id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-341745-2txzi7kb	Singh, S.	Efficacy and Safety of Hydroxychloroquine and Chloroquine for COVID-19: A systematic review	2020-05-26		.txt	text/plain	4771	346	50	RESULTS: After a review of 175 citations, we included 5 clinical trials (total of 345 patients), 9 observational studies (n = 2529), and 6 additional studies (n = 775) reporting on the QT interval. CONCLUSIONS: Our systematic review of reported clinical studies did not identify substantial evidence to support the efficacy of hydroxychloroquine or chloroquine in hospitalized COVID-19 patients and raises questions about potential harm from QT prolongation and increased mortality. Our systematic review of reported clinical studies did not identify substantial evidence to support the efficacy of hydroxychloroquine or chloroquine in hospitalized COVID -19 patients and raises questions about potential harm from QT prolongation and increased mortality. We included both published and unpublished clinical trials and observational studies that reported on chloroquine and hydroxychloroquine use either as a single drug or in combination with azithromycin to treat patients hospitalized patients with COVID-19.	./cache/cord-341745-2txzi7kb.txt	./txt/cord-341745-2txzi7kb.txt