id author title date pages extension mime words sentences flesch summary cache txt cord-265563-1k8v0luz Sperlich, Johannes M. Respiratory Infections and Antibiotic Usage in Common Variable Immunodeficiency 2017-07-19 .txt text/plain 6518 366 46 Abbreviations used COPD-Chronic obstructive pulmonary disease CVID-Common variable immunodeficiency HR-Hazard ratio IQR-Interquartile range OAT-Oral antibiotic therapy OR-Odds ratio SGRQ-St George's Respiratory Questionnaire TE-Treated exacerbation TSE-Treated symptomatic exacerbation USE-Untreated symptomatic exacerbation between 1 in 10,000 and 1 in 50,000, it is the most common symptomatic primary immunodeficiency. Exacerbations characterized by purulent sputum respond rapidly to antibiotics, whereas those characterized by upper respiratory tract symptoms and sore throat respond more slowly Median (IQR) time until recovery after start of OAT in all TEs was 6.5 (5-14) days ( Figure 4 , A). For USEs, the differences in Regarding the impact of antibiotic prophylaxis on exacerbation severity, there was no significant difference in episode duration or cumulative total symptom count during symptomatic exacerbations between patients on or off prophylactic antibiotics. For the first definition, we identified a symptomatic exacerbation event as 2 or more new symptoms lasting for 2 or more consecutive days as recorded by the patient in their diary, whether or not they received additional treatment for that. ./cache/cord-265563-1k8v0luz.txt ./txt/cord-265563-1k8v0luz.txt