id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-325155-lqzgz6p3	Gallo, Juan E.	Hypertension and the roles of the 9p21.3 risk locus: classic findings and new association data	2020-09-15		.txt	text/plain	5285	268	49	Two adjacent haplotype blocks characterize the 9p21.3 cardiovascular risk locus: left, the block or island containing the first part of the p15 gene and its wellcharacterized promoter, in which we observed clearly elevated associations (red) with blood pressure (DBP, SBP) and/or hypertension in a Colombian and a European study sample, and right, the block hypertension and BP association 'Hypertension island' * (haplotype block < 60 kb) Lead CVD risk SNPs (haplotype block < 60 kb) Furthermore, in the European blood pressure studies [15, 16] genome-wide significance of DBP associations was attained, outside of the classic 9p21.3 CVD risk locus and its flanking regions, in the next gene MTAP (see Figure 2 and Theory), with a lowest p-value of 1.3 × 10 −10 for the sentinel SNP rs4364717 (red asterisk and red horizontal bar at left in Figure 2 ; see also the LocusZoom plot in Supplementary Material S3.2) .	./cache/cord-325155-lqzgz6p3.txt	./txt/cord-325155-lqzgz6p3.txt