id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-102319-2b404su7	Kang, J.	Increased brain volume from cereal, decreased brain volume from coffee -- shared genetic determinants and impacts on cognitive function, body mass index (BMI) and other metabolic measures: cohort study of UK Biobank participants	2020-10-14		.txt	text/plain	6547	338	47	title: Increased brain volume from cereal, decreased brain volume from coffee -shared genetic determinants and impacts on cognitive function, body mass index (BMI) and other metabolic measures: cohort study of UK Biobank participants Results: We investigated diet effects in the UK Biobank data and discovered anti-correlated brain-wide grey matter volume (GMV)-association patterns between coffee and cereal intake, coincidence with their anti-correlated genetic constructs. These genetic factors may further affect people's lifestyle habits and body/blood fat levels through the mediation of cereal/coffee intake, and the brain-wide expression pattern of gene CPLX3, a dedicated marker of subplate neurons that regulate cortical development and plasticity, may underlie the shared GMV-association patterns among the coffee/cereal intake and cognitive functions. To further understand the biological insights of the shared variants of cereal intake and coffee intake, we performed linear regression analysis to examine the pairwise associations between the independent lead SNPs and other diets, lifestyle, and body/blood fat covarying age, sex, the top 40 25 genetic principal components.	./cache/cord-102319-2b404su7.txt	./txt/cord-102319-2b404su7.txt