id author title date pages extension mime words sentences flesch summary cache txt cord-003976-05tf6oqa Wang, Kai Anti-TGEV Miller Strain Infection Effect of Lactobacillus plantarum Supernatant Based on the JAK-STAT1 Signaling Pathway 2019-11-06 .txt text/plain 6952 350 57 Lp-1s could induce large amounts of interferon-β in IPEC-J2 cells in the early stage (6 h) of infection with TGEV, and increased the level of phosphorylated signal transducer and activator of transcription and its nuclear translocation in the late stage (24–48 h) of infection. We found that the mRNA expression levels of ZAP, MX2, MX1, PKR, OASL, and ISG15 were significantly higher in the Lp-1s treated group than in the TGEV infected group at various points after infection. In the present study, we found that IPEC-J2 cells still produced IFN-β after infection with TGEV, which increased with time, (F) Relative expression of p-STAT1/STAT1 in Lp-1s treatment group was significantly higher than TGEV infected alone at 24 h ( * P < 0.05). The induced level of IFN-β in Lp-1s-treated IPEC-J2 cells was significantly different from that in the TGEV infected group at the same time point. ./cache/cord-003976-05tf6oqa.txt ./txt/cord-003976-05tf6oqa.txt