id author title date pages extension mime words sentences flesch summary cache txt cord-334849-8rblgq9b LoPresti, Marissa The Role of Host Genetic Factors in Coronavirus Susceptibility: Review of Animal and Systematic Review of Human Literature 2020-08-12 .txt text/plain 7290 456 45 1 As with many complex diseases, the reality for most individuals likely involves a combination of genetic -including viral and host genetics -and non-genetic Relative to other coronaviruses, SARS-CoV-2 has unique biological properties and related clinical impact, but data regarding other coronaviruses may be relevant. This can help populate lists of genes that -along with data from related biological studies -may bear scrutiny in the developing and important large-scale host genetic 6 and porcine epidemic diarrhea virus (PEDV)in pigs. In various species, efforts have focused on genes encoding the relevant coronavirus receptor, including effects of viral and host genetic changes and how these may impact the disease process. 30 In humans (see Tables 1 and S2 and Figures 3 and 4 for details on human studies of these genes, including specific references), studies of specific ACE2 polymorphisms have not shown significant associations with SARS-CoV-1 susceptibility or outcome. ./cache/cord-334849-8rblgq9b.txt ./txt/cord-334849-8rblgq9b.txt