id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-103683-xcsal8vk	Rafie, K.	The structure of enteric human adenovirus 41 - a leading cause of diarrhea in children	2020-10-16		.txt	text/plain	6635	354	53	The structure also provides new insights into conserved aspects of HAdV architecture such as a proposed location of protein V, which links the viral DNA to the capsid, and assembly-induced conformational changes in the penton base protein. Compared to the two other reported structures of human adenoviruses, HAdV-C5 (PDB: 6B1T (20) ) and HAdV-D26 (PDB: 5TX1(21)), the sequence identity of the capsid proteins ranges from 30-80% (Supplementary Table 3 ). The HAdV-F41 penton base undergoes assembly-induced conformational changes Located on the five-fold symmetry axes of adenovirus capsids, the penton base (PB) protein forms a homopentamer that contains integrin-binding motifs and serves as an assembly hub connecting the icosahedral capsid to the fibers (Fig. 1A) . The DNA-binding protein V is located at a conserved position at the inner face of the capsid After initial model building of the virion at pH=7.4, the asymmetric unit contained five peptide chains that still had not been assigned an identity.	./cache/cord-103683-xcsal8vk.txt	./txt/cord-103683-xcsal8vk.txt