id author title date pages extension mime words sentences flesch summary cache txt cord-273992-xddikzxs Wiseman, A. Avoidance of oxidative‐stress perturbation in yeast bioprocesses by proteomic and genomic biostrategies? 2004-11-10 .txt text/plain 2658 122 35 The main impact of the study is that the utilization of genetically modified (GM) yeast produced by recombinant DNA technology genomic strategies could circumvent the bioprocessing problems that otherwise result from the bioprocess perturbations: this is as a result of oxidative stress caused by ROS, which is avoidable by deployment of appropriate antioxidants such as vitamins E, C and D (and antioxidant proteins and enzymes often of microbial origin via recombinant DNA technology). Catalases ( Table 3 ) in yeasts and other micro-organisms (Antioxidants such as vitamins E and C chain terminate the formation of membrane-degrading ROS) relates to more than just structural damage that is sometimes obvious and predictable: functional damage may also follow. Avoidance biostrategies against ROS and RSS in many oxidatively stressed bioprocesses that utilise yeasts (and other micro-organisms) are essential where human therapeutic proteins are expected to be produced in high yield. ./cache/cord-273992-xddikzxs.txt ./txt/cord-273992-xddikzxs.txt