id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-032491-tycd2i95	Severino, Amie L.	μ-Opioid Receptors on Distinct Neuronal Populations Mediate Different Aspects of Opioid Reward-Related Behaviors	2020-09-18		.txt	text/plain	7881	387	54	Between genotype analysis (Table 4 , item e) showed a similar effect of genotype following morphine as oxycodone treatment in that, when compared with flMORs, A2aflMORs showed an enhanced response at the higher doses used, 10 (p = 0.0001) and 15 (p = 0.004) mg/kg, whereas D1flMORs showed a reduced response at 15 mg/kg (p = 0.004), but not 10 mg/kg. The flMORs showed a genotype  day interaction as both oxycodone (p = 0.002) and morphine (p = 0.02), but not saline, induced sensitization ( Fig. 3D ; Table 4 , item h). The D1flMORs showed no sensitization effect following oxycodone or morphine and this response was not different from saline ( Fig. 3E ; Table 4 , item i). Our findings show that this A2a-MOR population is an apparent subset of D2 medium spiny neurons that controls the locomotor sensitivity to oxycodone and morphine and drug-seeking behavior during extinction. Deleting MORs from ChAT neurons does not alter oxycodone-induced hyperlocomotion and sensitization but does increase the locomotor effect of cocaine and drug-seeking behaviors following opioid IVSA.	./cache/cord-032491-tycd2i95.txt	./txt/cord-032491-tycd2i95.txt