id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-326148-9wpxm5of	Van Walle, I.	Meta-analysis of the clinical performance of commercial SARS-CoV-2 nucleic acid, antigen and antibody tests up to 22 August 2020	2020-09-18		.txt	text/plain	3790	218	49	title: Meta-analysis of the clinical performance of commercial SARS-CoV-2 nucleic acid, antigen and antibody tests up to 22 August 2020 We reviewed the clinical performance of SARS-CoV-2 nucleic acid, viral antigen and antibody tests based on 94739 test results from 157 published studies and 20205 new test results from 12 EU/EEA Member States. Pooling the results and considering only results with 95% confidence interval width [≤]5%, we found 4 nucleic acid tests, among which 1 point of care test, and 3 antibody tests with a clinical sensitivity [≤]95% for at least one target population (hospitalised, mild or asymptomatic, or unknown). Study heterogeneity was low for 8/14 (57.1%) sensitivity and 68/84 (81.0%) specificity results with confidence interval width [≤]5%, and lower for nucleic acid tests than antibody tests. Studies containing potentially usable data on clinical performance of SARS-CoV-2 nucleic acid, antigen and antibody tests were first extracted from systematic reviews on this topic.	./cache/cord-326148-9wpxm5of.txt	./txt/cord-326148-9wpxm5of.txt