id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-017955-oipail5l	Wilkie, David A.	The Ophthalmic Examination as It Pertains to General Ocular Toxicology: Basic and Advanced Techniques and Species-Associated Findings	2013-08-29		.txt	text/plain	12662	668	46	However, if the purpose of such a study is to screen for adverse effects on any ocular tissue including, at a minimum, the adnexal structures (eyelids and conjunctiva), anterior segment (cornea, anterior chamber, iris, and lens), and posterior segment (vitreous and fundus), the following must be included: Additional procedures may be included depending on the objective of the examination. Additional examination procedures such as direct ophthalmoscopy, corneal staining, tonometry, pachymetry, fluorescein angiography, photographic documentation (anterior or posterior segment), electrodiagnostic testing, ultrasonography, OCT, and other tests may be indicated depending on the study and toxicologic effects of interest. Examples of ocular findings that may be progressive during the course of the study and Common background abnormalities will vary by species, but may include ocular trauma associated with shipping, congenital embryonic remnants such as persistent pupillary membrane (PPM) and persistent hyaloid artery (PHA), extravasation of blood in association with a PHA, corneal opacity/dystrophy, coloboma (iris, lens, choroid), cataract, micropapilla, optic nerve hypoplasia, and retinal dysplasia [1, 7-9, 11, 16-28] .	./cache/cord-017955-oipail5l.txt	./txt/cord-017955-oipail5l.txt