id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-325201-yoy7kdli	Timsit, Jean-François	Year in review in Intensive Care Medicine 2014: III. Severe infections, septic shock, healthcare-associated infections, highly resistant bacteria, invasive fungal infections, severe viral infections, Ebola virus disease and paediatrics	2015-03-26		.txt	text/plain	9122	455	41	This third article for the 2014 Year in Review will report publications from intensive care on severe infections (including endocarditis and peritonitis), septic shock, healthcare and ventilator associated pneumonia, highly resistant bacteria, antimicrobial therapy (including antibiotic stewardship, therapeutic drug monitoring and deescalation), invasive fungal infections, severe viral infections, Ebola virus disease and paediatrics. While it is now well recognized that early appropriate antimicrobial therapy reduces infection-related morbidity and mortality in the critically ill patients, the importance of pharmacodynamic (PD) dosing to optimize drug exposure continues to evolve. Bacteremia is one of the major causes of nosocomial infection in the intensive care unit (ICU), ICU-acquired bloodstream infection (ICU-BSI) is associated with increased morbidity and length of stay, resulting in excess costs and high mortality of critically ill patients. In addition, in a small randomized study on the efficacy of empiric treatment of suspected ventilator associated pneumonia in patients with candida colonization of the respiratory tract did not prove to be effective [40] .	./cache/cord-325201-yoy7kdli.txt	./txt/cord-325201-yoy7kdli.txt