id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-281668-960trqex	Dana, Dibyendu	A Review of Small Molecule Inhibitors and Functional Probes of Human Cathepsin L	2020-02-06		.txt	text/plain	21990	1128	44	These inhibitors further provided the option of varying the leaving group that targets S2� site; more hydrophobic substituents were preferred at this position as comparison of ki/Ki values of the inactivation exhibited the following trend for Aa: Gly < Ala < Val < Leu < Phe < 4-NO2-Ph. The nitrophenyl analog (Entry 7, Table 2 ) which incur both hydrophobicity and electron-withdrawing property exerted the maximum potency and selectivity for cathepsin L over other tested cysteine proteases. These inhibitors further provided the option of varying the leaving group that targets S2� site; more hydrophobic substituents were preferred at this position as comparison of ki/Ki values of the inactivation exhibited the following trend for Aa: Gly < Ala < Val < Leu < Phe < 4-NO2-Ph. The nitrophenyl analog (Entry 7, Table 2 ) which incur both hydrophobicity and electron-withdrawing property exerted the maximum potency and selectivity for cathepsin L over other tested cysteine proteases.	./cache/cord-281668-960trqex.txt	./txt/cord-281668-960trqex.txt