15	gather	gather	VB
cord-341690-h8fqijk5	65	16	around	around	IN
cord-341690-h8fqijk5	65	17	the	the	DT
cord-341690-h8fqijk5	65	18	cell	cell	NN
cord-341690-h8fqijk5	65	19	membrane	membrane	NN
cord-341690-h8fqijk5	65	20	and	and	CC
cord-341690-h8fqijk5	65	21	the	the	DT
cord-341690-h8fqijk5	65	22	formation	formation	NN
cord-341690-h8fqijk5	65	23	of	of	IN
cord-341690-h8fqijk5	65	24	cell	cell	NN
cord-341690-h8fqijk5	65	25	surface	surface	NN
cord-341690-h8fqijk5	65	26	protrusions	protrusion	NNS
cord-341690-h8fqijk5	65	27	require	require	VBP
cord-341690-h8fqijk5	65	28	the	the	DT
cord-341690-h8fqijk5	65	29	participation	participation	NN
cord-341690-h8fqijk5	65	30	of	of	IN
cord-341690-h8fqijk5	65	31	p	p	NN
cord-341690-h8fqijk5	65	32	-	-	NN
cord-341690-h8fqijk5	65	33	cofilin	cofilin	NN
cord-341690-h8fqijk5	65	34	.	.	.
cord-341690-h8fqijk5	66	1	To	to	TO
cord-341690-h8fqijk5	66	2	examine	examine	VB
cord-341690-h8fqijk5	66	3	the	the	DT
cord-341690-h8fqijk5	66	4	role	role	NN
cord-341690-h8fqijk5	66	5	of	of	IN
cord-341690-h8fqijk5	66	6	cofilin	cofilin	NNP
cord-341690-h8fqijk5	66	7	more	more	RBR
cord-341690-h8fqijk5	66	8	closely	closely	RB
cord-341690-h8fqijk5	66	9	,	,	,
cord-341690-h8fqijk5	66	10	we	-PRON-	PRP
cord-341690-h8fqijk5	66	11	conducted	conduct	VBD
cord-341690-h8fqijk5	66	12	series	series	NN
cord-341690-h8fqijk5	66	13	of	of	IN
cord-341690-h8fqijk5	66	14	experiments	experiment	NNS
cord-341690-h8fqijk5	66	15	in	in	IN
cord-341690-h8fqijk5	66	16	which	which	WDT
cord-341690-h8fqijk5	66	17	cofilin	cofilin	NN
cord-341690-h8fqijk5	66	18	distribution	distribution	NN
cord-341690-h8fqijk5	66	19	and	and	CC
cord-341690-h8fqijk5	66	20	function	function	NN
cord-341690-h8fqijk5	66	21	were	be	VBD
cord-341690-h8fqijk5	66	22	assessed	assess	VBN
cord-341690-h8fqijk5	66	23	in	in	IN
cord-341690-h8fqijk5	66	24	uninfected	uninfected	JJ
cord-341690-h8fqijk5	66	25	and	and	CC
cord-341690-h8fqijk5	66	26	TGEV	TGEV	NNP
cord-341690-h8fqijk5	66	27	-	-	HYPH
cord-341690-h8fqijk5	66	28	infected	infect	VBN
cord-341690-h8fqijk5	66	29	cells	cell	NNS
cord-341690-h8fqijk5	66	30	.	.	.
cord-341690-h8fqijk5	67	1	Most	Most	JJS
cord-341690-h8fqijk5	67	2	p	p	NN
cord-341690-h8fqijk5	67	3	-	-	:
cord-341690-h8fqijk5	67	4	cofilin	cofilin	NNP
cord-341690-h8fqijk5	67	5	was	be	VBD
cord-341690-h8fqijk5	67	6	found	find	VBN
cord-341690-h8fqijk5	67	7	in	in	IN
cord-341690-h8fqijk5	67	8	the	the	DT
cord-341690-h8fqijk5	67	9	nucleus	nucleus	NN
cord-341690-h8fqijk5	67	10	of	of	IN
cord-341690-h8fqijk5	67	11	uninfected	uninfected	JJ
cord-341690-h8fqijk5	67	12	cells	cell	NNS
cord-341690-h8fqijk5	67	13	(	(	-LRB-
cord-341690-h8fqijk5	67	14	Figure	figure	NN
cord-341690-h8fqijk5	67	15	2A	2a	CD
cord-341690-h8fqijk5	67	16	)	)	-RRB-
cord-341690-h8fqijk5	67	17	.	.	.
cord-341690-h8fqijk5	68	1	In	in	IN
cord-341690-h8fqijk5	68	2	contrast	contrast	NN
cord-341690-h8fqijk5	68	3	,	,	,
cord-341690-h8fqijk5	68	4	early	early	RB
cord-341690-h8fqijk5	68	5	in	in	IN
cord-341690-h8fqijk5	68	6	TGEV	TGEV	NNP
cord-341690-h8fqijk5	68	7	infection	infection	NN
cord-341690-h8fqijk5	68	8	,	,	,
cord-341690-h8fqijk5	68	9	p	p	NN
cord-341690-h8fqijk5	68	10	-	-	HYPH
cord-341690-h8fqijk5	68	11	cofilin	cofilin	NN
cord-341690-h8fqijk5	68	12	redistributed	redistribute	VBD
cord-341690-h8fqijk5	68	13	to	to	IN
cord-341690-h8fqijk5	68	14	the	the	DT
cord-341690-h8fqijk5	68	15	cytoplasm	cytoplasm	NN
cord-341690-h8fqijk5	68	16	and	and	CC
cord-341690-h8fqijk5	68	17	was	be	VBD
cord-341690-h8fqijk5	68	18	less	less	RBR
cord-341690-h8fqijk5	68	19	abundant	abundant	JJ
cord-341690-h8fqijk5	68	20	in	in	IN
cord-341690-h8fqijk5	68	21	the	the	DT
cord-341690-h8fqijk5	68	22	nucleus	nucleus	NN
cord-341690-h8fqijk5	68	23	.	.	.
cord-341690-h8fqijk5	69	1	However	however	RB
cord-341690-h8fqijk5	69	2	,	,	,
cord-341690-h8fqijk5	69	3	at	at	IN
cord-341690-h8fqijk5	69	4	60	60	CD
cord-341690-h8fqijk5	69	5	mpi	mpi	NN
cord-341690-h8fqijk5	69	6	,	,	,
cord-341690-h8fqijk5	69	7	p	p	NN
cord-341690-h8fqijk5	69	8	-	-	:
cord-341690-h8fqijk5	69	9	cofilin	cofilin	NNP
cord-341690-h8fqijk5	69	10	appeared	appear	VBD
cord-341690-h8fqijk5	69	11	to	to	TO
cord-341690-h8fqijk5	69	12	shift	shift	VB
cord-341690-h8fqijk5	69	13	from	from	IN
cord-341690-h8fqijk5	69	14	the	the	DT
cord-341690-h8fqijk5	69	15	cytoplasm	cytoplasm	NN
cord-341690-h8fqijk5	69	16	back	back	RB
cord-341690-h8fqijk5	69	17	to	to	IN
cord-341690-h8fqijk5	69	18	the	the	DT
cord-341690-h8fqijk5	69	19	nucleus	nucleus	NN
cord-341690-h8fqijk5	69	20	(	(	-LRB-
cord-341690-h8fqijk5	69	21	Figure	figure	NN
cord-341690-h8fqijk5	69	22	2A	2a	CD
cord-341690-h8fqijk5	69	23	)	)	-RRB-
cord-341690-h8fqijk5	69	24	.	.	.
cord-341690-h8fqijk5	70	1	When	when	WRB
cord-341690-h8fqijk5	70	2	the	the	DT
cord-341690-h8fqijk5	70	3	distribution	distribution	NN
cord-341690-h8fqijk5	70	4	of	of	IN
cord-341690-h8fqijk5	70	5	p	p	NN
cord-341690-h8fqijk5	70	6	-	-	:
cord-341690-h8fqijk5	70	7	cofilin	cofilin	NN
cord-341690-h8fqijk5	70	8	and	and	CC
cord-341690-h8fqijk5	70	9	F	F	NNP
cord-341690-h8fqijk5	70	10	-	-	HYPH
cord-341690-h8fqijk5	70	11	actin	actin	NNP
cord-341690-h8fqijk5	70	12	were	be	VBD
cord-341690-h8fqijk5	70	13	observed	observe	VBN
cord-341690-h8fqijk5	70	14	early	early	RB
cord-341690-h8fqijk5	70	15	in	in	IN
cord-341690-h8fqijk5	70	16	infection	infection	NN
cord-341690-h8fqijk5	70	17	,	,	,
cord-341690-h8fqijk5	70	18	we	-PRON-	PRP
cord-341690-h8fqijk5	70	19	found	find	VBD
cord-341690-h8fqijk5	70	20	most	most	JJS
cord-341690-h8fqijk5	70	21	p	p	NN
cord-341690-h8fqijk5	70	22	-	-	:
cord-341690-h8fqijk5	70	23	cofilin	cofilin	NNP
cord-341690-h8fqijk5	70	24	did	do	VBD
cord-341690-h8fqijk5	70	25	not	not	RB
cord-341690-h8fqijk5	70	26	colocalize	colocalize	VB
cord-341690-h8fqijk5	70	27	with	with	IN
cord-341690-h8fqijk5	70	28	F	F	NNP
cord-341690-h8fqijk5	70	29	-	-	HYPH
cord-341690-h8fqijk5	70	30	actin	actin	NNP
cord-341690-h8fqijk5	70	31	,	,	,
cord-341690-h8fqijk5	70	32	and	and	CC
cord-341690-h8fqijk5	70	33	multiple	multiple	JJ
cord-341690-h8fqijk5	70	34	protrusions	protrusion	NNS
cord-341690-h8fqijk5	70	35	were	be	VBD
cord-341690-h8fqijk5	70	36	noted	note	VBN
cord-341690-h8fqijk5	70	37	around	around	IN
cord-341690-h8fqijk5	70	38	the	the	DT
cord-341690-h8fqijk5	70	39	cell	cell	NN
cord-341690-h8fqijk5	70	40	membrance	membrance	NN
cord-341690-h8fqijk5	70	41	(	(	-LRB-
cord-341690-h8fqijk5	70	42	Figure	figure	NN
cord-341690-h8fqijk5	70	43	2B	2b	CD
cord-341690-h8fqijk5	70	44	)	)	-RRB-
cord-341690-h8fqijk5	70	45	.	.	.
cord-341690-h8fqijk5	71	1	We	-PRON-	PRP
cord-341690-h8fqijk5	71	2	knocked	knock	VBD
cord-341690-h8fqijk5	71	3	cofilin	cofilin	NN
cord-341690-h8fqijk5	71	4	down	down	RP
cord-341690-h8fqijk5	71	5	in	in	IN
cord-341690-h8fqijk5	71	6	normal	normal	JJ
cord-341690-h8fqijk5	71	7	IPEC	IPEC	NNP
cord-341690-h8fqijk5	71	8	-	-	HYPH
cord-341690-h8fqijk5	71	9	J2	j2	NN
cord-341690-h8fqijk5	71	10	cells	cell	NNS
cord-341690-h8fqijk5	71	11	,	,	,
cord-341690-h8fqijk5	71	12	and	and	CC
cord-341690-h8fqijk5	71	13	found	find	VBD
cord-341690-h8fqijk5	71	14	that	that	IN
cord-341690-h8fqijk5	71	15	the	the	DT
cord-341690-h8fqijk5	71	16	actin	actin	NN
cord-341690-h8fqijk5	71	17	stress	stress	NN
cord-341690-h8fqijk5	71	18	fibers	fiber	NNS
cord-341690-h8fqijk5	71	19	were	be	VBD
cord-341690-h8fqijk5	71	20	also	also	RB
cord-341690-h8fqijk5	71	21	in	in	IN
cord-341690-h8fqijk5	71	22	the	the	DT
cord-341690-h8fqijk5	71	23	cytoplasm	cytoplasm	NN
cord-341690-h8fqijk5	71	24	.	.	.
cord-341690-h8fqijk5	72	1	Usually	usually	RB
cord-341690-h8fqijk5	72	2	underneath	underneath	IN
cord-341690-h8fqijk5	72	3	the	the	DT
cord-341690-h8fqijk5	72	4	cell	cell	NN
cord-341690-h8fqijk5	72	5	membrane	membrane	NN
cord-341690-h8fqijk5	72	6	are	be	VBP
cord-341690-h8fqijk5	72	7	the	the	DT
cord-341690-h8fqijk5	72	8	loosely	loosely	RB
cord-341690-h8fqijk5	72	9	organized	organize	VBN
cord-341690-h8fqijk5	72	10	network	network	NN
cord-341690-h8fqijk5	72	11	of	of	IN
cord-341690-h8fqijk5	72	12	F	F	NNP
cord-341690-h8fqijk5	72	13	-	-	HYPH
cord-341690-h8fqijk5	72	14	actin	actin	JJ
cord-341690-h8fqijk5	72	15	filaments	filament	NNS
cord-341690-h8fqijk5	72	16	that	that	WDT
cord-341690-h8fqijk5	72	17	are	be	VBP
cord-341690-h8fqijk5	72	18	termed	term	VBN
cord-341690-h8fqijk5	72	19	cortical	cortical	JJ
cord-341690-h8fqijk5	72	20	actin	actin	NN
cord-341690-h8fqijk5	72	21	[	[	-LRB-
cord-341690-h8fqijk5	72	22	4	4	CD
cord-341690-h8fqijk5	72	23	]	]	-RRB-
cord-341690-h8fqijk5	72	24	,	,	,
cord-341690-h8fqijk5	72	25	but	but	CC
cord-341690-h8fqijk5	72	26	the	the	DT
cord-341690-h8fqijk5	72	27	cortical	cortical	JJ
cord-341690-h8fqijk5	72	28	actin	actin	NN
cord-341690-h8fqijk5	72	29	underneath	underneath	IN
cord-341690-h8fqijk5	72	30	the	the	DT
cord-341690-h8fqijk5	72	31	cell	cell	NN
cord-341690-h8fqijk5	72	32	membrane	membrane	NN
cord-341690-h8fqijk5	72	33	gathered	gather	VBD
cord-341690-h8fqijk5	72	34	together	together	RB
cord-341690-h8fqijk5	72	35	,	,	,
cord-341690-h8fqijk5	72	36	the	the	DT
cord-341690-h8fqijk5	72	37	cell	cell	NN
cord-341690-h8fqijk5	72	38	surface	surface	NN
cord-341690-h8fqijk5	72	39	was	be	VBD
cord-341690-h8fqijk5	72	40	smooth	smooth	JJ
cord-341690-h8fqijk5	72	41	and	and	CC
cord-341690-h8fqijk5	72	42	could	could	MD
cord-341690-h8fqijk5	72	43	n't	not	RB
cord-341690-h8fqijk5	72	44	form	form	VB
cord-341690-h8fqijk5	72	45	protrusions	protrusion	NNS
cord-341690-h8fqijk5	72	46	.	.	.
cord-341690-h8fqijk5	73	1	In	in	IN
cord-341690-h8fqijk5	73	2	cofilin	cofilin	JJ
cord-341690-h8fqijk5	73	3	knockdown	knockdown	NN
cord-341690-h8fqijk5	73	4	cells	cell	NNS
cord-341690-h8fqijk5	73	5	,	,	,
cord-341690-h8fqijk5	73	6	early	early	RB
cord-341690-h8fqijk5	73	7	in	in	IN
cord-341690-h8fqijk5	73	8	TGEV	tgev	NN
cord-341690-h8fqijk5	73	9	-	-	HYPH
cord-341690-h8fqijk5	73	10	infection	infection	NN
cord-341690-h8fqijk5	73	11	,	,	,
cord-341690-h8fqijk5	73	12	some	some	DT
cord-341690-h8fqijk5	73	13	actin	actin	NN
cord-341690-h8fqijk5	73	14	stress	stress	NN
cord-341690-h8fqijk5	73	15	fibers	fiber	NNS
cord-341690-h8fqijk5	73	16	were	be	VBD
cord-341690-h8fqijk5	73	17	also	also	RB
cord-341690-h8fqijk5	73	18	found	find	VBN
cord-341690-h8fqijk5	73	19	in	in	IN
cord-341690-h8fqijk5	73	20	the	the	DT
cord-341690-h8fqijk5	73	21	cytoplasm	cytoplasm	NN
cord-341690-h8fqijk5	73	22	,	,	,
cord-341690-h8fqijk5	73	23	the	the	DT
cord-341690-h8fqijk5	73	24	protrusions	protrusion	NNS
cord-341690-h8fqijk5	73	25	in	in	IN
cord-341690-h8fqijk5	73	26	the	the	DT
cord-341690-h8fqijk5	73	27	cell	cell	NN
cord-341690-h8fqijk5	73	28	membrance	membrance	NN
cord-341690-h8fqijk5	73	29	reduced	reduce	VBN
cord-341690-h8fqijk5	73	30	significantly	significantly	RB
cord-341690-h8fqijk5	73	31	.	.	.
cord-341690-h8fqijk5	74	1	The	the	DT
cord-341690-h8fqijk5	74	2	transient	transient	JJ
cord-341690-h8fqijk5	74	3	increased	increase	VBD
cord-341690-h8fqijk5	74	4	in	in	IN
cord-341690-h8fqijk5	74	5	p	p	NN
cord-341690-h8fqijk5	74	6	-	-	HYPH
cord-341690-h8fqijk5	74	7	cofilin	cofilin	JJ
cord-341690-h8fqijk5	74	8	level	level	NN
cord-341690-h8fqijk5	74	9	in	in	IN
cord-341690-h8fqijk5	74	10	the	the	DT
cord-341690-h8fqijk5	74	11	cytoplasm	cytoplasm	NN
cord-341690-h8fqijk5	74	12	from	from	IN
cord-341690-h8fqijk5	74	13	1	1	CD
cord-341690-h8fqijk5	74	14	mpi	mpi	NNP
cord-341690-h8fqijk5	74	15	to	to	IN
cord-341690-h8fqijk5	74	16	30	30	CD
cord-341690-h8fqijk5	74	17	mpi	mpi	NN
cord-341690-h8fqijk5	74	18	correlated	correlate	VBN
cord-341690-h8fqijk5	74	19	with	with	IN
cord-341690-h8fqijk5	74	20	the	the	DT
cord-341690-h8fqijk5	74	21	F	F	NNP
cord-341690-h8fqijk5	74	22	-	-	HYPH
cord-341690-h8fqijk5	74	23	actin	actin	JJ
cord-341690-h8fqijk5	74	24	filaments	filament	NNS
cord-341690-h8fqijk5	74	25	around	around	IN
cord-341690-h8fqijk5	74	26	the	the	DT
cord-341690-h8fqijk5	74	27	cell	cell	NN
cord-341690-h8fqijk5	74	28	membrane	membrane	NN
cord-341690-h8fqijk5	74	29	and	and	CC
cord-341690-h8fqijk5	74	30	the	the	DT
cord-341690-h8fqijk5	74	31	formation	formation	NN
cord-341690-h8fqijk5	74	32	of	of	IN
cord-341690-h8fqijk5	74	33	multiple	multiple	JJ
cord-341690-h8fqijk5	74	34	TGEV	TGEV	NNP
cord-341690-h8fqijk5	74	35	particles	particle	NNS
cord-341690-h8fqijk5	74	36	were	be	VBD
cord-341690-h8fqijk5	74	37	labeled	label	VBN
cord-341690-h8fqijk5	74	38	with	with	IN
cord-341690-h8fqijk5	74	39	fluorescent	fluorescent	NN
cord-341690-h8fqijk5	74	40	probe	probe	NN
cord-341690-h8fqijk5	74	41	Dylight	Dylight	NNP
cord-341690-h8fqijk5	74	42	594	594	CD
cord-341690-h8fqijk5	74	43	,	,	,
cord-341690-h8fqijk5	74	44	IPEC	IPEC	NNP
cord-341690-h8fqijk5	74	45	-	-	HYPH
cord-341690-h8fqijk5	74	46	J2	j2	NN
cord-341690-h8fqijk5	74	47	cells	cell	NNS
cord-341690-h8fqijk5	74	48	were	be	VBD
cord-341690-h8fqijk5	74	49	incubated	incubate	VBN
cord-341690-h8fqijk5	74	50	with	with	IN
cord-341690-h8fqijk5	74	51	DyLight	DyLight	NNP
cord-341690-h8fqijk5	74	52	594	594	CD
cord-341690-h8fqijk5	74	53	labeled	label	VBN
cord-341690-h8fqijk5	74	54	TGEV	TGEV	NNP
cord-341690-h8fqijk5	74	55	at	at	IN
cord-341690-h8fqijk5	74	56	4	4	CD
cord-341690-h8fqijk5	74	57	°	°	NN
cord-341690-h8fqijk5	74	58	C	c	NN
cord-341690-h8fqijk5	74	59	for	for	IN
cord-341690-h8fqijk5	74	60	1	1	CD
cord-341690-h8fqijk5	74	61	h	h	NN
cord-341690-h8fqijk5	74	62	,	,	,
cord-341690-h8fqijk5	74	63	then	then	RB
cord-341690-h8fqijk5	74	64	shifted	shift	VBD
cord-341690-h8fqijk5	74	65	to	to	IN
cord-341690-h8fqijk5	74	66	37	37	CD
cord-341690-h8fqijk5	74	67	°	°	NN
cord-341690-h8fqijk5	74	68	C	c	NN
cord-341690-h8fqijk5	74	69	,	,	,
cord-341690-h8fqijk5	74	70	fixed	fix	VBN
cord-341690-h8fqijk5	74	71	at	at	IN
cord-341690-h8fqijk5	74	72	30	30	CD
cord-341690-h8fqijk5	74	73	mpi	mpi	NN
cord-341690-h8fqijk5	74	74	and	and	CC
cord-341690-h8fqijk5	74	75	60	60	CD
cord-341690-h8fqijk5	74	76	mpi	mpi	NNP
cord-341690-h8fqijk5	74	77	,	,	,
cord-341690-h8fqijk5	74	78	F	F	NNP
cord-341690-h8fqijk5	74	79	-	-	HYPH
cord-341690-h8fqijk5	74	80	actin	actin	NNP
cord-341690-h8fqijk5	74	81	stained	stain	VBN
cord-341690-h8fqijk5	74	82	with	with	IN
cord-341690-h8fqijk5	74	83	phalloidin	phalloidin	NNS
cord-341690-h8fqijk5	74	84	(	(	-LRB-
cord-341690-h8fqijk5	74	85	Green	Green	NNP
cord-341690-h8fqijk5	74	86	)	)	-RRB-
cord-341690-h8fqijk5	74	87	.	.	.
cord-341690-h8fqijk5	75	1	Images	image	NNS
cord-341690-h8fqijk5	75	2	were	be	VBD
cord-341690-h8fqijk5	75	3	captured	capture	VBN
cord-341690-h8fqijk5	75	4	with	with	IN
cord-341690-h8fqijk5	75	5	a	a	DT
cord-341690-h8fqijk5	75	6	Zeiss	Zeiss	NNP
cord-341690-h8fqijk5	75	7	LSM710	LSM710	NNP
cord-341690-h8fqijk5	75	8	confocal	confocal	JJ
cord-341690-h8fqijk5	75	9	laser	laser	NN
cord-341690-h8fqijk5	75	10	-	-	HYPH
cord-341690-h8fqijk5	75	11	scanning	scan	VBG
cord-341690-h8fqijk5	75	12	microscopy	microscopy	NN
cord-341690-h8fqijk5	75	13	system	system	NN
cord-341690-h8fqijk5	75	14	and	and	CC
cord-341690-h8fqijk5	75	15	rendered	render	VBD
cord-341690-h8fqijk5	75	16	three	three	CD
cord-341690-h8fqijk5	75	17	-	-	HYPH
cord-341690-h8fqijk5	75	18	dimensional	dimensional	JJ
cord-341690-h8fqijk5	75	19	(	(	-LRB-
cord-341690-h8fqijk5	75	20	3D	3D	NNP
cord-341690-h8fqijk5	75	21	)	)	-RRB-
cord-341690-h8fqijk5	75	22	images	image	NNS
cord-341690-h8fqijk5	75	23	.	.	.
cord-341690-h8fqijk5	76	1	Scale	scale	NN
cord-341690-h8fqijk5	76	2	bar	bar	NN
cord-341690-h8fqijk5	76	3	=	=	SYM
cord-341690-h8fqijk5	76	4	10	10	CD
cord-341690-h8fqijk5	76	5	μm	μm	NN
cord-341690-h8fqijk5	76	6	.	.	.
cord-341690-h8fqijk5	76	7	D.	D.	NNP
cord-341690-h8fqijk5	76	8	to	to	IN
cord-341690-h8fqijk5	76	9	F.	F.	NNP
cord-341690-h8fqijk5	76	10	Concentrationdependent	Concentrationdependent	NNP
cord-341690-h8fqijk5	76	11	inhibition	inhibition	NN
cord-341690-h8fqijk5	76	12	of	of	IN
cord-341690-h8fqijk5	76	13	TGEV	TGEV	NNP
cord-341690-h8fqijk5	76	14	(	(	-LRB-
cord-341690-h8fqijk5	76	15	MOI	MOI	NNP
cord-341690-h8fqijk5	76	16	=	=	SYM
cord-341690-h8fqijk5	76	17	2	2	CD
cord-341690-h8fqijk5	76	18	)	)	-RRB-
cord-341690-h8fqijk5	76	19	entry	entry	NN
cord-341690-h8fqijk5	76	20	by	by	IN
cord-341690-h8fqijk5	76	21	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	76	22	inhibitors	inhibitor	NNS
cord-341690-h8fqijk5	76	23	.	.	.
cord-341690-h8fqijk5	77	1	G.	G.	NNP
cord-341690-h8fqijk5	77	2	and	and	CC
cord-341690-h8fqijk5	77	3	H.	H.	NNP
cord-341690-h8fqijk5	77	4	Cells	cell	NNS
cord-341690-h8fqijk5	77	5	were	be	VBD
cord-341690-h8fqijk5	77	6	incubated	incubate	VBN
cord-341690-h8fqijk5	77	7	with	with	IN
cord-341690-h8fqijk5	77	8	TGEV	TGEV	NNP
cord-341690-h8fqijk5	77	9	(	(	-LRB-
cord-341690-h8fqijk5	77	10	MOI	MOI	NNP
cord-341690-h8fqijk5	77	11	=	=	SYM
cord-341690-h8fqijk5	77	12	2	2	CD
cord-341690-h8fqijk5	77	13	)	)	-RRB-
cord-341690-h8fqijk5	77	14	at	at	IN
cord-341690-h8fqijk5	77	15	4	4	CD
cord-341690-h8fqijk5	77	16	°	°	NN
cord-341690-h8fqijk5	77	17	C	c	NN
cord-341690-h8fqijk5	77	18	for	for	IN
cord-341690-h8fqijk5	77	19	1	1	CD
cord-341690-h8fqijk5	77	20	h	h	NN
cord-341690-h8fqijk5	77	21	,	,	,
cord-341690-h8fqijk5	77	22	unbound	unbound	JJ
cord-341690-h8fqijk5	77	23	virus	virus	NN
cord-341690-h8fqijk5	77	24	removed	remove	VBN
cord-341690-h8fqijk5	77	25	,	,	,
cord-341690-h8fqijk5	77	26	and	and	CC
cord-341690-h8fqijk5	77	27	cells	cell	NNS
cord-341690-h8fqijk5	77	28	were	be	VBD
cord-341690-h8fqijk5	77	29	then	then	RB
cord-341690-h8fqijk5	77	30	incubated	incubate	VBN
cord-341690-h8fqijk5	77	31	at	at	IN
cord-341690-h8fqijk5	77	32	37	37	CD
cord-341690-h8fqijk5	77	33	°	°	NN
cord-341690-h8fqijk5	77	34	C	c	NN
cord-341690-h8fqijk5	77	35	.	.	.
cord-341690-h8fqijk5	78	1	Levels	level	NNS
cord-341690-h8fqijk5	78	2	of	of	IN
cord-341690-h8fqijk5	78	3	p	p	NN
cord-341690-h8fqijk5	78	4	-	-	HYPH
cord-341690-h8fqijk5	78	5	cofilin	cofilin	NN
cord-341690-h8fqijk5	78	6	,	,	,
cord-341690-h8fqijk5	78	7	cofilin	cofilin	NN
cord-341690-h8fqijk5	78	8	and	and	CC
cord-341690-h8fqijk5	78	9	p	p	NN
cord-341690-h8fqijk5	78	10	-	-	:
cord-341690-h8fqijk5	78	11	LIMK	LIMK	NNP
cord-341690-h8fqijk5	78	12	were	be	VBD
cord-341690-h8fqijk5	78	13	measured	measure	VBN
cord-341690-h8fqijk5	78	14	by	by	IN
cord-341690-h8fqijk5	78	15	Western	western	JJ
cord-341690-h8fqijk5	78	16	blotting	blotting	NN
cord-341690-h8fqijk5	78	17	using	use	VBG
cord-341690-h8fqijk5	78	18	either	either	CC
cord-341690-h8fqijk5	78	19	mAb	mab	NN
cord-341690-h8fqijk5	78	20	specific	specific	JJ
cord-341690-h8fqijk5	78	21	for	for	IN
cord-341690-h8fqijk5	78	22	p	p	NN
cord-341690-h8fqijk5	78	23	-	-	HYPH
cord-341690-h8fqijk5	78	24	cofilin	cofilin	NN
cord-341690-h8fqijk5	78	25	,	,	,
cord-341690-h8fqijk5	78	26	or	or	CC
cord-341690-h8fqijk5	78	27	pAb	pab	VB
cord-341690-h8fqijk5	78	28	for	for	IN
cord-341690-h8fqijk5	78	29	p	p	NN
cord-341690-h8fqijk5	78	30	-	-	HYPH
cord-341690-h8fqijk5	78	31	LIMK	LIMK	NNP
cord-341690-h8fqijk5	78	32	,	,	,
cord-341690-h8fqijk5	78	33	cofilin	cofilin	NN
cord-341690-h8fqijk5	78	34	.	.	.
cord-341690-h8fqijk5	79	1	I.	I.	NNP
cord-341690-h8fqijk5	79	2	and	and	CC
cord-341690-h8fqijk5	79	3	J.	J.	NNP
cord-341690-h8fqijk5	80	1	The	the	DT
cord-341690-h8fqijk5	80	2	amount	amount	NN
cord-341690-h8fqijk5	80	3	of	of	IN
cord-341690-h8fqijk5	80	4	p	p	NN
cord-341690-h8fqijk5	80	5	-	-	:
cord-341690-h8fqijk5	80	6	cofilin	cofilin	NN
cord-341690-h8fqijk5	80	7	and	and	CC
cord-341690-h8fqijk5	80	8	cofilin	cofilin	NNP
cord-341690-h8fqijk5	80	9	were	be	VBD
cord-341690-h8fqijk5	80	10	quantified	quantify	VBN
cord-341690-h8fqijk5	80	11	.	.	.
cord-341690-h8fqijk5	81	1	Statistical	statistical	JJ
cord-341690-h8fqijk5	81	2	significance	significance	NN
cord-341690-h8fqijk5	81	3	was	be	VBD
cord-341690-h8fqijk5	81	4	assessed	assess	VBN
cord-341690-h8fqijk5	81	5	by	by	IN
cord-341690-h8fqijk5	81	6	Student	Student	NNP
cord-341690-h8fqijk5	81	7	's	's	POS
cord-341690-h8fqijk5	81	8	t	t	NN
cord-341690-h8fqijk5	81	9	-	-	HYPH
cord-341690-h8fqijk5	81	10	test	test	NN
cord-341690-h8fqijk5	81	11	.	.	.
cord-341690-h8fqijk5	82	1	Differences	difference	NNS
cord-341690-h8fqijk5	82	2	were	be	VBD
cord-341690-h8fqijk5	82	3	considered	consider	VBN
cord-341690-h8fqijk5	82	4	significant	significant	JJ
cord-341690-h8fqijk5	82	5	at	at	IN
cord-341690-h8fqijk5	82	6	(	(	-LRB-
cord-341690-h8fqijk5	82	7	*	*	NFP
cord-341690-h8fqijk5	82	8	)	)	-RRB-
cord-341690-h8fqijk5	82	9	0.01	0.01	CD
cord-341690-h8fqijk5	82	10	<	<	XX
cord-341690-h8fqijk5	82	11	p	p	XX
cord-341690-h8fqijk5	82	12	<	<	XX
cord-341690-h8fqijk5	82	13	0.05	0.05	CD
cord-341690-h8fqijk5	82	14	,	,	,
cord-341690-h8fqijk5	82	15	(	(	-LRB-
cord-341690-h8fqijk5	83	1	*	*	NFP
cord-341690-h8fqijk5	83	2	*	*	NFP
cord-341690-h8fqijk5	83	3	)	)	-RRB-
cord-341690-h8fqijk5	83	4	p	p	NN
cord-341690-h8fqijk5	83	5	<	<	XX
cord-341690-h8fqijk5	83	6	0.01	0.01	CD
cord-341690-h8fqijk5	83	7	.	.	.
cord-341690-h8fqijk5	84	1	All	all	DT
cord-341690-h8fqijk5	84	2	experiments	experiment	NNS
cord-341690-h8fqijk5	84	3	were	be	VBD
cord-341690-h8fqijk5	84	4	performed	perform	VBN
cord-341690-h8fqijk5	84	5	separately	separately	RB
cord-341690-h8fqijk5	84	6	three	three	CD
cord-341690-h8fqijk5	84	7	times	time	NNS
cord-341690-h8fqijk5	84	8	.	.	.
cord-341690-h8fqijk5	85	1	infection	infection	NN
cord-341690-h8fqijk5	85	2	.	.	.
cord-341690-h8fqijk5	86	1	Cells	cell	NNS
cord-341690-h8fqijk5	86	2	were	be	VBD
cord-341690-h8fqijk5	86	3	fixed	fix	VBN
cord-341690-h8fqijk5	86	4	at	at	IN
cord-341690-h8fqijk5	86	5	the	the	DT
cord-341690-h8fqijk5	86	6	indicated	indicate	VBN
cord-341690-h8fqijk5	86	7	time	time	NN
cord-341690-h8fqijk5	86	8	points	point	NNS
cord-341690-h8fqijk5	86	9	,	,	,
cord-341690-h8fqijk5	86	10	stained	stain	VBN
cord-341690-h8fqijk5	86	11	with	with	IN
cord-341690-h8fqijk5	86	12	anti	anti	JJ
cord-341690-h8fqijk5	86	13	-	-	JJ
cord-341690-h8fqijk5	86	14	p	p	JJ
cord-341690-h8fqijk5	86	15	-	-	HYPH
cord-341690-h8fqijk5	86	16	cofilin	cofilin	JJ
cord-341690-h8fqijk5	86	17	antibody	antibody	NN
cord-341690-h8fqijk5	86	18	,	,	,
cord-341690-h8fqijk5	86	19	and	and	CC
cord-341690-h8fqijk5	86	20	observed	observe	VBN
cord-341690-h8fqijk5	86	21	by	by	IN
cord-341690-h8fqijk5	86	22	confocal	confocal	JJ
cord-341690-h8fqijk5	86	23	microscopy	microscopy	NNS
cord-341690-h8fqijk5	86	24	.	.	.
cord-341690-h8fqijk5	87	1	Scale	scale	NN
cord-341690-h8fqijk5	87	2	bar	bar	NN
cord-341690-h8fqijk5	87	3	=	=	SYM
cord-341690-h8fqijk5	87	4	10μm	10μm	NN
cord-341690-h8fqijk5	87	5	.	.	.
cord-341690-h8fqijk5	88	1	B.	B.	NNP
cord-341690-h8fqijk5	89	1	The	the	DT
cord-341690-h8fqijk5	89	2	distribution	distribution	NN
cord-341690-h8fqijk5	89	3	of	of	IN
cord-341690-h8fqijk5	89	4	p	p	NN
cord-341690-h8fqijk5	89	5	-	-	:
cord-341690-h8fqijk5	89	6	cofilin	cofilin	NN
cord-341690-h8fqijk5	89	7	and	and	CC
cord-341690-h8fqijk5	89	8	F	F	NNP
cord-341690-h8fqijk5	89	9	-	-	HYPH
cord-341690-h8fqijk5	89	10	actin	actin	NNP
cord-341690-h8fqijk5	89	11	early	early	RB
cord-341690-h8fqijk5	89	12	in	in	IN
cord-341690-h8fqijk5	89	13	TGEV	TGEV	NNP
cord-341690-h8fqijk5	89	14	infection	infection	NN
cord-341690-h8fqijk5	89	15	.	.	.
cord-341690-h8fqijk5	90	1	At	at	IN
cord-341690-h8fqijk5	90	2	30	30	CD
cord-341690-h8fqijk5	90	3	mpi	mpi	NNS
cord-341690-h8fqijk5	90	4	,	,	,
cord-341690-h8fqijk5	90	5	cells	cell	NNS
cord-341690-h8fqijk5	90	6	were	be	VBD
cord-341690-h8fqijk5	90	7	fixed	fix	VBN
cord-341690-h8fqijk5	90	8	and	and	CC
cord-341690-h8fqijk5	90	9	stained	stain	VBN
cord-341690-h8fqijk5	90	10	with	with	IN
cord-341690-h8fqijk5	90	11	anti	anti	JJ
cord-341690-h8fqijk5	90	12	-	-	JJ
cord-341690-h8fqijk5	90	13	p	p	JJ
cord-341690-h8fqijk5	90	14	-	-	HYPH
cord-341690-h8fqijk5	90	15	cofilin	cofilin	JJ
cord-341690-h8fqijk5	90	16	antibody	antibody	NN
cord-341690-h8fqijk5	90	17	,	,	,
cord-341690-h8fqijk5	90	18	followed	follow	VBN
cord-341690-h8fqijk5	90	19	by	by	IN
cord-341690-h8fqijk5	90	20	Dylight	Dylight	NNP
cord-341690-h8fqijk5	90	21	488-conjugated	488-conjugated	CD
cord-341690-h8fqijk5	90	22	goat	goat	NN
cord-341690-h8fqijk5	90	23	anti	anti	JJ
cord-341690-h8fqijk5	90	24	-	-	JJ
cord-341690-h8fqijk5	90	25	rabbit	rabbit	JJ
cord-341690-h8fqijk5	90	26	IgG.	IgG.	NNP
cord-341690-h8fqijk5	90	27	F	F	NNP
cord-341690-h8fqijk5	90	28	-	-	HYPH
cord-341690-h8fqijk5	90	29	actin	actin	NNP
cord-341690-h8fqijk5	90	30	was	be	VBD
cord-341690-h8fqijk5	90	31	stained	stain	VBN
cord-341690-h8fqijk5	90	32	with	with	IN
cord-341690-h8fqijk5	90	33	phalloidin	phalloidin	NNS
cord-341690-h8fqijk5	90	34	-	-	HYPH
cord-341690-h8fqijk5	90	35	TRITC	TRITC	NNP
cord-341690-h8fqijk5	90	36	(	(	-LRB-
cord-341690-h8fqijk5	90	37	Red	Red	NNP
cord-341690-h8fqijk5	90	38	)	)	-RRB-
cord-341690-h8fqijk5	90	39	.	.	.
cord-341690-h8fqijk5	91	1	Scale	scale	NN
cord-341690-h8fqijk5	91	2	bar	bar	NN
cord-341690-h8fqijk5	91	3	=	=	SYM
cord-341690-h8fqijk5	91	4	10μm	10μm	NN
cord-341690-h8fqijk5	91	5	.	.	.
cord-341690-h8fqijk5	92	1	C.	C.	NNP
cord-341690-h8fqijk5	92	2	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	92	3	shRNA	shrna	NN
cord-341690-h8fqijk5	92	4	block	block	VBP
cord-341690-h8fqijk5	92	5	the	the	DT
cord-341690-h8fqijk5	92	6	destruction	destruction	NN
cord-341690-h8fqijk5	92	7	of	of	IN
cord-341690-h8fqijk5	92	8	actin	actin	NN
cord-341690-h8fqijk5	92	9	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	92	10	caused	cause	VBN
cord-341690-h8fqijk5	92	11	by	by	IN
cord-341690-h8fqijk5	92	12	TGEV	TGEV	NNP
cord-341690-h8fqijk5	92	13	infection	infection	NN
cord-341690-h8fqijk5	92	14	.	.	.
cord-341690-h8fqijk5	93	1	Cells	cell	NNS
cord-341690-h8fqijk5	93	2	were	be	VBD
cord-341690-h8fqijk5	93	3	incubated	incubate	VBN
cord-341690-h8fqijk5	93	4	with	with	IN
cord-341690-h8fqijk5	93	5	cofilin	cofilin	NNP
cord-341690-h8fqijk5	93	6	shRNA	shrna	NN
cord-341690-h8fqijk5	93	7	for	for	IN
cord-341690-h8fqijk5	93	8	48h	48h	NNS
cord-341690-h8fqijk5	93	9	,	,	,
cord-341690-h8fqijk5	93	10	cells	cell	NNS
cord-341690-h8fqijk5	93	11	were	be	VBD
cord-341690-h8fqijk5	93	12	infected	infect	VBN
cord-341690-h8fqijk5	93	13	with	with	IN
cord-341690-h8fqijk5	93	14	TGEV	TGEV	NNP
cord-341690-h8fqijk5	93	15	for	for	IN
cord-341690-h8fqijk5	93	16	1	1	CD
cord-341690-h8fqijk5	93	17	h	h	NN
cord-341690-h8fqijk5	94	1	,	,	,
cord-341690-h8fqijk5	94	2	F	F	NNP
cord-341690-h8fqijk5	94	3	-	-	HYPH
cord-341690-h8fqijk5	94	4	actin	actin	NNP
cord-341690-h8fqijk5	94	5	was	be	VBD
cord-341690-h8fqijk5	94	6	stained	stain	VBN
cord-341690-h8fqijk5	94	7	with	with	IN
cord-341690-h8fqijk5	94	8	phalloidin	phalloidin	NNS
cord-341690-h8fqijk5	94	9	-	-	HYPH
cord-341690-h8fqijk5	94	10	TRITC	TRITC	NNP
cord-341690-h8fqijk5	94	11	(	(	-LRB-
cord-341690-h8fqijk5	94	12	Green	Green	NNP
cord-341690-h8fqijk5	94	13	)	)	-RRB-
cord-341690-h8fqijk5	94	14	,	,	,
cord-341690-h8fqijk5	94	15	Scale	scale	NN
cord-341690-h8fqijk5	94	16	bar	bar	NN
cord-341690-h8fqijk5	94	17	=	=	SYM
cord-341690-h8fqijk5	94	18	10μm	10μm	NN
cord-341690-h8fqijk5	94	19	.	.	.
cord-341690-h8fqijk5	95	1	D.	D.	NNP
cord-341690-h8fqijk5	95	2	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	96	1	shRNA	shrna	LS
cord-341690-h8fqijk5	96	2	verification	verification	NN
cord-341690-h8fqijk5	96	3	.	.	.
cord-341690-h8fqijk5	97	1	Cells	cell	NNS
cord-341690-h8fqijk5	97	2	were	be	VBD
cord-341690-h8fqijk5	97	3	transfected	transfecte	VBN
cord-341690-h8fqijk5	97	4	with	with	IN
cord-341690-h8fqijk5	97	5	three	three	CD
cord-341690-h8fqijk5	97	6	cofilin	cofilin	NN
cord-341690-h8fqijk5	97	7	shRNAs	shRNAs	NNP
cord-341690-h8fqijk5	97	8	.	.	.
cord-341690-h8fqijk5	98	1	After	after	IN
cord-341690-h8fqijk5	98	2	48	48	CD
cord-341690-h8fqijk5	98	3	h	h	NN
cord-341690-h8fqijk5	98	4	incubation	incubation	NN
cord-341690-h8fqijk5	98	5	,	,	,
cord-341690-h8fqijk5	98	6	the	the	DT
cord-341690-h8fqijk5	98	7	expression	expression	NN
cord-341690-h8fqijk5	98	8	of	of	IN
cord-341690-h8fqijk5	98	9	cofilin	cofilin	NNP
cord-341690-h8fqijk5	98	10	was	be	VBD
cord-341690-h8fqijk5	98	11	verified	verify	VBN
cord-341690-h8fqijk5	98	12	by	by	IN
cord-341690-h8fqijk5	98	13	Western	western	JJ
cord-341690-h8fqijk5	98	14	blotting	blotting	NN
cord-341690-h8fqijk5	98	15	.	.	.
cord-341690-h8fqijk5	99	1	E.	E.	NNP
cord-341690-h8fqijk5	99	2	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	99	3	shRNAs	shRNAs	NNP
cord-341690-h8fqijk5	99	4	block	block	NN
cord-341690-h8fqijk5	99	5	TGEV	TGEV	NNP
cord-341690-h8fqijk5	99	6	entry	entry	NN
cord-341690-h8fqijk5	99	7	.	.	.
cord-341690-h8fqijk5	100	1	Cells	cell	NNS
cord-341690-h8fqijk5	100	2	were	be	VBD
cord-341690-h8fqijk5	100	3	transfected	transfecte	VBN
cord-341690-h8fqijk5	100	4	with	with	IN
cord-341690-h8fqijk5	100	5	lentiviral	lentiviral	JJ
cord-341690-h8fqijk5	100	6	vectors	vector	NNS
cord-341690-h8fqijk5	100	7	expressing	express	VBG
cord-341690-h8fqijk5	100	8	cofilin	cofilin	NNP
cord-341690-h8fqijk5	100	9	shRNAs	shRNAs	NNP
cord-341690-h8fqijk5	100	10	.	.	.
cord-341690-h8fqijk5	101	1	After	after	IN
cord-341690-h8fqijk5	101	2	48	48	CD
cord-341690-h8fqijk5	101	3	h	h	NN
cord-341690-h8fqijk5	101	4	incubation	incubation	NN
cord-341690-h8fqijk5	101	5	,	,	,
cord-341690-h8fqijk5	101	6	cells	cell	NNS
cord-341690-h8fqijk5	101	7	were	be	VBD
cord-341690-h8fqijk5	101	8	infected	infect	VBN
cord-341690-h8fqijk5	101	9	with	with	IN
cord-341690-h8fqijk5	101	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	101	11	for	for	IN
cord-341690-h8fqijk5	101	12	1	1	CD
cord-341690-h8fqijk5	101	13	h	h	NN
cord-341690-h8fqijk5	101	14	and	and	CC
cord-341690-h8fqijk5	101	15	entry	entry	NN
cord-341690-h8fqijk5	101	16	of	of	IN
cord-341690-h8fqijk5	101	17	TGEV	TGEV	NNP
cord-341690-h8fqijk5	101	18	was	be	VBD
cord-341690-h8fqijk5	101	19	evaluated	evaluate	VBN
cord-341690-h8fqijk5	101	20	by	by	IN
cord-341690-h8fqijk5	101	21	real	real	JJ
cord-341690-h8fqijk5	101	22	-	-	HYPH
cord-341690-h8fqijk5	101	23	time	time	NN
cord-341690-h8fqijk5	101	24	PCR	PCR	NNP
cord-341690-h8fqijk5	101	25	.	.	.
cord-341690-h8fqijk5	102	1	F.	F.	NNP
cord-341690-h8fqijk5	102	2	Verification	Verification	NNP
cord-341690-h8fqijk5	102	3	of	of	IN
cord-341690-h8fqijk5	102	4	expression	expression	NN
cord-341690-h8fqijk5	102	5	of	of	IN
cord-341690-h8fqijk5	102	6	WT	WT	NNP
cord-341690-h8fqijk5	102	7	cofilin	cofilin	NN
cord-341690-h8fqijk5	102	8	and	and	CC
cord-341690-h8fqijk5	102	9	mutant	mutant	JJ
cord-341690-h8fqijk5	102	10	cofilins	cofilin	NNS
cord-341690-h8fqijk5	102	11	S3A	s3a	NN
cord-341690-h8fqijk5	102	12	and	and	CC
cord-341690-h8fqijk5	102	13	S3E.	S3E.	NNP
cord-341690-h8fqijk5	102	14	Cells	Cells	NNPS
cord-341690-h8fqijk5	102	15	were	be	VBD
cord-341690-h8fqijk5	102	16	treated	treat	VBN
cord-341690-h8fqijk5	102	17	with	with	IN
cord-341690-h8fqijk5	102	18	lentiviral	lentiviral	NNP
cord-341690-h8fqijk5	102	19	particles	particle	NNS
cord-341690-h8fqijk5	102	20	expressing	express	VBG
cord-341690-h8fqijk5	102	21	WT	WT	NNP
cord-341690-h8fqijk5	102	22	cofilin	cofilin	NN
cord-341690-h8fqijk5	102	23	or	or	CC
cord-341690-h8fqijk5	102	24	mutant	mutant	JJ
cord-341690-h8fqijk5	102	25	cofilins	cofilin	NNS
cord-341690-h8fqijk5	102	26	S3A	s3a	NN
cord-341690-h8fqijk5	102	27	and	and	CC
cord-341690-h8fqijk5	102	28	S3E.	s3e.	NN
cord-341690-h8fqijk5	103	1	After	after	IN
cord-341690-h8fqijk5	103	2	48	48	CD
cord-341690-h8fqijk5	103	3	h	h	NN
cord-341690-h8fqijk5	103	4	incubation	incubation	NN
cord-341690-h8fqijk5	103	5	,	,	,
cord-341690-h8fqijk5	103	6	expression	expression	NN
cord-341690-h8fqijk5	103	7	of	of	IN
cord-341690-h8fqijk5	103	8	p	p	NN
cord-341690-h8fqijk5	103	9	-	-	:
cord-341690-h8fqijk5	103	10	cofilin	cofilin	NN
cord-341690-h8fqijk5	103	11	and	and	CC
cord-341690-h8fqijk5	103	12	cofilin	cofilin	NNP
cord-341690-h8fqijk5	103	13	were	be	VBD
cord-341690-h8fqijk5	103	14	verified	verify	VBN
cord-341690-h8fqijk5	103	15	by	by	IN
cord-341690-h8fqijk5	103	16	Western	western	JJ
cord-341690-h8fqijk5	103	17	blotting	blotting	NN
cord-341690-h8fqijk5	103	18	.	.	.
cord-341690-h8fqijk5	104	1	G.	G.	NNP
cord-341690-h8fqijk5	105	1	The	the	DT
cord-341690-h8fqijk5	105	2	WT	WT	NNP
cord-341690-h8fqijk5	105	3	cofilin	cofilin	NN
cord-341690-h8fqijk5	105	4	and	and	CC
cord-341690-h8fqijk5	105	5	mutant	mutant	JJ
cord-341690-h8fqijk5	105	6	cofilins	cofilin	NNS
cord-341690-h8fqijk5	105	7	S3A	S3A	NNP
cord-341690-h8fqijk5	105	8	and	and	CC
cord-341690-h8fqijk5	105	9	S3E	S3E	HYPH
cord-341690-h8fqijk5	105	10	block	block	VB
cord-341690-h8fqijk5	105	11	TGEV	TGEV	NNP
cord-341690-h8fqijk5	105	12	entry	entry	NN
cord-341690-h8fqijk5	105	13	.	.	.
cord-341690-h8fqijk5	106	1	Cells	cell	NNS
cord-341690-h8fqijk5	106	2	were	be	VBD
cord-341690-h8fqijk5	106	3	treated	treat	VBN
cord-341690-h8fqijk5	106	4	with	with	IN
cord-341690-h8fqijk5	106	5	lentiviral	lentiviral	NNP
cord-341690-h8fqijk5	106	6	particles	particle	NNS
cord-341690-h8fqijk5	106	7	expressing	express	VBG
cord-341690-h8fqijk5	106	8	WT	WT	NNP
cord-341690-h8fqijk5	106	9	cofilin	cofilin	NN
cord-341690-h8fqijk5	106	10	or	or	CC
cord-341690-h8fqijk5	106	11	mutant	mutant	JJ
cord-341690-h8fqijk5	106	12	cofilins	cofilin	NNS
cord-341690-h8fqijk5	106	13	S3A	s3a	NN
cord-341690-h8fqijk5	106	14	and	and	CC
cord-341690-h8fqijk5	106	15	S3E.	s3e.	NN
cord-341690-h8fqijk5	107	1	After	after	IN
cord-341690-h8fqijk5	107	2	48	48	CD
cord-341690-h8fqijk5	107	3	h	h	NN
cord-341690-h8fqijk5	107	4	incubation	incubation	NN
cord-341690-h8fqijk5	107	5	,	,	,
cord-341690-h8fqijk5	107	6	cells	cell	NNS
cord-341690-h8fqijk5	107	7	were	be	VBD
cord-341690-h8fqijk5	107	8	infected	infect	VBN
cord-341690-h8fqijk5	107	9	with	with	IN
cord-341690-h8fqijk5	107	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	107	11	for	for	IN
cord-341690-h8fqijk5	107	12	1	1	CD
cord-341690-h8fqijk5	107	13	h	h	NN
cord-341690-h8fqijk5	107	14	and	and	CC
cord-341690-h8fqijk5	107	15	entry	entry	NN
cord-341690-h8fqijk5	107	16	of	of	IN
cord-341690-h8fqijk5	107	17	TGEV	TGEV	NNP
cord-341690-h8fqijk5	107	18	was	be	VBD
cord-341690-h8fqijk5	107	19	evaluated	evaluate	VBN
cord-341690-h8fqijk5	107	20	by	by	IN
cord-341690-h8fqijk5	107	21	real	real	JJ
cord-341690-h8fqijk5	107	22	-	-	HYPH
cord-341690-h8fqijk5	107	23	time	time	NN
cord-341690-h8fqijk5	107	24	PCR	PCR	NNP
cord-341690-h8fqijk5	107	25	.	.	.
cord-341690-h8fqijk5	108	1	H.	H.	NNP
cord-341690-h8fqijk5	109	1	ARP2/3	ARP2/3	NNP
cord-341690-h8fqijk5	110	1	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	111	1	CK548	CK548	NNP
cord-341690-h8fqijk5	111	2	promotes	promote	VBZ
cord-341690-h8fqijk5	111	3	TGEV	TGEV	NNP
cord-341690-h8fqijk5	111	4	entry	entry	NN
cord-341690-h8fqijk5	111	5	.	.	.
cord-341690-h8fqijk5	112	1	IPEC	IPEC	NNP
cord-341690-h8fqijk5	112	2	-	-	HYPH
cord-341690-h8fqijk5	112	3	J2	j2	NN
cord-341690-h8fqijk5	112	4	cells	cell	NNS
cord-341690-h8fqijk5	112	5	were	be	VBD
cord-341690-h8fqijk5	112	6	pretreated	pretreate	VBN
cord-341690-h8fqijk5	112	7	with	with	IN
cord-341690-h8fqijk5	112	8	CK548	CK548	NNP
cord-341690-h8fqijk5	112	9	at	at	IN
cord-341690-h8fqijk5	112	10	different	different	JJ
cord-341690-h8fqijk5	112	11	concentrations	concentration	NNS
cord-341690-h8fqijk5	112	12	at	at	IN
cord-341690-h8fqijk5	112	13	37	37	CD
cord-341690-h8fqijk5	112	14	°	°	NN
cord-341690-h8fqijk5	112	15	C	c	NN
cord-341690-h8fqijk5	112	16	for	for	IN
cord-341690-h8fqijk5	112	17	1	1	CD
cord-341690-h8fqijk5	112	18	h	h	NN
cord-341690-h8fqijk5	112	19	,	,	,
cord-341690-h8fqijk5	112	20	for	for	IN
cord-341690-h8fqijk5	112	21	details	detail	NNS
cord-341690-h8fqijk5	112	22	concerning	concern	VBG
cord-341690-h8fqijk5	112	23	binding	binding	NN
cord-341690-h8fqijk5	112	24	and	and	CC
cord-341690-h8fqijk5	112	25	entry	entry	NN
cord-341690-h8fqijk5	112	26	assays	assay	NNS
cord-341690-h8fqijk5	112	27	,	,	,
cord-341690-h8fqijk5	112	28	see	see	VB
cord-341690-h8fqijk5	112	29	materials	material	NNS
cord-341690-h8fqijk5	112	30	and	and	CC
cord-341690-h8fqijk5	112	31	methods	method	NNS
cord-341690-h8fqijk5	112	32	.	.	.
cord-341690-h8fqijk5	113	1	Statistical	statistical	JJ
cord-341690-h8fqijk5	113	2	significance	significance	NN
cord-341690-h8fqijk5	113	3	was	be	VBD
cord-341690-h8fqijk5	113	4	assessed	assess	VBN
cord-341690-h8fqijk5	113	5	by	by	IN
cord-341690-h8fqijk5	113	6	Student	Student	NNP
cord-341690-h8fqijk5	113	7	's	's	POS
cord-341690-h8fqijk5	113	8	t	t	NN
cord-341690-h8fqijk5	113	9	-	-	HYPH
cord-341690-h8fqijk5	113	10	test	test	NN
cord-341690-h8fqijk5	113	11	.	.	.
cord-341690-h8fqijk5	114	1	Differences	difference	NNS
cord-341690-h8fqijk5	114	2	were	be	VBD
cord-341690-h8fqijk5	114	3	considered	consider	VBN
cord-341690-h8fqijk5	114	4	significant	significant	JJ
cord-341690-h8fqijk5	114	5	at	at	IN
cord-341690-h8fqijk5	114	6	(	(	-LRB-
cord-341690-h8fqijk5	114	7	*	*	NFP
cord-341690-h8fqijk5	114	8	)	)	-RRB-
cord-341690-h8fqijk5	114	9	0.01	0.01	CD
cord-341690-h8fqijk5	114	10	<	<	XX
cord-341690-h8fqijk5	114	11	p	p	XX
cord-341690-h8fqijk5	114	12	<	<	XX
cord-341690-h8fqijk5	114	13	0.05	0.05	CD
cord-341690-h8fqijk5	114	14	,	,	,
cord-341690-h8fqijk5	114	15	(	(	-LRB-
cord-341690-h8fqijk5	115	1	*	*	NFP
cord-341690-h8fqijk5	115	2	*	*	NFP
cord-341690-h8fqijk5	115	3	)	)	-RRB-
cord-341690-h8fqijk5	115	4	p	p	NN
cord-341690-h8fqijk5	115	5	<	<	XX
cord-341690-h8fqijk5	115	6	0.01	0.01	CD
cord-341690-h8fqijk5	115	7	.	.	.
cord-341690-h8fqijk5	116	1	Scale	scale	NN
cord-341690-h8fqijk5	116	2	bar	bar	NN
cord-341690-h8fqijk5	116	3	=	=	SYM
cord-341690-h8fqijk5	116	4	20	20	CD
cord-341690-h8fqijk5	116	5	μm	μm	NN
cord-341690-h8fqijk5	116	6	.	.	.
cord-341690-h8fqijk5	117	1	TGEV	TGEV	NNP
cord-341690-h8fqijk5	117	2	at	at	IN
cord-341690-h8fqijk5	117	3	a	a	DT
cord-341690-h8fqijk5	117	4	multiplicity	multiplicity	NN
cord-341690-h8fqijk5	117	5	of	of	IN
cord-341690-h8fqijk5	117	6	infection	infection	NN
cord-341690-h8fqijk5	117	7	of	of	IN
cord-341690-h8fqijk5	117	8	2	2	CD
cord-341690-h8fqijk5	117	9	(	(	-LRB-
cord-341690-h8fqijk5	117	10	MOI	MOI	NNP
cord-341690-h8fqijk5	117	11	=	=	SYM
cord-341690-h8fqijk5	117	12	2	2	CD
cord-341690-h8fqijk5	117	13	)	)	-RRB-
cord-341690-h8fqijk5	117	14	.	.	.
cord-341690-h8fqijk5	118	1	protrusions	protrusion	NNS
cord-341690-h8fqijk5	118	2	.	.	.
cord-341690-h8fqijk5	119	1	All	all	DT
cord-341690-h8fqijk5	119	2	of	of	IN
cord-341690-h8fqijk5	119	3	these	these	DT
cord-341690-h8fqijk5	119	4	results	result	NNS
cord-341690-h8fqijk5	119	5	demonstrate	demonstrate	VBP
cord-341690-h8fqijk5	119	6	that	that	IN
cord-341690-h8fqijk5	119	7	cofilin	cofilin	NN
cord-341690-h8fqijk5	119	8	involve	involve	VB
cord-341690-h8fqijk5	119	9	in	in	IN
cord-341690-h8fqijk5	119	10	the	the	DT
cord-341690-h8fqijk5	119	11	regulation	regulation	NN
cord-341690-h8fqijk5	119	12	of	of	IN
cord-341690-h8fqijk5	119	13	F	F	NNP
cord-341690-h8fqijk5	119	14	-	-	HYPH
cord-341690-h8fqijk5	119	15	actin	actin	NNP
cord-341690-h8fqijk5	119	16	early	early	RB
cord-341690-h8fqijk5	119	17	in	in	IN
cord-341690-h8fqijk5	119	18	TGEV	TGEV	NNP
cord-341690-h8fqijk5	119	19	infection	infection	NN
cord-341690-h8fqijk5	119	20	.	.	.
cord-341690-h8fqijk5	120	1	To	to	TO
cord-341690-h8fqijk5	120	2	confirm	confirm	VB
cord-341690-h8fqijk5	120	3	the	the	DT
cord-341690-h8fqijk5	120	4	role	role	NN
cord-341690-h8fqijk5	120	5	of	of	IN
cord-341690-h8fqijk5	120	6	cofilin	cofilin	NN
cord-341690-h8fqijk5	120	7	in	in	IN
cord-341690-h8fqijk5	120	8	TGEV	TGEV	NNP
cord-341690-h8fqijk5	120	9	infection	infection	NN
cord-341690-h8fqijk5	120	10	,	,	,
cord-341690-h8fqijk5	120	11	we	-PRON-	PRP
cord-341690-h8fqijk5	120	12	used	use	VBD
cord-341690-h8fqijk5	120	13	molecular	molecular	JJ
cord-341690-h8fqijk5	120	14	methods	method	NNS
cord-341690-h8fqijk5	120	15	to	to	TO
cord-341690-h8fqijk5	120	16	modify	modify	VB
cord-341690-h8fqijk5	120	17	the	the	DT
cord-341690-h8fqijk5	120	18	levels	level	NNS
cord-341690-h8fqijk5	120	19	of	of	IN
cord-341690-h8fqijk5	120	20	cofilin	cofilin	NN
cord-341690-h8fqijk5	120	21	and	and	CC
cord-341690-h8fqijk5	120	22	p	p	NN
cord-341690-h8fqijk5	120	23	-	-	HYPH
cord-341690-h8fqijk5	120	24	cofilin	cofilin	NN
cord-341690-h8fqijk5	120	25	prior	prior	RB
cord-341690-h8fqijk5	120	26	to	to	IN
cord-341690-h8fqijk5	120	27	infection	infection	NN
cord-341690-h8fqijk5	120	28	by	by	IN
cord-341690-h8fqijk5	120	29	TGEV	TGEV	NNS
cord-341690-h8fqijk5	120	30	.	.	.
cord-341690-h8fqijk5	121	1	Cells	cell	NNS
cord-341690-h8fqijk5	121	2	were	be	VBD
cord-341690-h8fqijk5	121	3	transfected	transfecte	VBN
cord-341690-h8fqijk5	121	4	with	with	IN
cord-341690-h8fqijk5	121	5	cofilin	cofilin	NN
cord-341690-h8fqijk5	121	6	targeting	target	VBG
cord-341690-h8fqijk5	121	7	shRNAs	shRNAs	NNP
cord-341690-h8fqijk5	121	8	,	,	,
cord-341690-h8fqijk5	121	9	the	the	DT
cord-341690-h8fqijk5	121	10	cofilin	cofilin	JJ
cord-341690-h8fqijk5	121	11	expression	expression	NN
cord-341690-h8fqijk5	121	12	level	level	NN
cord-341690-h8fqijk5	121	13	was	be	VBD
cord-341690-h8fqijk5	121	14	decreased	decrease	VBN
cord-341690-h8fqijk5	121	15	significantly	significantly	RB
cord-341690-h8fqijk5	122	1	(	(	-LRB-
cord-341690-h8fqijk5	122	2	Figure	figure	NN
cord-341690-h8fqijk5	122	3	 	 	_SP
cord-341690-h8fqijk5	122	4	2C	2C	NNP
cord-341690-h8fqijk5	122	5	)	)	-RRB-
cord-341690-h8fqijk5	122	6	,	,	,
cord-341690-h8fqijk5	122	7	and	and	CC
cord-341690-h8fqijk5	122	8	TGEV	TGEV	NNP
cord-341690-h8fqijk5	122	9	entry	entry	NN
cord-341690-h8fqijk5	122	10	level	level	NN
cord-341690-h8fqijk5	122	11	was	be	VBD
cord-341690-h8fqijk5	122	12	decreased	decrease	VBN
cord-341690-h8fqijk5	122	13	(	(	-LRB-
cord-341690-h8fqijk5	122	14	Figure	figure	NN
cord-341690-h8fqijk5	122	15	2D	2d	NN
cord-341690-h8fqijk5	122	16	)	)	-RRB-
cord-341690-h8fqijk5	122	17	.	.	.
cord-341690-h8fqijk5	123	1	Cells	cell	NNS
cord-341690-h8fqijk5	123	2	were	be	VBD
cord-341690-h8fqijk5	123	3	also	also	RB
cord-341690-h8fqijk5	123	4	transfected	transfecte	VBN
cord-341690-h8fqijk5	123	5	with	with	IN
cord-341690-h8fqijk5	123	6	vectors	vector	NNS
cord-341690-h8fqijk5	123	7	expressing	express	VBG
cord-341690-h8fqijk5	123	8	WT	WT	NNP
cord-341690-h8fqijk5	123	9	cofilin	cofilin	NN
cord-341690-h8fqijk5	123	10	,	,	,
cord-341690-h8fqijk5	123	11	constitutively	constitutively	RB
cord-341690-h8fqijk5	123	12	non	non	JJ
cord-341690-h8fqijk5	123	13	-	-	JJ
cord-341690-h8fqijk5	123	14	phosphorylated	phosphorylated	JJ
cord-341690-h8fqijk5	123	15	mutant	mutant	JJ
cord-341690-h8fqijk5	123	16	cofilin	cofilin	NN
cord-341690-h8fqijk5	123	17	(	(	-LRB-
cord-341690-h8fqijk5	123	18	activated	activate	VBN
cord-341690-h8fqijk5	123	19	,	,	,
cord-341690-h8fqijk5	123	20	S3A	s3a	CD
cord-341690-h8fqijk5	123	21	)	)	-RRB-
cord-341690-h8fqijk5	123	22	,	,	,
cord-341690-h8fqijk5	123	23	or	or	CC
cord-341690-h8fqijk5	123	24	constitutively	constitutively	RB
cord-341690-h8fqijk5	123	25	-	-	HYPH
cord-341690-h8fqijk5	123	26	phosphorylated	phosphorylate	VBN
cord-341690-h8fqijk5	123	27	mutant	mutant	JJ
cord-341690-h8fqijk5	123	28	cofilin	cofilin	NN
cord-341690-h8fqijk5	123	29	(	(	-LRB-
cord-341690-h8fqijk5	123	30	inactivated	inactivate	VBN
cord-341690-h8fqijk5	123	31	,	,	,
cord-341690-h8fqijk5	123	32	S3E	s3e	LS
cord-341690-h8fqijk5	123	33	)	)	-RRB-
cord-341690-h8fqijk5	123	34	[	[	-LRB-
cord-341690-h8fqijk5	123	35	21	21	CD
cord-341690-h8fqijk5	123	36	,	,	,
cord-341690-h8fqijk5	123	37	22	22	CD
cord-341690-h8fqijk5	123	38	]	]	-RRB-
cord-341690-h8fqijk5	123	39	.	.	.
cord-341690-h8fqijk5	124	1	The	the	DT
cord-341690-h8fqijk5	124	2	expression	expression	NN
cord-341690-h8fqijk5	124	3	of	of	IN
cord-341690-h8fqijk5	124	4	WT	WT	NNP
cord-341690-h8fqijk5	124	5	or	or	CC
cord-341690-h8fqijk5	124	6	constitutively	constitutively	RB
cord-341690-h8fqijk5	124	7	inactivated	inactivate	VBN
cord-341690-h8fqijk5	124	8	cofilin	cofilin	NNP
cord-341690-h8fqijk5	124	9	S3E	s3e	CD
cord-341690-h8fqijk5	124	10	significantly	significantly	RB
cord-341690-h8fqijk5	124	11	increased	increase	VBD
cord-341690-h8fqijk5	124	12	the	the	DT
cord-341690-h8fqijk5	124	13	expression	expression	NN
cord-341690-h8fqijk5	124	14	of	of	IN
cord-341690-h8fqijk5	124	15	p	p	NN
cord-341690-h8fqijk5	124	16	-	-	:
cord-341690-h8fqijk5	124	17	cofilin	cofilin	NN
cord-341690-h8fqijk5	124	18	(	(	-LRB-
cord-341690-h8fqijk5	124	19	Figure	figure	NN
cord-341690-h8fqijk5	124	20	2E	2e	NN
cord-341690-h8fqijk5	124	21	)	)	-RRB-
cord-341690-h8fqijk5	124	22	.	.	.
cord-341690-h8fqijk5	125	1	All	all	DT
cord-341690-h8fqijk5	125	2	three	three	CD
cord-341690-h8fqijk5	125	3	constructs	construct	NNS
cord-341690-h8fqijk5	125	4	inhibited	inhibit	VBN
cord-341690-h8fqijk5	125	5	TGEV	TGEV	NNP
cord-341690-h8fqijk5	125	6	entry	entry	NN
cord-341690-h8fqijk5	125	7	(	(	-LRB-
cord-341690-h8fqijk5	125	8	Figure	figure	NN
cord-341690-h8fqijk5	125	9	2F	2f	NN
cord-341690-h8fqijk5	125	10	)	)	-RRB-
cord-341690-h8fqijk5	125	11	.	.	.
cord-341690-h8fqijk5	126	1	Examination	examination	NN
cord-341690-h8fqijk5	126	2	using	use	VBG
cord-341690-h8fqijk5	126	3	confocal	confocal	JJ
cord-341690-h8fqijk5	126	4	fluorescence	fluorescence	NN
cord-341690-h8fqijk5	126	5	microscopy	microscopy	NNS
cord-341690-h8fqijk5	126	6	showed	show	VBD
cord-341690-h8fqijk5	126	7	that	that	IN
cord-341690-h8fqijk5	126	8	in	in	IN
cord-341690-h8fqijk5	126	9	uninfected	uninfected	JJ
cord-341690-h8fqijk5	126	10	cells	cell	NNS
cord-341690-h8fqijk5	126	11	,	,	,
cord-341690-h8fqijk5	126	12	the	the	DT
cord-341690-h8fqijk5	126	13	F	F	NNP
cord-341690-h8fqijk5	126	14	-	-	HYPH
cord-341690-h8fqijk5	126	15	actin	actin	NNP
cord-341690-h8fqijk5	126	16	partially	partially	RB
cord-341690-h8fqijk5	126	17	depolymerized	depolymerize	VBD
cord-341690-h8fqijk5	126	18	in	in	IN
cord-341690-h8fqijk5	126	19	WT	WT	NNP
cord-341690-h8fqijk5	126	20	cofilin	cofilin	NN
cord-341690-h8fqijk5	126	21	-	-	HYPH
cord-341690-h8fqijk5	126	22	expressing	express	VBG
cord-341690-h8fqijk5	126	23	cells	cell	NNS
cord-341690-h8fqijk5	126	24	and	and	CC
cord-341690-h8fqijk5	126	25	in	in	IN
cord-341690-h8fqijk5	126	26	constitutively	constitutively	RB
cord-341690-h8fqijk5	126	27	activated	activate	VBN
cord-341690-h8fqijk5	126	28	cofilinS3A	cofilinS3A	NNP
cord-341690-h8fqijk5	126	29	-	-	HYPH
cord-341690-h8fqijk5	126	30	expressing	express	VBG
cord-341690-h8fqijk5	126	31	cells	cell	NNS
cord-341690-h8fqijk5	126	32	,	,	,
cord-341690-h8fqijk5	126	33	while	while	IN
cord-341690-h8fqijk5	126	34	the	the	DT
cord-341690-h8fqijk5	126	35	F	F	NNP
cord-341690-h8fqijk5	126	36	-	-	HYPH
cord-341690-h8fqijk5	126	37	actin	actin	NNP
cord-341690-h8fqijk5	126	38	in	in	IN
cord-341690-h8fqijk5	126	39	constitutively	constitutively	RB
cord-341690-h8fqijk5	126	40	inactivated	inactivate	VBN
cord-341690-h8fqijk5	126	41	cofilinS3E	cofilinS3E	NNP
cord-341690-h8fqijk5	126	42	-	-	HYPH
cord-341690-h8fqijk5	126	43	expressing	express	VBG
cord-341690-h8fqijk5	126	44	cells	cell	NNS
cord-341690-h8fqijk5	126	45	,	,	,
cord-341690-h8fqijk5	126	46	polymerized	polymerize	VBN
cord-341690-h8fqijk5	126	47	around	around	IN
cord-341690-h8fqijk5	126	48	the	the	DT
cord-341690-h8fqijk5	126	49	cell	cell	NN
cord-341690-h8fqijk5	126	50	membrane	membrane	NN
cord-341690-h8fqijk5	126	51	(	(	-LRB-
cord-341690-h8fqijk5	126	52	Figure	figure	NN
cord-341690-h8fqijk5	126	53	S2	s2	NN
cord-341690-h8fqijk5	126	54	)	)	-RRB-
cord-341690-h8fqijk5	126	55	.	.	.
cord-341690-h8fqijk5	127	1	We	-PRON-	PRP
cord-341690-h8fqijk5	127	2	also	also	RB
cord-341690-h8fqijk5	127	3	explored	explore	VBD
cord-341690-h8fqijk5	127	4	the	the	DT
cord-341690-h8fqijk5	127	5	role	role	NN
cord-341690-h8fqijk5	127	6	of	of	IN
cord-341690-h8fqijk5	127	7	actin	actin	NN
cord-341690-h8fqijk5	127	8	-	-	HYPH
cord-341690-h8fqijk5	127	9	related	relate	VBN
cord-341690-h8fqijk5	127	10	protein	protein	NN
cord-341690-h8fqijk5	127	11	2/3	2/3	CD
cord-341690-h8fqijk5	128	1	(	(	-LRB-
cord-341690-h8fqijk5	128	2	ARP2/3	ARP2/3	NNP
cord-341690-h8fqijk5	128	3	)	)	-RRB-
cord-341690-h8fqijk5	129	1	in	in	IN
cord-341690-h8fqijk5	129	2	TGEV	TGEV	NNP
cord-341690-h8fqijk5	129	3	entry	entry	NN
cord-341690-h8fqijk5	129	4	using	use	VBG
cord-341690-h8fqijk5	129	5	its	-PRON-	PRP$
cord-341690-h8fqijk5	129	6	specific	specific	JJ
cord-341690-h8fqijk5	129	7	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	129	8	CK548	ck548	NN
cord-341690-h8fqijk5	129	9	.	.	.
cord-341690-h8fqijk5	130	1	Cells	cell	NNS
cord-341690-h8fqijk5	130	2	were	be	VBD
cord-341690-h8fqijk5	130	3	treated	treat	VBN
cord-341690-h8fqijk5	130	4	with	with	IN
cord-341690-h8fqijk5	130	5	different	different	JJ
cord-341690-h8fqijk5	130	6	concentrations	concentration	NNS
cord-341690-h8fqijk5	130	7	of	of	IN
cord-341690-h8fqijk5	130	8	CK548	ck548	NN
cord-341690-h8fqijk5	130	9	at	at	IN
cord-341690-h8fqijk5	130	10	37	37	CD
cord-341690-h8fqijk5	130	11	°	°	NN
cord-341690-h8fqijk5	130	12	C	c	NN
cord-341690-h8fqijk5	130	13	for	for	IN
cord-341690-h8fqijk5	130	14	1h	1h	CD
cord-341690-h8fqijk5	130	15	prior	prior	RB
cord-341690-h8fqijk5	130	16	to	to	IN
cord-341690-h8fqijk5	130	17	TGEV	TGEV	NNP
cord-341690-h8fqijk5	130	18	infection	infection	NN
cord-341690-h8fqijk5	130	19	.	.	.
cord-341690-h8fqijk5	131	1	CK548	CK548	NNP
cord-341690-h8fqijk5	131	2	did	do	VBD
cord-341690-h8fqijk5	131	3	not	not	RB
cord-341690-h8fqijk5	131	4	inhibit	inhibit	VB
cord-341690-h8fqijk5	131	5	virus	virus	NN
cord-341690-h8fqijk5	131	6	binding	bind	VBG
cord-341690-h8fqijk5	131	7	,	,	,
cord-341690-h8fqijk5	131	8	but	but	CC
cord-341690-h8fqijk5	131	9	promoted	promote	VBD
cord-341690-h8fqijk5	131	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	131	11	entry	entry	NN
cord-341690-h8fqijk5	131	12	(	(	-LRB-
cord-341690-h8fqijk5	131	13	Figure	figure	NN
cord-341690-h8fqijk5	131	14	2	2	CD
cord-341690-h8fqijk5	131	15	G	g	NN
cord-341690-h8fqijk5	131	16	)	)	-RRB-
cord-341690-h8fqijk5	131	17	.	.	.
cord-341690-h8fqijk5	132	1	We	-PRON-	PRP
cord-341690-h8fqijk5	132	2	pretreated	pretreate	VBD
cord-341690-h8fqijk5	132	3	cells	cell	NNS
cord-341690-h8fqijk5	132	4	with	with	IN
cord-341690-h8fqijk5	132	5	several	several	JJ
cord-341690-h8fqijk5	132	6	RHO	rho	NN
cord-341690-h8fqijk5	132	7	-	-	HYPH
cord-341690-h8fqijk5	132	8	family	family	NN
cord-341690-h8fqijk5	132	9	-	-	HYPH
cord-341690-h8fqijk5	132	10	GTPases	gtpase	NNS
cord-341690-h8fqijk5	132	11	inhibitors	inhibitor	NNS
cord-341690-h8fqijk5	132	12	prior	prior	RB
cord-341690-h8fqijk5	132	13	to	to	IN
cord-341690-h8fqijk5	132	14	TGEV	TGEV	NNP
cord-341690-h8fqijk5	132	15	infection	infection	NN
cord-341690-h8fqijk5	132	16	to	to	TO
cord-341690-h8fqijk5	132	17	determine	determine	VB
cord-341690-h8fqijk5	132	18	whether	whether	IN
cord-341690-h8fqijk5	132	19	some	some	DT
cord-341690-h8fqijk5	132	20	were	be	VBD
cord-341690-h8fqijk5	132	21	the	the	DT
cord-341690-h8fqijk5	132	22	upstream	upstream	JJ
cord-341690-h8fqijk5	132	23	regulators	regulator	NNS
cord-341690-h8fqijk5	132	24	of	of	IN
cord-341690-h8fqijk5	132	25	cofilin	cofilin	NNP
cord-341690-h8fqijk5	132	26	.	.	.
cord-341690-h8fqijk5	133	1	ROCK	rock	NN
cord-341690-h8fqijk5	133	2	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	134	1	Y27632	Y27632	NNP
cord-341690-h8fqijk5	134	2	did	do	VBD
cord-341690-h8fqijk5	134	3	not	not	RB
cord-341690-h8fqijk5	134	4	inhibit	inhibit	VB
cord-341690-h8fqijk5	134	5	TGEV	TGEV	NNP
cord-341690-h8fqijk5	134	6	binding	bind	VBG
cord-341690-h8fqijk5	134	7	as	as	RB
cord-341690-h8fqijk5	134	8	well	well	RB
cord-341690-h8fqijk5	134	9	as	as	IN
cord-341690-h8fqijk5	134	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	134	11	entry	entry	NN
cord-341690-h8fqijk5	134	12	(	(	-LRB-
cord-341690-h8fqijk5	134	13	Figure	figure	NN
cord-341690-h8fqijk5	134	14	3A	3a	CD
cord-341690-h8fqijk5	134	15	)	)	-RRB-
cord-341690-h8fqijk5	134	16	.	.	.
cord-341690-h8fqijk5	135	1	PAKs	PAKs	NNP
cord-341690-h8fqijk5	135	2	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	135	3	IPA-3	IPA-3	NNP
cord-341690-h8fqijk5	135	4	also	also	RB
cord-341690-h8fqijk5	135	5	had	have	VBD
cord-341690-h8fqijk5	135	6	no	no	DT
cord-341690-h8fqijk5	135	7	effect	effect	NN
cord-341690-h8fqijk5	135	8	on	on	IN
cord-341690-h8fqijk5	135	9	TGEV	TGEV	NNP
cord-341690-h8fqijk5	135	10	binding	bind	VBG
cord-341690-h8fqijk5	135	11	,	,	,
cord-341690-h8fqijk5	135	12	but	but	CC
cord-341690-h8fqijk5	135	13	decreased	decrease	VBD
cord-341690-h8fqijk5	135	14	TGEV	TGEV	NNP
cord-341690-h8fqijk5	135	15	entry	entry	NN
cord-341690-h8fqijk5	135	16	in	in	IN
cord-341690-h8fqijk5	135	17	a	a	DT
cord-341690-h8fqijk5	135	18	dose	dose	NN
cord-341690-h8fqijk5	135	19	dependent	dependent	JJ
cord-341690-h8fqijk5	135	20	manner	manner	NN
cord-341690-h8fqijk5	135	21	(	(	-LRB-
cord-341690-h8fqijk5	135	22	Figure	figure	NN
cord-341690-h8fqijk5	135	23	3B	3b	CD
cord-341690-h8fqijk5	135	24	)	)	-RRB-
cord-341690-h8fqijk5	135	25	.	.	.
cord-341690-h8fqijk5	136	1	IPA-3	ipa-3	JJ
cord-341690-h8fqijk5	136	2	inhibited	inhibited	JJ
cord-341690-h8fqijk5	136	3	LIMK	LIMK	NNP
cord-341690-h8fqijk5	136	4	activation	activation	NN
cord-341690-h8fqijk5	136	5	and	and	CC
cord-341690-h8fqijk5	136	6	cofilin	cofilin	NN
cord-341690-h8fqijk5	136	7	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	136	8	,	,	,
cord-341690-h8fqijk5	136	9	while	while	IN
cord-341690-h8fqijk5	136	10	ROCK	ROCK	NNP
cord-341690-h8fqijk5	136	11	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	136	12	Y27632	Y27632	NNP
cord-341690-h8fqijk5	136	13	had	have	VBD
cord-341690-h8fqijk5	136	14	no	no	DT
cord-341690-h8fqijk5	136	15	inhibitory	inhibitory	JJ
cord-341690-h8fqijk5	136	16	effect	effect	NN
cord-341690-h8fqijk5	136	17	(	(	-LRB-
cord-341690-h8fqijk5	136	18	Figure	figure	NN
cord-341690-h8fqijk5	136	19	3C	3c	NN
cord-341690-h8fqijk5	136	20	)	)	-RRB-
cord-341690-h8fqijk5	136	21	.	.	.
cord-341690-h8fqijk5	137	1	Using	use	VBG
cord-341690-h8fqijk5	137	2	confocal	confocal	JJ
cord-341690-h8fqijk5	137	3	fluorescence	fluorescence	NN
cord-341690-h8fqijk5	137	4	microscopy	microscopy	NNS
cord-341690-h8fqijk5	137	5	,	,	,
cord-341690-h8fqijk5	137	6	we	-PRON-	PRP
cord-341690-h8fqijk5	137	7	also	also	RB
cord-341690-h8fqijk5	137	8	observed	observe	VBD
cord-341690-h8fqijk5	137	9	that	that	IN
cord-341690-h8fqijk5	137	10	IPA-3	IPA-3	NNP
cord-341690-h8fqijk5	137	11	appeared	appear	VBD
cord-341690-h8fqijk5	137	12	to	to	TO
cord-341690-h8fqijk5	137	13	inhibit	inhibit	VB
cord-341690-h8fqijk5	137	14	the	the	DT
cord-341690-h8fqijk5	137	15	destruction	destruction	NN
cord-341690-h8fqijk5	137	16	of	of	IN
cord-341690-h8fqijk5	137	17	F	f	NN
cord-341690-h8fqijk5	137	18	-	-	HYPH
cord-341690-h8fqijk5	137	19	actin	actin	NN
cord-341690-h8fqijk5	137	20	by	by	IN
cord-341690-h8fqijk5	137	21	TGEV	TGEV	NNP
cord-341690-h8fqijk5	137	22	infection	infection	NN
cord-341690-h8fqijk5	137	23	,	,	,
cord-341690-h8fqijk5	137	24	but	but	CC
cord-341690-h8fqijk5	137	25	LY294002	ly294002	PRP
cord-341690-h8fqijk5	137	26	could	could	MD
cord-341690-h8fqijk5	137	27	n't	not	RB
cord-341690-h8fqijk5	137	28	inhibit	inhibit	VB
cord-341690-h8fqijk5	137	29	the	the	DT
cord-341690-h8fqijk5	137	30	destruction	destruction	NN
cord-341690-h8fqijk5	137	31	of	of	IN
cord-341690-h8fqijk5	137	32	F	f	NN
cord-341690-h8fqijk5	137	33	-	-	HYPH
cord-341690-h8fqijk5	137	34	actin	actin	NN
cord-341690-h8fqijk5	137	35	by	by	IN
cord-341690-h8fqijk5	137	36	TGEV	TGEV	NNP
cord-341690-h8fqijk5	137	37	infection	infection	NN
cord-341690-h8fqijk5	137	38	(	(	-LRB-
cord-341690-h8fqijk5	137	39	Figure	figure	NN
cord-341690-h8fqijk5	137	40	3J	3j	CD
cord-341690-h8fqijk5	137	41	)	)	-RRB-
cord-341690-h8fqijk5	137	42	.	.	.
cord-341690-h8fqijk5	138	1	The	the	DT
cord-341690-h8fqijk5	138	2	effect	effect	NN
cord-341690-h8fqijk5	138	3	of	of	IN
cord-341690-h8fqijk5	138	4	these	these	DT
cord-341690-h8fqijk5	138	5	inhibitors	inhibitor	NNS
cord-341690-h8fqijk5	138	6	on	on	IN
cord-341690-h8fqijk5	138	7	cell	cell	NN
cord-341690-h8fqijk5	138	8	viability	viability	NN
cord-341690-h8fqijk5	138	9	was	be	VBD
cord-341690-h8fqijk5	138	10	shown	show	VBN
cord-341690-h8fqijk5	138	11	in	in	IN
cord-341690-h8fqijk5	138	12	Figure	Figure	NNP
cord-341690-h8fqijk5	138	13	S1	S1	NNP
cord-341690-h8fqijk5	138	14	.	.	.
cord-341690-h8fqijk5	139	1	In	in	IN
cord-341690-h8fqijk5	139	2	order	order	NN
cord-341690-h8fqijk5	139	3	to	to	TO
cord-341690-h8fqijk5	139	4	study	study	VB
cord-341690-h8fqijk5	139	5	the	the	DT
cord-341690-h8fqijk5	139	6	role	role	NN
cord-341690-h8fqijk5	139	7	of	of	IN
cord-341690-h8fqijk5	139	8	RHO	rho	NN
cord-341690-h8fqijk5	139	9	-	-	HYPH
cord-341690-h8fqijk5	139	10	family	family	NN
cord-341690-h8fqijk5	139	11	-	-	HYPH
cord-341690-h8fqijk5	139	12	GTPases	gtpase	NNS
cord-341690-h8fqijk5	139	13	early	early	RB
cord-341690-h8fqijk5	139	14	in	in	IN
cord-341690-h8fqijk5	139	15	the	the	DT
cord-341690-h8fqijk5	139	16	entry	entry	NN
cord-341690-h8fqijk5	139	17	process	process	NN
cord-341690-h8fqijk5	139	18	of	of	IN
cord-341690-h8fqijk5	139	19	TGEV	TGEV	NNP
cord-341690-h8fqijk5	139	20	,	,	,
cord-341690-h8fqijk5	139	21	cells	cell	NNS
cord-341690-h8fqijk5	139	22	were	be	VBD
cord-341690-h8fqijk5	139	23	transfected	transfecte	VBN
cord-341690-h8fqijk5	139	24	with	with	IN
cord-341690-h8fqijk5	139	25	lentivirus	lentivirus	NN
cord-341690-h8fqijk5	139	26	constructs	construct	NNS
cord-341690-h8fqijk5	139	27	that	that	WDT
cord-341690-h8fqijk5	139	28	expressed	express	VBD
cord-341690-h8fqijk5	139	29	wild	wild	JJ
cord-341690-h8fqijk5	139	30	type	type	NN
cord-341690-h8fqijk5	139	31	,	,	,
cord-341690-h8fqijk5	139	32	constitutively	constitutively	RB
cord-341690-h8fqijk5	139	33	-	-	HYPH
cord-341690-h8fqijk5	139	34	activated	activate	VBN
cord-341690-h8fqijk5	139	35	,	,	,
cord-341690-h8fqijk5	139	36	or	or	CC
cord-341690-h8fqijk5	139	37	constitutively	constitutively	RB
cord-341690-h8fqijk5	139	38	-	-	HYPH
cord-341690-h8fqijk5	139	39	inactivated	inactivate	VBN
cord-341690-h8fqijk5	139	40	RHO	rho	NN
cord-341690-h8fqijk5	139	41	-	-	HYPH
cord-341690-h8fqijk5	139	42	family	family	NN
cord-341690-h8fqijk5	139	43	-	-	HYPH
cord-341690-h8fqijk5	139	44	GTPases	gtpase	NNS
cord-341690-h8fqijk5	139	45	.	.	.
cord-341690-h8fqijk5	140	1	The	the	DT
cord-341690-h8fqijk5	140	2	expression	expression	NN
cord-341690-h8fqijk5	140	3	of	of	IN
cord-341690-h8fqijk5	140	4	constitutively	constitutively	RB
cord-341690-h8fqijk5	140	5	activated	activate	VBN
cord-341690-h8fqijk5	140	6	L63RhoA	L63RhoA	NNP
cord-341690-h8fqijk5	140	7	,	,	,
cord-341690-h8fqijk5	140	8	L61Rac1	L61Rac1	NNP
cord-341690-h8fqijk5	140	9	,	,	,
cord-341690-h8fqijk5	140	10	and	and	CC
cord-341690-h8fqijk5	140	11	L61Cdc42	L61Cdc42	NNP
cord-341690-h8fqijk5	140	12	,	,	,
cord-341690-h8fqijk5	140	13	as	as	RB
cord-341690-h8fqijk5	140	14	well	well	RB
cord-341690-h8fqijk5	140	15	as	as	IN
cord-341690-h8fqijk5	140	16	constitutively	constitutively	RB
cord-341690-h8fqijk5	140	17	inactivated	inactivate	VBN
cord-341690-h8fqijk5	140	18	N17Rac1	N17Rac1	NNP
cord-341690-h8fqijk5	140	19	and	and	CC
cord-341690-h8fqijk5	140	20	N17Cdc42	N17Cdc42	NNP
cord-341690-h8fqijk5	140	21	,	,	,
cord-341690-h8fqijk5	140	22	decreased	decrease	VBD
cord-341690-h8fqijk5	140	23	TGEV	TGEV	NNP
cord-341690-h8fqijk5	140	24	entry	entry	NN
cord-341690-h8fqijk5	140	25	(	(	-LRB-
cord-341690-h8fqijk5	140	26	Figure	Figure	NNP
cord-341690-h8fqijk5	140	27	3D	3D	NNP
cord-341690-h8fqijk5	140	28	,	,	,
cord-341690-h8fqijk5	140	29	3E	3E	NNP
cord-341690-h8fqijk5	140	30	,	,	,
cord-341690-h8fqijk5	140	31	3F	3F	NNP
cord-341690-h8fqijk5	140	32	)	)	-RRB-
cord-341690-h8fqijk5	140	33	.	.	.
cord-341690-h8fqijk5	141	1	Additionally	additionally	RB
cord-341690-h8fqijk5	141	2	,	,	,
cord-341690-h8fqijk5	141	3	some	some	DT
cord-341690-h8fqijk5	141	4	RHO	rho	NN
cord-341690-h8fqijk5	141	5	-	-	HYPH
cord-341690-h8fqijk5	141	6	family	family	NN
cord-341690-h8fqijk5	141	7	-	-	HYPH
cord-341690-h8fqijk5	141	8	GTPases	gtpase	NNS
cord-341690-h8fqijk5	141	9	affected	affect	VBD
cord-341690-h8fqijk5	141	10	p	p	NN
cord-341690-h8fqijk5	141	11	-	-	HYPH
cord-341690-h8fqijk5	141	12	cofilin	cofilin	NN
cord-341690-h8fqijk5	141	13	level	level	NN
cord-341690-h8fqijk5	141	14	early	early	RB
cord-341690-h8fqijk5	141	15	in	in	IN
cord-341690-h8fqijk5	141	16	TGEV	TGEV	NNP
cord-341690-h8fqijk5	141	17	infection	infection	NN
cord-341690-h8fqijk5	142	1	,	,	,
cord-341690-h8fqijk5	142	2	the	the	DT
cord-341690-h8fqijk5	142	3	level	level	NN
cord-341690-h8fqijk5	142	4	of	of	IN
cord-341690-h8fqijk5	142	5	p	p	NN
cord-341690-h8fqijk5	142	6	-	-	:
cord-341690-h8fqijk5	142	7	cofilin	cofilin	NN
cord-341690-h8fqijk5	142	8	was	be	VBD
cord-341690-h8fqijk5	142	9	significantly	significantly	RB
cord-341690-h8fqijk5	142	10	inhibited	inhibit	VBN
cord-341690-h8fqijk5	142	11	in	in	IN
cord-341690-h8fqijk5	142	12	cells	cell	NNS
cord-341690-h8fqijk5	142	13	expressing	express	VBG
cord-341690-h8fqijk5	142	14	N17Rac1	N17Rac1	NNP
cord-341690-h8fqijk5	142	15	,	,	,
cord-341690-h8fqijk5	142	16	N17Cdc42	N17Cdc42	NNP
cord-341690-h8fqijk5	142	17	,	,	,
cord-341690-h8fqijk5	142	18	L61Rac1	L61Rac1	NNP
cord-341690-h8fqijk5	142	19	,	,	,
cord-341690-h8fqijk5	142	20	or	or	CC
cord-341690-h8fqijk5	142	21	L61Cdc42	L61Cdc42	NNS
cord-341690-h8fqijk5	142	22	,	,	,
cord-341690-h8fqijk5	142	23	but	but	CC
cord-341690-h8fqijk5	142	24	was	be	VBD
cord-341690-h8fqijk5	142	25	not	not	RB
cord-341690-h8fqijk5	142	26	affected	affect	VBN
cord-341690-h8fqijk5	142	27	in	in	IN
cord-341690-h8fqijk5	142	28	cells	cell	NNS
cord-341690-h8fqijk5	142	29	expressing	express	VBG
cord-341690-h8fqijk5	142	30	WT	WT	NNP
cord-341690-h8fqijk5	142	31	RhoA	RhoA	NNP
cord-341690-h8fqijk5	142	32	,	,	,
cord-341690-h8fqijk5	142	33	N19RhoA	N19RhoA	NNP
cord-341690-h8fqijk5	142	34	,	,	,
cord-341690-h8fqijk5	142	35	or	or	CC
cord-341690-h8fqijk5	142	36	L63RhoA	L63RhoA	NNP
cord-341690-h8fqijk5	142	37	(	(	-LRB-
cord-341690-h8fqijk5	142	38	Figure	figure	VB
cord-341690-h8fqijk5	142	39	 	 	_SP
cord-341690-h8fqijk5	142	40	3	3	CD
cord-341690-h8fqijk5	142	41	G	g	NN
cord-341690-h8fqijk5	142	42	,	,	,
cord-341690-h8fqijk5	142	43	3H	3H	NNP
cord-341690-h8fqijk5	142	44	,	,	,
cord-341690-h8fqijk5	142	45	3I	3i	CD
cord-341690-h8fqijk5	142	46	)	)	-RRB-
cord-341690-h8fqijk5	142	47	,	,	,
cord-341690-h8fqijk5	142	48	these	these	DT
cord-341690-h8fqijk5	142	49	data	datum	NNS
cord-341690-h8fqijk5	142	50	was	be	VBD
cord-341690-h8fqijk5	142	51	reinforced	reinforce	VBN
cord-341690-h8fqijk5	142	52	by	by	IN
cord-341690-h8fqijk5	142	53	results	result	NNS
cord-341690-h8fqijk5	142	54	obtained	obtain	VBN
cord-341690-h8fqijk5	142	55	using	use	VBG
cord-341690-h8fqijk5	142	56	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	142	57	drugs	drug	NNS
cord-341690-h8fqijk5	142	58	(	(	-LRB-
cord-341690-h8fqijk5	142	59	Y27632	Y27632	NNP
cord-341690-h8fqijk5	142	60	,	,	,
cord-341690-h8fqijk5	142	61	IPA-3	IPA-3	NNP
cord-341690-h8fqijk5	142	62	)	)	-RRB-
cord-341690-h8fqijk5	142	63	(	(	-LRB-
cord-341690-h8fqijk5	142	64	Figure	figure	NN
cord-341690-h8fqijk5	142	65	3C	3c	NN
cord-341690-h8fqijk5	142	66	)	)	-RRB-
cord-341690-h8fqijk5	142	67	.	.	.
cord-341690-h8fqijk5	143	1	All	all	DT
cord-341690-h8fqijk5	143	2	of	of	IN
cord-341690-h8fqijk5	143	3	these	these	DT
cord-341690-h8fqijk5	143	4	results	result	NNS
cord-341690-h8fqijk5	143	5	indicate	indicate	VBP
cord-341690-h8fqijk5	143	6	that	that	IN
cord-341690-h8fqijk5	143	7	RHO	rho	NN
cord-341690-h8fqijk5	143	8	-	-	HYPH
cord-341690-h8fqijk5	143	9	family	family	NN
cord-341690-h8fqijk5	143	10	-	-	HYPH
cord-341690-h8fqijk5	143	11	GTPases	gtpase	NNS
cord-341690-h8fqijk5	143	12	play	play	VBP
cord-341690-h8fqijk5	143	13	an	an	DT
cord-341690-h8fqijk5	143	14	important	important	JJ
cord-341690-h8fqijk5	143	15	role	role	NN
cord-341690-h8fqijk5	143	16	in	in	IN
cord-341690-h8fqijk5	143	17	TGEV	TGEV	NNP
cord-341690-h8fqijk5	143	18	entry	entry	NN
cord-341690-h8fqijk5	143	19	.	.	.
cord-341690-h8fqijk5	144	1	Specifically	specifically	RB
cord-341690-h8fqijk5	144	2	,	,	,
cord-341690-h8fqijk5	144	3	Rac1	Rac1	NNP
cord-341690-h8fqijk5	144	4	and	and	CC
cord-341690-h8fqijk5	144	5	Cdc42	Cdc42	NNP
cord-341690-h8fqijk5	144	6	are	be	VBP
cord-341690-h8fqijk5	144	7	involved	involve	VBN
cord-341690-h8fqijk5	144	8	in	in	IN
cord-341690-h8fqijk5	144	9	the	the	DT
cord-341690-h8fqijk5	144	10	regulation	regulation	NN
cord-341690-h8fqijk5	144	11	of	of	IN
cord-341690-h8fqijk5	144	12	cofilin	cofilin	NN
cord-341690-h8fqijk5	144	13	early	early	RB
cord-341690-h8fqijk5	144	14	in	in	IN
cord-341690-h8fqijk5	144	15	TGEV	TGEV	NNP
cord-341690-h8fqijk5	144	16	infection	infection	NN
cord-341690-h8fqijk5	144	17	,	,	,
cord-341690-h8fqijk5	144	18	while	while	IN
cord-341690-h8fqijk5	144	19	RhoA	RhoA	NNP
cord-341690-h8fqijk5	144	20	is	be	VBZ
cord-341690-h8fqijk5	144	21	not	not	RB
cord-341690-h8fqijk5	144	22	involved	involve	VBN
cord-341690-h8fqijk5	144	23	.	.	.
cord-341690-h8fqijk5	145	1	Neither	neither	DT
cord-341690-h8fqijk5	145	2	PI3	pi3	NN
cord-341690-h8fqijk5	145	3	K	K	NNP
cord-341690-h8fqijk5	145	4	modulation	modulation	NN
cord-341690-h8fqijk5	145	5	of	of	IN
cord-341690-h8fqijk5	145	6	the	the	DT
cord-341690-h8fqijk5	145	7	Rho	Rho	NNP
cord-341690-h8fqijk5	145	8	-	-	HYPH
cord-341690-h8fqijk5	145	9	GTPase	GTPase	NNP
cord-341690-h8fqijk5	145	10	family	family	NN
cord-341690-h8fqijk5	145	11	,	,	,
cord-341690-h8fqijk5	145	12	nor	nor	CC
cord-341690-h8fqijk5	145	13	the	the	DT
cord-341690-h8fqijk5	145	14	involvement	involvement	NN
cord-341690-h8fqijk5	145	15	of	of	IN
cord-341690-h8fqijk5	145	16	PI3K	PI3K	NNP
cord-341690-h8fqijk5	145	17	/	/	SYM
cord-341690-h8fqijk5	145	18	Akt	Akt	NNP
cord-341690-h8fqijk5	145	19	pathway	pathway	NN
cord-341690-h8fqijk5	145	20	early	early	RB
cord-341690-h8fqijk5	145	21	in	in	IN
cord-341690-h8fqijk5	145	22	coronavirus	coronavirus	NN
cord-341690-h8fqijk5	145	23	infection	infection	NN
cord-341690-h8fqijk5	145	24	,	,	,
cord-341690-h8fqijk5	145	25	have	have	VBP
cord-341690-h8fqijk5	145	26	been	be	VBN
cord-341690-h8fqijk5	145	27	demonstrated	demonstrate	VBN
cord-341690-h8fqijk5	145	28	conclusively	conclusively	RB
cord-341690-h8fqijk5	145	29	.	.	.
cord-341690-h8fqijk5	146	1	To	to	TO
cord-341690-h8fqijk5	146	2	investigate	investigate	VB
cord-341690-h8fqijk5	146	3	the	the	DT
cord-341690-h8fqijk5	146	4	role	role	NN
cord-341690-h8fqijk5	146	5	of	of	IN
cord-341690-h8fqijk5	146	6	PI3K	PI3K	NNP
cord-341690-h8fqijk5	146	7	/	/	SYM
cord-341690-h8fqijk5	146	8	Akt	Akt	NNP
cord-341690-h8fqijk5	146	9	pathway	pathway	NN
cord-341690-h8fqijk5	146	10	in	in	IN
cord-341690-h8fqijk5	146	11	TGEV	TGEV	NNP
cord-341690-h8fqijk5	146	12	entry	entry	NN
cord-341690-h8fqijk5	146	13	,	,	,
cord-341690-h8fqijk5	146	14	we	-PRON-	PRP
cord-341690-h8fqijk5	146	15	monitored	monitor	VBD
cord-341690-h8fqijk5	146	16	the	the	DT
cord-341690-h8fqijk5	146	17	level	level	NN
cord-341690-h8fqijk5	146	18	of	of	IN
cord-341690-h8fqijk5	146	19	p	p	NN
cord-341690-h8fqijk5	146	20	-	-	:
cord-341690-h8fqijk5	146	21	Akt	Akt	NNP
cord-341690-h8fqijk5	146	22	in	in	IN
cord-341690-h8fqijk5	146	23	cells	cell	NNS
cord-341690-h8fqijk5	146	24	shortly	shortly	RB
cord-341690-h8fqijk5	146	25	after	after	IN
cord-341690-h8fqijk5	146	26	infection	infection	NN
cord-341690-h8fqijk5	146	27	.	.	.
cord-341690-h8fqijk5	147	1	From	from	IN
cord-341690-h8fqijk5	147	2	10	10	CD
cord-341690-h8fqijk5	147	3	mpi	mpi	NN
cord-341690-h8fqijk5	147	4	to	to	IN
cord-341690-h8fqijk5	147	5	60	60	CD
cord-341690-h8fqijk5	147	6	mpi	mpi	NN
cord-341690-h8fqijk5	147	7	,	,	,
cord-341690-h8fqijk5	147	8	the	the	DT
cord-341690-h8fqijk5	147	9	level	level	NN
cord-341690-h8fqijk5	147	10	of	of	IN
cord-341690-h8fqijk5	147	11	p	p	NN
cord-341690-h8fqijk5	147	12	-	-	:
cord-341690-h8fqijk5	147	13	Akt	Akt	NNP
cord-341690-h8fqijk5	147	14	increased	increase	VBD
cord-341690-h8fqijk5	147	15	in	in	IN
cord-341690-h8fqijk5	147	16	TGEV	TGEV	NNP
cord-341690-h8fqijk5	147	17	infected	infect	VBN
cord-341690-h8fqijk5	147	18	cells	cell	NNS
cord-341690-h8fqijk5	147	19	(	(	-LRB-
cord-341690-h8fqijk5	147	20	Figure	figure	NN
cord-341690-h8fqijk5	147	21	4A	4a	CD
cord-341690-h8fqijk5	147	22	)	)	-RRB-
cord-341690-h8fqijk5	147	23	.	.	.
cord-341690-h8fqijk5	148	1	In	in	IN
cord-341690-h8fqijk5	148	2	cells	cell	NNS
cord-341690-h8fqijk5	148	3	pretreated	pretreate	VBN
cord-341690-h8fqijk5	148	4	with	with	IN
cord-341690-h8fqijk5	148	5	LY294002	LY294002	NNP
cord-341690-h8fqijk5	148	6	,	,	,
cord-341690-h8fqijk5	148	7	a	a	DT
cord-341690-h8fqijk5	148	8	highly	highly	RB
cord-341690-h8fqijk5	148	9	specific	specific	JJ
cord-341690-h8fqijk5	148	10	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	148	11	of	of	IN
cord-341690-h8fqijk5	148	12	PI3	PI3	NNP
cord-341690-h8fqijk5	148	13	K	K	NNP
cord-341690-h8fqijk5	148	14	,	,	,
cord-341690-h8fqijk5	148	15	virus	virus	NN
cord-341690-h8fqijk5	148	16	binding	binding	NN
cord-341690-h8fqijk5	148	17	was	be	VBD
cord-341690-h8fqijk5	148	18	unaffected	unaffected	JJ
cord-341690-h8fqijk5	148	19	,	,	,
cord-341690-h8fqijk5	148	20	but	but	CC
cord-341690-h8fqijk5	148	21	TGEV	TGEV	NNP
cord-341690-h8fqijk5	148	22	entry	entry	NN
cord-341690-h8fqijk5	148	23	was	be	VBD
cord-341690-h8fqijk5	148	24	reduced	reduce	VBN
cord-341690-h8fqijk5	148	25	40	40	CD
cord-341690-h8fqijk5	148	26	%	%	NN
cord-341690-h8fqijk5	148	27	compared	compare	VBN
cord-341690-h8fqijk5	148	28	with	with	IN
cord-341690-h8fqijk5	148	29	untreated	untreated	JJ
cord-341690-h8fqijk5	148	30	cells	cell	NNS
cord-341690-h8fqijk5	148	31	(	(	-LRB-
cord-341690-h8fqijk5	148	32	Figure	figure	NN
cord-341690-h8fqijk5	148	33	 	 	_SP
cord-341690-h8fqijk5	148	34	4B	4b	CD
cord-341690-h8fqijk5	148	35	)	)	-RRB-
cord-341690-h8fqijk5	148	36	.	.	.
cord-341690-h8fqijk5	149	1	Examination	examination	NN
cord-341690-h8fqijk5	149	2	by	by	IN
cord-341690-h8fqijk5	149	3	confocal	confocal	JJ
cord-341690-h8fqijk5	149	4	fluorescence	fluorescence	NN
cord-341690-h8fqijk5	149	5	microscopy	microscopy	NNS
cord-341690-h8fqijk5	149	6	demonstrated	demonstrate	VBD
cord-341690-h8fqijk5	149	7	that	that	IN
cord-341690-h8fqijk5	149	8	LY294002	ly294002	PRP
cord-341690-h8fqijk5	149	9	inhibited	inhibit	VBD
cord-341690-h8fqijk5	149	10	the	the	DT
cord-341690-h8fqijk5	149	11	destruction	destruction	NN
cord-341690-h8fqijk5	149	12	of	of	IN
cord-341690-h8fqijk5	149	13	F	F	NNP
cord-341690-h8fqijk5	149	14	-	-	HYPH
cord-341690-h8fqijk5	149	15	actin	actin	NNP
cord-341690-h8fqijk5	149	16	early	early	RB
cord-341690-h8fqijk5	149	17	in	in	IN
cord-341690-h8fqijk5	149	18	TGEV	TGEV	NNP
cord-341690-h8fqijk5	149	19	infection	infection	NN
cord-341690-h8fqijk5	149	20	(	(	-LRB-
cord-341690-h8fqijk5	149	21	Figure	figure	NN
cord-341690-h8fqijk5	149	22	4C	4c	CD
cord-341690-h8fqijk5	149	23	)	)	-RRB-
cord-341690-h8fqijk5	149	24	.	.	.
cord-341690-h8fqijk5	150	1	We	-PRON-	PRP
cord-341690-h8fqijk5	150	2	previously	previously	RB
cord-341690-h8fqijk5	150	3	have	have	VBP
cord-341690-h8fqijk5	150	4	showed	show	VBN
cord-341690-h8fqijk5	150	5	that	that	IN
cord-341690-h8fqijk5	150	6	attenuated	attenuate	VBN
cord-341690-h8fqijk5	150	7	TGEV	TGEV	NNS
cord-341690-h8fqijk5	150	8	(	(	-LRB-
cord-341690-h8fqijk5	150	9	STC3	STC3	NNP
cord-341690-h8fqijk5	150	10	strain	strain	NN
cord-341690-h8fqijk5	150	11	)	)	-RRB-
cord-341690-h8fqijk5	150	12	and	and	CC
cord-341690-h8fqijk5	150	13	PEDV	PEDV	NNP
cord-341690-h8fqijk5	150	14	(	(	-LRB-
cord-341690-h8fqijk5	150	15	CV777	cv777	CD
cord-341690-h8fqijk5	150	16	strain	strain	NN
cord-341690-h8fqijk5	150	17	)	)	-RRB-
cord-341690-h8fqijk5	150	18	could	could	MD
cord-341690-h8fqijk5	150	19	regulate	regulate	VB
cord-341690-h8fqijk5	150	20	the	the	DT
cord-341690-h8fqijk5	150	21	F	F	NNP
cord-341690-h8fqijk5	150	22	-	-	HYPH
cord-341690-h8fqijk5	150	23	actin	actin	NNP
cord-341690-h8fqijk5	150	24	via	via	IN
cord-341690-h8fqijk5	150	25	the	the	DT
cord-341690-h8fqijk5	150	26	MAPK	MAPK	NNP
cord-341690-h8fqijk5	150	27	pathways	pathway	NNS
cord-341690-h8fqijk5	150	28	[	[	-LRB-
cord-341690-h8fqijk5	150	29	23	23	CD
cord-341690-h8fqijk5	150	30	]	]	-RRB-
cord-341690-h8fqijk5	150	31	.	.	.
cord-341690-h8fqijk5	151	1	In	in	IN
cord-341690-h8fqijk5	151	2	this	this	DT
cord-341690-h8fqijk5	151	3	study	study	NN
cord-341690-h8fqijk5	151	4	,	,	,
cord-341690-h8fqijk5	151	5	we	-PRON-	PRP
cord-341690-h8fqijk5	151	6	found	find	VBD
cord-341690-h8fqijk5	151	7	that	that	IN
cord-341690-h8fqijk5	151	8	TGEV	TGEV	NNP
cord-341690-h8fqijk5	151	9	infection	infection	NN
cord-341690-h8fqijk5	151	10	induced	induce	VBD
cord-341690-h8fqijk5	151	11	the	the	DT
cord-341690-h8fqijk5	151	12	activity	activity	NN
cord-341690-h8fqijk5	151	13	of	of	IN
cord-341690-h8fqijk5	151	14	ERK1/2	ERK1/2	NNP
cord-341690-h8fqijk5	151	15	at	at	IN
cord-341690-h8fqijk5	151	16	5	5	CD
cord-341690-h8fqijk5	151	17	mpi	mpi	NNP
cord-341690-h8fqijk5	151	18	and	and	CC
cord-341690-h8fqijk5	151	19	increased	increase	VBD
cord-341690-h8fqijk5	151	20	it	-PRON-	PRP
cord-341690-h8fqijk5	151	21	thereafter	thereafter	RB
cord-341690-h8fqijk5	151	22	(	(	-LRB-
cord-341690-h8fqijk5	151	23	Figure	figure	NN
cord-341690-h8fqijk5	151	24	4D	4d	CD
cord-341690-h8fqijk5	151	25	)	)	-RRB-
cord-341690-h8fqijk5	151	26	.	.	.
cord-341690-h8fqijk5	152	1	U0126	U0126	NNP
cord-341690-h8fqijk5	152	2	,	,	,
cord-341690-h8fqijk5	152	3	a	a	DT
cord-341690-h8fqijk5	152	4	specific	specific	JJ
cord-341690-h8fqijk5	152	5	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	152	6	of	of	IN
cord-341690-h8fqijk5	152	7	MEK1/2	MEK1/2	NNP
cord-341690-h8fqijk5	152	8	,	,	,
cord-341690-h8fqijk5	152	9	inhibited	inhibited	JJ
cord-341690-h8fqijk5	152	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	152	11	entry	entry	NN
cord-341690-h8fqijk5	152	12	in	in	IN
cord-341690-h8fqijk5	152	13	a	a	DT
cord-341690-h8fqijk5	152	14	dose	dose	NN
cord-341690-h8fqijk5	152	15	dependent	dependent	JJ
cord-341690-h8fqijk5	152	16	manner	manner	NN
cord-341690-h8fqijk5	152	17	but	but	CC
cord-341690-h8fqijk5	152	18	did	do	VBD
cord-341690-h8fqijk5	152	19	not	not	RB
cord-341690-h8fqijk5	152	20	affect	affect	VB
cord-341690-h8fqijk5	152	21	the	the	DT
cord-341690-h8fqijk5	152	22	ability	ability	NN
cord-341690-h8fqijk5	152	23	of	of	IN
cord-341690-h8fqijk5	152	24	the	the	DT
cord-341690-h8fqijk5	152	25	virus	virus	NN
cord-341690-h8fqijk5	152	26	to	to	TO
cord-341690-h8fqijk5	152	27	bind	bind	VB
cord-341690-h8fqijk5	152	28	to	to	IN
cord-341690-h8fqijk5	152	29	cells	cell	NNS
cord-341690-h8fqijk5	152	30	(	(	-LRB-
cord-341690-h8fqijk5	152	31	Figure	figure	NN
cord-341690-h8fqijk5	152	32	4E	4e	NN
cord-341690-h8fqijk5	152	33	)	)	-RRB-
cord-341690-h8fqijk5	152	34	.	.	.
cord-341690-h8fqijk5	153	1	U0126	U0126	NNP
cord-341690-h8fqijk5	153	2	also	also	RB
cord-341690-h8fqijk5	153	3	inhibited	inhibit	VBD
cord-341690-h8fqijk5	153	4	the	the	DT
cord-341690-h8fqijk5	153	5	destruction	destruction	NN
cord-341690-h8fqijk5	153	6	of	of	IN
cord-341690-h8fqijk5	153	7	F	f	NN
cord-341690-h8fqijk5	153	8	-	-	HYPH
cord-341690-h8fqijk5	153	9	actin	actin	NN
cord-341690-h8fqijk5	153	10	by	by	IN
cord-341690-h8fqijk5	153	11	TGEV	TGEV	NNP
cord-341690-h8fqijk5	153	12	infection	infection	NN
cord-341690-h8fqijk5	153	13	,	,	,
cord-341690-h8fqijk5	153	14	as	as	IN
cord-341690-h8fqijk5	153	15	observed	observe	VBN
cord-341690-h8fqijk5	153	16	when	when	WRB
cord-341690-h8fqijk5	153	17	cells	cell	NNS
cord-341690-h8fqijk5	153	18	were	be	VBD
cord-341690-h8fqijk5	153	19	examined	examine	VBN
cord-341690-h8fqijk5	153	20	by	by	IN
cord-341690-h8fqijk5	153	21	confocal	confocal	JJ
cord-341690-h8fqijk5	153	22	fluorescence	fluorescence	NN
cord-341690-h8fqijk5	153	23	microscopy	microscopy	NN
cord-341690-h8fqijk5	153	24	(	(	-LRB-
cord-341690-h8fqijk5	153	25	Figure	figure	NN
cord-341690-h8fqijk5	153	26	4C	4c	CD
cord-341690-h8fqijk5	153	27	)	)	-RRB-
cord-341690-h8fqijk5	153	28	.	.	.
cord-341690-h8fqijk5	154	1	The	the	DT
cord-341690-h8fqijk5	154	2	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	154	3	of	of	IN
cord-341690-h8fqijk5	154	4	Akt	Akt	NNP
cord-341690-h8fqijk5	154	5	,	,	,
cord-341690-h8fqijk5	154	6	LIMK	LIMK	NNP
cord-341690-h8fqijk5	154	7	and	and	CC
cord-341690-h8fqijk5	154	8	cofilin	cofilin	NNP
cord-341690-h8fqijk5	154	9	were	be	VBD
cord-341690-h8fqijk5	154	10	inhibited	inhibit	VBN
cord-341690-h8fqijk5	154	11	when	when	WRB
cord-341690-h8fqijk5	154	12	cells	cell	NNS
cord-341690-h8fqijk5	154	13	were	be	VBD
cord-341690-h8fqijk5	154	14	treated	treat	VBN
cord-341690-h8fqijk5	154	15	with	with	IN
cord-341690-h8fqijk5	154	16	PI3	PI3	NNP
cord-341690-h8fqijk5	154	17	K	K	NNP
cord-341690-h8fqijk5	154	18	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	154	19	LY294002	LY294002	NNP
cord-341690-h8fqijk5	154	20	(	(	-LRB-
cord-341690-h8fqijk5	154	21	Figure	figure	NN
cord-341690-h8fqijk5	154	22	4F	4f	CD
cord-341690-h8fqijk5	154	23	)	)	-RRB-
cord-341690-h8fqijk5	154	24	,	,	,
cord-341690-h8fqijk5	154	25	suggesting	suggest	VBG
cord-341690-h8fqijk5	154	26	that	that	IN
cord-341690-h8fqijk5	154	27	the	the	DT
cord-341690-h8fqijk5	154	28	PI3K	PI3K	NNP
cord-341690-h8fqijk5	154	29	/	/	SYM
cord-341690-h8fqijk5	154	30	Akt	Akt	NNP
cord-341690-h8fqijk5	154	31	pathway	pathway	NN
cord-341690-h8fqijk5	154	32	is	be	VBZ
cord-341690-h8fqijk5	154	33	involved	involve	VBN
cord-341690-h8fqijk5	154	34	in	in	IN
cord-341690-h8fqijk5	154	35	the	the	DT
cord-341690-h8fqijk5	154	36	regulation	regulation	NN
cord-341690-h8fqijk5	154	37	of	of	IN
cord-341690-h8fqijk5	154	38	actin	actin	NN
cord-341690-h8fqijk5	154	39	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	154	40	by	by	IN
cord-341690-h8fqijk5	154	41	cofilin	cofilin	NNP
cord-341690-h8fqijk5	154	42	.	.	.
cord-341690-h8fqijk5	155	1	ERK1/2	ERK1/2	NNP
cord-341690-h8fqijk5	156	1	,	,	,
cord-341690-h8fqijk5	156	2	LIMK	LIMK	NNP
cord-341690-h8fqijk5	156	3	and	and	CC
cord-341690-h8fqijk5	156	4	cofilin	cofilin	NN
cord-341690-h8fqijk5	156	5	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	156	6	were	be	VBD
cord-341690-h8fqijk5	156	7	inhibited	inhibit	VBN
cord-341690-h8fqijk5	156	8	when	when	WRB
cord-341690-h8fqijk5	156	9	cells	cell	NNS
cord-341690-h8fqijk5	156	10	were	be	VBD
cord-341690-h8fqijk5	156	11	treated	treat	VBN
cord-341690-h8fqijk5	156	12	with	with	IN
cord-341690-h8fqijk5	156	13	MEK1/2	MEK1/2	NNP
cord-341690-h8fqijk5	157	1	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	157	2	U0126	U0126	NNP
cord-341690-h8fqijk5	157	3	,	,	,
cord-341690-h8fqijk5	157	4	but	but	CC
cord-341690-h8fqijk5	158	1	the	the	DT
cord-341690-h8fqijk5	158	2	activation	activation	NN
cord-341690-h8fqijk5	158	3	of	of	IN
cord-341690-h8fqijk5	158	4	ERK1/2	ERK1/2	NNP
cord-341690-h8fqijk5	158	5	was	be	VBD
cord-341690-h8fqijk5	158	6	not	not	RB
cord-341690-h8fqijk5	158	7	inhibited	inhibit	VBN
cord-341690-h8fqijk5	158	8	by	by	IN
cord-341690-h8fqijk5	158	9	LY294002	LY294002	NNP
cord-341690-h8fqijk5	158	10	.	.	.
cord-341690-h8fqijk5	159	1	These	these	DT
cord-341690-h8fqijk5	159	2	results	result	NNS
cord-341690-h8fqijk5	159	3	indicate	indicate	VBP
cord-341690-h8fqijk5	159	4	that	that	IN
cord-341690-h8fqijk5	159	5	the	the	DT
cord-341690-h8fqijk5	159	6	MEK	MEK	NNP
cord-341690-h8fqijk5	159	7	/	/	SYM
cord-341690-h8fqijk5	159	8	ERK	ERK	NNP
cord-341690-h8fqijk5	159	9	pathway	pathway	NN
cord-341690-h8fqijk5	159	10	also	also	RB
cord-341690-h8fqijk5	159	11	involve	involve	VBP
cord-341690-h8fqijk5	159	12	in	in	IN
cord-341690-h8fqijk5	159	13	the	the	DT
cord-341690-h8fqijk5	159	14	regulation	regulation	NN
cord-341690-h8fqijk5	159	15	of	of	IN
cord-341690-h8fqijk5	159	16	the	the	DT
cord-341690-h8fqijk5	159	17	actin	actin	NN
cord-341690-h8fqijk5	159	18	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	159	19	by	by	IN
cord-341690-h8fqijk5	159	20	cofilin	cofilin	NNP
cord-341690-h8fqijk5	159	21	,	,	,
cord-341690-h8fqijk5	159	22	but	but	CC
cord-341690-h8fqijk5	159	23	it	-PRON-	PRP
cord-341690-h8fqijk5	159	24	is	be	VBZ
cord-341690-h8fqijk5	159	25	not	not	RB
cord-341690-h8fqijk5	159	26	activated	activate	VBN
cord-341690-h8fqijk5	159	27	by	by	IN
cord-341690-h8fqijk5	159	28	PI3K	PI3K	NNP
cord-341690-h8fqijk5	159	29	/	/	SYM
cord-341690-h8fqijk5	159	30	Akt	Akt	NNP
cord-341690-h8fqijk5	159	31	pathway	pathway	NN
cord-341690-h8fqijk5	159	32	.	.	.
cord-341690-h8fqijk5	160	1	Figure	figure	NN
cord-341690-h8fqijk5	160	2	6	6	CD
cord-341690-h8fqijk5	160	3	:	:	:
cord-341690-h8fqijk5	161	1	EGFR	EGFR	NNP
cord-341690-h8fqijk5	161	2	is	be	VBZ
cord-341690-h8fqijk5	161	3	involved	involve	VBN
cord-341690-h8fqijk5	161	4	in	in	IN
cord-341690-h8fqijk5	161	5	TGEV	TGEV	NNP
cord-341690-h8fqijk5	161	6	entry	entry	NN
cord-341690-h8fqijk5	161	7	.	.	.
cord-341690-h8fqijk5	162	1	A.	A.	NNP
cord-341690-h8fqijk5	162	2	TGEV	TGEV	NNP
cord-341690-h8fqijk5	162	3	is	be	VBZ
cord-341690-h8fqijk5	162	4	co	co	JJ
cord-341690-h8fqijk5	162	5	-	-	VBN
cord-341690-h8fqijk5	162	6	localized	localize	VBN
cord-341690-h8fqijk5	162	7	with	with	IN
cord-341690-h8fqijk5	162	8	EGFR	EGFR	NNP
cord-341690-h8fqijk5	162	9	.	.	.
cord-341690-h8fqijk5	163	1	After	after	IN
cord-341690-h8fqijk5	163	2	10	10	CD
cord-341690-h8fqijk5	163	3	mpi	mpi	NNS
cord-341690-h8fqijk5	163	4	,	,	,
cord-341690-h8fqijk5	163	5	cells	cell	NNS
cord-341690-h8fqijk5	163	6	were	be	VBD
cord-341690-h8fqijk5	163	7	fixed	fix	VBN
cord-341690-h8fqijk5	163	8	and	and	CC
cord-341690-h8fqijk5	163	9	stained	stain	VBN
cord-341690-h8fqijk5	163	10	with	with	IN
cord-341690-h8fqijk5	163	11	mouse	mouse	NN
cord-341690-h8fqijk5	163	12	anti	anti	JJ
cord-341690-h8fqijk5	163	13	-	-	JJ
cord-341690-h8fqijk5	163	14	TGEV	tgev	JJ
cord-341690-h8fqijk5	163	15	mAb	mAb	NNS
cord-341690-h8fqijk5	163	16	,	,	,
cord-341690-h8fqijk5	163	17	followed	follow	VBN
cord-341690-h8fqijk5	163	18	by	by	IN
cord-341690-h8fqijk5	163	19	DyLight	DyLight	NNP
cord-341690-h8fqijk5	163	20	488-conjugated	488-conjugated	CD
cord-341690-h8fqijk5	163	21	goat	goat	NNP
cord-341690-h8fqijk5	163	22	anti	anti	JJ
cord-341690-h8fqijk5	163	23	-	-	JJ
cord-341690-h8fqijk5	163	24	mouse	mouse	JJ
cord-341690-h8fqijk5	163	25	IgG	igg	NN
cord-341690-h8fqijk5	163	26	and	and	CC
cord-341690-h8fqijk5	163	27	anti	anti	JJ
cord-341690-h8fqijk5	163	28	-	-	JJ
cord-341690-h8fqijk5	163	29	p	p	JJ
cord-341690-h8fqijk5	163	30	-	-	HYPH
cord-341690-h8fqijk5	163	31	EGFR	egfr	NN
cord-341690-h8fqijk5	163	32	pAb	pab	NN
cord-341690-h8fqijk5	163	33	,	,	,
cord-341690-h8fqijk5	163	34	followed	follow	VBN
cord-341690-h8fqijk5	163	35	by	by	IN
cord-341690-h8fqijk5	163	36	Dylight	Dylight	NNP
cord-341690-h8fqijk5	163	37	594-conjugated	594-conjugated	CD
cord-341690-h8fqijk5	163	38	goat	goat	NN
cord-341690-h8fqijk5	163	39	anti	anti	JJ
cord-341690-h8fqijk5	163	40	-	-	JJ
cord-341690-h8fqijk5	163	41	rabbit	rabbit	JJ
cord-341690-h8fqijk5	163	42	IgG.	IgG.	NNP
cord-341690-h8fqijk5	163	43	Cells	cell	NNS
cord-341690-h8fqijk5	163	44	were	be	VBD
cord-341690-h8fqijk5	163	45	examined	examine	VBN
cord-341690-h8fqijk5	163	46	by	by	IN
cord-341690-h8fqijk5	163	47	IF	if	NN
cord-341690-h8fqijk5	163	48	microscopy	microscopy	NNS
cord-341690-h8fqijk5	163	49	.	.	.
cord-341690-h8fqijk5	164	1	B.	B.	NNP
cord-341690-h8fqijk5	165	1	The	the	DT
cord-341690-h8fqijk5	165	2	RTK	RTK	NNP
cord-341690-h8fqijk5	165	3	specific	specific	JJ
cord-341690-h8fqijk5	165	4	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	165	5	,	,	,
cord-341690-h8fqijk5	165	6	genistein	genistein	NNP
cord-341690-h8fqijk5	165	7	(	(	-LRB-
cord-341690-h8fqijk5	165	8	Gen	Gen	NNP
cord-341690-h8fqijk5	165	9	)	)	-RRB-
cord-341690-h8fqijk5	165	10	,	,	,
cord-341690-h8fqijk5	165	11	inhibits	inhibit	VBZ
cord-341690-h8fqijk5	165	12	TGEV	TGEV	NNP
cord-341690-h8fqijk5	165	13	entry	entry	NN
cord-341690-h8fqijk5	165	14	in	in	IN
cord-341690-h8fqijk5	165	15	a	a	DT
cord-341690-h8fqijk5	165	16	dose	dose	NN
cord-341690-h8fqijk5	165	17	dependent	dependent	JJ
cord-341690-h8fqijk5	165	18	manner	manner	NN
cord-341690-h8fqijk5	165	19	.	.	.
cord-341690-h8fqijk5	166	1	Cells	cell	NNS
cord-341690-h8fqijk5	166	2	were	be	VBD
cord-341690-h8fqijk5	166	3	pretreated	pretreate	VBN
cord-341690-h8fqijk5	166	4	with	with	IN
cord-341690-h8fqijk5	166	5	different	different	JJ
cord-341690-h8fqijk5	166	6	concentrations	concentration	NNS
cord-341690-h8fqijk5	166	7	of	of	IN
cord-341690-h8fqijk5	166	8	genistein	genistein	NNP
cord-341690-h8fqijk5	166	9	.	.	.
cord-341690-h8fqijk5	167	1	TGEV	TGEV	NNP
cord-341690-h8fqijk5	167	2	binding	bind	VBG
cord-341690-h8fqijk5	167	3	and	and	CC
cord-341690-h8fqijk5	167	4	entry	entry	NN
cord-341690-h8fqijk5	167	5	assays	assay	NNS
cord-341690-h8fqijk5	167	6	are	be	VBP
cord-341690-h8fqijk5	167	7	described	describe	VBN
cord-341690-h8fqijk5	167	8	in	in	IN
cord-341690-h8fqijk5	167	9	materials	material	NNS
cord-341690-h8fqijk5	167	10	and	and	CC
cord-341690-h8fqijk5	167	11	methods	method	NNS
cord-341690-h8fqijk5	167	12	.	.	.
cord-341690-h8fqijk5	168	1	C.	C.	NNP
cord-341690-h8fqijk5	168	2	and	and	CC
cord-341690-h8fqijk5	168	3	D.	D.	NNP
cord-341690-h8fqijk5	169	1	The	the	DT
cord-341690-h8fqijk5	169	2	EGFR	EGFR	NNP
cord-341690-h8fqijk5	169	3	specific	specific	JJ
cord-341690-h8fqijk5	169	4	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	169	5	,	,	,
cord-341690-h8fqijk5	169	6	AG1478	ag1478	NN
cord-341690-h8fqijk5	169	7	,	,	,
cord-341690-h8fqijk5	169	8	inhibits	inhibit	VBZ
cord-341690-h8fqijk5	169	9	TGEV	TGEV	NNP
cord-341690-h8fqijk5	169	10	entry	entry	NN
cord-341690-h8fqijk5	169	11	.	.	.
cord-341690-h8fqijk5	170	1	IPEC	IPEC	NNP
cord-341690-h8fqijk5	170	2	-	-	HYPH
cord-341690-h8fqijk5	170	3	J2	j2	NN
cord-341690-h8fqijk5	170	4	cells	cell	NNS
cord-341690-h8fqijk5	170	5	were	be	VBD
cord-341690-h8fqijk5	170	6	pretreated	pretreate	VBN
cord-341690-h8fqijk5	170	7	with	with	IN
cord-341690-h8fqijk5	170	8	AG1478	ag1478	NN
cord-341690-h8fqijk5	170	9	for	for	IN
cord-341690-h8fqijk5	170	10	1	1	CD
cord-341690-h8fqijk5	170	11	h	h	NN
cord-341690-h8fqijk5	170	12	at	at	IN
cord-341690-h8fqijk5	170	13	37	37	CD
cord-341690-h8fqijk5	170	14	°	°	NN
cord-341690-h8fqijk5	170	15	C	c	NN
cord-341690-h8fqijk5	170	16	.	.	.
cord-341690-h8fqijk5	171	1	Alternatively	alternatively	RB
cord-341690-h8fqijk5	171	2	,	,	,
cord-341690-h8fqijk5	171	3	IPEC	IPEC	NNP
cord-341690-h8fqijk5	171	4	-	-	HYPH
cord-341690-h8fqijk5	171	5	J2	j2	NN
cord-341690-h8fqijk5	171	6	cells	cell	NNS
cord-341690-h8fqijk5	171	7	were	be	VBD
cord-341690-h8fqijk5	171	8	incubated	incubate	VBN
cord-341690-h8fqijk5	171	9	with	with	IN
cord-341690-h8fqijk5	171	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	171	11	at	at	IN
cord-341690-h8fqijk5	171	12	4	4	CD
cord-341690-h8fqijk5	171	13	°	°	NN
cord-341690-h8fqijk5	171	14	C	c	NN
cord-341690-h8fqijk5	171	15	for	for	IN
cord-341690-h8fqijk5	171	16	1	1	CD
cord-341690-h8fqijk5	171	17	h	h	NN
cord-341690-h8fqijk5	171	18	,	,	,
cord-341690-h8fqijk5	171	19	unbound	unbound	JJ
cord-341690-h8fqijk5	171	20	viruses	virus	NNS
cord-341690-h8fqijk5	171	21	were	be	VBD
cord-341690-h8fqijk5	171	22	removed	remove	VBN
cord-341690-h8fqijk5	171	23	,	,	,
cord-341690-h8fqijk5	171	24	cells	cell	NNS
cord-341690-h8fqijk5	171	25	were	be	VBD
cord-341690-h8fqijk5	171	26	shifted	shift	VBN
cord-341690-h8fqijk5	171	27	to	to	IN
cord-341690-h8fqijk5	171	28	37	37	CD
cord-341690-h8fqijk5	171	29	°	°	NN
cord-341690-h8fqijk5	171	30	C	c	NN
cord-341690-h8fqijk5	171	31	,	,	,
cord-341690-h8fqijk5	171	32	and	and	CC
cord-341690-h8fqijk5	171	33	AG1478	AG1478	NNP
cord-341690-h8fqijk5	171	34	was	be	VBD
cord-341690-h8fqijk5	171	35	added	add	VBN
cord-341690-h8fqijk5	171	36	at	at	IN
cord-341690-h8fqijk5	171	37	0	0	CD
cord-341690-h8fqijk5	171	38	-	-	SYM
cord-341690-h8fqijk5	171	39	20	20	CD
cord-341690-h8fqijk5	171	40	mpi	mpi	NN
cord-341690-h8fqijk5	171	41	,	,	,
cord-341690-h8fqijk5	171	42	20	20	CD
cord-341690-h8fqijk5	171	43	-	-	SYM
cord-341690-h8fqijk5	171	44	40	40	CD
cord-341690-h8fqijk5	171	45	mpi	mpi	NN
cord-341690-h8fqijk5	171	46	,	,	,
cord-341690-h8fqijk5	171	47	and	and	CC
cord-341690-h8fqijk5	171	48	40	40	CD
cord-341690-h8fqijk5	171	49	-	-	SYM
cord-341690-h8fqijk5	171	50	60	60	CD
cord-341690-h8fqijk5	171	51	mpi	mpi	NN
cord-341690-h8fqijk5	171	52	.	.	.
cord-341690-h8fqijk5	172	1	E.	E.	NNP
cord-341690-h8fqijk5	173	1	The	the	DT
cord-341690-h8fqijk5	173	2	activation	activation	NN
cord-341690-h8fqijk5	173	3	of	of	IN
cord-341690-h8fqijk5	173	4	EGFR	EGFR	NNP
cord-341690-h8fqijk5	173	5	promotes	promote	VBZ
cord-341690-h8fqijk5	173	6	TGEV	TGEV	NNP
cord-341690-h8fqijk5	173	7	entry	entry	NN
cord-341690-h8fqijk5	173	8	.	.	.
cord-341690-h8fqijk5	174	1	Serum	serum	NN
cord-341690-h8fqijk5	174	2	-	-	HYPH
cord-341690-h8fqijk5	174	3	starved	starve	VBN
cord-341690-h8fqijk5	174	4	IPEC	IPEC	NNP
cord-341690-h8fqijk5	174	5	-	-	HYPH
cord-341690-h8fqijk5	174	6	J2	j2	NN
cord-341690-h8fqijk5	174	7	cells	cell	NNS
cord-341690-h8fqijk5	174	8	were	be	VBD
cord-341690-h8fqijk5	174	9	pretreated	pretreate	VBN
cord-341690-h8fqijk5	174	10	with	with	IN
cord-341690-h8fqijk5	174	11	different	different	JJ
cord-341690-h8fqijk5	174	12	low	low	JJ
cord-341690-h8fqijk5	174	13	concentrations	concentration	NNS
cord-341690-h8fqijk5	174	14	of	of	IN
cord-341690-h8fqijk5	174	15	EGF	EGF	NNP
cord-341690-h8fqijk5	174	16	at	at	IN
cord-341690-h8fqijk5	174	17	37	37	CD
cord-341690-h8fqijk5	174	18	°	°	NN
cord-341690-h8fqijk5	174	19	C	c	NN
cord-341690-h8fqijk5	174	20	for	for	IN
cord-341690-h8fqijk5	174	21	1	1	CD
cord-341690-h8fqijk5	174	22	h	h	NN
cord-341690-h8fqijk5	174	23	,	,	,
cord-341690-h8fqijk5	174	24	cells	cell	NNS
cord-341690-h8fqijk5	174	25	were	be	VBD
cord-341690-h8fqijk5	174	26	infected	infect	VBN
cord-341690-h8fqijk5	174	27	with	with	IN
cord-341690-h8fqijk5	174	28	TGEV	TGEV	NNP
cord-341690-h8fqijk5	174	29	for	for	IN
cord-341690-h8fqijk5	174	30	1	1	CD
cord-341690-h8fqijk5	174	31	h	h	NN
cord-341690-h8fqijk5	174	32	and	and	CC
cord-341690-h8fqijk5	174	33	entry	entry	NN
cord-341690-h8fqijk5	174	34	of	of	IN
cord-341690-h8fqijk5	174	35	TGEV	TGEV	NNP
cord-341690-h8fqijk5	174	36	was	be	VBD
cord-341690-h8fqijk5	174	37	evaluated	evaluate	VBN
cord-341690-h8fqijk5	174	38	by	by	IN
cord-341690-h8fqijk5	174	39	real	real	JJ
cord-341690-h8fqijk5	174	40	-	-	HYPH
cord-341690-h8fqijk5	174	41	time	time	NN
cord-341690-h8fqijk5	174	42	PCR	PCR	NNP
cord-341690-h8fqijk5	174	43	.	.	.
cord-341690-h8fqijk5	175	1	F.	F.	NNP
cord-341690-h8fqijk5	176	1	The	the	DT
cord-341690-h8fqijk5	176	2	internalized	internalize	VBN
cord-341690-h8fqijk5	176	3	of	of	IN
cord-341690-h8fqijk5	176	4	EGFR	EGFR	NNP
cord-341690-h8fqijk5	176	5	inhibits	inhibit	VBZ
cord-341690-h8fqijk5	176	6	TGEV	TGEV	NNP
cord-341690-h8fqijk5	176	7	entry	entry	NN
cord-341690-h8fqijk5	176	8	.	.	.
cord-341690-h8fqijk5	177	1	Serum	serum	NN
cord-341690-h8fqijk5	177	2	-	-	HYPH
cord-341690-h8fqijk5	177	3	starved	starve	VBN
cord-341690-h8fqijk5	177	4	IPEC	IPEC	NNP
cord-341690-h8fqijk5	177	5	-	-	HYPH
cord-341690-h8fqijk5	177	6	J2	j2	NN
cord-341690-h8fqijk5	177	7	cells	cell	NNS
cord-341690-h8fqijk5	177	8	were	be	VBD
cord-341690-h8fqijk5	177	9	pretreated	pretreate	VBN
cord-341690-h8fqijk5	177	10	with	with	IN
cord-341690-h8fqijk5	177	11	different	different	JJ
cord-341690-h8fqijk5	177	12	high	high	JJ
cord-341690-h8fqijk5	177	13	concentrations	concentration	NNS
cord-341690-h8fqijk5	177	14	of	of	IN
cord-341690-h8fqijk5	177	15	EGF	EGF	NNP
cord-341690-h8fqijk5	177	16	at	at	IN
cord-341690-h8fqijk5	177	17	37	37	CD
cord-341690-h8fqijk5	177	18	°	°	NN
cord-341690-h8fqijk5	177	19	C	c	NN
cord-341690-h8fqijk5	177	20	for	for	IN
cord-341690-h8fqijk5	177	21	1	1	CD
cord-341690-h8fqijk5	177	22	h	h	NN
cord-341690-h8fqijk5	177	23	,	,	,
cord-341690-h8fqijk5	177	24	cells	cell	NNS
cord-341690-h8fqijk5	177	25	were	be	VBD
cord-341690-h8fqijk5	177	26	infected	infect	VBN
cord-341690-h8fqijk5	177	27	with	with	IN
cord-341690-h8fqijk5	177	28	TGEV	TGEV	NNP
cord-341690-h8fqijk5	177	29	for	for	IN
cord-341690-h8fqijk5	177	30	1	1	CD
cord-341690-h8fqijk5	177	31	h	h	NN
cord-341690-h8fqijk5	177	32	and	and	CC
cord-341690-h8fqijk5	177	33	entry	entry	NN
cord-341690-h8fqijk5	177	34	of	of	IN
cord-341690-h8fqijk5	177	35	TGEV	TGEV	NNP
cord-341690-h8fqijk5	177	36	was	be	VBD
cord-341690-h8fqijk5	177	37	evaluated	evaluate	VBN
cord-341690-h8fqijk5	177	38	by	by	IN
cord-341690-h8fqijk5	177	39	real	real	JJ
cord-341690-h8fqijk5	177	40	-	-	HYPH
cord-341690-h8fqijk5	177	41	time	time	NN
cord-341690-h8fqijk5	177	42	PCR	PCR	NNP
cord-341690-h8fqijk5	177	43	.	.	.
cord-341690-h8fqijk5	178	1	G.EGFR	G.EGFR	NNP
cord-341690-h8fqijk5	179	1	shRNAs	shRNAs	NNP
cord-341690-h8fqijk5	179	2	block	block	NN
cord-341690-h8fqijk5	179	3	TGEV	TGEV	NNP
cord-341690-h8fqijk5	179	4	entry	entry	NN
cord-341690-h8fqijk5	179	5	.	.	.
cord-341690-h8fqijk5	180	1	Cells	cell	NNS
cord-341690-h8fqijk5	180	2	were	be	VBD
cord-341690-h8fqijk5	180	3	transfected	transfecte	VBN
cord-341690-h8fqijk5	180	4	with	with	IN
cord-341690-h8fqijk5	180	5	lentiviral	lentiviral	JJ
cord-341690-h8fqijk5	180	6	particles	particle	NNS
cord-341690-h8fqijk5	180	7	expressing	express	VBG
cord-341690-h8fqijk5	180	8	EGFR	EGFR	NNP
cord-341690-h8fqijk5	180	9	shRNAs	shRNAs	NNP
cord-341690-h8fqijk5	180	10	.	.	.
cord-341690-h8fqijk5	181	1	48	48	CD
cord-341690-h8fqijk5	182	1	h	h	LS
cord-341690-h8fqijk5	182	2	post	post	NN
cord-341690-h8fqijk5	182	3	-	-	NN
cord-341690-h8fqijk5	182	4	infection	infection	NN
cord-341690-h8fqijk5	182	5	,	,	,
cord-341690-h8fqijk5	182	6	cells	cell	NNS
cord-341690-h8fqijk5	182	7	were	be	VBD
cord-341690-h8fqijk5	182	8	infected	infect	VBN
cord-341690-h8fqijk5	182	9	with	with	IN
cord-341690-h8fqijk5	182	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	182	11	for	for	IN
cord-341690-h8fqijk5	182	12	1	1	CD
cord-341690-h8fqijk5	182	13	h	h	NN
cord-341690-h8fqijk5	182	14	,	,	,
cord-341690-h8fqijk5	182	15	and	and	CC
cord-341690-h8fqijk5	182	16	entry	entry	NN
cord-341690-h8fqijk5	182	17	of	of	IN
cord-341690-h8fqijk5	182	18	TGEV	TGEV	NNP
cord-341690-h8fqijk5	182	19	was	be	VBD
cord-341690-h8fqijk5	182	20	evaluated	evaluate	VBN
cord-341690-h8fqijk5	182	21	by	by	IN
cord-341690-h8fqijk5	182	22	real	real	JJ
cord-341690-h8fqijk5	182	23	-	-	HYPH
cord-341690-h8fqijk5	182	24	time	time	NN
cord-341690-h8fqijk5	182	25	PCR	PCR	NNP
cord-341690-h8fqijk5	182	26	.	.	.
cord-341690-h8fqijk5	183	1	H.	H.	NNP
cord-341690-h8fqijk5	183	2	TGEV	TGEV	NNP
cord-341690-h8fqijk5	183	3	S1	S1	NNP
cord-341690-h8fqijk5	183	4	interacts	interact	VBZ
cord-341690-h8fqijk5	183	5	with	with	IN
cord-341690-h8fqijk5	183	6	EGFR	EGFR	NNP
cord-341690-h8fqijk5	183	7	.	.	.
cord-341690-h8fqijk5	184	1	Cells	cell	NNS
cord-341690-h8fqijk5	184	2	were	be	VBD
cord-341690-h8fqijk5	184	3	co	co	VBN
cord-341690-h8fqijk5	184	4	-	-	VBN
cord-341690-h8fqijk5	184	5	transfected	transfecte	VBN
cord-341690-h8fqijk5	184	6	with	with	IN
cord-341690-h8fqijk5	184	7	plasmids	plasmid	NNS
cord-341690-h8fqijk5	184	8	expressing	express	VBG
cord-341690-h8fqijk5	184	9	TGEV	TGEV	NNP
cord-341690-h8fqijk5	184	10	S1-HA	S1-HA	NNP
cord-341690-h8fqijk5	184	11	and	and	CC
cord-341690-h8fqijk5	184	12	EGFR	EGFR	NNP
cord-341690-h8fqijk5	184	13	.	.	.
cord-341690-h8fqijk5	185	1	Immunoprecipitation	immunoprecipitation	NN
cord-341690-h8fqijk5	185	2	and	and	CC
cord-341690-h8fqijk5	185	3	immunoblotting	immunoblotting	NN
cord-341690-h8fqijk5	185	4	were	be	VBD
cord-341690-h8fqijk5	185	5	performed	perform	VBN
cord-341690-h8fqijk5	185	6	to	to	TO
cord-341690-h8fqijk5	185	7	examine	examine	VB
cord-341690-h8fqijk5	185	8	interactions	interaction	NNS
cord-341690-h8fqijk5	185	9	between	between	IN
cord-341690-h8fqijk5	185	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	185	11	S1	S1	NNP
cord-341690-h8fqijk5	185	12	and	and	CC
cord-341690-h8fqijk5	185	13	EGFR	EGFR	NNP
cord-341690-h8fqijk5	185	14	.	.	.
cord-341690-h8fqijk5	186	1	Statistical	statistical	JJ
cord-341690-h8fqijk5	186	2	significance	significance	NN
cord-341690-h8fqijk5	186	3	was	be	VBD
cord-341690-h8fqijk5	186	4	assessed	assess	VBN
cord-341690-h8fqijk5	186	5	by	by	IN
cord-341690-h8fqijk5	186	6	Student	Student	NNP
cord-341690-h8fqijk5	186	7	's	's	POS
cord-341690-h8fqijk5	186	8	t	t	NN
cord-341690-h8fqijk5	186	9	-	-	HYPH
cord-341690-h8fqijk5	186	10	test	test	NN
cord-341690-h8fqijk5	186	11	.	.	.
cord-341690-h8fqijk5	187	1	Differences	difference	NNS
cord-341690-h8fqijk5	187	2	were	be	VBD
cord-341690-h8fqijk5	187	3	considered	consider	VBN
cord-341690-h8fqijk5	187	4	significant	significant	JJ
cord-341690-h8fqijk5	187	5	at	at	IN
cord-341690-h8fqijk5	187	6	(	(	-LRB-
cord-341690-h8fqijk5	187	7	*	*	NFP
cord-341690-h8fqijk5	187	8	)	)	-RRB-
cord-341690-h8fqijk5	187	9	0.01	0.01	CD
cord-341690-h8fqijk5	187	10	<	<	XX
cord-341690-h8fqijk5	187	11	p	p	XX
cord-341690-h8fqijk5	187	12	<	<	XX
cord-341690-h8fqijk5	187	13	0.05	0.05	CD
cord-341690-h8fqijk5	187	14	,	,	,
cord-341690-h8fqijk5	187	15	(	(	-LRB-
cord-341690-h8fqijk5	188	1	*	*	NFP
cord-341690-h8fqijk5	188	2	*	*	NFP
cord-341690-h8fqijk5	188	3	)	)	-RRB-
cord-341690-h8fqijk5	188	4	p	p	NN
cord-341690-h8fqijk5	188	5	<	<	XX
cord-341690-h8fqijk5	188	6	0.01	0.01	CD
cord-341690-h8fqijk5	188	7	.	.	.
cord-341690-h8fqijk5	189	1	All	all	DT
cord-341690-h8fqijk5	189	2	experiments	experiment	NNS
cord-341690-h8fqijk5	189	3	were	be	VBD
cord-341690-h8fqijk5	189	4	performed	perform	VBN
cord-341690-h8fqijk5	189	5	independently	independently	RB
cord-341690-h8fqijk5	189	6	three	three	CD
cord-341690-h8fqijk5	189	7	times	time	NNS
cord-341690-h8fqijk5	189	8	.	.	.
cord-341690-h8fqijk5	190	1	Scale	scale	NN
cord-341690-h8fqijk5	190	2	bar	bar	NN
cord-341690-h8fqijk5	190	3	=	=	SYM
cord-341690-h8fqijk5	190	4	20	20	CD
cord-341690-h8fqijk5	190	5	μm	μm	NN
cord-341690-h8fqijk5	190	6	.	.	.
cord-341690-h8fqijk5	191	1	TGEV	TGEV	NNP
cord-341690-h8fqijk5	191	2	at	at	IN
cord-341690-h8fqijk5	191	3	a	a	DT
cord-341690-h8fqijk5	191	4	multiplicity	multiplicity	NN
cord-341690-h8fqijk5	191	5	of	of	IN
cord-341690-h8fqijk5	191	6	infection	infection	NN
cord-341690-h8fqijk5	191	7	of	of	IN
cord-341690-h8fqijk5	191	8	2	2	CD
cord-341690-h8fqijk5	191	9	(	(	-LRB-
cord-341690-h8fqijk5	191	10	MOI	MOI	NNP
cord-341690-h8fqijk5	191	11	=	=	SYM
cord-341690-h8fqijk5	191	12	2	2	CD
cord-341690-h8fqijk5	191	13	)	)	-RRB-
cord-341690-h8fqijk5	191	14	.	.	.
cord-341690-h8fqijk5	192	1	www.impactjournals.com/oncotarget	www.impactjournals.com/oncotarget	NNP
cord-341690-h8fqijk5	193	1	We	-PRON-	PRP
cord-341690-h8fqijk5	193	2	have	have	VBP
cord-341690-h8fqijk5	193	3	concluded	conclude	VBN
cord-341690-h8fqijk5	193	4	that	that	IN
cord-341690-h8fqijk5	193	5	the	the	DT
cord-341690-h8fqijk5	193	6	PI3K	PI3K	NNP
cord-341690-h8fqijk5	193	7	/	/	SYM
cord-341690-h8fqijk5	193	8	Akt	Akt	NNP
cord-341690-h8fqijk5	193	9	pathway	pathway	NN
cord-341690-h8fqijk5	193	10	involve	involve	VBP
cord-341690-h8fqijk5	193	11	in	in	IN
cord-341690-h8fqijk5	193	12	TGEV	TGEV	NNP
cord-341690-h8fqijk5	193	13	infection	infection	NN
cord-341690-h8fqijk5	193	14	,	,	,
cord-341690-h8fqijk5	193	15	but	but	CC
cord-341690-h8fqijk5	193	16	the	the	DT
cord-341690-h8fqijk5	193	17	involvement	involvement	NN
cord-341690-h8fqijk5	193	18	of	of	IN
cord-341690-h8fqijk5	193	19	EGFR	EGFR	NNP
cord-341690-h8fqijk5	193	20	have	have	VBP
cord-341690-h8fqijk5	193	21	not	not	RB
cord-341690-h8fqijk5	193	22	been	be	VBN
cord-341690-h8fqijk5	193	23	demonstrated	demonstrate	VBN
cord-341690-h8fqijk5	193	24	.	.	.
cord-341690-h8fqijk5	194	1	To	to	TO
cord-341690-h8fqijk5	194	2	investigate	investigate	VB
cord-341690-h8fqijk5	194	3	the	the	DT
cord-341690-h8fqijk5	194	4	role	role	NN
cord-341690-h8fqijk5	194	5	of	of	IN
cord-341690-h8fqijk5	194	6	EGFR	EGFR	NNP
cord-341690-h8fqijk5	194	7	more	more	RBR
cord-341690-h8fqijk5	194	8	closely	closely	RB
cord-341690-h8fqijk5	194	9	,	,	,
cord-341690-h8fqijk5	194	10	we	-PRON-	PRP
cord-341690-h8fqijk5	194	11	stained	stain	VBD
cord-341690-h8fqijk5	194	12	cells	cell	NNS
cord-341690-h8fqijk5	194	13	with	with	IN
cord-341690-h8fqijk5	194	14	an	an	DT
cord-341690-h8fqijk5	194	15	anti	anti	JJ
cord-341690-h8fqijk5	194	16	-	-	JJ
cord-341690-h8fqijk5	194	17	p	p	JJ
cord-341690-h8fqijk5	194	18	-	-	HYPH
cord-341690-h8fqijk5	194	19	EGFR	egfr	NN
cord-341690-h8fqijk5	194	20	antibody	antibody	NN
cord-341690-h8fqijk5	194	21	after	after	IN
cord-341690-h8fqijk5	194	22	various	various	JJ
cord-341690-h8fqijk5	194	23	treatments	treatment	NNS
cord-341690-h8fqijk5	194	24	and	and	CC
cord-341690-h8fqijk5	194	25	then	then	RB
cord-341690-h8fqijk5	194	26	observed	observe	VBD
cord-341690-h8fqijk5	194	27	them	-PRON-	PRP
cord-341690-h8fqijk5	194	28	using	use	VBG
cord-341690-h8fqijk5	194	29	fluorescence	fluorescence	NN
cord-341690-h8fqijk5	194	30	microscopy	microscopy	NN
cord-341690-h8fqijk5	194	31	.	.	.
cord-341690-h8fqijk5	195	1	At	at	IN
cord-341690-h8fqijk5	195	2	10	10	CD
cord-341690-h8fqijk5	195	3	mpi	mpi	NN
cord-341690-h8fqijk5	195	4	,	,	,
cord-341690-h8fqijk5	195	5	both	both	CC
cord-341690-h8fqijk5	195	6	TGEV	TGEV	NNP
cord-341690-h8fqijk5	195	7	and	and	CC
cord-341690-h8fqijk5	195	8	EGF	EGF	NNP
cord-341690-h8fqijk5	195	9	increased	increase	VBD
cord-341690-h8fqijk5	195	10	the	the	DT
cord-341690-h8fqijk5	195	11	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	195	12	level	level	NN
cord-341690-h8fqijk5	195	13	of	of	IN
cord-341690-h8fqijk5	195	14	EGFR	EGFR	NNP
cord-341690-h8fqijk5	195	15	,	,	,
cord-341690-h8fqijk5	195	16	but	but	CC
cord-341690-h8fqijk5	195	17	EGFR	EGFR	NNP
cord-341690-h8fqijk5	195	18	specific	specific	JJ
cord-341690-h8fqijk5	195	19	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	195	20	AG1478	ag1478	NN
cord-341690-h8fqijk5	195	21	significantly	significantly	RB
cord-341690-h8fqijk5	195	22	impaired	impair	VBD
cord-341690-h8fqijk5	195	23	EGFR	EGFR	NNP
cord-341690-h8fqijk5	195	24	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	195	25	(	(	-LRB-
cord-341690-h8fqijk5	195	26	Figure	figure	NN
cord-341690-h8fqijk5	195	27	5A	5a	NN
cord-341690-h8fqijk5	195	28	)	)	-RRB-
cord-341690-h8fqijk5	195	29	.	.	.
cord-341690-h8fqijk5	196	1	Western	western	JJ
cord-341690-h8fqijk5	196	2	blotting	blotting	NN
cord-341690-h8fqijk5	196	3	results	result	NNS
cord-341690-h8fqijk5	196	4	confirmed	confirm	VBD
cord-341690-h8fqijk5	196	5	that	that	IN
cord-341690-h8fqijk5	196	6	the	the	DT
cord-341690-h8fqijk5	196	7	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	196	8	level	level	NN
cord-341690-h8fqijk5	196	9	of	of	IN
cord-341690-h8fqijk5	196	10	EGFR	EGFR	NNP
cord-341690-h8fqijk5	196	11	increased	increase	VBD
cord-341690-h8fqijk5	196	12	from	from	IN
cord-341690-h8fqijk5	196	13	5	5	CD
cord-341690-h8fqijk5	196	14	mpi	mpi	NNP
cord-341690-h8fqijk5	196	15	to	to	IN
cord-341690-h8fqijk5	196	16	30	30	CD
cord-341690-h8fqijk5	196	17	mpi	mpi	NN
cord-341690-h8fqijk5	196	18	and	and	CC
cord-341690-h8fqijk5	196	19	reaching	reach	VBG
cord-341690-h8fqijk5	196	20	a	a	DT
cord-341690-h8fqijk5	196	21	peak	peak	NN
cord-341690-h8fqijk5	196	22	at	at	IN
cord-341690-h8fqijk5	196	23	10	10	CD
cord-341690-h8fqijk5	196	24	mpi	mpi	NNP
cord-341690-h8fqijk5	196	25	(	(	-LRB-
cord-341690-h8fqijk5	196	26	Figure	figure	NN
cord-341690-h8fqijk5	196	27	5B	5b	NN
cord-341690-h8fqijk5	196	28	)	)	-RRB-
cord-341690-h8fqijk5	196	29	.	.	.
cord-341690-h8fqijk5	197	1	To	to	TO
cord-341690-h8fqijk5	197	2	study	study	VB
cord-341690-h8fqijk5	197	3	the	the	DT
cord-341690-h8fqijk5	197	4	relationship	relationship	NN
cord-341690-h8fqijk5	197	5	between	between	IN
cord-341690-h8fqijk5	197	6	EGFR	EGFR	NNP
cord-341690-h8fqijk5	197	7	and	and	CC
cord-341690-h8fqijk5	197	8	downstream	downstream	JJ
cord-341690-h8fqijk5	197	9	signaling	signal	VBG
cord-341690-h8fqijk5	197	10	pathways	pathway	NNS
cord-341690-h8fqijk5	197	11	,	,	,
cord-341690-h8fqijk5	197	12	we	-PRON-	PRP
cord-341690-h8fqijk5	197	13	conducted	conduct	VBD
cord-341690-h8fqijk5	197	14	experiments	experiment	NNS
cord-341690-h8fqijk5	197	15	using	use	VBG
cord-341690-h8fqijk5	197	16	different	different	JJ
cord-341690-h8fqijk5	197	17	inhibitors	inhibitor	NNS
cord-341690-h8fqijk5	197	18	and	and	CC
cord-341690-h8fqijk5	197	19	EGFR	EGFR	NNP
cord-341690-h8fqijk5	197	20	shRNAs	shRNAs	NNP
cord-341690-h8fqijk5	197	21	.	.	.
cord-341690-h8fqijk5	198	1	As	as	IN
cord-341690-h8fqijk5	198	2	expected	expect	VBN
cord-341690-h8fqijk5	198	3	,	,	,
cord-341690-h8fqijk5	198	4	EGFR	EGFR	NNP
cord-341690-h8fqijk5	198	5	-	-	HYPH
cord-341690-h8fqijk5	198	6	targeting	target	VBG
cord-341690-h8fqijk5	198	7	shRNAs	shRNAs	NNP
cord-341690-h8fqijk5	198	8	significantly	significantly	RB
cord-341690-h8fqijk5	198	9	inhibited	inhibit	VBD
cord-341690-h8fqijk5	198	10	EGFR	EGFR	NNP
cord-341690-h8fqijk5	198	11	expression	expression	NN
cord-341690-h8fqijk5	198	12	(	(	-LRB-
cord-341690-h8fqijk5	198	13	Figure	figure	NN
cord-341690-h8fqijk5	198	14	5C	5c	CD
cord-341690-h8fqijk5	198	15	)	)	-RRB-
cord-341690-h8fqijk5	198	16	.	.	.
cord-341690-h8fqijk5	199	1	The	the	DT
cord-341690-h8fqijk5	199	2	activation	activation	NN
cord-341690-h8fqijk5	199	3	of	of	IN
cord-341690-h8fqijk5	199	4	Akt	Akt	NNP
cord-341690-h8fqijk5	199	5	,	,	,
cord-341690-h8fqijk5	199	6	LIMK	LIMK	NNP
cord-341690-h8fqijk5	199	7	,	,	,
cord-341690-h8fqijk5	199	8	and	and	CC
cord-341690-h8fqijk5	199	9	cofilin	cofilin	NN
cord-341690-h8fqijk5	199	10	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	199	11	were	be	VBD
cord-341690-h8fqijk5	199	12	inhibited	inhibit	VBN
cord-341690-h8fqijk5	199	13	by	by	IN
cord-341690-h8fqijk5	199	14	EGFR	EGFR	NNP
cord-341690-h8fqijk5	199	15	shRNAs	shRNAs	NNP
cord-341690-h8fqijk5	199	16	(	(	-LRB-
cord-341690-h8fqijk5	199	17	Figure	Figure	NNP
cord-341690-h8fqijk5	199	18	5D	5d	CD
cord-341690-h8fqijk5	199	19	)	)	-RRB-
cord-341690-h8fqijk5	199	20	,	,	,
cord-341690-h8fqijk5	199	21	as	as	RB
cord-341690-h8fqijk5	199	22	well	well	RB
cord-341690-h8fqijk5	199	23	as	as	IN
cord-341690-h8fqijk5	199	24	with	with	IN
cord-341690-h8fqijk5	199	25	RTK	RTK	NNP
cord-341690-h8fqijk5	199	26	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	199	27	Gen	Gen	NNP
cord-341690-h8fqijk5	199	28	,	,	,
cord-341690-h8fqijk5	199	29	and	and	CC
cord-341690-h8fqijk5	199	30	EGFR	EGFR	NNP
cord-341690-h8fqijk5	199	31	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	200	1	AG1478	AG1478	NNP
cord-341690-h8fqijk5	200	2	(	(	-LRB-
cord-341690-h8fqijk5	200	3	Figure	figure	NN
cord-341690-h8fqijk5	200	4	5E	5e	NN
cord-341690-h8fqijk5	200	5	)	)	-RRB-
cord-341690-h8fqijk5	200	6	.	.	.
cord-341690-h8fqijk5	201	1	The	the	DT
cord-341690-h8fqijk5	201	2	activity	activity	NN
cord-341690-h8fqijk5	201	3	of	of	IN
cord-341690-h8fqijk5	201	4	ERK1/2	ERK1/2	NNP
cord-341690-h8fqijk5	201	5	was	be	VBD
cord-341690-h8fqijk5	201	6	also	also	RB
cord-341690-h8fqijk5	201	7	inhibited	inhibit	VBN
cord-341690-h8fqijk5	201	8	by	by	IN
cord-341690-h8fqijk5	201	9	EGFR	EGFR	NNP
cord-341690-h8fqijk5	201	10	shRNAs	shRNAs	NNP
cord-341690-h8fqijk5	201	11	,	,	,
cord-341690-h8fqijk5	201	12	Gen	Gen	NNP
cord-341690-h8fqijk5	201	13	,	,	,
cord-341690-h8fqijk5	201	14	and	and	CC
cord-341690-h8fqijk5	201	15	AG1478	ag1478	NN
cord-341690-h8fqijk5	201	16	.	.	.
cord-341690-h8fqijk5	202	1	TGEV	TGEV	NNP
cord-341690-h8fqijk5	202	2	infection	infection	NN
cord-341690-h8fqijk5	202	3	caused	cause	VBD
cord-341690-h8fqijk5	202	4	the	the	DT
cord-341690-h8fqijk5	202	5	dissolution	dissolution	NN
cord-341690-h8fqijk5	202	6	of	of	IN
cord-341690-h8fqijk5	202	7	stress	stress	NN
cord-341690-h8fqijk5	202	8	fibers	fiber	NNS
cord-341690-h8fqijk5	202	9	and	and	CC
cord-341690-h8fqijk5	202	10	stimulated	stimulate	VBD
cord-341690-h8fqijk5	202	11	the	the	DT
cord-341690-h8fqijk5	202	12	formation	formation	NN
cord-341690-h8fqijk5	202	13	of	of	IN
cord-341690-h8fqijk5	202	14	membrane	membrane	NN
cord-341690-h8fqijk5	202	15	protrusions	protrusion	NNS
cord-341690-h8fqijk5	202	16	,	,	,
cord-341690-h8fqijk5	202	17	but	but	CC
cord-341690-h8fqijk5	202	18	these	these	DT
cord-341690-h8fqijk5	202	19	phenomena	phenomenon	NNS
cord-341690-h8fqijk5	202	20	were	be	VBD
cord-341690-h8fqijk5	202	21	blocked	block	VBN
cord-341690-h8fqijk5	202	22	by	by	IN
cord-341690-h8fqijk5	202	23	AG1478	ag1478	NN
cord-341690-h8fqijk5	202	24	treatment	treatment	NN
cord-341690-h8fqijk5	202	25	(	(	-LRB-
cord-341690-h8fqijk5	202	26	Figure	figure	NN
cord-341690-h8fqijk5	202	27	5F	5f	NN
cord-341690-h8fqijk5	202	28	)	)	-RRB-
cord-341690-h8fqijk5	202	29	.	.	.
cord-341690-h8fqijk5	203	1	Taken	take	VBN
cord-341690-h8fqijk5	203	2	together	together	RB
cord-341690-h8fqijk5	203	3	,	,	,
cord-341690-h8fqijk5	203	4	these	these	DT
cord-341690-h8fqijk5	203	5	results	result	NNS
cord-341690-h8fqijk5	203	6	indicate	indicate	VBP
cord-341690-h8fqijk5	203	7	that	that	IN
cord-341690-h8fqijk5	203	8	EGFR	EGFR	NNP
cord-341690-h8fqijk5	203	9	is	be	VBZ
cord-341690-h8fqijk5	203	10	involved	involve	VBN
cord-341690-h8fqijk5	203	11	in	in	IN
cord-341690-h8fqijk5	203	12	the	the	DT
cord-341690-h8fqijk5	203	13	entry	entry	NN
cord-341690-h8fqijk5	203	14	of	of	IN
cord-341690-h8fqijk5	203	15	TGEV	TGEV	NNP
cord-341690-h8fqijk5	203	16	and	and	CC
cord-341690-h8fqijk5	203	17	the	the	DT
cord-341690-h8fqijk5	203	18	activation	activation	NN
cord-341690-h8fqijk5	203	19	of	of	IN
cord-341690-h8fqijk5	203	20	downstream	downstream	JJ
cord-341690-h8fqijk5	203	21	pathways	pathway	NNS
cord-341690-h8fqijk5	203	22	early	early	RB
cord-341690-h8fqijk5	203	23	in	in	IN
cord-341690-h8fqijk5	203	24	the	the	DT
cord-341690-h8fqijk5	203	25	infection	infection	NN
cord-341690-h8fqijk5	203	26	process	process	NN
cord-341690-h8fqijk5	203	27	.	.	.
cord-341690-h8fqijk5	204	1	Using	use	VBG
cord-341690-h8fqijk5	204	2	fluorescence	fluorescence	NN
cord-341690-h8fqijk5	204	3	microscopy	microscopy	NNS
cord-341690-h8fqijk5	204	4	,	,	,
cord-341690-h8fqijk5	204	5	we	-PRON-	PRP
cord-341690-h8fqijk5	204	6	found	find	VBD
cord-341690-h8fqijk5	204	7	that	that	IN
cord-341690-h8fqijk5	204	8	the	the	DT
cord-341690-h8fqijk5	204	9	spike	spike	NN
cord-341690-h8fqijk5	204	10	protein	protein	NN
cord-341690-h8fqijk5	204	11	of	of	IN
cord-341690-h8fqijk5	204	12	TGEV	TGEV	NNP
cord-341690-h8fqijk5	204	13	co	co	NN
cord-341690-h8fqijk5	204	14	-	-	VBN
cord-341690-h8fqijk5	204	15	localized	localize	VBN
cord-341690-h8fqijk5	204	16	with	with	IN
cord-341690-h8fqijk5	204	17	p	p	NN
cord-341690-h8fqijk5	204	18	-	-	HYPH
cord-341690-h8fqijk5	204	19	EGFR	EGFR	NNP
cord-341690-h8fqijk5	204	20	(	(	-LRB-
cord-341690-h8fqijk5	204	21	Figure	figure	NN
cord-341690-h8fqijk5	204	22	6A	6a	CD
cord-341690-h8fqijk5	204	23	)	)	-RRB-
cord-341690-h8fqijk5	204	24	.	.	.
cord-341690-h8fqijk5	205	1	The	the	DT
cord-341690-h8fqijk5	205	2	RTK	RTK	NNP
cord-341690-h8fqijk5	205	3	specific	specific	JJ
cord-341690-h8fqijk5	205	4	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	205	5	genistein	genistein	NN
cord-341690-h8fqijk5	205	6	(	(	-LRB-
cord-341690-h8fqijk5	205	7	Gen	Gen	NNP
cord-341690-h8fqijk5	205	8	)	)	-RRB-
cord-341690-h8fqijk5	205	9	had	have	VBD
cord-341690-h8fqijk5	205	10	no	no	DT
cord-341690-h8fqijk5	205	11	inhibition	inhibition	NN
cord-341690-h8fqijk5	205	12	effect	effect	NN
cord-341690-h8fqijk5	205	13	on	on	IN
cord-341690-h8fqijk5	205	14	the	the	DT
cord-341690-h8fqijk5	205	15	adhesion	adhesion	NN
cord-341690-h8fqijk5	205	16	of	of	IN
cord-341690-h8fqijk5	205	17	TGEV	TGEV	NNP
cord-341690-h8fqijk5	205	18	,	,	,
cord-341690-h8fqijk5	205	19	but	but	CC
cord-341690-h8fqijk5	205	20	inhibited	inhibit	VBN
cord-341690-h8fqijk5	205	21	TGEV	TGEV	NNP
cord-341690-h8fqijk5	205	22	entry	entry	NN
cord-341690-h8fqijk5	205	23	in	in	IN
cord-341690-h8fqijk5	205	24	a	a	DT
cord-341690-h8fqijk5	205	25	dose	dose	NN
cord-341690-h8fqijk5	205	26	dependent	dependent	JJ
cord-341690-h8fqijk5	205	27	manner	manner	NN
cord-341690-h8fqijk5	205	28	(	(	-LRB-
cord-341690-h8fqijk5	205	29	Figure	figure	NN
cord-341690-h8fqijk5	205	30	 	 	_SP
cord-341690-h8fqijk5	205	31	6B	6b	CD
cord-341690-h8fqijk5	205	32	)	)	-RRB-
cord-341690-h8fqijk5	205	33	.	.	.
cord-341690-h8fqijk5	206	1	Although	although	IN
cord-341690-h8fqijk5	206	2	EGFR	EGFR	NNP
cord-341690-h8fqijk5	206	3	specific	specific	JJ
cord-341690-h8fqijk5	206	4	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	206	5	AG1478	ag1478	NN
cord-341690-h8fqijk5	206	6	had	have	VBD
cord-341690-h8fqijk5	206	7	no	no	DT
cord-341690-h8fqijk5	206	8	inhibition	inhibition	NN
cord-341690-h8fqijk5	206	9	effect	effect	NN
cord-341690-h8fqijk5	206	10	on	on	IN
cord-341690-h8fqijk5	206	11	the	the	DT
cord-341690-h8fqijk5	206	12	adhesion	adhesion	NN
cord-341690-h8fqijk5	206	13	of	of	IN
cord-341690-h8fqijk5	206	14	TGEV	TGEV	NNP
cord-341690-h8fqijk5	206	15	(	(	-LRB-
cord-341690-h8fqijk5	206	16	Figure	figure	NN
cord-341690-h8fqijk5	206	17	6C	6c	NN
cord-341690-h8fqijk5	206	18	)	)	-RRB-
cord-341690-h8fqijk5	206	19	,	,	,
cord-341690-h8fqijk5	206	20	when	when	WRB
cord-341690-h8fqijk5	206	21	IPEC	IPEC	NNP
cord-341690-h8fqijk5	206	22	-	-	HYPH
cord-341690-h8fqijk5	206	23	J2	j2	NN
cord-341690-h8fqijk5	206	24	cells	cell	NNS
cord-341690-h8fqijk5	206	25	were	be	VBD
cord-341690-h8fqijk5	206	26	pretreated	pretreate	VBN
cord-341690-h8fqijk5	206	27	with	with	IN
cord-341690-h8fqijk5	206	28	AG1478	ag1478	NN
cord-341690-h8fqijk5	206	29	for	for	IN
cord-341690-h8fqijk5	206	30	1h	1h	CD
cord-341690-h8fqijk5	206	31	at	at	IN
cord-341690-h8fqijk5	206	32	37	37	CD
cord-341690-h8fqijk5	206	33	°	°	NN
cord-341690-h8fqijk5	206	34	C	c	NN
cord-341690-h8fqijk5	206	35	,	,	,
cord-341690-h8fqijk5	206	36	TGEV	TGEV	NNP
cord-341690-h8fqijk5	206	37	entry	entry	NN
cord-341690-h8fqijk5	206	38	was	be	VBD
cord-341690-h8fqijk5	206	39	significantly	significantly	RB
cord-341690-h8fqijk5	206	40	decreased	decrease	VBN
cord-341690-h8fqijk5	206	41	(	(	-LRB-
cord-341690-h8fqijk5	206	42	Figure	Figure	NNP
cord-341690-h8fqijk5	206	43	6D	6d	NN
cord-341690-h8fqijk5	206	44	)	)	-RRB-
cord-341690-h8fqijk5	206	45	.	.	.
cord-341690-h8fqijk5	207	1	AG1478	ag1478	NN
cord-341690-h8fqijk5	207	2	appeared	appear	VBD
cord-341690-h8fqijk5	207	3	to	to	TO
cord-341690-h8fqijk5	207	4	act	act	VB
cord-341690-h8fqijk5	207	5	only	only	RB
cord-341690-h8fqijk5	207	6	at	at	IN
cord-341690-h8fqijk5	207	7	early	early	JJ
cord-341690-h8fqijk5	207	8	stage	stage	NN
cord-341690-h8fqijk5	207	9	of	of	IN
cord-341690-h8fqijk5	207	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	207	11	entry	entry	NN
cord-341690-h8fqijk5	207	12	,	,	,
cord-341690-h8fqijk5	207	13	shortly	shortly	RB
cord-341690-h8fqijk5	207	14	after	after	IN
cord-341690-h8fqijk5	207	15	the	the	DT
cord-341690-h8fqijk5	207	16	virus	virus	NN
cord-341690-h8fqijk5	207	17	bound	bind	VBN
cord-341690-h8fqijk5	207	18	to	to	IN
cord-341690-h8fqijk5	207	19	the	the	DT
cord-341690-h8fqijk5	207	20	cell	cell	NN
cord-341690-h8fqijk5	207	21	(	(	-LRB-
cord-341690-h8fqijk5	207	22	Figure	Figure	NNP
cord-341690-h8fqijk5	207	23	6D	6d	NN
cord-341690-h8fqijk5	207	24	)	)	-RRB-
cord-341690-h8fqijk5	207	25	.	.	.
cord-341690-h8fqijk5	208	1	When	when	WRB
cord-341690-h8fqijk5	208	2	serum	serum	NN
cord-341690-h8fqijk5	208	3	-	-	HYPH
cord-341690-h8fqijk5	208	4	starved	starve	VBN
cord-341690-h8fqijk5	208	5	cells	cell	NNS
cord-341690-h8fqijk5	208	6	were	be	VBD
cord-341690-h8fqijk5	208	7	pretreated	pretreate	VBN
cord-341690-h8fqijk5	208	8	with	with	IN
cord-341690-h8fqijk5	208	9	low	low	JJ
cord-341690-h8fqijk5	208	10	concentration	concentration	NN
cord-341690-h8fqijk5	208	11	of	of	IN
cord-341690-h8fqijk5	208	12	EGF	EGF	NNP
cord-341690-h8fqijk5	208	13	at	at	IN
cord-341690-h8fqijk5	208	14	37	37	CD
cord-341690-h8fqijk5	208	15	°	°	NN
cord-341690-h8fqijk5	208	16	C	c	NN
cord-341690-h8fqijk5	208	17	for	for	IN
cord-341690-h8fqijk5	208	18	1h	1h	CD
cord-341690-h8fqijk5	208	19	,	,	,
cord-341690-h8fqijk5	208	20	EGFR	EGFR	NNP
cord-341690-h8fqijk5	208	21	was	be	VBD
cord-341690-h8fqijk5	208	22	activated	activate	VBN
cord-341690-h8fqijk5	208	23	and	and	CC
cord-341690-h8fqijk5	208	24	TGEV	TGEV	NNP
cord-341690-h8fqijk5	208	25	entry	entry	NN
cord-341690-h8fqijk5	208	26	was	be	VBD
cord-341690-h8fqijk5	208	27	increased	increase	VBN
cord-341690-h8fqijk5	208	28	significantly	significantly	RB
cord-341690-h8fqijk5	208	29	(	(	-LRB-
cord-341690-h8fqijk5	208	30	Figure	Figure	NNP
cord-341690-h8fqijk5	208	31	6E	6E	NNP
cord-341690-h8fqijk5	208	32	)	)	-RRB-
cord-341690-h8fqijk5	208	33	.	.	.
cord-341690-h8fqijk5	209	1	When	when	WRB
cord-341690-h8fqijk5	209	2	serum	serum	NN
cord-341690-h8fqijk5	209	3	-	-	HYPH
cord-341690-h8fqijk5	209	4	starved	starve	VBN
cord-341690-h8fqijk5	209	5	cells	cell	NNS
cord-341690-h8fqijk5	209	6	were	be	VBD
cord-341690-h8fqijk5	209	7	pretreated	pretreate	VBN
cord-341690-h8fqijk5	209	8	with	with	IN
cord-341690-h8fqijk5	209	9	high	high	JJ
cord-341690-h8fqijk5	209	10	concentration	concentration	NN
cord-341690-h8fqijk5	209	11	of	of	IN
cord-341690-h8fqijk5	209	12	EGF	EGF	NNP
cord-341690-h8fqijk5	209	13	at	at	IN
cord-341690-h8fqijk5	209	14	37	37	CD
cord-341690-h8fqijk5	209	15	°	°	NN
cord-341690-h8fqijk5	209	16	C	c	NN
cord-341690-h8fqijk5	209	17	for	for	IN
cord-341690-h8fqijk5	209	18	1h	1h	CD
cord-341690-h8fqijk5	209	19	,	,	,
cord-341690-h8fqijk5	209	20	most	most	JJS
cord-341690-h8fqijk5	209	21	of	of	IN
cord-341690-h8fqijk5	209	22	EGFR	EGFR	NNP
cord-341690-h8fqijk5	209	23	internalized	internalize	VBN
cord-341690-h8fqijk5	209	24	into	into	IN
cord-341690-h8fqijk5	209	25	the	the	DT
cord-341690-h8fqijk5	209	26	cytoplasm	cytoplasm	NN
cord-341690-h8fqijk5	209	27	and	and	CC
cord-341690-h8fqijk5	209	28	TGEV	TGEV	NNP
cord-341690-h8fqijk5	209	29	entry	entry	NN
cord-341690-h8fqijk5	209	30	was	be	VBD
cord-341690-h8fqijk5	209	31	decreased	decrease	VBN
cord-341690-h8fqijk5	209	32	significantly	significantly	RB
cord-341690-h8fqijk5	209	33	(	(	-LRB-
cord-341690-h8fqijk5	209	34	Figure	figure	NN
cord-341690-h8fqijk5	209	35	6F	6f	NN
cord-341690-h8fqijk5	209	36	)	)	-RRB-
cord-341690-h8fqijk5	209	37	.	.	.
cord-341690-h8fqijk5	210	1	EGFR	EGFR	NNP
cord-341690-h8fqijk5	210	2	targeting	target	VBG
cord-341690-h8fqijk5	210	3	shRNAs	shRNAs	NNP
cord-341690-h8fqijk5	210	4	significantly	significantly	RB
cord-341690-h8fqijk5	210	5	decreased	decrease	VBD
cord-341690-h8fqijk5	210	6	TGEV	TGEV	NNP
cord-341690-h8fqijk5	210	7	entry	entry	NN
cord-341690-h8fqijk5	210	8	(	(	-LRB-
cord-341690-h8fqijk5	210	9	Figure	figure	NN
cord-341690-h8fqijk5	210	10	 	 	_SP
cord-341690-h8fqijk5	210	11	6	6	CD
cord-341690-h8fqijk5	210	12	G	g	NN
cord-341690-h8fqijk5	210	13	)	)	-RRB-
cord-341690-h8fqijk5	210	14	.	.	.
cord-341690-h8fqijk5	211	1	The	the	DT
cord-341690-h8fqijk5	211	2	interaction	interaction	NN
cord-341690-h8fqijk5	211	3	between	between	IN
cord-341690-h8fqijk5	211	4	TGEV	TGEV	NNP
cord-341690-h8fqijk5	211	5	S1	S1	NNP
cord-341690-h8fqijk5	211	6	and	and	CC
cord-341690-h8fqijk5	211	7	EGFR	EGFR	NNP
cord-341690-h8fqijk5	211	8	were	be	VBD
cord-341690-h8fqijk5	211	9	confirmed	confirm	VBN
cord-341690-h8fqijk5	211	10	in	in	IN
cord-341690-h8fqijk5	211	11	HEK293	HEK293	NNP
cord-341690-h8fqijk5	211	12	T	T	NNP
cord-341690-h8fqijk5	211	13	cells	cell	NNS
cord-341690-h8fqijk5	211	14	that	that	WDT
cord-341690-h8fqijk5	211	15	were	be	VBD
cord-341690-h8fqijk5	211	16	co	co	VBN
cord-341690-h8fqijk5	211	17	-	-	VBN
cord-341690-h8fqijk5	211	18	transfected	transfecte	VBN
cord-341690-h8fqijk5	211	19	with	with	IN
cord-341690-h8fqijk5	211	20	plasmids	plasmid	NNS
cord-341690-h8fqijk5	211	21	expressing	express	VBG
cord-341690-h8fqijk5	211	22	TGEV	TGEV	NNP
cord-341690-h8fqijk5	211	23	S1-HA	S1-HA	NNP
cord-341690-h8fqijk5	211	24	and	and	CC
cord-341690-h8fqijk5	211	25	EGFR	EGFR	NNP
cord-341690-h8fqijk5	211	26	(	(	-LRB-
cord-341690-h8fqijk5	211	27	Figure	Figure	NNP
cord-341690-h8fqijk5	211	28	 	 	_SP
cord-341690-h8fqijk5	211	29	6H	6H	NNP
cord-341690-h8fqijk5	211	30	)	)	-RRB-
cord-341690-h8fqijk5	211	31	,	,	,
cord-341690-h8fqijk5	211	32	providing	provide	VBG
cord-341690-h8fqijk5	211	33	further	further	JJ
cord-341690-h8fqijk5	211	34	support	support	NN
cord-341690-h8fqijk5	211	35	that	that	IN
cord-341690-h8fqijk5	211	36	TGEV	TGEV	NNP
cord-341690-h8fqijk5	211	37	S1	S1	NNP
cord-341690-h8fqijk5	211	38	directly	directly	RB
cord-341690-h8fqijk5	211	39	combined	combine	VBN
cord-341690-h8fqijk5	211	40	with	with	IN
cord-341690-h8fqijk5	211	41	EGFR	EGFR	NNP
cord-341690-h8fqijk5	211	42	.	.	.
cord-341690-h8fqijk5	212	1	Most	Most	JJS
cord-341690-h8fqijk5	212	2	of	of	IN
cord-341690-h8fqijk5	212	3	EGFR	EGFR	NNP
cord-341690-h8fqijk5	212	4	occured	occur	VBD
cord-341690-h8fqijk5	212	5	in	in	IN
cord-341690-h8fqijk5	212	6	the	the	DT
cord-341690-h8fqijk5	212	7	cell	cell	NN
cord-341690-h8fqijk5	212	8	membrane	membrane	NN
cord-341690-h8fqijk5	212	9	in	in	IN
cord-341690-h8fqijk5	212	10	normal	normal	JJ
cord-341690-h8fqijk5	212	11	cells	cell	NNS
cord-341690-h8fqijk5	212	12	,	,	,
cord-341690-h8fqijk5	212	13	part	part	NN
cord-341690-h8fqijk5	212	14	of	of	IN
cord-341690-h8fqijk5	212	15	EGFR	EGFR	NNP
cord-341690-h8fqijk5	212	16	internalized	internalize	VBN
cord-341690-h8fqijk5	212	17	into	into	IN
cord-341690-h8fqijk5	212	18	the	the	DT
cord-341690-h8fqijk5	212	19	cytoplasm	cytoplasm	NN
cord-341690-h8fqijk5	212	20	upon	upon	IN
cord-341690-h8fqijk5	212	21	low	low	JJ
cord-341690-h8fqijk5	212	22	concentration	concentration	NN
cord-341690-h8fqijk5	212	23	EGF	EGF	NNP
cord-341690-h8fqijk5	212	24	(	(	-LRB-
cord-341690-h8fqijk5	212	25	100ng	100ng	NNP
cord-341690-h8fqijk5	212	26	/	/	SYM
cord-341690-h8fqijk5	212	27	ml	ml	NN
cord-341690-h8fqijk5	212	28	)	)	-RRB-
cord-341690-h8fqijk5	212	29	stimulation	stimulation	NN
cord-341690-h8fqijk5	212	30	,	,	,
cord-341690-h8fqijk5	212	31	most	most	JJS
cord-341690-h8fqijk5	212	32	of	of	IN
cord-341690-h8fqijk5	212	33	EGFR	EGFR	NNP
cord-341690-h8fqijk5	212	34	internalized	internalize	VBN
cord-341690-h8fqijk5	212	35	into	into	IN
cord-341690-h8fqijk5	212	36	the	the	DT
cord-341690-h8fqijk5	212	37	cytoplasm	cytoplasm	NN
cord-341690-h8fqijk5	212	38	upon	upon	IN
cord-341690-h8fqijk5	212	39	high	high	JJ
cord-341690-h8fqijk5	212	40	concentration	concentration	NN
cord-341690-h8fqijk5	212	41	EGF(10ug	egf(10ug	NN
cord-341690-h8fqijk5	212	42	/	/	SYM
cord-341690-h8fqijk5	212	43	ml	ml	NN
cord-341690-h8fqijk5	212	44	)	)	-RRB-
cord-341690-h8fqijk5	212	45	stimulation	stimulation	NN
cord-341690-h8fqijk5	212	46	,	,	,
cord-341690-h8fqijk5	212	47	both	both	CC
cord-341690-h8fqijk5	212	48	TGEV	TGEV	NNP
cord-341690-h8fqijk5	212	49	particles	particle	NNS
cord-341690-h8fqijk5	212	50	and	and	CC
cord-341690-h8fqijk5	212	51	EGFR	EGFR	NNP
cord-341690-h8fqijk5	212	52	internalized	internalize	VBN
cord-341690-h8fqijk5	212	53	into	into	IN
cord-341690-h8fqijk5	212	54	the	the	DT
cord-341690-h8fqijk5	212	55	cytoplasm	cytoplasm	NN
cord-341690-h8fqijk5	212	56	upon	upon	IN
cord-341690-h8fqijk5	212	57	TGEV	TGEV	NNP
cord-341690-h8fqijk5	212	58	infection	infection	NN
cord-341690-h8fqijk5	212	59	(	(	-LRB-
cord-341690-h8fqijk5	212	60	Figure	figure	NN
cord-341690-h8fqijk5	212	61	S3	S3	NNP
cord-341690-h8fqijk5	212	62	)	)	-RRB-
cord-341690-h8fqijk5	212	63	.	.	.
cord-341690-h8fqijk5	213	1	Taken	take	VBN
cord-341690-h8fqijk5	213	2	together	together	RB
cord-341690-h8fqijk5	213	3	,	,	,
cord-341690-h8fqijk5	213	4	these	these	DT
cord-341690-h8fqijk5	213	5	results	result	NNS
cord-341690-h8fqijk5	213	6	indicate	indicate	VBP
cord-341690-h8fqijk5	213	7	that	that	IN
cord-341690-h8fqijk5	213	8	EGFR	EGFR	NNP
cord-341690-h8fqijk5	213	9	acts	act	NNS
cord-341690-h8fqijk5	213	10	as	as	IN
cord-341690-h8fqijk5	213	11	a	a	DT
cord-341690-h8fqijk5	213	12	membrane	membrane	NN
cord-341690-h8fqijk5	213	13	promoter	promoter	NN
cord-341690-h8fqijk5	213	14	for	for	IN
cord-341690-h8fqijk5	213	15	TGEV	TGEV	NNP
cord-341690-h8fqijk5	213	16	entry	entry	NN
cord-341690-h8fqijk5	213	17	.	.	.
cord-341690-h8fqijk5	214	1	When	when	WRB
cord-341690-h8fqijk5	214	2	EGFR	EGFR	NNP
cord-341690-h8fqijk5	214	3	in	in	IN
cord-341690-h8fqijk5	214	4	the	the	DT
cord-341690-h8fqijk5	214	5	lipid	lipid	NN
cord-341690-h8fqijk5	214	6	rafts	raft	NNS
cord-341690-h8fqijk5	214	7	is	be	VBZ
cord-341690-h8fqijk5	214	8	stimulated	stimulate	VBN
cord-341690-h8fqijk5	214	9	,	,	,
cord-341690-h8fqijk5	214	10	the	the	DT
cord-341690-h8fqijk5	214	11	endocytosis	endocytosis	NN
cord-341690-h8fqijk5	214	12	of	of	IN
cord-341690-h8fqijk5	214	13	membrane	membrane	NN
cord-341690-h8fqijk5	214	14	microdomains	microdomain	NNS
cord-341690-h8fqijk5	214	15	via	via	IN
cord-341690-h8fqijk5	214	16	clathrindependent	clathrindependent	NN
cord-341690-h8fqijk5	214	17	and	and	CC
cord-341690-h8fqijk5	214	18	clathrin	clathrin	NN
cord-341690-h8fqijk5	214	19	-	-	HYPH
cord-341690-h8fqijk5	214	20	independent	independent	JJ
cord-341690-h8fqijk5	214	21	mechanisms	mechanism	NNS
cord-341690-h8fqijk5	214	22	occurs	occur	VBZ
cord-341690-h8fqijk5	214	23	[	[	-LRB-
cord-341690-h8fqijk5	214	24	24	24	CD
cord-341690-h8fqijk5	214	25	,	,	,
cord-341690-h8fqijk5	214	26	25	25	CD
cord-341690-h8fqijk5	214	27	]	]	-RRB-
cord-341690-h8fqijk5	214	28	.	.	.
cord-341690-h8fqijk5	215	1	Lipid	lipid	NN
cord-341690-h8fqijk5	215	2	rafts	raft	NNS
cord-341690-h8fqijk5	215	3	are	be	VBP
cord-341690-h8fqijk5	215	4	mainly	mainly	RB
cord-341690-h8fqijk5	215	5	composed	compose	VBN
cord-341690-h8fqijk5	215	6	of	of	IN
cord-341690-h8fqijk5	215	7	sphingolipid	sphingolipid	NN
cord-341690-h8fqijk5	215	8	and	and	CC
cord-341690-h8fqijk5	215	9	cholesterol	cholesterol	NN
cord-341690-h8fqijk5	215	10	[	[	-LRB-
cord-341690-h8fqijk5	215	11	26	26	CD
cord-341690-h8fqijk5	215	12	]	]	-RRB-
cord-341690-h8fqijk5	215	13	.	.	.
cord-341690-h8fqijk5	216	1	Ganglioside	Ganglioside	NNP
cord-341690-h8fqijk5	216	2	GM1	GM1	NNP
cord-341690-h8fqijk5	216	3	serves	serve	VBZ
cord-341690-h8fqijk5	216	4	as	as	IN
cord-341690-h8fqijk5	216	5	lipid	lipid	NN
cord-341690-h8fqijk5	216	6	rafts	raft	NNS
cord-341690-h8fqijk5	216	7	marker	marker	NN
cord-341690-h8fqijk5	216	8	and	and	CC
cord-341690-h8fqijk5	216	9	can	can	MD
cord-341690-h8fqijk5	216	10	be	be	VB
cord-341690-h8fqijk5	216	11	labeled	label	VBN
cord-341690-h8fqijk5	216	12	with	with	IN
cord-341690-h8fqijk5	216	13	fluorescein	fluorescein	NN
cord-341690-h8fqijk5	216	14	isothiocyanate	isothiocyanate	NN
cord-341690-h8fqijk5	216	15	(	(	-LRB-
cord-341690-h8fqijk5	216	16	FITC)-conjugated	fitc)-conjugated	CD
cord-341690-h8fqijk5	216	17	cholera	cholera	NN
cord-341690-h8fqijk5	216	18	toxin	toxin	NN
cord-341690-h8fqijk5	216	19	beta	beta	NN
cord-341690-h8fqijk5	216	20	subunit	subunit	NN
cord-341690-h8fqijk5	216	21	(	(	-LRB-
cord-341690-h8fqijk5	216	22	CtxB	CtxB	NNP
cord-341690-h8fqijk5	216	23	)	)	-RRB-
cord-341690-h8fqijk5	216	24	[	[	-LRB-
cord-341690-h8fqijk5	216	25	18	18	CD
cord-341690-h8fqijk5	216	26	,	,	,
cord-341690-h8fqijk5	216	27	19	19	CD
cord-341690-h8fqijk5	216	28	]	]	-RRB-
cord-341690-h8fqijk5	216	29	.	.	.
cord-341690-h8fqijk5	217	1	Using	use	VBG
cord-341690-h8fqijk5	217	2	this	this	DT
cord-341690-h8fqijk5	217	3	reagent	reagent	NN
cord-341690-h8fqijk5	217	4	,	,	,
cord-341690-h8fqijk5	217	5	we	-PRON-	PRP
cord-341690-h8fqijk5	217	6	found	find	VBD
cord-341690-h8fqijk5	217	7	that	that	IN
cord-341690-h8fqijk5	217	8	lipid	lipid	NN
cord-341690-h8fqijk5	217	9	rafts	raft	NNS
cord-341690-h8fqijk5	217	10	distributed	distribute	VBN
cord-341690-h8fqijk5	217	11	evenly	evenly	RB
cord-341690-h8fqijk5	217	12	in	in	IN
cord-341690-h8fqijk5	217	13	the	the	DT
cord-341690-h8fqijk5	217	14	cell	cell	NN
cord-341690-h8fqijk5	217	15	membrane	membrane	NN
cord-341690-h8fqijk5	217	16	of	of	IN
cord-341690-h8fqijk5	217	17	untreated	untreated	JJ
cord-341690-h8fqijk5	217	18	cells	cell	NNS
cord-341690-h8fqijk5	217	19	.	.	.
cord-341690-h8fqijk5	218	1	In	in	IN
cord-341690-h8fqijk5	218	2	contrast	contrast	NN
cord-341690-h8fqijk5	218	3	,	,	,
cord-341690-h8fqijk5	218	4	the	the	DT
cord-341690-h8fqijk5	218	5	lipid	lipid	NN
cord-341690-h8fqijk5	218	6	rafts	raft	NNS
cord-341690-h8fqijk5	218	7	clustered	cluster	VBN
cord-341690-h8fqijk5	218	8	in	in	IN
cord-341690-h8fqijk5	218	9	EGF	EGF	NNP
cord-341690-h8fqijk5	218	10	treated	treat	VBD
cord-341690-h8fqijk5	218	11	or	or	CC
cord-341690-h8fqijk5	218	12	TGEV	TGEV	NNP
cord-341690-h8fqijk5	218	13	infected	infect	VBN
cord-341690-h8fqijk5	218	14	cells	cell	NNS
cord-341690-h8fqijk5	218	15	(	(	-LRB-
cord-341690-h8fqijk5	218	16	Figure	figure	NN
cord-341690-h8fqijk5	218	17	7A	7a	NN
cord-341690-h8fqijk5	218	18	)	)	-RRB-
cord-341690-h8fqijk5	218	19	.	.	.
cord-341690-h8fqijk5	219	1	These	these	DT
cord-341690-h8fqijk5	219	2	results	result	NNS
cord-341690-h8fqijk5	219	3	show	show	VBP
cord-341690-h8fqijk5	219	4	that	that	IN
cord-341690-h8fqijk5	219	5	TGEV	TGEV	NNP
cord-341690-h8fqijk5	219	6	infection	infection	NN
cord-341690-h8fqijk5	219	7	causes	cause	VBZ
cord-341690-h8fqijk5	219	8	lipid	lipid	NN
cord-341690-h8fqijk5	219	9	rafts	raft	NNS
cord-341690-h8fqijk5	219	10	function	function	VBP
cord-341690-h8fqijk5	219	11	as	as	IN
cord-341690-h8fqijk5	219	12	a	a	DT
cord-341690-h8fqijk5	219	13	platform	platform	NN
cord-341690-h8fqijk5	219	14	to	to	TO
cord-341690-h8fqijk5	219	15	concentrate	concentrate	VB
cord-341690-h8fqijk5	219	16	APN	APN	NNP
cord-341690-h8fqijk5	219	17	and	and	CC
cord-341690-h8fqijk5	219	18	EGFR	EGFR	NNP
cord-341690-h8fqijk5	219	19	.	.	.
cord-341690-h8fqijk5	220	1	To	to	TO
cord-341690-h8fqijk5	220	2	analyze	analyze	VB
cord-341690-h8fqijk5	220	3	whether	whether	IN
cord-341690-h8fqijk5	220	4	TGEV	TGEV	NNP
cord-341690-h8fqijk5	220	5	or	or	CC
cord-341690-h8fqijk5	220	6	EGFR	EGFR	NNP
cord-341690-h8fqijk5	220	7	is	be	VBZ
cord-341690-h8fqijk5	220	8	present	present	JJ
cord-341690-h8fqijk5	220	9	in	in	IN
cord-341690-h8fqijk5	220	10	lipid	lipid	NN
cord-341690-h8fqijk5	220	11	rafts	raft	NNS
cord-341690-h8fqijk5	220	12	upon	upon	IN
cord-341690-h8fqijk5	220	13	TGEV	TGEV	NNP
cord-341690-h8fqijk5	220	14	infection	infection	NN
cord-341690-h8fqijk5	220	15	,	,	,
cord-341690-h8fqijk5	220	16	co	co	NN
cord-341690-h8fqijk5	220	17	-	-	NN
cord-341690-h8fqijk5	220	18	localization	localization	NN
cord-341690-h8fqijk5	220	19	experiments	experiment	NNS
cord-341690-h8fqijk5	220	20	were	be	VBD
cord-341690-h8fqijk5	220	21	performed	perform	VBN
cord-341690-h8fqijk5	220	22	.	.	.
cord-341690-h8fqijk5	221	1	Lipid	lipid	NN
cord-341690-h8fqijk5	221	2	rafts	raft	NNS
cord-341690-h8fqijk5	221	3	were	be	VBD
cord-341690-h8fqijk5	221	4	labeled	label	VBN
cord-341690-h8fqijk5	221	5	with	with	IN
cord-341690-h8fqijk5	221	6	FITC	FITC	NNP
cord-341690-h8fqijk5	221	7	-	-	HYPH
cord-341690-h8fqijk5	221	8	conjugated	conjugate	VBN
cord-341690-h8fqijk5	221	9	CtxB	CtxB	NNP
cord-341690-h8fqijk5	221	10	,	,	,
cord-341690-h8fqijk5	221	11	TGEV	TGEV	NNP
cord-341690-h8fqijk5	221	12	was	be	VBD
cord-341690-h8fqijk5	221	13	stained	stain	VBN
cord-341690-h8fqijk5	221	14	with	with	IN
cord-341690-h8fqijk5	221	15	mouse	mouse	NN
cord-341690-h8fqijk5	221	16	anti	anti	JJ
cord-341690-h8fqijk5	221	17	-	-	JJ
cord-341690-h8fqijk5	221	18	TGEV	tgev	JJ
cord-341690-h8fqijk5	221	19	mAb	mAb	NNS
cord-341690-h8fqijk5	221	20	,	,	,
cord-341690-h8fqijk5	221	21	and	and	CC
cord-341690-h8fqijk5	221	22	EGFR	EGFR	NNP
cord-341690-h8fqijk5	221	23	was	be	VBD
cord-341690-h8fqijk5	221	24	stained	stain	VBN
cord-341690-h8fqijk5	221	25	with	with	IN
cord-341690-h8fqijk5	221	26	rabbit	rabbit	NN
cord-341690-h8fqijk5	221	27	anti	anti	JJ
cord-341690-h8fqijk5	221	28	-	-	JJ
cord-341690-h8fqijk5	221	29	EGFR	egfr	JJ
cord-341690-h8fqijk5	221	30	pAb	pab	NN
cord-341690-h8fqijk5	221	31	.	.	.
cord-341690-h8fqijk5	222	1	Both	both	DT
cord-341690-h8fqijk5	222	2	TGEV	TGEV	NNP
cord-341690-h8fqijk5	222	3	and	and	CC
cord-341690-h8fqijk5	222	4	EGFR	EGFR	NNP
cord-341690-h8fqijk5	222	5	co	co	NN
cord-341690-h8fqijk5	222	6	-	-	VBD
cord-341690-h8fqijk5	222	7	localized	localize	VBN
cord-341690-h8fqijk5	222	8	with	with	IN
cord-341690-h8fqijk5	222	9	GM1	GM1	NNP
cord-341690-h8fqijk5	222	10	at	at	IN
cord-341690-h8fqijk5	222	11	the	the	DT
cord-341690-h8fqijk5	222	12	cell	cell	NN
cord-341690-h8fqijk5	222	13	surface	surface	NN
cord-341690-h8fqijk5	222	14	(	(	-LRB-
cord-341690-h8fqijk5	222	15	Figure	figure	NN
cord-341690-h8fqijk5	222	16	7B	7b	NN
cord-341690-h8fqijk5	222	17	)	)	-RRB-
cord-341690-h8fqijk5	222	18	.	.	.
cord-341690-h8fqijk5	223	1	Therefore	therefore	RB
cord-341690-h8fqijk5	223	2	,	,	,
cord-341690-h8fqijk5	223	3	we	-PRON-	PRP
cord-341690-h8fqijk5	223	4	conclude	conclude	VBP
cord-341690-h8fqijk5	223	5	that	that	IN
cord-341690-h8fqijk5	223	6	EGFR	EGFR	NNP
cord-341690-h8fqijk5	223	7	and	and	CC
cord-341690-h8fqijk5	223	8	the	the	DT
cord-341690-h8fqijk5	223	9	attaching	attach	VBG
cord-341690-h8fqijk5	223	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	223	11	particles	particle	NNS
cord-341690-h8fqijk5	223	12	are	be	VBP
cord-341690-h8fqijk5	223	13	located	locate	VBN
cord-341690-h8fqijk5	223	14	together	together	RB
cord-341690-h8fqijk5	223	15	in	in	IN
cord-341690-h8fqijk5	223	16	the	the	DT
cord-341690-h8fqijk5	223	17	lipid	lipid	NN
cord-341690-h8fqijk5	223	18	rafts	raft	NNS
cord-341690-h8fqijk5	223	19	during	during	IN
cord-341690-h8fqijk5	223	20	infection	infection	NN
cord-341690-h8fqijk5	223	21	.	.	.
cord-341690-h8fqijk5	224	1	For	for	IN
cord-341690-h8fqijk5	224	2	studying	study	VBG
cord-341690-h8fqijk5	224	3	the	the	DT
cord-341690-h8fqijk5	224	4	role	role	NN
cord-341690-h8fqijk5	224	5	of	of	IN
cord-341690-h8fqijk5	224	6	lipid	lipid	NN
cord-341690-h8fqijk5	224	7	rafts	raft	NNS
cord-341690-h8fqijk5	224	8	in	in	IN
cord-341690-h8fqijk5	224	9	the	the	DT
cord-341690-h8fqijk5	224	10	entry	entry	NN
cord-341690-h8fqijk5	224	11	process	process	NN
cord-341690-h8fqijk5	224	12	of	of	IN
cord-341690-h8fqijk5	224	13	TGEV	TGEV	NNP
cord-341690-h8fqijk5	224	14	,	,	,
cord-341690-h8fqijk5	224	15	both	both	DT
cord-341690-h8fqijk5	224	16	methyl	methyl	NN
cord-341690-h8fqijk5	224	17	-	-	HYPH
cord-341690-h8fqijk5	224	18	β	β	NN
cord-341690-h8fqijk5	224	19	-	-	HYPH
cord-341690-h8fqijk5	224	20	cyclodextrin	cyclodextrin	NNP
cord-341690-h8fqijk5	224	21	(	(	-LRB-
cord-341690-h8fqijk5	224	22	MβCD	MβCD	NNP
cord-341690-h8fqijk5	224	23	)	)	-RRB-
cord-341690-h8fqijk5	225	1	and	and	CC
cord-341690-h8fqijk5	225	2	nystatin	nystatin	NNS
cord-341690-h8fqijk5	225	3	were	be	VBD
cord-341690-h8fqijk5	225	4	used	use	VBN
cord-341690-h8fqijk5	225	5	to	to	TO
cord-341690-h8fqijk5	225	6	remove	remove	VB
cord-341690-h8fqijk5	225	7	the	the	DT
cord-341690-h8fqijk5	225	8	cholesterol	cholesterol	NN
cord-341690-h8fqijk5	225	9	from	from	IN
cord-341690-h8fqijk5	225	10	the	the	DT
cord-341690-h8fqijk5	225	11	cell	cell	NN
cord-341690-h8fqijk5	225	12	membrane	membrane	NN
cord-341690-h8fqijk5	225	13	.	.	.
cord-341690-h8fqijk5	226	1	The	the	DT
cord-341690-h8fqijk5	226	2	effect	effect	NN
cord-341690-h8fqijk5	226	3	of	of	IN
cord-341690-h8fqijk5	226	4	these	these	DT
cord-341690-h8fqijk5	226	5	inhibitors	inhibitor	NNS
cord-341690-h8fqijk5	226	6	on	on	IN
cord-341690-h8fqijk5	226	7	cell	cell	NN
cord-341690-h8fqijk5	226	8	viability	viability	NN
cord-341690-h8fqijk5	226	9	were	be	VBD
cord-341690-h8fqijk5	226	10	shown	show	VBN
cord-341690-h8fqijk5	226	11	in	in	IN
cord-341690-h8fqijk5	226	12	S1	S1	NNP
cord-341690-h8fqijk5	226	13	Fig	Fig	NNP
cord-341690-h8fqijk5	226	14	.	.	.
cord-341690-h8fqijk5	227	1	Cells	cell	NNS
cord-341690-h8fqijk5	227	2	were	be	VBD
cord-341690-h8fqijk5	227	3	pretreated	pretreate	VBN
cord-341690-h8fqijk5	227	4	with	with	IN
cord-341690-h8fqijk5	227	5	different	different	JJ
cord-341690-h8fqijk5	227	6	concentrations	concentration	NNS
cord-341690-h8fqijk5	227	7	of	of	IN
cord-341690-h8fqijk5	227	8	MβCD	mβcd	NN
cord-341690-h8fqijk5	227	9	or	or	CC
cord-341690-h8fqijk5	227	10	nystatin	nystatin	NNS
cord-341690-h8fqijk5	227	11	at	at	IN
cord-341690-h8fqijk5	227	12	37	37	CD
cord-341690-h8fqijk5	227	13	°	°	NN
cord-341690-h8fqijk5	227	14	C	c	NN
cord-341690-h8fqijk5	227	15	for	for	IN
cord-341690-h8fqijk5	227	16	1h	1h	CD
cord-341690-h8fqijk5	227	17	prior	prior	RB
cord-341690-h8fqijk5	227	18	to	to	IN
cord-341690-h8fqijk5	227	19	infection	infection	NN
cord-341690-h8fqijk5	227	20	,	,	,
cord-341690-h8fqijk5	227	21	both	both	CC
cord-341690-h8fqijk5	227	22	TGEV	TGEV	NNS
cord-341690-h8fqijk5	227	23	binding	bind	VBG
cord-341690-h8fqijk5	227	24	and	and	CC
cord-341690-h8fqijk5	227	25	entry	entry	NN
cord-341690-h8fqijk5	227	26	levels	level	NNS
cord-341690-h8fqijk5	227	27	were	be	VBD
cord-341690-h8fqijk5	227	28	inhibited	inhibit	VBN
cord-341690-h8fqijk5	227	29	in	in	IN
cord-341690-h8fqijk5	227	30	a	a	DT
cord-341690-h8fqijk5	227	31	dose	dose	NN
cord-341690-h8fqijk5	227	32	dependent	dependent	JJ
cord-341690-h8fqijk5	227	33	manner	manner	NN
cord-341690-h8fqijk5	227	34	compared	compare	VBN
cord-341690-h8fqijk5	227	35	with	with	IN
cord-341690-h8fqijk5	227	36	mock	mock	JJ
cord-341690-h8fqijk5	227	37	control	control	NN
cord-341690-h8fqijk5	227	38	cells	cell	NNS
cord-341690-h8fqijk5	227	39	(	(	-LRB-
cord-341690-h8fqijk5	227	40	Figure	Figure	NNP
cord-341690-h8fqijk5	227	41	7C	7C	NNP
cord-341690-h8fqijk5	227	42	,	,	,
cord-341690-h8fqijk5	227	43	7D	7D	NNP
cord-341690-h8fqijk5	227	44	)	)	-RRB-
cord-341690-h8fqijk5	227	45	.	.	.
cord-341690-h8fqijk5	228	1	These	these	DT
cord-341690-h8fqijk5	228	2	results	result	NNS
cord-341690-h8fqijk5	228	3	suggest	suggest	VBP
cord-341690-h8fqijk5	228	4	that	that	IN
cord-341690-h8fqijk5	228	5	lipid	lipid	NN
cord-341690-h8fqijk5	228	6	rafts	raft	NNS
cord-341690-h8fqijk5	228	7	play	play	VBP
cord-341690-h8fqijk5	228	8	an	an	DT
cord-341690-h8fqijk5	228	9	important	important	JJ
cord-341690-h8fqijk5	228	10	role	role	NN
cord-341690-h8fqijk5	228	11	in	in	IN
cord-341690-h8fqijk5	228	12	TGEV	TGEV	NNP
cord-341690-h8fqijk5	228	13	binding	binding	NN
cord-341690-h8fqijk5	228	14	and	and	CC
cord-341690-h8fqijk5	228	15	entry	entry	NN
cord-341690-h8fqijk5	228	16	.	.	.
cord-341690-h8fqijk5	229	1	During	during	IN
cord-341690-h8fqijk5	229	2	the	the	DT
cord-341690-h8fqijk5	229	3	early	early	JJ
cord-341690-h8fqijk5	229	4	phase	phase	NN
cord-341690-h8fqijk5	229	5	of	of	IN
cord-341690-h8fqijk5	229	6	TGEV	TGEV	NNP
cord-341690-h8fqijk5	229	7	infection	infection	NN
cord-341690-h8fqijk5	229	8	,	,	,
cord-341690-h8fqijk5	229	9	the	the	DT
cord-341690-h8fqijk5	229	10	destruction	destruction	NN
cord-341690-h8fqijk5	229	11	of	of	IN
cord-341690-h8fqijk5	229	12	lipid	lipid	NN
cord-341690-h8fqijk5	229	13	rafts	raft	NNS
cord-341690-h8fqijk5	229	14	inhibited	inhibit	VBD
cord-341690-h8fqijk5	229	15	the	the	DT
cord-341690-h8fqijk5	229	16	activation	activation	NN
cord-341690-h8fqijk5	229	17	of	of	IN
cord-341690-h8fqijk5	229	18	EGFR	EGFR	NNP
cord-341690-h8fqijk5	229	19	,	,	,
cord-341690-h8fqijk5	229	20	Akt	Akt	NNP
cord-341690-h8fqijk5	229	21	,	,	,
cord-341690-h8fqijk5	229	22	and	and	CC
cord-341690-h8fqijk5	229	23	LIMK	LIMK	NNP
cord-341690-h8fqijk5	229	24	,	,	,
cord-341690-h8fqijk5	229	25	and	and	CC
cord-341690-h8fqijk5	229	26	also	also	RB
cord-341690-h8fqijk5	229	27	inhibited	inhibit	VBD
cord-341690-h8fqijk5	229	28	the	the	DT
cord-341690-h8fqijk5	229	29	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	229	30	of	of	IN
cord-341690-h8fqijk5	229	31	cofilin	cofilin	NN
cord-341690-h8fqijk5	229	32	(	(	-LRB-
cord-341690-h8fqijk5	229	33	Figure	Figure	NNP
cord-341690-h8fqijk5	229	34	7E	7E	NNP
cord-341690-h8fqijk5	229	35	)	)	-RRB-
cord-341690-h8fqijk5	229	36	.	.	.
cord-341690-h8fqijk5	230	1	These	these	DT
cord-341690-h8fqijk5	230	2	results	result	NNS
cord-341690-h8fqijk5	230	3	indicate	indicate	VBP
cord-341690-h8fqijk5	230	4	that	that	IN
cord-341690-h8fqijk5	230	5	lipid	lipid	NN
cord-341690-h8fqijk5	230	6	rafts	raft	NNS
cord-341690-h8fqijk5	230	7	function	function	VBP
cord-341690-h8fqijk5	230	8	as	as	IN
cord-341690-h8fqijk5	230	9	a	a	DT
cord-341690-h8fqijk5	230	10	platform	platform	NN
cord-341690-h8fqijk5	230	11	to	to	TO
cord-341690-h8fqijk5	230	12	induce	induce	VB
cord-341690-h8fqijk5	230	13	the	the	DT
cord-341690-h8fqijk5	230	14	activation	activation	NN
cord-341690-h8fqijk5	230	15	of	of	IN
cord-341690-h8fqijk5	230	16	EGFR	EGFR	NNP
cord-341690-h8fqijk5	230	17	 	 	_SP
cord-341690-h8fqijk5	230	18	The	the	DT
cord-341690-h8fqijk5	230	19	role	role	NN
cord-341690-h8fqijk5	230	20	of	of	IN
cord-341690-h8fqijk5	230	21	actin	actin	NN
cord-341690-h8fqijk5	230	22	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	230	23	in	in	IN
cord-341690-h8fqijk5	230	24	TGEV	TGEV	NNP
cord-341690-h8fqijk5	230	25	entry	entry	NN
cord-341690-h8fqijk5	230	26	process	process	NN
cord-341690-h8fqijk5	230	27	is	be	VBZ
cord-341690-h8fqijk5	230	28	unclear	unclear	JJ
cord-341690-h8fqijk5	230	29	.	.	.
cord-341690-h8fqijk5	231	1	We	-PRON-	PRP
cord-341690-h8fqijk5	231	2	had	have	VBD
cord-341690-h8fqijk5	231	3	shown	show	VBN
cord-341690-h8fqijk5	231	4	that	that	IN
cord-341690-h8fqijk5	231	5	TGEV	TGEV	NNP
cord-341690-h8fqijk5	231	6	induced	induce	VBN
cord-341690-h8fqijk5	231	7	F	F	NNP
cord-341690-h8fqijk5	231	8	-	-	HYPH
cord-341690-h8fqijk5	231	9	actin	actin	JJ
cord-341690-h8fqijk5	231	10	rearrangement	rearrangement	NN
cord-341690-h8fqijk5	231	11	and	and	CC
cord-341690-h8fqijk5	231	12	caused	cause	VBD
cord-341690-h8fqijk5	231	13	membrane	membrane	NN
cord-341690-h8fqijk5	231	14	ruffles	ruffle	NNS
cord-341690-h8fqijk5	231	15	.	.	.
cord-341690-h8fqijk5	232	1	TGEV	TGEV	NNP
cord-341690-h8fqijk5	232	2	entry	entry	NN
cord-341690-h8fqijk5	232	3	required	require	VBD
cord-341690-h8fqijk5	232	4	F	F	NNP
cord-341690-h8fqijk5	232	5	-	-	HYPH
cord-341690-h8fqijk5	232	6	actin	actin	NNP
cord-341690-h8fqijk5	232	7	gathered	gather	VBD
cord-341690-h8fqijk5	232	8	at	at	IN
cord-341690-h8fqijk5	232	9	the	the	DT
cord-341690-h8fqijk5	232	10	cell	cell	NN
cord-341690-h8fqijk5	232	11	membrane	membrane	NN
cord-341690-h8fqijk5	232	12	.	.	.
cord-341690-h8fqijk5	233	1	We	-PRON-	PRP
cord-341690-h8fqijk5	233	2	identified	identify	VBD
cord-341690-h8fqijk5	233	3	cofilin	cofilin	NN
cord-341690-h8fqijk5	233	4	as	as	IN
cord-341690-h8fqijk5	233	5	a	a	DT
cord-341690-h8fqijk5	233	6	critical	critical	JJ
cord-341690-h8fqijk5	233	7	factor	factor	NN
cord-341690-h8fqijk5	233	8	for	for	IN
cord-341690-h8fqijk5	233	9	regulating	regulate	VBG
cord-341690-h8fqijk5	233	10	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	233	11	dynamics	dynamic	NNS
cord-341690-h8fqijk5	233	12	and	and	CC
cord-341690-h8fqijk5	233	13	TGEV	TGEV	NNP
cord-341690-h8fqijk5	233	14	infection	infection	NN
cord-341690-h8fqijk5	233	15	.	.	.
cord-341690-h8fqijk5	234	1	Our	-PRON-	PRP$
cord-341690-h8fqijk5	234	2	results	result	NNS
cord-341690-h8fqijk5	234	3	also	also	RB
cord-341690-h8fqijk5	234	4	indicate	indicate	VBP
cord-341690-h8fqijk5	234	5	that	that	IN
cord-341690-h8fqijk5	234	6	TGEV	TGEV	NNP
cord-341690-h8fqijk5	234	7	binding	bind	VBG
cord-341690-h8fqijk5	234	8	induces	induce	VBZ
cord-341690-h8fqijk5	234	9	the	the	DT
cord-341690-h8fqijk5	234	10	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	234	11	of	of	IN
cord-341690-h8fqijk5	234	12	cofilin	cofilin	NN
cord-341690-h8fqijk5	234	13	through	through	IN
cord-341690-h8fqijk5	234	14	the	the	DT
cord-341690-h8fqijk5	234	15	EGFR	EGFR	NNP
cord-341690-h8fqijk5	234	16	-	-	HYPH
cord-341690-h8fqijk5	234	17	PI3K	PI3K	NNP
cord-341690-h8fqijk5	234	18	-	-	HYPH
cord-341690-h8fqijk5	234	19	Rac1/	Rac1/	NNP
cord-341690-h8fqijk5	234	20	Cdc42-PAK	Cdc42-PAK	NNP
cord-341690-h8fqijk5	234	21	-	-	HYPH
cord-341690-h8fqijk5	234	22	LIMK	LIMK	NNP
cord-341690-h8fqijk5	234	23	signaling	signal	VBG
cord-341690-h8fqijk5	234	24	pathways	pathway	NNS
cord-341690-h8fqijk5	234	25	,	,	,
cord-341690-h8fqijk5	234	26	resulting	result	VBG
cord-341690-h8fqijk5	234	27	in	in	IN
cord-341690-h8fqijk5	234	28	actin	actin	NN
cord-341690-h8fqijk5	234	29	polymerization	polymerization	NN
cord-341690-h8fqijk5	234	30	around	around	IN
cord-341690-h8fqijk5	234	31	the	the	DT
cord-341690-h8fqijk5	234	32	cell	cell	NN
cord-341690-h8fqijk5	234	33	membrane	membrane	NN
cord-341690-h8fqijk5	234	34	and	and	CC
cord-341690-h8fqijk5	234	35	foming	fome	VBG
cord-341690-h8fqijk5	234	36	multiple	multiple	JJ
cord-341690-h8fqijk5	234	37	poutrusions	poutrusion	NNS
cord-341690-h8fqijk5	234	38	.	.	.
cord-341690-h8fqijk5	235	1	The	the	DT
cord-341690-h8fqijk5	235	2	highly	highly	RB
cord-341690-h8fqijk5	235	3	dynamic	dynamic	JJ
cord-341690-h8fqijk5	235	4	nature	nature	NN
cord-341690-h8fqijk5	235	5	of	of	IN
cord-341690-h8fqijk5	235	6	actin	actin	NN
cord-341690-h8fqijk5	235	7	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	235	8	affects	affect	VBZ
cord-341690-h8fqijk5	235	9	every	every	DT
cord-341690-h8fqijk5	235	10	stage	stage	NN
cord-341690-h8fqijk5	235	11	of	of	IN
cord-341690-h8fqijk5	235	12	the	the	DT
cord-341690-h8fqijk5	235	13	viral	viral	JJ
cord-341690-h8fqijk5	235	14	life	life	NN
cord-341690-h8fqijk5	235	15	cycle	cycle	NN
cord-341690-h8fqijk5	235	16	,	,	,
cord-341690-h8fqijk5	235	17	from	from	IN
cord-341690-h8fqijk5	235	18	entry	entry	NN
cord-341690-h8fqijk5	235	19	through	through	IN
cord-341690-h8fqijk5	235	20	assembly	assembly	NN
cord-341690-h8fqijk5	235	21	to	to	TO
cord-341690-h8fqijk5	235	22	release	release	VB
cord-341690-h8fqijk5	235	23	.	.	.
cord-341690-h8fqijk5	236	1	Virion	virion	NN
cord-341690-h8fqijk5	236	2	attachment	attachment	NN
cord-341690-h8fqijk5	236	3	to	to	IN
cord-341690-h8fqijk5	236	4	cells	cell	NNS
cord-341690-h8fqijk5	236	5	can	can	MD
cord-341690-h8fqijk5	236	6	stimulate	stimulate	VB
cord-341690-h8fqijk5	236	7	the	the	DT
cord-341690-h8fqijk5	236	8	extension	extension	NN
cord-341690-h8fqijk5	236	9	of	of	IN
cord-341690-h8fqijk5	236	10	cell	cell	NN
cord-341690-h8fqijk5	236	11	surface	surface	NN
cord-341690-h8fqijk5	236	12	protrusions	protrusion	NNS
cord-341690-h8fqijk5	236	13	[	[	-LRB-
cord-341690-h8fqijk5	236	14	4	4	CD
cord-341690-h8fqijk5	236	15	]	]	-RRB-
cord-341690-h8fqijk5	236	16	.	.	.
cord-341690-h8fqijk5	237	1	Human	Human	NNP
cord-341690-h8fqijk5	237	2	Immunodeficiency	Immunodeficiency	NNP
cord-341690-h8fqijk5	237	3	Virus	Virus	NNP
cord-341690-h8fqijk5	237	4	(	(	-LRB-
cord-341690-h8fqijk5	237	5	HIV	HIV	NNP
cord-341690-h8fqijk5	237	6	)	)	-RRB-
cord-341690-h8fqijk5	237	7	and	and	CC
cord-341690-h8fqijk5	237	8	Herpes	Herpes	NNP
cord-341690-h8fqijk5	237	9	simplex	simplex	NN
cord-341690-h8fqijk5	237	10	virus	virus	NN
cord-341690-h8fqijk5	238	1	(	(	-LRB-
cord-341690-h8fqijk5	238	2	HSV	HSV	NNP
cord-341690-h8fqijk5	238	3	)	)	-RRB-
cord-341690-h8fqijk5	238	4	virions	virion	NNS
cord-341690-h8fqijk5	238	5	cause	cause	VBP
cord-341690-h8fqijk5	238	6	cell	cell	NN
cord-341690-h8fqijk5	238	7	surface	surface	NN
cord-341690-h8fqijk5	238	8	extensions	extension	NNS
cord-341690-h8fqijk5	238	9	and	and	CC
cord-341690-h8fqijk5	238	10	viral	viral	JJ
cord-341690-h8fqijk5	238	11	-	-	HYPH
cord-341690-h8fqijk5	238	12	entry	entry	NN
cord-341690-h8fqijk5	238	13	receptor	receptor	NN
cord-341690-h8fqijk5	238	14	clustering	clustering	NN
cord-341690-h8fqijk5	238	15	[	[	-LRB-
cord-341690-h8fqijk5	238	16	27	27	CD
cord-341690-h8fqijk5	238	17	,	,	,
cord-341690-h8fqijk5	238	18	28	28	CD
cord-341690-h8fqijk5	238	19	]	]	-RRB-
cord-341690-h8fqijk5	238	20	.	.	.
cord-341690-h8fqijk5	239	1	The	the	DT
cord-341690-h8fqijk5	239	2	entry	entry	NN
cord-341690-h8fqijk5	239	3	of	of	IN
cord-341690-h8fqijk5	239	4	vesicular	vesicular	JJ
cord-341690-h8fqijk5	239	5	stomatitis	stomatitis	NN
cord-341690-h8fqijk5	239	6	virus	virus	NN
cord-341690-h8fqijk5	239	7	(	(	-LRB-
cord-341690-h8fqijk5	239	8	VSV	VSV	NNP
cord-341690-h8fqijk5	239	9	)	)	-RRB-
cord-341690-h8fqijk5	239	10	virions	virion	NNS
cord-341690-h8fqijk5	239	11	is	be	VBZ
cord-341690-h8fqijk5	239	12	enhanced	enhance	VBN
cord-341690-h8fqijk5	239	13	by	by	IN
cord-341690-h8fqijk5	239	14	the	the	DT
cord-341690-h8fqijk5	239	15	formation	formation	NN
cord-341690-h8fqijk5	239	16	of	of	IN
cord-341690-h8fqijk5	239	17	actin	actin	NN
cord-341690-h8fqijk5	239	18	filaments	filament	NNS
cord-341690-h8fqijk5	239	19	,	,	,
cord-341690-h8fqijk5	239	20	and	and	CC
cord-341690-h8fqijk5	239	21	actin	actin	NN
cord-341690-h8fqijk5	239	22	filaments	filament	NNS
cord-341690-h8fqijk5	239	23	are	be	VBP
cord-341690-h8fqijk5	239	24	recruited	recruit	VBN
cord-341690-h8fqijk5	239	25	to	to	TO
cord-341690-h8fqijk5	239	26	increase	increase	VB
cord-341690-h8fqijk5	239	27	the	the	DT
cord-341690-h8fqijk5	239	28	size	size	NN
cord-341690-h8fqijk5	239	29	of	of	IN
cord-341690-h8fqijk5	239	30	the	the	DT
cord-341690-h8fqijk5	239	31	endocytic	endocytic	JJ
cord-341690-h8fqijk5	239	32	structure	structure	NN
cord-341690-h8fqijk5	239	33	[	[	-LRB-
cord-341690-h8fqijk5	239	34	29	29	CD
cord-341690-h8fqijk5	239	35	]	]	-RRB-
cord-341690-h8fqijk5	239	36	.	.	.
cord-341690-h8fqijk5	240	1	Early	early	RB
cord-341690-h8fqijk5	240	2	in	in	IN
cord-341690-h8fqijk5	240	3	the	the	DT
cord-341690-h8fqijk5	240	4	infection	infection	NN
cord-341690-h8fqijk5	240	5	of	of	IN
cord-341690-h8fqijk5	240	6	TGEV	TGEV	NNP
cord-341690-h8fqijk5	240	7	,	,	,
cord-341690-h8fqijk5	240	8	we	-PRON-	PRP
cord-341690-h8fqijk5	240	9	observed	observe	VBD
cord-341690-h8fqijk5	240	10	the	the	DT
cord-341690-h8fqijk5	240	11	rearrangement	rearrangement	NN
cord-341690-h8fqijk5	240	12	of	of	IN
cord-341690-h8fqijk5	240	13	cortical	cortical	JJ
cord-341690-h8fqijk5	240	14	actin	actin	NN
cord-341690-h8fqijk5	240	15	and	and	CC
cord-341690-h8fqijk5	240	16	the	the	DT
cord-341690-h8fqijk5	240	17	formation	formation	NN
cord-341690-h8fqijk5	240	18	of	of	IN
cord-341690-h8fqijk5	240	19	ruffles	ruffle	NNS
cord-341690-h8fqijk5	240	20	and	and	CC
cord-341690-h8fqijk5	240	21	protrusions	protrusion	NNS
cord-341690-h8fqijk5	240	22	in	in	IN
cord-341690-h8fqijk5	240	23	the	the	DT
cord-341690-h8fqijk5	240	24	cell	cell	NN
cord-341690-h8fqijk5	240	25	membrane	membrane	NN
cord-341690-h8fqijk5	240	26	,	,	,
cord-341690-h8fqijk5	240	27	as	as	RB
cord-341690-h8fqijk5	240	28	well	well	RB
cord-341690-h8fqijk5	240	29	as	as	IN
cord-341690-h8fqijk5	240	30	EGFR	EGFR	NNP
cord-341690-h8fqijk5	240	31	and	and	CC
cord-341690-h8fqijk5	240	32	lipid	lipid	NN
cord-341690-h8fqijk5	240	33	rafts	raft	NNS
cord-341690-h8fqijk5	240	34	clustering	cluster	VBG
cord-341690-h8fqijk5	240	35	in	in	IN
cord-341690-h8fqijk5	240	36	the	the	DT
cord-341690-h8fqijk5	240	37	cell	cell	NN
cord-341690-h8fqijk5	240	38	membrane	membrane	NN
cord-341690-h8fqijk5	240	39	,	,	,
cord-341690-h8fqijk5	240	40	the	the	DT
cord-341690-h8fqijk5	240	41	dissolution	dissolution	NN
cord-341690-h8fqijk5	240	42	of	of	IN
cord-341690-h8fqijk5	240	43	actin	actin	JJ
cord-341690-h8fqijk5	240	44	stress	stress	NN
cord-341690-h8fqijk5	240	45	fibers	fiber	NNS
cord-341690-h8fqijk5	240	46	and	and	CC
cord-341690-h8fqijk5	240	47	their	-PRON-	PRP$
cord-341690-h8fqijk5	240	48	relocalization	relocalization	NN
cord-341690-h8fqijk5	240	49	around	around	IN
cord-341690-h8fqijk5	240	50	the	the	DT
cord-341690-h8fqijk5	240	51	cell	cell	NN
cord-341690-h8fqijk5	240	52	plasma	plasma	NN
cord-341690-h8fqijk5	240	53	membrane	membrane	NN
cord-341690-h8fqijk5	240	54	.	.	.
cord-341690-h8fqijk5	241	1	These	these	DT
cord-341690-h8fqijk5	241	2	changes	change	NNS
cord-341690-h8fqijk5	241	3	appear	appear	VBP
cord-341690-h8fqijk5	241	4	to	to	TO
cord-341690-h8fqijk5	241	5	mediate	mediate	VB
cord-341690-h8fqijk5	241	6	TGEV	TGEV	NNP
cord-341690-h8fqijk5	241	7	entry	entry	NN
cord-341690-h8fqijk5	241	8	.	.	.
cord-341690-h8fqijk5	242	1	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	242	2	has	have	VBZ
cord-341690-h8fqijk5	242	3	a	a	DT
cord-341690-h8fqijk5	242	4	central	central	JJ
cord-341690-h8fqijk5	242	5	role	role	NN
cord-341690-h8fqijk5	242	6	in	in	IN
cord-341690-h8fqijk5	242	7	controlling	control	VBG
cord-341690-h8fqijk5	242	8	actin	actin	NN
cord-341690-h8fqijk5	242	9	dynamics	dynamic	NNS
cord-341690-h8fqijk5	242	10	by	by	IN
cord-341690-h8fqijk5	242	11	regulating	regulate	VBG
cord-341690-h8fqijk5	242	12	actin	actin	NN
cord-341690-h8fqijk5	242	13	polymerization	polymerization	NN
cord-341690-h8fqijk5	242	14	and	and	CC
cord-341690-h8fqijk5	242	15	depolymerization	depolymerization	NN
cord-341690-h8fqijk5	242	16	through	through	IN
cord-341690-h8fqijk5	242	17	its	-PRON-	PRP$
cord-341690-h8fqijk5	242	18	severing	sever	VBG
cord-341690-h8fqijk5	242	19	activity	activity	NN
cord-341690-h8fqijk5	242	20	,	,	,
cord-341690-h8fqijk5	242	21	as	as	RB
cord-341690-h8fqijk5	242	22	well	well	RB
cord-341690-h8fqijk5	242	23	as	as	IN
cord-341690-h8fqijk5	242	24	by	by	IN
cord-341690-h8fqijk5	242	25	inducing	induce	VBG
cord-341690-h8fqijk5	242	26	dendritic	dendritic	JJ
cord-341690-h8fqijk5	242	27	nucleation	nucleation	NN
cord-341690-h8fqijk5	242	28	[	[	-LRB-
cord-341690-h8fqijk5	242	29	6	6	CD
cord-341690-h8fqijk5	242	30	]	]	-RRB-
cord-341690-h8fqijk5	242	31	.	.	.
cord-341690-h8fqijk5	243	1	The	the	DT
cord-341690-h8fqijk5	243	2	regulation	regulation	NN
cord-341690-h8fqijk5	243	3	of	of	IN
cord-341690-h8fqijk5	243	4	cofilin	cofilin	JJ
cord-341690-h8fqijk5	243	5	activity	activity	NN
cord-341690-h8fqijk5	243	6	is	be	VBZ
cord-341690-h8fqijk5	243	7	a	a	DT
cord-341690-h8fqijk5	243	8	component	component	NN
cord-341690-h8fqijk5	243	9	of	of	IN
cord-341690-h8fqijk5	243	10	pathogen	pathogen	NN
cord-341690-h8fqijk5	243	11	-	-	HYPH
cord-341690-h8fqijk5	243	12	mediated	mediate	VBN
cord-341690-h8fqijk5	243	13	actin	actin	NN
cord-341690-h8fqijk5	243	14	remodeling	remodeling	NN
cord-341690-h8fqijk5	243	15	[	[	-LRB-
cord-341690-h8fqijk5	243	16	30	30	CD
cord-341690-h8fqijk5	243	17	,	,	,
cord-341690-h8fqijk5	243	18	31	31	CD
cord-341690-h8fqijk5	243	19	]	]	-RRB-
cord-341690-h8fqijk5	243	20	.	.	.
cord-341690-h8fqijk5	244	1	We	-PRON-	PRP
cord-341690-h8fqijk5	244	2	conclude	conclude	VBP
cord-341690-h8fqijk5	244	3	that	that	IN
cord-341690-h8fqijk5	244	4	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	244	5	of	of	IN
cord-341690-h8fqijk5	244	6	cofilin	cofilin	NN
cord-341690-h8fqijk5	244	7	is	be	VBZ
cord-341690-h8fqijk5	244	8	critical	critical	JJ
cord-341690-h8fqijk5	244	9	for	for	IN
cord-341690-h8fqijk5	244	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	244	11	entry	entry	NN
cord-341690-h8fqijk5	244	12	.	.	.
cord-341690-h8fqijk5	245	1	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	245	2	can	can	MD
cord-341690-h8fqijk5	245	3	be	be	VB
cord-341690-h8fqijk5	245	4	found	find	VBN
cord-341690-h8fqijk5	245	5	in	in	IN
cord-341690-h8fqijk5	245	6	multiple	multiple	JJ
cord-341690-h8fqijk5	245	7	cellular	cellular	JJ
cord-341690-h8fqijk5	245	8	compartments	compartment	NNS
cord-341690-h8fqijk5	245	9	,	,	,
cord-341690-h8fqijk5	245	10	including	include	VBG
cord-341690-h8fqijk5	245	11	the	the	DT
cord-341690-h8fqijk5	245	12	cytoplasm	cytoplasm	NN
cord-341690-h8fqijk5	245	13	and	and	CC
cord-341690-h8fqijk5	245	14	nucleoplasm	nucleoplasm	NN
cord-341690-h8fqijk5	245	15	[	[	-LRB-
cord-341690-h8fqijk5	245	16	32	32	CD
cord-341690-h8fqijk5	245	17	,	,	,
cord-341690-h8fqijk5	245	18	33	33	CD
cord-341690-h8fqijk5	245	19	]	]	-RRB-
cord-341690-h8fqijk5	245	20	.	.	.
cord-341690-h8fqijk5	246	1	A	a	DT
cord-341690-h8fqijk5	246	2	nuclear	nuclear	JJ
cord-341690-h8fqijk5	246	3	localization	localization	NN
cord-341690-h8fqijk5	246	4	signal	signal	NN
cord-341690-h8fqijk5	246	5	(	(	-LRB-
cord-341690-h8fqijk5	246	6	amino	amino	NN
cord-341690-h8fqijk5	246	7	acid	acid	NN
cord-341690-h8fqijk5	246	8	residues	residue	NNS
cord-341690-h8fqijk5	246	9	30	30	CD
cord-341690-h8fqijk5	246	10	-	-	SYM
cord-341690-h8fqijk5	246	11	34	34	CD
cord-341690-h8fqijk5	246	12	)	)	-RRB-
cord-341690-h8fqijk5	246	13	with	with	IN
cord-341690-h8fqijk5	246	14	high	high	JJ
cord-341690-h8fqijk5	246	15	homology	homology	NN
cord-341690-h8fqijk5	246	16	to	to	IN
cord-341690-h8fqijk5	246	17	the	the	DT
cord-341690-h8fqijk5	246	18	consensus	consensus	NN
cord-341690-h8fqijk5	246	19	nuclear	nuclear	JJ
cord-341690-h8fqijk5	246	20	localization	localization	NN
cord-341690-h8fqijk5	246	21	signal	signal	NN
cord-341690-h8fqijk5	246	22	sequence	sequence	NN
cord-341690-h8fqijk5	246	23	of	of	IN
cord-341690-h8fqijk5	246	24	SV40	SV40	NNP
cord-341690-h8fqijk5	246	25	large	large	JJ
cord-341690-h8fqijk5	246	26	T	t	NN
cord-341690-h8fqijk5	246	27	-	-	HYPH
cord-341690-h8fqijk5	246	28	antigen	antigen	NN
cord-341690-h8fqijk5	246	29	is	be	VBZ
cord-341690-h8fqijk5	246	30	found	find	VBN
cord-341690-h8fqijk5	246	31	in	in	IN
cord-341690-h8fqijk5	246	32	the	the	DT
cord-341690-h8fqijk5	246	33	cofilin	cofilin	NN
cord-341690-h8fqijk5	246	34	sequence	sequence	NN
cord-341690-h8fqijk5	246	35	[	[	-LRB-
cord-341690-h8fqijk5	246	36	34	34	CD
cord-341690-h8fqijk5	246	37	]	]	-RRB-
cord-341690-h8fqijk5	246	38	.	.	.
cord-341690-h8fqijk5	247	1	The	the	DT
cord-341690-h8fqijk5	247	2	nuclear	nuclear	JJ
cord-341690-h8fqijk5	247	3	translocation	translocation	NN
cord-341690-h8fqijk5	247	4	of	of	IN
cord-341690-h8fqijk5	247	5	cofilin	cofilin	NNP
cord-341690-h8fqijk5	247	6	is	be	VBZ
cord-341690-h8fqijk5	247	7	regulated	regulate	VBN
cord-341690-h8fqijk5	247	8	by	by	IN
cord-341690-h8fqijk5	247	9	reversible	reversible	JJ
cord-341690-h8fqijk5	247	10	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	247	11	of	of	IN
cord-341690-h8fqijk5	247	12	Ser-3	Ser-3	NNP
cord-341690-h8fqijk5	247	13	[	[	-LRB-
cord-341690-h8fqijk5	247	14	35	35	CD
cord-341690-h8fqijk5	247	15	]	]	-RRB-
cord-341690-h8fqijk5	247	16	.	.	.
cord-341690-h8fqijk5	248	1	The	the	DT
cord-341690-h8fqijk5	248	2	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	248	3	of	of	IN
cord-341690-h8fqijk5	248	4	cofilin	cofilin	NN
cord-341690-h8fqijk5	248	5	inhibits	inhibit	VBZ
cord-341690-h8fqijk5	248	6	its	-PRON-	PRP$
cord-341690-h8fqijk5	248	7	F	F	NNP
cord-341690-h8fqijk5	248	8	-	-	HYPH
cord-341690-h8fqijk5	248	9	actin	actin	JJ
cord-341690-h8fqijk5	248	10	severing	severing	NN
cord-341690-h8fqijk5	248	11	activity	activity	NN
cord-341690-h8fqijk5	248	12	.	.	.
cord-341690-h8fqijk5	249	1	We	-PRON-	PRP
cord-341690-h8fqijk5	249	2	found	find	VBD
cord-341690-h8fqijk5	249	3	that	that	IN
cord-341690-h8fqijk5	249	4	p	p	NN
cord-341690-h8fqijk5	249	5	-	-	:
cord-341690-h8fqijk5	249	6	cofilin	cofilin	NN
cord-341690-h8fqijk5	249	7	was	be	VBD
cord-341690-h8fqijk5	249	8	distributed	distribute	VBN
cord-341690-h8fqijk5	249	9	mainly	mainly	RB
cord-341690-h8fqijk5	249	10	in	in	IN
cord-341690-h8fqijk5	249	11	the	the	DT
cord-341690-h8fqijk5	249	12	nucleus	nucleus	NN
cord-341690-h8fqijk5	249	13	of	of	IN
cord-341690-h8fqijk5	249	14	normal	normal	JJ
cord-341690-h8fqijk5	249	15	IPEC	IPEC	NNP
cord-341690-h8fqijk5	249	16	-	-	HYPH
cord-341690-h8fqijk5	249	17	J2	j2	NN
cord-341690-h8fqijk5	249	18	cells	cell	NNS
cord-341690-h8fqijk5	249	19	,	,	,
cord-341690-h8fqijk5	249	20	however	however	RB
cord-341690-h8fqijk5	249	21	,	,	,
cord-341690-h8fqijk5	249	22	early	early	RB
cord-341690-h8fqijk5	249	23	after	after	IN
cord-341690-h8fqijk5	249	24	TGEV	TGEV	NNP
cord-341690-h8fqijk5	249	25	infection	infection	NN
cord-341690-h8fqijk5	249	26	,	,	,
cord-341690-h8fqijk5	249	27	most	most	JJS
cord-341690-h8fqijk5	249	28	p	p	NN
cord-341690-h8fqijk5	249	29	-	-	:
cord-341690-h8fqijk5	249	30	cofilin	cofilin	NNP
cord-341690-h8fqijk5	249	31	was	be	VBD
cord-341690-h8fqijk5	249	32	found	find	VBN
cord-341690-h8fqijk5	249	33	in	in	IN
cord-341690-h8fqijk5	249	34	the	the	DT
cord-341690-h8fqijk5	249	35	plasma	plasma	NN
cord-341690-h8fqijk5	249	36	membrane	membrane	NN
cord-341690-h8fqijk5	249	37	,	,	,
cord-341690-h8fqijk5	249	38	derived	derive	VBD
cord-341690-h8fqijk5	249	39	both	both	CC
cord-341690-h8fqijk5	249	40	from	from	IN
cord-341690-h8fqijk5	249	41	the	the	DT
cord-341690-h8fqijk5	249	42	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	249	43	of	of	IN
cord-341690-h8fqijk5	249	44	cofilin	cofilin	NN
cord-341690-h8fqijk5	249	45	and	and	CC
cord-341690-h8fqijk5	249	46	the	the	DT
cord-341690-h8fqijk5	249	47	migration	migration	NN
cord-341690-h8fqijk5	249	48	of	of	IN
cord-341690-h8fqijk5	249	49	p	p	NN
cord-341690-h8fqijk5	249	50	-	-	NN
cord-341690-h8fqijk5	249	51	cofilin	cofilin	NN
cord-341690-h8fqijk5	249	52	from	from	IN
cord-341690-h8fqijk5	249	53	the	the	DT
cord-341690-h8fqijk5	249	54	nucleus	nucleus	NN
cord-341690-h8fqijk5	249	55	.	.	.
cord-341690-h8fqijk5	250	1	Late	late	RB
cord-341690-h8fqijk5	250	2	in	in	IN
cord-341690-h8fqijk5	250	3	infection	infection	NN
cord-341690-h8fqijk5	250	4	,	,	,
cord-341690-h8fqijk5	250	5	a	a	DT
cord-341690-h8fqijk5	250	6	portion	portion	NN
cord-341690-h8fqijk5	250	7	of	of	IN
cord-341690-h8fqijk5	250	8	the	the	DT
cord-341690-h8fqijk5	250	9	p	p	NN
cord-341690-h8fqijk5	250	10	-	-	:
cord-341690-h8fqijk5	250	11	cofilin	cofilin	NNP
cord-341690-h8fqijk5	250	12	was	be	VBD
cord-341690-h8fqijk5	250	13	dephosphorylated	dephosphorylate	VBN
cord-341690-h8fqijk5	250	14	,	,	,
cord-341690-h8fqijk5	250	15	while	while	IN
cord-341690-h8fqijk5	250	16	the	the	DT
cord-341690-h8fqijk5	250	17	remaining	remain	VBG
cord-341690-h8fqijk5	250	18	p	p	NN
cord-341690-h8fqijk5	250	19	-	-	HYPH
cord-341690-h8fqijk5	250	20	cofilin	cofilin	NN
cord-341690-h8fqijk5	250	21	returned	return	VBD
cord-341690-h8fqijk5	250	22	to	to	IN
cord-341690-h8fqijk5	250	23	the	the	DT
cord-341690-h8fqijk5	250	24	nucleus	nucleus	NN
cord-341690-h8fqijk5	250	25	.	.	.
cord-341690-h8fqijk5	251	1	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	251	2	supports	support	VBZ
cord-341690-h8fqijk5	251	3	ARP2/3	ARP2/3	NNP
cord-341690-h8fqijk5	251	4	complex	complex	RB
cord-341690-h8fqijk5	251	5	-	-	HYPH
cord-341690-h8fqijk5	251	6	mediated	mediate	VBN
cord-341690-h8fqijk5	251	7	actin	actin	NN
cord-341690-h8fqijk5	251	8	branching	branch	VBG
cord-341690-h8fqijk5	251	9	by	by	IN
cord-341690-h8fqijk5	251	10	creating	create	VBG
cord-341690-h8fqijk5	251	11	new	new	JJ
cord-341690-h8fqijk5	251	12	actin	actin	NN
cord-341690-h8fqijk5	251	13	filaments	filament	NNS
cord-341690-h8fqijk5	251	14	through	through	IN
cord-341690-h8fqijk5	251	15	its	-PRON-	PRP$
cord-341690-h8fqijk5	251	16	F	f	NN
cord-341690-h8fqijk5	251	17	-	-	HYPH
cord-341690-h8fqijk5	251	18	actin	actin	JJ
cord-341690-h8fqijk5	251	19	severing	severing	NN
cord-341690-h8fqijk5	251	20	activity	activity	NN
cord-341690-h8fqijk5	251	21	,	,	,
cord-341690-h8fqijk5	251	22	making	make	VBG
cord-341690-h8fqijk5	251	23	the	the	DT
cord-341690-h8fqijk5	251	24	actin	actin	NN
cord-341690-h8fqijk5	251	25	filaments	filament	NNS
cord-341690-h8fqijk5	251	26	more	more	RBR
cord-341690-h8fqijk5	251	27	stable	stable	JJ
cord-341690-h8fqijk5	251	28	at	at	IN
cord-341690-h8fqijk5	251	29	the	the	DT
cord-341690-h8fqijk5	251	30	cell	cell	NN
cord-341690-h8fqijk5	251	31	membrane	membrane	NN
cord-341690-h8fqijk5	251	32	[	[	-LRB-
cord-341690-h8fqijk5	251	33	36	36	CD
cord-341690-h8fqijk5	251	34	]	]	-RRB-
cord-341690-h8fqijk5	251	35	.	.	.
cord-341690-h8fqijk5	252	1	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	252	2	is	be	VBZ
cord-341690-h8fqijk5	252	3	required	require	VBN
cord-341690-h8fqijk5	252	4	for	for	IN
cord-341690-h8fqijk5	252	5	the	the	DT
cord-341690-h8fqijk5	252	6	early	early	JJ
cord-341690-h8fqijk5	252	7	polymerization	polymerization	NN
cord-341690-h8fqijk5	252	8	response	response	NN
cord-341690-h8fqijk5	252	9	to	to	IN
cord-341690-h8fqijk5	252	10	growth	growth	NN
cord-341690-h8fqijk5	252	11	factor	factor	NN
cord-341690-h8fqijk5	252	12	stimulation	stimulation	NN
cord-341690-h8fqijk5	252	13	and	and	CC
cord-341690-h8fqijk5	252	14	the	the	DT
cord-341690-h8fqijk5	252	15	formation	formation	NN
cord-341690-h8fqijk5	252	16	of	of	IN
cord-341690-h8fqijk5	252	17	protrusions	protrusion	NNS
cord-341690-h8fqijk5	252	18	,	,	,
cord-341690-h8fqijk5	252	19	although	although	IN
cord-341690-h8fqijk5	252	20	the	the	DT
cord-341690-h8fqijk5	252	21	ARP2/3	ARP2/3	NNP
cord-341690-h8fqijk5	252	22	complex	complex	NN
cord-341690-h8fqijk5	252	23	is	be	VBZ
cord-341690-h8fqijk5	252	24	not	not	RB
cord-341690-h8fqijk5	252	25	involved	involve	VBN
cord-341690-h8fqijk5	252	26	in	in	IN
cord-341690-h8fqijk5	252	27	this	this	DT
cord-341690-h8fqijk5	252	28	process	process	NN
cord-341690-h8fqijk5	252	29	[	[	-LRB-
cord-341690-h8fqijk5	252	30	37	37	CD
cord-341690-h8fqijk5	252	31	,	,	,
cord-341690-h8fqijk5	252	32	38	38	CD
cord-341690-h8fqijk5	252	33	]	]	-RRB-
cord-341690-h8fqijk5	252	34	.	.	.
cord-341690-h8fqijk5	253	1	The	the	DT
cord-341690-h8fqijk5	253	2	inhibition	inhibition	NN
cord-341690-h8fqijk5	253	3	of	of	IN
cord-341690-h8fqijk5	253	4	ARP2/3	ARP2/3	NNP
cord-341690-h8fqijk5	253	5	caused	cause	VBD
cord-341690-h8fqijk5	253	6	the	the	DT
cord-341690-h8fqijk5	253	7	actin	actin	NN
cord-341690-h8fqijk5	253	8	filaments	filament	NNS
cord-341690-h8fqijk5	253	9	to	to	TO
cord-341690-h8fqijk5	253	10	bind	bind	VB
cord-341690-h8fqijk5	253	11	together	together	RB
cord-341690-h8fqijk5	253	12	more	more	RBR
cord-341690-h8fqijk5	253	13	loosely	loosely	RB
cord-341690-h8fqijk5	253	14	,	,	,
cord-341690-h8fqijk5	253	15	resulting	result	VBG
cord-341690-h8fqijk5	253	16	in	in	IN
cord-341690-h8fqijk5	253	17	increased	increase	VBN
cord-341690-h8fqijk5	253	18	entry	entry	NN
cord-341690-h8fqijk5	253	19	of	of	IN
cord-341690-h8fqijk5	253	20	TGEV	TGEV	NNS
cord-341690-h8fqijk5	253	21	.	.	.
cord-341690-h8fqijk5	254	1	We	-PRON-	PRP
cord-341690-h8fqijk5	254	2	conclude	conclude	VBP
cord-341690-h8fqijk5	254	3	that	that	IN
cord-341690-h8fqijk5	254	4	the	the	DT
cord-341690-h8fqijk5	254	5	structure	structure	NN
cord-341690-h8fqijk5	254	6	of	of	IN
cord-341690-h8fqijk5	254	7	the	the	DT
cord-341690-h8fqijk5	254	8	cortical	cortical	JJ
cord-341690-h8fqijk5	254	9	actin	actin	NN
cord-341690-h8fqijk5	254	10	filaments	filament	NNS
cord-341690-h8fqijk5	254	11	,	,	,
cord-341690-h8fqijk5	254	12	which	which	WDT
cord-341690-h8fqijk5	254	13	underline	underline	VBP
cord-341690-h8fqijk5	254	14	the	the	DT
cord-341690-h8fqijk5	254	15	cell	cell	NN
cord-341690-h8fqijk5	254	16	membrane	membrane	NN
cord-341690-h8fqijk5	254	17	,	,	,
cord-341690-h8fqijk5	254	18	plays	play	VBZ
cord-341690-h8fqijk5	254	19	an	an	DT
cord-341690-h8fqijk5	254	20	important	important	JJ
cord-341690-h8fqijk5	254	21	role	role	NN
cord-341690-h8fqijk5	254	22	in	in	IN
cord-341690-h8fqijk5	254	23	TGEV	TGEV	NNP
cord-341690-h8fqijk5	254	24	early	early	JJ
cord-341690-h8fqijk5	254	25	infection	infection	NN
cord-341690-h8fqijk5	254	26	.	.	.
cord-341690-h8fqijk5	255	1	The	the	DT
cord-341690-h8fqijk5	255	2	regulation	regulation	NN
cord-341690-h8fqijk5	255	3	of	of	IN
cord-341690-h8fqijk5	255	4	cofilin	cofilin	JJ
cord-341690-h8fqijk5	255	5	activity	activity	NN
cord-341690-h8fqijk5	255	6	acts	act	VBZ
cord-341690-h8fqijk5	255	7	as	as	IN
cord-341690-h8fqijk5	255	8	a	a	DT
cord-341690-h8fqijk5	255	9	molecular	molecular	JJ
cord-341690-h8fqijk5	255	10	switch	switch	NN
cord-341690-h8fqijk5	255	11	to	to	TO
cord-341690-h8fqijk5	255	12	provide	provide	VB
cord-341690-h8fqijk5	255	13	a	a	DT
cord-341690-h8fqijk5	255	14	functional	functional	JJ
cord-341690-h8fqijk5	255	15	link	link	NN
cord-341690-h8fqijk5	255	16	between	between	IN
cord-341690-h8fqijk5	255	17	actin	actin	NN
cord-341690-h8fqijk5	255	18	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	255	19	rearrangement	rearrangement	NN
cord-341690-h8fqijk5	255	20	and	and	CC
cord-341690-h8fqijk5	255	21	the	the	DT
cord-341690-h8fqijk5	255	22	TGEV	TGEV	NNP
cord-341690-h8fqijk5	255	23	entry	entry	NN
cord-341690-h8fqijk5	255	24	process	process	NN
cord-341690-h8fqijk5	255	25	.	.	.
cord-341690-h8fqijk5	256	1	The	the	DT
cord-341690-h8fqijk5	256	2	actin	actin	NN
cord-341690-h8fqijk5	256	3	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	256	4	is	be	VBZ
cord-341690-h8fqijk5	256	5	mainly	mainly	RB
cord-341690-h8fqijk5	256	6	regulated	regulate	VBN
cord-341690-h8fqijk5	256	7	by	by	IN
cord-341690-h8fqijk5	256	8	RHOfamily	rhofamily	NN
cord-341690-h8fqijk5	256	9	-	-	HYPH
cord-341690-h8fqijk5	256	10	GTPases	gtpase	NNS
cord-341690-h8fqijk5	256	11	,	,	,
cord-341690-h8fqijk5	256	12	which	which	WDT
cord-341690-h8fqijk5	256	13	control	control	VBP
cord-341690-h8fqijk5	256	14	the	the	DT
cord-341690-h8fqijk5	256	15	signaling	signal	VBG
cord-341690-h8fqijk5	256	16	pathway	pathway	NN
cord-341690-h8fqijk5	256	17	that	that	WDT
cord-341690-h8fqijk5	256	18	links	link	VBZ
cord-341690-h8fqijk5	256	19	membrane	membrane	NN
cord-341690-h8fqijk5	256	20	receptors	receptor	NNS
cord-341690-h8fqijk5	256	21	to	to	IN
cord-341690-h8fqijk5	256	22	the	the	DT
cord-341690-h8fqijk5	256	23	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	256	24	[	[	-LRB-
cord-341690-h8fqijk5	256	25	4	4	CD
cord-341690-h8fqijk5	256	26	]	]	-RRB-
cord-341690-h8fqijk5	256	27	.	.	.
cord-341690-h8fqijk5	257	1	The	the	DT
cord-341690-h8fqijk5	257	2	RHO	RHO	NNP
cord-341690-h8fqijk5	257	3	family	family	NN
cord-341690-h8fqijk5	257	4	of	of	IN
cord-341690-h8fqijk5	257	5	GTPases	gtpase	NNS
cord-341690-h8fqijk5	257	6	contain	contain	VBP
cord-341690-h8fqijk5	257	7	more	more	JJR
cord-341690-h8fqijk5	257	8	than	than	IN
cord-341690-h8fqijk5	257	9	twenty	twenty	CD
cord-341690-h8fqijk5	257	10	members	member	NNS
cord-341690-h8fqijk5	257	11	.	.	.
cord-341690-h8fqijk5	258	1	Rac1	Rac1	NNP
cord-341690-h8fqijk5	258	2	,	,	,
cord-341690-h8fqijk5	258	3	a	a	DT
cord-341690-h8fqijk5	258	4	primary	primary	JJ
cord-341690-h8fqijk5	258	5	example	example	NN
cord-341690-h8fqijk5	258	6	,	,	,
cord-341690-h8fqijk5	258	7	induces	induce	VBZ
cord-341690-h8fqijk5	258	8	membrane	membrane	NN
cord-341690-h8fqijk5	258	9	ruffles	ruffle	NNS
cord-341690-h8fqijk5	258	10	or	or	CC
cord-341690-h8fqijk5	258	11	lamellipodia	lamellipodia	NNP
cord-341690-h8fqijk5	258	12	[	[	-LRB-
cord-341690-h8fqijk5	258	13	39	39	CD
cord-341690-h8fqijk5	258	14	]	]	-RRB-
cord-341690-h8fqijk5	258	15	.	.	.
cord-341690-h8fqijk5	259	1	PI3	PI3	NNP
cord-341690-h8fqijk5	259	2	K	K	NNP
cord-341690-h8fqijk5	260	1	/Akt	/Akt	NNP
cord-341690-h8fqijk5	260	2	is	be	VBZ
cord-341690-h8fqijk5	260	3	the	the	DT
cord-341690-h8fqijk5	260	4	main	main	JJ
cord-341690-h8fqijk5	260	5	activation	activation	NN
cord-341690-h8fqijk5	260	6	pathway	pathway	NN
cord-341690-h8fqijk5	260	7	for	for	IN
cord-341690-h8fqijk5	260	8	Rac1	Rac1	NNP
cord-341690-h8fqijk5	260	9	in	in	IN
cord-341690-h8fqijk5	260	10	many	many	JJ
cord-341690-h8fqijk5	260	11	cell	cell	NN
cord-341690-h8fqijk5	260	12	types	type	NNS
cord-341690-h8fqijk5	260	13	[	[	-LRB-
cord-341690-h8fqijk5	260	14	40	40	CD
cord-341690-h8fqijk5	260	15	]	]	-RRB-
cord-341690-h8fqijk5	260	16	.	.	.
cord-341690-h8fqijk5	261	1	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	261	2	is	be	VBZ
cord-341690-h8fqijk5	261	3	inactivated	inactivate	VBN
cord-341690-h8fqijk5	261	4	by	by	IN
cord-341690-h8fqijk5	261	5	Rac1	Rac1	NNP
cord-341690-h8fqijk5	261	6	and	and	CC
cord-341690-h8fqijk5	261	7	Cdc42	Cdc42	NNP
cord-341690-h8fqijk5	261	8	through	through	IN
cord-341690-h8fqijk5	261	9	PAK	PAK	NNP
cord-341690-h8fqijk5	261	10	and	and	CC
cord-341690-h8fqijk5	261	11	LIMK	LIMK	NNP
cord-341690-h8fqijk5	261	12	.	.	.
cord-341690-h8fqijk5	262	1	The	the	DT
cord-341690-h8fqijk5	262	2	entry	entry	NN
cord-341690-h8fqijk5	262	3	of	of	IN
cord-341690-h8fqijk5	262	4	Ebola	Ebola	NNP
cord-341690-h8fqijk5	262	5	virions	virion	NNS
cord-341690-h8fqijk5	262	6	and	and	CC
cord-341690-h8fqijk5	262	7	VSV	VSV	NNP
cord-341690-h8fqijk5	262	8	pseudovirions	pseudovirion	NNS
cord-341690-h8fqijk5	262	9	are	be	VBP
cord-341690-h8fqijk5	262	10	decreased	decrease	VBN
cord-341690-h8fqijk5	262	11	when	when	WRB
cord-341690-h8fqijk5	262	12	RhoA	RhoA	NNP
cord-341690-h8fqijk5	262	13	is	be	VBZ
cord-341690-h8fqijk5	262	14	overexpressed	overexpresse	VBN
cord-341690-h8fqijk5	262	15	[	[	-LRB-
cord-341690-h8fqijk5	262	16	41	41	CD
cord-341690-h8fqijk5	262	17	]	]	-RRB-
cord-341690-h8fqijk5	262	18	.	.	.
cord-341690-h8fqijk5	263	1	RhoA	RhoA	NNP
cord-341690-h8fqijk5	263	2	activation	activation	NN
cord-341690-h8fqijk5	263	3	by	by	IN
cord-341690-h8fqijk5	263	4	PI3	PI3	NNP
cord-341690-h8fqijk5	263	5	K	K	NNP
cord-341690-h8fqijk5	263	6	leads	lead	VBZ
cord-341690-h8fqijk5	263	7	to	to	IN
cord-341690-h8fqijk5	263	8	the	the	DT
cord-341690-h8fqijk5	263	9	formation	formation	NN
cord-341690-h8fqijk5	263	10	of	of	IN
cord-341690-h8fqijk5	263	11	stress	stress	NN
cord-341690-h8fqijk5	263	12	fibers	fiber	NNS
cord-341690-h8fqijk5	263	13	[	[	-LRB-
cord-341690-h8fqijk5	263	14	4	4	CD
cord-341690-h8fqijk5	263	15	]	]	-RRB-
cord-341690-h8fqijk5	263	16	.	.	.
cord-341690-h8fqijk5	264	1	Constitutively	Constitutively	NNP
cord-341690-h8fqijk5	264	2	activated	activate	VBD
cord-341690-h8fqijk5	264	3	mutant	mutant	NN
cord-341690-h8fqijk5	264	4	L63RhoA	L63RhoA	NNP
cord-341690-h8fqijk5	264	5	caused	cause	VBD
cord-341690-h8fqijk5	264	6	the	the	DT
cord-341690-h8fqijk5	264	7	formation	formation	NN
cord-341690-h8fqijk5	264	8	of	of	IN
cord-341690-h8fqijk5	264	9	stress	stress	NN
cord-341690-h8fqijk5	264	10	fibers	fiber	NNS
cord-341690-h8fqijk5	264	11	,	,	,
cord-341690-h8fqijk5	264	12	and	and	CC
cord-341690-h8fqijk5	264	13	prevented	prevent	VBD
cord-341690-h8fqijk5	264	14	the	the	DT
cord-341690-h8fqijk5	264	15	destruction	destruction	NN
cord-341690-h8fqijk5	264	16	of	of	IN
cord-341690-h8fqijk5	264	17	stress	stress	NN
cord-341690-h8fqijk5	264	18	fibers	fiber	NNS
cord-341690-h8fqijk5	264	19	caused	cause	VBN
cord-341690-h8fqijk5	264	20	by	by	IN
cord-341690-h8fqijk5	264	21	TGEV	TGEV	NNP
cord-341690-h8fqijk5	264	22	and	and	CC
cord-341690-h8fqijk5	264	23	reduced	reduce	VBD
cord-341690-h8fqijk5	264	24	the	the	DT
cord-341690-h8fqijk5	264	25	amount	amount	NN
cord-341690-h8fqijk5	264	26	of	of	IN
cord-341690-h8fqijk5	264	27	F	F	NNP
cord-341690-h8fqijk5	264	28	-	-	HYPH
cord-341690-h8fqijk5	264	29	actin	actin	NNP
cord-341690-h8fqijk5	264	30	gathered	gather	VBD
cord-341690-h8fqijk5	264	31	around	around	IN
cord-341690-h8fqijk5	264	32	the	the	DT
cord-341690-h8fqijk5	264	33	cell	cell	NN
cord-341690-h8fqijk5	264	34	membrane	membrane	NN
cord-341690-h8fqijk5	264	35	.	.	.
cord-341690-h8fqijk5	265	1	The	the	DT
cord-341690-h8fqijk5	265	2	inhibition	inhibition	NN
cord-341690-h8fqijk5	265	3	of	of	IN
cord-341690-h8fqijk5	265	4	ROCK	ROCK	NNP
cord-341690-h8fqijk5	265	5	had	have	VBD
cord-341690-h8fqijk5	265	6	no	no	DT
cord-341690-h8fqijk5	265	7	effect	effect	NN
cord-341690-h8fqijk5	265	8	on	on	IN
cord-341690-h8fqijk5	265	9	the	the	DT
cord-341690-h8fqijk5	265	10	entry	entry	NN
cord-341690-h8fqijk5	265	11	of	of	IN
cord-341690-h8fqijk5	265	12	TGEV	TGEV	NNP
cord-341690-h8fqijk5	265	13	or	or	CC
cord-341690-h8fqijk5	265	14	the	the	DT
cord-341690-h8fqijk5	265	15	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	265	16	of	of	IN
cord-341690-h8fqijk5	265	17	cofilin	cofilin	NN
cord-341690-h8fqijk5	265	18	.	.	.
cord-341690-h8fqijk5	266	1	Both	both	DT
cord-341690-h8fqijk5	266	2	constitutively	constitutively	RB
cord-341690-h8fqijk5	266	3	inactivated	inactivate	VBN
cord-341690-h8fqijk5	266	4	mutant	mutant	JJ
cord-341690-h8fqijk5	266	5	N17Rac1	N17Rac1	NNP
cord-341690-h8fqijk5	266	6	and	and	CC
cord-341690-h8fqijk5	266	7	constitutively	constitutively	RB
cord-341690-h8fqijk5	266	8	activated	activate	VBN
cord-341690-h8fqijk5	266	9	mutant	mutant	JJ
cord-341690-h8fqijk5	266	10	L61Rac1	L61Rac1	NNP
cord-341690-h8fqijk5	266	11	impeded	impede	VBD
cord-341690-h8fqijk5	266	12	the	the	DT
cord-341690-h8fqijk5	266	13	formation	formation	NN
cord-341690-h8fqijk5	266	14	of	of	IN
cord-341690-h8fqijk5	266	15	lamellipodia	lamellipodia	NNP
cord-341690-h8fqijk5	266	16	and	and	CC
cord-341690-h8fqijk5	266	17	membrane	membrane	NN
cord-341690-h8fqijk5	266	18	ruffles	ruffle	NNS
cord-341690-h8fqijk5	266	19	,	,	,
cord-341690-h8fqijk5	266	20	and	and	CC
cord-341690-h8fqijk5	266	21	both	both	DT
cord-341690-h8fqijk5	266	22	constitutively	constitutively	RB
cord-341690-h8fqijk5	266	23	inactivated	inactivate	VBN
cord-341690-h8fqijk5	266	24	mutant	mutant	JJ
cord-341690-h8fqijk5	266	25	N17Cdc42	N17Cdc42	NNP
cord-341690-h8fqijk5	266	26	and	and	CC
cord-341690-h8fqijk5	266	27	constitutively	constitutively	RB
cord-341690-h8fqijk5	266	28	activated	activate	VBN
cord-341690-h8fqijk5	266	29	mutant	mutant	JJ
cord-341690-h8fqijk5	266	30	L61Cdc42	L61Cdc42	NNS
cord-341690-h8fqijk5	266	31	impeded	impede	VBD
cord-341690-h8fqijk5	266	32	the	the	DT
cord-341690-h8fqijk5	266	33	formation	formation	NN
cord-341690-h8fqijk5	266	34	of	of	IN
cord-341690-h8fqijk5	266	35	protrusive	protrusive	JJ
cord-341690-h8fqijk5	266	36	filopodia	filopodia	NNS
cord-341690-h8fqijk5	266	37	.	.	.
cord-341690-h8fqijk5	267	1	These	these	DT
cord-341690-h8fqijk5	267	2	effects	effect	NNS
cord-341690-h8fqijk5	267	3	inhibited	inhibit	VBN
cord-341690-h8fqijk5	267	4	TGEV	TGEV	NNP
cord-341690-h8fqijk5	267	5	entry	entry	NN
cord-341690-h8fqijk5	267	6	.	.	.
cord-341690-h8fqijk5	268	1	The	the	DT
cord-341690-h8fqijk5	268	2	activation	activation	NN
cord-341690-h8fqijk5	268	3	of	of	IN
cord-341690-h8fqijk5	268	4	the	the	DT
cord-341690-h8fqijk5	268	5	PI3	PI3	NNP
cord-341690-h8fqijk5	268	6	K	K	NNP
cord-341690-h8fqijk5	268	7	signaling	signal	VBG
cord-341690-h8fqijk5	268	8	pathway	pathway	NN
cord-341690-h8fqijk5	268	9	is	be	VBZ
cord-341690-h8fqijk5	268	10	involved	involve	VBN
cord-341690-h8fqijk5	268	11	in	in	IN
cord-341690-h8fqijk5	268	12	the	the	DT
cord-341690-h8fqijk5	268	13	early	early	JJ
cord-341690-h8fqijk5	268	14	steps	step	NNS
cord-341690-h8fqijk5	268	15	of	of	IN
cord-341690-h8fqijk5	268	16	virus	virus	NN
cord-341690-h8fqijk5	268	17	infection	infection	NN
cord-341690-h8fqijk5	268	18	,	,	,
cord-341690-h8fqijk5	268	19	such	such	JJ
cord-341690-h8fqijk5	268	20	as	as	IN
cord-341690-h8fqijk5	268	21	receptor	receptor	NN
cord-341690-h8fqijk5	268	22	/	/	SYM
cord-341690-h8fqijk5	268	23	co	co	NN
cord-341690-h8fqijk5	268	24	-	-	JJ
cord-341690-h8fqijk5	268	25	receptor	receptor	JJ
cord-341690-h8fqijk5	268	26	engagement	engagement	NN
cord-341690-h8fqijk5	268	27	and	and	CC
cord-341690-h8fqijk5	268	28	virus	virus	NN
cord-341690-h8fqijk5	268	29	internalization	internalization	NN
cord-341690-h8fqijk5	268	30	[	[	-LRB-
cord-341690-h8fqijk5	268	31	42	42	CD
cord-341690-h8fqijk5	268	32	]	]	-RRB-
cord-341690-h8fqijk5	268	33	.	.	.
cord-341690-h8fqijk5	269	1	PI3	PI3	NNP
cord-341690-h8fqijk5	269	2	K	K	NNP
cord-341690-h8fqijk5	269	3	is	be	VBZ
cord-341690-h8fqijk5	269	4	a	a	DT
cord-341690-h8fqijk5	269	5	key	key	JJ
cord-341690-h8fqijk5	269	6	mediator	mediator	NN
cord-341690-h8fqijk5	269	7	of	of	IN
cord-341690-h8fqijk5	269	8	the	the	DT
cord-341690-h8fqijk5	269	9	signaling	signal	VBG
cord-341690-h8fqijk5	269	10	pathway	pathway	NN
cord-341690-h8fqijk5	269	11	that	that	WDT
cord-341690-h8fqijk5	269	12	regulates	regulate	VBZ
cord-341690-h8fqijk5	269	13	actin	actin	NN
cord-341690-h8fqijk5	269	14	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	269	15	reorganization	reorganization	NN
cord-341690-h8fqijk5	269	16	and	and	CC
cord-341690-h8fqijk5	269	17	polarized	polarized	JJ
cord-341690-h8fqijk5	269	18	cell	cell	NN
cord-341690-h8fqijk5	269	19	migration	migration	NN
cord-341690-h8fqijk5	269	20	[	[	-LRB-
cord-341690-h8fqijk5	269	21	7	7	CD
cord-341690-h8fqijk5	269	22	]	]	-RRB-
cord-341690-h8fqijk5	269	23	.	.	.
cord-341690-h8fqijk5	270	1	This	this	DT
cord-341690-h8fqijk5	270	2	study	study	NN
cord-341690-h8fqijk5	270	3	shows	show	VBZ
cord-341690-h8fqijk5	270	4	that	that	IN
cord-341690-h8fqijk5	270	5	the	the	DT
cord-341690-h8fqijk5	270	6	PI3K	PI3K	NNP
cord-341690-h8fqijk5	270	7	/	/	SYM
cord-341690-h8fqijk5	270	8	Akt	Akt	NNP
cord-341690-h8fqijk5	270	9	pathway	pathway	NN
cord-341690-h8fqijk5	270	10	is	be	VBZ
cord-341690-h8fqijk5	270	11	involved	involve	VBN
cord-341690-h8fqijk5	270	12	in	in	IN
cord-341690-h8fqijk5	270	13	the	the	DT
cord-341690-h8fqijk5	270	14	cellular	cellular	JJ
cord-341690-h8fqijk5	270	15	entry	entry	NN
cord-341690-h8fqijk5	270	16	of	of	IN
cord-341690-h8fqijk5	270	17	TGEV	TGEV	NNP
cord-341690-h8fqijk5	270	18	,	,	,
cord-341690-h8fqijk5	270	19	and	and	CC
cord-341690-h8fqijk5	270	20	is	be	VBZ
cord-341690-h8fqijk5	270	21	activated	activate	VBN
cord-341690-h8fqijk5	270	22	by	by	IN
cord-341690-h8fqijk5	270	23	EGFR	EGFR	NNP
cord-341690-h8fqijk5	270	24	.	.	.
cord-341690-h8fqijk5	271	1	Our	-PRON-	PRP$
cord-341690-h8fqijk5	271	2	previous	previous	JJ
cord-341690-h8fqijk5	271	3	studies	study	NNS
cord-341690-h8fqijk5	271	4	indicate	indicate	VBP
cord-341690-h8fqijk5	271	5	that	that	IN
cord-341690-h8fqijk5	271	6	MAPK	MAPK	NNP
cord-341690-h8fqijk5	271	7	pathways	pathway	NNS
cord-341690-h8fqijk5	271	8	are	be	VBP
cord-341690-h8fqijk5	271	9	activated	activate	VBN
cord-341690-h8fqijk5	271	10	early	early	RB
cord-341690-h8fqijk5	271	11	in	in	IN
cord-341690-h8fqijk5	271	12	TGEV	TGEV	NNP
cord-341690-h8fqijk5	271	13	infection	infection	NN
cord-341690-h8fqijk5	271	14	(	(	-LRB-
cord-341690-h8fqijk5	271	15	for	for	IN
cord-341690-h8fqijk5	271	16	example	example	NN
cord-341690-h8fqijk5	271	17	,	,	,
cord-341690-h8fqijk5	271	18	the	the	DT
cord-341690-h8fqijk5	271	19	Ras	Ras	NNP
cord-341690-h8fqijk5	271	20	-	-	HYPH
cord-341690-h8fqijk5	271	21	mediated	mediate	VBN
cord-341690-h8fqijk5	271	22	activation	activation	NN
cord-341690-h8fqijk5	271	23	of	of	IN
cord-341690-h8fqijk5	271	24	the	the	DT
cord-341690-h8fqijk5	271	25	Raf/	Raf/	NNP
cord-341690-h8fqijk5	271	26	MEK	MEK	NNP
cord-341690-h8fqijk5	271	27	/	/	SYM
cord-341690-h8fqijk5	271	28	ERK	ERK	NNP
cord-341690-h8fqijk5	271	29	cascade	cascade	NN
cord-341690-h8fqijk5	271	30	)	)	-RRB-
cord-341690-h8fqijk5	271	31	.	.	.
cord-341690-h8fqijk5	272	1	MAPK	MAPK	NNP
cord-341690-h8fqijk5	272	2	pathways	pathway	NNS
cord-341690-h8fqijk5	272	3	can	can	MD
cord-341690-h8fqijk5	272	4	also	also	RB
cord-341690-h8fqijk5	272	5	be	be	VB
cord-341690-h8fqijk5	272	6	activated	activate	VBN
cord-341690-h8fqijk5	272	7	by	by	IN
cord-341690-h8fqijk5	272	8	the	the	DT
cord-341690-h8fqijk5	272	9	EGFR	EGFR	NNP
cord-341690-h8fqijk5	272	10	-	-	HYPH
cord-341690-h8fqijk5	272	11	PI3K	PI3K	NNP
cord-341690-h8fqijk5	272	12	-	-	HYPH
cord-341690-h8fqijk5	272	13	RhoGTPases	rhogtpase	NNS
cord-341690-h8fqijk5	272	14	signaling	signal	VBG
cord-341690-h8fqijk5	272	15	pathway	pathway	NN
cord-341690-h8fqijk5	272	16	[	[	-LRB-
cord-341690-h8fqijk5	272	17	43	43	CD
cord-341690-h8fqijk5	272	18	,	,	,
cord-341690-h8fqijk5	272	19	44	44	CD
cord-341690-h8fqijk5	272	20	]	]	-RRB-
cord-341690-h8fqijk5	272	21	.	.	.
cord-341690-h8fqijk5	273	1	These	these	DT
cord-341690-h8fqijk5	273	2	data	datum	NNS
cord-341690-h8fqijk5	273	3	demonstrate	demonstrate	VBP
cord-341690-h8fqijk5	273	4	that	that	IN
cord-341690-h8fqijk5	273	5	TGEV	TGEV	NNP
cord-341690-h8fqijk5	273	6	also	also	RB
cord-341690-h8fqijk5	273	7	activates	activate	VBZ
cord-341690-h8fqijk5	273	8	MAPK	MAPK	NNP
cord-341690-h8fqijk5	273	9	pathways	pathway	NNS
cord-341690-h8fqijk5	273	10	to	to	TO
cord-341690-h8fqijk5	273	11	regulate	regulate	VB
cord-341690-h8fqijk5	273	12	the	the	DT
cord-341690-h8fqijk5	273	13	actin	actin	NN
cord-341690-h8fqijk5	273	14	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	273	15	through	through	IN
cord-341690-h8fqijk5	273	16	EGFR	EGFR	NNP
cord-341690-h8fqijk5	273	17	early	early	RB
cord-341690-h8fqijk5	273	18	in	in	IN
cord-341690-h8fqijk5	273	19	infection	infection	NN
cord-341690-h8fqijk5	273	20	.	.	.
cord-341690-h8fqijk5	274	1	EGFR	EGFR	NNP
cord-341690-h8fqijk5	274	2	,	,	,
cord-341690-h8fqijk5	274	3	a	a	DT
cord-341690-h8fqijk5	274	4	member	member	NN
cord-341690-h8fqijk5	274	5	of	of	IN
cord-341690-h8fqijk5	274	6	the	the	DT
cord-341690-h8fqijk5	274	7	ErbB	ErbB	NNP
cord-341690-h8fqijk5	274	8	receptor	receptor	NN
cord-341690-h8fqijk5	274	9	family	family	NN
cord-341690-h8fqijk5	274	10	,	,	,
cord-341690-h8fqijk5	274	11	is	be	VBZ
cord-341690-h8fqijk5	274	12	expressed	express	VBN
cord-341690-h8fqijk5	274	13	in	in	IN
cord-341690-h8fqijk5	274	14	many	many	JJ
cord-341690-h8fqijk5	274	15	cell	cell	NN
cord-341690-h8fqijk5	274	16	types	type	NNS
cord-341690-h8fqijk5	274	17	.	.	.
cord-341690-h8fqijk5	275	1	The	the	DT
cord-341690-h8fqijk5	275	2	primary	primary	JJ
cord-341690-h8fqijk5	275	3	signaling	signal	VBG
cord-341690-h8fqijk5	275	4	pathways	pathway	NNS
cord-341690-h8fqijk5	275	5	activated	activate	VBN
cord-341690-h8fqijk5	275	6	by	by	IN
cord-341690-h8fqijk5	275	7	RTKs	rtk	NNS
cord-341690-h8fqijk5	275	8	include	include	VBP
cord-341690-h8fqijk5	275	9	PI3K	PI3K	NNP
cord-341690-h8fqijk5	275	10	/	/	SYM
cord-341690-h8fqijk5	275	11	Akt	Akt	NNP
cord-341690-h8fqijk5	275	12	,	,	,
cord-341690-h8fqijk5	275	13	Ras/	Ras/	NNP
cord-341690-h8fqijk5	275	14	www.impactjournals.com/oncotarget	www.impactjournals.com/oncotarget	NNP
cord-341690-h8fqijk5	276	1	Raf	Raf	NNP
cord-341690-h8fqijk5	276	2	/	/	SYM
cord-341690-h8fqijk5	276	3	ERK1/2	ERK1/2	NNP
cord-341690-h8fqijk5	276	4	,	,	,
cord-341690-h8fqijk5	276	5	and	and	CC
cord-341690-h8fqijk5	276	6	signal	signal	NN
cord-341690-h8fqijk5	276	7	transduction	transduction	NN
cord-341690-h8fqijk5	276	8	and	and	CC
cord-341690-h8fqijk5	276	9	activator	activator	NN
cord-341690-h8fqijk5	276	10	of	of	IN
cord-341690-h8fqijk5	276	11	transcription	transcription	NN
cord-341690-h8fqijk5	276	12	(	(	-LRB-
cord-341690-h8fqijk5	276	13	STAT	stat	NN
cord-341690-h8fqijk5	276	14	)	)	-RRB-
cord-341690-h8fqijk5	276	15	pathways	pathway	NNS
cord-341690-h8fqijk5	276	16	.	.	.
cord-341690-h8fqijk5	277	1	Our	-PRON-	PRP$
cord-341690-h8fqijk5	277	2	data	data	NN
cord-341690-h8fqijk5	277	3	provides	provide	VBZ
cord-341690-h8fqijk5	277	4	evidence	evidence	NN
cord-341690-h8fqijk5	277	5	that	that	IN
cord-341690-h8fqijk5	277	6	EGFR	EGFR	NNP
cord-341690-h8fqijk5	277	7	acts	act	VBZ
cord-341690-h8fqijk5	277	8	as	as	IN
cord-341690-h8fqijk5	277	9	a	a	DT
cord-341690-h8fqijk5	277	10	signaling	signal	VBG
cord-341690-h8fqijk5	277	11	-	-	HYPH
cord-341690-h8fqijk5	277	12	promoter	promoter	NN
cord-341690-h8fqijk5	277	13	that	that	WDT
cord-341690-h8fqijk5	277	14	is	be	VBZ
cord-341690-h8fqijk5	277	15	involved	involve	VBN
cord-341690-h8fqijk5	277	16	in	in	IN
cord-341690-h8fqijk5	277	17	the	the	DT
cord-341690-h8fqijk5	277	18	regulation	regulation	NN
cord-341690-h8fqijk5	277	19	of	of	IN
cord-341690-h8fqijk5	277	20	actin	actin	NN
cord-341690-h8fqijk5	277	21	and	and	CC
cord-341690-h8fqijk5	277	22	TGEV	TGEV	NNP
cord-341690-h8fqijk5	277	23	internalization	internalization	NN
cord-341690-h8fqijk5	277	24	.	.	.
cord-341690-h8fqijk5	278	1	Human	human	JJ
cord-341690-h8fqijk5	278	2	papillomavirus	papillomavirus	NN
cord-341690-h8fqijk5	278	3	(	(	-LRB-
cord-341690-h8fqijk5	278	4	HPV	hpv	NN
cord-341690-h8fqijk5	278	5	)	)	-RRB-
cord-341690-h8fqijk5	278	6	infection	infection	NN
cord-341690-h8fqijk5	278	7	induces	induce	VBZ
cord-341690-h8fqijk5	278	8	filopodia	filopodia	NNS
cord-341690-h8fqijk5	278	9	formation	formation	NN
cord-341690-h8fqijk5	278	10	and	and	CC
cord-341690-h8fqijk5	278	11	the	the	DT
cord-341690-h8fqijk5	278	12	dissolution	dissolution	NN
cord-341690-h8fqijk5	278	13	of	of	IN
cord-341690-h8fqijk5	278	14	stress	stress	NN
cord-341690-h8fqijk5	278	15	fibers	fiber	NNS
cord-341690-h8fqijk5	278	16	by	by	IN
cord-341690-h8fqijk5	278	17	10	10	CD
cord-341690-h8fqijk5	278	18	mpi	mpi	NN
cord-341690-h8fqijk5	278	19	,	,	,
cord-341690-h8fqijk5	278	20	and	and	CC
cord-341690-h8fqijk5	278	21	HPV	HPV	NNP
cord-341690-h8fqijk5	278	22	entry	entry	NN
cord-341690-h8fqijk5	278	23	is	be	VBZ
cord-341690-h8fqijk5	278	24	also	also	RB
cord-341690-h8fqijk5	278	25	blocked	block	VBN
cord-341690-h8fqijk5	278	26	by	by	IN
cord-341690-h8fqijk5	278	27	RTK	RTK	NNP
cord-341690-h8fqijk5	278	28	and	and	CC
cord-341690-h8fqijk5	278	29	PI3	PI3	NNP
cord-341690-h8fqijk5	278	30	K	K	NNP
cord-341690-h8fqijk5	278	31	inhibitors	inhibitor	NNS
cord-341690-h8fqijk5	278	32	[	[	-LRB-
cord-341690-h8fqijk5	278	33	45	45	CD
cord-341690-h8fqijk5	278	34	]	]	-RRB-
cord-341690-h8fqijk5	278	35	.	.	.
cord-341690-h8fqijk5	279	1	We	-PRON-	PRP
cord-341690-h8fqijk5	279	2	find	find	VBP
cord-341690-h8fqijk5	279	3	that	that	IN
cord-341690-h8fqijk5	279	4	the	the	DT
cord-341690-h8fqijk5	279	5	EGFR	EGFR	NNP
cord-341690-h8fqijk5	279	6	specific	specific	JJ
cord-341690-h8fqijk5	279	7	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	279	8	AG1478	ag1478	NN
cord-341690-h8fqijk5	279	9	and	and	CC
cord-341690-h8fqijk5	279	10	PI3	PI3	NNP
cord-341690-h8fqijk5	279	11	K	K	NNP
cord-341690-h8fqijk5	279	12	specific	specific	JJ
cord-341690-h8fqijk5	279	13	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	279	14	Y27632	Y27632	NNP
cord-341690-h8fqijk5	279	15	block	block	NN
cord-341690-h8fqijk5	279	16	stress	stress	NN
cord-341690-h8fqijk5	279	17	fiber	fiber	NN
cord-341690-h8fqijk5	279	18	dissolution	dissolution	NN
cord-341690-h8fqijk5	279	19	,	,	,
cord-341690-h8fqijk5	279	20	suggesting	suggest	VBG
cord-341690-h8fqijk5	279	21	that	that	IN
cord-341690-h8fqijk5	279	22	the	the	DT
cord-341690-h8fqijk5	279	23	EGFR	EGFR	NNP
cord-341690-h8fqijk5	279	24	and	and	CC
cord-341690-h8fqijk5	279	25	PI3	PI3	NNP
cord-341690-h8fqijk5	279	26	K	K	NNP
cord-341690-h8fqijk5	279	27	are	be	VBP
cord-341690-h8fqijk5	279	28	involved	involve	VBN
cord-341690-h8fqijk5	279	29	in	in	IN
cord-341690-h8fqijk5	279	30	the	the	DT
cord-341690-h8fqijk5	279	31	signaling	signal	VBG
cord-341690-h8fqijk5	279	32	pathway	pathway	NN
cord-341690-h8fqijk5	279	33	that	that	WDT
cord-341690-h8fqijk5	279	34	regulates	regulate	VBZ
cord-341690-h8fqijk5	279	35	the	the	DT
cord-341690-h8fqijk5	279	36	assembly	assembly	NN
cord-341690-h8fqijk5	279	37	of	of	IN
cord-341690-h8fqijk5	279	38	F	F	NNP
cord-341690-h8fqijk5	279	39	-	-	HYPH
cord-341690-h8fqijk5	279	40	actin	actin	NNP
cord-341690-h8fqijk5	279	41	.	.	.
cord-341690-h8fqijk5	280	1	Our	-PRON-	PRP$
cord-341690-h8fqijk5	280	2	results	result	NNS
cord-341690-h8fqijk5	280	3	indicate	indicate	VBP
cord-341690-h8fqijk5	280	4	that	that	IN
cord-341690-h8fqijk5	280	5	EGFR	EGFR	NNP
cord-341690-h8fqijk5	280	6	is	be	VBZ
cord-341690-h8fqijk5	280	7	activated	activate	VBN
cord-341690-h8fqijk5	280	8	by	by	IN
cord-341690-h8fqijk5	280	9	TGEV	TGEV	NNS
cord-341690-h8fqijk5	280	10	binding	bind	VBG
cord-341690-h8fqijk5	280	11	and	and	CC
cord-341690-h8fqijk5	280	12	promotes	promote	VBZ
cord-341690-h8fqijk5	280	13	TGEV	TGEV	NNP
cord-341690-h8fqijk5	280	14	uptake	uptake	NN
cord-341690-h8fqijk5	280	15	into	into	IN
cord-341690-h8fqijk5	280	16	host	host	NN
cord-341690-h8fqijk5	280	17	cells	cell	NNS
cord-341690-h8fqijk5	280	18	.	.	.
cord-341690-h8fqijk5	281	1	It	-PRON-	PRP
cord-341690-h8fqijk5	281	2	has	have	VBZ
cord-341690-h8fqijk5	281	3	been	be	VBN
cord-341690-h8fqijk5	281	4	reported	report	VBN
cord-341690-h8fqijk5	281	5	that	that	IN
cord-341690-h8fqijk5	281	6	a	a	DT
cord-341690-h8fqijk5	281	7	200-kDa	200-kda	CD
cord-341690-h8fqijk5	281	8	protein	protein	NN
cord-341690-h8fqijk5	281	9	in	in	IN
cord-341690-h8fqijk5	281	10	ST	ST	NNP
cord-341690-h8fqijk5	281	11	cells	cell	NNS
cord-341690-h8fqijk5	281	12	and	and	CC
cord-341690-h8fqijk5	281	13	in	in	IN
cord-341690-h8fqijk5	281	14	villous	villous	NNP
cord-341690-h8fqijk5	281	15	enterocytes	enterocytes	NNP
cord-341690-h8fqijk5	281	16	in	in	IN
cord-341690-h8fqijk5	281	17	newborn	newborn	JJ
cord-341690-h8fqijk5	281	18	pigs	pig	NNS
cord-341690-h8fqijk5	281	19	may	may	MD
cord-341690-h8fqijk5	281	20	be	be	VB
cord-341690-h8fqijk5	281	21	a	a	DT
cord-341690-h8fqijk5	281	22	second	second	JJ
cord-341690-h8fqijk5	281	23	receptor	receptor	NN
cord-341690-h8fqijk5	281	24	for	for	IN
cord-341690-h8fqijk5	281	25	TGEV	TGEV	NNP
cord-341690-h8fqijk5	281	26	and	and	CC
cord-341690-h8fqijk5	281	27	contribute	contribute	VB
cord-341690-h8fqijk5	281	28	to	to	IN
cord-341690-h8fqijk5	281	29	the	the	DT
cord-341690-h8fqijk5	281	30	age	age	NN
cord-341690-h8fqijk5	281	31	sensitivity	sensitivity	NN
cord-341690-h8fqijk5	281	32	of	of	IN
cord-341690-h8fqijk5	281	33	these	these	DT
cord-341690-h8fqijk5	281	34	animals	animal	NNS
cord-341690-h8fqijk5	281	35	to	to	IN
cord-341690-h8fqijk5	281	36	the	the	DT
cord-341690-h8fqijk5	281	37	virus	virus	NN
cord-341690-h8fqijk5	281	38	[	[	-LRB-
cord-341690-h8fqijk5	281	39	46	46	CD
cord-341690-h8fqijk5	281	40	]	]	-RRB-
cord-341690-h8fqijk5	281	41	,	,	,
cord-341690-h8fqijk5	281	42	but	but	CC
cord-341690-h8fqijk5	281	43	the	the	DT
cord-341690-h8fqijk5	281	44	identity	identity	NN
cord-341690-h8fqijk5	281	45	of	of	IN
cord-341690-h8fqijk5	281	46	this	this	DT
cord-341690-h8fqijk5	281	47	200-kDa	200-kda	CD
cord-341690-h8fqijk5	281	48	receptor	receptor	NN
cord-341690-h8fqijk5	281	49	has	have	VBZ
cord-341690-h8fqijk5	281	50	not	not	RB
cord-341690-h8fqijk5	281	51	been	be	VBN
cord-341690-h8fqijk5	281	52	determined	determine	VBN
cord-341690-h8fqijk5	281	53	.	.	.
cord-341690-h8fqijk5	282	1	Although	although	IN
cord-341690-h8fqijk5	282	2	EGFR	EGFR	NNP
cord-341690-h8fqijk5	282	3	is	be	VBZ
cord-341690-h8fqijk5	282	4	a	a	DT
cord-341690-h8fqijk5	282	5	170-kDa	170-kda	JJ
cord-341690-h8fqijk5	282	6	transmembrane	transmembrane	NN
cord-341690-h8fqijk5	282	7	protein	protein	NN
cord-341690-h8fqijk5	282	8	,	,	,
cord-341690-h8fqijk5	282	9	we	-PRON-	PRP
cord-341690-h8fqijk5	282	10	have	have	VBP
cord-341690-h8fqijk5	282	11	found	find	VBN
cord-341690-h8fqijk5	282	12	that	that	IN
cord-341690-h8fqijk5	282	13	it	-PRON-	PRP
cord-341690-h8fqijk5	282	14	interacted	interact	VBD
cord-341690-h8fqijk5	282	15	with	with	IN
cord-341690-h8fqijk5	282	16	TGEV	TGEV	NNP
cord-341690-h8fqijk5	282	17	S1	S1	NNP
cord-341690-h8fqijk5	282	18	protein	protein	NN
cord-341690-h8fqijk5	282	19	,	,	,
cord-341690-h8fqijk5	282	20	and	and	CC
cord-341690-h8fqijk5	282	21	therefore	therefore	RB
cord-341690-h8fqijk5	282	22	should	should	MD
cord-341690-h8fqijk5	282	23	be	be	VB
cord-341690-h8fqijk5	282	24	considered	consider	VBN
cord-341690-h8fqijk5	282	25	as	as	IN
cord-341690-h8fqijk5	282	26	a	a	DT
cord-341690-h8fqijk5	282	27	factor	factor	NN
cord-341690-h8fqijk5	282	28	in	in	IN
cord-341690-h8fqijk5	282	29	determining	determine	VBG
cord-341690-h8fqijk5	282	30	the	the	DT
cord-341690-h8fqijk5	282	31	high	high	JJ
cord-341690-h8fqijk5	282	32	level	level	NN
cord-341690-h8fqijk5	282	33	of	of	IN
cord-341690-h8fqijk5	282	34	susceptibility	susceptibility	NN
cord-341690-h8fqijk5	282	35	of	of	IN
cord-341690-h8fqijk5	282	36	newborn	newborn	JJ
cord-341690-h8fqijk5	282	37	pigs	pig	NNS
cord-341690-h8fqijk5	282	38	to	to	IN
cord-341690-h8fqijk5	282	39	TGEV	TGEV	NNP
cord-341690-h8fqijk5	282	40	.	.	.
cord-341690-h8fqijk5	283	1	The	the	DT
cord-341690-h8fqijk5	283	2	clustering	clustering	NN
cord-341690-h8fqijk5	283	3	of	of	IN
cord-341690-h8fqijk5	283	4	large	large	JJ
cord-341690-h8fqijk5	283	5	lipid	lipid	NN
cord-341690-h8fqijk5	283	6	rafts	raft	NNS
cord-341690-h8fqijk5	283	7	is	be	VBZ
cord-341690-h8fqijk5	283	8	caused	cause	VBN
cord-341690-h8fqijk5	283	9	by	by	IN
cord-341690-h8fqijk5	283	10	protein	protein	NN
cord-341690-h8fqijk5	283	11	modifications	modification	NNS
cord-341690-h8fqijk5	283	12	such	such	JJ
cord-341690-h8fqijk5	283	13	as	as	IN
cord-341690-h8fqijk5	283	14	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	283	15	,	,	,
cord-341690-h8fqijk5	283	16	which	which	WDT
cord-341690-h8fqijk5	283	17	increase	increase	VBP
cord-341690-h8fqijk5	283	18	the	the	DT
cord-341690-h8fqijk5	283	19	number	number	NN
cord-341690-h8fqijk5	283	20	of	of	IN
cord-341690-h8fqijk5	283	21	protein	protein	NN
cord-341690-h8fqijk5	283	22	-	-	HYPH
cord-341690-h8fqijk5	283	23	protein	protein	NN
cord-341690-h8fqijk5	283	24	interactions	interaction	NNS
cord-341690-h8fqijk5	283	25	[	[	-LRB-
cord-341690-h8fqijk5	283	26	47	47	CD
cord-341690-h8fqijk5	283	27	]	]	-RRB-
cord-341690-h8fqijk5	283	28	.	.	.
cord-341690-h8fqijk5	284	1	We	-PRON-	PRP
cord-341690-h8fqijk5	284	2	found	find	VBD
cord-341690-h8fqijk5	284	3	that	that	IN
cord-341690-h8fqijk5	284	4	TGEV	TGEV	NNP
cord-341690-h8fqijk5	284	5	stimulated	stimulate	VBD
cord-341690-h8fqijk5	284	6	the	the	DT
cord-341690-h8fqijk5	284	7	clustering	clustering	NN
cord-341690-h8fqijk5	284	8	of	of	IN
cord-341690-h8fqijk5	284	9	large	large	JJ
cord-341690-h8fqijk5	284	10	lipid	lipid	NN
cord-341690-h8fqijk5	284	11	rafts	raft	NNS
cord-341690-h8fqijk5	284	12	,	,	,
cord-341690-h8fqijk5	284	13	and	and	CC
cord-341690-h8fqijk5	284	14	that	that	DT
cord-341690-h8fqijk5	284	15	activated	activate	VBN
cord-341690-h8fqijk5	284	16	EGFR	EGFR	NNP
cord-341690-h8fqijk5	284	17	,	,	,
cord-341690-h8fqijk5	284	18	and	and	CC
cord-341690-h8fqijk5	284	19	TGEV	TGEV	NNP
cord-341690-h8fqijk5	284	20	virions	virion	NNS
cord-341690-h8fqijk5	284	21	were	be	VBD
cord-341690-h8fqijk5	284	22	associated	associate	VBN
cord-341690-h8fqijk5	284	23	with	with	IN
cord-341690-h8fqijk5	284	24	the	the	DT
cord-341690-h8fqijk5	284	25	rafts	raft	NNS
cord-341690-h8fqijk5	284	26	.	.	.
cord-341690-h8fqijk5	285	1	The	the	DT
cord-341690-h8fqijk5	285	2	clustering	clustering	NN
cord-341690-h8fqijk5	285	3	of	of	IN
cord-341690-h8fqijk5	285	4	the	the	DT
cord-341690-h8fqijk5	285	5	lipid	lipid	NN
cord-341690-h8fqijk5	285	6	rafts	raft	NNS
cord-341690-h8fqijk5	285	7	functions	function	NNS
cord-341690-h8fqijk5	285	8	as	as	IN
cord-341690-h8fqijk5	285	9	a	a	DT
cord-341690-h8fqijk5	285	10	signaling	signal	VBG
cord-341690-h8fqijk5	285	11	platform	platform	NN
cord-341690-h8fqijk5	285	12	,	,	,
cord-341690-h8fqijk5	285	13	but	but	CC
cord-341690-h8fqijk5	285	14	the	the	DT
cord-341690-h8fqijk5	285	15	activation	activation	NN
cord-341690-h8fqijk5	285	16	of	of	IN
cord-341690-h8fqijk5	285	17	downstream	downstream	JJ
cord-341690-h8fqijk5	285	18	signaling	signal	VBG
cord-341690-h8fqijk5	285	19	pathways	pathway	NNS
cord-341690-h8fqijk5	285	20	were	be	VBD
cord-341690-h8fqijk5	285	21	inhibited	inhibit	VBN
cord-341690-h8fqijk5	285	22	by	by	IN
cord-341690-h8fqijk5	285	23	agents	agent	NNS
cord-341690-h8fqijk5	285	24	that	that	WDT
cord-341690-h8fqijk5	285	25	remove	remove	VBP
cord-341690-h8fqijk5	285	26	the	the	DT
cord-341690-h8fqijk5	285	27	rafts	raft	NNS
cord-341690-h8fqijk5	285	28	.	.	.
cord-341690-h8fqijk5	286	1	The	the	DT
cord-341690-h8fqijk5	286	2	integrity	integrity	NN
cord-341690-h8fqijk5	286	3	of	of	IN
cord-341690-h8fqijk5	286	4	lipid	lipid	NN
cord-341690-h8fqijk5	286	5	rafts	raft	NNS
cord-341690-h8fqijk5	286	6	is	be	VBZ
cord-341690-h8fqijk5	286	7	essential	essential	JJ
cord-341690-h8fqijk5	286	8	for	for	IN
cord-341690-h8fqijk5	286	9	the	the	DT
cord-341690-h8fqijk5	286	10	activation	activation	NN
cord-341690-h8fqijk5	286	11	of	of	IN
cord-341690-h8fqijk5	286	12	Src	Src	NNP
cord-341690-h8fqijk5	286	13	kinase	kinase	NN
cord-341690-h8fqijk5	286	14	and	and	CC
cord-341690-h8fqijk5	286	15	the	the	DT
cord-341690-h8fqijk5	286	16	PI3K/	PI3K/	NNP
cord-341690-h8fqijk5	286	17	Akt	Akt	NNP
cord-341690-h8fqijk5	286	18	pathway	pathway	NN
cord-341690-h8fqijk5	286	19	[	[	-LRB-
cord-341690-h8fqijk5	286	20	48	48	CD
cord-341690-h8fqijk5	286	21	]	]	-RRB-
cord-341690-h8fqijk5	286	22	.	.	.
cord-341690-h8fqijk5	287	1	Based	base	VBN
cord-341690-h8fqijk5	287	2	on	on	IN
cord-341690-h8fqijk5	287	3	these	these	DT
cord-341690-h8fqijk5	287	4	data	datum	NNS
cord-341690-h8fqijk5	287	5	and	and	CC
cord-341690-h8fqijk5	287	6	our	-PRON-	PRP$
cord-341690-h8fqijk5	287	7	results	result	NNS
cord-341690-h8fqijk5	287	8	,	,	,
cord-341690-h8fqijk5	287	9	we	-PRON-	PRP
cord-341690-h8fqijk5	287	10	hypothesize	hypothesize	VBP
cord-341690-h8fqijk5	287	11	that	that	IN
cord-341690-h8fqijk5	287	12	TGEV	TGEV	NNP
cord-341690-h8fqijk5	287	13	induces	induce	VBZ
cord-341690-h8fqijk5	287	14	the	the	DT
cord-341690-h8fqijk5	287	15	clustering	clustering	NN
cord-341690-h8fqijk5	287	16	of	of	IN
cord-341690-h8fqijk5	287	17	lipid	lipid	NN
cord-341690-h8fqijk5	287	18	rafts	raft	NNS
cord-341690-h8fqijk5	287	19	by	by	IN
cord-341690-h8fqijk5	287	20	the	the	DT
cord-341690-h8fqijk5	287	21	binding	binding	NN
cord-341690-h8fqijk5	287	22	of	of	IN
cord-341690-h8fqijk5	287	23	spike	spike	NN
cord-341690-h8fqijk5	287	24	protein	protein	NN
cord-341690-h8fqijk5	287	25	to	to	IN
cord-341690-h8fqijk5	287	26	APN	APN	NNP
cord-341690-h8fqijk5	287	27	and	and	CC
cord-341690-h8fqijk5	287	28	EGFR	EGFR	NNP
cord-341690-h8fqijk5	287	29	.	.	.
cord-341690-h8fqijk5	288	1	The	the	DT
cord-341690-h8fqijk5	288	2	activated	activate	VBN
cord-341690-h8fqijk5	288	3	EGFR	EGFR	NNP
cord-341690-h8fqijk5	288	4	then	then	RB
cord-341690-h8fqijk5	288	5	transfers	transfer	VBZ
cord-341690-h8fqijk5	288	6	the	the	DT
cord-341690-h8fqijk5	288	7	signal	signal	NN
cord-341690-h8fqijk5	288	8	to	to	TO
cord-341690-h8fqijk5	288	9	effector	effector	VB
cord-341690-h8fqijk5	288	10	proteins	protein	NNS
cord-341690-h8fqijk5	288	11	downstream	downstream	RB
cord-341690-h8fqijk5	288	12	.	.	.
cord-341690-h8fqijk5	289	1	APN	APN	NNP
cord-341690-h8fqijk5	289	2	is	be	VBZ
cord-341690-h8fqijk5	289	3	the	the	DT
cord-341690-h8fqijk5	289	4	specific	specific	JJ
cord-341690-h8fqijk5	289	5	receptor	receptor	NN
cord-341690-h8fqijk5	289	6	for	for	IN
cord-341690-h8fqijk5	289	7	TGEV	TGEV	NNP
cord-341690-h8fqijk5	289	8	.	.	.
cord-341690-h8fqijk5	290	1	Our	-PRON-	PRP$
cord-341690-h8fqijk5	290	2	experiments	experiment	NNS
cord-341690-h8fqijk5	290	3	identified	identify	VBD
cord-341690-h8fqijk5	290	4	EGFR	EGFR	NNP
cord-341690-h8fqijk5	290	5	as	as	IN
cord-341690-h8fqijk5	290	6	another	another	DT
cord-341690-h8fqijk5	290	7	promoter	promoter	NN
cord-341690-h8fqijk5	290	8	for	for	IN
cord-341690-h8fqijk5	290	9	TGEV	TGEV	NNP
cord-341690-h8fqijk5	290	10	entry	entry	NN
cord-341690-h8fqijk5	290	11	.	.	.
cord-341690-h8fqijk5	291	1	It	-PRON-	PRP
cord-341690-h8fqijk5	291	2	is	be	VBZ
cord-341690-h8fqijk5	291	3	not	not	RB
cord-341690-h8fqijk5	291	4	known	know	VBN
cord-341690-h8fqijk5	291	5	whether	whether	IN
cord-341690-h8fqijk5	291	6	APN	APN	NNP
cord-341690-h8fqijk5	291	7	and	and	CC
cord-341690-h8fqijk5	291	8	EGFR	EGFR	NNP
cord-341690-h8fqijk5	291	9	are	be	VBP
cord-341690-h8fqijk5	291	10	related	relate	VBN
cord-341690-h8fqijk5	291	11	in	in	IN
cord-341690-h8fqijk5	291	12	any	any	DT
cord-341690-h8fqijk5	291	13	way	way	NN
cord-341690-h8fqijk5	291	14	,	,	,
cord-341690-h8fqijk5	291	15	or	or	CC
cord-341690-h8fqijk5	291	16	whether	whether	IN
cord-341690-h8fqijk5	291	17	other	other	JJ
cord-341690-h8fqijk5	291	18	TGEV	TGEV	NNP
cord-341690-h8fqijk5	291	19	receptors	receptor	NNS
cord-341690-h8fqijk5	291	20	exist	exist	VBP
cord-341690-h8fqijk5	291	21	.	.	.
cord-341690-h8fqijk5	292	1	Actin	actin	NN
cord-341690-h8fqijk5	292	2	plays	play	VBZ
cord-341690-h8fqijk5	292	3	an	an	DT
cord-341690-h8fqijk5	292	4	important	important	JJ
cord-341690-h8fqijk5	292	5	role	role	NN
cord-341690-h8fqijk5	292	6	in	in	IN
cord-341690-h8fqijk5	292	7	the	the	DT
cord-341690-h8fqijk5	292	8	endocytosis	endocytosis	NN
cord-341690-h8fqijk5	292	9	and	and	CC
cord-341690-h8fqijk5	292	10	vesicle	vesicle	NN
cord-341690-h8fqijk5	292	11	transport	transport	NN
cord-341690-h8fqijk5	292	12	[	[	-LRB-
cord-341690-h8fqijk5	292	13	49	49	CD
cord-341690-h8fqijk5	292	14	]	]	-RRB-
cord-341690-h8fqijk5	292	15	,	,	,
cord-341690-h8fqijk5	292	16	and	and	CC
cord-341690-h8fqijk5	292	17	the	the	DT
cord-341690-h8fqijk5	292	18	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	292	19	is	be	VBZ
cord-341690-h8fqijk5	292	20	involved	involve	VBN
cord-341690-h8fqijk5	292	21	in	in	IN
cord-341690-h8fqijk5	292	22	different	different	JJ
cord-341690-h8fqijk5	292	23	stages	stage	NNS
cord-341690-h8fqijk5	292	24	of	of	IN
cord-341690-h8fqijk5	292	25	both	both	DT
cord-341690-h8fqijk5	292	26	clathrin	clathrin	NN
cord-341690-h8fqijk5	292	27	-	-	HYPH
cord-341690-h8fqijk5	292	28	and	and	CC
cord-341690-h8fqijk5	292	29	caveola	caveola	NN
cord-341690-h8fqijk5	292	30	-	-	HYPH
cord-341690-h8fqijk5	292	31	mediated	mediate	VBN
cord-341690-h8fqijk5	292	32	endocytosis	endocytosis	NN
cord-341690-h8fqijk5	292	33	.	.	.
cord-341690-h8fqijk5	293	1	Understanding	understand	VBG
cord-341690-h8fqijk5	293	2	the	the	DT
cord-341690-h8fqijk5	293	3	main	main	JJ
cord-341690-h8fqijk5	293	4	endocytic	endocytic	JJ
cord-341690-h8fqijk5	293	5	pathway	pathway	NN
cord-341690-h8fqijk5	293	6	of	of	IN
cord-341690-h8fqijk5	293	7	TGEV	TGEV	NNP
cord-341690-h8fqijk5	293	8	,	,	,
cord-341690-h8fqijk5	293	9	and	and	CC
cord-341690-h8fqijk5	293	10	the	the	DT
cord-341690-h8fqijk5	293	11	molecular	molecular	JJ
cord-341690-h8fqijk5	293	12	mechanisms	mechanism	NNS
cord-341690-h8fqijk5	293	13	regulating	regulate	VBG
cord-341690-h8fqijk5	293	14	this	this	DT
cord-341690-h8fqijk5	293	15	process	process	NN
cord-341690-h8fqijk5	293	16	,	,	,
cord-341690-h8fqijk5	293	17	will	will	MD
cord-341690-h8fqijk5	293	18	require	require	VB
cord-341690-h8fqijk5	293	19	further	further	JJ
cord-341690-h8fqijk5	293	20	investigation	investigation	NN
cord-341690-h8fqijk5	293	21	.	.	.
cord-341690-h8fqijk5	294	1	These	these	DT
cord-341690-h8fqijk5	294	2	findings	finding	NNS
cord-341690-h8fqijk5	294	3	are	be	VBP
cord-341690-h8fqijk5	294	4	conducive	conducive	JJ
cord-341690-h8fqijk5	294	5	to	to	IN
cord-341690-h8fqijk5	294	6	enhancing	enhance	VBG
cord-341690-h8fqijk5	294	7	our	-PRON-	PRP$
cord-341690-h8fqijk5	294	8	understanding	understanding	NN
cord-341690-h8fqijk5	294	9	of	of	IN
cord-341690-h8fqijk5	294	10	the	the	DT
cord-341690-h8fqijk5	294	11	entry	entry	NN
cord-341690-h8fqijk5	294	12	mechanism	mechanism	NN
cord-341690-h8fqijk5	294	13	of	of	IN
cord-341690-h8fqijk5	294	14	TGEV	TGEV	NNP
cord-341690-h8fqijk5	294	15	and	and	CC
cord-341690-h8fqijk5	294	16	providing	provide	VBG
cord-341690-h8fqijk5	294	17	a	a	DT
cord-341690-h8fqijk5	294	18	potential	potential	JJ
cord-341690-h8fqijk5	294	19	target	target	NN
cord-341690-h8fqijk5	294	20	for	for	IN
cord-341690-h8fqijk5	294	21	the	the	DT
cord-341690-h8fqijk5	294	22	development	development	NN
cord-341690-h8fqijk5	294	23	of	of	IN
cord-341690-h8fqijk5	294	24	new	new	JJ
cord-341690-h8fqijk5	294	25	anti	anti	JJ
cord-341690-h8fqijk5	294	26	-	-	JJ
cord-341690-h8fqijk5	294	27	TGEV	tgev	JJ
cord-341690-h8fqijk5	294	28	therapies	therapy	NNS
cord-341690-h8fqijk5	294	29	.	.	.
cord-341690-h8fqijk5	295	1	IPEC	IPEC	NNP
cord-341690-h8fqijk5	295	2	-	-	HYPH
cord-341690-h8fqijk5	295	3	J2	j2	NN
cord-341690-h8fqijk5	295	4	cells	cell	NNS
cord-341690-h8fqijk5	295	5	are	be	VBP
cord-341690-h8fqijk5	295	6	porcine	porcine	JJ
cord-341690-h8fqijk5	295	7	intestinal	intestinal	JJ
cord-341690-h8fqijk5	295	8	columnar	columnar	JJ
cord-341690-h8fqijk5	295	9	epithelial	epithelial	JJ
cord-341690-h8fqijk5	295	10	cells	cell	NNS
cord-341690-h8fqijk5	295	11	that	that	WDT
cord-341690-h8fqijk5	295	12	were	be	VBD
cord-341690-h8fqijk5	295	13	isolated	isolate	VBN
cord-341690-h8fqijk5	295	14	from	from	IN
cord-341690-h8fqijk5	295	15	the	the	DT
cord-341690-h8fqijk5	295	16	middle	middle	JJ
cord-341690-h8fqijk5	295	17	jejunum	jejunum	NNS
cord-341690-h8fqijk5	295	18	of	of	IN
cord-341690-h8fqijk5	295	19	neonatal	neonatal	JJ
cord-341690-h8fqijk5	295	20	piglets	piglet	NNS
cord-341690-h8fqijk5	295	21	.	.	.
cord-341690-h8fqijk5	296	1	IPEC	IPEC	NNP
cord-341690-h8fqijk5	296	2	-	-	HYPH
cord-341690-h8fqijk5	296	3	J2	j2	NN
cord-341690-h8fqijk5	296	4	cells	cell	NNS
cord-341690-h8fqijk5	296	5	were	be	VBD
cord-341690-h8fqijk5	296	6	purchased	purchase	VBN
cord-341690-h8fqijk5	296	7	from	from	IN
cord-341690-h8fqijk5	296	8	DSMZ	DSMZ	NNP
cord-341690-h8fqijk5	296	9	(	(	-LRB-
cord-341690-h8fqijk5	296	10	Germany	Germany	NNP
cord-341690-h8fqijk5	296	11	)	)	-RRB-
cord-341690-h8fqijk5	296	12	.	.	.
cord-341690-h8fqijk5	297	1	HEK293	HEK293	NNP
cord-341690-h8fqijk5	297	2	T	t	NN
cord-341690-h8fqijk5	297	3	cells	cell	NNS
cord-341690-h8fqijk5	297	4	were	be	VBD
cord-341690-h8fqijk5	297	5	purchased	purchase	VBN
cord-341690-h8fqijk5	297	6	from	from	IN
cord-341690-h8fqijk5	297	7	ATCC	ATCC	NNP
cord-341690-h8fqijk5	297	8	(	(	-LRB-
cord-341690-h8fqijk5	297	9	United	United	NNP
cord-341690-h8fqijk5	297	10	States	States	NNP
cord-341690-h8fqijk5	297	11	)	)	-RRB-
cord-341690-h8fqijk5	297	12	.	.	.
cord-341690-h8fqijk5	298	1	Both	both	DT
cord-341690-h8fqijk5	298	2	IPEC	IPEC	NNP
cord-341690-h8fqijk5	298	3	-	-	HYPH
cord-341690-h8fqijk5	298	4	J2	J2	NNP
cord-341690-h8fqijk5	298	5	and	and	CC
cord-341690-h8fqijk5	298	6	HEK293	HEK293	NNP
cord-341690-h8fqijk5	298	7	T	t	NN
cord-341690-h8fqijk5	298	8	cells	cell	NNS
cord-341690-h8fqijk5	298	9	were	be	VBD
cord-341690-h8fqijk5	298	10	maintained	maintain	VBN
cord-341690-h8fqijk5	298	11	in	in	IN
cord-341690-h8fqijk5	298	12	Dulbecco	Dulbecco	NNP
cord-341690-h8fqijk5	298	13	's	's	POS
cord-341690-h8fqijk5	298	14	Modified	modify	VBN
cord-341690-h8fqijk5	298	15	Eagle	Eagle	NNP
cord-341690-h8fqijk5	298	16	's	's	POS
cord-341690-h8fqijk5	298	17	Medium	Medium	NNP
cord-341690-h8fqijk5	298	18	(	(	-LRB-
cord-341690-h8fqijk5	298	19	DMEM	DMEM	NNP
cord-341690-h8fqijk5	298	20	)	)	-RRB-
cord-341690-h8fqijk5	298	21	with	with	IN
cord-341690-h8fqijk5	298	22	high	high	JJ
cord-341690-h8fqijk5	298	23	glucose	glucose	NN
cord-341690-h8fqijk5	298	24	,	,	,
cord-341690-h8fqijk5	298	25	HEPES	HEPES	NNP
cord-341690-h8fqijk5	298	26	supplemented	supplement	VBD
cord-341690-h8fqijk5	298	27	with	with	IN
cord-341690-h8fqijk5	298	28	10	10	CD
cord-341690-h8fqijk5	298	29	%	%	NN
cord-341690-h8fqijk5	298	30	fetal	fetal	JJ
cord-341690-h8fqijk5	298	31	bovine	bovine	JJ
cord-341690-h8fqijk5	298	32	serum	serum	NN
cord-341690-h8fqijk5	298	33	(	(	-LRB-
cord-341690-h8fqijk5	298	34	FBS	FBS	NNP
cord-341690-h8fqijk5	298	35	,	,	,
cord-341690-h8fqijk5	298	36	GIBCO	GIBCO	NNP
cord-341690-h8fqijk5	298	37	)	)	-RRB-
cord-341690-h8fqijk5	298	38	,	,	,
cord-341690-h8fqijk5	298	39	1	1	CD
cord-341690-h8fqijk5	298	40	%	%	NN
cord-341690-h8fqijk5	298	41	penicillinstreptomycin	penicillinstreptomycin	NNS
cord-341690-h8fqijk5	298	42	(	(	-LRB-
cord-341690-h8fqijk5	298	43	Invitrogen	Invitrogen	NNP
cord-341690-h8fqijk5	298	44	)	)	-RRB-
cord-341690-h8fqijk5	298	45	at	at	IN
cord-341690-h8fqijk5	298	46	37	37	CD
cord-341690-h8fqijk5	298	47	°	°	NN
cord-341690-h8fqijk5	298	48	C	c	NN
cord-341690-h8fqijk5	298	49	in	in	IN
cord-341690-h8fqijk5	298	50	a	a	DT
cord-341690-h8fqijk5	298	51	5	5	CD
cord-341690-h8fqijk5	298	52	%	%	NN
cord-341690-h8fqijk5	298	53	CO	co	NN
cord-341690-h8fqijk5	298	54	2	2	CD
cord-341690-h8fqijk5	298	55	incubator	incubator	NN
cord-341690-h8fqijk5	298	56	(	(	-LRB-
cord-341690-h8fqijk5	298	57	Thermo	Thermo	NNP
cord-341690-h8fqijk5	298	58	Scientific	Scientific	NNP
cord-341690-h8fqijk5	298	59	)	)	-RRB-
cord-341690-h8fqijk5	298	60	.	.	.
cord-341690-h8fqijk5	299	1	Transmissible	transmissible	JJ
cord-341690-h8fqijk5	299	2	gastroenteritis	gastroenteritis	NN
cord-341690-h8fqijk5	299	3	virus	virus	NN
cord-341690-h8fqijk5	299	4	(	(	-LRB-
cord-341690-h8fqijk5	299	5	strain	strain	NN
cord-341690-h8fqijk5	299	6	SHXB	SHXB	NNP
cord-341690-h8fqijk5	299	7	)	)	-RRB-
cord-341690-h8fqijk5	299	8	was	be	VBD
cord-341690-h8fqijk5	299	9	isolated	isolate	VBN
cord-341690-h8fqijk5	299	10	in	in	IN
cord-341690-h8fqijk5	299	11	Shanghai	Shanghai	NNP
cord-341690-h8fqijk5	299	12	,	,	,
cord-341690-h8fqijk5	299	13	China	China	NNP
cord-341690-h8fqijk5	299	14	.	.	.
cord-341690-h8fqijk5	300	1	The	the	DT
cord-341690-h8fqijk5	300	2	complete	complete	JJ
cord-341690-h8fqijk5	300	3	genome	genome	NN
cord-341690-h8fqijk5	300	4	sequence	sequence	NN
cord-341690-h8fqijk5	300	5	for	for	IN
cord-341690-h8fqijk5	300	6	TGEV	TGEV	NNP
cord-341690-h8fqijk5	300	7	SHXB	SHXB	NNP
cord-341690-h8fqijk5	300	8	is	be	VBZ
cord-341690-h8fqijk5	300	9	available	available	JJ
cord-341690-h8fqijk5	300	10	in	in	IN
cord-341690-h8fqijk5	300	11	GenBank	GenBank	NNP
cord-341690-h8fqijk5	300	12	(	(	-LRB-
cord-341690-h8fqijk5	300	13	KP202848.1	KP202848.1	NNP
cord-341690-h8fqijk5	300	14	)	)	-RRB-
cord-341690-h8fqijk5	300	15	[	[	-LRB-
cord-341690-h8fqijk5	300	16	50	50	CD
cord-341690-h8fqijk5	300	17	]	]	-RRB-
cord-341690-h8fqijk5	300	18	.	.	.
cord-341690-h8fqijk5	301	1	For	for	IN
cord-341690-h8fqijk5	301	2	the	the	DT
cord-341690-h8fqijk5	301	3	binding	bind	VBG
cord-341690-h8fqijk5	301	4	assays	assay	NNS
cord-341690-h8fqijk5	301	5	,	,	,
cord-341690-h8fqijk5	301	6	cells	cell	NNS
cord-341690-h8fqijk5	301	7	were	be	VBD
cord-341690-h8fqijk5	301	8	incubated	incubate	VBN
cord-341690-h8fqijk5	301	9	with	with	IN
cord-341690-h8fqijk5	301	10	TGEV	TGEV	NNS
cord-341690-h8fqijk5	301	11	at	at	IN
cord-341690-h8fqijk5	301	12	a	a	DT
cord-341690-h8fqijk5	301	13	multiplicity	multiplicity	NN
cord-341690-h8fqijk5	301	14	of	of	IN
cord-341690-h8fqijk5	301	15	infection	infection	NN
cord-341690-h8fqijk5	301	16	of	of	IN
cord-341690-h8fqijk5	301	17	2	2	CD
cord-341690-h8fqijk5	301	18	(	(	-LRB-
cord-341690-h8fqijk5	301	19	MOI	MOI	NNP
cord-341690-h8fqijk5	301	20	=	=	SYM
cord-341690-h8fqijk5	301	21	2	2	CD
cord-341690-h8fqijk5	301	22	)	)	-RRB-
cord-341690-h8fqijk5	301	23	for	for	IN
cord-341690-h8fqijk5	301	24	1	1	CD
cord-341690-h8fqijk5	301	25	h	h	NN
cord-341690-h8fqijk5	301	26	at	at	IN
cord-341690-h8fqijk5	301	27	4	4	CD
cord-341690-h8fqijk5	301	28	°	°	NN
cord-341690-h8fqijk5	301	29	C	c	NN
cord-341690-h8fqijk5	301	30	,	,	,
cord-341690-h8fqijk5	301	31	and	and	CC
cord-341690-h8fqijk5	301	32	washed	wash	VBD
cord-341690-h8fqijk5	301	33	with	with	IN
cord-341690-h8fqijk5	301	34	PBS	PBS	NNP
cord-341690-h8fqijk5	301	35	(	(	-LRB-
cord-341690-h8fqijk5	301	36	pH7.2	ph7.2	NN
cord-341690-h8fqijk5	301	37	at	at	IN
cord-341690-h8fqijk5	301	38	4	4	CD
cord-341690-h8fqijk5	301	39	°	°	NN
cord-341690-h8fqijk5	301	40	C	c	NN
cord-341690-h8fqijk5	301	41	)	)	-RRB-
cord-341690-h8fqijk5	301	42	three	three	CD
cord-341690-h8fqijk5	301	43	times	time	NNS
cord-341690-h8fqijk5	301	44	to	to	TO
cord-341690-h8fqijk5	301	45	remove	remove	VB
cord-341690-h8fqijk5	301	46	unbound	unbound	JJ
cord-341690-h8fqijk5	301	47	virus	virus	NN
cord-341690-h8fqijk5	301	48	,	,	,
cord-341690-h8fqijk5	301	49	then	then	RB
cord-341690-h8fqijk5	301	50	we	-PRON-	PRP
cord-341690-h8fqijk5	301	51	added	add	VBD
cord-341690-h8fqijk5	301	52	the	the	DT
cord-341690-h8fqijk5	301	53	Trizol	Trizol	NNP
cord-341690-h8fqijk5	301	54	to	to	TO
cord-341690-h8fqijk5	301	55	collect	collect	VB
cord-341690-h8fqijk5	301	56	the	the	DT
cord-341690-h8fqijk5	301	57	samples	sample	NNS
cord-341690-h8fqijk5	301	58	.	.	.
cord-341690-h8fqijk5	302	1	For	for	IN
cord-341690-h8fqijk5	302	2	the	the	DT
cord-341690-h8fqijk5	302	3	entry	entry	NN
cord-341690-h8fqijk5	302	4	assays	assay	NNS
cord-341690-h8fqijk5	302	5	,	,	,
cord-341690-h8fqijk5	302	6	cells	cell	NNS
cord-341690-h8fqijk5	302	7	were	be	VBD
cord-341690-h8fqijk5	302	8	incubated	incubate	VBN
cord-341690-h8fqijk5	302	9	with	with	IN
cord-341690-h8fqijk5	302	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	302	11	at	at	IN
cord-341690-h8fqijk5	302	12	MOI	MOI	NNP
cord-341690-h8fqijk5	302	13	=	=	SYM
cord-341690-h8fqijk5	302	14	2	2	CD
cord-341690-h8fqijk5	302	15	for	for	IN
cord-341690-h8fqijk5	302	16	1	1	CD
cord-341690-h8fqijk5	302	17	h	h	NN
cord-341690-h8fqijk5	302	18	at	at	IN
cord-341690-h8fqijk5	302	19	4	4	CD
cord-341690-h8fqijk5	302	20	°	°	NN
cord-341690-h8fqijk5	302	21	C	c	NN
cord-341690-h8fqijk5	302	22	and	and	CC
cord-341690-h8fqijk5	302	23	washed	wash	VBD
cord-341690-h8fqijk5	302	24	with	with	IN
cord-341690-h8fqijk5	302	25	PBS	PBS	NNP
cord-341690-h8fqijk5	302	26	(	(	-LRB-
cord-341690-h8fqijk5	302	27	pH7.2	ph7.2	NN
cord-341690-h8fqijk5	302	28	at	at	IN
cord-341690-h8fqijk5	302	29	4	4	CD
cord-341690-h8fqijk5	302	30	°	°	NN
cord-341690-h8fqijk5	302	31	C	c	NN
cord-341690-h8fqijk5	302	32	)	)	-RRB-
cord-341690-h8fqijk5	302	33	three	three	CD
cord-341690-h8fqijk5	302	34	times	time	NNS
cord-341690-h8fqijk5	302	35	to	to	TO
cord-341690-h8fqijk5	302	36	remove	remove	VB
cord-341690-h8fqijk5	302	37	unbound	unbound	JJ
cord-341690-h8fqijk5	302	38	virus	virus	NN
cord-341690-h8fqijk5	302	39	,	,	,
cord-341690-h8fqijk5	302	40	then	then	RB
cord-341690-h8fqijk5	302	41	maintained	maintain	VBD
cord-341690-h8fqijk5	302	42	in	in	IN
cord-341690-h8fqijk5	302	43	maintenance	maintenance	NN
cord-341690-h8fqijk5	302	44	medium	medium	NN
cord-341690-h8fqijk5	302	45	(	(	-LRB-
cord-341690-h8fqijk5	302	46	DMEM	DMEM	NNP
cord-341690-h8fqijk5	302	47	supplemented	supplement	VBD
cord-341690-h8fqijk5	302	48	with	with	IN
cord-341690-h8fqijk5	302	49	2	2	CD
cord-341690-h8fqijk5	302	50	%	%	NN
cord-341690-h8fqijk5	302	51	FBS	FBS	NNP
cord-341690-h8fqijk5	302	52	and	and	CC
cord-341690-h8fqijk5	302	53	1	1	CD
cord-341690-h8fqijk5	302	54	%	%	NN
cord-341690-h8fqijk5	302	55	penicillinstreptomycin	penicillinstreptomycin	NNS
cord-341690-h8fqijk5	302	56	)	)	-RRB-
cord-341690-h8fqijk5	302	57	at	at	IN
cord-341690-h8fqijk5	302	58	37	37	CD
cord-341690-h8fqijk5	302	59	°	°	NN
cord-341690-h8fqijk5	302	60	C	c	NN
cord-341690-h8fqijk5	302	61	in	in	IN
cord-341690-h8fqijk5	302	62	a	a	DT
cord-341690-h8fqijk5	302	63	5	5	CD
cord-341690-h8fqijk5	302	64	%	%	NN
cord-341690-h8fqijk5	302	65	CO	co	NN
cord-341690-h8fqijk5	302	66	2	2	CD
cord-341690-h8fqijk5	302	67	incubator	incubator	NN
cord-341690-h8fqijk5	302	68	,	,	,
cord-341690-h8fqijk5	302	69	after	after	IN
cord-341690-h8fqijk5	302	70	the	the	DT
cord-341690-h8fqijk5	302	71	indicated	indicate	VBN
cord-341690-h8fqijk5	302	72	time	time	NN
cord-341690-h8fqijk5	302	73	,	,	,
cord-341690-h8fqijk5	302	74	cells	cell	NNS
cord-341690-h8fqijk5	302	75	were	be	VBD
cord-341690-h8fqijk5	302	76	washed	wash	VBN
cord-341690-h8fqijk5	302	77	with	with	IN
cord-341690-h8fqijk5	302	78	acidic	acidic	JJ
cord-341690-h8fqijk5	302	79	PBS	PBS	NNP
cord-341690-h8fqijk5	302	80	(	(	-LRB-
cord-341690-h8fqijk5	302	81	pH	pH	NNP
cord-341690-h8fqijk5	302	82	3.0	3.0	CD
cord-341690-h8fqijk5	302	83	at	at	IN
cord-341690-h8fqijk5	302	84	4	4	CD
cord-341690-h8fqijk5	302	85	°	°	NN
cord-341690-h8fqijk5	302	86	C	c	NN
cord-341690-h8fqijk5	302	87	)	)	-RRB-
cord-341690-h8fqijk5	302	88	to	to	TO
cord-341690-h8fqijk5	302	89	remove	remove	VB
cord-341690-h8fqijk5	302	90	the	the	DT
cord-341690-h8fqijk5	302	91	virus	virus	NN
cord-341690-h8fqijk5	302	92	bound	bind	VBN
cord-341690-h8fqijk5	302	93	to	to	IN
cord-341690-h8fqijk5	302	94	the	the	DT
cord-341690-h8fqijk5	302	95	cell	cell	NN
cord-341690-h8fqijk5	302	96	membrane	membrane	NN
cord-341690-h8fqijk5	302	97	(	(	-LRB-
cord-341690-h8fqijk5	302	98	not	not	RB
cord-341690-h8fqijk5	302	99	enter	enter	VB
cord-341690-h8fqijk5	302	100	the	the	DT
cord-341690-h8fqijk5	302	101	cell	cell	NN
cord-341690-h8fqijk5	302	102	)	)	-RRB-
cord-341690-h8fqijk5	302	103	,	,	,
cord-341690-h8fqijk5	302	104	then	then	RB
cord-341690-h8fqijk5	302	105	we	-PRON-	PRP
cord-341690-h8fqijk5	302	106	added	add	VBD
cord-341690-h8fqijk5	302	107	the	the	DT
cord-341690-h8fqijk5	302	108	Trizol	Trizol	NNP
cord-341690-h8fqijk5	302	109	to	to	TO
cord-341690-h8fqijk5	302	110	collect	collect	VB
cord-341690-h8fqijk5	302	111	the	the	DT
cord-341690-h8fqijk5	302	112	samples	sample	NNS
cord-341690-h8fqijk5	302	113	.	.	.
cord-341690-h8fqijk5	303	1	Total	Total	NNP
cord-341690-h8fqijk5	303	2	RNA	RNA	NNP
cord-341690-h8fqijk5	303	3	from	from	IN
cord-341690-h8fqijk5	303	4	IPEC	IPEC	NNP
cord-341690-h8fqijk5	303	5	-	-	HYPH
cord-341690-h8fqijk5	303	6	J2	J2	NNP
cord-341690-h8fqijk5	303	7	cells	cell	NNS
cord-341690-h8fqijk5	303	8	infected	infect	VBN
cord-341690-h8fqijk5	303	9	with	with	IN
cord-341690-h8fqijk5	303	10	TGEV	TGEV	NNP
cord-341690-h8fqijk5	303	11	was	be	VBD
cord-341690-h8fqijk5	303	12	extracted	extract	VBN
cord-341690-h8fqijk5	303	13	using	use	VBG
cord-341690-h8fqijk5	303	14	TRIzol	TRIzol	NNP
cord-341690-h8fqijk5	303	15	Reagent	Reagent	NNP
cord-341690-h8fqijk5	303	16	(	(	-LRB-
cord-341690-h8fqijk5	303	17	Invitrogen	Invitrogen	NNP
cord-341690-h8fqijk5	303	18	)	)	-RRB-
cord-341690-h8fqijk5	303	19	according	accord	VBG
cord-341690-h8fqijk5	303	20	to	to	IN
cord-341690-h8fqijk5	303	21	the	the	DT
cord-341690-h8fqijk5	303	22	manufacturer	manufacturer	NN
cord-341690-h8fqijk5	303	23	's	's	POS
cord-341690-h8fqijk5	303	24	instructions	instruction	NNS
cord-341690-h8fqijk5	303	25	.	.	.
cord-341690-h8fqijk5	304	1	The	the	DT
cord-341690-h8fqijk5	304	2	cDNA	cdna	NN
cord-341690-h8fqijk5	304	3	was	be	VBD
cord-341690-h8fqijk5	304	4	generated	generate	VBN
cord-341690-h8fqijk5	304	5	by	by	IN
cord-341690-h8fqijk5	304	6	reverse	reverse	JJ
cord-341690-h8fqijk5	304	7	transcription	transcription	NN
cord-341690-h8fqijk5	304	8	using	use	VBG
cord-341690-h8fqijk5	304	9	HiScript	HiScript	NNP
cord-341690-h8fqijk5	304	10	TM	TM	NNP
cord-341690-h8fqijk5	304	11	QRT	QRT	NNP
cord-341690-h8fqijk5	304	12	SuperMix	SuperMix	NNP
cord-341690-h8fqijk5	304	13	for	for	IN
cord-341690-h8fqijk5	304	14	qPCR	qpcr	FW
cord-341690-h8fqijk5	304	15	(	(	-LRB-
cord-341690-h8fqijk5	304	16	Vazyme	Vazyme	NNP
cord-341690-h8fqijk5	304	17	)	)	-RRB-
cord-341690-h8fqijk5	304	18	according	accord	VBG
cord-341690-h8fqijk5	304	19	to	to	IN
cord-341690-h8fqijk5	304	20	the	the	DT
cord-341690-h8fqijk5	304	21	manufacturer	manufacturer	NN
cord-341690-h8fqijk5	304	22	's	's	POS
cord-341690-h8fqijk5	304	23	instructions	instruction	NNS
cord-341690-h8fqijk5	304	24	.	.	.
cord-341690-h8fqijk5	305	1	TGEV	TGEV	NNP
cord-341690-h8fqijk5	305	2	entry	entry	NN
cord-341690-h8fqijk5	305	3	and	and	CC
cord-341690-h8fqijk5	305	4	binding	binding	NN
cord-341690-h8fqijk5	305	5	were	be	VBD
cord-341690-h8fqijk5	305	6	assessed	assess	VBN
cord-341690-h8fqijk5	305	7	by	by	IN
cord-341690-h8fqijk5	305	8	detecting	detect	VBG
cord-341690-h8fqijk5	305	9	the	the	DT
cord-341690-h8fqijk5	305	10	viral	viral	JJ
cord-341690-h8fqijk5	305	11	nucleoprotein	nucleoprotein	NNP
cord-341690-h8fqijk5	305	12	(	(	-LRB-
cord-341690-h8fqijk5	305	13	N	N	NNP
cord-341690-h8fqijk5	305	14	)	)	-RRB-
cord-341690-h8fqijk5	305	15	gene	gene	NN
cord-341690-h8fqijk5	305	16	using	use	VBG
cord-341690-h8fqijk5	305	17	quantitative	quantitative	JJ
cord-341690-h8fqijk5	305	18	RT	RT	NNP
cord-341690-h8fqijk5	305	19	-	-	HYPH
cord-341690-h8fqijk5	305	20	PCR	PCR	NNP
cord-341690-h8fqijk5	305	21	with	with	IN
cord-341690-h8fqijk5	305	22	the	the	DT
cord-341690-h8fqijk5	305	23	TaKaRa	takara	XX
cord-341690-h8fqijk5	305	24	SYBR	SYBR	NNP
cord-341690-h8fqijk5	305	25	Green	Green	NNP
cord-341690-h8fqijk5	305	26	qPCR	qpcr	NN
cord-341690-h8fqijk5	305	27	Kit	kit	NN
cord-341690-h8fqijk5	305	28	(	(	-LRB-
cord-341690-h8fqijk5	305	29	TaKaRa	TaKaRa	NNP
cord-341690-h8fqijk5	305	30	)	)	-RRB-
cord-341690-h8fqijk5	305	31	.	.	.
cord-341690-h8fqijk5	306	1	Primer	primer	NN
cord-341690-h8fqijk5	306	2	sequences	sequence	NNS
cord-341690-h8fqijk5	306	3	were	be	VBD
cord-341690-h8fqijk5	306	4	as	as	IN
cord-341690-h8fqijk5	306	5	follows	follow	VBZ
cord-341690-h8fqijk5	306	6	:	:	:
cord-341690-h8fqijk5	307	1	N	N	NNP
cord-341690-h8fqijk5	307	2	-	-	HYPH
cord-341690-h8fqijk5	307	3	F	F	NNP
cord-341690-h8fqijk5	307	4	(	(	-LRB-
cord-341690-h8fqijk5	307	5	sense	sense	NN
cord-341690-h8fqijk5	307	6	)	)	-RRB-
cord-341690-h8fqijk5	307	7	,	,	,
cord-341690-h8fqijk5	307	8	5'-CAATTCCCGTGGTCGGAAGA-3	5'-caattcccgtggtcggaaga-3	CD
cord-341690-h8fqijk5	307	9	'	'	''
cord-341690-h8fqijk5	307	10	;	;	:
cord-341690-h8fqijk5	307	11	N	n	CD
cord-341690-h8fqijk5	307	12	-	-	HYPH
cord-341690-h8fqijk5	307	13	R	R	NNP
cord-341690-h8fqijk5	307	14	(	(	-LRB-
cord-341690-h8fqijk5	307	15	antisense	antisense	NN
cord-341690-h8fqijk5	307	16	)	)	-RRB-
cord-341690-h8fqijk5	307	17	,	,	,
cord-341690-h8fqijk5	307	18	5'-TTTACGTTGGCCCTTCACCA-3	5'-tttacgttggcccttcacca-3	CD
cord-341690-h8fqijk5	307	19	'	'	''
cord-341690-h8fqijk5	307	20	;	;	:
cord-341690-h8fqijk5	307	21	GAPDH	GAPDH	NNP
cord-341690-h8fqijk5	307	22	-	-	HYPH
cord-341690-h8fqijk5	307	23	F	F	NNP
cord-341690-h8fqijk5	307	24	,	,	,
cord-341690-h8fqijk5	307	25	5'-TCATCATCTCTGCCCCTTCT-3	5'-tcatcatctctgccccttct-3	CD
cord-341690-h8fqijk5	307	26	'	'	''
cord-341690-h8fqijk5	307	27	;	;	:
cord-341690-h8fqijk5	307	28	GAPDH	GAPDH	NNP
cord-341690-h8fqijk5	307	29	-	-	HYPH
cord-341690-h8fqijk5	307	30	R	R	NNP
cord-341690-h8fqijk5	307	31	,	,	,
cord-341690-h8fqijk5	307	32	5'-GTCATGAGTCCCTCCACGAT-3	5'-gtcatgagtccctccacgat-3	CD
cord-341690-h8fqijk5	307	33	'	'	''
cord-341690-h8fqijk5	307	34	.	.	.
cord-341690-h8fqijk5	308	1	PCR	PCR	NNP
cord-341690-h8fqijk5	308	2	products	product	NNS
cord-341690-h8fqijk5	308	3	were	be	VBD
cord-341690-h8fqijk5	308	4	purified	purify	VBN
cord-341690-h8fqijk5	308	5	using	use	VBG
cord-341690-h8fqijk5	308	6	a	a	DT
cord-341690-h8fqijk5	308	7	Gel	Gel	NNP
cord-341690-h8fqijk5	308	8	Extraction	extraction	NN
cord-341690-h8fqijk5	308	9	Kit	kit	NN
cord-341690-h8fqijk5	308	10	(	(	-LRB-
cord-341690-h8fqijk5	308	11	Omega	Omega	NNP
cord-341690-h8fqijk5	308	12	)	)	-RRB-
cord-341690-h8fqijk5	308	13	,	,	,
cord-341690-h8fqijk5	308	14	and	and	CC
cord-341690-h8fqijk5	308	15	cloned	clone	VBN
cord-341690-h8fqijk5	308	16	into	into	IN
cord-341690-h8fqijk5	308	17	the	the	DT
cord-341690-h8fqijk5	308	18	pJET1.2	pjet1.2	NN
cord-341690-h8fqijk5	308	19	vector	vector	NN
cord-341690-h8fqijk5	308	20	(	(	-LRB-
cord-341690-h8fqijk5	308	21	Thermo	Thermo	NNP
cord-341690-h8fqijk5	308	22	)	)	-RRB-
cord-341690-h8fqijk5	308	23	.	.	.
cord-341690-h8fqijk5	309	1	Plasmids	plasmid	NNS
cord-341690-h8fqijk5	309	2	were	be	VBD
cord-341690-h8fqijk5	309	3	diluted	dilute	VBN
cord-341690-h8fqijk5	309	4	serially	serially	RB
cord-341690-h8fqijk5	309	5	and	and	CC
cord-341690-h8fqijk5	309	6	used	use	VBN
cord-341690-h8fqijk5	309	7	as	as	IN
cord-341690-h8fqijk5	309	8	standards	standard	NNS
cord-341690-h8fqijk5	309	9	for	for	IN
cord-341690-h8fqijk5	309	10	quantitative	quantitative	JJ
cord-341690-h8fqijk5	309	11	analysis	analysis	NN
cord-341690-h8fqijk5	309	12	.	.	.
cord-341690-h8fqijk5	310	1	The	the	DT
cord-341690-h8fqijk5	310	2	initial	initial	JJ
cord-341690-h8fqijk5	310	3	copy	copy	NN
cord-341690-h8fqijk5	310	4	number	number	NN
cord-341690-h8fqijk5	310	5	of	of	IN
cord-341690-h8fqijk5	310	6	TGEV	TGEV	NNP
cord-341690-h8fqijk5	310	7	N	n	CD
cord-341690-h8fqijk5	310	8	gene	gene	NN
cord-341690-h8fqijk5	310	9	and	and	CC
cord-341690-h8fqijk5	310	10	GAPDH	GAPDH	NNP
cord-341690-h8fqijk5	310	11	in	in	IN
cord-341690-h8fqijk5	310	12	each	each	DT
cord-341690-h8fqijk5	310	13	group	group	NN
cord-341690-h8fqijk5	310	14	was	be	VBD
cord-341690-h8fqijk5	310	15	calculated	calculate	VBN
cord-341690-h8fqijk5	310	16	using	use	VBG
cord-341690-h8fqijk5	310	17	the	the	DT
cord-341690-h8fqijk5	310	18	following	following	JJ
cord-341690-h8fqijk5	310	19	formula	formula	NN
cord-341690-h8fqijk5	310	20	:	:	:
cord-341690-h8fqijk5	310	21	X0	x0	NN
cord-341690-h8fqijk5	310	22	=	=	NFP
cord-341690-h8fqijk5	311	1	-K	-K	:
cord-341690-h8fqijk5	311	2	log	log	NNP
cord-341690-h8fqijk5	311	3	Ct	Ct	NNP
cord-341690-h8fqijk5	312	1	+	+	CC
cord-341690-h8fqijk5	313	1	b	b	LS
cord-341690-h8fqijk5	313	2	,	,	,
cord-341690-h8fqijk5	313	3	where	where	WRB
cord-341690-h8fqijk5	313	4	X0	x0	NN
cord-341690-h8fqijk5	313	5	is	be	VBZ
cord-341690-h8fqijk5	313	6	the	the	DT
cord-341690-h8fqijk5	313	7	initial	initial	JJ
cord-341690-h8fqijk5	313	8	copy	copy	NN
cord-341690-h8fqijk5	313	9	number	number	NN
cord-341690-h8fqijk5	313	10	,	,	,
cord-341690-h8fqijk5	313	11	K	K	NNP
cord-341690-h8fqijk5	313	12	,	,	,
cord-341690-h8fqijk5	313	13	Ct	Ct	NNP
cord-341690-h8fqijk5	313	14	,	,	,
cord-341690-h8fqijk5	313	15	and	and	CC
cord-341690-h8fqijk5	313	16	b	b	LS
cord-341690-h8fqijk5	313	17	refer	refer	VB
cord-341690-h8fqijk5	313	18	to	to	IN
cord-341690-h8fqijk5	313	19	the	the	DT
cord-341690-h8fqijk5	313	20	slope	slope	NN
cord-341690-h8fqijk5	313	21	rate	rate	NN
cord-341690-h8fqijk5	313	22	,	,	,
cord-341690-h8fqijk5	313	23	cycle	cycle	NN
cord-341690-h8fqijk5	313	24	threshold	threshold	NN
cord-341690-h8fqijk5	313	25	,	,	,
cord-341690-h8fqijk5	313	26	and	and	CC
cord-341690-h8fqijk5	313	27	constant	constant	JJ
cord-341690-h8fqijk5	313	28	,	,	,
cord-341690-h8fqijk5	313	29	respectively	respectively	RB
cord-341690-h8fqijk5	313	30	.	.	.
cord-341690-h8fqijk5	314	1	Quantitative	quantitative	JJ
cord-341690-h8fqijk5	314	2	real	real	JJ
cord-341690-h8fqijk5	314	3	-	-	HYPH
cord-341690-h8fqijk5	314	4	time	time	NN
cord-341690-h8fqijk5	314	5	PCR	PCR	NNP
cord-341690-h8fqijk5	314	6	was	be	VBD
cord-341690-h8fqijk5	314	7	performed	perform	VBN
cord-341690-h8fqijk5	314	8	with	with	IN
cord-341690-h8fqijk5	314	9	the	the	DT
cord-341690-h8fqijk5	314	10	ABI	ABI	NNP
cord-341690-h8fqijk5	314	11	PRISM	PRISM	NNP
cord-341690-h8fqijk5	314	12	7500	7500	CD
cord-341690-h8fqijk5	314	13	Detection	Detection	NNP
cord-341690-h8fqijk5	314	14	System	System	NNP
cord-341690-h8fqijk5	314	15	(	(	-LRB-
cord-341690-h8fqijk5	314	16	Applied	Applied	NNP
cord-341690-h8fqijk5	314	17	Biosystems	Biosystems	NNP
cord-341690-h8fqijk5	314	18	,	,	,
cord-341690-h8fqijk5	314	19	Foster	Foster	NNP
cord-341690-h8fqijk5	314	20	,	,	,
cord-341690-h8fqijk5	314	21	USA	USA	NNP
cord-341690-h8fqijk5	314	22	)	)	-RRB-
cord-341690-h8fqijk5	314	23	.	.	.
cord-341690-h8fqijk5	315	1	At	at	IN
cord-341690-h8fqijk5	315	2	indicated	indicate	VBN
cord-341690-h8fqijk5	315	3	times	time	NNS
cord-341690-h8fqijk5	315	4	post	post	JJ
cord-341690-h8fqijk5	315	5	infection	infection	NN
cord-341690-h8fqijk5	315	6	,	,	,
cord-341690-h8fqijk5	315	7	cells	cell	NNS
cord-341690-h8fqijk5	315	8	were	be	VBD
cord-341690-h8fqijk5	315	9	washed	wash	VBN
cord-341690-h8fqijk5	315	10	with	with	IN
cord-341690-h8fqijk5	315	11	PBS	PBS	NNP
cord-341690-h8fqijk5	315	12	and	and	CC
cord-341690-h8fqijk5	315	13	lysed	lyse	VBN
cord-341690-h8fqijk5	315	14	in	in	IN
cord-341690-h8fqijk5	315	15	radioimmunoprecipitation	radioimmunoprecipitation	NN
cord-341690-h8fqijk5	315	16	assay	assay	NN
cord-341690-h8fqijk5	315	17	(	(	-LRB-
cord-341690-h8fqijk5	315	18	RIPA	RIPA	NNP
cord-341690-h8fqijk5	315	19	)	)	-RRB-
cord-341690-h8fqijk5	315	20	buffer	buffer	NN
cord-341690-h8fqijk5	315	21	(	(	-LRB-
cord-341690-h8fqijk5	315	22	Thermo	Thermo	NNP
cord-341690-h8fqijk5	315	23	Scientific	Scientific	NNP
cord-341690-h8fqijk5	315	24	)	)	-RRB-
cord-341690-h8fqijk5	315	25	.	.	.
cord-341690-h8fqijk5	316	1	Phosphatase	phosphatase	JJ
cord-341690-h8fqijk5	316	2	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	316	3	and	and	CC
cord-341690-h8fqijk5	316	4	Protease	Protease	NNP
cord-341690-h8fqijk5	316	5	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	316	6	(	(	-LRB-
cord-341690-h8fqijk5	316	7	Thermo	Thermo	NNP
cord-341690-h8fqijk5	316	8	Scientific	Scientific	NNP
cord-341690-h8fqijk5	316	9	)	)	-RRB-
cord-341690-h8fqijk5	316	10	were	be	VBD
cord-341690-h8fqijk5	316	11	added	add	VBN
cord-341690-h8fqijk5	316	12	in	in	IN
cord-341690-h8fqijk5	316	13	the	the	DT
cord-341690-h8fqijk5	316	14	RIPA	RIPA	NNP
cord-341690-h8fqijk5	316	15	according	accord	VBG
cord-341690-h8fqijk5	316	16	to	to	IN
cord-341690-h8fqijk5	316	17	the	the	DT
cord-341690-h8fqijk5	316	18	manufacturer	manufacturer	NN
cord-341690-h8fqijk5	316	19	's	's	POS
cord-341690-h8fqijk5	316	20	instructions	instruction	NNS
cord-341690-h8fqijk5	316	21	.	.	.
cord-341690-h8fqijk5	317	1	The	the	DT
cord-341690-h8fqijk5	317	2	concentration	concentration	NN
cord-341690-h8fqijk5	317	3	of	of	IN
cord-341690-h8fqijk5	317	4	the	the	DT
cord-341690-h8fqijk5	317	5	lysates	lysate	NNS
cord-341690-h8fqijk5	317	6	were	be	VBD
cord-341690-h8fqijk5	317	7	determined	determine	VBN
cord-341690-h8fqijk5	317	8	by	by	IN
cord-341690-h8fqijk5	317	9	a	a	DT
cord-341690-h8fqijk5	317	10	Pierce	Pierce	NNP
cord-341690-h8fqijk5	317	11	BCA	BCA	NNP
cord-341690-h8fqijk5	317	12	Protein	Protein	NNP
cord-341690-h8fqijk5	317	13	Assay	Assay	NNP
cord-341690-h8fqijk5	317	14	kit	kit	NN
cord-341690-h8fqijk5	317	15	based	base	VBN
cord-341690-h8fqijk5	317	16	on	on	IN
cord-341690-h8fqijk5	317	17	the	the	DT
cord-341690-h8fqijk5	317	18	bicinchoninic	bicinchoninic	NNP
cord-341690-h8fqijk5	317	19	acid	acid	NNP
cord-341690-h8fqijk5	317	20	spectrophotometric	spectrophotometric	NNP
cord-341690-h8fqijk5	317	21	method	method	NN
cord-341690-h8fqijk5	317	22	(	(	-LRB-
cord-341690-h8fqijk5	317	23	Thermo	Thermo	NNP
cord-341690-h8fqijk5	317	24	Scientific	Scientific	NNP
cord-341690-h8fqijk5	317	25	)	)	-RRB-
cord-341690-h8fqijk5	317	26	.	.	.
cord-341690-h8fqijk5	318	1	After	after	IN
cord-341690-h8fqijk5	318	2	centrifugation	centrifugation	NN
cord-341690-h8fqijk5	318	3	at	at	IN
cord-341690-h8fqijk5	318	4	12000×g	12000×g	CD
cord-341690-h8fqijk5	318	5	for	for	IN
cord-341690-h8fqijk5	318	6	10	10	CD
cord-341690-h8fqijk5	318	7	min	min	NN
cord-341690-h8fqijk5	318	8	,	,	,
cord-341690-h8fqijk5	318	9	the	the	DT
cord-341690-h8fqijk5	318	10	supernatant	supernatant	NN
cord-341690-h8fqijk5	318	11	(	(	-LRB-
cord-341690-h8fqijk5	318	12	15	15	CD
cord-341690-h8fqijk5	318	13	-	-	SYM
cord-341690-h8fqijk5	318	14	50	50	CD
cord-341690-h8fqijk5	318	15	ug	ug	NNS
cord-341690-h8fqijk5	318	16	of	of	IN
cord-341690-h8fqijk5	318	17	protein	protein	NN
cord-341690-h8fqijk5	318	18	)	)	-RRB-
cord-341690-h8fqijk5	318	19	was	be	VBD
cord-341690-h8fqijk5	318	20	fractionated	fractionate	VBN
cord-341690-h8fqijk5	318	21	by	by	IN
cord-341690-h8fqijk5	318	22	SDS	SDS	NNP
cord-341690-h8fqijk5	318	23	-	-	HYPH
cord-341690-h8fqijk5	318	24	PAGE	PAGE	NNP
cord-341690-h8fqijk5	318	25	(	(	-LRB-
cord-341690-h8fqijk5	318	26	10%-12	10%-12	CD
cord-341690-h8fqijk5	318	27	%	%	NN
cord-341690-h8fqijk5	318	28	gradient	gradient	NN
cord-341690-h8fqijk5	318	29	)	)	-RRB-
cord-341690-h8fqijk5	318	30	,	,	,
cord-341690-h8fqijk5	318	31	the	the	DT
cord-341690-h8fqijk5	318	32	separated	separate	VBN
cord-341690-h8fqijk5	318	33	proteins	protein	NNS
cord-341690-h8fqijk5	318	34	were	be	VBD
cord-341690-h8fqijk5	318	35	transferred	transfer	VBN
cord-341690-h8fqijk5	318	36	to	to	IN
cord-341690-h8fqijk5	318	37	PVDF	PVDF	NNP
cord-341690-h8fqijk5	318	38	(	(	-LRB-
cord-341690-h8fqijk5	318	39	Merck	Merck	NNP
cord-341690-h8fqijk5	318	40	Millipore	Millipore	NNP
cord-341690-h8fqijk5	318	41	)	)	-RRB-
cord-341690-h8fqijk5	318	42	,	,	,
cord-341690-h8fqijk5	318	43	the	the	DT
cord-341690-h8fqijk5	318	44	membranes	membrane	NNS
cord-341690-h8fqijk5	318	45	were	be	VBD
cord-341690-h8fqijk5	318	46	blocked	block	VBN
cord-341690-h8fqijk5	318	47	for	for	IN
cord-341690-h8fqijk5	318	48	2h	2h	CD
cord-341690-h8fqijk5	318	49	in	in	IN
cord-341690-h8fqijk5	318	50	Tris	Tris	NNP
cord-341690-h8fqijk5	318	51	-	-	HYPH
cord-341690-h8fqijk5	318	52	buffered	buffer	VBN
cord-341690-h8fqijk5	318	53	saline	saline	NN
cord-341690-h8fqijk5	318	54	(	(	-LRB-
cord-341690-h8fqijk5	318	55	TBS	TBS	NNP
cord-341690-h8fqijk5	318	56	)	)	-RRB-
cord-341690-h8fqijk5	318	57	containing	contain	VBG
cord-341690-h8fqijk5	318	58	5	5	CD
cord-341690-h8fqijk5	318	59	%	%	NN
cord-341690-h8fqijk5	318	60	nonfat	nonfat	JJ
cord-341690-h8fqijk5	318	61	dry	dry	JJ
cord-341690-h8fqijk5	318	62	milk	milk	NN
cord-341690-h8fqijk5	318	63	,	,	,
cord-341690-h8fqijk5	318	64	and	and	CC
cord-341690-h8fqijk5	318	65	reacted	react	VBD
cord-341690-h8fqijk5	318	66	with	with	IN
cord-341690-h8fqijk5	318	67	the	the	DT
cord-341690-h8fqijk5	318	68	indicated	indicate	VBN
cord-341690-h8fqijk5	318	69	primary	primary	JJ
cord-341690-h8fqijk5	318	70	antibodies	antibody	NNS
cord-341690-h8fqijk5	318	71	at	at	IN
cord-341690-h8fqijk5	318	72	4	4	CD
cord-341690-h8fqijk5	318	73	°	°	NN
cord-341690-h8fqijk5	318	74	C	c	NN
cord-341690-h8fqijk5	318	75	overnight	overnight	RB
cord-341690-h8fqijk5	318	76	.	.	.
cord-341690-h8fqijk5	319	1	Membranes	membrane	NNS
cord-341690-h8fqijk5	319	2	were	be	VBD
cord-341690-h8fqijk5	319	3	exposed	expose	VBN
cord-341690-h8fqijk5	319	4	to	to	IN
cord-341690-h8fqijk5	319	5	species	species	VB
cord-341690-h8fqijk5	319	6	specific	specific	JJ
cord-341690-h8fqijk5	319	7	horseradish	horseradish	NN
cord-341690-h8fqijk5	319	8	peroxidase	peroxidase	NN
cord-341690-h8fqijk5	319	9	(	(	-LRB-
cord-341690-h8fqijk5	319	10	HRP)-conjugated	HRP)-conjugated	NNP
cord-341690-h8fqijk5	319	11	secondary	secondary	JJ
cord-341690-h8fqijk5	319	12	antibodies	antibody	NNS
cord-341690-h8fqijk5	319	13	(	(	-LRB-
cord-341690-h8fqijk5	319	14	dilution	dilution	NN
cord-341690-h8fqijk5	319	15	1:5000	1:5000	NNPS
cord-341690-h8fqijk5	319	16	)	)	-RRB-
cord-341690-h8fqijk5	319	17	followed	follow	VBN
cord-341690-h8fqijk5	319	18	by	by	IN
cord-341690-h8fqijk5	319	19	enhanced	enhance	VBN
cord-341690-h8fqijk5	319	20	chemiluminescence	chemiluminescence	NN
cord-341690-h8fqijk5	319	21	(	(	-LRB-
cord-341690-h8fqijk5	319	22	ECL	ECL	NNP
cord-341690-h8fqijk5	319	23	,	,	,
cord-341690-h8fqijk5	319	24	Thermo	Thermo	NNP
cord-341690-h8fqijk5	319	25	Scientific	Scientific	NNP
cord-341690-h8fqijk5	319	26	)	)	-RRB-
cord-341690-h8fqijk5	319	27	detection	detection	NN
cord-341690-h8fqijk5	319	28	by	by	IN
cord-341690-h8fqijk5	319	29	autoradiography	autoradiography	NNP
cord-341690-h8fqijk5	319	30	.	.	.
cord-341690-h8fqijk5	320	1	Western	western	JJ
cord-341690-h8fqijk5	320	2	blotting	blotting	NN
cord-341690-h8fqijk5	320	3	was	be	VBD
cord-341690-h8fqijk5	320	4	quantified	quantify	VBN
cord-341690-h8fqijk5	320	5	by	by	IN
cord-341690-h8fqijk5	320	6	Quantity	Quantity	NNP
cord-341690-h8fqijk5	320	7	One	One	NNP
cord-341690-h8fqijk5	320	8	(	(	-LRB-
cord-341690-h8fqijk5	320	9	Quantity	Quantity	NNP
cord-341690-h8fqijk5	320	10	One	one	CD
cord-341690-h8fqijk5	320	11	1-D	1-D	NNP
cord-341690-h8fqijk5	320	12	Analysis	Analysis	NNP
cord-341690-h8fqijk5	320	13	Software	Software	NNP
cord-341690-h8fqijk5	320	14	170	170	CD
cord-341690-h8fqijk5	320	15	-	-	HYPH
cord-341690-h8fqijk5	320	16	9600	9600	CD
cord-341690-h8fqijk5	320	17	,	,	,
cord-341690-h8fqijk5	320	18	Bio	Bio	NNP
cord-341690-h8fqijk5	320	19	-	-	HYPH
cord-341690-h8fqijk5	320	20	Rad	Rad	NNP
cord-341690-h8fqijk5	320	21	)	)	-RRB-
cord-341690-h8fqijk5	320	22	.	.	.
cord-341690-h8fqijk5	321	1	The	the	DT
cord-341690-h8fqijk5	321	2	intensity	intensity	NN
cord-341690-h8fqijk5	321	3	of	of	IN
cord-341690-h8fqijk5	321	4	the	the	DT
cord-341690-h8fqijk5	321	5	bands	band	NNS
cord-341690-h8fqijk5	321	6	in	in	IN
cord-341690-h8fqijk5	321	7	terms	term	NNS
cord-341690-h8fqijk5	321	8	of	of	IN
cord-341690-h8fqijk5	321	9	density	density	NN
cord-341690-h8fqijk5	321	10	was	be	VBD
cord-341690-h8fqijk5	321	11	measured	measure	VBN
cord-341690-h8fqijk5	321	12	and	and	CC
cord-341690-h8fqijk5	321	13	normalized	normalize	VBN
cord-341690-h8fqijk5	321	14	against	against	IN
cord-341690-h8fqijk5	321	15	GAPDH	GAPDH	NNP
cord-341690-h8fqijk5	321	16	expression	expression	NN
cord-341690-h8fqijk5	321	17	.	.	.
cord-341690-h8fqijk5	322	1	All	all	DT
cord-341690-h8fqijk5	322	2	data	datum	NNS
cord-341690-h8fqijk5	322	3	were	be	VBD
cord-341690-h8fqijk5	322	4	expressed	express	VBN
cord-341690-h8fqijk5	322	5	as	as	IN
cord-341690-h8fqijk5	322	6	means	mean	VBZ
cord-341690-h8fqijk5	322	7	±	±	NNP
cord-341690-h8fqijk5	322	8	SD	SD	NNP
cord-341690-h8fqijk5	322	9	of	of	IN
cord-341690-h8fqijk5	322	10	three	three	CD
cord-341690-h8fqijk5	322	11	independent	independent	JJ
cord-341690-h8fqijk5	322	12	experiments	experiment	NNS
cord-341690-h8fqijk5	322	13	.	.	.
cord-341690-h8fqijk5	323	1	To	to	TO
cord-341690-h8fqijk5	323	2	construct	construct	VB
cord-341690-h8fqijk5	323	3	the	the	DT
cord-341690-h8fqijk5	323	4	pcDNA3.1	pcdna3.1	NN
cord-341690-h8fqijk5	323	5	vectors	vector	NNS
cord-341690-h8fqijk5	323	6	,	,	,
cord-341690-h8fqijk5	323	7	RhoA	RhoA	NNP
cord-341690-h8fqijk5	323	8	,	,	,
cord-341690-h8fqijk5	323	9	Rac1	Rac1	NNP
cord-341690-h8fqijk5	323	10	and	and	CC
cord-341690-h8fqijk5	323	11	Cdc42	Cdc42	NNP
cord-341690-h8fqijk5	323	12	sequences	sequence	NNS
cord-341690-h8fqijk5	323	13	were	be	VBD
cord-341690-h8fqijk5	323	14	inserted	insert	VBN
cord-341690-h8fqijk5	323	15	into	into	IN
cord-341690-h8fqijk5	323	16	the	the	DT
cord-341690-h8fqijk5	323	17	Nhe	Nhe	NNP
cord-341690-h8fqijk5	323	18	I/	I/	NNP
cord-341690-h8fqijk5	323	19	HindIII	HindIII	NNP
cord-341690-h8fqijk5	323	20	site	site	NN
cord-341690-h8fqijk5	323	21	.	.	.
cord-341690-h8fqijk5	324	1	pLVX	plvx	LS
cord-341690-h8fqijk5	324	2	-	-	JJ
cord-341690-h8fqijk5	324	3	DsRed	DsRed	NNP
cord-341690-h8fqijk5	324	4	-	-	HYPH
cord-341690-h8fqijk5	324	5	Monomer	Monomer	NNP
cord-341690-h8fqijk5	324	6	-	-	HYPH
cord-341690-h8fqijk5	324	7	N1	N1	NNP
cord-341690-h8fqijk5	324	8	is	be	VBZ
cord-341690-h8fqijk5	324	9	an	an	DT
cord-341690-h8fqijk5	324	10	HIV-1based	hiv-1based	JJ
cord-341690-h8fqijk5	324	11	,	,	,
cord-341690-h8fqijk5	324	12	lentiviral	lentiviral	JJ
cord-341690-h8fqijk5	324	13	expression	expression	NN
cord-341690-h8fqijk5	324	14	vector	vector	NN
cord-341690-h8fqijk5	324	15	that	that	WDT
cord-341690-h8fqijk5	324	16	express	express	VBP
cord-341690-h8fqijk5	324	17	the	the	DT
cord-341690-h8fqijk5	324	18	gene	gene	NN
cord-341690-h8fqijk5	324	19	of	of	IN
cord-341690-h8fqijk5	324	20	interest	interest	NN
cord-341690-h8fqijk5	324	21	fused	fuse	VBN
cord-341690-h8fqijk5	324	22	to	to	IN
cord-341690-h8fqijk5	324	23	DsRed	DsRed	NNP
cord-341690-h8fqijk5	324	24	-	-	HYPH
cord-341690-h8fqijk5	324	25	Monomer	Monomer	NNP
cord-341690-h8fqijk5	324	26	(	(	-LRB-
cord-341690-h8fqijk5	324	27	Clontech	Clontech	NNP
cord-341690-h8fqijk5	324	28	)	)	-RRB-
cord-341690-h8fqijk5	324	29	.	.	.
cord-341690-h8fqijk5	325	1	RhoA	RhoA	NNP
cord-341690-h8fqijk5	325	2	,	,	,
cord-341690-h8fqijk5	326	1	Rac1	Rac1	NNP
cord-341690-h8fqijk5	326	2	and	and	CC
cord-341690-h8fqijk5	326	3	Cdc42	Cdc42	NNP
cord-341690-h8fqijk5	326	4	sequences	sequence	NNS
cord-341690-h8fqijk5	326	5	were	be	VBD
cord-341690-h8fqijk5	326	6	inserted	insert	VBN
cord-341690-h8fqijk5	326	7	into	into	IN
cord-341690-h8fqijk5	326	8	the	the	DT
cord-341690-h8fqijk5	326	9	EcoRI/	ecori/	JJ
cord-341690-h8fqijk5	326	10	BamHI	BamHI	NNP
cord-341690-h8fqijk5	326	11	site	site	NN
cord-341690-h8fqijk5	326	12	.	.	.
cord-341690-h8fqijk5	327	1	To	to	TO
cord-341690-h8fqijk5	327	2	construct	construct	VB
cord-341690-h8fqijk5	327	3	vectors	vector	NNS
cord-341690-h8fqijk5	327	4	expressing	express	VBG
cord-341690-h8fqijk5	327	5	RhoA	RhoA	NNP
cord-341690-h8fqijk5	327	6	,	,	,
cord-341690-h8fqijk5	327	7	Rac1	Rac1	NNP
cord-341690-h8fqijk5	327	8	,	,	,
cord-341690-h8fqijk5	327	9	and	and	CC
cord-341690-h8fqijk5	327	10	Cdc42	Cdc42	NNP
cord-341690-h8fqijk5	327	11	mutants	mutant	NNS
cord-341690-h8fqijk5	327	12	(	(	-LRB-
cord-341690-h8fqijk5	327	13	constitutively	constitutively	RB
cord-341690-h8fqijk5	327	14	-	-	HYPH
cord-341690-h8fqijk5	327	15	activated	activate	VBN
cord-341690-h8fqijk5	327	16	mutants	mutant	NNS
cord-341690-h8fqijk5	328	1	pLVX	plvx	LS
cord-341690-h8fqijk5	328	2	-	-	HYPH
cord-341690-h8fqijk5	328	3	L63RhoA	L63RhoA	NNP
cord-341690-h8fqijk5	328	4	,	,	,
cord-341690-h8fqijk5	328	5	pLVX	pLVX	VBN
cord-341690-h8fqijk5	328	6	-	-	VBZ
cord-341690-h8fqijk5	328	7	L61Rac1	l61rac1	NN
cord-341690-h8fqijk5	328	8	,	,	,
cord-341690-h8fqijk5	328	9	and	and	CC
cord-341690-h8fqijk5	328	10	pLVX	plvx	LS
cord-341690-h8fqijk5	328	11	-	-	:
cord-341690-h8fqijk5	328	12	L61Cdc42	L61Cdc42	NNS
cord-341690-h8fqijk5	328	13	;	;	:
cord-341690-h8fqijk5	328	14	constitutively	constitutively	RB
cord-341690-h8fqijk5	328	15	-	-	HYPH
cord-341690-h8fqijk5	328	16	inactivated	inactivate	VBN
cord-341690-h8fqijk5	328	17	mutants	mutant	NNS
cord-341690-h8fqijk5	329	1	pLVX	plvx	LS
cord-341690-h8fqijk5	329	2	-	-	NNP
cord-341690-h8fqijk5	329	3	N19RhoA	N19RhoA	NNP
cord-341690-h8fqijk5	329	4	,	,	,
cord-341690-h8fqijk5	329	5	pLVX	pLVX	VBN
cord-341690-h8fqijk5	329	6	-	-	:
cord-341690-h8fqijk5	329	7	N17Rac1	N17Rac1	NNP
cord-341690-h8fqijk5	329	8	,	,	,
cord-341690-h8fqijk5	329	9	and	and	CC
cord-341690-h8fqijk5	329	10	pLVX	plvx	LS
cord-341690-h8fqijk5	329	11	-	-	:
cord-341690-h8fqijk5	329	12	N17Cdc42	N17Cdc42	NNP
cord-341690-h8fqijk5	329	13	)	)	-RRB-
cord-341690-h8fqijk5	329	14	,	,	,
cord-341690-h8fqijk5	329	15	sequences	sequence	NNS
cord-341690-h8fqijk5	329	16	were	be	VBD
cord-341690-h8fqijk5	329	17	amplified	amplify	VBN
cord-341690-h8fqijk5	329	18	from	from	IN
cord-341690-h8fqijk5	329	19	pcDNA3.1-RhoA	pcdna3.1-rhoa	CD
cord-341690-h8fqijk5	329	20	,	,	,
cord-341690-h8fqijk5	329	21	Rac1	Rac1	NNP
cord-341690-h8fqijk5	329	22	,	,	,
cord-341690-h8fqijk5	329	23	and	and	CC
cord-341690-h8fqijk5	329	24	Cdc42	Cdc42	NNP
cord-341690-h8fqijk5	329	25	respectively	respectively	RB
cord-341690-h8fqijk5	329	26	.	.	.
cord-341690-h8fqijk5	330	1	The	the	DT
cord-341690-h8fqijk5	330	2	constitutively	constitutively	RB
cord-341690-h8fqijk5	330	3	-	-	HYPH
cord-341690-h8fqijk5	330	4	phosphorylated	phosphorylated	JJ
cord-341690-h8fqijk5	330	5	mutant	mutant	NN
cord-341690-h8fqijk5	330	6	(	(	-LRB-
cord-341690-h8fqijk5	330	7	inactivated	inactivate	VBN
cord-341690-h8fqijk5	330	8	)	)	-RRB-
cord-341690-h8fqijk5	330	9	pLVX	pLVX	VBN
cord-341690-h8fqijk5	330	10	-	-	HYPH
cord-341690-h8fqijk5	330	11	CofilinS3E	CofilinS3E	NNP
cord-341690-h8fqijk5	330	12	,	,	,
cord-341690-h8fqijk5	330	13	and	and	CC
cord-341690-h8fqijk5	330	14	the	the	DT
cord-341690-h8fqijk5	330	15	constitutively	constitutively	RB
cord-341690-h8fqijk5	330	16	non	non	JJ
cord-341690-h8fqijk5	330	17	-	-	JJ
cord-341690-h8fqijk5	330	18	phosphorylated	phosphorylated	JJ
cord-341690-h8fqijk5	330	19	mutant	mutant	NN
cord-341690-h8fqijk5	330	20	(	(	-LRB-
cord-341690-h8fqijk5	330	21	activated	activate	VBN
cord-341690-h8fqijk5	330	22	)	)	-RRB-
cord-341690-h8fqijk5	330	23	pLVX	pLVX	VBN
cord-341690-h8fqijk5	330	24	-	-	NN
cord-341690-h8fqijk5	330	25	CofilinS3A	CofilinS3A	NNP
cord-341690-h8fqijk5	330	26	,	,	,
cord-341690-h8fqijk5	330	27	were	be	VBD
cord-341690-h8fqijk5	330	28	amplified	amplify	VBN
cord-341690-h8fqijk5	330	29	from	from	IN
cord-341690-h8fqijk5	330	30	pcDNA3.1-cofilin	pcDNA3.1-cofilin	NNP
cord-341690-h8fqijk5	330	31	.	.	.
cord-341690-h8fqijk5	331	1	All	all	DT
cord-341690-h8fqijk5	331	2	mutants	mutant	NNS
cord-341690-h8fqijk5	331	3	were	be	VBD
cord-341690-h8fqijk5	331	4	generated	generate	VBN
cord-341690-h8fqijk5	331	5	using	use	VBG
cord-341690-h8fqijk5	331	6	the	the	DT
cord-341690-h8fqijk5	331	7	Mut	Mut	NNP
cord-341690-h8fqijk5	331	8	Express	Express	NNP
cord-341690-h8fqijk5	331	9	II	II	NNP
cord-341690-h8fqijk5	331	10	Fast	Fast	NNP
cord-341690-h8fqijk5	331	11	Mutagenesis	Mutagenesis	NNP
cord-341690-h8fqijk5	331	12	Kit	kit	NN
cord-341690-h8fqijk5	331	13	(	(	-LRB-
cord-341690-h8fqijk5	331	14	Vazyme	Vazyme	NNP
cord-341690-h8fqijk5	331	15	)	)	-RRB-
cord-341690-h8fqijk5	331	16	according	accord	VBG
cord-341690-h8fqijk5	331	17	to	to	IN
cord-341690-h8fqijk5	331	18	the	the	DT
cord-341690-h8fqijk5	331	19	manufacturer	manufacturer	NN
cord-341690-h8fqijk5	331	20	's	's	POS
cord-341690-h8fqijk5	331	21	instructions	instruction	NNS
cord-341690-h8fqijk5	331	22	.	.	.
cord-341690-h8fqijk5	332	1	All	all	DT
cord-341690-h8fqijk5	332	2	constructs	construct	NNS
cord-341690-h8fqijk5	332	3	were	be	VBD
cord-341690-h8fqijk5	332	4	verified	verify	VBN
cord-341690-h8fqijk5	332	5	by	by	IN
cord-341690-h8fqijk5	332	6	DNA	dna	NN
cord-341690-h8fqijk5	332	7	sequencing	sequencing	NN
cord-341690-h8fqijk5	332	8	.	.	.
cord-341690-h8fqijk5	333	1	The	the	DT
cord-341690-h8fqijk5	333	2	primers	primer	NNS
cord-341690-h8fqijk5	333	3	used	use	VBN
cord-341690-h8fqijk5	333	4	in	in	IN
cord-341690-h8fqijk5	333	5	PCR	PCR	NNP
cord-341690-h8fqijk5	333	6	and	and	CC
cord-341690-h8fqijk5	333	7	for	for	IN
cord-341690-h8fqijk5	333	8	the	the	DT
cord-341690-h8fqijk5	333	9	site	site	NN
cord-341690-h8fqijk5	333	10	-	-	HYPH
cord-341690-h8fqijk5	333	11	directed	direct	VBN
cord-341690-h8fqijk5	333	12	mutagenesis	mutagenesis	NN
cord-341690-h8fqijk5	333	13	are	be	VBP
cord-341690-h8fqijk5	333	14	described	describe	VBN
cord-341690-h8fqijk5	333	15	in	in	IN
cord-341690-h8fqijk5	333	16	Supplemental	Supplemental	NNP
cord-341690-h8fqijk5	333	17	Tables	Tables	NNP
cord-341690-h8fqijk5	333	18	S3	S3	NNP
cord-341690-h8fqijk5	333	19	and	and	CC
cord-341690-h8fqijk5	333	20	S4	s4	NN
cord-341690-h8fqijk5	333	21	.	.	.
cord-341690-h8fqijk5	334	1	pLVX	plvx	LS
cord-341690-h8fqijk5	334	2	-	-	:
cord-341690-h8fqijk5	334	3	shRNA2	shRNA2	NNP
cord-341690-h8fqijk5	334	4	is	be	VBZ
cord-341690-h8fqijk5	334	5	an	an	DT
cord-341690-h8fqijk5	334	6	HIV-1-based	hiv-1-based	JJ
cord-341690-h8fqijk5	334	7	,	,	,
cord-341690-h8fqijk5	334	8	lentiviral	lentiviral	JJ
cord-341690-h8fqijk5	334	9	expression	expression	NN
cord-341690-h8fqijk5	334	10	vector	vector	NN
cord-341690-h8fqijk5	334	11	designed	design	VBN
cord-341690-h8fqijk5	334	12	to	to	TO
cord-341690-h8fqijk5	334	13	express	express	VB
cord-341690-h8fqijk5	334	14	a	a	DT
cord-341690-h8fqijk5	334	15	small	small	JJ
cord-341690-h8fqijk5	334	16	hairpin	hairpin	NN
cord-341690-h8fqijk5	334	17	RNA	RNA	NNP
cord-341690-h8fqijk5	334	18	(	(	-LRB-
cord-341690-h8fqijk5	334	19	shRNA	shrna	NN
cord-341690-h8fqijk5	334	20	)	)	-RRB-
cord-341690-h8fqijk5	334	21	for	for	IN
cord-341690-h8fqijk5	334	22	RNA	RNA	NNP
cord-341690-h8fqijk5	334	23	interference	interference	NN
cord-341690-h8fqijk5	334	24	(	(	-LRB-
cord-341690-h8fqijk5	334	25	RNAi	RNAi	NNP
cord-341690-h8fqijk5	334	26	)	)	-RRB-
cord-341690-h8fqijk5	334	27	studies	study	NNS
cord-341690-h8fqijk5	334	28	(	(	-LRB-
cord-341690-h8fqijk5	334	29	Clontech	Clontech	NNP
cord-341690-h8fqijk5	334	30	)	)	-RRB-
cord-341690-h8fqijk5	334	31	.	.	.
cord-341690-h8fqijk5	335	1	The	the	DT
cord-341690-h8fqijk5	335	2	best	good	JJS
cord-341690-h8fqijk5	335	3	silencing	silencing	NN
cord-341690-h8fqijk5	335	4	efficiency	efficiency	NN
cord-341690-h8fqijk5	335	5	was	be	VBD
cord-341690-h8fqijk5	335	6	observed	observe	VBN
cord-341690-h8fqijk5	335	7	with	with	IN
cord-341690-h8fqijk5	335	8	clone	clone	NN
cord-341690-h8fqijk5	335	9	NM_001004043	NM_001004043	NNP
cord-341690-h8fqijk5	335	10	(	(	-LRB-
cord-341690-h8fqijk5	335	11	porcine	porcine	JJ
cord-341690-h8fqijk5	335	12	cofilin	cofilin	NN
cord-341690-h8fqijk5	335	13	)	)	-RRB-
cord-341690-h8fqijk5	335	14	and	and	CC
cord-341690-h8fqijk5	335	15	NM_214007	NM_214007	NNP
cord-341690-h8fqijk5	335	16	(	(	-LRB-
cord-341690-h8fqijk5	335	17	porcine	porcine	JJ
cord-341690-h8fqijk5	335	18	EGFR	EGFR	NNP
cord-341690-h8fqijk5	335	19	)	)	-RRB-
cord-341690-h8fqijk5	335	20	.	.	.
cord-341690-h8fqijk5	336	1	Targeting	targeting	NN
cord-341690-h8fqijk5	336	2	sequences	sequence	NNS
cord-341690-h8fqijk5	336	3	are	be	VBP
cord-341690-h8fqijk5	336	4	described	describe	VBN
cord-341690-h8fqijk5	336	5	in	in	IN
cord-341690-h8fqijk5	336	6	Supplemental	supplemental	JJ
cord-341690-h8fqijk5	336	7	Table	Table	NNP
cord-341690-h8fqijk5	336	8	S5	S5	NNP
cord-341690-h8fqijk5	336	9	.	.	.
cord-341690-h8fqijk5	337	1	HEK293	HEK293	NNP
cord-341690-h8fqijk5	337	2	T	t	NN
cord-341690-h8fqijk5	337	3	cells	cell	NNS
cord-341690-h8fqijk5	337	4	were	be	VBD
cord-341690-h8fqijk5	337	5	transfected	transfecte	VBN
cord-341690-h8fqijk5	337	6	with	with	IN
cord-341690-h8fqijk5	337	7	1	1	CD
cord-341690-h8fqijk5	337	8	μg	μg	CD
cord-341690-h8fqijk5	337	9	of	of	IN
cord-341690-h8fqijk5	337	10	specific	specific	JJ
cord-341690-h8fqijk5	337	11	expression	expression	NN
cord-341690-h8fqijk5	337	12	plasmid	plasmid	NN
cord-341690-h8fqijk5	337	13	per	per	IN
cord-341690-h8fqijk5	337	14	10	10	CD
cord-341690-h8fqijk5	337	15	6	6	CD
cord-341690-h8fqijk5	337	16	cells	cell	NNS
cord-341690-h8fqijk5	337	17	using	use	VBG
cord-341690-h8fqijk5	337	18	the	the	DT
cord-341690-h8fqijk5	337	19	X	x	NN
cord-341690-h8fqijk5	337	20	-	-	NN
cord-341690-h8fqijk5	337	21	tremeGENE	tremeGENE	JJS
cord-341690-h8fqijk5	337	22	HP	HP	NNP
cord-341690-h8fqijk5	337	23	DNA	DNA	NNP
cord-341690-h8fqijk5	337	24	Transfection	Transfection	NNP
cord-341690-h8fqijk5	337	25	Reagent	Reagent	NNP
cord-341690-h8fqijk5	337	26	(	(	-LRB-
cord-341690-h8fqijk5	337	27	Roche	Roche	NNP
cord-341690-h8fqijk5	337	28	)	)	-RRB-
cord-341690-h8fqijk5	337	29	according	accord	VBG
cord-341690-h8fqijk5	337	30	to	to	IN
cord-341690-h8fqijk5	337	31	the	the	DT
cord-341690-h8fqijk5	337	32	manufacturer	manufacturer	NN
cord-341690-h8fqijk5	337	33	's	's	POS
cord-341690-h8fqijk5	337	34	instructions	instruction	NNS
cord-341690-h8fqijk5	337	35	,	,	,
cord-341690-h8fqijk5	337	36	with	with	IN
cord-341690-h8fqijk5	337	37	Opti	Opti	NNP
cord-341690-h8fqijk5	337	38	-	-	HYPH
cord-341690-h8fqijk5	337	39	MEM	MEM	NNP
cord-341690-h8fqijk5	337	40	(	(	-LRB-
cord-341690-h8fqijk5	337	41	Invitrogen	Invitrogen	NNP
cord-341690-h8fqijk5	337	42	)	)	-RRB-
cord-341690-h8fqijk5	337	43	included	include	VBD
cord-341690-h8fqijk5	337	44	in	in	IN
cord-341690-h8fqijk5	337	45	T-25	T-25	NNP
cord-341690-h8fqijk5	337	46	cell	cell	NN
cord-341690-h8fqijk5	337	47	culture	culture	NN
cord-341690-h8fqijk5	337	48	flask	flask	NN
cord-341690-h8fqijk5	337	49	.	.	.
cord-341690-h8fqijk5	338	1	Lentivial	lentivial	JJ
cord-341690-h8fqijk5	338	2	particles	particle	NNS
cord-341690-h8fqijk5	338	3	(	(	-LRB-
cord-341690-h8fqijk5	338	4	MOI	MOI	NNP
cord-341690-h8fqijk5	338	5	=	=	SYM
cord-341690-h8fqijk5	338	6	1	1	CD
cord-341690-h8fqijk5	338	7	)	)	-RRB-
cord-341690-h8fqijk5	338	8	were	be	VBD
cord-341690-h8fqijk5	338	9	added	add	VBN
cord-341690-h8fqijk5	338	10	to	to	IN
cord-341690-h8fqijk5	338	11	the	the	DT
cord-341690-h8fqijk5	338	12	IPEC	IPEC	NNP
cord-341690-h8fqijk5	338	13	-	-	HYPH
cord-341690-h8fqijk5	338	14	J2	j2	NN
cord-341690-h8fqijk5	338	15	cells	cell	NNS
cord-341690-h8fqijk5	338	16	,	,	,
cord-341690-h8fqijk5	338	17	and	and	CC
cord-341690-h8fqijk5	338	18	gently	gently	RB
cord-341690-h8fqijk5	338	19	mixed	mixed	JJ
cord-341690-h8fqijk5	338	20	.	.	.
cord-341690-h8fqijk5	339	1	IPEC	IPEC	NNP
cord-341690-h8fqijk5	339	2	-	-	HYPH
cord-341690-h8fqijk5	339	3	J2	j2	NN
cord-341690-h8fqijk5	339	4	cells	cell	NNS
cord-341690-h8fqijk5	339	5	were	be	VBD
cord-341690-h8fqijk5	339	6	cultivated	cultivate	VBN
cord-341690-h8fqijk5	339	7	on	on	IN
cord-341690-h8fqijk5	339	8	T-25	T-25	NNP
cord-341690-h8fqijk5	339	9	cell	cell	NN
cord-341690-h8fqijk5	339	10	culture	culture	NN
cord-341690-h8fqijk5	339	11	flask	flask	NN
cord-341690-h8fqijk5	339	12	and	and	CC
cord-341690-h8fqijk5	339	13	incubated	incubate	VBN
cord-341690-h8fqijk5	339	14	with	with	IN
cord-341690-h8fqijk5	339	15	TGEV	TGEV	NNP
cord-341690-h8fqijk5	339	16	at	at	IN
cord-341690-h8fqijk5	339	17	MOI	MOI	NNP
cord-341690-h8fqijk5	339	18	=	=	SYM
cord-341690-h8fqijk5	339	19	2	2	CD
cord-341690-h8fqijk5	339	20	for	for	IN
cord-341690-h8fqijk5	339	21	1h	1h	CD
cord-341690-h8fqijk5	339	22	at	at	IN
cord-341690-h8fqijk5	339	23	4	4	CD
cord-341690-h8fqijk5	339	24	°	°	NN
cord-341690-h8fqijk5	339	25	C	c	NN
cord-341690-h8fqijk5	339	26	,	,	,
cord-341690-h8fqijk5	339	27	then	then	RB
cord-341690-h8fqijk5	339	28	shifted	shift	VBD
cord-341690-h8fqijk5	339	29	to	to	IN
cord-341690-h8fqijk5	339	30	37	37	CD
cord-341690-h8fqijk5	339	31	℃	℃	NNS
cord-341690-h8fqijk5	339	32	for	for	IN
cord-341690-h8fqijk5	339	33	30	30	CD
cord-341690-h8fqijk5	339	34	min	min	NN
cord-341690-h8fqijk5	339	35	.	.	.
cord-341690-h8fqijk5	340	1	Samples	sample	NNS
cord-341690-h8fqijk5	340	2	were	be	VBD
cord-341690-h8fqijk5	340	3	fixed	fix	VBN
cord-341690-h8fqijk5	340	4	in	in	IN
cord-341690-h8fqijk5	340	5	a	a	DT
cord-341690-h8fqijk5	340	6	2.5	2.5	CD
cord-341690-h8fqijk5	340	7	%	%	NN
cord-341690-h8fqijk5	340	8	glutaraldehyde	glutaraldehyde	NN
cord-341690-h8fqijk5	340	9	solution	solution	NN
cord-341690-h8fqijk5	340	10	in	in	IN
cord-341690-h8fqijk5	340	11	PBS	PBS	NNP
cord-341690-h8fqijk5	340	12	for	for	IN
cord-341690-h8fqijk5	340	13	24h	24h	NNS
cord-341690-h8fqijk5	340	14	.	.	.
cord-341690-h8fqijk5	341	1	After	after	IN
cord-341690-h8fqijk5	341	2	fixation	fixation	NN
cord-341690-h8fqijk5	341	3	,	,	,
cord-341690-h8fqijk5	341	4	the	the	DT
cord-341690-h8fqijk5	341	5	monolayer	monolayer	NN
cord-341690-h8fqijk5	341	6	was	be	VBD
cord-341690-h8fqijk5	341	7	gently	gently	RB
cord-341690-h8fqijk5	341	8	removed	remove	VBN
cord-341690-h8fqijk5	341	9	from	from	IN
cord-341690-h8fqijk5	341	10	the	the	DT
cord-341690-h8fqijk5	341	11	flask	flask	NN
cord-341690-h8fqijk5	341	12	with	with	IN
cord-341690-h8fqijk5	341	13	a	a	DT
cord-341690-h8fqijk5	341	14	rubber	rubber	NN
cord-341690-h8fqijk5	341	15	policeman	policeman	NN
cord-341690-h8fqijk5	341	16	and	and	CC
cord-341690-h8fqijk5	341	17	the	the	DT
cord-341690-h8fqijk5	341	18	cell	cell	NN
cord-341690-h8fqijk5	341	19	suspension	suspension	NN
cord-341690-h8fqijk5	341	20	was	be	VBD
cord-341690-h8fqijk5	341	21	pelleted	pellete	VBN
cord-341690-h8fqijk5	341	22	by	by	IN
cord-341690-h8fqijk5	341	23	low	low	JJ
cord-341690-h8fqijk5	341	24	speed	speed	NN
cord-341690-h8fqijk5	341	25	centrifugation	centrifugation	NN
cord-341690-h8fqijk5	341	26	(	(	-LRB-
cord-341690-h8fqijk5	341	27	2500×g	2500×g	CD
cord-341690-h8fqijk5	341	28	for	for	IN
cord-341690-h8fqijk5	341	29	5min	5min	CD
cord-341690-h8fqijk5	341	30	)	)	-RRB-
cord-341690-h8fqijk5	341	31	.	.	.
cord-341690-h8fqijk5	342	1	The	the	DT
cord-341690-h8fqijk5	342	2	cells	cell	NNS
cord-341690-h8fqijk5	342	3	were	be	VBD
cord-341690-h8fqijk5	342	4	then	then	RB
cord-341690-h8fqijk5	342	5	washed	wash	VBN
cord-341690-h8fqijk5	342	6	twice	twice	RB
cord-341690-h8fqijk5	342	7	by	by	IN
cord-341690-h8fqijk5	342	8	centrifugation	centrifugation	NN
cord-341690-h8fqijk5	342	9	in	in	IN
cord-341690-h8fqijk5	342	10	0.1	0.1	CD
cord-341690-h8fqijk5	342	11	M	M	NNP
cord-341690-h8fqijk5	342	12	PBS	PBS	NNP
cord-341690-h8fqijk5	342	13	.	.	.
cord-341690-h8fqijk5	343	1	The	the	DT
cord-341690-h8fqijk5	343	2	pellet	pellet	NN
cord-341690-h8fqijk5	343	3	of	of	IN
cord-341690-h8fqijk5	343	4	cells	cell	NNS
cord-341690-h8fqijk5	343	5	was	be	VBD
cord-341690-h8fqijk5	343	6	then	then	RB
cord-341690-h8fqijk5	343	7	fixed	fix	VBN
cord-341690-h8fqijk5	343	8	overnight	overnight	RB
cord-341690-h8fqijk5	343	9	at	at	IN
cord-341690-h8fqijk5	343	10	4	4	CD
cord-341690-h8fqijk5	343	11	℃	℃	NNS
cord-341690-h8fqijk5	343	12	and	and	CC
cord-341690-h8fqijk5	343	13	then	then	RB
cord-341690-h8fqijk5	343	14	prepared	prepare	VBD
cord-341690-h8fqijk5	343	15	for	for	IN
cord-341690-h8fqijk5	343	16	transmission	transmission	NN
cord-341690-h8fqijk5	343	17	electron	electron	NN
cord-341690-h8fqijk5	343	18	microscope	microscope	NN
cord-341690-h8fqijk5	343	19	(	(	-LRB-
cord-341690-h8fqijk5	343	20	TEM	TEM	NNP
cord-341690-h8fqijk5	343	21	)	)	-RRB-
cord-341690-h8fqijk5	343	22	as	as	IN
cord-341690-h8fqijk5	343	23	described	describe	VBN
cord-341690-h8fqijk5	343	24	[	[	-LRB-
cord-341690-h8fqijk5	343	25	51	51	CD
cord-341690-h8fqijk5	343	26	]	]	-RRB-
cord-341690-h8fqijk5	343	27	.	.	.
cord-341690-h8fqijk5	344	1	Samples	sample	NNS
cord-341690-h8fqijk5	344	2	were	be	VBD
cord-341690-h8fqijk5	344	3	visualized	visualize	VBN
cord-341690-h8fqijk5	344	4	using	use	VBG
cord-341690-h8fqijk5	344	5	a	a	DT
cord-341690-h8fqijk5	344	6	Hitachi-7650	Hitachi-7650	NNP
cord-341690-h8fqijk5	344	7	transmission	transmission	NN
cord-341690-h8fqijk5	344	8	electron	electron	NN
cord-341690-h8fqijk5	344	9	microscope	microscope	NN
cord-341690-h8fqijk5	344	10	(	(	-LRB-
cord-341690-h8fqijk5	344	11	TEM	TEM	NNP
cord-341690-h8fqijk5	344	12	,	,	,
cord-341690-h8fqijk5	344	13	Japan	Japan	NNP
cord-341690-h8fqijk5	344	14	)	)	-RRB-
cord-341690-h8fqijk5	344	15	at	at	IN
cord-341690-h8fqijk5	344	16	120	120	CD
cord-341690-h8fqijk5	344	17	kV.	kv.	JJ
cord-341690-h8fqijk5	344	18	IPEC	IPEC	NNP
cord-341690-h8fqijk5	344	19	-	-	HYPH
cord-341690-h8fqijk5	344	20	J2	j2	NN
cord-341690-h8fqijk5	344	21	cells	cell	NNS
cord-341690-h8fqijk5	344	22	were	be	VBD
cord-341690-h8fqijk5	344	23	grown	grow	VBN
cord-341690-h8fqijk5	344	24	on	on	IN
cord-341690-h8fqijk5	344	25	coverslips	coverslip	NNS
cord-341690-h8fqijk5	344	26	in	in	IN
cord-341690-h8fqijk5	344	27	24-well	24-well	CD
cord-341690-h8fqijk5	344	28	tissue	tissue	NN
cord-341690-h8fqijk5	344	29	culture	culture	NN
cord-341690-h8fqijk5	344	30	plates	plate	NNS
cord-341690-h8fqijk5	344	31	and	and	CC
cord-341690-h8fqijk5	344	32	incubated	incubate	VBN
cord-341690-h8fqijk5	344	33	with	with	IN
cord-341690-h8fqijk5	344	34	TGEV	TGEV	NNS
cord-341690-h8fqijk5	344	35	at	at	IN
cord-341690-h8fqijk5	344	36	MOI=2	MOI=2	NNP
cord-341690-h8fqijk5	344	37	for	for	IN
cord-341690-h8fqijk5	344	38	1	1	CD
cord-341690-h8fqijk5	344	39	h	h	NN
cord-341690-h8fqijk5	344	40	at	at	IN
cord-341690-h8fqijk5	344	41	4	4	CD
cord-341690-h8fqijk5	344	42	°	°	NN
cord-341690-h8fqijk5	344	43	C	c	NN
cord-341690-h8fqijk5	344	44	,	,	,
cord-341690-h8fqijk5	344	45	then	then	RB
cord-341690-h8fqijk5	344	46	shifted	shift	VBD
cord-341690-h8fqijk5	344	47	to	to	IN
cord-341690-h8fqijk5	344	48	37	37	CD
cord-341690-h8fqijk5	344	49	°	°	NN
cord-341690-h8fqijk5	344	50	C	c	NN
cord-341690-h8fqijk5	344	51	.	.	.
cord-341690-h8fqijk5	345	1	At	at	IN
cord-341690-h8fqijk5	345	2	the	the	DT
cord-341690-h8fqijk5	345	3	indicated	indicate	VBN
cord-341690-h8fqijk5	345	4	time	time	NN
cord-341690-h8fqijk5	345	5	points	point	NNS
cord-341690-h8fqijk5	345	6	,	,	,
cord-341690-h8fqijk5	345	7	cells	cell	NNS
cord-341690-h8fqijk5	345	8	were	be	VBD
cord-341690-h8fqijk5	345	9	fixed	fix	VBN
cord-341690-h8fqijk5	345	10	in	in	IN
cord-341690-h8fqijk5	345	11	4	4	CD
cord-341690-h8fqijk5	345	12	%	%	NN
cord-341690-h8fqijk5	345	13	paraformaldehyde	paraformaldehyde	NNP
cord-341690-h8fqijk5	345	14	for	for	IN
cord-341690-h8fqijk5	345	15	15	15	CD
cord-341690-h8fqijk5	345	16	min	min	NN
cord-341690-h8fqijk5	345	17	then	then	RB
cord-341690-h8fqijk5	345	18	permeabilised	permeabilise	VBD
cord-341690-h8fqijk5	345	19	with	with	IN
cord-341690-h8fqijk5	345	20	0.1	0.1	CD
cord-341690-h8fqijk5	345	21	%	%	NN
cord-341690-h8fqijk5	345	22	Triton	Triton	NNP
cord-341690-h8fqijk5	345	23	X-100	x-100	RB
cord-341690-h8fqijk5	345	24	for	for	IN
cord-341690-h8fqijk5	345	25	5	5	CD
cord-341690-h8fqijk5	345	26	min	min	NN
cord-341690-h8fqijk5	345	27	.	.	.
cord-341690-h8fqijk5	346	1	Samples	sample	NNS
cord-341690-h8fqijk5	346	2	were	be	VBD
cord-341690-h8fqijk5	346	3	blocked	block	VBN
cord-341690-h8fqijk5	346	4	in	in	IN
cord-341690-h8fqijk5	346	5	5	5	CD
cord-341690-h8fqijk5	346	6	%	%	NN
cord-341690-h8fqijk5	346	7	bovine	bovine	JJ
cord-341690-h8fqijk5	346	8	serum	serum	NN
cord-341690-h8fqijk5	346	9	albumin	albumin	NN
cord-341690-h8fqijk5	346	10	(	(	-LRB-
cord-341690-h8fqijk5	346	11	BSA	BSA	NNP
cord-341690-h8fqijk5	346	12	)	)	-RRB-
cord-341690-h8fqijk5	346	13	for	for	IN
cord-341690-h8fqijk5	346	14	20	20	CD
cord-341690-h8fqijk5	346	15	min	min	NN
cord-341690-h8fqijk5	346	16	and	and	CC
cord-341690-h8fqijk5	346	17	incubated	incubate	VBN
cord-341690-h8fqijk5	346	18	with	with	IN
cord-341690-h8fqijk5	346	19	primary	primary	JJ
cord-341690-h8fqijk5	346	20	antibodies	antibody	NNS
cord-341690-h8fqijk5	346	21	(	(	-LRB-
cord-341690-h8fqijk5	346	22	1:1000	1:1000	NNS
cord-341690-h8fqijk5	346	23	for	for	IN
cord-341690-h8fqijk5	346	24	the	the	DT
cord-341690-h8fqijk5	346	25	Cell	Cell	NNP
cord-341690-h8fqijk5	346	26	Signaling	Signaling	NNP
cord-341690-h8fqijk5	346	27	Technology	Technology	NNP
cord-341690-h8fqijk5	346	28	antibody	antibody	NN
cord-341690-h8fqijk5	346	29	and	and	CC
cord-341690-h8fqijk5	346	30	Santa	Santa	NNP
cord-341690-h8fqijk5	346	31	Cruz	Cruz	NNP
cord-341690-h8fqijk5	346	32	antibody	antibody	NN
cord-341690-h8fqijk5	346	33	)	)	-RRB-
cord-341690-h8fqijk5	346	34	at	at	IN
cord-341690-h8fqijk5	346	35	4	4	CD
cord-341690-h8fqijk5	346	36	°	°	NN
cord-341690-h8fqijk5	346	37	C	c	NN
cord-341690-h8fqijk5	346	38	overnight	overnight	RB
cord-341690-h8fqijk5	346	39	then	then	RB
cord-341690-h8fqijk5	346	40	incubated	incubate	VBD
cord-341690-h8fqijk5	346	41	with	with	IN
cord-341690-h8fqijk5	346	42	fluorochrome	fluorochrome	RB
cord-341690-h8fqijk5	346	43	-	-	HYPH
cord-341690-h8fqijk5	346	44	conjugated	conjugate	VBN
cord-341690-h8fqijk5	346	45	secondary	secondary	JJ
cord-341690-h8fqijk5	346	46	antibodies	antibody	NNS
cord-341690-h8fqijk5	346	47	(	(	-LRB-
cord-341690-h8fqijk5	346	48	1:500	1:500	CD
cord-341690-h8fqijk5	346	49	)	)	-RRB-
cord-341690-h8fqijk5	346	50	at	at	IN
cord-341690-h8fqijk5	346	51	room	room	NN
cord-341690-h8fqijk5	346	52	temperature	temperature	NN
cord-341690-h8fqijk5	346	53	for	for	IN
cord-341690-h8fqijk5	346	54	1	1	CD
cord-341690-h8fqijk5	346	55	h.	h.	NN
cord-341690-h8fqijk5	347	1	To	to	TO
cord-341690-h8fqijk5	347	2	stain	stain	VB
cord-341690-h8fqijk5	347	3	F	F	NNP
cord-341690-h8fqijk5	347	4	-	-	HYPH
cord-341690-h8fqijk5	347	5	actin	actin	NNP
cord-341690-h8fqijk5	347	6	,	,	,
cord-341690-h8fqijk5	347	7	phalloidin	phalloidin	NNP
cord-341690-h8fqijk5	347	8	-	-	HYPH
cord-341690-h8fqijk5	347	9	TRITC	TRITC	NNP
cord-341690-h8fqijk5	348	1	(	(	-LRB-
cord-341690-h8fqijk5	348	2	Green	Green	NNP
cord-341690-h8fqijk5	348	3	,	,	,
cord-341690-h8fqijk5	348	4	Red	Red	NNP
cord-341690-h8fqijk5	348	5	)	)	-RRB-
cord-341690-h8fqijk5	348	6	(	(	-LRB-
cord-341690-h8fqijk5	348	7	Life	life	NN
cord-341690-h8fqijk5	348	8	)	)	-RRB-
cord-341690-h8fqijk5	348	9	was	be	VBD
cord-341690-h8fqijk5	348	10	added	add	VBN
cord-341690-h8fqijk5	348	11	for	for	IN
cord-341690-h8fqijk5	348	12	20	20	CD
cord-341690-h8fqijk5	348	13	min	min	NN
cord-341690-h8fqijk5	348	14	at	at	IN
cord-341690-h8fqijk5	348	15	room	room	NN
cord-341690-h8fqijk5	348	16	temperature	temperature	NN
cord-341690-h8fqijk5	348	17	.	.	.
cord-341690-h8fqijk5	349	1	Nuclei	nucleus	NNS
cord-341690-h8fqijk5	349	2	were	be	VBD
cord-341690-h8fqijk5	349	3	stained	stain	VBN
cord-341690-h8fqijk5	349	4	using	use	VBG
cord-341690-h8fqijk5	349	5	1	1	CD
cord-341690-h8fqijk5	349	6	ug	ug	NNP
cord-341690-h8fqijk5	349	7	/	/	SYM
cord-341690-h8fqijk5	349	8	ml	ml	NN
cord-341690-h8fqijk5	349	9	DAPI	DAPI	NNP
cord-341690-h8fqijk5	349	10	(	(	-LRB-
cord-341690-h8fqijk5	349	11	4',6'diamidino-2-phenylindole	4',6'diamidino-2-phenylindole	CD
cord-341690-h8fqijk5	349	12	dihydrochloride)-PBS	dihydrochloride)-pb	NNS
cord-341690-h8fqijk5	349	13	for	for	IN
cord-341690-h8fqijk5	349	14	5	5	CD
cord-341690-h8fqijk5	349	15	min	min	NN
cord-341690-h8fqijk5	349	16	at	at	IN
cord-341690-h8fqijk5	349	17	room	room	NN
cord-341690-h8fqijk5	349	18	temperature	temperature	NN
cord-341690-h8fqijk5	349	19	.	.	.
cord-341690-h8fqijk5	350	1	Images	image	NNS
cord-341690-h8fqijk5	350	2	were	be	VBD
cord-341690-h8fqijk5	350	3	captured	capture	VBN
cord-341690-h8fqijk5	350	4	with	with	IN
cord-341690-h8fqijk5	350	5	a	a	DT
cord-341690-h8fqijk5	350	6	Zeiss	Zeiss	NNP
cord-341690-h8fqijk5	350	7	LSM710	LSM710	NNP
cord-341690-h8fqijk5	350	8	confocal	confocal	JJ
cord-341690-h8fqijk5	350	9	laser	laser	NN
cord-341690-h8fqijk5	350	10	-	-	HYPH
cord-341690-h8fqijk5	350	11	scanning	scan	VBG
cord-341690-h8fqijk5	350	12	microscopy	microscopy	NN
cord-341690-h8fqijk5	350	13	system	system	NN
cord-341690-h8fqijk5	350	14	and	and	CC
cord-341690-h8fqijk5	350	15	a	a	DT
cord-341690-h8fqijk5	350	16	40x	40x	CD
cord-341690-h8fqijk5	350	17	objective	objective	JJ
cord-341690-h8fqijk5	350	18	lens	lens	NN
cord-341690-h8fqijk5	350	19	.	.	.
cord-341690-h8fqijk5	351	1	Top	top	JJ
cord-341690-h8fqijk5	351	2	view	view	NN
cord-341690-h8fqijk5	351	3	images	image	NNS
cord-341690-h8fqijk5	351	4	were	be	VBD
cord-341690-h8fqijk5	351	5	prepared	prepare	VBN
cord-341690-h8fqijk5	351	6	as	as	IN
cord-341690-h8fqijk5	351	7	compacted	compact	VBN
cord-341690-h8fqijk5	351	8	Z	Z	NNP
cord-341690-h8fqijk5	351	9	-	-	HYPH
cord-341690-h8fqijk5	351	10	Stack	stack	NN
cord-341690-h8fqijk5	351	11	images	image	NNS
cord-341690-h8fqijk5	351	12	of	of	IN
cord-341690-h8fqijk5	351	13	non	non	JJ
cord-341690-h8fqijk5	351	14	-	-	JJ
cord-341690-h8fqijk5	351	15	permeabilised	permeabilised	JJ
cord-341690-h8fqijk5	351	16	cells	cell	NNS
cord-341690-h8fqijk5	351	17	,	,	,
cord-341690-h8fqijk5	351	18	using	use	VBG
cord-341690-h8fqijk5	351	19	ZEN	ZEN	NNP
cord-341690-h8fqijk5	351	20	2012	2012	CD
cord-341690-h8fqijk5	351	21	(	(	-LRB-
cord-341690-h8fqijk5	351	22	Zeiss	Zeiss	NNP
cord-341690-h8fqijk5	351	23	)	)	-RRB-
cord-341690-h8fqijk5	351	24	software	software	NN
cord-341690-h8fqijk5	351	25	.	.	.
cord-341690-h8fqijk5	352	1	The	the	DT
cord-341690-h8fqijk5	352	2	co	co	NN
cord-341690-h8fqijk5	352	3	-	-	NN
cord-341690-h8fqijk5	352	4	localization	localization	NN
cord-341690-h8fqijk5	352	5	of	of	IN
cord-341690-h8fqijk5	352	6	two	two	CD
cord-341690-h8fqijk5	352	7	channels	channel	NNS
cord-341690-h8fqijk5	352	8	was	be	VBD
cord-341690-h8fqijk5	352	9	detected	detect	VBN
cord-341690-h8fqijk5	352	10	using	use	VBG
cord-341690-h8fqijk5	352	11	the	the	DT
cord-341690-h8fqijk5	352	12	co	co	NN
cord-341690-h8fqijk5	352	13	-	-	NN
cord-341690-h8fqijk5	352	14	localization	localization	JJ
cord-341690-h8fqijk5	352	15	finder	finder	NN
cord-341690-h8fqijk5	352	16	plug	plug	NN
cord-341690-h8fqijk5	352	17	-	-	HYPH
cord-341690-h8fqijk5	352	18	in	in	NN
cord-341690-h8fqijk5	352	19	.	.	.
cord-341690-h8fqijk5	353	1	X	X	NNP
cord-341690-h8fqijk5	353	2	-	-	HYPH
cord-341690-h8fqijk5	353	3	y	y	NNP
cord-341690-h8fqijk5	353	4	plane	plane	NN
cord-341690-h8fqijk5	353	5	and	and	CC
cord-341690-h8fqijk5	353	6	z	z	NN
cord-341690-h8fqijk5	353	7	-	-	HYPH
cord-341690-h8fqijk5	353	8	axis	axis	NN
cord-341690-h8fqijk5	353	9	views	view	NNS
cord-341690-h8fqijk5	353	10	of	of	IN
cord-341690-h8fqijk5	353	11	confocal	confocal	JJ
cord-341690-h8fqijk5	353	12	images	image	NNS
cord-341690-h8fqijk5	353	13	were	be	VBD
cord-341690-h8fqijk5	353	14	prepared	prepare	VBN
cord-341690-h8fqijk5	353	15	using	use	VBG
cord-341690-h8fqijk5	353	16	ZEN	ZEN	NNP
cord-341690-h8fqijk5	353	17	2012	2012	CD
cord-341690-h8fqijk5	353	18	LE	LE	NNP
cord-341690-h8fqijk5	353	19	software	software	NN
cord-341690-h8fqijk5	353	20	from	from	IN
cord-341690-h8fqijk5	353	21	Zeiss	Zeiss	NNP
cord-341690-h8fqijk5	353	22	,	,	,
cord-341690-h8fqijk5	353	23	Germany	Germany	NNP
cord-341690-h8fqijk5	353	24	.	.	.
cord-341690-h8fqijk5	354	1	For	for	IN
cord-341690-h8fqijk5	354	2	viral	viral	JJ
cord-341690-h8fqijk5	354	3	labeling	labeling	NN
cord-341690-h8fqijk5	354	4	,	,	,
cord-341690-h8fqijk5	354	5	viruses	virus	NNS
cord-341690-h8fqijk5	354	6	were	be	VBD
cord-341690-h8fqijk5	354	7	filtered	filter	VBN
cord-341690-h8fqijk5	354	8	with	with	IN
cord-341690-h8fqijk5	354	9	0.22μm	0.22μm	CD
cord-341690-h8fqijk5	354	10	filter	filter	NN
cord-341690-h8fqijk5	354	11	,	,	,
cord-341690-h8fqijk5	354	12	and	and	CC
cord-341690-h8fqijk5	354	13	then	then	RB
cord-341690-h8fqijk5	354	14	clarified	clarify	VBN
cord-341690-h8fqijk5	354	15	by	by	IN
cord-341690-h8fqijk5	354	16	centrifugation	centrifugation	NN
cord-341690-h8fqijk5	354	17	at	at	IN
cord-341690-h8fqijk5	354	18	10,000×g	10,000×g	CD
cord-341690-h8fqijk5	354	19	for	for	IN
cord-341690-h8fqijk5	354	20	2.5	2.5	CD
cord-341690-h8fqijk5	354	21	h	h	NN
cord-341690-h8fqijk5	354	22	,	,	,
cord-341690-h8fqijk5	354	23	followed	follow	VBN
cord-341690-h8fqijk5	354	24	by	by	IN
cord-341690-h8fqijk5	354	25	ultra	ultra	JJ
cord-341690-h8fqijk5	354	26	-	-	JJ
cord-341690-h8fqijk5	354	27	centrifugation	centrifugation	JJ
cord-341690-h8fqijk5	354	28	using	use	VBG
cord-341690-h8fqijk5	354	29	20	20	CD
cord-341690-h8fqijk5	354	30	%	%	NN
cord-341690-h8fqijk5	354	31	,	,	,
cord-341690-h8fqijk5	354	32	40	40	CD
cord-341690-h8fqijk5	354	33	%	%	NN
cord-341690-h8fqijk5	354	34	,	,	,
cord-341690-h8fqijk5	354	35	60	60	CD
cord-341690-h8fqijk5	354	36	%	%	NN
cord-341690-h8fqijk5	354	37	sucrose	sucrose	NN
cord-341690-h8fqijk5	354	38	gradient	gradient	NN
cord-341690-h8fqijk5	354	39	at	at	IN
cord-341690-h8fqijk5	354	40	10,000×g	10,000×g	CD
cord-341690-h8fqijk5	354	41	for	for	IN
cord-341690-h8fqijk5	354	42	2.5	2.5	CD
cord-341690-h8fqijk5	354	43	h	h	NN
cord-341690-h8fqijk5	354	44	,	,	,
cord-341690-h8fqijk5	354	45	viruses	virus	NNS
cord-341690-h8fqijk5	354	46	were	be	VBD
cord-341690-h8fqijk5	354	47	labeled	label	VBN
cord-341690-h8fqijk5	354	48	with	with	IN
cord-341690-h8fqijk5	354	49	the	the	DT
cord-341690-h8fqijk5	354	50	fluorescent	fluorescent	NN
cord-341690-h8fqijk5	354	51	probe	probe	NN
cord-341690-h8fqijk5	354	52	DyLight	DyLight	NNP
cord-341690-h8fqijk5	354	53	594	594	CD
cord-341690-h8fqijk5	354	54	NHS	NHS	NNP
cord-341690-h8fqijk5	354	55	Ester	Ester	NNP
cord-341690-h8fqijk5	354	56	(	(	-LRB-
cord-341690-h8fqijk5	354	57	Thermo	Thermo	NNP
cord-341690-h8fqijk5	354	58	Scientific	Scientific	NNP
cord-341690-h8fqijk5	354	59	)	)	-RRB-
cord-341690-h8fqijk5	354	60	according	accord	VBG
cord-341690-h8fqijk5	354	61	to	to	IN
cord-341690-h8fqijk5	354	62	the	the	DT
cord-341690-h8fqijk5	354	63	manufacturer	manufacturer	NN
cord-341690-h8fqijk5	354	64	's	's	POS
cord-341690-h8fqijk5	354	65	instruction	instruction	NN
cord-341690-h8fqijk5	354	66	.	.	.
cord-341690-h8fqijk5	355	1	Unincorporated	unincorporated	JJ
cord-341690-h8fqijk5	355	2	dye	dye	NN
cord-341690-h8fqijk5	355	3	was	be	VBD
cord-341690-h8fqijk5	355	4	removed	remove	VBN
cord-341690-h8fqijk5	355	5	by	by	IN
cord-341690-h8fqijk5	355	6	using	use	VBG
cord-341690-h8fqijk5	355	7	commercial	commercial	JJ
cord-341690-h8fqijk5	355	8	fluorescent	fluorescent	JJ
cord-341690-h8fqijk5	355	9	dye	dye	NN
cord-341690-h8fqijk5	355	10	removal	removal	NN
cord-341690-h8fqijk5	355	11	columns	column	NNS
cord-341690-h8fqijk5	355	12	(	(	-LRB-
cord-341690-h8fqijk5	355	13	Thermo	Thermo	NNP
cord-341690-h8fqijk5	355	14	Scientific	Scientific	NNP
cord-341690-h8fqijk5	355	15	)	)	-RRB-
cord-341690-h8fqijk5	355	16	.	.	.
cord-341690-h8fqijk5	356	1	To	to	TO
cord-341690-h8fqijk5	356	2	observe	observe	VB
cord-341690-h8fqijk5	356	3	the	the	DT
cord-341690-h8fqijk5	356	4	clustering	clustering	NN
cord-341690-h8fqijk5	356	5	of	of	IN
cord-341690-h8fqijk5	356	6	lipid	lipid	NN
cord-341690-h8fqijk5	356	7	rafts	raft	NNS
cord-341690-h8fqijk5	356	8	in	in	IN
cord-341690-h8fqijk5	356	9	the	the	DT
cord-341690-h8fqijk5	356	10	cell	cell	NN
cord-341690-h8fqijk5	356	11	membrane	membrane	NN
cord-341690-h8fqijk5	356	12	,	,	,
cord-341690-h8fqijk5	356	13	IPEC	IPEC	NNP
cord-341690-h8fqijk5	356	14	-	-	HYPH
cord-341690-h8fqijk5	356	15	J2	j2	NN
cord-341690-h8fqijk5	356	16	cells	cell	NNS
cord-341690-h8fqijk5	356	17	were	be	VBD
cord-341690-h8fqijk5	356	18	incubated	incubate	VBN
cord-341690-h8fqijk5	356	19	with	with	IN
cord-341690-h8fqijk5	356	20	TGEV	TGEV	NNP
cord-341690-h8fqijk5	356	21	(	(	-LRB-
cord-341690-h8fqijk5	356	22	MOI	MOI	NNP
cord-341690-h8fqijk5	356	23	=	=	SYM
cord-341690-h8fqijk5	356	24	2	2	CD
cord-341690-h8fqijk5	356	25	)	)	-RRB-
cord-341690-h8fqijk5	356	26	or	or	CC
cord-341690-h8fqijk5	356	27	EGF	EGF	NNP
cord-341690-h8fqijk5	356	28	(	(	-LRB-
cord-341690-h8fqijk5	356	29	100	100	CD
cord-341690-h8fqijk5	356	30	ng	ng	NN
cord-341690-h8fqijk5	356	31	ml	ml	NN
cord-341690-h8fqijk5	356	32	-1	-1	NNP
cord-341690-h8fqijk5	356	33	)	)	-RRB-
cord-341690-h8fqijk5	356	34	,	,	,
cord-341690-h8fqijk5	356	35	or	or	CC
cord-341690-h8fqijk5	356	36	left	leave	VBD
cord-341690-h8fqijk5	356	37	untreated	untreated	JJ
cord-341690-h8fqijk5	356	38	at	at	IN
cord-341690-h8fqijk5	356	39	4	4	CD
cord-341690-h8fqijk5	356	40	°	°	NN
cord-341690-h8fqijk5	356	41	C	c	NN
cord-341690-h8fqijk5	356	42	for	for	IN
cord-341690-h8fqijk5	356	43	1	1	CD
cord-341690-h8fqijk5	356	44	h.	h.	NN
cord-341690-h8fqijk5	357	1	Subsequently	subsequently	RB
cord-341690-h8fqijk5	357	2	,	,	,
cord-341690-h8fqijk5	357	3	cells	cell	NNS
cord-341690-h8fqijk5	357	4	were	be	VBD
cord-341690-h8fqijk5	357	5	incubated	incubate	VBN
cord-341690-h8fqijk5	357	6	with	with	IN
cord-341690-h8fqijk5	357	7	FITCconjugated	fitcconjugated	JJ
cord-341690-h8fqijk5	357	8	cholera	cholera	NN
cord-341690-h8fqijk5	357	9	toxin	toxin	NN
cord-341690-h8fqijk5	357	10	beta	beta	NN
cord-341690-h8fqijk5	357	11	subunit	subunit	NN
cord-341690-h8fqijk5	357	12	(	(	-LRB-
cord-341690-h8fqijk5	357	13	CtxB	CtxB	NNP
cord-341690-h8fqijk5	357	14	)	)	-RRB-
cord-341690-h8fqijk5	357	15	(	(	-LRB-
cord-341690-h8fqijk5	357	16	30	30	CD
cord-341690-h8fqijk5	357	17	ug	ug	NNP
cord-341690-h8fqijk5	357	18	ml	ml	NNP
cord-341690-h8fqijk5	357	19	-1	-1	NNP
cord-341690-h8fqijk5	357	20	)	)	-RRB-
cord-341690-h8fqijk5	357	21	at	at	IN
cord-341690-h8fqijk5	357	22	4	4	CD
cord-341690-h8fqijk5	357	23	°	°	NN
cord-341690-h8fqijk5	357	24	C	c	NN
cord-341690-h8fqijk5	357	25	for	for	IN
cord-341690-h8fqijk5	357	26	1	1	CD
cord-341690-h8fqijk5	357	27	h	h	NN
cord-341690-h8fqijk5	357	28	and	and	CC
cord-341690-h8fqijk5	357	29	then	then	RB
cord-341690-h8fqijk5	357	30	incubated	incubate	VBD
cord-341690-h8fqijk5	357	31	at	at	IN
cord-341690-h8fqijk5	357	32	37	37	CD
cord-341690-h8fqijk5	357	33	°	°	NN
cord-341690-h8fqijk5	357	34	C	c	NN
cord-341690-h8fqijk5	357	35	for	for	IN
cord-341690-h8fqijk5	357	36	10	10	CD
cord-341690-h8fqijk5	357	37	min	min	NN
cord-341690-h8fqijk5	357	38	.	.	.
cord-341690-h8fqijk5	358	1	Cells	cell	NNS
cord-341690-h8fqijk5	358	2	were	be	VBD
cord-341690-h8fqijk5	358	3	fixed	fix	VBN
cord-341690-h8fqijk5	358	4	and	and	CC
cord-341690-h8fqijk5	358	5	observed	observe	VBN
cord-341690-h8fqijk5	358	6	by	by	IN
cord-341690-h8fqijk5	358	7	IF	if	NN
cord-341690-h8fqijk5	358	8	microscopy	microscopy	NNS
cord-341690-h8fqijk5	358	9	.	.	.
cord-341690-h8fqijk5	359	1	To	to	TO
cord-341690-h8fqijk5	359	2	observe	observe	VB
cord-341690-h8fqijk5	359	3	the	the	DT
cord-341690-h8fqijk5	359	4	co	co	NN
cord-341690-h8fqijk5	359	5	-	-	JJ
cord-341690-h8fqijk5	359	6	patching	patching	NN
cord-341690-h8fqijk5	359	7	of	of	IN
cord-341690-h8fqijk5	359	8	lipid	lipid	NN
cord-341690-h8fqijk5	359	9	rafts	raft	NNS
cord-341690-h8fqijk5	359	10	with	with	IN
cord-341690-h8fqijk5	359	11	proteins	protein	NNS
cord-341690-h8fqijk5	359	12	of	of	IN
cord-341690-h8fqijk5	359	13	interest	interest	NN
cord-341690-h8fqijk5	359	14	and	and	CC
cord-341690-h8fqijk5	359	15	for	for	IN
cord-341690-h8fqijk5	359	16	co	co	NN
cord-341690-h8fqijk5	359	17	-	-	NN
cord-341690-h8fqijk5	359	18	localization	localization	JJ
cord-341690-h8fqijk5	359	19	experiments	experiment	NNS
cord-341690-h8fqijk5	359	20	,	,	,
cord-341690-h8fqijk5	359	21	IPEC	IPEC	NNP
cord-341690-h8fqijk5	359	22	-	-	HYPH
cord-341690-h8fqijk5	359	23	J2	j2	NN
cord-341690-h8fqijk5	359	24	cells	cell	NNS
cord-341690-h8fqijk5	359	25	were	be	VBD
cord-341690-h8fqijk5	359	26	incubated	incubate	VBN
cord-341690-h8fqijk5	359	27	with	with	IN
cord-341690-h8fqijk5	359	28	TGEV	TGEV	NNP
cord-341690-h8fqijk5	359	29	(	(	-LRB-
cord-341690-h8fqijk5	359	30	MOI	MOI	NNP
cord-341690-h8fqijk5	359	31	=	=	SYM
cord-341690-h8fqijk5	359	32	2	2	CD
cord-341690-h8fqijk5	359	33	)	)	-RRB-
cord-341690-h8fqijk5	359	34	at	at	IN
cord-341690-h8fqijk5	359	35	4	4	CD
cord-341690-h8fqijk5	359	36	°	°	NN
cord-341690-h8fqijk5	359	37	C	c	NN
cord-341690-h8fqijk5	359	38	for	for	IN
cord-341690-h8fqijk5	359	39	1	1	CD
cord-341690-h8fqijk5	359	40	h	h	NN
cord-341690-h8fqijk5	359	41	,	,	,
cord-341690-h8fqijk5	359	42	and	and	CC
cord-341690-h8fqijk5	359	43	then	then	RB
cord-341690-h8fqijk5	359	44	incubated	incubate	VBD
cord-341690-h8fqijk5	359	45	with	with	IN
cord-341690-h8fqijk5	359	46	FITC	FITC	NNP
cord-341690-h8fqijk5	359	47	-	-	HYPH
cord-341690-h8fqijk5	359	48	CtxB	CtxB	NNP
cord-341690-h8fqijk5	359	49	at	at	IN
cord-341690-h8fqijk5	359	50	4	4	CD
cord-341690-h8fqijk5	359	51	°	°	NN
cord-341690-h8fqijk5	359	52	C	c	NN
cord-341690-h8fqijk5	359	53	for	for	IN
cord-341690-h8fqijk5	359	54	1	1	CD
cord-341690-h8fqijk5	359	55	h	h	NN
cord-341690-h8fqijk5	359	56	and	and	CC
cord-341690-h8fqijk5	359	57	at	at	IN
cord-341690-h8fqijk5	359	58	37	37	CD
cord-341690-h8fqijk5	359	59	°	°	NN
cord-341690-h8fqijk5	359	60	C	c	NN
cord-341690-h8fqijk5	359	61	for	for	IN
cord-341690-h8fqijk5	359	62	10	10	CD
cord-341690-h8fqijk5	359	63	min	min	NN
cord-341690-h8fqijk5	359	64	.	.	.
cord-341690-h8fqijk5	360	1	EGFR	EGFR	NNP
cord-341690-h8fqijk5	360	2	and	and	CC
cord-341690-h8fqijk5	360	3	TGEV	TGEV	NNP
cord-341690-h8fqijk5	360	4	were	be	VBD
cord-341690-h8fqijk5	360	5	visualized	visualize	VBN
cord-341690-h8fqijk5	360	6	by	by	IN
cord-341690-h8fqijk5	360	7	the	the	DT
cord-341690-h8fqijk5	360	8	common	common	JJ
cord-341690-h8fqijk5	360	9	immunofluorescence	immunofluorescence	NN
cord-341690-h8fqijk5	360	10	staining	staining	NN
cord-341690-h8fqijk5	360	11	protocol	protocol	NN
cord-341690-h8fqijk5	360	12	.	.	.
cord-341690-h8fqijk5	361	1	The	the	DT
cord-341690-h8fqijk5	361	2	cells	cell	NNS
cord-341690-h8fqijk5	361	3	were	be	VBD
cord-341690-h8fqijk5	361	4	fixed	fix	VBN
cord-341690-h8fqijk5	361	5	and	and	CC
cord-341690-h8fqijk5	361	6	stained	stain	VBN
cord-341690-h8fqijk5	361	7	with	with	IN
cord-341690-h8fqijk5	361	8	mouse	mouse	NN
cord-341690-h8fqijk5	361	9	anti	anti	JJ
cord-341690-h8fqijk5	361	10	-	-	JJ
cord-341690-h8fqijk5	361	11	TGEV	tgev	JJ
cord-341690-h8fqijk5	361	12	mAb	mAb	NNS
cord-341690-h8fqijk5	361	13	followed	follow	VBN
cord-341690-h8fqijk5	361	14	by	by	IN
cord-341690-h8fqijk5	361	15	DyLight	DyLight	NNP
cord-341690-h8fqijk5	361	16	594-conjugated	594-conjugated	CD
cord-341690-h8fqijk5	361	17	goat	goat	NNP
cord-341690-h8fqijk5	361	18	anti	anti	JJ
cord-341690-h8fqijk5	361	19	-	-	JJ
cord-341690-h8fqijk5	361	20	mouse	mouse	JJ
cord-341690-h8fqijk5	361	21	IgG	igg	NN
cord-341690-h8fqijk5	361	22	or	or	CC
cord-341690-h8fqijk5	362	1	rabbit	rabbit	NNP
cord-341690-h8fqijk5	362	2	anti	anti	NNP
cord-341690-h8fqijk5	362	3	-	-	JJ
cord-341690-h8fqijk5	362	4	p	p	JJ
cord-341690-h8fqijk5	362	5	-	-	HYPH
cord-341690-h8fqijk5	362	6	EGFR	egfr	NN
cord-341690-h8fqijk5	362	7	mAb	mAb	NNS
cord-341690-h8fqijk5	362	8	followed	follow	VBN
cord-341690-h8fqijk5	362	9	by	by	IN
cord-341690-h8fqijk5	362	10	DyLight	DyLight	NNP
cord-341690-h8fqijk5	362	11	594-conjugated	594-conjugated	CD
cord-341690-h8fqijk5	362	12	goat	goat	NNP
cord-341690-h8fqijk5	362	13	anti	anti	JJ
cord-341690-h8fqijk5	362	14	-	-	JJ
cord-341690-h8fqijk5	362	15	rabbit	rabbit	JJ
cord-341690-h8fqijk5	362	16	IgG.	IgG.	NNP
cord-341690-h8fqijk5	362	17	Cells	cell	NNS
cord-341690-h8fqijk5	362	18	were	be	VBD
cord-341690-h8fqijk5	362	19	examined	examine	VBN
cord-341690-h8fqijk5	362	20	by	by	IN
cord-341690-h8fqijk5	362	21	IF	if	NN
cord-341690-h8fqijk5	362	22	microscopy	microscopy	NNS
cord-341690-h8fqijk5	362	23	.	.	.
cord-341690-h8fqijk5	363	1	Cells	cell	NNS
cord-341690-h8fqijk5	363	2	were	be	VBD
cord-341690-h8fqijk5	363	3	lysed	lyse	VBN
cord-341690-h8fqijk5	363	4	in	in	IN
cord-341690-h8fqijk5	363	5	NP-40	NP-40	NNP
cord-341690-h8fqijk5	363	6	lysis	lysis	NN
cord-341690-h8fqijk5	363	7	buffer	buffer	NN
cord-341690-h8fqijk5	363	8	(	(	-LRB-
cord-341690-h8fqijk5	363	9	Beyotime	Beyotime	NNP
cord-341690-h8fqijk5	363	10	)	)	-RRB-
cord-341690-h8fqijk5	363	11	.	.	.
cord-341690-h8fqijk5	364	1	Protease	protease	JJ
cord-341690-h8fqijk5	364	2	inhibitor	inhibitor	NN
cord-341690-h8fqijk5	364	3	(	(	-LRB-
cord-341690-h8fqijk5	364	4	Thermo	Thermo	NNP
cord-341690-h8fqijk5	364	5	Scientific	Scientific	NNP
cord-341690-h8fqijk5	364	6	)	)	-RRB-
cord-341690-h8fqijk5	364	7	was	be	VBD
cord-341690-h8fqijk5	364	8	added	add	VBN
cord-341690-h8fqijk5	364	9	according	accord	VBG
cord-341690-h8fqijk5	364	10	to	to	IN
cord-341690-h8fqijk5	364	11	the	the	DT
cord-341690-h8fqijk5	364	12	manufacturer	manufacturer	NN
cord-341690-h8fqijk5	364	13	's	's	POS
cord-341690-h8fqijk5	364	14	instructions	instruction	NNS
cord-341690-h8fqijk5	364	15	.	.	.
cord-341690-h8fqijk5	365	1	After	after	IN
cord-341690-h8fqijk5	365	2	centrifugation	centrifugation	NN
cord-341690-h8fqijk5	365	3	at	at	IN
cord-341690-h8fqijk5	365	4	12000×g	12000×g	CD
cord-341690-h8fqijk5	365	5	for	for	IN
cord-341690-h8fqijk5	365	6	10	10	CD
cord-341690-h8fqijk5	365	7	min	min	NN
cord-341690-h8fqijk5	365	8	,	,	,
cord-341690-h8fqijk5	365	9	supernatant	supernatant	JJ
cord-341690-h8fqijk5	365	10	was	be	VBD
cord-341690-h8fqijk5	365	11	pretreated	pretreate	VBN
cord-341690-h8fqijk5	365	12	with	with	IN
cord-341690-h8fqijk5	365	13	protein	protein	NN
cord-341690-h8fqijk5	365	14	G	G	NNP
cord-341690-h8fqijk5	365	15	PLUS	PLUS	NNP
cord-341690-h8fqijk5	365	16	-	-	HYPH
cord-341690-h8fqijk5	365	17	Agarose	Agarose	NNP
cord-341690-h8fqijk5	365	18	(	(	-LRB-
cord-341690-h8fqijk5	365	19	Santa	Santa	NNP
cord-341690-h8fqijk5	365	20	Cruz	Cruz	NNP
cord-341690-h8fqijk5	365	21	)	)	-RRB-
cord-341690-h8fqijk5	365	22	and	and	CC
cord-341690-h8fqijk5	365	23	normal	normal	JJ
cord-341690-h8fqijk5	365	24	IgG	igg	NN
cord-341690-h8fqijk5	365	25	(	(	-LRB-
cord-341690-h8fqijk5	365	26	from	from	IN
cord-341690-h8fqijk5	365	27	the	the	DT
cord-341690-h8fqijk5	365	28	same	same	JJ
cord-341690-h8fqijk5	365	29	species	specie	NNS
cord-341690-h8fqijk5	365	30	as	as	IN
cord-341690-h8fqijk5	365	31	that	that	DT
cord-341690-h8fqijk5	365	32	of	of	IN
cord-341690-h8fqijk5	365	33	the	the	DT
cord-341690-h8fqijk5	365	34	immunoprecipitating	immunoprecipitate	VBG
cord-341690-h8fqijk5	365	35	antibody	antibody	NN
cord-341690-h8fqijk5	365	36	)	)	-RRB-
cord-341690-h8fqijk5	365	37	at	at	IN
cord-341690-h8fqijk5	365	38	4	4	CD
cord-341690-h8fqijk5	365	39	°	°	NN
cord-341690-h8fqijk5	365	40	C	c	NN
cord-341690-h8fqijk5	365	41	for	for	IN
cord-341690-h8fqijk5	365	42	1	1	CD
cord-341690-h8fqijk5	365	43	h	h	NN
cord-341690-h8fqijk5	365	44	to	to	TO
cord-341690-h8fqijk5	365	45	eliminate	eliminate	VB
cord-341690-h8fqijk5	365	46	nonspecific	nonspecific	JJ
cord-341690-h8fqijk5	365	47	binding	binding	NN
cord-341690-h8fqijk5	365	48	to	to	IN
cord-341690-h8fqijk5	365	49	the	the	DT
cord-341690-h8fqijk5	365	50	agarose	agarose	JJ
cord-341690-h8fqijk5	365	51	beads	bead	NNS
cord-341690-h8fqijk5	365	52	or	or	CC
cord-341690-h8fqijk5	366	1	IgG.	IgG.	NNP
cord-341690-h8fqijk5	367	1	The	the	DT
cord-341690-h8fqijk5	367	2	supernatant	supernatant	NN
cord-341690-h8fqijk5	367	3	was	be	VBD
cord-341690-h8fqijk5	367	4	incubated	incubate	VBN
cord-341690-h8fqijk5	367	5	with	with	IN
cord-341690-h8fqijk5	367	6	immunoprecipitation	immunoprecipitation	NN
cord-341690-h8fqijk5	367	7	antibody	antibody	NN
cord-341690-h8fqijk5	367	8	(	(	-LRB-
cord-341690-h8fqijk5	367	9	IP	IP	NNP
cord-341690-h8fqijk5	367	10	)	)	-RRB-
cord-341690-h8fqijk5	367	11	at	at	IN
cord-341690-h8fqijk5	367	12	4	4	CD
cord-341690-h8fqijk5	367	13	°	°	NN
cord-341690-h8fqijk5	367	14	C	c	NN
cord-341690-h8fqijk5	367	15	for	for	IN
cord-341690-h8fqijk5	367	16	8	8	CD
cord-341690-h8fqijk5	367	17	h	h	NN
cord-341690-h8fqijk5	367	18	and	and	CC
cord-341690-h8fqijk5	367	19	incubated	incubate	VBN
cord-341690-h8fqijk5	367	20	with	with	IN
cord-341690-h8fqijk5	367	21	fresh	fresh	JJ
cord-341690-h8fqijk5	367	22	agarose	agarose	JJ
cord-341690-h8fqijk5	367	23	beads	bead	NNS
cord-341690-h8fqijk5	367	24	at	at	IN
cord-341690-h8fqijk5	367	25	4	4	CD
cord-341690-h8fqijk5	367	26	°	°	NN
cord-341690-h8fqijk5	367	27	C	c	NN
cord-341690-h8fqijk5	367	28	for	for	IN
cord-341690-h8fqijk5	367	29	another	another	DT
cord-341690-h8fqijk5	367	30	3	3	CD
cord-341690-h8fqijk5	367	31	h.	h.	NN
cord-341690-h8fqijk5	368	1	The	the	DT
cord-341690-h8fqijk5	368	2	agarose	agarose	JJ
cord-341690-h8fqijk5	368	3	beads	bead	NNS
cord-341690-h8fqijk5	368	4	were	be	VBD
cord-341690-h8fqijk5	368	5	washed	wash	VBN
cord-341690-h8fqijk5	368	6	five	five	CD
cord-341690-h8fqijk5	368	7	times	time	NNS
cord-341690-h8fqijk5	368	8	with	with	IN
cord-341690-h8fqijk5	368	9	PBS	PBS	NNP
cord-341690-h8fqijk5	368	10	,	,	,
cord-341690-h8fqijk5	368	11	and	and	CC
cord-341690-h8fqijk5	368	12	the	the	DT
cord-341690-h8fqijk5	368	13	immunoprecipitated	immunoprecipitated	JJ
cord-341690-h8fqijk5	368	14	proteins	protein	NNS
cord-341690-h8fqijk5	368	15	were	be	VBD
cord-341690-h8fqijk5	368	16	analyzed	analyze	VBN
cord-341690-h8fqijk5	368	17	by	by	IN
cord-341690-h8fqijk5	368	18	Western	western	JJ
cord-341690-h8fqijk5	368	19	blotting	blot	VBG
cord-341690-h8fqijk5	368	20	with	with	IN
cord-341690-h8fqijk5	368	21	specific	specific	JJ
cord-341690-h8fqijk5	368	22	primary	primary	JJ
cord-341690-h8fqijk5	368	23	and	and	CC
cord-341690-h8fqijk5	368	24	secondary	secondary	JJ
cord-341690-h8fqijk5	368	25	antibodies	antibody	NNS
cord-341690-h8fqijk5	368	26	.	.	.
cord-341690-h8fqijk5	369	1	All	all	DT
cord-341690-h8fqijk5	369	2	results	result	NNS
cord-341690-h8fqijk5	369	3	are	be	VBP
cord-341690-h8fqijk5	369	4	presented	present	VBN
cord-341690-h8fqijk5	369	5	as	as	IN
cord-341690-h8fqijk5	369	6	means	mean	VBZ
cord-341690-h8fqijk5	369	7	±	±	NNP
cord-341690-h8fqijk5	369	8	standard	standard	JJ
cord-341690-h8fqijk5	369	9	deviation	deviation	NN
cord-341690-h8fqijk5	369	10	from	from	IN
cord-341690-h8fqijk5	369	11	three	three	CD
cord-341690-h8fqijk5	369	12	independent	independent	JJ
cord-341690-h8fqijk5	369	13	experiments	experiment	NNS
cord-341690-h8fqijk5	369	14	.	.	.
cord-341690-h8fqijk5	370	1	Significant	significant	JJ
cord-341690-h8fqijk5	370	2	differences	difference	NNS
cord-341690-h8fqijk5	370	3	between	between	IN
cord-341690-h8fqijk5	370	4	control	control	NN
cord-341690-h8fqijk5	370	5	and	and	CC
cord-341690-h8fqijk5	370	6	experimental	experimental	JJ
cord-341690-h8fqijk5	370	7	groups	group	NNS
cord-341690-h8fqijk5	370	8	were	be	VBD
cord-341690-h8fqijk5	370	9	analyzed	analyze	VBN
cord-341690-h8fqijk5	370	10	using	use	VBG
cord-341690-h8fqijk5	370	11	Student	Student	NNP
cord-341690-h8fqijk5	370	12	's	's	POS
cord-341690-h8fqijk5	370	13	t	t	NN
cord-341690-h8fqijk5	370	14	test	test	NN
cord-341690-h8fqijk5	370	15	.	.	.
cord-341690-h8fqijk5	371	1	Differences	difference	NNS
cord-341690-h8fqijk5	371	2	were	be	VBD
cord-341690-h8fqijk5	371	3	considered	consider	VBN
cord-341690-h8fqijk5	371	4	significant	significant	JJ
cord-341690-h8fqijk5	371	5	at	at	IN
cord-341690-h8fqijk5	371	6	*	*	NFP
cord-341690-h8fqijk5	371	7	0.01	0.01	CD
cord-341690-h8fqijk5	371	8	<	<	XX
cord-341690-h8fqijk5	371	9	p	p	XX
cord-341690-h8fqijk5	371	10	<	<	XX
cord-341690-h8fqijk5	371	11	0.05	0.05	CD
cord-341690-h8fqijk5	371	12	,	,	,
cord-341690-h8fqijk5	372	1	*	*	NFP
cord-341690-h8fqijk5	372	2	*	*	NFP
cord-341690-h8fqijk5	372	3	p	p	XX
cord-341690-h8fqijk5	372	4	<	<	XX
cord-341690-h8fqijk5	372	5	0.01	0.01	CD
cord-341690-h8fqijk5	372	6	.	.	.
cord-341690-h8fqijk5	373	1	Mechanisms	mechanism	NNS
cord-341690-h8fqijk5	373	2	of	of	IN
cord-341690-h8fqijk5	373	3	coronavirus	coronavirus	NN
cord-341690-h8fqijk5	373	4	cell	cell	NN
cord-341690-h8fqijk5	373	5	entry	entry	NN
cord-341690-h8fqijk5	373	6	mediated	mediate	VBN
cord-341690-h8fqijk5	373	7	by	by	IN
cord-341690-h8fqijk5	373	8	the	the	DT
cord-341690-h8fqijk5	373	9	viral	viral	JJ
cord-341690-h8fqijk5	373	10	spike	spike	NN
cord-341690-h8fqijk5	373	11	protein	protein	NN
cord-341690-h8fqijk5	373	12	Entry	entry	NN
cord-341690-h8fqijk5	373	13	and	and	CC
cord-341690-h8fqijk5	373	14	release	release	NN
cord-341690-h8fqijk5	373	15	of	of	IN
cord-341690-h8fqijk5	373	16	transmissible	transmissible	JJ
cord-341690-h8fqijk5	373	17	gastroenteritis	gastroenteritis	NN
cord-341690-h8fqijk5	373	18	coronavirus	coronavirus	NN
cord-341690-h8fqijk5	373	19	are	be	VBP
cord-341690-h8fqijk5	373	20	restricted	restrict	VBN
cord-341690-h8fqijk5	373	21	to	to	IN
cord-341690-h8fqijk5	373	22	apical	apical	JJ
cord-341690-h8fqijk5	373	23	surfaces	surface	NNS
cord-341690-h8fqijk5	373	24	of	of	IN
cord-341690-h8fqijk5	373	25	polarized	polarized	JJ
cord-341690-h8fqijk5	373	26	epithelial	epithelial	JJ
cord-341690-h8fqijk5	373	27	cells	cell	NNS
cord-341690-h8fqijk5	373	28	Porcine	porcine	JJ
cord-341690-h8fqijk5	373	29	IPEC	IPEC	NNP
cord-341690-h8fqijk5	373	30	-	-	HYPH
cord-341690-h8fqijk5	373	31	J2	j2	NN
cord-341690-h8fqijk5	373	32	intestinal	intestinal	JJ
cord-341690-h8fqijk5	373	33	epithelial	epithelial	JJ
cord-341690-h8fqijk5	373	34	cells	cell	NNS
cord-341690-h8fqijk5	373	35	in	in	IN
cord-341690-h8fqijk5	373	36	microbiological	microbiological	JJ
cord-341690-h8fqijk5	373	37	investigations	investigation	NNS
cord-341690-h8fqijk5	373	38	Subversion	Subversion	NNP
cord-341690-h8fqijk5	373	39	of	of	IN
cord-341690-h8fqijk5	373	40	the	the	DT
cord-341690-h8fqijk5	373	41	actin	actin	NN
cord-341690-h8fqijk5	373	42	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	373	43	during	during	IN
cord-341690-h8fqijk5	373	44	viral	viral	JJ
cord-341690-h8fqijk5	373	45	infection	infection	NN
cord-341690-h8fqijk5	374	1	The	the	DT
cord-341690-h8fqijk5	374	2	actin	actin	NN
cord-341690-h8fqijk5	374	3	cytoskeleton	cytoskeleton	NN
cord-341690-h8fqijk5	374	4	as	as	IN
cord-341690-h8fqijk5	374	5	a	a	DT
cord-341690-h8fqijk5	374	6	barrier	barrier	NN
cord-341690-h8fqijk5	374	7	to	to	IN
cord-341690-h8fqijk5	374	8	virus	virus	NN
cord-341690-h8fqijk5	374	9	infection	infection	NN
cord-341690-h8fqijk5	374	10	of	of	IN
cord-341690-h8fqijk5	374	11	polarized	polarized	JJ
cord-341690-h8fqijk5	374	12	epithelial	epithelial	JJ
cord-341690-h8fqijk5	374	13	cells	cell	NNS
cord-341690-h8fqijk5	374	14	Functions	function	NNS
cord-341690-h8fqijk5	374	15	of	of	IN
cord-341690-h8fqijk5	374	16	cofilin	cofilin	NN
cord-341690-h8fqijk5	374	17	in	in	IN
cord-341690-h8fqijk5	374	18	cell	cell	NN
cord-341690-h8fqijk5	374	19	locomotion	locomotion	NN
cord-341690-h8fqijk5	374	20	and	and	CC
cord-341690-h8fqijk5	374	21	invasion	invasion	NN
cord-341690-h8fqijk5	374	22	Signaling	signaling	NN
cord-341690-h8fqijk5	374	23	mechanisms	mechanism	NNS
cord-341690-h8fqijk5	374	24	and	and	CC
cord-341690-h8fqijk5	374	25	functional	functional	JJ
cord-341690-h8fqijk5	374	26	roles	role	NNS
cord-341690-h8fqijk5	374	27	of	of	IN
cord-341690-h8fqijk5	374	28	cofilin	cofilin	JJ
cord-341690-h8fqijk5	374	29	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	374	30	and	and	CC
cord-341690-h8fqijk5	374	31	dephosphorylation	dephosphorylation	NN
cord-341690-h8fqijk5	374	32	Rho	rho	NN
cord-341690-h8fqijk5	374	33	GTPases	gtpase	NNS
cord-341690-h8fqijk5	374	34	and	and	CC
cord-341690-h8fqijk5	374	35	actin	actin	NN
cord-341690-h8fqijk5	374	36	dynamics	dynamic	NNS
cord-341690-h8fqijk5	374	37	in	in	IN
cord-341690-h8fqijk5	374	38	membrane	membrane	NN
cord-341690-h8fqijk5	374	39	protrusions	protrusion	NNS
cord-341690-h8fqijk5	374	40	and	and	CC
cord-341690-h8fqijk5	375	1	vesicle	vesicle	NN
cord-341690-h8fqijk5	375	2	trafficking	traffic	VBG
cord-341690-h8fqijk5	375	3	Signalling	signal	VBG
cord-341690-h8fqijk5	375	4	through	through	IN
cord-341690-h8fqijk5	375	5	Class	class	NN
cord-341690-h8fqijk5	376	1	I	-PRON-	PRP
cord-341690-h8fqijk5	376	2	PI3Ks	PI3Ks	NNPS
cord-341690-h8fqijk5	376	3	in	in	IN
cord-341690-h8fqijk5	376	4	mammalian	mammalian	JJ
cord-341690-h8fqijk5	376	5	cells	cell	NNS
cord-341690-h8fqijk5	377	1	AKT	AKT	NNP
cord-341690-h8fqijk5	377	2	/	/	SYM
cord-341690-h8fqijk5	377	3	PKB	PKB	NNP
cord-341690-h8fqijk5	377	4	signaling	signal	VBG
cord-341690-h8fqijk5	377	5	:	:	:
cord-341690-h8fqijk5	377	6	navigating	navigate	VBG
cord-341690-h8fqijk5	377	7	downstream	downstream	RB
cord-341690-h8fqijk5	377	8	The	the	DT
cord-341690-h8fqijk5	377	9	epidermal	epidermal	JJ
cord-341690-h8fqijk5	377	10	growth	growth	NN
cord-341690-h8fqijk5	377	11	factor	factor	NN
cord-341690-h8fqijk5	377	12	receptor	receptor	NN
cord-341690-h8fqijk5	377	13	family	family	NN
cord-341690-h8fqijk5	377	14	as	as	IN
cord-341690-h8fqijk5	377	15	a	a	DT
cord-341690-h8fqijk5	377	16	central	central	JJ
cord-341690-h8fqijk5	377	17	element	element	NN
cord-341690-h8fqijk5	377	18	for	for	IN
cord-341690-h8fqijk5	377	19	cellular	cellular	JJ
cord-341690-h8fqijk5	377	20	signal	signal	NN
cord-341690-h8fqijk5	377	21	transduction	transduction	NN
cord-341690-h8fqijk5	377	22	and	and	CC
cord-341690-h8fqijk5	377	23	diversification	diversification	NN
cord-341690-h8fqijk5	377	24	Untangling	untangle	VBG
cord-341690-h8fqijk5	377	25	the	the	DT
cord-341690-h8fqijk5	377	26	ErbB	ErbB	NNP
cord-341690-h8fqijk5	377	27	signalling	signal	VBG
cord-341690-h8fqijk5	377	28	network	network	NN
cord-341690-h8fqijk5	377	29	Epidermal	epidermal	JJ
cord-341690-h8fqijk5	377	30	growth	growth	NN
cord-341690-h8fqijk5	377	31	factor	factor	NN
cord-341690-h8fqijk5	377	32	receptor	receptor	NN
cord-341690-h8fqijk5	377	33	:	:	:
cord-341690-h8fqijk5	377	34	mechanisms	mechanism	NNS
cord-341690-h8fqijk5	377	35	of	of	IN
cord-341690-h8fqijk5	377	36	activation	activation	NN
cord-341690-h8fqijk5	377	37	and	and	CC
cord-341690-h8fqijk5	377	38	signalling	signal	VBG
cord-341690-h8fqijk5	377	39	Internalization	internalization	NN
cord-341690-h8fqijk5	377	40	of	of	IN
cord-341690-h8fqijk5	377	41	the	the	DT
cord-341690-h8fqijk5	377	42	epidermal	epidermal	JJ
cord-341690-h8fqijk5	377	43	growth	growth	NN
cord-341690-h8fqijk5	377	44	factor	factor	NN
cord-341690-h8fqijk5	377	45	receptor	receptor	NN
cord-341690-h8fqijk5	377	46	:	:	:
cord-341690-h8fqijk5	377	47	role	role	NN
cord-341690-h8fqijk5	377	48	in	in	IN
cord-341690-h8fqijk5	377	49	signalling	signal	VBG
cord-341690-h8fqijk5	377	50	EGFR	EGFR	NNP
cord-341690-h8fqijk5	377	51	and	and	CC
cord-341690-h8fqijk5	377	52	EphA2	EphA2	NNP
cord-341690-h8fqijk5	377	53	are	be	VBP
cord-341690-h8fqijk5	377	54	host	host	NN
cord-341690-h8fqijk5	377	55	factors	factor	NNS
cord-341690-h8fqijk5	377	56	for	for	IN
cord-341690-h8fqijk5	377	57	hepatitis	hepatitis	NN
cord-341690-h8fqijk5	377	58	C	C	NNP
cord-341690-h8fqijk5	377	59	virus	virus	NN
cord-341690-h8fqijk5	377	60	entry	entry	NN
cord-341690-h8fqijk5	377	61	and	and	CC
cord-341690-h8fqijk5	377	62	possible	possible	JJ
cord-341690-h8fqijk5	377	63	targets	target	NNS
cord-341690-h8fqijk5	377	64	for	for	IN
cord-341690-h8fqijk5	377	65	antiviral	antiviral	JJ
cord-341690-h8fqijk5	377	66	therapy	therapy	NN
cord-341690-h8fqijk5	377	67	Activation	Activation	NNP
cord-341690-h8fqijk5	377	68	of	of	IN
cord-341690-h8fqijk5	377	69	EGFR	EGFR	NNP
cord-341690-h8fqijk5	377	70	on	on	IN
cord-341690-h8fqijk5	377	71	monocytes	monocyte	NNS
cord-341690-h8fqijk5	377	72	is	be	VBZ
cord-341690-h8fqijk5	377	73	required	require	VBN
cord-341690-h8fqijk5	377	74	for	for	IN
cord-341690-h8fqijk5	377	75	human	human	JJ
cord-341690-h8fqijk5	377	76	cytomegalovirus	cytomegalovirus	NN
cord-341690-h8fqijk5	377	77	entry	entry	NN
cord-341690-h8fqijk5	377	78	and	and	CC
cord-341690-h8fqijk5	377	79	mediates	mediate	VBZ
cord-341690-h8fqijk5	377	80	cellular	cellular	JJ
cord-341690-h8fqijk5	377	81	motility	motility	NN
cord-341690-h8fqijk5	378	1	The	the	DT
cord-341690-h8fqijk5	378	2	epidermal	epidermal	JJ
cord-341690-h8fqijk5	378	3	growth	growth	NN
cord-341690-h8fqijk5	378	4	factor	factor	NN
cord-341690-h8fqijk5	378	5	receptor	receptor	NN
cord-341690-h8fqijk5	378	6	(	(	-LRB-
cord-341690-h8fqijk5	378	7	EGFR	EGFR	NNP
cord-341690-h8fqijk5	378	8	)	)	-RRB-
cord-341690-h8fqijk5	378	9	promotes	promote	VBZ
cord-341690-h8fqijk5	378	10	uptake	uptake	NN
cord-341690-h8fqijk5	378	11	of	of	IN
cord-341690-h8fqijk5	378	12	influenza	influenza	NN
cord-341690-h8fqijk5	378	13	A	a	DT
cord-341690-h8fqijk5	378	14	viruses	virus	NNS
cord-341690-h8fqijk5	378	15	(	(	-LRB-
cord-341690-h8fqijk5	378	16	IAV	IAV	NNP
cord-341690-h8fqijk5	378	17	)	)	-RRB-
cord-341690-h8fqijk5	378	18	into	into	IN
cord-341690-h8fqijk5	378	19	host	host	NN
cord-341690-h8fqijk5	378	20	cells	cell	NNS
cord-341690-h8fqijk5	379	1	Epidermal	epidermal	JJ
cord-341690-h8fqijk5	379	2	Growth	growth	NN
cord-341690-h8fqijk5	379	3	Factor	Factor	NNP
cord-341690-h8fqijk5	379	4	Receptor	Receptor	NNP
cord-341690-h8fqijk5	379	5	-	-	HYPH
cord-341690-h8fqijk5	379	6	PI3	pi3	NN
cord-341690-h8fqijk5	379	7	K	K	NNP
cord-341690-h8fqijk5	379	8	Signaling	Signaling	NNP
cord-341690-h8fqijk5	379	9	Controls	control	VBZ
cord-341690-h8fqijk5	379	10	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	379	11	Activity	activity	NN
cord-341690-h8fqijk5	380	1	To	to	TO
cord-341690-h8fqijk5	380	2	Facilitate	facilitate	VB
cord-341690-h8fqijk5	380	3	Herpes	Herpes	NNP
cord-341690-h8fqijk5	380	4	Simplex	Simplex	NNP
cord-341690-h8fqijk5	380	5	Virus	virus	NN
cord-341690-h8fqijk5	380	6	1	1	CD
cord-341690-h8fqijk5	380	7	Entry	Entry	NNP
cord-341690-h8fqijk5	380	8	into	into	IN
cord-341690-h8fqijk5	380	9	Neuronal	Neuronal	NNP
cord-341690-h8fqijk5	380	10	Cells	Cells	NNPS
cord-341690-h8fqijk5	380	11	Actin	Actin	NNP
cord-341690-h8fqijk5	380	12	regulation	regulation	NN
cord-341690-h8fqijk5	380	13	in	in	IN
cord-341690-h8fqijk5	380	14	endocytosis	endocytosis	NN
cord-341690-h8fqijk5	380	15	Reactivation	reactivation	NN
cord-341690-h8fqijk5	380	16	of	of	IN
cord-341690-h8fqijk5	380	17	phosphorylated	phosphorylated	JJ
cord-341690-h8fqijk5	380	18	actin	actin	NN
cord-341690-h8fqijk5	380	19	depolymerizing	depolymerizing	NN
cord-341690-h8fqijk5	380	20	factor	factor	NN
cord-341690-h8fqijk5	380	21	and	and	CC
cord-341690-h8fqijk5	380	22	identification	identification	NN
cord-341690-h8fqijk5	380	23	of	of	IN
cord-341690-h8fqijk5	380	24	the	the	DT
cord-341690-h8fqijk5	380	25	regulatory	regulatory	JJ
cord-341690-h8fqijk5	380	26	site	site	NN
cord-341690-h8fqijk5	380	27	ADF	ADF	NNP
cord-341690-h8fqijk5	380	28	/	/	SYM
cord-341690-h8fqijk5	380	29	cofilin	cofilin	NN
cord-341690-h8fqijk5	380	30	:	:	:
cord-341690-h8fqijk5	380	31	a	a	DT
cord-341690-h8fqijk5	380	32	functional	functional	JJ
cord-341690-h8fqijk5	380	33	node	node	NN
cord-341690-h8fqijk5	380	34	in	in	IN
cord-341690-h8fqijk5	380	35	cell	cell	NN
cord-341690-h8fqijk5	380	36	biology	biology	NN
cord-341690-h8fqijk5	380	37	Transmissible	transmissible	JJ
cord-341690-h8fqijk5	380	38	gastroenteritis	gastroenteritis	NN
cord-341690-h8fqijk5	380	39	virus	virus	NN
cord-341690-h8fqijk5	380	40	and	and	CC
cord-341690-h8fqijk5	380	41	porcine	porcine	JJ
cord-341690-h8fqijk5	380	42	epidemic	epidemic	NN
cord-341690-h8fqijk5	380	43	diarrhoea	diarrhoea	NN
cord-341690-h8fqijk5	380	44	virus	virus	NN
cord-341690-h8fqijk5	380	45	infection	infection	NN
cord-341690-h8fqijk5	380	46	induces	induce	VBZ
cord-341690-h8fqijk5	380	47	dramatic	dramatic	JJ
cord-341690-h8fqijk5	380	48	changes	change	NNS
cord-341690-h8fqijk5	380	49	in	in	IN
cord-341690-h8fqijk5	380	50	the	the	DT
cord-341690-h8fqijk5	380	51	tight	tight	JJ
cord-341690-h8fqijk5	380	52	junctions	junction	NNS
cord-341690-h8fqijk5	380	53	and	and	CC
cord-341690-h8fqijk5	380	54	microfilaments	microfilament	NNS
cord-341690-h8fqijk5	380	55	of	of	IN
cord-341690-h8fqijk5	380	56	polarized	polarized	JJ
cord-341690-h8fqijk5	380	57	IPEC	IPEC	NNP
cord-341690-h8fqijk5	380	58	-	-	HYPH
cord-341690-h8fqijk5	380	59	J2	J2	NNP
cord-341690-h8fqijk5	380	60	cells	cell	VBZ
cord-341690-h8fqijk5	380	61	Localization	localization	NN
cord-341690-h8fqijk5	380	62	of	of	IN
cord-341690-h8fqijk5	380	63	epidermal	epidermal	JJ
cord-341690-h8fqijk5	380	64	growth	growth	NN
cord-341690-h8fqijk5	380	65	factor	factor	NN
cord-341690-h8fqijk5	380	66	-	-	HYPH
cord-341690-h8fqijk5	380	67	stimulated	stimulate	VBN
cord-341690-h8fqijk5	380	68	Ras/	Ras/	NNP
cord-341690-h8fqijk5	381	1	Raf-1	Raf-1	NNP
cord-341690-h8fqijk5	381	2	interaction	interaction	NN
cord-341690-h8fqijk5	381	3	to	to	IN
cord-341690-h8fqijk5	381	4	caveolae	caveolae	NNP
cord-341690-h8fqijk5	381	5	membrane	membrane	NN
cord-341690-h8fqijk5	381	6	Relationships	relationship	NNS
cord-341690-h8fqijk5	381	7	between	between	IN
cord-341690-h8fqijk5	381	8	EGFR	EGFR	NNP
cord-341690-h8fqijk5	381	9	signaling	signaling	NN
cord-341690-h8fqijk5	381	10	-	-	HYPH
cord-341690-h8fqijk5	381	11	competent	competent	JJ
cord-341690-h8fqijk5	381	12	and	and	CC
cord-341690-h8fqijk5	381	13	endocytosiscompetent	endocytosiscompetent	NN
cord-341690-h8fqijk5	381	14	membrane	membrane	NN
cord-341690-h8fqijk5	381	15	microdomains	microdomain	NNS
cord-341690-h8fqijk5	381	16	Lipid	Lipid	NNP
cord-341690-h8fqijk5	381	17	rafts	raft	NNS
cord-341690-h8fqijk5	381	18	as	as	IN
cord-341690-h8fqijk5	381	19	a	a	DT
cord-341690-h8fqijk5	381	20	membraneorganizing	membraneorganize	VBG
cord-341690-h8fqijk5	381	21	principle	principle	NN
cord-341690-h8fqijk5	382	1	A	a	DT
cord-341690-h8fqijk5	382	2	novel	novel	JJ
cord-341690-h8fqijk5	382	3	role	role	NN
cord-341690-h8fqijk5	382	4	for	for	IN
cord-341690-h8fqijk5	382	5	phagocytosis	phagocytosis	NN
cord-341690-h8fqijk5	382	6	-	-	HYPH
cord-341690-h8fqijk5	382	7	like	like	JJ
cord-341690-h8fqijk5	382	8	uptake	uptake	NN
cord-341690-h8fqijk5	382	9	in	in	IN
cord-341690-h8fqijk5	382	10	herpes	herpes	NNP
cord-341690-h8fqijk5	382	11	simplex	simplex	NNP
cord-341690-h8fqijk5	382	12	virus	virus	NN
cord-341690-h8fqijk5	382	13	entry	entry	NN
cord-341690-h8fqijk5	382	14	Actindependent	Actindependent	NNP
cord-341690-h8fqijk5	382	15	receptor	receptor	NN
cord-341690-h8fqijk5	382	16	colocalization	colocalization	NN
cord-341690-h8fqijk5	382	17	required	require	VBN
cord-341690-h8fqijk5	382	18	for	for	IN
cord-341690-h8fqijk5	382	19	human	human	JJ
cord-341690-h8fqijk5	382	20	immunodeficiency	immunodeficiency	NN
cord-341690-h8fqijk5	382	21	virus	virus	NN
cord-341690-h8fqijk5	382	22	entry	entry	NN
cord-341690-h8fqijk5	382	23	into	into	IN
cord-341690-h8fqijk5	382	24	host	host	NN
cord-341690-h8fqijk5	382	25	cells	cell	NNS
cord-341690-h8fqijk5	383	1	Vesicular	vesicular	JJ
cord-341690-h8fqijk5	383	2	stomatitis	stomatitis	NN
cord-341690-h8fqijk5	383	3	virus	virus	NN
cord-341690-h8fqijk5	383	4	enters	enter	VBZ
cord-341690-h8fqijk5	383	5	cells	cell	NNS
cord-341690-h8fqijk5	383	6	through	through	IN
cord-341690-h8fqijk5	383	7	vesicles	vesicle	NNS
cord-341690-h8fqijk5	383	8	incompletely	incompletely	RB
cord-341690-h8fqijk5	383	9	coated	coat	VBN
cord-341690-h8fqijk5	383	10	with	with	IN
cord-341690-h8fqijk5	383	11	clathrin	clathrin	NN
cord-341690-h8fqijk5	383	12	that	that	WDT
cord-341690-h8fqijk5	383	13	depend	depend	VBP
cord-341690-h8fqijk5	383	14	upon	upon	IN
cord-341690-h8fqijk5	383	15	actin	actin	NN
cord-341690-h8fqijk5	383	16	for	for	IN
cord-341690-h8fqijk5	383	17	internalization	internalization	NN
cord-341690-h8fqijk5	383	18	Expression	expression	NN
cord-341690-h8fqijk5	383	19	of	of	IN
cord-341690-h8fqijk5	383	20	rotavirus	rotavirus	JJ
cord-341690-h8fqijk5	383	21	NSP4	NSP4	NNP
cord-341690-h8fqijk5	383	22	alters	alter	VBZ
cord-341690-h8fqijk5	383	23	the	the	DT
cord-341690-h8fqijk5	383	24	actin	actin	NN
cord-341690-h8fqijk5	383	25	network	network	NN
cord-341690-h8fqijk5	383	26	organization	organization	NN
cord-341690-h8fqijk5	383	27	through	through	IN
cord-341690-h8fqijk5	383	28	the	the	DT
cord-341690-h8fqijk5	383	29	actin	actin	NN
cord-341690-h8fqijk5	383	30	remodeling	remodeling	NN
cord-341690-h8fqijk5	383	31	protein	protein	NN
cord-341690-h8fqijk5	384	1	cofilin	cofilin	NNP
cord-341690-h8fqijk5	384	2	HIV-1	HIV-1	NNP
cord-341690-h8fqijk5	384	3	Nef	Nef	NNP
cord-341690-h8fqijk5	384	4	interferes	interfere	VBZ
cord-341690-h8fqijk5	384	5	with	with	IN
cord-341690-h8fqijk5	384	6	host	host	NN
cord-341690-h8fqijk5	384	7	cell	cell	NN
cord-341690-h8fqijk5	384	8	motility	motility	NN
cord-341690-h8fqijk5	384	9	by	by	IN
cord-341690-h8fqijk5	384	10	deregulation	deregulation	NN
cord-341690-h8fqijk5	384	11	of	of	IN
cord-341690-h8fqijk5	384	12	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	384	13	Initiation	Initiation	NNP
cord-341690-h8fqijk5	384	14	of	of	IN
cord-341690-h8fqijk5	384	15	cofilin	cofilin	JJ
cord-341690-h8fqijk5	384	16	activity	activity	NN
cord-341690-h8fqijk5	384	17	in	in	IN
cord-341690-h8fqijk5	384	18	response	response	NN
cord-341690-h8fqijk5	384	19	to	to	IN
cord-341690-h8fqijk5	384	20	EGF	EGF	NNP
cord-341690-h8fqijk5	384	21	is	be	VBZ
cord-341690-h8fqijk5	384	22	uncoupled	uncouple	VBN
cord-341690-h8fqijk5	384	23	from	from	IN
cord-341690-h8fqijk5	384	24	cofilin	cofilin	JJ
cord-341690-h8fqijk5	384	25	phosphorylation	phosphorylation	NN
cord-341690-h8fqijk5	384	26	and	and	CC
cord-341690-h8fqijk5	384	27	dephosphorylation	dephosphorylation	NN
cord-341690-h8fqijk5	384	28	in	in	IN
cord-341690-h8fqijk5	384	29	carcinoma	carcinoma	NN
cord-341690-h8fqijk5	384	30	cells	cell	NNS
cord-341690-h8fqijk5	385	1	Cytoplasmic	cytoplasmic	JJ
cord-341690-h8fqijk5	385	2	localization	localization	NN
cord-341690-h8fqijk5	385	3	and	and	CC
cord-341690-h8fqijk5	385	4	nuclear	nuclear	JJ
cord-341690-h8fqijk5	385	5	transport	transport	NN
cord-341690-h8fqijk5	385	6	of	of	IN
cord-341690-h8fqijk5	385	7	cofilin	cofilin	NN
cord-341690-h8fqijk5	385	8	in	in	IN
cord-341690-h8fqijk5	385	9	cultured	cultured	JJ
cord-341690-h8fqijk5	385	10	myotubes	myotube	NNS
cord-341690-h8fqijk5	385	11	Cloning	cloning	NN
cord-341690-h8fqijk5	385	12	and	and	CC
cord-341690-h8fqijk5	385	13	characterization	characterization	NN
cord-341690-h8fqijk5	385	14	of	of	IN
cord-341690-h8fqijk5	385	15	porcine	porcine	JJ
cord-341690-h8fqijk5	385	16	brain	brain	NN
cord-341690-h8fqijk5	385	17	cofilin	cofilin	NN
cord-341690-h8fqijk5	385	18	cDNA	cdna	NN
cord-341690-h8fqijk5	385	19	.	.	.
cord-341690-h8fqijk5	386	1	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	386	2	contains	contain	VBZ
cord-341690-h8fqijk5	386	3	the	the	DT
cord-341690-h8fqijk5	386	4	nuclear	nuclear	JJ
cord-341690-h8fqijk5	386	5	transport	transport	NN
cord-341690-h8fqijk5	386	6	signal	signal	NN
cord-341690-h8fqijk5	386	7	sequence	sequence	NN
cord-341690-h8fqijk5	386	8	Dephosphorylation	dephosphorylation	NN
cord-341690-h8fqijk5	386	9	of	of	IN
cord-341690-h8fqijk5	386	10	serine	serine	NN
cord-341690-h8fqijk5	386	11	3	3	CD
cord-341690-h8fqijk5	386	12	regulates	regulate	VBZ
cord-341690-h8fqijk5	386	13	nuclear	nuclear	JJ
cord-341690-h8fqijk5	386	14	translocation	translocation	NN
cord-341690-h8fqijk5	386	15	of	of	IN
cord-341690-h8fqijk5	386	16	cofilin	cofilin	JJ
cord-341690-h8fqijk5	386	17	Cofilin	Cofilin	NNP
cord-341690-h8fqijk5	386	18	produces	produce	VBZ
cord-341690-h8fqijk5	386	19	newly	newly	RB
cord-341690-h8fqijk5	386	20	polymerized	polymerize	VBN
cord-341690-h8fqijk5	386	21	actin	actin	NN
cord-341690-h8fqijk5	386	22	filaments	filament	NNS
cord-341690-h8fqijk5	386	23	that	that	WDT
cord-341690-h8fqijk5	386	24	are	be	VBP
cord-341690-h8fqijk5	386	25	preferred	prefer	VBN
cord-341690-h8fqijk5	386	26	for	for	IN
cord-341690-h8fqijk5	386	27	dendritic	dendritic	JJ
cord-341690-h8fqijk5	386	28	nucleation	nucleation	NN
cord-341690-h8fqijk5	386	29	by	by	IN
cord-341690-h8fqijk5	386	30	the	the	DT
cord-341690-h8fqijk5	386	31	Arp2/3	Arp2/3	NNP
cord-341690-h8fqijk5	386	32	complex	complex	NN
cord-341690-h8fqijk5	386	33	.	.	.
cord-341690-h8fqijk5	387	1	Current	current	JJ
cord-341690-h8fqijk5	387	2	biology	biology	NN
cord-341690-h8fqijk5	388	1	The	the	DT
cord-341690-h8fqijk5	388	2	activity	activity	NN
cord-341690-h8fqijk5	388	3	status	status	NN
cord-341690-h8fqijk5	388	4	of	of	IN
cord-341690-h8fqijk5	388	5	cofilin	cofilin	NN
cord-341690-h8fqijk5	388	6	is	be	VBZ
cord-341690-h8fqijk5	388	7	directly	directly	RB
cord-341690-h8fqijk5	388	8	related	relate	VBN
cord-341690-h8fqijk5	388	9	to	to	IN
cord-341690-h8fqijk5	388	10	invasion	invasion	NN
cord-341690-h8fqijk5	388	11	,	,	,
cord-341690-h8fqijk5	388	12	www.impactjournals.com/oncotarget	www.impactjournals.com/oncotarget	NNP
cord-341690-h8fqijk5	388	13	intravasation	intravasation	NN
cord-341690-h8fqijk5	388	14	,	,	,
cord-341690-h8fqijk5	388	15	and	and	CC
cord-341690-h8fqijk5	388	16	metastasis	metastasis	NN
cord-341690-h8fqijk5	388	17	of	of	IN
cord-341690-h8fqijk5	388	18	mammary	mammary	JJ
cord-341690-h8fqijk5	388	19	tumors	tumor	NNS
cord-341690-h8fqijk5	388	20	EGF	EGF	NNP
cord-341690-h8fqijk5	388	21	-	-	HYPH
cord-341690-h8fqijk5	388	22	induced	induce	VBN
cord-341690-h8fqijk5	388	23	PIP2	PIP2	NNP
cord-341690-h8fqijk5	388	24	hydrolysis	hydrolysis	NN
cord-341690-h8fqijk5	388	25	releases	release	NNS
cord-341690-h8fqijk5	388	26	and	and	CC
cord-341690-h8fqijk5	388	27	activates	activate	VBZ
cord-341690-h8fqijk5	388	28	cofilin	cofilin	NN
cord-341690-h8fqijk5	388	29	locally	locally	RB
cord-341690-h8fqijk5	388	30	in	in	IN
cord-341690-h8fqijk5	388	31	carcinoma	carcinoma	NN
cord-341690-h8fqijk5	388	32	cells	cell	NNS
cord-341690-h8fqijk5	389	1	Mammalian	mammalian	JJ
cord-341690-h8fqijk5	389	2	Rho	rho	NN
cord-341690-h8fqijk5	389	3	GTPases	gtpase	NNS
cord-341690-h8fqijk5	389	4	:	:	:
cord-341690-h8fqijk5	390	1	new	new	JJ
cord-341690-h8fqijk5	390	2	insights	insight	NNS
cord-341690-h8fqijk5	390	3	into	into	IN
cord-341690-h8fqijk5	390	4	their	-PRON-	PRP$
cord-341690-h8fqijk5	390	5	functions	function	NNS
cord-341690-h8fqijk5	390	6	from	from	IN
cord-341690-h8fqijk5	390	7	in	in	IN
cord-341690-h8fqijk5	390	8	vivo	vivo	NNP
cord-341690-h8fqijk5	390	9	studies	study	NNS
cord-341690-h8fqijk5	391	1	HER2	HER2	NNP
cord-341690-h8fqijk5	391	2	/	/	SYM
cord-341690-h8fqijk5	391	3	Neu	Neu	NNP
cord-341690-h8fqijk5	391	4	(	(	-LRB-
cord-341690-h8fqijk5	391	5	ErbB2	ErbB2	NNP
cord-341690-h8fqijk5	391	6	)	)	-RRB-
cord-341690-h8fqijk5	391	7	signaling	signal	VBG
cord-341690-h8fqijk5	391	8	to	to	IN
cord-341690-h8fqijk5	391	9	Rac1-Pak1	rac1-pak1	PRP
cord-341690-h8fqijk5	391	10	is	be	VBZ
cord-341690-h8fqijk5	391	11	temporally	temporally	RB
cord-341690-h8fqijk5	391	12	and	and	CC
cord-341690-h8fqijk5	391	13	spatially	spatially	RB
cord-341690-h8fqijk5	391	14	modulated	modulate	VBN
cord-341690-h8fqijk5	391	15	by	by	IN
cord-341690-h8fqijk5	391	16	transforming	transform	VBG
cord-341690-h8fqijk5	391	17	growth	growth	NN
cord-341690-h8fqijk5	391	18	factor	factor	NN
cord-341690-h8fqijk5	392	1	β	β	NN
cord-341690-h8fqijk5	392	2	Rho	Rho	NNP
cord-341690-h8fqijk5	392	3	GTPases	gtpase	NNS
cord-341690-h8fqijk5	392	4	modulate	modulate	VBP
cord-341690-h8fqijk5	392	5	entry	entry	NN
cord-341690-h8fqijk5	392	6	of	of	IN
cord-341690-h8fqijk5	392	7	Ebola	Ebola	NNP
cord-341690-h8fqijk5	392	8	virus	virus	NN
cord-341690-h8fqijk5	392	9	and	and	CC
cord-341690-h8fqijk5	392	10	vesicular	vesicular	JJ
cord-341690-h8fqijk5	392	11	stomatitis	stomatitis	NN
cord-341690-h8fqijk5	392	12	virus	virus	NN
cord-341690-h8fqijk5	392	13	pseudotyped	pseudotyped	NNP
cord-341690-h8fqijk5	392	14	vectors	vector	NNS
cord-341690-h8fqijk5	392	15	Phosphoinositide-3	Phosphoinositide-3	NNP
cord-341690-h8fqijk5	393	1	kinase	kinase	LS
cord-341690-h8fqijk5	393	2	-	-	HYPH
cord-341690-h8fqijk5	393	3	Akt	Akt	NNP
cord-341690-h8fqijk5	393	4	pathway	pathway	NN
cord-341690-h8fqijk5	393	5	controls	control	VBZ
cord-341690-h8fqijk5	393	6	cellular	cellular	JJ
cord-341690-h8fqijk5	393	7	entry	entry	NN
cord-341690-h8fqijk5	393	8	of	of	IN
cord-341690-h8fqijk5	393	9	Ebola	Ebola	NNP
cord-341690-h8fqijk5	393	10	virus	virus	NN
cord-341690-h8fqijk5	393	11	Kaposi	Kaposi	NNP
cord-341690-h8fqijk5	393	12	's	's	POS
cord-341690-h8fqijk5	393	13	sarcoma	sarcoma	NN
cord-341690-h8fqijk5	393	14	-	-	HYPH
cord-341690-h8fqijk5	393	15	associated	associate	VBN
cord-341690-h8fqijk5	393	16	herpesvirus	herpesvirus	NN
cord-341690-h8fqijk5	393	17	induces	induce	VBZ
cord-341690-h8fqijk5	393	18	the	the	DT
cord-341690-h8fqijk5	393	19	phosphatidylinositol	phosphatidylinositol	JJ
cord-341690-h8fqijk5	393	20	3-kinase	3-kinase	NNP
cord-341690-h8fqijk5	393	21	-	-	HYPH
cord-341690-h8fqijk5	393	22	PKC	PKC	NNP
cord-341690-h8fqijk5	393	23	-	-	HYPH
cord-341690-h8fqijk5	393	24	ζ	ζ	NN
cord-341690-h8fqijk5	393	25	-	-	HYPH
cord-341690-h8fqijk5	393	26	MEK	mek	NN
cord-341690-h8fqijk5	393	27	-	-	HYPH
cord-341690-h8fqijk5	393	28	ERK	ERK	NNP
cord-341690-h8fqijk5	393	29	signaling	signal	VBG
cord-341690-h8fqijk5	393	30	pathway	pathway	NN
cord-341690-h8fqijk5	393	31	in	in	IN
cord-341690-h8fqijk5	393	32	target	target	NN
cord-341690-h8fqijk5	393	33	cells	cell	NNS
cord-341690-h8fqijk5	393	34	early	early	RB
cord-341690-h8fqijk5	393	35	during	during	IN
cord-341690-h8fqijk5	393	36	infection	infection	NN
cord-341690-h8fqijk5	393	37	:	:	:
cord-341690-h8fqijk5	394	1	implications	implication	NNS
cord-341690-h8fqijk5	394	2	for	for	IN
cord-341690-h8fqijk5	394	3	infectivity	infectivity	NN
cord-341690-h8fqijk5	394	4	Influenza	Influenza	NNP
cord-341690-h8fqijk5	394	5	virus	virus	NN
cord-341690-h8fqijk5	394	6	propagation	propagation	NN
cord-341690-h8fqijk5	394	7	is	be	VBZ
cord-341690-h8fqijk5	394	8	impaired	impair	VBN
cord-341690-h8fqijk5	394	9	by	by	IN
cord-341690-h8fqijk5	394	10	inhibition	inhibition	NN
cord-341690-h8fqijk5	394	11	of	of	IN
cord-341690-h8fqijk5	394	12	the	the	DT
cord-341690-h8fqijk5	394	13	Raf	Raf	NNP
cord-341690-h8fqijk5	394	14	/	/	SYM
cord-341690-h8fqijk5	394	15	MEK	MEK	NNP
cord-341690-h8fqijk5	394	16	/	/	SYM
cord-341690-h8fqijk5	394	17	ERK	ERK	NNP
cord-341690-h8fqijk5	395	1	signalling	signal	VBG
cord-341690-h8fqijk5	395	2	cascade	cascade	NN
cord-341690-h8fqijk5	395	3	Virus	Virus	NNP
cord-341690-h8fqijk5	395	4	activated	activate	VBD
cord-341690-h8fqijk5	395	5	filopodia	filopodia	NNS
cord-341690-h8fqijk5	395	6	promote	promote	VBP
cord-341690-h8fqijk5	395	7	human	human	JJ
cord-341690-h8fqijk5	395	8	papillomavirus	papillomavirus	NN
cord-341690-h8fqijk5	395	9	type	type	NN
cord-341690-h8fqijk5	395	10	31	31	CD
cord-341690-h8fqijk5	395	11	uptake	uptake	NN
cord-341690-h8fqijk5	395	12	from	from	IN
cord-341690-h8fqijk5	395	13	the	the	DT
cord-341690-h8fqijk5	395	14	extracellular	extracellular	JJ
cord-341690-h8fqijk5	395	15	matrix	matrix	NN
cord-341690-h8fqijk5	395	16	Evidence	evidence	NN
cord-341690-h8fqijk5	395	17	for	for	IN
cord-341690-h8fqijk5	395	18	a	a	DT
cord-341690-h8fqijk5	395	19	putative	putative	JJ
cord-341690-h8fqijk5	395	20	second	second	JJ
cord-341690-h8fqijk5	395	21	receptor	receptor	NN
cord-341690-h8fqijk5	395	22	for	for	IN
cord-341690-h8fqijk5	395	23	porcine	porcine	JJ
cord-341690-h8fqijk5	395	24	transmissible	transmissible	JJ
cord-341690-h8fqijk5	395	25	gastroenteritis	gastroenteritis	NN
cord-341690-h8fqijk5	395	26	virus	virus	NN
cord-341690-h8fqijk5	395	27	on	on	IN
cord-341690-h8fqijk5	395	28	the	the	DT
cord-341690-h8fqijk5	395	29	villous	villous	NNP
cord-341690-h8fqijk5	395	30	enterocytes	enterocytes	NNPS
cord-341690-h8fqijk5	395	31	of	of	IN
cord-341690-h8fqijk5	395	32	newborn	newborn	JJ
cord-341690-h8fqijk5	395	33	pigs	pig	NNS
cord-341690-h8fqijk5	395	34	Cold	Cold	NNP
cord-341690-h8fqijk5	395	35	Spring	Spring	NNP
cord-341690-h8fqijk5	395	36	Harbor	Harbor	NNP
cord-341690-h8fqijk5	395	37	perspectives	perspective	NNS
cord-341690-h8fqijk5	395	38	in	in	IN
cord-341690-h8fqijk5	395	39	biology	biology	NN
cord-341690-h8fqijk5	395	40	Critical	critical	JJ
cord-341690-h8fqijk5	395	41	role	role	NN
cord-341690-h8fqijk5	395	42	for	for	IN
cord-341690-h8fqijk5	395	43	lipid	lipid	NN
cord-341690-h8fqijk5	395	44	raft	raft	NN
cord-341690-h8fqijk5	395	45	-	-	HYPH
cord-341690-h8fqijk5	395	46	associated	associate	VBN
cord-341690-h8fqijk5	395	47	Src	Src	NNP
cord-341690-h8fqijk5	395	48	kinases	kinase	NNS
cord-341690-h8fqijk5	395	49	in	in	IN
cord-341690-h8fqijk5	395	50	activation	activation	NN
cord-341690-h8fqijk5	395	51	of	of	IN
cord-341690-h8fqijk5	395	52	PI3K	PI3K	NNP
cord-341690-h8fqijk5	395	53	-	-	HYPH
cord-341690-h8fqijk5	395	54	Akt	Akt	NNP
cord-341690-h8fqijk5	395	55	signalling	signal	VBG
cord-341690-h8fqijk5	395	56	Actin	Actin	NNP
cord-341690-h8fqijk5	395	57	in	in	IN
cord-341690-h8fqijk5	395	58	the	the	DT
cord-341690-h8fqijk5	395	59	endocytic	endocytic	JJ
cord-341690-h8fqijk5	395	60	pathway	pathway	NN
cord-341690-h8fqijk5	395	61	:	:	:
cord-341690-h8fqijk5	395	62	from	from	IN
cord-341690-h8fqijk5	395	63	yeast	yeast	NN
cord-341690-h8fqijk5	395	64	to	to	IN
cord-341690-h8fqijk5	395	65	mammals	mammal	NNS
cord-341690-h8fqijk5	395	66	Complete	complete	VB
cord-341690-h8fqijk5	395	67	genomic	genomic	JJ
cord-341690-h8fqijk5	395	68	sequence	sequence	NN
cord-341690-h8fqijk5	395	69	of	of	IN
cord-341690-h8fqijk5	395	70	the	the	DT
cord-341690-h8fqijk5	395	71	coronavirus	coronavirus	NN
cord-341690-h8fqijk5	395	72	transmissible	transmissible	JJ
cord-341690-h8fqijk5	395	73	gastroenteritis	gastroenteritis	NN
cord-341690-h8fqijk5	395	74	virus	virus	NN
cord-341690-h8fqijk5	395	75	SHXB	SHXB	NNP
cord-341690-h8fqijk5	395	76	isolated	isolate	VBN
cord-341690-h8fqijk5	395	77	in	in	IN
cord-341690-h8fqijk5	395	78	China	China	NNP
cord-341690-h8fqijk5	395	79	General	General	NNP
cord-341690-h8fqijk5	395	80	morphology	morphology	NN
cord-341690-h8fqijk5	395	81	and	and	CC
cord-341690-h8fqijk5	395	82	capsid	capsid	JJ
cord-341690-h8fqijk5	395	83	fine	fine	JJ
cord-341690-h8fqijk5	395	84	structure	structure	NN
cord-341690-h8fqijk5	395	85	of	of	IN
cord-341690-h8fqijk5	395	86	African	african	JJ
cord-341690-h8fqijk5	395	87	swine	swine	NN
cord-341690-h8fqijk5	395	88	fever	fever	NN
cord-341690-h8fqijk5	395	89	virus	virus	NN
cord-341690-h8fqijk5	395	90	particles	particle	NNS
cord-341690-h8fqijk5	396	1	There	there	EX
cord-341690-h8fqijk5	396	2	is	be	VBZ
cord-341690-h8fqijk5	396	3	no	no	DT
cord-341690-h8fqijk5	396	4	conflict	conflict	NN
cord-341690-h8fqijk5	396	5	of	of	IN
cord-341690-h8fqijk5	396	6	interest	interest	NN