id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-011335-pamcpi8n	Govindan, Vedavalli	Cerebral venous volume changes and pressure autoregulation in critically ill infants	2020-03-10		.txt	text/plain	3809	205	41	STUDY DESIGN: In a prospective study of newborns undergoing positive-pressure ventilation, we calculated coherence between continuous mean arterial pressure (MAP) and cerebral near-infrared spectroscopy hemoglobin difference (HbD). For this study, our goals were to evaluate the association between cerebral venous volume changes at the ventilator frequency on the development of (1) cerebral pressure passivity, and (2) brain injury, in newborn infants undergoing intensive care. The study population included infants with three broad categories of illness, all known to be at significant risk of brain injury, namely, term/ near-term infants with either perinatal hypoxic-ischemic encephalopathy (HIE) or congenital heart disease (CHD), as well as preterm infants (<37 weeks of gestational age (GA)). In this study, we identified a significant relationship between the magnitude of fluctuations in CBV associated with positive-pressure ventilation, and the presence of cerebral pressure passivity, in a population of critically ill newborn infants.	./cache/cord-011335-pamcpi8n.txt	./txt/cord-011335-pamcpi8n.txt