id author title date pages extension mime words sentences flesch summary cache txt cord-001890-kbiwze0z Zhang, Huimin Two novel regulators of N‐acetyl‐galactosamine utilization pathway and distinct roles in bacterial infections 2015-11-05 .txt text/plain 9571 514 51 coli, not only does AgaR regulator that belongs to the DeoR family of transcriptional factors, act as an autoregulator, but also negatively controls the expression of two aga genes (agaZ and agaS) of GalN/ GalNAc catabolism pathway via direct binding of the specific palindromes in front of these target genes (Ray and Larson 2004) . Discovery of the genome-wide regulons encoding the GalNAc/GalN utilization pathways in Lactobacillales Arrows represent the GalNAc/ GalN catabolism-related genes, and circles denote the predicted AgaR-recognizable sites. (B) Real-time qPCR assays for effects of agaR2 on expression profile of genes of GalNAc/GalN utilization pathway in Streptococcus suis. The approach includes inference of transcriptional factor-binding sites (TFBSs), construction of nucleotide positional weight matrices (PWMs) for TFBSs motifs, and reconstruction of regulons in complete genomes on the basis of prediction of putative TFBSs in the promoter gene regions. suis 05ZYH33 (Accession no.: CP000407.1) encodes a fully functional GalNAc utilization machinery and most of the genes encoding this pathway are regulated by AgaR2 (and/or AgaR1) (Fig. 1) . ./cache/cord-001890-kbiwze0z.txt ./txt/cord-001890-kbiwze0z.txt