id author title date pages extension mime words sentences flesch summary cache txt cord-301805-sb0ij8k7 Fuentes, Blanca Glycemic variability: prognostic impact on acute ischemic stroke and the impact of corrective treatment for hyperglycemia. The GLIAS-III translational study 2020-11-04 .txt text/plain 3834 235 44 METHODS: This translational study consists of two studies conducted in parallel: The first study is an observational, multicenter, prospective clinical study in which 340 patients with acute IS will be subcutaneously implanted a sensor to continuously monitor blood glucose levels for 96 h. DISCUSSION: The GLIAS-III study will be the first translational approach analyzing the prognostic influence of GV, evaluated by the use of subcutaneous glucose monitors, in acute stroke. We hypothesized that GV, assessable by means of continuous subcutaneous monitoring devices, could act as a powerful prognostic predictor of mortality, possibly higher than assessment of mean or maximum blood glucose levels and that the different treatment regimens used in routine clinical practice could modify glycemic variability. No laboratory data other than HbA1c will be collected for Discussion: The GLIAS-III study will be the first translational approach analyzing the prognostic influence of GV, evaluated by the use of subcutaneous glucose monitors, in acute stroke. ./cache/cord-301805-sb0ij8k7.txt ./txt/cord-301805-sb0ij8k7.txt