id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-324859-0yuhb5dl	Mulchandani, Rubina	Deciphering the COVID‐19 cytokine storm: Systematic review and meta‐analysis	2020-11-02		.txt	text/plain	6715	343	46	In this context, we sought to undertake a systematic review and meta-analysis of available evidence to understand the pattern of host immune response in patients diagnosed with COVID-19 and how the levels of inflammatory and immunological markers vary according to the severity or stage of the disease. To understand the pattern of host immune response and summarize evidence for the difference in the levels of immunological and inflammatory biomarkers associated with cytokine storm, between COVID-19 patient groups of varying disease severity. Studies measuring the immunological and inflammatory indicators of cytokine storm in adult patients with a confirmed diagnosis of COVID-19, and comparing them between severe and non-severe (mild-moderate) cases, were eligible to be included in our review. Outcomes included circulating levels of interleukins (IL-6, IL-8, IL-10 and others depending on availability of estimates), tumour necrosis factor-alpha and T-lymphocyte counts (CD4+ T cells and CD8+ T cells) that have been widely reported in relation to the cytokine storm in patients having severe COVID-19.	./cache/cord-324859-0yuhb5dl.txt	./txt/cord-324859-0yuhb5dl.txt