id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-270586-ohs8z91m	Ballesteros, M. L.	Two Amino Acid Changes at the N-Terminus of Transmissible Gastroenteritis Coronavirus Spike Protein Result in the Loss of Enteric Tropism	1997-01-20		.txt	text/plain	6016	331	56	PRCVs replicate to high titers only in al ., 1990) , and TGEV entry into swine testis (ST) cells the respiratory tract (Cox et al., 1990) and have a large is mediated through interactions between the virus S deletion at the 5 end of the spike gene, in positions glycoprotein and the porcine aminopeptidase N (pAPN) ranging from nucleotides (nt) 45 to 745 (Enjuanes and which serves as the cellular receptor (Delmas et al., Van der Zeijst, 1995; Sá nchez et al., 1992; Vaughn et al., 1992) . Studies changes located in the S protein gene, at positions 214, 655, and 2098, were involved in the control of the enteric on the inhibition of virus binding to cells indicated that the receptor binding site for TGEV had to be located tropism, recombinant viruses containing one or the three nucleotide differences from the respiratory isolate were between antigenic sites D and A of the spike protein (Suñé et al., 1990) , mapping between amino acids 385 selected.	./cache/cord-270586-ohs8z91m.txt	./txt/cord-270586-ohs8z91m.txt