id author title date pages extension mime words sentences flesch summary cache txt cord-256652-ent4vu3z Tan, Joshua A public antibody lineage that potently inhibits malaria infection by dual binding to the circumsporozoite protein 2018-03-19 .txt text/plain 6576 329 46 investigate this response at high resolution, we isolated IgM and IgG monoclonal antibodies from Tanzanian volunteers who were immunized by repeated injection of irradiated PfSPZ and who were found to be protected from controlled human malaria infection (CHMI) with infectious homologous PfSPZ. investigate this response at high resolution, we isolated IgM and IgG monoclonal antibodies from Tanzanian volunteers who were immunized by repeated injection of irradiated PfSPZ and who were found to be protected from controlled human malaria infection (CHMI) with infectious homologous PfSPZ. These findings, combined with data from peptide array experiments ( Supplementary Fig. 7) , identify the N-terminal junction binding site of the most potent neutralizing antibodies as including the first unit of the NANP repeat region and flanking non-repeat sequences, providing a molecular basis for the dual specificity of these antibodies. ./cache/cord-256652-ent4vu3z.txt ./txt/cord-256652-ent4vu3z.txt